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1

Coburn, Ronald F. Airway Smooth Muscle in Health and Disease. Boston, MA: Springer US, 1989.

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2

Chung, Kian Fan, ed. Airway Smooth Muscle in Asthma and COPD. Chichester, UK: John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/9780470754221.

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3

Coburn, Ronald F., ed. Airway Smooth Muscle in Health and Disease. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0779-2.

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4

Wang, Yong-Xiao, ed. Calcium Signaling In Airway Smooth Muscle Cells. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-01312-1.

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5

Workshop on Airway Smooth Muscle (1983 Bethesda, Md.). Report of Workshop on Airway Smooth Muscle, September 25-27, 1983. [Bethesda, Md.?]: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 1985.

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6

National Institutes of Health (U.S.), ed. Report of Workshop on Airway Smooth Muscle, September 25-27, 1983. [Bethesda, Md.?]: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 1985.

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7

Cook, Stephen John. Studies of agonists at b-adrenoreceptors acting on airway smooth muscle. Manchester: University of Manchester, 1993.

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8

Raeburn, David, and Mark A. Giembycz, eds. Airways Smooth Muscle. Basel: Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7558-5.

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9

Raeburn, David, and Mark A. Giembycz, eds. Airways Smooth Muscle: Development, and Regulation of Contractility. Basel: Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7408-3.

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10

Raeburn, David, and Mark A. Giembycz, eds. Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo. Basel: Birkhäuser Basel, 1996. http://dx.doi.org/10.1007/978-3-0348-9000-7.

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11

Raeburn, David, and Mark A. Giembycz, eds. Airways Smooth Muscle: Biochemical Control of Contraction and Relaxation. Basel: Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7681-0.

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12

Raeburn, David, and Mark A. Giembycz, eds. Airways Smooth Muscle: Neurotransmitters, Amines, Lipid Mediators and Signal Transduction. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7504-2.

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13

Raeburn, David, and Mark A. Giembycz, eds. Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7362-8.

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14

Isaac, Lynne Mari. Studies of potassium channel inhibitors and openers acting on airways smooth muscle. Manchester: University of Manchester, 1995.

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15

Wang, Yong-Xiao. Calcium Signaling In Airway Smooth Muscle Cells. Springer, 2016.

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16

Wang, Yong-Xiao. Calcium Signaling In Airway Smooth Muscle Cells. Springer, 2013.

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17

Wang, Yong-Xiao. Calcium Signaling in Airway Smooth Muscle Cells. Springer London, Limited, 2013.

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18

1931-, Coburn Ronald F., ed. Airway smooth muscle in health and disease. New York: Plenum Press, 1989.

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19

K, Agrawal Devendra, and Townley Robert G, eds. Airway smooth muscle: Modulation of receptors and response. Boca Raton: CRC Press, 1990.

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20

K, Agrawal Devendra, and Townley Robert G, eds. Airway smooth muscle: Modulation of receptors and response. Boca Raton: CRC Press, 1990.

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21

Agrawal, Devendra K., and Robert G. Townley. Airway Smooth Muscle: Modulation of Receptors and Response. CRC, 1990.

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22

Coburn, R. F. Airway Smooth Muscle in Health and Disease. Springer, 2011.

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23

Chung, Prof Kian, and Kian Fan Chung. Airway Smooth Muscle in Asthma and Copd. Wiley & Sons, Incorporated, John, 2008.

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24

Raeburn, David, and M. A. Giembycz. Airways Smooth Muscle: Structure, Innervation and Neurotransmission. Birkhauser Boston, 1994.

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25

1953-, Raeburn D., and Giembycz M. A. 1961-, eds. Airways smooth muscle: Structure, innervation, and neurotransmission. Basel: Birkhäuser Verlag, 1994.

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26

1953-, Raeburn D., and Giembycz M. A. 1961-, eds. Airways smooth muscle: Development, and regulation of contractility. Basel: Birkhäuser Verlag, 1994.

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27

1953-, Raeburn D., and Giembycz M. A. 1961-, eds. Airways smooth muscle: Biochemical control of contraction and relaxation. Basel: Birkhäuser Verlag, 1994.

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28

(Editor), David Raeburn, and M. A. Giembycz (Editor), eds. Airways Smooth Muscle: Development, and Regulation of Contractility (Respiratory Pharmacology and Pharmacotherapy). Birkhauser Boston, 1994.

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29

Raeburn, D. Airways Smooth Muscle: Structure, Innervation, and Neurotransmission (Progress in Mathematics). Birkhauser, 1994.

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30

Chung, Kian Fan. Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology. Wiley & Sons, Incorporated, John, 2008.

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31

Chung, Kian Fan. Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology. Wiley & Sons, Limited, John, 2008.

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32

Airway Smooth Muscle In Asthma And Copd Biology And Pharmacology. John Wiley & Sons, 2008.

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33

Raeburn, D. Airways Smooth Muscle: Peptide Receptors, Ion Channels, and Signal Transduction (Agents and Actions Supplements). Birkhauser, 1995.

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34

1953-, Raeburn D., and Giembycz M. A. 1961-, eds. Airways smooth muscle: Modelling the asthmatic response in vivo. Basel: Birkhäuser Verlag, 1996.

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35

(Editor), David Raeburn, and M. A. Giembycz (Editor), eds. Airways Smooth Muscle: Modelling the Asthmatic Response in Vivo (Respiratory Pharmacology and Pharmacotherapy). Birkhauser, 1996.

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36

(Editor), David Raeburn, and Mark A. Giembycz (Editor), eds. Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo (Respiratory Pharmacology and Pharmacotherapy). Birkhauser, 1996.

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37

Tallet, Julio. Presence of an autocrine role for prostaglandin E₂ in isolated canine airway smooth muscle. 1991.

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38

G, Stewart Alastair, ed. Airway wall remodelling in asthma. Boca Raton: CRC Press, 1997.

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39

Wuyts, Wim. Human Airway Smooth Muscle Cells: Role in Chronic Inflammatory Disorders of the Lung (Acta Biomedica Lovaniensia, 304). Leuven Univ Pr, 2003.

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40

Jeffrey, Andrew, Abdul Nasimudeen, and Joshua Agbetile. Asthma. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0133.

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Asthma is a disorder of airway smooth muscle and airway inflammation, manifested by variable airflow limitation. This definition continues to be refined in light of developments in the understanding of asthma’s pathophysiology, immunology, and treatment.
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41

Airway Wall Remodelling in Asthma (Handbooks in Pharmacology and Toxicology). Informa Healthcare, 1996.

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42

1953-, Raeburn D., and Giembycz M. A. 1961-, eds. Airways smooth muscle: Peptide receptors, ion channels, and signal transduction. Basel: Birkhäuser Verlag, 1995.

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43

(Editor), E. Raeburn, and M. A. Giembycz (Editor), eds. Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction (Respiratory Pharmacology and Pharmacotherapy). Birkhauser Boston, 1995.

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44

Pintelon, Isabel, Jean-Pierre Timmermans, Inge Brouns, and Dirk Adriaensen. Novel Insights in the Neurochemistry and Function of Pulmonary Sensory Receptors. Springer, 2011.

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45

Novel Insights In The Neurochemistry And Function Of Pulmonary Sensory Receptors. Springer, 2011.

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46

Manlapaz, Mariel, and Perin Kothari. Neuromuscular Disorders and Anesthesia. Edited by David E. Traul and Irene P. Osborn. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190850036.003.0029.

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The various neuromuscular diseases present with different airway, cardiovascular, pulmonary, and anesthetic considerations. It is useful to categorize these different diseases into nerve, neuromuscular junction, and primary muscle diseases. Understanding their pathophysiology is paramount in choosing the right anesthetic drugs (for example, depolarizing versus nondepolarizing and regional versus general anesthesia). Knowing their manifestations such as autonomic dysfunction, skeletal/cardiac/smooth/bulbar muscle involvement, or tendency for tonic contraction, allows for expectant perioperative management. Finally appreciating their association with certain disease states such as malignant hyperthermia or endocrine dysfunction can prevent complications. A brief review of myotonic dystrophy is presented here, followed by a brief summary of anesthetic considerations for various neuromuscular diseases.
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47

Airways Smooth Muscle: Structure, Innervation and Neurotransmission. Birkhäuser, 2012.

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48

Raeburn, David, and Mark A. Giembycz. Airways Smooth Muscle: Structure, Innervation and Neurotransmission. Birkhäuser, 2012.

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49

Raeburn, David, and Mark A. Giembycz. Airways Smooth Muscle: Structure, Innervation and Neurotransmission. Birkhauser Verlag, 2013.

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50

Lin, Michael, and Erin S. Williams. Open Globe Repair. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0030.

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Penetrating eye injury in the pediatric patient is an emergency that requires careful management by the anesthesiologist to prevent further eye damage by the potential extrusion of vitreous fluid. Additionally, since these injuries are due to trauma, the patients typically are not adequately fasted for surgery. Thus prevention of aspiration of gastric contents must also be considered during the perioperative management of the child with an open globe injury. Depending on the risk of aspiration, the anesthesiologist must determine whether to use succinylcholine, a nondepoloarizing muscle relaxant, or no muscle relaxant at all, prior to laryngoscopy. A delicate balance must exist to achieve a smooth induction of anesthesia, blunted response to airway stimulation during laryngoscopy and intubation, and prevention of aspiration. During the perioperative period, the pediatric anesthesiologist can employ a variety of methods to limit the potential for increased intraocular pressure in the patient with penetrating eye trauma.
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