Dissertations / Theses on the topic 'Alcohol'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Alcohol.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Beachel, Debi K. "Alcohol beliefs versus alcohol behaviors." Menomonie, WI : University of Wisconsin--Stout, 2005. http://www.uwstout.edu/lib/thesis/2005/2005beacheld.pdf.
Full textGarcía, Bofill Miquel. "Use of alcohol dehydrogenase and alcohol oxidase to convert alcohols in two valuable products: chlorolactone and vanillin." Doctoral thesis, Universitat Autònoma de Barcelona, 2021. http://hdl.handle.net/10803/673116.
Full textLas enzimas presentan una serie de ventajas catalíticas respecto a los catalizadores químicos empleados en síntesis química clásica: especificidad, selectividad y la posibilidad de trabajar en condiciones suaves de temperatura y presión. No obstante, también presentan una serie de limitaciones como son la baja estabilidad y las bajas productividades. En el presente trabajo se combinan dos técnicas para tratar de optimizar las reacciones de interés seleccionadas: la inmovilización y la ingeniería de reacción. Las reacciones objetivo de este trabajo son reacciones de oxidoreducción centradas en la biosíntesis de moléculas, de medio y alto valor añadido, de alto interés industrial. En la primera parte de la tesis se ha utilizado una alcohol deshidrogenasa (ADH99) para la oxidación del alcohol chlorolactol a chlorolactona y una NAD(P)H oxidasa (NOX) como sistema de regeneración del cofactor. La chlorolactona es un precursor para la síntesis de estatinas las cuales son fármacos utilizados para la reducción del LDL-colesterol puesto que inhiben la enzima encargada de su biosíntesis. Ambas enzimas fueron inmovilizados eficientemente en diferentes soportes, de los cuales se seleccionaron los tres que mostraron mayor actividad retenida. Seguidamente se estudió la estabilidad de los derivados inmovilizados en condiciones de reacción y se determinó la carga enzimática máximo para cada enzima. Se descartó el uso de la NOX inmovilizada puesto que no se mejoró la estabilidad con ningún apoyo. Posteriormente se optimizaron las condiciones de reacción con un diseño experimental (DoE) con la ADH99 soluble pero utilizando la cantidad máxima de ADH99 que se puede añadir a la reacción cuando se usa la ADH99 inmovilizada en epoxy-agarosa-UAB M2. Finalmente se estudió la capacidad de reutilización del derivado inmovilizado, donde se pudo mejorar 1.5 veces tanto el producto obtenido como el rendimiento del biocatalizador. No obstante, la mejor configuración resultó ser la utilización de las dos enzimas en forma soluble. La segunda parte de esta tesis se centró en la reacción de oxidación del alcohol vanillínico a vanillina biocatalizada por la eugenol oxidasa (EUGO). La vanillina es la molécula que da las propiedades organolépticas a la vainilla, el segundo aromatizante más caro del mundo. La síntesis de vainillina vía biotecnológica es de un gran interés industrial puesto que puede etiquetarse como natural. La EUGO fue inmovilizada eficientemente en diferentes soportes de los que se seleccionaron los tres que retuvieron más actividad y se estudiaron los mismos parámetros que en el apartado anterior. En este caso los tres derivados inmovilizados fueron utilizados para realizar la reacción de síntesis, con el objetivo de seleccionar el más estable operacionalmente. Todos los derivados permitieron ser reutilizados 5 veces conservando una elevada conversión en el último ciclo. La epoxy-agarosa-UAB M2 fue el soporte que mejor estabilidad mostró. Los buenos resultados obtenidos en el segundo apartado de este trabajo permitieron profundizar en esta reacción. Por lo que, en el tercer apartado, se realizó una optimización de las condiciones de reacción desde el punto de vista de mejorar las métricas del proceso y también con el objetivo de hacer el proceso más sostenible ambientalmente. A la hora de escoger las nuevas condiciones de reacción se tuvieron en cuenta la actividad de la EUGO y su estabilidad. Ambas condiciones fueron testadas en la reacción diana con lo EUGO soluble e inmovilizada. En las nuevas condiciones se pudo mejorar la productividad volumétrica 5.7 y 6.6 veces respectivamente, en comparación a las condiciones previas. Finalmente, en el reciclaje de la enzima inmovilizada se pudieron realizar 5 ciclos de reacción en las primeras condiciones y 18 ciclos de reacción en las nuevas condiciones donde se pudo mejorar el rendimiento del biocatalitzador 3.9 y 12.4 veces respectivamente.
Enzymes have some catalytic advantages over chemical catalysts used in classical chemical synthesis: specificity, selectivity and the possibility to work under mild conditions of temperature and pressure. However, they also have some limitations such as low stability and low productivity. This work combines two techniques aiming to optimise the target reactions: immobilisation and reaction engineering. The target reactions of this work are redox reactions focused on the biosynthesis of molecules, of medium-high value, of industrial interest. In the first part of the thesis, an alcohol dehydrogenase (ADH99) was used, with an NAD(P)H oxidase (NOX) as a cofactor regeneration system, to oxidise a chlorolactol to chlorolactone. Chlorolactone is a precursor for the synthesis of statins which are drugs used to lower LDL-cholesterol by inhibiting the enzyme responsible for its biosynthesis. Both enzymes were efficiently immobilised on different supports, selecting the three that showed the highest retained activity. The stability of the immobilised derivatives under reaction conditions was studied and the maximum enzyme load for each enzyme also was determined. The use of immobilised NOX was discarded because no stability improvements were achieved with any support. The reaction conditions were optimised by design of experiments (DoE), using soluble ADH99 added at maximum loading onto an epoxy-agarose support. Finally, the reusability of the immobilised enzyme was studied, where both the total product obtained and the biocatalyst yield could be improved 1.5-fold. However, the best configuration resulted from the use of the two enzymes in soluble form. The second part of this thesis was focused on the oxidation reaction of vanillyl alcohol to vanillin catalysed by eugenol oxidase (EUGO). Vanillin is the molecule that gives vanilla its organoleptic properties. Vanillin biotechnological synthesis is of high interest industrially because it is the second most expensive flavouring in the world and the product can be labelled as natural. Similar to the previous section, EUGO was efficiently immobilised onto different supports, selecting the three that retained most activity. These supports were used to study the stability of the immobilised enzyme and the maximum EUGO load that can be immobilised. In this case, the three immobilised derivatives were used to perform the target reaction, in order to select the most stable operationally. All immobilised derivatives could be reused 5 times maintaining a high conversion in the last cycle. Epoxy-agarose-UAB M2 was the support that showed the best stability, improving the biocatalyst yield 3-fold. The encouraging results obtained in the second section of this work allowed us to deepen the study of this reaction. Therefore, in the third section, an optimisation of the reaction conditions was carried out to improve the process metrics and also aiming to make the process more environmentally sustainable. The EUGO activity and its stability were taken into account to choose the reaction conditions. Both conditions, maximum activity and maximum stability, were tested in the target reaction with soluble and immobilised EUGO. Using the new conditions, it was possible to improve the volumetric productivity 5.7 and 6.6-fold respectively, compared to the previous conditions. Finally, the reusability of the immobilised EUGO allowed us to perform 5 reaction cycles and 18 reaction cycles, with unoptimised and optimised reaction conditions respectively. This resulted in an improvement of the biocatalyst yield of 3.9 and 12.4-fold, respectively, compared to reactions with soluble enzyme under the same conditions.
Universitat Autònoma de Barcelona. Programa de Doctorat en Biotecnologia
Sumer, Burak. "Synthesis Of 1,2-amino Alcohols Having Tertiary Alcohol Moiety." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607276/index.pdf.
Full textBarroca, Pedro JoseÌ Pereira Marques. "Alcohol oxidase enzymes for the deracemization of secondary alcohols." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427019.
Full textCornmell, Robert Joseph. "Enantioselective alcohol oxidase enzymes for deracemisation of secondary alcohols." Thesis, University of Liverpool, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406826.
Full textThom, Elizabeth Whyte. "Alcohol treatment policy 1950-1990 : from alcohol treatment to alcohol problems management." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1997. http://researchonline.lshtm.ac.uk/682245/.
Full textPulido, Carmen. "Alcohol cue reactivity task development /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC IP addresses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3312073.
Full textGreco, Michelle Nicholle. "The relation of alcohol expectancies to alcohol consumption and alcohol-related problems among college students." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.
Full textLong, Elizabeth C. "Developmental Trajectories of Alcohol Use and Alcohol Use Disorder." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/5111.
Full textBarbosa, Carolina Pinto Pereira. "Economic evaluation of alcohol treatments : linking drinking patterns, alcohol consequences and cost effectiveness of alcohol treatments." Thesis, University of York, 2010. http://etheses.whiterose.ac.uk/815/.
Full textLevine, Misha Boris. "The 1985 alcohol reform in the USSR : a case of rejected moral reform /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0033/NQ66219.pdf.
Full textBrightbill, Beverlyn. "Alcohol consumption and college students relating students' alcohol use to family roles, positions and family alcohol use /." Instructions for remote access. Click here to access this electronic resource. Access available to Kutztown University faculty, staff, and students only, 1988. http://www.kutztown.edu/library/services/remote_access.asp.
Full textMcQuire, Cheryl. "Epidemiology of prenatal alcohol use and fetal alcohol spectrum disorder." Thesis, Cardiff University, 2018. http://orca.cf.ac.uk/110919/.
Full textJaishankar, Gayatri. "Fetal Alcohol Syndrome." Digital Commons @ East Tennessee State University, 1995. https://dc.etsu.edu/etsu-works/8867.
Full textChand, A. "Water-alcohol miscibilities." Thesis, Chand, A. (1990) Water-alcohol miscibilities. PhD thesis, Murdoch University, 1990. https://researchrepository.murdoch.edu.au/id/eprint/51594/.
Full textStigall, Logan Alexander. "Examining alcohol alcohol abuse, perceptions of alcohol abuse, and emotional/verbal aggression in romantic relationships using multiple measures." Kent State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=kent1510670996108155.
Full textCruz, Iris. "DECREASING ALCOHOL USE AMONG HIGH SCHOOL STUDENTS BY CHALLENGING ALCOHOL EXPECTANCIES." Doctoral diss., University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2798.
Full textPh.D.
Department of Psychology
Sciences
Psychology
Okore, Jeremiah K. "The Impact of Alcohol Beverage Price and Tax on Alcohol Consumption." Youngstown State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1433437600.
Full textBrabenec, Tomáš. "Did the alcohol prohibition reduce motor vehicle accidents related to alcohol?" Master's thesis, Vysoká škola ekonomická v Praze, 2015. http://www.nusl.cz/ntk/nusl-264121.
Full textMakofane, D. S. "Family members' experiences of living with people who consume home-brewed alcohol (spayoni) in Oakley Village, Enhlanzeni District, Mpumalanga Province : a social work perspective." Thesis, University of Limpopo, 2019. http://hdl.handle.net/10386/3061.
Full textThe study was aimed at exploring the family member‟s experiences of living with people who consume home brewed alcohol (spayoni) in Oakley. Oakley is a village based in Ehlanzeni district, Mpumalanga province. The researcher looked into the financial management, balancing of the work-family nexus and the manner in which people that consume spayoni deal with and conduct themselves in violent situations. A qualitative research approach was used by the researcher through an exploratory design. A total number of nine (9) respondents took part in the study. They were identified by the use of a purposive and snowball sampling method. Furthermore, the researcher used a semi-structured interview to collect data which was analysed by a thematic analysis structure. Data obtained from the study reveals that people that consume spayoni spend less time with family members as they are either out at work or drinking spayoni throughout the day. They leave home very early in the morning and come back late at night. Family roles and relationships are negatively affected by their routines. The people that consume spayoni mostly rely in piece jobs hence they don‟t have stable income. Nonetheless, the little money that they get is spent solely on the purchase of spayoni. They do not prioritise financial contribution towards household needs. The study also identified that people that consume spayoni are generally disrespectful when drunk but refrain from violent situations. In order to combat the challenges faced by the family members, internal and external measures should be put in place. The use of community awareness campaigns is one method which can help in reducing the demand of spayoni in Oakley village. Involvement of monitoring bodies such as the Liquor control boards and the local traditional authorities will assist the community to have regulations governing the supply of home brewed alcohol. Family members should also develop platforms of open communication between each other to avoid misunderstandings and build a more positive family environment.
Fang, Che. "Cytokines, alcohol metabolizing enzymes and stress-inducible ER proteins in alcoholic liver disease /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4160-2/.
Full textAriel, Idan. "Social Situations and Alcohol: The Effect of Social Context on Alcohol Expectancies." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/3955.
Full textWilson, Donald L. "College students' alcohol use, parental-familial alcohol use, and family of origin." Virtual Press, 1995. http://liblink.bsu.edu/uhtbin/catkey/941580.
Full textDepartment of Counseling Psychology and Guidance Services
Beckett, Cynthia Diane. "Navajo children and families living with fetal alcohol syndrome/fetal alcohol effects." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/280150.
Full textVonlaufen, Alain Clinical School South Western Sydney Faculty of Medicine UNSW. "Alcohol, endotoxin and the pancreas (induction, progression and reversibility of alcoholic pancreatitis)." Publisher:University of New South Wales. Clinical School - South Western Sydney, 2009. http://handle.unsw.edu.au/1959.4/43721.
Full textCritchlow, Nathan. "An investigation into digital alcohol marketing and user-created alcohol promotion, and the association with young adult's alcohol-related knowledge, attitudes, and behaviour." Thesis, University of Stirling, 2017. http://hdl.handle.net/1893/25798.
Full textLeifman, Håkan. "Perspectives on alcohol prevention." Doctoral thesis, Stockholms universitet, Sociologiska institutionen, 1996. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-82852.
Full textHenderson, Louise M. Rosamond Wayne D. "Alcohol and cardiovascular disease." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,492.
Full textTitle from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Epidemiology, School of Public Health." Discipline: Epidemiology; Department/School: Public Health.
Thomas, Matthew Rhys. "Polyvinyl alcohol surface modification." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:279fe53b-7d61-43de-a91a-be658dd01eda.
Full textJohnson, Stefanie M. "Alcohol quantity and bac." Honors in the Major Thesis, University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1092.
Full textBachelors
Sciences
Psychology
Wright, Linda. "Alcohol and youth work." Thesis, Durham University, 1998. http://etheses.dur.ac.uk/5056/.
Full textBall, David Mark. "Genetics of alcohol dependence." Thesis, King's College London (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410215.
Full textVarvasovsky, Zsuzsa. "Alcohol policy in Hungary." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1998. http://researchonline.lshtm.ac.uk/682262/.
Full textLourenço, Sandra Cristina de Loureiro. "Alcohol consumption and obesity." Master's thesis, Porto : edição de autor, 2009. http://hdl.handle.net/10216/62567.
Full textResumo da tese: Enquadramento: O facto de o álcool ser o segundo componente alimentar com maior densidade energética sustenta a ideia de que consumos elevados ou mesmo moderados, a longo prazo, possam contribuir para o aumento da ingestão energética, e consequentemente conduzir a um aumento do índice de massa corporal dos indivíduos. A variabilidade da ingestão de álcool existente na população Portuguesa permite observar amplitudes de exposição suficientes para melhor estudar esta relação. Objectivo: Quantificação da associação entre a prevalência de obesidade e a ingestão de etanol, numa amostra urbana de adultos portugueses. Métodos: A amostra seleccionada aleatoriamente, era constituída por 2372 indivíduos adultos (mulheres e homens), na avaliação de obesidade total e por 2383 (mulheres e homens), na avaliação de obesidade central. Estes indivíduos faziam parte da coorte do estudo EPIPorto. Inquiridores treinados procederam à aplicação de um questionário estruturado e avaliação de parâmetros sócio-demográficos e antropométricos. Foi definida obesidade total como o Indice de massa corporal (IMC) peso (kg) /altura (m)2) igual ou superior a 30 kg.m2 e central valores de perímetro da cintura (PC) superior a 88 cm ou 102 cm, para mulheres e homens, respectivamente. A ingestão de etanol foi estimada através de um questionário semi-quantitativo de frequência de alimentos, previamente validado, referente ao ano anterior à entrevista, e ao longo da vida. Os indivíduos foram classificados em 4 classes de ingestão de etanol (g/dia): 0; 0, 1-15,0; 15,0; 30,0 nas mulheres e 0; 0,1-30,0; 30,1-60,0; 60,0 nos homens.
Thesis abstract: Background: The high alcohol consumption in Portugal, and the high energy content of alcoholic beverages, makes alcohol a potential contributor to the obesity. Objective: To evaluate the association between ethanol consumption and overall and central obesity in adults of an urban Portuguese population. Methods: This cross-sectional analysis included 2372 for evaluate overall obesity and 2383 for central obesity. The participants were randomly selected from Porto in-habitants (age: 18 years) enrolled in EPIPorto Study (1999-2003). Trained interviewers applied a questionnaire comprising information on social, demographic, behavioural characteristics, and anthropometrical measures were recorded. Data on ethanol intake were obtained by using a validated semi- quantitative food frequency questionnaire. Subjects were classified in to 4 classes of ethanol intake (g/day):0; 0.1-15.0; 15.1-30.0 ;: 30.0 in women and 0; 0.1-30.0; 30.1-60.0 ;: 60.0 in men. Overall obesity was considered when the body mass index (BMI) was: 30.0 kg/m2 , central obesity, if Waist Circumference (WC) was higher than 88 cm or 102 cm, for women and men respectively. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using unconditional logistic regression with separate models fitted for sex. Results: Prevalence of ethanol intake higher than 30g/day for women and 60g/day for men, was 5.3% in obese women vs. 3.3% in non obese, and 28.4% in obese men vs. 15.8% in non obese. After adjustment for age, education, BMI, smoking, energy intake and sports practice, men who consumed more than 60g/day were more frequently obese (overall) comparing with non drinkers (OR=1.64, 95% CI: 1.33-5.22).
Munoz, Miguel. "Alcohol intoxication and emotion." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/20041.
Full textJones, Andrew. "Disinhibition and alcohol consumption." Thesis, University of Liverpool, 2012. http://livrepository.liverpool.ac.uk/9153/.
Full textBruman, Henry J. "Alcohol in Ancient Mexico /." Salt Lake City : University of Utah Press, 2000. http://catalogue.bnf.fr/ark:/12148/cb38908829w.
Full textBibliogr. p. 136-144. Bibliogr. des oeuvres de l'auteur p. 147-148. Index.
Kalk, Nicola Jayne. "Neuroinflammmation in alcohol dependence." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/33232.
Full textLourenço, Sandra Cristina de Loureiro. "Alcohol consumption and obesity." Dissertação, Porto : edição de autor, 2009. http://catalogo.up.pt/F?func=find-b&find_code=SYS&request=000133186.
Full textResumo da tese: Enquadramento: O facto de o álcool ser o segundo componente alimentar com maior densidade energética sustenta a ideia de que consumos elevados ou mesmo moderados, a longo prazo, possam contribuir para o aumento da ingestão energética, e consequentemente conduzir a um aumento do índice de massa corporal dos indivíduos. A variabilidade da ingestão de álcool existente na população Portuguesa permite observar amplitudes de exposição suficientes para melhor estudar esta relação. Objectivo: Quantificação da associação entre a prevalência de obesidade e a ingestão de etanol, numa amostra urbana de adultos portugueses. Métodos: A amostra seleccionada aleatoriamente, era constituída por 2372 indivíduos adultos (mulheres e homens), na avaliação de obesidade total e por 2383 (mulheres e homens), na avaliação de obesidade central. Estes indivíduos faziam parte da coorte do estudo EPIPorto. Inquiridores treinados procederam à aplicação de um questionário estruturado e avaliação de parâmetros sócio-demográficos e antropométricos. Foi definida obesidade total como o Indice de massa corporal (IMC) peso (kg) /altura (m)2) igual ou superior a 30 kg.m2 e central valores de perímetro da cintura (PC) superior a 88 cm ou 102 cm, para mulheres e homens, respectivamente. A ingestão de etanol foi estimada através de um questionário semi-quantitativo de frequência de alimentos, previamente validado, referente ao ano anterior à entrevista, e ao longo da vida. Os indivíduos foram classificados em 4 classes de ingestão de etanol (g/dia): 0; 0, 1-15,0; 15,0; 30,0 nas mulheres e 0; 0,1-30,0; 30,1-60,0; 60,0 nos homens.
Thesis abstract: Background: The high alcohol consumption in Portugal, and the high energy content of alcoholic beverages, makes alcohol a potential contributor to the obesity. Objective: To evaluate the association between ethanol consumption and overall and central obesity in adults of an urban Portuguese population. Methods: This cross-sectional analysis included 2372 for evaluate overall obesity and 2383 for central obesity. The participants were randomly selected from Porto in-habitants (age: 18 years) enrolled in EPIPorto Study (1999-2003). Trained interviewers applied a questionnaire comprising information on social, demographic, behavioural characteristics, and anthropometrical measures were recorded. Data on ethanol intake were obtained by using a validated semi- quantitative food frequency questionnaire. Subjects were classified in to 4 classes of ethanol intake (g/day):0; 0.1-15.0; 15.1-30.0 ;: 30.0 in women and 0; 0.1-30.0; 30.1-60.0 ;: 60.0 in men. Overall obesity was considered when the body mass index (BMI) was: 30.0 kg/m2 , central obesity, if Waist Circumference (WC) was higher than 88 cm or 102 cm, for women and men respectively. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using unconditional logistic regression with separate models fitted for sex. Results: Prevalence of ethanol intake higher than 30g/day for women and 60g/day for men, was 5.3% in obese women vs. 3.3% in non obese, and 28.4% in obese men vs. 15.8% in non obese. After adjustment for age, education, BMI, smoking, energy intake and sports practice, men who consumed more than 60g/day were more frequently obese (overall) comparing with non drinkers (OR=1.64, 95% CI: 1.33-5.22).
Lant, Ginger M. "Social Learning and Alcohol." W&M ScholarWorks, 1999. https://scholarworks.wm.edu/etd/1539626233.
Full textGarbusow, Maria. "Learning in alcohol dependence." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/18810.
Full textThis thesis summarizes the first Pavlovian-to-instrumental transfer (PIT) studies in alcohol-dependent (AD) patients. Contextual stimuli are known to influence our behavior. Animal and human studies showed that positive Pavlovian stimuli enhance and negative Pavlovian stimuli reduce instrumental behavior (PIT effect). This mechanism might be relevant for relapse risk, as drug-associated stimuli have shown to enhance e.g. craving and functional activation in reward-related brain areas in patients compared to controls. In animal and human studies enhanced PIT effects were associated with activation particularly in the nucleus accumbens (NAcc). Moreover, control subjects with stronger PIT effects and AD patients were more impulsive on different facets of impulsivity. The PIT task consists of three main parts: i) instrumental conditioning, ii) Pavlovian conditioning, iii) transfer with Pavlovian background stimuli and instrumental task in the foreground (nondrug-related PIT: Pavlovian contextual cues; drug-related PIT: alcohol-related contextual cues). Choice impulsivity was measured by delay discounting task. We observed significantly enhanced nondrug-related PIT effects in AD patients compared to controls with a functional activation in the NAcc being predictive for relapse. Regarding drug-related PIT effects, we observed significantly reduced instrumental behavior during alcohol-related backgrounds with neural correlates in the NAcc in abstainers only. Choice impulsivity was positively related to PIT in AD patients only. Our data suggest that PIT is a mechanism contributing to relapse in AD patients with functional correlations within the NAcc, which based on our data is involved in motivation and attribution of salience. The subgroup of high impulsive patients is particularly susceptible for PIT effects, thus should be main target for intervention programs.
Richardson, Alison E. "Exploring the relation between cigarette smoking and alcohol hangover frequency." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/4892.
Full textThe entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on November 5, 2007) Includes bibliographical references.
Kersbergen, Inge. "Individual differences in attentional processing of responsible drinking statements in alcohol packaging, public health campaigns and alcohol advertising among alcohol consumers." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3007621/.
Full textLau, Katharina [Verfasser]. "Alcohol consumption, motivation to change drinking behaviour, motivation to seek help for alcohol problem drinking and alcohol-attributable morbidity / Katharina Lau." Greifswald : Universitätsbibliothek Greifswald, 2011. http://d-nb.info/1017586578/34.
Full textKasprzak, Jakub [Verfasser]. "Alcohol dehydrogenases as biocatalysts for the production of enantiomerically pure chiral alcohols / Jakub Kasprzak." Greifswald : Universitätsbibliothek Greifswald, 2017. http://d-nb.info/1123167893/34.
Full textDuke, Aaron. "Agression et comportement coercitif : expérimentations sur l’influence de certains facteurs physiologiques." Thesis, Université Grenoble Alpes (ComUE), 2015. http://www.theses.fr/2015GREAH033.
Full textKey to alleviating the terrible costs of human violence and aggression are identifying and understanding key pharmacological moderators of human aggression. Two primary pharmacological candidates known to influence aggression are alcohol, the intoxicating ingredient of many popular beverages, and serotonin, a class of neurotransmitters important in behavioral regulation. I present four complementary investigations into these two pharmacological targets, examining respectively: (1) the interaction between aggressive personality features and alcohol intoxication, (2) alcohol’s influence on moral reasoning in the face of moral dilemmas involving the use of aggression, (3) the size and strength of the relationship between central serotonin activity and various measures of human aggression, and finally, (4) the ability of Omega-3 supplementation to attenuate aggression via its impact on serotonergic functioning
Benkdane, Merieme. "Rôle protecteur des cellules de Küpffer de phénotype M2 anti-inflammatoire dans la maladie alcoolique du foie." Thesis, Paris Est, 2012. http://www.theses.fr/2012PEST0062.
Full textSummary not transmitted
Neal, Dan J. Carey Kate B. "The relationship between alcohol consumption and alcohol-related problems an event-level analysis /." Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available full text, 2004. http://wwwlib.umi.com/cr/syr/main.
Full textGustafsson, Nina-Katri. "Bridging the world alcohol policy in transition and diverging alcohol patterns in Sweden /." Doctoral thesis, Stockholm : Acta Universitatis Stockholmiensis, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-38858.
Full textAt the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 2: In press. Paper 2: Submitted. Paper 3: Submitted. Härtill 4 uppsatser.
Gorey, Claire M. "Age of Alcohol Initiation and Reward Processes in a Current Alcohol Drinking Sample." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6847.
Full text