Dissertations / Theses on the topic 'ALIA'
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Alia, Najib [Verfasser]. "Optimal control of ladle stirring / Najib Alia." Berlin : Freie Universität Berlin, 2019. http://d-nb.info/1200408136/34.
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Afzal, Alia [Verfasser], and Philipp [Akademischer Betreuer] Sibbertsen. "Essays on fractional cointegration and spurious long memory / Alia Afzal ; Betreuer: Philipp Sibbertsen." Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2019. http://d-nb.info/1194158595/34.
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Duffy, Nikolai. "Inter alia : Steve Erickson, Rosmarie Waldrop, Lydia Davis and the lightening of meaning." Thesis, Goldsmiths College (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420930.
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Inter Alia is structured principally around a cross-threaded sequence of analyses that consider the property of meaning in the work of Steve Erickson, Rosmarie Waldrop, and Lydia Davis. It aims at a sustained formal and thematic consideration of the critical disturbance with which their respective texts inflect grammatology. In each writer this critical disturbance is determinable commonly as what might be termed a rifting of language and thinking toward the a-grammatical. The primary formal and thematic modalities of writing become indivisible from an attempt to think language outside its accepted propensity to mean. They seek to put into question the governable self-sufficiency of meaning by thinking the possibility of another language and of another meaning; a language and a meaning, that is to say, of lightening. In so doing, the folds of their texts are indivisible from a set of inter-related reflections concerning, among other things, intelligibility, materiality, commonality, as well as their respective inverses: ambiguity, immateriality, and exceptionality. Where much Anglo-American postmodernism has been concerned with the dual crises of perception and representation, the internal logic of 'lightening' seeks to shift the consideration from an exigency of illumination to one of alleviation in which meaning is nothing other than an inter alia. Establishing a dialogue between these concepts and their modulation in the work of such thinkers as Maurice Blanchot, Emmanuel Levinas, Jacques Derrida and Jean-Luc Nancy, the discretion of lightening is shown to emblematise the principle preoccupation of contemporary literary-philosophical reflections concerned with ·the discursive and social implications of disorder and ex-centricity.
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Fischer, Marie. "'n Ondersoek na die behoeffes van studentverpleegkundiges met betrekking tot die ontwikkeling van basiese studievaardighede." University of Western Cape, 1997. http://hdl.handle.net/11394/7474.
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>Magister Scientiae - MScDie grondgedagte vir hierdie studie spruit voort uit die verantwoordelikheid van die verpleegdosente om die vermoëns van studentverpleegkundiges tot selfgerigte studie te ontwikkel. Selfgerigte studie vereis onder andere, die vermoë om inligting te kan vind, te verwerk, en toe te pas in die praktyk. Hierdie vaardighede is essensiële voorvereistes vir onafhanklike professionele praktisering. Die ontwikkeling van die genoemde vaardighede impliseer 'n multi-dimensionele benadering wat die student in totaliteit aanspreek. Voorts vereis dit nougesette betrokkenheid van die student by sy/ haar studies. Laasgenoemde veronderstel, onder andere, egter dat studente oor sekere essensiële vaardighede, in verband met leer en studie, beskik. Uit die literatuur blyk dit duidelik dat sekondêre onderwys, oor die algemeen, studente nie voldoende voorberei vir tersiêre onderwys nie. Deur middel van hierdie studie wou die navorser dus antwoorde probeer vind op die vraag of studenteverpleegkundiges behoeftes ervaar aan leiding met betrekking tot spesifiek geïdentifiseer studievaardighede, die leiding wat verskaf word en of daar leemtes bestaan in die leiding wat studente reeds ontvang. Nadat die studieterrein afgebaken is, is verskillende terme en begrippe, grondliggend tot die studie, omskryf en in perspektief gestel. Hoofstuk twee is gewyaan 'n bespreking van die konsepte leer, -probleme en studie binne die perspektief van hierdie studie, asook verbandhoudend relevante begrippe. Aandag is in die daaropvolgende twee hoofstukke geskenk aan, onderskeidelik, spesifieke stud ievaardighede verbandhoudend tot die versameling van inligting en studievaardighede verbandhoudend tot die benutting van inligting.
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Bailey, Hunter M. "Via Media Alia : reconsidering the controversial doctrine of universal redemption in the theology of James Fraser of Brea (1639-1699)." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/3266.
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James Fraser of Brea’s significance in Scottish theological history stems principally from his controversial doctrine of universal redemption which led to schisms within the Associate Synod and the Reformed Presbytery in the mid-18th century. During those disputes, several assumptions were made concerning his doctrines that have endured, thereby hindering the development of a more objective interpretation of Fraser's thought. Recent scholarship has begun the re-evaluation of his place in the development of Scottish theology and this thesis continues the process by seeking to exonerate Fraser from the unwarranted and reductionist accusations that have hitherto obscured his doctrine of redemption. This thesis advances a new and more accurate interpretation of Fraser’s doctrine of Christ’s redemption. By broadening discussions beyond the single criterion of the scope of Christ’s redemption, it also helps develop a more precise understanding of the fundamental issues of the orthodox Reformed position upon redemption during the 17th century. In order to provide a context for scrutinizing Fraser’s formulations, the debates surrounding the doctrine of redemption throughout the 16th and 17th centuries have been explored. In addition, a systematic evaluation of Fraser’s views on assurance, God’s eternal decrees, federal theology and justifying faith has been undertaken to construct a framework through which a more accurate interpretation of his doctrine of universal redemption has been achieved. Divided into three sections, this thesis begins with two contextualizing chapters. These establish the parameters of this thesis as well as detail several key developments in the doctrine of redemption throughout the 16th and 17th centuries related to determining the proper interpretation of Fraser’s doctrine of universal redemption. Following this introductory section, the second section of this thesis, which constitutes the main body in four chapters, scrutinizes Fraser’s doctrine of redemption in relation to his expressed purpose in writing and his fundamental doctrinal commitments, namely his unwavering fidelity to covenantal absolutism and redemptive particularism. The final section of this thesis is the conclusion, wherein scholars are encouraged to reconsider how they classify the doctrine of redemption and, specifically, how they understand Fraser’s doctrine of redemption in relation to the redemptive theories of his contemporaries. It is commonly recognized that Fraser deviated from the Reformed orthodox norms of the 17th century by arguing for a broader scope of Christ’s redemption, one that included the reprobate as well as the elect. This thesis moves beyond this basic understanding of his theology in two ways. Firstly, it explores why Fraser determined it was necessary to depart from the traditional presentation of Christ’s redemption and secondly it identifies how his adoption of the two-fold design of redemption corresponded to the more foundational theological commitments of his Reformed contemporaries. Since most previous interpretations have run together the three different positions, Fraser’s perspective has been carefully compared and contrasted with the redemptive paradigms proposed by the Arminians and the Hypothetical Universalists. This thesis will challenge such a confusion of theologies, arguing instead that Fraser’s doctrine of redemption truly represents via media alia. In order to fill the gaps left by earlier examinations of Fraser’s theology which concentrated upon his Treatise on Justifying Faith, for the first time equal consideration has been given to all of Fraser’s writings. Even the voluminous doctoral study by Duncan Fraser (1944), proving that Fraser of Brea employed the theme of Christ’s universal redemption throughout his writings, failed to provide an adequate analysis of how Fraser’s doctrine of redemption fitted into his own theological system or into the context of the Reformed community of 17th century Europe. This thesis provides just such an analysis.
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Mattos, Lilian de Fátima. "O uso das novas tecnologias nas aulas de produção de textos a partir de uma metodologia que alia o paradigma emergente ao trabalho com projetos." Florianópolis, SC, 2003. http://repositorio.ufsc.br/xmlui/handle/123456789/84531.
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.Made available in DSpace on 2012-10-20T10:11:02Z (GMT). No. of bitstreams: 0
Devido as rápidas transformações impostas pela globalização, escola e professores necessitam refletir criticamente sobre suas estratégias pedagógicas. Acreditamos que a metodologia do Paradigma Emergente, baseada na tríade - holística, progressista e ensino como pesquisa - aliada a projetos e novas tecnologias, levará os alunos a desenvolver habilidades que os ajudarão a exercer a plena cidadania. Esta metodologia pretende que o professor atue como mediador na sala de aula, melhorando o relacionamento interpessoal entre os alunos, promovendo a importância da pesquisa, o valor do trabalho em grupo de maneira a analisar e produzir textos bem como despertar a consciência crítica e reflexiva. Complementando, a metodologia tenciona alertar os estudantes de que o conhecimento é a chave para o progresso material, físico e espiritual. E que o conhecimento se conquista somente através do incessante aprendizado, o qual lhe proporcionará as ferramentas para serem verdadeiros cidadãos capazes de construir um mundo melhor.
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Rashed, Alia [Verfasser], and Guido [Akademischer Betreuer] Sauter. "Anwendung von MALDI (matrix-assisted laser desorption/ionization) Imaging zur Identifikation von relevanten biologischen Veränderungen auf TMA (Tissue Microarrays) und Großschnitten / Alia Rashed. Betreuer: Guido Sauter." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2014. http://d-nb.info/1054422710/34.
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Dogan, Guray. "Determination Of Ambient Levels And Sources Of Volatile Organic Compounds In Izmir-aliaga Region." Phd thesis, METU, 2013. http://etd.lib.metu.edu.tr/upload/12615633/index.pdf.
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In this study, atmospheric levels and sources of VOCs at Aliaga industrial area was investigated. For this, VOC concentrations were measured at two monitoring stations through winter and summer campaigns in 2005 and 2006. Sampling stations were located in downtown Aliaga and downwind of industrial facilities, approximately 500 m to the south east of Horozgedigi village. After the summer sampling, another temporary station was installed in between PETKIM and TÜPRAS, named as TÜ
PRAS Station to generate TÜ
PRAS and PETKIM profiles. More than 50 species were measured in all stations. In all stations, toluene has the highest contribution to total VOC concentration. Toluene is followed by m,p-xylene and benzene. While higher concentrations of traffic related VOCs were measured at Aliaga station, VOCs from industrial solvents and industrial processes were higher at Horozgedigi station. The concentration levels in Aliaga and Horozgedigi are found to be comparable to the other industrial regions reported in the literature. Investigation of episodes, diurnal variations of VOCs and meteorological parameters showed that PETKIM and TÜ
PRAS emissions affect the concentrations levels at Horozgedigi and Aliaga stations. Source profiles of PETKIM and TÜ
PRAS are determined by using the TÜ
PRAS station data set. 2-methyl-hexane, benzene and 2,2,3-tri-methyl-butane+2,3-di-methyl-pentane are found to be good markers of PETKIM emissions. Ten different VOC sources were identified in the region. These were gasoline exhaust, diesel exhaust, natural gas use, gasoline evaporation, industrial emissions-1, natural gas construction, non-industrial solvent use, industrial emissions-2, PETKIM emissions, and mixed emissions from PETKIM and shipbreaking facilities.
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Medar, Abdul Samad. "Arabic as educational Muslim content in South African context: A pedagogical survey and evaluation with special reference to Secondary Schools." University of the Western Cape, 1987. http://hdl.handle.net/11394/8201.
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Magister Educationis - MEdThe aim of this study is to investigate ·and outline the importance and significance of Arabic in the South African context. The study investigates inter alia the part played by the early Muslim settlers, political exiles and the pioneers who made possible the preservation of Islamic faith and culture. This study demonstrates that the period from 1652 to date had been a period of considerable development, expansion and _enlightenment of Arabic. The study revealed inter alia that only Indian schools under the Department of Indian Affairs (now Department of Education and Culture) offered Arabic which fully satisfied the Muslim Community's demands. 1975 marks the beginning of Arabic as a language in Indian secondary schools. The Muslim pupil is given the basic grounding in the understanding of both the Quran and the Hadith. Some suggestions regarding aspects of an effective didactic approach concludes this presentation.
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Gouws, Andre. "Die voorligtingsbehoeftes van Sekondêre leerlinge in 'n benadeelde gemeenskap en die implikasies daarvan vir hul groepvoorligtingsprogram:'n opvolgstudie." University of the Western Cape, 1990. http://hdl.handle.net/11394/8407.
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Philosophiae Doctor - PhDHierdie ondersoek is onderneem om die voorligtingsbehoeftes van leerlinge in sekondêre Kleurlingskole in Wes-Kaapland te bepaal en die implikasies daarvan vir hul groepvoorligtingsprogram aan te toon. Die navorser het ook die bevindings van die huidige ondersoek met die van sy meningsopnames in 1979 en 1983 vergelyk. 'n Literatuurstudie is aangewend om die aard, doelstellings en beginsels van groepvoorligting te kelingstake van die Westerse en Afrikaanse - adolessent te ondersoek, formuleer, die ontwikspesifiek die Suiden lig te werp op die spesifieke ontwikkelingsbehoeftes en -probleme waarmee Kleurlingjeugdiges te kampe het. Vraelyste deur leerlinge en skoolvoorligters voltooi, het die relevantheid van die amptelike program se groepvoorligtingsonderwerpe beoordeel, aangedui watter moontlik bestaande onderwerpe kan vervang of daarby gevoeg kan word, en kommentaar oor die inhoud en aanbieding van die huidige program gelewer. Ten opsigte van di,e~~rd van groepvoorligting is bevind dat die huidige Handleiding en Program slegs enkele vereistes toelig en dus hersien behoort te word om alle essensiale aspekte van voorligting te dek. Die afwesigheid van spesifieke dQelá!allinaá vir groepvoorligting in die amptelike handleiding voorsien nie die nodige riglyne aan voorligters vir hul taak nie, en dus is 'n reeks doelstellings in funksionele terme geformuleer. Havighurst (1972) se formulering van adolessente ontwikkelingstake, aangevul deur die navorsing van Burns (1988), kan as n bruikbare raamwerk vir die terrein van groepvoorligting gebruik word. Dis is voorgestel dat elke sekondêre standerd persoonlikheidsvoorligting, voorligting, opvoedkundige voorligting en voorligting behoort te ontvang. sosiale beroeps- Ten opsigte het die onderwerpe van die inhoud van 'n groepvoorligtings programliteratuurstudie onder andere aangetoon dat by die leerlinge se ontwikkelingsvlak en veranderende behoeftes aansluiting moet vind, die program buigsaam moet wees om by plaaslike vereistes te kan aanpas, en dat die klem op die bevordering van leerlinge se persoonlike waardestelsels behoort te val Dit het uit die resultate van die empiriese ondersoek geblyk dat beide leerlinge en voorligters die oorgrote meerderheid onderwerpe van die amptelike program as van besondere belang beskou. Weens die erns en omvang van die voorligtingsbehoeftes wat geIdentifiseer is, blyk egter 'n aansienlike uitbreiding van die program aangewese te wees. Binne elke standerd behoort 'n beperkte aantal "verpligte" onderwerpe aangebied te word, terwyl minstens die helfte van dievoorligtingstyd aan opsionele onderwerpe in ooreenstemming met leerlinggroepe se besondere behoeftes bestee behoort te word. Persoonlikheids- en sosiale voorligting enersyds en opvoedkundige en beroepsvoorligting andersyds moet die twee gelykwaardige komponente van so 'n program uitmaak Dié response van die leerlinge en voorligters stem in 'n hom mate met die van die vorige ondersoeke ooreen. n Veel groter sensitiwiteit ten opsigte van gemeenskaps probleme en interpersoonlike verhoudings, asook 'n sterker behoefte aan probleemoplossingsvaardighede en geslags- en beroepsvoorligting het egter geblyk. Dus is onder andere aanbeveel dat geslagsvoorligting as n afsonderlike program aangebied en die bestaande samewerking met privaat tingsinstansies voortgesit sal word. In verband met die aanbieding van groepvoorligtingslesse is die skep van 'n ontspanne atmosfeer, bevorderlik vir aktiewe leerlingdeelname, vrye meningswisseling en persoonlike meningsvorming, beklemtoon. Bepaalde administratiewe maatreels is voorgestel ten einde die sukses verseker. van 'n hersiene groepvoorligtingsprogram te help Verder is sekere aanbevelings gemaak om voorligters se professionele status te verhoog.
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Wesso, Iona. "Science text: Facilitating access to physiology through cognition-based reading intervention." University of the Western Cape, 1995. http://hdl.handle.net/11394/8485.
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Philosophiae Doctor - PhDReading and understanding science text is the principal means by which students at tertiary level access scientific information and attain scientific literacy. However, understanding and learning from science texts require cognitive processing abilities which students mayor may not have. If students fail to understand scientific text, their acquisition of subject knowledge and expertise will be impeded and they will fail to develop into thinking and independent learners, so crucial for academic progress and achievement. A major assumption in this study is thus that in order to increase access to science subjects there is a need to explicitly teach the thinking abilities involved in learning science from text. A review of the literature showed that while reading to learn from scientific text poses special challenges to students faced with this unfamiliar genre, little is known about reading (and thinking) for science learning. A synthesis of current research which describes the neglected interface between science learning, science reading and cognition is given in the literature review of this study. This synthesis highlights, in particular, the parallel developments in research into science learning and reading; the lack of integration of research in these areas; the absence of investigations on science reading located within the cognitive domain; and the absence of research into reading as it affects cognition and cognition as it affects reading in subject-specific areas such as physiology Possibilities for improving students' cognitive performance in reading to learn through intervention were considered from a cognitive perspective. From this perspective, students' observable intellectual performance can be attributed to their underlying knowledge, behaviour, and thought processes. Accordingly, the mental processes involved in comprehending scientific concepts from text and the cognitive processes which the students bring to the learning situation become highly relevant to efforts to improve cognitive skills for learning science Key questions which were identified to serve as a basis for intervention included: a) What cognitive abilities are needed for competent reading comprehension as demanded by physiology text?; b) How adequate is the cognitive repertoire of students in dealing with physiology text? With regard to these questions a catalogue of cognitive functions as formulated by Feuerstein et al (1980) was identified as optimally suited for establishing the cognitive match between reading tasks and students. Micro-analyses of the cognitive demands of students' textbook material and the cognitive make-up of second-year university students revealed a profound mismatch between students and their learning material. Students lacked both comprehension fostering and comprehension monitoring abilities appropriate to the demands of the learning task. The explication of the cognitive requirements which physiology text demands served as a basis for systematically designing instruction whereby appropriate intellectual performance for scientific comprehension from text may be attained Subsequent intervention was based on the explicit teaching of thinking abilities within the context of domain-specific (physiology) knowledge. An instructional framework was developed that integrated cognitive learning theories and instructional prescriptions to achieve an effective learning environment and improve students' cognitive abilities to employ and extend their knowledge. The objective was that the instructional model and resultant instructional methods would ensure that students learn not only the desired kinds of knowledge by conceptual change, but also the thought processes embedded and required by reading scientific material for appropriate conceptual change to take place. Micro-analysis of the cognitive processes intrinsic to understanding physiology text illuminated cognitive demands such as, for example, the ability to: transform linearly presented material into structural patterns which illuminate physiological relationships; analyse conceptually dense text rich in "paradoxical jargon"; activate and retrieve extensive amounts of topic-specific and subject-specific prior knowledge; to visualise events; and contextualise concepts by establishing an application for it. Within the above instructional setting, the study shows that the notion of explicitly teaching the cognitive processes intrinsic to physiology text is possible. By translating the cognitive processes into cognitive strategies such as assessing the situation, planning, processing, organisation, elaboration, monitoring and reflective responses, the heuristic approach effectively served to guide students through various phases of learning from text. Systematic and deliberate methods of thought that would enhance students problem-solving and thinking abilities were taught. One very successful strategy for learning from physiology text was the ability to reorganise the linearly presented information into a different text structure by means of the construction of graphic organisers. The latter allowed students to read systematically, establish relationships between concepts, identify important ideas, summarise passages, readily retrieve information from memory, go beyond the given textual information and very effectively monitor and evaluate their understanding In addition to teaching appropriate cognitive strategies as demanded by physiology text, this programme also facilitated an awareness of expository text conventions, the nature of physiological understanding, the value of active strategic involvement in constructing knowledge and the value of metacognitive awareness. Also, since the intervention was executed within the context of physiology content, the acquisition of content-specific information took place quite readily. This overcame the problem of transfer, so often experienced with "content-free" programmes. In conclusion, this study makes specific recommendations to improve science education. Inparticular, the notion of teaching the appropriate cognitive behaviour and thought processes as demanded by academic tasks such as reading to learn physiology seems to be a particularly fruitful area into which science educational research should develop and be encouraged.
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Konin, Alla Marcellin Vieillard-Baron Jean-Louis. "Les modalités spécifiques de la raison politique critique religieuse et engagement politique chez Spinoza /." [S.l.] : [s.n.], 2008. http://theses.edel.univ-poitiers.fr/theses/2008/Konin-Alla/2008-Konin-Alla-These.pdf.
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Konin, Alla Marcellin. "Les modalités spécifiques de la raison politique : critique religieuse et engagement politique chez Spinoza." Poitiers, 2008. http://theses.edel.univ-poitiers.fr/theses/2008/Konin-Alla/2008-Konin-Alla-These.pdf.
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Notre travail interroge la religion et la politique à la lumière de la critique du spinozisme. Il s'en dégage que : dans la forme, la raison discursive, et critique s'oppose à la foi comme révélation et certitude non-réfléchie mais leur contenu (l'Absolu) les unit. Dès lors, la raison élève le sentiment religieux (le fini accède à l'Infini par la réflexion), inversement, la foi fonde la rationalité. Cependant, nous nous demandons si cette rationalité de la foi ne nie pas sa spécificité. Envisager avec Spinoza la séparation de la philosophie et de la théologie afin de permettre la liberté de pensée et d'expression. En effet, l'analyse de la connaissance rationnelle dans son rapport avec la connaissance théologique nous conduit à sceller la distinction entre le théologien et le philosophe d'une part et de l'autre entre le théologien et le politique. Le conatus spinoziste doit pouvoir permettre de vaincre l'asservissement et les préjugés, et conduire les individus à la liberté et au salut de la sociétéThe thesis examines the relationship between religion and politics from the Spinozist critical perspective. In terms of form, discursive and critical reasoning is opposed to faith which can be characterised as a non-analytical certainty taking the form of revelations. In terms of content however, reason and faith are united by their shared content a sense of the Absolute. In these circumstances reason is able to promote religious feeling, the finite becoming infinite thanks to meditative thought ;conversely, faith can provide a basis for rationality. Nonetheless, is it not possible to see this rationality of faith as a denial of that which specifically defines faith ? Spinoza's aim was to separate philosophy from theology so as to liberate thought and freedom of expression. As a matter of fact, the analysis of rational understanding and its relations with theological knowledge gives us a better grasp of what differentiates the theologian and philosopher on the one hand, and the theologian and politician on the other. Spinoza's 'conatus' should allow us to overcome subordination and prejudice, taking us toward liberation and the salvation of society
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Mäkelä, V. (Ville). "Alfa-D-Mannosidaasit ja Alfa-Mannosidoosi." Bachelor's thesis, University of Oulu, 2018. http://urn.fi/URN:NBN:fi:oulu-201804061443.
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Alfa-mannosidaasit ovat ryhmä entsyymejä jotka osallistuvat glykoproteiinien rakennukseen ja kierrätykseen leikkaamalla mannosidaasien välisiä alfa-sidoksia hydrolyysillä. Alfa-mannosidoosi on sairaus joka johtuu lysosomaalisen alfa-mannosidaasin mutaatioista. Sairauden vakavuus riippuu mutaation tyypistä ja sijainnista. Jos entsyymin toiminta on vain vähän hidastunut, oireet voivat olla lievät ja helposti hallittavissa, kun taas vakava mutaatio voi johtaa aikaiseen kuolemaan. Oireisiin kuuluvat kehitysvammaisuus, kuulo- ja luusto-ongelmat ja immuunikato. Oireet johtuvat kertyvien sokeriketjujen laajentamista lysosomeista, jotka vievät tilaa muilta soluelimiltä ja vaikeuttavat solun toimintaa. Parannusta sairauteen ei ole, mutta sitä voidaan helpottaa joko oirekohtaisilla hoidoilla tai entsyymikorvaushoidolla.
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Paula, Denise Toledo de. "Relações entre localização geográfica, perfil sócio-econômico e as condições higiênico-sanitárias dos açougues no município de Belo Horizonte/MG." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/ALOA-6MMNCB.
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The objective of this paper is to profile the cleanliness..ie- Hygiene and Sanitation- of Butcher Shops/Meat Markets in Municipal Belo Horizonte-MG, by way of routine inspections utilized by the Sanitation Department. The Meat Market/Butcher Shops were classified not only by their regional administrative parameters but by their Socio-Economic Class whose results were individualized for each of those parameters. 212 Meat Markets/Butcher Shops were analyzed out of the 1059 registered with the Sanitation Department analyzing the results of the the routine inspections and subsequent points given, each butcher shop recieved a Certificate of Cleanliness ranging from Bad to Excellent. Utilizing the data collected from the inspections, the Main Characteristics and thus, deficiencies, were found for each of the 9 Administrative Regions and the 6 Socio-economic classes determined for the region. This information becomes and important factor for future inspections directed by the Sanitation Department. It was noted that the majority of the certificates of cleanliness administrated were in the range of Regular to Good which demonstrated the neccesity of stricter actions from the Sanitation Dept. in all the Butcher Shop and Meat Markets in the Region. It was also noted that there must be an investment increase in the Municipal Sanitation Dept., mainly in the Human Resources Dept., thus establishing the continual capacitation of Veterinarians and inspectors and the importance of divulging Educative Campaigns for the general population in this way creating a sort of Sanitary conciousness enabling each citizen to become their own Health Inspector.Este trabalho teve o objetivo de caracterizar o perfil higiênico-sanitário dos açougues do Município de Belo Horizonte - MG, através do Roteiro de Vistoria utilizado pela Vigilância Sanitária Municipal quando das vistorias realizadas nesses estabelecimentos. Os açougues foram classificados quanto aos parâmetros Regional Administrativa e Classe Sócio-Econômica, sendo a amostragem individualizada para cada um dos parâmetros. Foram analisados 212 açougues dos 1059 cadastrados pela Vigilância Sanitária Municipal, e em virtude da pontuação final recebida, utilizando o Roteiro de Vistoria, foi conferido ao estabelecimento um Selo de Qualidade, que variou de Ruim a Excelente. Através da análise dos resultados encontrados foram detectadas as principais características e, conseqüentemente, as deficiências dos açougues de cada uma das 9 Regionais Administrativas e das 6 Classes Sócio-Econômicas determinadas para o Município, constituindo-se em importante subsídio para o direcionamento das futuras ações da Vigilância Sanitária. Ficou constatado que os Selos de Qualidade que predominaram, em geral, em todas as Regionais Administrativas e em todas as Classes Sócio-Econômicas foram o Bom e o Regular, demonstrando necessidade de atuação mais efetiva da Vigilância Sanitária nos açougues do Município. Constatou-se, também, a necessidade de se aumentar os investimentos para a Vigilância Sanitária Municipal, principalmente no que diz respeito aos recursos humanos, estabelecendo capacitação contínua de Médicos Veterinários e Fiscais; e a urgência em se divulgar campanhas educativas para a população, para que se forme uma consciência sanitária e que cada cidadão se torne também um vigilante em saúde.
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Chow, Felipe Coser. "Avaliação das características físico-químicas e microbiológicas de carne mecanicamente separada de frango de diferentes marcas comerciais." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/ALOA-8QVL5T.
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Since the latest 50s, mechanically deboned chicken meat (MDCM) has been used by industry as a raw matter for meat products. Such practice has become quite usual nowadays and because of productive and behavior reasons and even due to his high offer in market, it presents a continuous growing outlook. It is known also that such a meat has very particular characteristics due to its processing and because of the raw matter used in its production. The Ministry of Agriculture, Livestock and Food Supply (MAPA) sets the quality characteristics of MDCM concerning both microbiological and physic chemical profile, which have to be followed by the producers. In this way, five different MDCM brands, numerically identified (1 to 5) and formed by six samples from different batches each were evaluated for some parameters defined by MAPA. The microbiological analyses performed in meat matrix were Salmonella spp., Staphylococcus aureus and Clostridium perfringens, based on the acceptance criteria established by MAPA. It was also evaluated the following proximate analysis moisture, protein, fat, ash, peroxide index (PI). Judging the microbiological results, no brands were disapproved for C. perfringens, but two were disapproved in Salmonella spp. analysis once they exceeded the limit of acceptance for the test (c>2). The mean counting for S. aureus was 2,55 log UFC/g; 3,04 log UFC/g; 2,74 log UFC/g; 2,05 log UFC/g; and 3,05 log UFC/g for brands 1 to 5, respectively, which meant a 80% brands disapproval. The moisture mean values were in accordance with literature, showing variations of 61,0% to 68,8%. Based on MAPA physic chemical characteristics of quality, the mean protein values varied between 9,9% and 15,4% and two brands (2 and 5) were disapproved since they presented mean values under 12% ( 9,9% e 11,7%, respectively). The brands fat mean values varied from 14,5% to 28,7%, following the limits established by MAPA (max. 30%), although two batches of one brand were disapproved as they exceeded the limit of 30% established. The ash mean values varied from 0,7% to 1,1%. The peroxide index (IP) mean, established by MAPA in 1 mEq per kg of fat maximum, varied between 1,7 and 15,9 mEq/kg, causing a 100% brands disapproval. The disaccord of microbiological and proximate analysis results with Brazil standart regulations are indications that private and fiscal quality and self control programs should be improved. New studies should be performed to comprehend better and to get to know more about MDCM frozen stored oxidative behavior in relation to its raw matter quality and post production time.Desde o final da década de 1950, a carne mecanicamente separada (CMS) de ave tem sido utilizada pelas indústrias de carne, como matéria-prima para fabricação de produtos derivados. Tal prática tornou-se corrente e comum nos dias de hoje e, por questões produtivas, comportamentais e, até mesmo, pela grande oferta do produto em nosso país, apresenta perspectiva de crescimento contínuo. Sabe-se, também, que se trata de uma carne com características extremamente particulares, tanto devido ao seu processo de obtenção, quanto à matéria-prima utilizada para obtê-la. O Ministério da Agricultura Pecuária e Abastecimento (MAPA) estabelece as características de qualidade para a CMS, tanto em relação ao seu perfil microbiológico como físico-químico, que deve ser atendido pelos fabricantes com marcas disponíveis no mercado. Nesse sentido, foram colhidas cinco diferentes marcas comerciais de CMS de aves, identificadas numericamente de 1 a 5, cada uma delas composta por seis amostras de lotes distintos que foram avaliadas frente a alguns parâmetros estabelecidos pelo MAPA. Os critérios microbiológicos avaliados na matriz cárnea foram Salmonella spp., Staphylococcus aureus, e Clostridium perfringens, com base em critérios de aceitação estabelecidos pelo MAPA. Também foram avaliadas as seguintes características físico-químicas do produto: umidade, proteína, gordura, cinzas e índice de peróxido (IP). A partir do critério microbiológico de aceitação, dentre as marcas avaliadas, nenhuma foi reprovada para as determinações de C. perfringens, ao passo que duas marcas foram reprovadas nas determinações de Salmonella spp., por apresentarem número máximo de unidades amostrais acima do limite aceitável (c>2). A média das contagens de S. aureus foi de 2,55 log UFC/g; 3,04 log UFC/g; 2,74 log UFC/g; 2,05 log UFC/g; e 3,05 log UFC/g para as marcas de 1 a 5, respectivamente, resultando em reprovação de 80% das marcas. Nas avaliações físico-químicas, as médias dos valores de umidade estavam de acordo com dados da literatura, variando entre 61,0% e 68,8%. Frente às características físico-químicas estabelecidas pelo MAPA, as médias dos teores de proteína variaram de 9,9% a 15,4%, sendo que duas marcas (2 e 5) foram reprovadas com teores médios abaixo de 12% (9,9% e 11,7% respectivamente). A média do teor de gordura das marcas variou entre 14,5% e 28,7%, dentro dos limites estabelecidos pelo MAPA (máx. 30%), entretanto, em uma das marcas avaliadas, dois lotes foram reprovados com teor de lipídios maior que os 30% estabelecidos pela legislação. As médias dos teores de cinzas variaram de 0,7% a 1,1%. A média do índice de peróxido que o MAPA estabelece em no máximo 1 mEq por kg de gordura, variou entre 1,7 e 15,9 mEq/kg de gordura, resultando em reprovação de 100% das marcas analisadas. Os resultados das análises microbiológicas e físico-químicas, não se alinharam ao estabelecido nos padrões regulamentares, indicando que os programas de qualidade e de autocontrole, privados e fiscais, devem ser aperfeiçoados. Novos estudos devem ser realizados no sentido de expandir-se o conhecimento e melhor compreender o comportamento oxidativo da CMS estocada congelada em função da qualidade da matéria-prima e da vida de prateleira pós-produção.
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Bueno, Pedro Henrique Salgado. "Efeito da radiação gama e do tipo de embalagem sobre as características microbiológicas, físico-químicas e sensoriais de peito de frango refrigerado." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/ALOA-7C9QUG.
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Poultry meat is a frequent vehicle for food borne pathogens, which cause danger to its consumers and losses to the meat productive chain. The main objective of this study is to evaluate the effects of gamma irradiation (1.5 and 3.0kGy) in conventional-packed and vacuum-packed broiler breast. The samples were stored under refrigeration (4°C) for 30 days and different microbiological, physic-chemical and sensorial analyses were conducted. Gamma radiation was efficient in both dosages (1.5 and 3.0kGy) in eliminating Salmonella spp., reducing 3 logarithmic cycles of mesophilic aerobic bacteria, total and thermotolerant coliforms. Moulds and yeasts were very resistant to the radiation doses applied. There were no significant changes in meat quality and composition. Lipid oxidation was higher in samples irradiated with 3.0kGyCarnes de frango são transmissores constantes de toxicoinfecçoes alimentares, podendo causar danos à saúde do consumidor, assim como prejuízos à cadeia produtiva. O objetivo desse experimento foi analisar os efeitos da radiação gama em duas doses (1,5 e 3,0kGy) em peitos de frango embalados sob atmosfera convencional e à vácuo. As amostras, depois de embaladas e tratadas, foram estocadas sob refrigeração a 4ºC pelo prazo máximo de 30 dias. Foram realizadas análises microbiológicas, físico-químicas e sensoriais. A irradiação em ambas as doses, mostrou-se eficiente na eliminação de Salmonella spp., reduziu em aproximadamente 3,0 ciclos logarítmicos as contagens de mesófilos aeróbios estritos e facultativos viáveis, coliformes totais e coliformes termotolerantes. Bolores e leveduras mostraram-se bastante resistentes à radiação. Não houve diferença estatística para os parâmetros de perda de peso por gotejamento e evaporação durante a cocção, assim como para força máxima de ruptura e composição centesimal. A oxidação lipídica foi maior nas amostras irradiadas com 3,0kGy
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Machado, Michelle Moreira. "Efeito do congelamento e estocagem sobre a qualidade da carne bovina." Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/ALOA-7UZMMS.
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The effect of freezing and storage of beef (m. Longissimus dorsi) at -18 °C was evaluated at six pairs of m. Longissimus dorsi (twelve samples) from six castrated male cattle, with estimated age of two years identified as intermediaries age, and all samples with a pH final in the range of 5.4 to 5.9. The samples were prepared in different forms (ground, steak and whole) and kept for 30, 60 and 120 days under storage at -18 °C, result a total of 144 sub-samples. It was determined the proximate composition, pH, water holding capacity (WHC), loss of weight, shear force(WBSF) and quantification of lipid oxidation. There were no significant effect of time of storage or the forms on pH, proximate composition, loss of juices, and WBSF. The ground beef had higher (P <0.05) value of WHC, and time of storage has no effect on this parameter. The values of loss evaporation, during cooking, and lipid oxidation increased with time of storage, with higher cooking losses observed for the entire form and higher lipid oxidation for ground beefCom o objetivo de avaliar o efeito do congelamento e estocagem à -18 ºC de carne bovina (m. Longissimus dorsi), foram avaliados seis pares de contrafilé (doze amostras) provenientes de seis bovinos machos castrados, com idade estimada de dois anos, sendo identificados como animais intermediários, e todas as amostras apresentando um pH final na faixa de 5,4 a 5,9. As amostras foram preparadas em diferentes formas (moída, bife e porção de 1,5kg) e mantidas por 30, 60 e 120 dias sob estocagem a -18 ºC, sendo avaliado no total 144 sub-amostras. Foi determinada a composição centesimal, pH, capacidade de retenção de água, perdas de peso, maciez e quantificação da oxidação lipídica. Não houve efeito dos tempos de estocagem ou das formas para os parâmetros pH, composição centesimal, perda de suco e maciez. A carne moída apresentou maior (P<0,05) valor de capacidade de retenção de água, sendo que este parâmetro não sofreu efeito do tempo de estocagem. Os valores de perda de peso por evaporação, durante a cocção, e de oxidação lipídica aumentaram com o tempo de estocagem, sendo que as maiores perdas por cocção foram observadas para porção de 1,5kg e os maiores valores de oxidação lipídica para a carne moída
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Xavier, Daniel Rezende. "Efeitos do uso da irradiação e de antioxidantes na estabilidade da carne moída refrigerada." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/ALOA-8SMNMU.
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The main objective of this study is to evaluate the effects of gamma irradiation (4,5 kGy) and sodium eritorbate in conventional-packed ground beef. The samples were stored under refrigeration (2ºC) for 42 days and different physico-chemical, color and lipid oxidation (TBARS) analyses were conducted. There were no significant changes in meat composition during the 42 days of storage. The pH values were maintained in acceptable values for the association of irradiation and antioxidants. This association were also with statistic differences for prevent lipid oxidation in irradiated samples in 16 and 42 days of storage. Lipid oxidation was higher in samples irradiated with 4,5 kGy and antioxidants were efficient to maintain the levels of lipid oxidation in samples irradiated.Com o objetivo de avaliar os efeitos da irradiação gama e da adição de antioxidantes em carne moída bovina refrigerada (2ºC) foi realizado um experimento utilizando três peças de acém. Avaliou-se o efeito da dose de 4,5kGy de radiação gama, adição de antioxidante comercial (eritorbato de sódio) sobre a qualidade da carne in natura aos 0,2,4,8,16 e 42 dias de estocagem. Avaliou-se ainda o efeito da radiação gama e adição de antioxidantes sobre a medida de cor objetiva e oxidação lipídica, através do teste de TBARS, nas amostras frescas (dia 0) e posteriormente nas amostras armazenadas resfriadas aos 2,4,8,16 e 42 dias de estocagem. Dentre os resultados encontrados podemos destacar a estabilidade da composição centesimal da carne em todos os tratamentos realizados, a manutenção do pH em níveis aceitáveis com a associação de irradiação e antioxidante, e a caracterização da oxidação lipídica das amostras sobre os tratamentos realizados, encontrando-se diferença estatísticas entre as amostras irradiadas e não irradiadas em 16 e 42 dias de armazenagem. A oxidação lipídica foi maior nas amostras irradiadas e a adição de antioxidante foi eficiente em manter os níveis de oxidação lipídica das amostras irradiadas.
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Aguado, Carrera Gemma Patricia. "Síntesis e hidrogenación estereoselectiva de alfa,beta-deshidro-alfa-aminoácidos y alfa,beta-deshidro-alfa-péptidos ciclobutílicos. Aplicaciones sintéticas." Doctoral thesis, Universitat Autònoma de Barcelona, 2003. http://hdl.handle.net/10803/3156.
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Algunos aminoácidos ciclobutánicos de origen natural han presentado actividad biológica como antivíricos, analgésicos, antimicrobianos, antidepresivos y neurotróficos. Es por este motivo que en esta Tesis se prepararon diferentes a,b-deshidro-a-aminoácidos ciclobutílicos (DHAAs) ópticamente activos a partir de los precursores quirales a-pineno y (-)-verbenona. Dentro de estos DHAAs se sintetizaron pares de enantiómeros, DHAAs con la misma o inversa quiralidad, y con el doble enlace unido directamente al anillo de ciclobutano o a un metileno de distancia. La hidrogenación de estos compuestos, usando catalizadores aquirales (Pd/C y Wilkinson) y quirales ((S,S)-Chiraphos y Duphos), condujo a la síntesis de a-aminoácidos ciclobutílicos saturados, con elevadas estereoselectividades en algunos casos. Los APNs son pseudopéptidos capaces de transportar la información genética, vía las bases nucleicas, de igual manera que el ADN o el ARN. Ésta y otras propiedades, como por ejemplo la capacidad de actuar como agente antisense con elevada eficiencia, hacen posible que el oligómero de APN sea muy interesante en diferentes disciplinas: química, biología molecular y por supuesto en medicina. Así pues, en esta Tesis a partir de un a-aminoácido ciclobutílico saturado, se sintetizó el primer ácido péptidonucleico (APN) con un anillo de ciclobutano en su estructura. Se incorporó el monómero sintetizado en un decámero y se realizó un estudio de la estabilidad térmica en la hibridación del decámero con cadenas complementarias de ADN, ARN y APN. Los resultados de este estudio confirmaron que la incorporación del monómero en un oligómero no mejora ni empeora la afinidad por una cadena complementaria, en comparación con la afinidad que presenta un oligómero estándar de APN.
Por otra parte, a partir de un a,b-deshidro-a-aminoácido ciclobutílico se prepararon dos a,b-deshidro-a-péptidos ciclobutílicos ópticamente activos (dipéptidos) con buenos rendimientos. Uno de ellos contiene una unidad de glicina en su estructura, mientras que el otro contiene el aminoácido (S)-fenilalanina. Se realizó un estudio posterior de hidrogenación de estos compuestos, obteniéndose a-péptidos ciclobutílicos saturados con muy buenos excesos diastereoisoméricos, próximos al 100% en algunos casos. Se realizaron espectros de dicroismo circular de los a-péptidos, tanto insaturados como saturados, obteniéndose curvas con la misma tendencia que la de otros péptidos descritos en la bibliografía, los cuales se ha demostrado que poseen capacidad de ser inductores de giros b, debido a una conformación determinada, muy congelada, para estás moléculas.
Some natural cyclobutane amino acids have displayed activities as antiviral or antimicrobial agents, neurotropics and analgesics. Therefore, in this Thesis were prepared different chiral a,b-dehydro-a-cyclobutyl amino acids (DHAAs) from quiral precursors: a-pinene and (-)-verbenone. These DHAAs were synthesized in enantiomeric form, with the same and reverse chirality, and with the double bond directly attached to the cyclobutane ring or separated from the carbocycle by a methylene group. Some cyclobutyl saturated a-amino acids were produced with high stereoselectivity in some cases, in the hydrogenation of the DHAAs employing different achiral catalysts (Pd/C and Wilkinson) and chiral catalysts ((S,S)-Chiraphos and Duphos).
PNA is a pseudopeptide with the potential of carrying genetic information (via the nucleobase) code in a manner identical to DNA or RNA. This property and other, as for instance the ability of working like an antisense agent with high efficiency, make the molecule of PNA of significant interest in many disciplines of chemistry, molecular biology and of course in medicine. Therefore, in this Thesis, from a saturated cyclobutyl amino acid, we synthesized the first peptide nucleic acid (PNA) with a cyclobutane ring. The monomer was incorporated in a decamer and it was hybridized to complementary DNA, RNA and PNA. We studied the thermal stability (Tm) of the hybrids. The results of this researches confirmed that the incorporation of the cyclobutanyl PNA monomer in an oligomer doesn't change the affinity to a complementary oligonucleotide, if we compare it with the affinity that displays a standard PNA oligomer.
On the other hand, some chiral a,b-dehydro-a-cyclobutyl peptides (dipeptides) were synthesized, in high yields, from one DHAA. One with the amino acid glycine, and the other one with a (S)-phenylalanine. The hydrogenation of these compounds afforded cyclobutyl saturated a-peptides with high de (~100% in some cases). The CD spectra of the a-peptides, unsaturated and saturated, showed the same tendency as other peptides with the capacity of being b-turn inducers, due to a fixed conformation for these.
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MAYET, JEAN FRANCOIS. "Responsabilité et réparation dans les établissements de santé." Toulouse 1, 1998. http://www.theses.fr/1998TOU10042.
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Depuis des annees la responsabilite en matiere medicale fait l'objet de nombreuses discussions. Face a la difficile indemnisation des victimes de dommages medicaux, le maintien du systeme actuel de responsabilite est regulierement remis en cause. Faut-il pour autant modifier le fondement de la responsabilite et condamner les differents acteurs medicaux en l'absence meme de faute, ou bien mettre en place un mecanisme de reparation specifique ? cette delicate question se pose avec encore plus d'acuite aujourd'hui. La jurisprudence en effet n'hesite pas a elargir le champ de la responsabilite en y incluant les etablissements de sante, la complexite de l'organisation hospitaliere vient perturber la reflexion, au-dela de leur propre activite, les cliniques privees doivent-elles etre responsables de celle des praticiens ? peuvent-elles etre a l'origine d'un contrat de soins medicaux ? par ailleurs, l'absence de responsabilite des medecins publics hospitaliers ne cree-t-elle pas des inegalites de traitements avec leurs confreres du secteur prive, et entre les malades selon le lieu d'hospitalisation ? l'evolution de la responsabilite au cours de ce siecle a ete suffisamment importante pour ne plus laisser l'activite medicale de cote. L'intervention du legislateur semble donc a present ineluctable afin de repondre aux attentes de chacunFor years, responsability in medical matter has been the theme of many discussions, in front of the difficulty of getting compensation for medical damages, keeping up the actual responsabili+y scheme is a regular debatable point, but has the basis of responsability to be modified for all that, and have the different medical actors to be condemned without any fault ? or, has a specific compensation mechanism to be established ? this critical question has been asked today with more acuteness than never. The jurisprudence, indeed, doesn't hesitate to widen the range of responsability, including the health institutions. The complexity of hospital organization disturbs the analysis. Beyond their own activity, have private clinics to be responsible of the practitioner's one ? can they be in the begining of a medical care contract ? by another way doesn't the lack of responsabili+y of public hospital practitioners create a disparity of +rea+men+ between patients according to their hospitalization place ? the evolution of responsability during this century has been sufficienly significant to ignore no more the medical sector ! the intervention of the legislator seems now to be ineluctable in order to respond to everyone's expectations
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Prudil, Pavel. "Alfa monitor." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2010. http://www.nusl.cz/ntk/nusl-218645.
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This master‘s thesis presents the problems of EEG bio-feedback and its application for relaxing a person. It deals with the requirements of the sensing electrode and the biological signal amplifiers. The main substance of my thesis is the proposal of Alpha monitor, a device that uses the electrical activity of alpha brain waves for the realization of biological EEG feedback. The device concept takes into consideration the requirements of users’ security and also characteristics of alpha activity, which define the requirements for signal processing circuits and for propositions of the aural transducer. This master‘s thesis analyses given submission, proposes particular circuits, presents the overall electrical diagram and the list of components. The overall electrical diagram and single circuits are drawn within the EAGLE 5.7.0.
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Svobodová, Eva. "Alfa monitor." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2014. http://www.nusl.cz/ntk/nusl-220866.
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The master´s thesis presents the problems of EEG biofeedback and its application to relax people. The first part discusses the properties of EEG signal , the requirements of the standard EEG and also distribusion signal into different frequency bands. The main essence of the work is the design and realization of Alfa Monitor – a device for relaxation , that for implamanting EEG biofeedback uses acoustic form and sensing of electrical activity of brain in the region of alpha waves. The second half of the work is t focused on circuit design, using integrated circuits with component values of relevant calculations . Further, it analyzes the practical implementation of alfa monitor. The last chapter is devoted to the testing the functionality of this device.
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Zadow, Charlotte von. "Linea alba unguis (Zona alba) - zur weissen Linie des Pferdehufes /." Berlin : Mbv, 2008. http://d-nb.info/989679675/04.
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Haglund, Erik, and Fredrik Johansson. "Jakten på Alfa." Thesis, Halmstad University, School of Business and Engineering (SET), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-1535.
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Genom en kvantitativ studie av 60 aktier på Stockholmsbörsen har följande fråga besvarats. Hur kan en investerare utnyttja historisk information för att nå riskjusterad överavkastning? En teknisk analys för att testa den svaga formen av informationseffektivitet genomfördes. Aktiernas faktiska avkastning jämfördes med den förväntade enligt CAPM, och de alfavärden som observerades testades genom variansanalys. Resultaten från studien visade att de undersöka aktierna har alfavärden som är signifikant skilda från noll, när endast skillnaden studerades. Sett till längre perioder, såsom tre och tolv månader, tenderar dock de genomsnittliga alfavärdena att jämnas ut, varför endast ett fåtal har kunnat säkerställas statistiskt. Slutsatsen blir därför att den svenska aktiemarknaden åtminstone är halvstarkt effektiv, då historien inte innehåller information om framtida prestation.
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Hudson, C. E. "Photoionization of AlII." Thesis, Queen's University Belfast, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268922.
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Kašpar, Blahoslav. "Monitor alfa aktivity." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219517.
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This work deals with problems of EEG biofeedback and possibilities of its use in therapy. The method of EEG biofeedback helps patients to achieve the state of relaxation. It is a noninvasive treatment modality. The paper also discussed the requirements for each component unit. The main point of a design and construction of Alpha activity monitor, a device implementing EEG biofeedback focused on sensing electrical activity of the brain, specifically alpha waves. Alpha activity is specific and their parameters are taken into account when selecting components and construction equipment. Custom feedback is then for the appearance of alpha activity mediated by the headphones in acoustic form. The work also includes design of electrical circuits and electrical diagram of the overall apparatus including a list of used parts. Electrical diagrams are formed in the EAGLE 6.1.0.
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Aidoud-Lounis, Fatiha. "Le complexe A alfa-armoise-sparte (Stipa tenacissima L. , Artemisia herba-alba asso, Lygeum spartum L. ) des steppes arides d'Algérie : structure et dynamique des communautés végétales." Aix-Marseille 3, 1997. http://www.theses.fr/1997AIX30054.
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La vegetation des steppes arides est soumise a l'aridite, l'irregularite du climat et surtout a une forte pression anthropique. L'influence de ce dernier facteur se manifeste deja a une echelle globale a travers l'analyse des formes biologiques determinant les structures de vegetation. L'analyse ecologique de ces structures montre les effets prioritaires de la degradation d'origine anthropique pour le cortege des vivaces et du voile eolien pour celui des therophytes. L'approche synusiale syntaxonomique, des groupements du complexe steppique prenant en compte leur structure en mosaique, aboutit a un double sunsysteme : les lygeo-stipetea rivas-martinez, 1977 et lygeo-stipetalia br. -bl. & de bolos (1954) 1957 em. Pour les vivaces et les stipo-brachypodieta (br. -bl. , 1947) brullo, 1985 nom. Nov. Et koelerio-schismetalia ord. Nov. Pour les therophytes. Les analyses dynamiques (synchronique et diachronique) soulignent le lien etroit entre le deficit hydrique, la pression anthropique et les phenomenes d'erosion (deflation vs apport) dont les effets synergiques determinent les deux principales trajectoires regressives des systemes ecologiques et de la vegetation steppique.
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Wrigstad, Tobias. "Ownership-Based Alias Managemant." Doctoral thesis, Stockholm : KTH Information and Communication Technology, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3956.
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Imamovic, Jasmin. "När Alfa förvärvade Beta." Thesis, Högskolan i Borås, Institutionen Handels- och IT-högskolan, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-16711.
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Den här kandidatuppsatsen behandlar företagsförvärv i sin helhet, med integrationsfasen i fokus.Ett företag som vill vara konkurrenskraftig på dagens dynamiska och intensiva marknader måste överväga företagsförvärv som en del av sin långsiktiga strategiska planering för att kunna uppnå sina mål.Att växa genom företagsförvärv ger många fördelar bl. a. snabbare tillväxthastighet jämfört med enbart organisk tillväxt, den egna organisationen växer och konkurrenternas marknadsandelar krymper.Det är dock inte oproblematiskt att använda sig av företagsförvärv som tillväxtstrategi.Många studier visar att risken är stor att ett företagsförvärv inte lever upp till förväntade resultat som förvärvsorganisation hade i samband med uppköpet.Företagsförvärv omfattar många komplexa delprocesser som kräver en genomtänkt planering och uppföljning.Dock är det en del i förvärvsprocessen som enligt många teoretiker spelar avgörande roll för förvärvets framgång. Den delen av förvärvsprocessen kallas för integrationsfasen och djupet i den här uppsatsen kommer att handla om den fysiska integreringen i samband att Alfa köpte upp Beta.Syftet med den här uppsatsen är att förmedla en ökad förståelse för förvärvsprocessen samt ge en överskådlig bild för hur en förvärvsprocess lämpas i teorin och praktik. Det skall även vara ett verktyg för företaget Alfa vid eventuella framtida företagsförvärv.Studie är av kvalitativ karaktär och byggs på interaktion mellan litteraturstudier inom ämnet företagsförvärv och empirisk data som hämtades in huvudsakligen med hjälp av intervjuer med korrespondenter som jobbar eller har jobbat inom Alfas organisation. I uppbyggnaden av den empiriska berättelse använde jag mig även av egna observationer på Alfas anställda då jag som uppsatsens författare var anställd inom organisationen.Min uppsats kan varken utgå ifrån ren deduktiv, induktiv eller abduktiv vetenskapligansats, därför blev min undersökningsmetod aktionsforskning som förespråkar att forskaren är anställde på undersökningsobjektet på grund av bättre access till nödvändig data.Då uppsatsen syfte är att öka förståelse för förvärvsprocessen utgår jag ifrån ett hermeneutiskt förhållningssätt.Efter utförd analys på det samlade empiriska materialet med hjälp av den etablerade forskningen inom ämnet företagsförvärv kom jag fram till samma slutsats som Alfas företagsledning.Alfas förvärv av Beta levde inte upp till det önskade resultatet som Alfas ledning och ägare hoppades på när de genomförde transaktionen.Jag är av den uppfattningen att önskade resultat uteblev på grund av bristfällig kommunikation så väl internt som externt, vissa förhastade och ogenomtänkta beslut från Alfas ledning, underskattning av kulturella skillnader och sist men inte minst avsaknad av integrationsmanager.Program: Kandidatutbildning i företagsekonomi
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Zadow, Charlotte von [Verfasser]. "Linea alba unguis (Zona alba) - zur weißen Linie des Pferdehufes / Charlotte von Zadow." Berlin : Freie Universität Berlin, 2008. http://d-nb.info/1023049996/34.
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Laurel, L. "Variation in capture and wild populations of the barn owl Tyto alba alba." Thesis, University of Edinburgh, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.653703.
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Barn Owls Tyto alba alba have undergone a population decline in Britain since the 1930s; the release of captive-bred barn owls has been a popular response to the perceived problem. A loss of genetic variability is predicted from available demographic data for both captive and wild barn owl populations, this study was initiated to assess the suitability of protein electrophoresis and quantitative variation for monitoring genetic variation in barn owl populations. A total of 304 samples were obtained over three years, from barn owls from two wild and three captive populations in Britain. Quantitative traits were assessed for their suitability for heritability analysis (measurement error, intercorrelations of traits, sexual dimorphism and population differentiation); fluctuating asymmetry (FA), and two possible predictors of body condition based on tarsus and weight data, and a blood parameter (packed cell volume) are also discussed. Heritability in one wild population were calculated by parent offspring regressions and analysis of variance of sibling data. Heritability estimates were characterised by large standard errors; the problems of estimating heritability in wild populations are discussed. Heritability of tarsus length of mean offspring/mid-parent regression (±S.E) was 0.64 ±0.27; the genetic coefficient of variation was 2.40%. It is argued that the genetic coefficient of variation, rather than heritability, is the appropriate statistic for inter-population comparisons of heritable quantitative variation; the barn owl population had a level of genetic variation for tarsus length comparable to that demonstrated in other avian studies. The merits of isozyme and quantitative genetic approaches to monitoring genetic variation are discussed.
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Baba-Ali, Mehdi. "Système de nomination hiérarchique pour les systèmes paramétriques." Poitiers, 2010. http://theses.edel.univ-poitiers.fr/theses/2010/Baba-Ali-Mehdi/2010-Baba-Ali-Mehdi-These.pdf.
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Au début des années 60, les systèmes de modélisation géométrique sont apparus. D'abord cantonnés à de simples outils d'esquisse, ils ont su, au fil des années, se doter de modèles géométriques plus élaborés (tant sur l'aspect plongement avec les courbes et surfaces paramétriques ou les surfaces implicites que sur l'aspect topologie avec des modèles à base combinatoire) et des informations additionnelles permettant la gestion de divers aspects du processus de modélisation industrielle. Les modèles géométriques permettent de décrire des formes géométriques en s'appuyant sur des structures topologiques très variées. Cependant, les opérations de modèlisation menant à ces descriptions ne prennent pas en compte les intentions de l'utilisateur du fait qu'elles n'utilisent ni son langage, ni ses gestes et moins encore son expérience métier. C'est pourquoi on a associé aux modèles géométriques initiaux des informations supplémentaires connues sous le terme de caractéristiques (features) et en particulier les caractéristiques de formes (rainure, bossage, arrondi, etc. ). Si la description par caractéristiques (géométrie, paramètres des opérations de modèlisation de haut niveau, contraintes) est enregistrée pour être exploitée dans la perspective d'être réutilisée (réévaluée en faisant varier les paramètres), on parle alors de modèlisation paramétrique basée historique (ou history-based en terminologie anglo-saxonne). Aussi, un modèle paramétrique, de par sa structure duale, pose le problème de la nomination persistante qui dérive de la nécessité de maintenir un lien entre la géométrie et sa représentation implicite en termes de script de modèlisation. Dans ce contexte, plusieurs solutions ont été proposées. Chacune d'entre elles s'efforce de caractériser (de façon unique et non ambigüe) puis apparier (c’est-à-dire mettre en correspondance) les entités des modèles initial et réévalué. Dans un environnement 3D extrêmement variant, les approches actuelles s'appuient sur des éléments invariants -les faces- pour mettre en oeuvre différents procédés de caractérisation. En les étudiant de plus près, on constate d'une part que ces procédés ne proposent pas de caractérisation homogène pour les entités ou les agrégats d'entités de dimension supèrieure ou égale à 3. Cela limite la généralisation en toute dimension des mécanismes de nomination (caractérisation et appariement). D'autre part, ces méthodes pêchent de façon plus ou moins importante lorsqu'il s'agit de manipuler des objets dans un contexte non-planaire. Dans ce mémoire, nous nous intéressons à la nomination persistante et homogène des entités de toute dimension (sommets, arêtes, agrégats d'arêtes, faces, agrégats de faces (« coques »), volumes, agrégats de volumes, etc. ) et celles résultant de l'interaction d'objets non-planaires. Pour ce faire, nous proposons une plate-forme hiérarchique mettant en scène, par des relations d'agrégations, des entités de n'importe quelle dimension. Notre idée est alors de commencer par nommer, c’est-à-dire caractériser et apparier, les entités de la plus petite dimension exploitable : les arêtes. La gestion des noms au niveau des arêtes s'effectue principalement via un graphe traçant l'évolution de ces entités au cours du processus de modèlisation paramétrique. Ensuite, nous faisons en sorte d'exploiter l'appariement calculé entre ces arêtes, en parcourant la structure hiérarchique et agrègative, afin d'en déduire celui entre les entités de dimension supèrieure. Notre solution est implantée sur un noyau géométrique basé sur le modèle des cartes généraliséesNowadays, many parametric systems support history-based , constraint-based and feature-based modelling. Unfortunately, most systems fail during the reevaluation phase when various kind of topological changes occur. This issue is known as “persistent naming”. It refers to the problem of identifying entities in an initial parametric model and matching them in the reevaluated model. Several solutions have been proposed to solve this problem, but they remain insufficient. In this thesis, we focus on the persistent and homogeneous naming of entities in any dimension (vertices, edges, aggregates of edges, faces; aggregates of faces (“shells”), volumes, aggregates of volumes, etc) and entities resulting from the intersection of non-planar objects. To do that, we propose a hierarchical platform which gathers, by relations of aggregations, entities of any dimension. Our idea is then, to begin by naming (i. E. ) to characterize and to map) the smaller usable entities: the edges. The management of names of the edges is mainly carried out by a graph tracing the evolution of these entities during the process of parametric modelling. Then, we used the computed matching between these edges by exploiting the hierarchical and aggregative structure of the topological model, in order to deduce the matching between the entities of higher dimension. Our solution is implemented on a geometric kerned based on the generalized maps model
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Hanna, Laurel. "Variation in captive and wild populations of the barn owl Tyto alba alba (Scopoli)." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/14986.
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Estivill, Domènech Carla. "Preparació enantioselectiva i estructura de l'[alfa], [alfa]'-bis(trifluorometil)-9,10-antracendimetanol (abte), l'[alfa], [alfa]'-bis(trifluorometil)-9,10-antracendimetanamina (ABTA) i aproximació a l'[alfa]-trifluorometil-9-[10-(2,2,2-trifluoroetanamino)]antracenmetanol (ABTEA). RMN: utilització com a CSAs i estudi dels complexos bidentats." Doctoral thesis, Universitat Autònoma de Barcelona, 2006. http://hdl.handle.net/10803/3245.
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A la present tesi doctoral es desenvolupen nous estudis sobre agents de solvatació quiral (CSA) difuncionals. Els CSAs tenen la capacitat d'interaccionar de forma diferencial amb cada un dels enantiòmers d'una mescla d'un substrat quiral, mitjançant la formació d'enllaços no covalents, és a dir, de tipus àcid-base, ponts d'hidrògen, dipolars,... formant complexes d'associació diastereomèrics. Aquest reconeixement quiral produeix un diferent entorn químic i magnètic dels enantiòmers, el que per RMN es podrà observar en una anisocronia dels seus senyals, principalment de protó. Aquesta diferència dels desplaçaments químics ens permetrà determinar la composició de la mescla. Ja que l'observació dels senyals és una mitja d'un sistema dinàmic entre els elements lliures i complexats, la separació dels senyals dependrà tant de la termodinàmica de l'associació com de les característiques estructurals dels complexes.En el nostre grup d'investigació es va abordar la síntesi de CSAs difuncionals. En el primer cas que ens ocupa a la present tesi doctoral, l'?,?'-bis(trifluorometil)-9,10-antracendimetanol (ABTE) va aportar una gran capacitat enantiodiferenciadora. Els estudis per RMN ens permeteren atribuir aquests resultats en la capacitat que té el confórmer Cisoide de l'ABTE en generar complexes bidentats amb els substrats quirals, en els que la major proximitat del CSA a cada una dels enantiòmers del substrat, provoca una major diferenciació en l'entorn magnètic.
A la present tesi doctoral s'abordà la síntesi estereoselectiva de l'ABTE. La reducció tipus CBS del 9,10-bis(trifluoroacetil)antracè ens permeté obtenir el CSA desitjat en un 65% de rendiment i amb una proporció estereomèrica de RR/RS/SS= 89:11:0. Aquesta ruta es va dur a escala més gran, per tal de fer la seva fabricació per a la seva comercialització (ACRÔS).
Per RMN també s'estudien les associacions entre l'ABTE i l'1,2-benzendimetanol i l'1,3-benzendimetanol, per evidenciar l'existència dels complexes bidentats. S'observen les variacions dels senyals de protó del CSA, també es determinen les estequiometries dels complexos i les seves constants de formació. L'estudi es completa amb un estudi teòric per mecànica molecular. Amb tots els resultats es pot concloure que el CSA forma un complex bidentat amb l'1,2-benzendimetanol i també amb l'1,3-benzendimetanol, però amb aquest últim no de forma exclusiva sinó que també existeixen associacions monodentades.
També s'estudien les diferències estructurals i d'estabilitat de la interacció entre l'ABTE i l'1-aminoindà i l'1-amino-2-indanol. L'existència de l'associació bidentada s'evidencià amb la major variació dels desplaçaments químics de cada un dels enantiòmers del substrat en relació a la que es va obtenir en la solvatació amb el CSA homòleg monofuncional. Amb el primer substrat es va poder atribuir en un augment de l'estabilitat de l'associació, degut, segurament a una disminució de l'entropia. En canvi, amb l'1-amino-2-indanol no es van apreciar diferències en l'estabilitat, amb el que podem atribuir una major variació dels desplaçaments químics a efectes estructurals de la complexació, principalment en una associació bidentada més íntima.
A la segona part de la tesi es desenvolupa la síntesi estereoselectiva de l'?,?'-bis(trifluorometil)-9,10-antracendimetanamina (ABTA), que s'obté per la doble trifluorometilació de la sulfinimina quiral derivada de la condensació del 9,10-antracendimetanol amb la sulfinamida de Ellman, amb un rendiment global d'ABTA del 57% i de forma enantiopura. També es descriuen les síntesis de la 2,2,2-trifluoro-1-(9-antril)etilamina, la 1-(9-antril)etilamina i l'aproximació de l'?-trifluorometil-9-[10-(2,2,2-trifluoroetanamino)]antracenmetanol (ABTEA).
Es fan diversos estudis de solvatació mitjançant RMN, del nou CSA difuncional ABTA. En ells es va observar la separació de les bandes dels protons dels enantiòmers en afegir un elevat nombre d'equivalents de CSA, fins a 15, i l'estudi termodinàmic, que també es va realitzar per RMN, ens va donar constants d'associació molt baixes. Probablement, aquests resultats es deuen a la poca basicitat del grup amino, que no afavoreix la formació de ponts d'hidrògen.
In the current thesis new studies about difunctional chiral solvating agents (CSA) are developed. CSAs have the ability to interact differentially with each of the enantiomers of a chiral substrate, through non covalent bonds, like acid-base interactions, hydrogen bonds, dipolar interactions.giving diastereomeric associative complexes. This chiral recognition produces distinct chemical and magnetic properties to each enantiomer, that will be observed, in RMN, as an anisocrony of its signals, mainly the proton signals. This chemical shift difference will allow us to determine the composition of the mixture. Since the observed chemical shifts are an average of a dynamic system where elements are free or complexate, the chemical shift variation will depend on the thermodynamic of the association and either on the structural properties.
In our research group, the synthesis of difunctional CSAs has been developed. The first case which we're dealing with at the current thesis, is the ?,?'-bis(trifluoromethyl)-9,10-anthracenedimethanol (ABTE), that showed, in last studies, an excellent chiral recognition capacity. The NMR studies allowed us to conclude that this attribute is due to the capability of the Cisoid conformer of the ABTE to give bidentate complexes with the chiral substrates, where the greater proximity of the CSA to each one of the enantiomers of the substrate, induces a greater differentiation of their magnetic fields.
In the current thesis, the stereoselective synthesis of ABTE has been developed. The CBS reduction of 9,10-bis(trifluoroacetyl)anthracene allowed us to obtain the desired CSA in a 65% yield with an stereomeric ratio of RR/RS/SS=89:11:0. This reaction has been scaled up for the manufacture and commercialization of the product (ACRÔS).
With the NMR, we have been studied the association between ABTE and 1,2-benzenedimethanol and 1,3-benzenedimethanol, to demonstrate the existence of the bidentate complexes. We observed the chemical shift of the proton signals of the CSA, and we determined the stequiometry of the complexes and their binding constant. The study is completed with a theoretical estimation by molecular mechanics. With all the results, we could conclude that the CSA generates a bidentate complex with 1,2-benzenedimethanol and also with 1,3-benzenedimethanol, but not as an exclusive form with the last one, which would be in equilibrium with monodentate associations.
There has been studied, also, the structural and thermodynamic differences of the interactions of the ABTE with 1-aminoindane and 1-amino-2-indanole. The greater difference of the chemical shifts between enantiomers of each substrate compared to the results obtained when using the comparable monofunctional CSA, gives us evidences of the existence of the bidentate association. With several NMR experiments, we could attribute the greater chiral recognition with the first substrate to a more stable association, due to probably lower entropy. On the other hand, the association with the second substrate didn't improve because of a more stable complex, but for the structural properties, mainly in a more close bidentate association.
At the second part of the thesis, the stereoselective synthesis of ?,?'-bis(trifluoromethyl)-9,10-antracenedimethanamine (ABTA) is developed. It consists in a double stereoselective trifluoromethylation of the chiral sulfinimine derived from the condensation of 9,10-anthracendimethanol with the Ellman sulfinamide, with a 56% global yield of the ABTA in its enantiopure form. There are also described the synthesis of 2,2,2-trifluoro-1-(anthryl)ethylamine, 1-(9-anthryl)-ethylamine and the approach to the ?-trifluoromethyl-9-[10-(2,2,2-trifluoroethanamino)]anthracenemethanol (ABTEA).
The chiral recognition capability of the new difunctional CSA, ABTA, is studied with several chiral substrates. The registered NMR experiments showed us a generally low capacity, observing the differentiation of the chemical shifts of the enantiomers after adding great amounts of CSA. The thermodynamic study could be done also with the NMR, and it gave us very low binding constants of the diastereomeric complexes. These results could come, probably, of the low basicity of the amino group, that wouldn't favour the formation of hydrogen bonds.
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Nelson, Matthew N. "Genetic analysis of Sinapis alba." Thesis, University of East Anglia, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327544.
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Grandazzi, Alexandre. "Alba-Longa histoire d'une légende." Lille 3 : ANRT, 1990. http://catalogue.bnf.fr/ark:/12148/cb37598363q.
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Oliveira, Marli Rodrigues Lunezo Guimarães de. "Alexitimia na algia pelvica cronica." [s.n.], 2001. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310752.
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Orientador : Maria Adelia Jorge MacFaddenTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas
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Resumo: Alexitimia, termo criado por Sifneos em 1973, refere-se a um conceito clínico-descritivo importante para a compreensão dos processos de somatização decorrentes de dificuldades afetivo-emocionais. A relação entre a qualidade da expressão emocional e algia pélvica crônica tem sido pouco estudada, sendo este o objetivo desta pesquisa que teve um enfoque quantitativo ¿ para o total de sujeitos e uma abordagem qualitativa para uma amostra aleatória de 8 sujeitos de cada grupo. Para a abordagem quantitativa, dois grupos de mulheres, cada um com 80 sujeitos, um grupo portador de algia pélvica crônica, e o outro não portador, foram investigadas quanto à presença de alexitimia, utilizando-se o instrumento Toronto Alexitimia Scale (TAS-20). Para a abordagem qualitativa, 8 mulheres de cada grupo, escolhidas aleatoriamente, responderam a uma entrevista clínica semi-estruturada para investigação de dados psicossociais. Os resultados mostraram que as mulheres do grupo de dor pélvica crônica tinham menor escolaridade, menor renda e maior número de filhos. O índice no TAS-20 deste grupo foi maior, especialmente no subgrupo de mulheres com dor e que tinham união conjugal. Foi confirmada a relação entre dor e maior índice para alexitimia. A análise qualitativa evidenciou diferenças na qualidade de vida entre os grupos, relativas às dificuldade de aprendizagem e aos planos para o futuro. O grupo com dor apresentou, com maior freqüência dificuldades para aprender a ler e escrever e expectativas mais concretas, objetivas e coletivas. O grupo não portador relatou expectativas mais abstratas, individuais e subjetivas. Este estudo confirmou pesquisas anteriores que encontraram associação entre alexitimia e dor crônica, baixa escolaridade e baixa renda
Abstract: The term, Alexithymia was coined by Sifneos, in 1973, to describe a clinical concept that helps to understand the somatization resulting from affective-emotional difficulties. The main theme of this study is the relationship between quality of emotional expression and chronic pelvic pain. It is a subject that has not received much attention and therefore this study has a quantitative focus related to the total number of participants and a qualitative approach in relation to a random sample selection of 8 individuals from each group. The quantitative approach involved two groups with 80 women in each. One group consisted of women with chronic pelvic pain and the other, a group of women with no pain. The Toronto Alexithymia Scale (TAS-20) was used to investigate the presence of Alexithymia. In the case of the qualitative approach, 8 women who were randomly selected from each group participated in a semi-structured clinical interview that investigated psychosocial data. The results demonstrated that the group of women with chronic pelvic pain had a poor educational level, poor income and a greater number of children. The TAS-20 index for this group was higher, especially in the subgroup of women with pain and in conjugal unions. The qualitative evidence revealed very few differences in the quality of life of the various groups. These differences were related to learning difficulties and future plans. The group of women who did have chronic pelvic pain demonstrated a higher frequency of difficulty in learning to read and write as well as expectations that were more objective, concrete and collective while the group with pain reported expectations individualistic, subjective and abstract. This study confirmed previous findings that related alexithymia and chronic pain with poor educational level and income
Doutorado
Saude Mental
Doutor em Ciências Médicas
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Almeida, Linoberg Barbosa de. "Sistema Mundial, Mercosul e Alca." Florianópolis, SC, 2004. http://repositorio.ufsc.br/xmlui/handle/123456789/88062.
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-graduação em Sociologia PolíticaMade available in DSpace on 2012-10-22T05:14:48Z (GMT). No. of bitstreams: 0
O objetivo principal deste trabalho é analisar como se dá a continuidade da consolidação do Mercosul, a ampliação das relações com a União Européia e o momento de formação da ALCA (Área de Livre-Comércio das Américas) no conjunto da política externa brasileira. Isto é, como desenvolve-se o processo decisório baseado em possibilidades de integração a uma economia globalizada que contempla basicamente econômicos deixando em segundo plano aspectos como soberania e legitimidade. A partir do cenário em questão e de conceitos como hegemonia, sistema-mundo e imperialismo, discutimos a possibilidade para que se construa uma nova composição de forças que possibilitem uma outra orientação política fruto da vontade coletiva resultando lutas sociais que gerem ações políticas diferentes das presentes atualmente nos discursos do governo brasileiro. Para tanto, encontra-se aqui: uma análise das transformações do sistema mundial e seus elementos determinantes como riqueza, Neoliberalismo, globalização e o papel de algumas instituições internacionais e dos Estados Unidos; alguns aspectos sobre as teorias de integração; a importância de uma projeto de Mercosul; e algumas questões relevantes sobre os governos Cardoso e Lula no constante avanço e retrocesso da política externa brasileira sujeita as vontades do mercado.
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Grandazzi, Alexandre. "Alba Longa, histoire d'une légende." Paris 4, 1986. http://www.theses.fr/1986PA040323.
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Il s'agit de l'étude de la légende d'Albe la Longue, sous un triple point de vue philologique, archéologique et historique. Après une analyse des caractéristiques de la géographie du Latium, on passe à la définition des différentes phases chronologiques de la civilisation latiale et à la discussion des paramètres permettant d'établir une typologie du matériel archéologique. Le système adopté est celui de Müller-Karpe et Peroni. Les témoignages matériels de la civilisation latiale (de la fin de l'âge du bronze jusqu'à l'ère archaïque)dans les Colli Albani : inventaire et interprétation. Le problème de localisation d'Albe la Longue. Ce que nous apprennent les Féries latines sur le plus ancien nomen Latinum. Examen des traditions relatives au nom d'Albe, qui montre la mise en place progressive d'une version canonique des Primordia Romana. Enfin, la légende des colonies albaines apparaît comme la clef de voûte de l'histoire du Latium archaïqueThis is a study of the legend of Alba la Longue under a triple point of view, philological, archeological and historic. After an analysis of the caracteristics of the geography of the Latium, we study the definition of the differents chronological phasis of the latial civilization and the parameters which permet to establish a typology of the archeological material. .
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Fredriksson, de Rond Casper. "Alfa-beta kvoten i prostatacancer." Thesis, Uppsala universitet, Tillämpad matematik och statistik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-420610.
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Rojas, García Roxana Isabel. "Uso catalítico de nanomicelas en la síntesis de alfa-sulfonilcetonas a partir de alfa-bromocetonas." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2017. http://hdl.handle.net/20.500.11799/67683.
Full textAbstract:
Las sulfonas pertenecen a una clase conocida de compuestos, utilizados en la síntesis orgánica, como agentes antimicrobianos y antifúngicos, entre otros.
De los derivados de las sulfonas, se centra la atención a las α-sulfonilcetonas, las cuales llevan la función carbonilo en la posición β, con respecto al grupo sulfonilo, dichos productos son intermediarios versátiles en síntesis orgánica.
En el presente trabajo de investigación se describe una metodología efectiva, económica, bajo condiciones de reacción sencillas y sobre todo cuidando el ambiente para la síntesis de α-sulfonilcetonas a partir de α-bromocetonas, haciendo uso de nanomicelas con el fin de generar un método ecológico, reduciendo considerablemente la generación de residuos orgánicos difíciles de desechar.
Una vez estandarizado el método se realizaron ensayos utilizando las siguientes α-bromocetonas como materia prima, 2-Bromo-4´-nitroacetofenona, 2-Bromo-4´-cloroacetofenona, 2-Bromoacetofenona, 2-Bromo-1´-bromoacetofenona, 2-Bromo-4´-metilacetofenona, 1-(1-Bencil-5-metil-1H-1,2,3-Triazol 4-1) 2-Bromoetanona, de las cuales los resultados fueron positivos, se obtuvo el producto de interés con rendimientos entre 71 y 88%. Así mismo se realizó una prueba control para determinar que las reacciones se llevan a cabo con el uso de nanomicelas, se observó que la reacción no se favorece al usar agua en sustitución de nanomicelas.
Los productos obtenidos fueron identificados a través de espectroscopia infrarroja y Resonancia Magnética Nuclear de 1H y 13C,UAEMex proyecto No. 3512/2013
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Sólorzano, Cháves Eddyn Gabriel. "Avaliação de cultivos de Kappaphycus alvarezii em diferentes condições climáticas e hidrólise enzimática do resíduo gerado pós-processamento de Carragena /." Araraquara, 2017. http://hdl.handle.net/11449/152614.
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Orientador: Fernando MasarinBanca: Banca: Kelly Johana Dussan Medina
Banca: Samuel Conceição de Oliveira
Resumo: Kappaphycus alvarezii é uma macroalga vermelha utilizada principalmente para produção industrial de hidrocolóides (principalmente carragena). O cultivo de K. alvarezii foi estabelecido como uma atividade econômica importante em mais de 20 países. Os principais componentes da biomassa de K. alvarezii são carboidratos. O processamento de carragena a partir de K. alvarezii promove a formação de um resíduo rico em glucana. Objetivo: Avaliar o desenvolvimento de cultivos de K. alvarezii em diferentes condições climáticas e averiguar o efeito da hidrólise enzimática sobre os resíduos obtidos pós-processamento de carragena. Métodos: A parte experimental envolveu o cultivo de 4 cepas de K. alvarezii ao longo de um ano no oceano atlântico em Ubatuba-SP. A partir dos dados dos cultivos foram calculadas as velocidades de crescimento e produtividades. Cultivos selecionados com base nos dados de produtividade foram previamente misturados e homogeneizados e submetidos a um pré-tratamento com KOH 6%. As biomassas previamente pré-tratadas com KOH 6% foram extraídas com água para a obtenção das carragenas e dos resíduos. As frações obtidas no processamento foram caracterizadas quimicamente. Os resíduos foram hidrolisados enzimaticamente com celulases comerciais. Resultados: Foram diferenciados três níveis de produtividade (A, setembro-dezembro de 2013; B, janeiro-março de 2014; C, abril-junho 2014). Os valores de produtividade foram maiores no nível B e intermediários nos níveis A e C. Os val... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The fungus of genus Paracoccidioides is the etiological agent of paracoccidioidomycosis (PCM), an important mycosis in Brazil and Latin America. There are different available therapies, as antifungals belong to the class of polyenes, azoles and sulfonamides. The development of new antifungal agents with greater effectiveness is required to prevent relapse and reduce side effects, the period of treatment and sequelae. The gallic acid molecule with different modifications (alkyl gallates) showed antifungal activity against a representative panel of pathogenic fungi. The decyl gallate (G14) was the study object of this work, for which the Paracoccidioides-host interaction was connected with the mechanism of action. Therefore, the fungus Paracoccidioides lutzii (Pl01) was challenged with the G14 to analyze the changes in the development of budding and cell viability by MTT assay. Then, it was assessed the influence of the G14 in the interaction rate of Pl01 with murine alveolar macrophage lineage AMJ2-C11, with mammalian lung lineage A549 and MRC-5, and hemocytes of Galleria mellonella larvae using assays by flow cytometry. The compound G14 was evaluated for survival rate of infected G. mellonella larvae and to capacity of modulation of nitric oxide production in RAW macrophages. The mechanism of action was performed by chemical-genetic interaction assay followed by genetic interaction, which involves comparing a mutant collection, of Saccharomyces cerevisiae yeast, with hypersensitive profile to G14 to double mutant database to predict via affected. In P. lutzii (Pl01)... (Complete abstract click electronic access below)
Mestre
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Bottet, Fabienne. "La prise en charge du risque thérapeutique." Bordeaux 2, 1997. http://www.theses.fr/1997BOR2M107.
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TISSEYRE, BOINET NATHALIE. "La responsabilite du fait des produits defectueux imputable aux producteurs de medicaments." Paris 11, 1998. http://www.theses.fr/1998PA111006.
Full textAbstract:
Dans les dernieres decennies, la securite du consommateur a tendu a devenir un veritable droit que la societe a le devoir de defendre, face a une industrie innovatrice et puissante. Et lorsque le consommateur est un malade, ce droit est apparu plus imperieux encore, en relation avec une industrie du medicament dont la recherche conduit a des molecules toujours plus performantes, et, partant, potentiellement plus dangereuses. La, le droit a la securite a revetu une dimension politique, prefigurant peut-etre de facon exemplaire une aspiration generale a une indemnisation quasiment absolue des dommages. En france, ou la jurisprudence, puis la loi, ont constamment ameliore la protection de la victime d'un produit defectueux, la notion a fini par etre acceptee d'une obligation generale de securite dont nous avons dessine l'etendue. Mais la directive europeenne du 25 juillet 1985 marquait une etape de plus en instaurant une responsabilite aggravee des producteurs. En un moment ou, avec 10 annees de retard, la france va devoir transposer ses dispositions dans le droit interne, notre propos a ete, en nous attachant au secteur du medicament, d'etudier, d'une part, l'impact de la directive sur le droit francais et, d'autre part, les conditions d'instauration d'un regime de responsabilite objective. Fruit d'une logique de compromis, la directive ouvre des options, notamment quant a l'indemnisation du risque de developpement dont nous avons envisage les inconvenients. Nous nous sommes attachee a montrer que les dispositions de la directive apparaissent moins novatrices par rapport au droit francais que d'aucuns ont voulu le dire. Par ailleurs, nous croyons qu'elles repondent mal aux objectifs fixes : l'harmonisation desiree laissera subsister des regimes de severite inegale, et peut conduire a une indemnisation contestable. Reconnaissant cependant la necessite de mettre en oeuvre une responsabilite objective, specialement en ce qui concerne le produit-medicament, nous avons montre l'interet d'un systeme de garantie collective, si possible elargi de facon a couvrir l'alea therapeutique en son ensembleIn the past decades, consumers's safety has become a right that society has the obligation to defend from a powerful and inovative industry. This right has seemed even more important when the consumer is a sick person because research in the pharmaceutical industry develops molecules that are always more efficient and, therefore, potentially more and more dangerous. This is why the right to safety has become political, illustrating in a very exceptional way a general tendency to fall indemnification of damages suffered. To france, where case law and law have constantly improved the protection of victims of defective products, the idea of a general safety obligation, the scope of which we have determined, has finally been accepted. A step further was taken with the european directive of july 25, 1985 which increases the manufacturer's liability. At a time where france must transpose this directive into its legal system, although it should have been done ten years ago, our purpose has been to study, on the one hand, the impact of this directive on french law with respect to the medicine field and, on the second hand, the terms and conditions of setting up a system of objective liability. Because it results from a compromise, the directive provides alternatives, specially regarding the indemnification of the risk of -- the drawbacks of which we had foreseen. We have tried to prove that the provisions of the directive were less inovating with respect to french law than it was said at first. Besides, we believe that the directive does not achieve its goals set : the harmonisation will maintain various systems with various degrees of severeness which may lead to disputable indemnification. However, acknowledging the necessity to set up a system of objective liability, specially with respect to medicine, we have confirmed the interest of a collective garantee which will hopefully be extended to cover medical hazard in general
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Kalėdaitė, Jurgita. "AB „ALITA“ PRODUKTŲ VARTOTOJŲ LOJALUMO KŪRIMAS." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20060524_111042-88339.
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SUMMARY
Jurgita Kalėdaitė
Creation of loyalty of users of the production of the stock company „Alita“
Graduation dissertation of the graduate studies, 78 pages, 23 pictures, 5 tables, 52 sources of literature, 6 appendixes, Lithuanian.
Key words: loyalty, loyalty of users, creation of loyalty.
Object of the research – loyalty of users for the SC „Alita“.
Matter of the research – creation of loyalty of users.
Purposes of the work:
1) to identify the factors, which form loyalty of users, to classify them into groups according to the level of their loyalty;
2) to give recommendations for stimulation of loyalty of users on a basis of the results of the empiric research.
Tasks:
1) to analyze scientific literature according to the aspect of loyalty of users;
2) to analyze the current situation, to pick out the measures for stimulation of loyalty used by the company;
3) to question customers of the company, to estimate their loyalty for the production of the company;
4) to identify the factors, which stimulate loyalty of users;
5) to give recommendation for stimulation of loyalty of users.
Methods of the research – these methods of the research were used to research this problem and to receive theoretic and practical results: a systematic analysis, a comparative analysis and a cross analysis, graphical of loyalty of users groups.
To estimate effective measures, which help to stimulate loyalty of current users and to form loyalty of potential customers of the stock company... [to full text]
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Lenherr, Thomas. "Taxonomy and applications of alias analysis." Zürich : ETH, Department of Computer Science, [Institut für Computersysteme], 2008. http://e-collection.ethbib.ethz.ch/show?type=dipl&nr=415.
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Gorreto, López Lucía. "Proyecto ALITA (Asma LIbre de TAbaco)." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/400014.
Full textAbstract:
Justificación: El hábito tabáquico es la primera causa de morbilidad y
mortalidad prevenible a nivel mundial. Existen estudios que indican que los
asmáticos con este hábito están peor controlados. Es relevante realizar un
estudio para evaluar una intervención en tabaquismo en estos pacientes, y
analizar el efecto sobre el control del asma, el efecto sobre la cesación
tabáquica y sobre el mayor o menor uso de corticoides inhalados.
Hipótesis: Una Intervención avanzada para la cesación tabáquica mejora el
control del asma.
Objetivo: El objetivo principal del estudio era evaluar la efectividad de una
intervención para la cesación tabáquica en la mejora del control del asma. Los
objetivos secundarios Evaluar la efectividad de la intervención recogida por la
tasa de cesación a los 3, 6 y 12 meses y evaluar el efecto de la intervención en
la disminución del uso de corticoides inhalados.
Material y métodos: Ensayo clínico aleatorizado abierto. Los pacientes se
aleatorizan en 2 ramas, el grupo control sigue el tratamiento habitual y al grupo
intervención se le ofrece una intervención avanzada grupal de deshabituación
tabáquica. Se selecciona una muestra aleatoria de 158 pacientes asmáticos
persistentes y fumadores activos pertenecientes a diferentes centros de
atención primaria de la isla de Mallorca. Ambos grupos realizaron 4 visitas de
seguimiento durante el año que duró el ensayo clínico con el mismo contenido
en las mismas. El grupo intervención acudió un taller de deshabituación
tabáquica que constaba de 6 sesiones de terapia cognitivo conductual
específica para su patología y prescripción de fármacos para la deshabituación
tabáquica que tomaban si consideraban oportuno y a posteriori pasaban a
recibir el mismo seguimiento que el grupo control.
Resultados: La intervención avanzada grupal se muestra efectiva en la mejora
del control del asma aunque no más que otras intervenciones. El factor género
es un factor determinante en la deshabituación de los pacientes asmáticos El
porcentaje de cesación del grupo intervención al final del ensayo fue del 22.2%,
a pesar de que no utilizaron fármacos para la deshabituación más que en un
0.05% del total del grupo.
La disminución de los corticoides inhalados se produjo más en el grupo
intervención, un 52,8%, aunque no de forma significativa, el resto de
participantes permanecieron con la misma pauta de corticoide inhalados, es
decir, no modificaron sus pautas.
Aplicabilidad de los resultados esperados: La intervención demuestra ser
efectiva, por lo que se podría recomendar e implementar de forma activa
desde atención primaria y su aplicación a todos los asmáticos fumadores, así
como a otros pacientes con patologías crónicas respiratorias.Justification: Smoking is the first cause of preventable morbidity and mortality worldwide. Studies indicate asthmatics current smokers are poor controlled. It’s important to elaborate studies to evaluate smoking intervention in this kind of patients, and analyse the effect on asthma control, the effect on smoking cessation and the greater or lesser use of inhaled corticosteroids. Hypothesis: A group-advanced intervention for smoking cessation improves asthma control assessed by Asthma Control Test (ACT). Aims: The main objective of the study was evaluating the effectiveness of a group intervention for smoking cessation in improving asthma control. Secondary objectives were to evaluate the effectiveness of the group intervention collected by cessation rates at finish the intervention, 3, 6 and 12 month, and to evaluate the effect of the intervention on the use of inhaled corticosteroids. Material and methods: Open randomized clinical trial. Patients were randomized into two branches, control group with the usual treatment and follows, and intervention group that was offered group advanced intervention for smoking cessation. A random simple sample of 158 persistent asthmatics and current smokers from different primary care centres on the Mallorca Island was selected. Both groups underwent four follow-up visits during the year-long trial with the same content in them. The intervention group a workshop smoking cessation consisting of six sessions of specific cognitive behavioural therapy for their condition and prescription drugs for smoking cessation treatment taking if considered appropriate and subsequently passed to receive the same monitoring control group. Results: Group advanced intervention shown effectiveness in improving asthma control but not more than the other interventions. The gender factor is determining factor in the cessation of asthmatic patients. The cessation rate of the intervention group at the end of the assay was 22.2%. Despite the recommendations the patients of the intervention group don’t use drugs for smoking cessation, only 0.05% of the total of the group use. Decreased use of inhaled corticosteroids occurred more in the intervention group, 52.8%, but not significantly, the other participants stayed with the same dose of inhaled corticosteroids, no change their treatments. Applicability of the results: The group intervention for smoking cessation shown effectiveness, like other smoking cessation intervention, in improving asthma control, so it could be recommended and it could be implemented actively from primary care and its application to all asthmatics smokers, as well as others patients with chronic respiratory diseases.
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Belli, Guido <1986>. "Liberismo economico ed alea nel contratto." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amsdottorato.unibo.it/6808/.
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La tesi analizza il rapporto tra rischio e liberalismo economico nel contratto e la qualificazione giuridica dei contratti in prodotti finanziari derivati.The thesis analyzes the relationship between risk and economic liberalism in the contract and the legal classification of financial derivatives.
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Alda, Willi [Verfasser]. "Zum Schwingkriechen von Beton / Willi Alda." Braunschweig : Institut für Baustoffe, Massivbau und Brandschutz IBMB, 2014. http://d-nb.info/1231993553/34.
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