Relevant bibliographies by topics / AIDS (Disease) – Patients

Academic literature on the topic 'AIDS (Disease) – Patients'

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Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "AIDS (Disease) – Patients"

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Thomsen, Hauke, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, and Kari Hemminki. "Familial associations for Addison’s disease and between Addison’s disease and other autoimmune diseases." Endocrine Connections 9, no. 11 (November 2020): 1114–20. http://dx.doi.org/10.1530/ec-20-0328.

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Design Addison’s disease (AD) is a rare autoimmune disease (AID) of the adrenal cortex, present as an isolated AD or part of autoimmune polyendocrine syndromes (APSs) 1 and 2. Although AD patients present with a number of AID co-morbidities, population-based family studies are scarce, and we aimed to carry out an unbiased study on AD and related AIDs. Methods We collected data on patients diagnosed with AIDs in Swedish hospitals and calculated standardized incidence ratios (SIRs) in families for concordant AD and for other AIDs, the latter as discordant relative risks. Results The number of AD patients was 2852, which accounted for 0.4% of all hospitalized AIDs. A total of 62 persons (3.6%) were diagnosed with familial AD. The SIR for siblings was remarkably high, reaching 909 for singleton siblings diagnosed before age 10 years. It was 32 in those diagnosed past age 29 years and the risk for twins was 323. SIR was 9.44 for offspring of affected parents. AD was associated with 11 other AIDs, including thyroid AIDs and type 1 diabetes and some rarer AIDs such as Guillain–Barre syndrome, myasthenia gravis, polymyalgia rheumatica and Sjögren’s syndrome. Conclusions The familial risk for AD was very high implicating genetic etiology, which for juvenile siblings may be ascribed to APS-1. The adult part of sibling risk was probably contributed by recessive polygenic inheritance. AD was associated with many common AIDs; some of these were known co-morbidities in AD patients while some other appeared to more specific for a familial setting.
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Kohan, Darius, Paul E. Hammerschlag, and Roy A. Holliday. "Otologic Disease in AIDS Patients." Laryngoscope 100, no. 12 (December 1990): 1326???1330. http://dx.doi.org/10.1288/00005537-199012000-00016.

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Weissler, Jonathan C., and Ann R. Mootz. "Pulmonary Disease in AIDS Patients." American Journal of the Medical Sciences 300, no. 5 (November 1990): 330–43. http://dx.doi.org/10.1097/00000441-199011000-00010.

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Chen, Yahong, Jinjin Yuan, Xianlin Han, Xiaolong Liu, Xiao Han, and Hanhui Ye. "Coexpression Analysis of Transcriptome on AIDS and Other Human Disease Pathways by Canonical Correlation Analysis." International Journal of Genomics 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/9163719.

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Acquired immune deficiency syndrome is a severe disease in humans caused by human immunodeficiency virus. Several human genes were characterized as host genetic factors that impact the processes of AIDS disease. Recent studies on AIDS patients revealed a series disease is complicating with AIDS. To resolve gene interaction between AIDS and complicating diseases, a canonical correlation analysis was used to identify the global correlation between AIDS and other disease pathway genes expression. The results showed that HLA-B, HLA-A, MH9, ZNED1, IRF1, TLR8, TSG101, NCOR2, and GML are the key AIDS-restricted genes highly correlated with other disease pathway genes. Furthermore, pathway genes in several diseases such as asthma, autoimmune thyroid disease, and malaria were globally correlated with ARGs. It suggests that these diseases are a high risk in AIDS patients as complicating diseases.
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Wilcox, C. Mel, and Klaus E. Mönkemüller. "Hepatobiliary Diseases in Patients with AIDS: Focus on AIDS Cholangiopathy and Gallbladder Disease." Digestive Diseases 16, no. 4 (1998): 205–13. http://dx.doi.org/10.1159/000016868.

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Hamm, Hinrich, and Heinrich Matthys. "Pleural disease in patients with AIDS." Current Opinion in Pulmonary Medicine 3, no. 4 (July 1997): 315–18. http://dx.doi.org/10.1097/00063198-199707000-00014.

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Bini, Edmund J., and David L. Diehl. "Colonic disease in patients with AIDS." Techniques in Gastrointestinal Endoscopy 4, no. 2 (April 2002): 77–85. http://dx.doi.org/10.1053/tgie.2002.33010.

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Khondker, Lubna. "Dermatological Manifestations of HIV/AIDS Patients." Journal of Enam Medical College 9, no. 3 (September 22, 2019): 185–88. http://dx.doi.org/10.3329/jemc.v9i3.43249.

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Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/ AIDS) is a global pandemic. According to Global HIV & AIDS statistics 2018, approximately 36.9 million people are living with HIV globally, 77.3 million [59.9 million–100 million] people have become infected with HIV since the start of the epidemic, 35.4 million [25.0–49.9 million] people died from AIDS-related illnesses since the start of the epidemic and 940000 [670000–1.3 million] people died from AIDS-related illnesses in 2017. It weakens a person’s immune system by destroying important cells that fight disease and infection. Dermatologic diseases are common in the HIV-infected population. Skin disease can be uniquely associated with HIV disease and many of the cutaneous diseases are not unique to this group, but the presentation can be more severe and recalcitrant to treatment. The spectrum of skin conditions includes skin findings associated with primary HIV infection and a broad range of skin problems related to the immune deficiency of advanced AIDS. Recognition of characteristic eruptions can facilitate early diagnosis of HIV. A broad variety of neoplastic, infectious and non-infectious diseases can manifest in the skin and may alert the clinician of declining of the immune system. This article reviews the current spectrum of HIV-associated skin conditions, focusing on common complaints, infections, drugassociated toxicity and malignancies based on recently published literature relevant to this area. J Enam Med Col 2019; 9(3): 185-188
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Kohan, Darius, Stephen G. Rothstein, and Noel L. Cohen. "Otologic Disease in Patients with Acquired Immunodeficiency Syndrome." Annals of Otology, Rhinology & Laryngology 97, no. 6 (November 1988): 636–40. http://dx.doi.org/10.1177/000348948809700611.

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A 5-year retrospective study evaluating otologic disease in patients with acquired immunodeficiency syndrome (AIDS) was conducted at the New York University Medical Center-Bellevue Hospital Center. Twenty-six patients with documented otologic disease who met the Centers for Disease Control criteria for AIDS were identified and their charts were analyzed according to presenting complaints, physical examination, diagnostic modalities, pathologic condition, management, and outcome. A marked diversity of otologic diseases of varying severity was noted. The majority of patients complained of hearing loss and otalgia during their hospitalization for treatment of AIDS-related opportunistic infections. The most frequent diagnoses were otitis externa, acute otitis media, and otitis media with effusion. Sensorineural hearing loss frequently appeared to be related to ototoxic medications and neurologic infections.
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Soare, Alina, Simona Pintilie, Ana Maria Gherghe, Alexandra Radu, Rucsandra Dobrota, Mariana Sasu, Mihai Bojinca, Victor Stoica, and Carina Mihai. "PATIENTS WITH SYSTEMIC SCLEROSIS ASSOCIATING OTHER AUTOIMMUNE DISEASES HAVE A MILDER DISEASE COURSE." Romanian Journal of Rheumatology 24, no. 2 (June 30, 2015): 114–17. http://dx.doi.org/10.37897/rjr.2015.2.8.

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Background and objectives. Systemic sclerosis (SSc) is a multisystem connective tissue disease (CTD), being one of the most heterogeneous diseases of the spectrum of CTDs. It may associate other autoimmune diseases (AIDs), therefore in this study we aimed to evaluate the prevalence of other AIDs in a cohort of patients with SSc and to evaluate their prognosis in comparison to patients with SSc without this association. Patients and methods. We performed a retrospective study in patients with SSc satisfying the ACR 1980 or the ACR/EULAR 2013 criteria, who were evaluated between January 2005 and May 2014 in our SSc center. These patients were investigated according to the EUSTAR recommendations, including modified Rodnan Skin Score (mRSS), lung function tests (LFT), echocardiography etc. As a control group for evaluating the prevalence of the AIDs we used all patients with Rheumatoid Arthritis (RA) visiting our clinic between January-December 2005. Data of all RA patients were collected from the electronic database of the hospital. All AIDs mentioned in the discharge diagnoses were recorded. Between-group comparisons were made with the chi-square test for nominal variables and with the independent-sample t-test for numeric variables. Results. 144 patients with SSc were included: 88.8% females, 66.6% with the limited cutaneous subset of disease (lcSSc), mean age 53.9 ± 12.8 years, mean disease duration at study enrollment 5.1±10.5 years and a mean follow-up time of 3.7 ± 2.6 years. Prevalence of the AID in the SSc cohort was 19.4%, patients with lcSSc being more prone to associate other AID (p = 0.001). We noted a tendency towards less interstitial lung disease (p = 0.056) and less digital ulcers (p = 0.081) in patients with SSc and AIDs. Comparing skin involvement for each year of follow-up in patients with SSc with and without and AIDs we observed that the first tended to have lower and more stable values of the mRSS. Conclusion. Patients with SSc and AIDs tend to have a better outcome than the ones without this association. mRSS remains stable across the years in patients with SSc and AID, with lower values than the SSc patients.
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Dissertations / Theses on the topic "AIDS (Disease) – Patients"

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Grove, Teresa. "Nurses' attitudes toward patients with AIDS examined by hours of AIDS education." PDXScholar, 1990. https://pdxscholar.library.pdx.edu/open_access_etds/4071.

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This study was designed to describe the attitudes of staff nurses toward patients who have Acquired Immunodeficiency Syndrome (AIDS), and to determine if the 1989 Washington State licensing requirement for seven hours of AIDS education was effective in changing the attitudes of these nurses toward AIDS patients. Health care providers' attitudes toward patients with AIDS have been documented as differing from their attitudes toward patients with other debilitating conditions (cancer, diabetes, heart disease) in that they place more blame for getting the disease on those with AIDS, they tend to have some degree of homophobia, and they are sometimes overly cautions in using protective procedures around these patients. The consequence of these attitudes can be seen in the nursing care received by some of these patients: insensitive comments and avoidance behavior by staff.
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Walker, Blain S. "The diagnosis and treatment of major depression in AIDS patients : effect of counselor experience and attitude toward people with AIDS." Virtual Press, 1999. http://liblink.bsu.edu/uhtbin/catkey/1137581.

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This study was an investigation into the clinical judgments made by counseling psychologists when faced with a patient who had major depression and AIDS. Two hundred and eighty one counseling psychologists evaluated one of four vignettes depicting an individual with major depression. In three of the vignettes the individual also had AIDS but the vignette varied on how the virus was contracted (unprotected gay sex, IV drug abuse, hemophilia). In the fourth vignette (the control group) the individual did not have AIDS. Results of the study suggested, that the presence of AIDS overshadows the evaluation and treatment decisions made by counseling psychologists when their patient has major depression and AIDS. Three factors-counseling psychologists' general experience with people who have AIDS, their clinical experience with AIDS patients and how the AIDS virus was contracted-were investigated for possible moderating effects of the overshadowing bias. How the AIDS virus was contracted was used as an indirect measure of clinician attitude toward people with AIDS. Neither general or clinical experience with AIDS patients appeared to have an effect on the diagnostic or treatment decisions made by counseling psychologists when evaluating depressed patients with AIDS. As with experience, method of contracting the AIDS virus did not have a moderating effect on the overshadowing bias. Implications of these results for the evaluation and treatment of depression in AIDS patients, as well as future research are discussed.
Department of Counseling Psychology and Guidance Services
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Demling, Jennifer. "Family caregiving for persons with AIDS." Virtual Press, 1995. http://liblink.bsu.edu/uhtbin/catkey/962800.

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This study examines the experience of individuals who participated or did not participate in the caregiving process for a family member who died within approximately the past three years of an AIDS-related illness. The focus of this study is on the adjustment of the caregivers and non-caregivers after the death of the PWA. It was hypothesized that due to their direct involvement in the caregiving process, caregivers would differ significantly from non-caregivers on a number of measures designed to evaluate adjustment. It was hypothesized that caregivers would report better overall adjustment than non-caregivers.Participants completed the Symptom Checklist 90 (SCL-90; Derogatis, Lipman, & Covi, 1973), as well as a semi-structured interview about their experiences. A two-tailed t-test revealed no significant differences between groups. However, effect sizes computed for these variables revealed moderate to large diff ererences between caregivers and non-caregivers on the somatization and interpersonal subscales of the SCL-90. Comparisons to a standardization sample showed that caregivers differed significantly on all subscales from that standardization sample: Non-caregivers differed only on the depression and interpersonal sensitivity subscales. Analysis of the interview data revealed a significant difference in reported stress, with caregivers reporting significantly more stress during the illness of the PWA than non-caregivers. Effect sizes were computed for nine other interview categories; these suggested that caregiversreported substantially less social withdrawal, fewer feelings of guilt, fewer problems resolving issues with the PWA, substantially more physical illness, and more life affirming statements than their non-caregiver counterparts. Several other noteworthy trends that emerged in the interview portion of the study are discussed.Small sample size and pre-existing characteristics of the participants are explored as possible factors affecting the outcome of the study. More controlled studies exploring the adjustment of caregivers and non-caregivers are needed in order to better understand the possible differences that may exist between caregivers and non-caregivers in terms of adjustment after the death of their loved one from an AIDS-related illness.
Department of Psychological Science
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Mlobeli, Regina. "HIV/AIDS Stigma: an investigation into the perspectives and expereinces of people living with HIV/AIDS." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_6069_1189595852.

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People's attitudes towards people living with HIV/AIDS remain a major community challenge. There is a need to generate a climate of understanding, compassion and dignity in which people living with HIV/AIDS (PLWHA) will be able to voluntarily disclose their status and receive the support and respect all people deserve. However, many people expereince discrimination because they have HIV/AIDS. In a certain area in Khayelitsha, a township in Cape Town, a young woman was killed after disclosing the HIV status after being raped by five men. While many previous studies have focused on the external stigma in the general population, there is a dearth of studies on stigma among PLWHA themselves and hence the aim of the present study was to investigate stigma attached to HIV/AIDS from the perspective of PLWHA.

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Hui, Wai-ting. "Serodiagnosis of Penicilliosis marneffei in HIV & non-HIV patients using a recombinant antigen Mp1p." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22029746.

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Baylor, Rita Atkins. "Nurses' attitudes toward caring for patients with AIDS." Virtual Press, 1992. http://liblink.bsu.edu/uhtbin/catkey/845956.

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The main purpose of this study was to examine nurses' attitudes toward caring for patients with Acquired Immune Deficiency Syndrome (AIDS). The study also compared the attitudes of nurses who had cared for AIDS patients with the attitudes of nurses who had not cared for AIDS patients. Educational background was also examined to see if education influences attitudes. The Ajzen-Fishbein Model of Reasoned Action was the framework used for this study.A descriptive design was used for the purpose of gaining more information regarding nurses' attitudes toward caring for patients with AIDS. A random sample of all registered nurses in the state of Indiana was used for this study. The data obtained were analyzed using frequency distributions, independent t-tests, and analysis of variance.Nurses in general are sill uncomfortable with caring for AIDS patients. Between 40% and 50% of nurses are fearful of contracting the AIDS virus and fearful of putting their family at risk. On the other hand, approximately the same percentage are comfortable caring for AIDS patients. Furthermore, nurses believe that health care agencies should care for AIDS patients, but believe that nurses should have the right to refuse to care for AIDS patients.Results of this study indicated that educational background does not influence nurses' attitudes toward caring for patients with AIDS. However, as nurses have more experience caring for patients with AIDS, they appear to develop more positive attitudes.
School of Nursing
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Fourie, Stephanus. "KAPB surveys for HIV/AIDS : a critical review." Thesis, Stellenbosch : Stellenbosch University, 2006. http://hdl.handle.net/10019.1/50617.

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Thesis (MBA)--Stellenbosch University, 2006.
ENGLISH ABSTRACT: HIV/AIDS is one of the most devastating pandemics the world has ever faced. SubSaharan Africa remains the region most affected where more two thirds of the total HIV positive population resides. Despite this region trying to grapple with many negative factors like political unrest, draughts, armed conflict, it now also have to content with HIV/AIDS. HIV/AIDS has already killed ten times more Africans than all of the armed conflicts on the African continent combined (The Washington Quarterly, 2001:191-196). Many of the Sub-Saharan countries are renowned for unemployment and poverty which can be partly be alleviated by economic growth. Studies by Bonnel (2000) concluded that a typical Sub-Saharan country with a 20% HIV/AIDS prevalence rate, would suffer a 2.6% reduction in GDP growth per annum. This indicates that South Africa, where an estimated S.5 million HIV positive people resides (the most in globe) and ever increasing HIV prevalence, is in a serious predicament. There are many interacting variables causing the negative socioeconomic decline. At organisational level direct and indirect costs attributable to HIV, results in a severe decline of profitability and jeopardises sustainable economic activity. Direct costs include costs for medical treatment, health insurance, funeral expenses, retirement and disability and costs to manage HIV in the workplace. Indirect costs include absenteeism and loss of productivity, retraining and recruiting of employees to fill deceased employees' places etc. Although South African organisations acknowledge and predict that HIV/AIDS will have an ever-increasing negative impact on their business, the response to dealing with this issue has been insufficient. The deficient response could be partly ascribed to a lack of guidance, deficient proof of cost effectiveness with no real measurement for the outcomes of intervention programs. This study will critically evaluate a KAPB (knowledge, attitude, perception and behaviour) survey as a second-generation HIV surveillance tool that could address these organisational concerns. KAPB surveys have advantages like providing guidance and increasing cost effectiveness of HIV programs, benchmarking interventions and providing a platform for communication design and feedback to stakeholders. These benefits should motivate organisations to initiate programs that address HIV at an organisational level. KAPB surveys evaluate four employee factors related to HIV - knowledge, attitudes, perception and sexual behaviour. This report will critically evaluate the appropriateness of measuring these factors and some tools used to measure these factors. Further elaboration of the methodology during the execution of a KAPB survey will highlight the current best practices identified in literature. The report will also highlight the obstacles and ways of negotiating them when conducting a KPAB survey. The study will conclude that a well -executed KAPB survey through its many benefits should motivate and assist organisations in designing and implementing HIV/AIDS programs.
AFRIKAANSE OPSOMMING: HIV is een van die ernstigste pandemies wat die wereld al ooit beleef het. Die state in die Sub-Sahara streek is die ergste geaffekteer en meer as twee derdes van die totale HIV positiewe populasie kom in die gebied voor. Die streek wat deurgaans geteister word deur politieke onrus, droogte, oorlog, moet nou ook probeer tred hou met MIV /VIGS. MIV/VIGS het tot op hede alreeds tien keer meer mense gedood as al die oorloë op die Afrika continent saam (The Washington Quarterly, 2001: 191-196). Die meeste van die state in Sub-Sahara word gekenmerk deur werkloosheid en armoede wat deels verlig kan word deur ekonomiese groei. Studies deur Bonnel (2000) het getoon dat die tipiese staat in Sub-Sahara, met 'n 20% MIV insidensie 'n vermindering van tot 2.6% groei in die GDP kan ondervind. Dit voorspel dat Suid-Afrika met 'n voorspelde 5.5 miljoen HIV positiewe inwoners (die meeste in die wereld) ekonomiese noodlot in die oog staar. Daar is verskeie faktore wat saamwerk om die negatiewe ekonomiese 'effek van MIV/VIGS te bewerkstellig. Organisasies se ekonomiese vooruitgang en oorlewing word bedreig deur direkte en indirect kostes van MIV. Direkte kostes wat organisasies moet aangaan sluit in mediese behandeling, mediese fonds bydraes, begrafnis onkostes, aftrede en ongeskiktheidspensioenbetalings. Indirekte kostes sluit in afwesighede, verlies aan produktiwiteit en die heropleiding en werwing van werknemers wat afgestorwe werknemers se plek moet neem. Ten spyte van die feit dat organisasies erken en voorspel dat MIV/VIGS 'n negatiewe impak op die ekonomies welvaart van organisasies sal hê, het weining van die organisasies aksie geneem om die probleem aan te spreek. 'n Moontlike rede vir die onvoldoende aksie kan toegeskryf word aan die tekort aan leiding, bewyse vir kostedoeltreffendheid en geen werklike maatstaf om die programme se resultate te evalueer. Hierdie studie sal KGPG (kennis, gevoelens, persepsie ' en gedrag) studies as 'n tweede generasie MIV opname, krities evalueer. KGPG studies bied verskeie voordele soos om leiding vir HIV programme te bied en verbeterde koste effetiwiteit van MIV programme te bewerkstellig. KGPG studies voorsien ook 'n maatstaf om MIV programme te evalueer en 'n kommunikaise platvorm tussen aandeelhouers. Hierdie voordele sal moontlik organisasies motiveer om aksie te neem en MIV in die organisasie aan te spreek. KGPG studies evalueer vier werknemer faktore met betrekking to MIV /VIGS. Die vier faktore is kennis, gevoelens, persepsie en seksuale gedrag. Die verslag sal die vier faktore krities evalueer vir toepaslikheid en ook fokus op die instrumente wat die faktore evalueer. Aanbevelings sal ook gemaak word ten opsigte van die korrekte en beste metodes wat gevold moet work tydens 'n KGPG studie. Die struikelblokke wat ondervind kan word tydens 'n KGPG studie asook hoe om dit te oorkom sal bespreek word. Die verslag sal bewys dat 'n KGPG studie wat uitgevoer word in Iyn met die beste praktyk baie waarde kan toevoeg tot organisasies ten opsigte van die beplanning en uitvoering van programme om MIV/VIGS te bekamp.
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Gilbert, Hannah. "Rallying resources : strategies of therapeutic engagement among patients living with HIV in Senegal." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=79769.

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In recent years there has been a worldwide recognition of the disparity of HIV treatment available in the West and in Sub-Saharan Africa. The West African nation of Senegal was early to implement measures that allowed for the distribution of highly effective anti-HIV therapy known as Antiretroviral (ARV) therapy to a limited number of patients. This thesis explores how patients living in Senegal who are infected with HIV have engaged in various negotiations to obtain access to treatment and other resources to meet the needs posed by their infection. These negotiations are framed by various historically embedded notions of how to engage relationships in the search for care. Strategies are also shaped by the biopolitically-laden discourse that guides the distribution of ARV therapy. This thesis traces the structure, evolution, and effects of patients' strategic negotiations in response to the introduction of this therapeutic technology.
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Deitcher, Rebecca Ulman. "Health locus of control and HIV : a study of beliefs, attitudes, and high-risk behaviours among homosexual men attending a general medical clinic." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=39806.

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Acquired immunodeficiency syndrome (AIDS) remains an epidemic illness with no known cure. Survival time after infection with the human immunodeficiency virus (HIV), has been lengthened considerably. Rates of new infection among the at-risk male homosexual populations have decreased. Prevention is possible through effective, targeted interventions. This study is an exploration of the role or health locus of control, an individual difference construct from the area of social learning theory, in the maintenance of health-oriented behaviours, co-risk indicative behaviours, and high-risk behaviours in a population of adult male homosexuals attending a general medical clinic. The findings result in distinctly different past histories and present patterns of homosexual behaviours among the two serostatus subpopulations. Low internal expectancy of control over health repeatedly relates in distinctive patterns with the areas of level of happiness, condom usage, and hish-risk sexual behaviours. High internal expectancy of control relates significantly to knowledge-related variables. The physician plays a pivotal role as the source of useful information in this at-risk population. The study population as a whole reports accurate knowledge about HIV and AIDS. The men have reduced high-risk behaviours, increased safer sexual behaviours, and implemented the changes advocated. Serostatus differentiates for many high-risk behavioural patterns. There remains a small core of men among the study participants who continue to participate in high-risk sexual behaviours.
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Klein, Hector Leon. "Pastoral-therapeutic work with family members infected and affected by HIV/AIDS a narrative approach /." Thesis, Pretoria : [s.n.], 2003. http://upetd.up.ac.za/thesis/availabale/etd-08222005-10852/.

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Books on the topic "AIDS (Disease) – Patients"

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David, Miller, Weber Jonathan, Green John, and Canadian Hospital Association, eds. The Management of AIDS patients. Ottawa: Canadian Hospital Association, 1988.

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Stewart, Gail. People with AIDS. San Diego, CA: Lucent Books, 1996.

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Leslie, Mark. Dying with AIDS, living with AIDS. Dorion, Québec: Muses' Company, 1992.

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David, Yelding, Consumers' Association, DSU, and Research Institute for Consumer Affairs., eds. Caring for someone with AIDS. London: Published for the Research Institute for Consumer Affairs by Consumers' Association and Hodder & Stoughton, 1990.

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South African National Council for Child and Family Welfare., ed. AIDS-- a family disease: Initial guidelines. Braamfontein: South African National Council for Child and Family Welfare, 1993.

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Virgilio, Margherita Di, and Ivana Cucco. AIDS: Malattia, prevenzione, assistenza. Milano: FrancoAngeli, 2000.

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Symposium on Topics in Mycology on Mycoses in AIDS Patients (1989 Paris, France). Mycoses in AIDS patients. New York: Plenum Press, 1990.

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Kirkpatrick, Bill. AIDS: Sharing the pain : pastoral guidelines. London: Darton, Longman and Todd, 1988.

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White, Dorothy A., and Jonathan W. M. Gold. Medical management of AIDS patients. Philadelphia, PA: W.B. Saunders, 1992.

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Martell, Dan. AIDS poems. [Port Carling, Ont., Canada]: D. Martell, 1995.

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Book chapters on the topic "AIDS (Disease) – Patients"

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Moulignier, A. "Cerebrovascular Disease in HIV-Infected Patients." In Cardiovascular Disease in AIDS, 131–45. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_10.

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Drouet, L. "Coagulative Disorders in HIV-Infected Patients." In Cardiovascular Disease in AIDS, 169–79. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_13.

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Barbaro, G. "Cardiological Emergencies in HIV-Infected Patients." In Cardiovascular Disease in AIDS, 203–12. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_16.

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Ederhy, S., C. Meuleman, N. Haddour, G. Dufaitre, F. Boccara, and A. Cohen. "Echocardiographic Findings in HIV-Infected Patients." In Cardiovascular Disease in AIDS, 75–84. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_6.

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Mary-Krause, M., and D. Costagliola. "Coronary Heart Disease in HIV-Infected Patients: Epidemiology." In Cardiovascular Disease in AIDS, 99–110. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_8.

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Tabib, A., and R. Loire. "Pathology of Peripheral and Coronary Vessels in AIDS Patients." In Cardiovascular Disease in AIDS, 65–73. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_5.

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Mercié, P., B. Le Bail, and C. Cipriano. "Peripheral Arterial Disease in HIV-Infected Patients: Atherosclerosis and Vasculitic Syndromes." In Cardiovascular Disease in AIDS, 85–92. Milano: Springer Milan, 2005. http://dx.doi.org/10.1007/88-470-0358-x_8.

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Mercié, P., B. Le Bail, and C. Cipriano. "Peripheral Arterial Disease in HIV-Infected Patients: Atherosclerosis and Vasculitic Syndromes." In Cardiovascular Disease in AIDS, 147–55. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_11.

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Garot, J. "Cardiac MRI in Diagnosis of Myocardial Disease in HIV-Infected Patients." In Cardiovascular Disease in AIDS, 85–98. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_7.

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Boccara, F., C. Meuleman, S. Ederhy, S. Lang, S. Janower, A. Cohen, and F. Raoux. "Coronary Artery Disease in HIV-Infected Patients: ClinicalPresentation,Pathophysiology, Prognosis,Prevention,and Treatment." In Cardiovascular Disease in AIDS, 111–29. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-0761-1_9.

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Conference papers on the topic "AIDS (Disease) – Patients"

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Marques, Cristhiane Campos, Fabiana Nunes de Carvalho Mariz, Berenice Moreira, Thaisa Campos Marques, and Carla Nunes de Araújo. "Sexual Behavior and Factors Associated with Syphilis among Patients at a Sexual Health Center." In XIV Congresso da Sociedade Brasileira de DST - X Congresso Brasileiro de AIDS - V Congresso Latino Americano IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/dst-2177-8264-202335s1072.

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Background: Syphilis has resurfaced epidemically worldwide and knowledge of at-risk populations can contribute to disease prevention and control. Objective: To assess the detection rate of syphilis among patients of a sexual health center and its association with sexual and social behaviors. Methods: A cross-sectional study was conducted in the Counselling and Testing Center (CTC) in Rio Verde, Goiás, Brazil. We analyzed retrospective data from standardized CTC forms from patients followed in 2018. Results: A total of 3,526 patient forms were included in the analysis. The number of patients testing positive for syphilis was 344 (9.76%), mostly men (57.56%, p-value [p]=0.0093), more than 8 years of schooling (61.22%, p=0.0017), a tendency to age between 20 and 39 years (63.08%, p=0.0683), and not married (62.07%, p=0.0042). There were no differences between races. Individuals who reported multiple partners (p<0.0001, odds ratio [OR]=0.546), homosexual relationships (p<0.0001, OR=2.931), and use of drugs (p<0.0001, OR=1.291) were more frequently diagnosed with the disease. Men who have sex with men (MSM) tended to not use condoms with steady partners (72.0%, p=0.3257), presented previous sexually transmitted infections (STI) (p=0.0088, OR=2.84), and a higher rate of co-infection with HIV (p=0.0195, OR=2.37). Contradictorily, regular use of condoms and steady partnership were not protective factors (p>0.0500). Conclusions: Data suggest a high detection rate of syphilis among MSM attending the Rio Verde Sexual health center.
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Lefrere, J. J., D. Vittecoq, D. Gozin, and J. Modai. "CIRCULATING ANTICOAGULANT IN AIDS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644859.

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The frequency of a circulating anticoagulant has been reported to be high in AIDS, in particular in case of Pneumocystic carinii pneumonia (Pep). Twenty-five non-hemophiliac patients (23 homosexual males,1 drug addict, 1 tranfused) with AIDS were followed over a six month period. Mean age was 32 (21-42). All patients had a markedly decreased T4/T8 ratio (mean 0.12), a low absolute T4 level (mean : 155/mm3), an elevated total serum immunoglobulins level.Activated partial thromboplastin time (APTT), prothrombintime and thrombin time were measured once a week during hospitalisation. A prolonged APTT (more than 10 seconds as compared to controls) with normal prothrombin time and thrombin time was found only once in 11patients and in two or more occasions in two others.No specific factor level of intrinsic pathway wasfound low enough to explain a prolonged APTT.Evidenceofcirculating anticoagulant (failure to correct aprolonged APTT by equal mixure of normal plasma and patient plasma) was found in all these 13 patients.Nothrombotic or haemorraghic manifestations occured.AIDS manifestations were 2 Pep.1 cytomegalovirus retinitis. 2 Kaposi's sarcomas, 1 Hodgkin's disease, 2 mycobacterium avium intracellulare pulmonary infection, 4 central nervous system toxoplasmosis, 1 Cryptococcus meningitis. Amongst the 12 patients with normal APTT,3_Pcp, 2 cytomegalovirus retinitis. 2 Kaposi's sarcomas, 2 central nervous system toxoplasmosis, 1 unexplained fever, and 2 oesophagus candidiasis were diagnosed. A transiently prolonged APTT associated to a circulating inhibitor seems to be common in AIDS. Weobserved this anomaly in 52 % (13/25). In our five cases of Pcp, 3 had normal APTT. During other opportunistic infections, the circulating inhibitor was found.The similar complications seen in two groups suggest that a circulating anticoagulant is not specifically associated to any opportunistic infection and any malignancybut appearr independently from these circumstances.
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Allen, Rebecca, and Fahad Saeed. "DEVELOPMENT OF TWO DECISION AIDS TO EDUCATE PATIENTS WITH CHRONIC KIDNEY DISEASE: A PATIENT ACCEPTABILITY SURVEY." In 14th International Conference on Education and New Learning Technologies. IATED, 2022. http://dx.doi.org/10.21125/edulearn.2022.1168.

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Desmyter, J. "AIDS 1987." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644751.

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AIDS virus (HIV) transmission by transfusions and blood products has been essentially halted in industrialized countries which haye introduced systematic anti-HIV screening of donations in 1985. New anti-HIV screening assays, based in part on the replacement of disrupted HIV virions by defined DNA recombinant HIV antigens, have improved specificity; sensitivity has been improved as to dectect seroconversion at an earlier stage. Confirmatory assays and (self-)exclusion of risk groups from blood donation do remain mandatory. HIVAg can be detected in some infections before antibody conversion, and HIVAg is more likely to be found in those anti-HIV positives who proceed to disease. However, there is no justification so far for routine parallel HIVAg and anti-HIV screening. There is continued uncertainty how many HIV carriers have not (yet) developed antibody, but their numbers may have been overestimated. Studies to determine how many HIV transmitters have escaped blood bank detection, and why, need to be undertaken in spite of formidable logistic difficulties.The risk of developing AIDS is now estimated at 25-50 % within 10 years after the infectious contact. It is not clear whether the risk should be estimated differently in different groups or persons. In cities in Central Africa, 5-20 % of men and women are confirmed anti-HIV positives. At least 75 % of this HIV carrier rate is due to heterosexual transmission. Heterosexual transmission has been slower in Western countries, but factors precluding slow evolution to high figures by the same route outside Africa have not been identified. Therefore, countries have no choice in advocating behaviour changes in the general population, and not only in the classical risk groups. Initial hesitations toward extended voluntary and confidential screening are dwindling. Well-conceived confidential screening may be the only way to avoid strong-armed government intervention. The latter is certain to be divisive, and is likely to be counterproductive on balance.An efficacious vaccine remains remote, but an antiviral which prolongs life by at least several months in AIDS patients, but not all of them, is now available. Zidovudine (AZT), however, is toxic and mere prolongation of life without cure will impose an additional burden on AIDS economics.A novel virus (HIV-2) has been identified and is already widespread in West-Africans. It causes AIDS, but the present ratio of AIDS cases in those infected seems lower than with HIV(-l); this feature may be transient. HIV-2 antibodies are either detected or missed by anti-HIV-1 screens; if found, they can be distinguished from anti-HIV-1 only by special confirmatory technique. New screening assays showing equal sensitivity for HIV-1 and HIV-2 in a single test should be devised. At present, HIV-2 is very rare in Western countries compared to HIV-1.
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Saeed KADHIM, Nuha, Khulood Abdul Kareem HUSSEIN, and Zainab Salman Dawood SALMAN. "INVESTIGATE THE RELATIONSHIP BETWEEN EPIDEMIC HIV/AIDS VIRUS DISEASE TRANSMISSION AND SPREAD AND HEALTH STAFF KNOWLEDGE AND PRACTICE AT BASRAH TEACHING HOSPITAL IN IRAQ." In VII. INTERNATIONAL SCIENTIFIC CONGRESSOF PURE,APPLIEDANDTECHNOLOGICAL SCIENCES. Rimar Academy, 2023. http://dx.doi.org/10.47832/minarcongress7-7.

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According to recent studies, health professionals still have stigmatizing attitudes toward patients living with HIV/AIDS. Because healthcare workers play an important role in preventing HIV/AIDS transmission, HIV/AIDS education is an important part of improving community health care. The aims of this study are to evaluate practice, examine and describe healthcare personnel's HIV/AIDS knowledge, and attitudes toward people living with HIV/AIDS .This study is a non-experimental descriptive cross-sectional study conducted from December 2021 to February 2022. The samples were collected from health staff (n = 25) is nurses, (n = 25) is midwives, and (n = 25) is technical analyst employed at Basrah Teaching Hospital located in Basrah City, Iraq. A questionnaire include in the 1st part Sociodemographic Characteristics Participant, the majority of participants are female; n = 50 (66.7%), high percentage of high Nursing School students n= 30 (40%) and the majority of healthy staff in each group n = 48 (64%) had no prior training in AIDS prevention methods , In the 2nd part include assessment of healthy staff knowledge of HIV Disease Transmission showed no significant difference (p≤0.05) between the results of nursing, midwifery and technical analyst staff on all items, but the results of the technical analyst staff were better than the results of the other staff. All of the items in the 3rd part of the questionnaire include evaluation of knowledge and practice of Healthy Staff in Hospital Units for HIV/AIDS patients showed no significant difference (p≤0.05) in all of the results between each health staff member. We conclude there was little information among the staff about the mechanism and transmission of the disease. Furthermore, incorrect methods Collection of blood samples , especially ways to draw blood and transfer the sample.
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Matteini, E., C. Pinnetti, F. Frondizi, E. Rando, M. Chiuchiarelli, E. Metafuni, I. Mastrorosa, et al. "OC-60 Time to anti-cancer treatment resumption after SARS-CoV-2 infection in patients with active hematological disease undergoing off-label combined antiviral treatments." In Abstracts from the 16° Italian Conference on AIDS and Antiviral Research. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/sextrans-icar-2024.54.

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Hansen, Laura, Manu O. Platt, Roy L. Sutliff, and Rudolph L. Gleason. "The Mechanical and Structural Changes in Murine Arteries due to the Antiretroviral Drug Azidothymidine (AZT)." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80799.

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With over 33 million people infected with the human immunodefeciency virus (HIV-1), HIV-1 and autoimmune deficiency syndrome (AIDS) is a worldwide epidemic [1]. However, the development and widespread use of highly active antiretroviral therapy (HAART) has helped transform HIV-1 infection from a terminal disease leading to AIDS to a manageable chronic condition. With the increase in life expectancy, a new set of non-AIDS related complications has emerged including dyslipidemia, lipodystrophy, insulin resistance, diabetes mellitus, and cardiovascular disease (CVD) specifically high risks for myocardial infarction[2] and increased incidence of atherosclerosis [3]. Additionally, patients exhibit markers of subclinical atherosclerosis including endothelial dysfunction [4], carotid artery intima-media thickening [5], and arterial stiffening [4, 6].
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Tulio, Robertha, and Rômulo Machado Balmant. "Dental care for HIV positive patients - care and importance - case report." In II INTERNATIONAL SEVEN MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/homeinternationalanais-087.

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Abstract Acquired immunodeficiency syndrome (AIDS) is caused by the "Lentivirus" family of retroviruses, called HIV-1. This syndrome is defined as an infectious disease of viral origin, with its manifestation interspersed in peaks and troughs, with a pathophysiology involving the compromising of the immune system, causing the defense system to not operate correctly, leaving the patient susceptible to the development of infections.
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Matsushita, I., H. Motomura, T. Hiraiwa, S. Arai, C. Ota, and T. Kimura. "AB0357 The support of medical clerks in rheumatic disease clinic aids t2t practice for rheumatologists and improves disease activities of patients with rheumatoid arthritis." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.1618.

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Ciocanel, Alexandra, Razvan Rughinis, and Cosima Rughinis. "DIGITAL TECHNOLOGY AND BOUNDARY WORK IN HOMEOPATHY." In eLSE 2017. Carol I National Defence University Publishing House, 2017. http://dx.doi.org/10.12753/2066-026x-17-250.

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In this paper we examine the evolving roles of digital technology in shaping the professional identity and therapeutic encounters of homeopathic practitioners. Homeopathy is a form of alternative medicine that relies almost exclusively in making a diagnostic on patients’ verbal description of their symptoms. In contrast to the biomedical diagnosis, the homeopathic diagnosis does not place the patient in a disease category, but in a remedy category. The software that aids homeopathic professionals in their practice is based on a digitalization of books that organized the homeopathic knowledge of remedies and symptoms (repertories and Materia Medica). Organized as an inventory of descriptions of remedies and symptoms, the software operates algorithmically in helping the homeopath to match patients’ symptoms to possible remedies and select the most adequate remedy. During the consultation, the homeopath makes a patient file by writing a selection of words extracted from patients’ talk that express symptoms in great detail – including feelings, signs of suffering and various lifestyle preferences. In this process the homeopath and the software co-create the patient’s “person” as a collection of more-or-less idiosyncratic symptoms, in their attempt to match the patient’s symptomatology with the description of one single remedy. Drawing on interviews with patients and homeopaths, observations of consultations and homeopathic seminars, we argue that the use of digital technology is practiced as boundary work. Firstly, digital technology becomes a boundary marker between the patient and the homeopath. Secondly, digital technology helps homeopaths to legitimize their practice as a rigorous one, being one of the strategies used to gain acceptance in the health-care ecosystem. Last but not least, by presenting the software as only a time-saving device, a neutral aide for making “intelligent suggestions” that can be confirmed but also rejected by the homeopath’s judgment, homeopaths create a distinct professional identity oriented around a central principle of their practice: “Treat the patient as a whole person”.
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Reports on the topic "AIDS (Disease) – Patients"

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Zheng, Ruo-xiang, Xun Li, Jing Li, Zhen-wei Liu, Feng Jiang, Nicola Robinson, and Jian-ping Liu. Does Chinese herbal remedy Tangcao tablet work for the treatment of HIV/AIDS：a systematic review of controlled clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0042.

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Review question / Objective: This study aims to evaluate the effectiveness and safety of Tangcao tablet (Tangcao) for treating people with HIV/AIDS. Condition being studied: Acquired immunodeficiency syndrome (AIDS) is a chronic infectious disease characterized by severe immunodeficiency caused by the human immunodeficiency virus (HIV). The infection attacks specifically the white blood cells, CD4+T (CD4) cells, weakening the immunity of individuals against infections such as tuberculosis. Without treatment, patients with AIDS may survive up to 2 years. Pneumocystis pneumonia and infections of the central nervous system are two of the most common causes of death in people with AIDS. AIDS still remains a significant global public health problem, with an estimated 37.7 million people infected with HIV at the end of 2020.
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Haider, Huma. Malaria, HIV and TB in Nigeria: Epidemiology and Disease Control Challenges. Institute of Development Studies (IDS), December 2021. http://dx.doi.org/10.19088/k4d.2022.040.

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Nigeria has the world’s highest number of people affected by malaria and the world’s second largest human immunodeficiency virus (HIV)/AIDS burden. There is a high occurrence of co-infection of malaria in HIV patients (Gumel et al., 2021). Nigeria is also ranked as one of the thirty high tuberculosis (TB) and TB-HIV co-infection burden countries in the world (Odume et al., 2020, 8). Co-infection can make each disease more severe and potentially more infectious (Gumel et al., 2021; Jemikalajah et al., 2021; Chukwuocha et al., 2019). This rapid literature review highlights key aspects of the epidemiology of malaria, HIV and TB in Nigeria, in addition to challenges in controlling the three diseases, in terms of prevention, detection and treatment. This is part of a series of reports looking into Epidemiology of Malaria, human immune deficiency virus (HIV) and tuberculosis (TB) across a set of African Nations.
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Liang, BiYan, BiYan Liang, and Jian Wang. A Meta Analysis of the Efficacy of Tonic Method in Traditional Chinese Medicine for AIDS Immunological Nonresponses. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0077.

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Review question / Objective: To evaluate the efficacy of tonic method in treating AIDS immunological nonresponses. Eligibility criteria: ①Study type: RCT based on tonic method in TCM for AIDS INRs. The language was limited to Chinese and English. ②The research object: HIV/AIDS patients with any disease stage; the intervention objects were adults with no gender restrictions. ③Intervention measures: The treatment group was treated with tonic prescriptions combined with ART, including four types of prescriptions for nourishing qi, nourishing blood, nourishing yin, or nourishing yang; the dosage, frequency, and method were not limited. The control group was treated with ART or mock agent and placebo. ④Outcome indicators: The observation indicators reported in the included studies should include at least one of the following indicators: 1) Effective rate of immune function reconstruction: formulated in accordance with "AIDS (Adult) Chinese Medicine Diagnosis and Treatment Program" (2016 Edition) , effective: CD4 + T lymphocyte counts increased by ≥ 50 cells/l or ≥ 30%, invalid: CD4+ T lymphocyte counts decreased by ≥ 50 cells/l or ≥ 30%; total effective rate = effective number/total number; 2) CD4+T lymphocyte counts level.
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Singh, Ruchi, Akhiya Nail, and Nirendra Kumar Rai. Effectiveness of Vitamin B12 Supplementation on cognitive, motor & mood instability of Parkinson’s disease patients on levodopa treatment :A Systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2023. http://dx.doi.org/10.37766/inplasy2023.2.0066.

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Review question / Objective: The treatment of choice for patients of Parkinson's disease is levodopa. However, levodopa has been suggested to decrease Vit B12 level in these patients. Thus, the research question for this systematic review is whether vit B 12 supplementation in Parkinson's disease(PD) patients on treatment with levodopa improves vit B12 level effecting the Cognition, Motor functions and Mood instability among them in comparison to PD patients on levodopa treatment who are not supplemented with Vit B12. Condition being studied: Parkinson disease is the progressive degeneration of dopaminergic neurons present within the substantia nigra that can lead to altered movements along with the prevalence of cognitive and mood instability as a result of dopamine(neurotransmitter) deficiency. The most effective treatment for the Parkinson's disease is the administration of levodopa, a dopamine precursor . Long term treatment with levodopa causes an increase in homocysteine levels and tissue deficiency of vitamin B12 and folate may occur. Vitamin B12 supplementation is administered as after management regime, in Parkinson patient on levodopa treatment . This study aims to conduct a systematic review, of studies , randomized control trials investigating the ability of vitamin B12 supplementation to enhances the recovery/reduce the decline, if any, of the symptoms of cognitive, motor, mood impairments associated with Parkinson's disease patient on levodopa treatment.
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Li, Ting, Shudan Ge, Wei Zheng, Chao Luan, Xingtong Liu, Zongxiu Luo, Qi Zhao, and Lulu Xie. Effectiveness and safety of panretinal photocoagulation combined with intravitreous ranibizumab for patients with type 2 proliferative diabetic retinopathy：A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0048.

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Review question / Objective: Our study aims to synthesise results from randomised controlled trials to assess the effectiveness and safety of PRP combined with intravitreous ranibizumab for T2PDR. Condition being studied: Diabetic retinopathy (DR) is the most common complication of diabetes mellitus, which will seriously affect the quality of life of patients and bring great burden to patients’ families and society. DR is one of the most important diseases of blindness in people aged 20 to 60 years worldwide. Nearly 15% of diabetic patients with a disease duration of more than 5 years were combined with DR.The prevalence of vision threatening diabetic retinopathy in the United States is 4.4 percent. Worldwide, the prevalence is estimated at 10.2%.At present, the treatment methods for type 2 proliferative diabetic retinopathy (T2PDR), at home and abroad mainly include retinal laser photocoagulation and intravitreal injection of vascular endothelial growth factor (VEGF) inhibitors.
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Krishnamurti, Lakshmanan, Diana Ross, Nitya Bakshi, Cynthia Brown Sinha, and Geoerge Loewenstein. An Online Decision Aid to Help Patients and Caregivers Decide on Treatments for Sickle Cell Disease. Patient-Centered Outcomes Research Institute® (PCORI), January 2020. http://dx.doi.org/10.25302/1.2020.ce.12114318em.

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Delineau, Valeska, Ligia Passos, Ana Rita Ferreira, and Lia Fernandes. The role of behavioral and psychological symptoms of dementia (BPSD) in patient’s autonomy. A scoping review protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0008.

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Review question / Objective: This scoping review study aims to identify, summarize, and appraise available literature regarding the role of (BPSD)/neuropsychiatric symptoms in patients’ autonomy with all types of dementia diagnoses. To accomplish this objective, this scoping review will address the following question: What is the role of behavioral and psychological symptoms of dementia in the patient’s autonomy? This review will comprise the terms capacity, functional abilities, and competence in the autonomy concept. Background: Dementia is a neurodegenerative syndrome characterized by the development of multiple cognitive deficits and behavioral changes that interferes with multiple aspects of life, including cognition, daily functioning, and behavioral. With the progress of the disease, the patients lose their capacity, functional abilities, competence, and autonomy (Barbas & Wilde, 2001; Darby & Dickerson, 2017; Irastorza, Corujo, & Bañuelos, 2011; Lee, Jang, & Chang, 2019; Marson, 2013).
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Anheyer, Melanie, Holger Cramer, Thomas Ostermann, and Dennis Anheyer. Herbal medicine for atopic dermatitis – protocol of a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2023. http://dx.doi.org/10.37766/inplasy2023.4.0041.

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Review question / Objective: To evaluate the effectiveness of topical and systemic herbal medicine in patients with atopic dermatitis. Rationale: Atopic dermatitis is one of the most common skin diseases in both childhood and adulthood (1). Usually, the disease develops within the first year of life. In principle, all skin areas can be affected. However, there are age-dependent predilection sites (2). The diagnosis of atopic dermatitis is made clinically. Children and adults suffer primarily from the excruciating itching (1). As a result, atopic dermatitis not only affects quality of life, but also sleep, school, employment and social environment. The therapy includes a daily basic therapy with emollients. In acute episodes, topical glucocorticoids, in severe courses also systemically administered glucocorticoids or immunomodulators are used (1). Many parents and affected patients additionally use complementary and integrative medicine methods for various reasons (3, 4). Due to the increasing research in this field, an update of existing reviews is highly warranted. Therefore, this review aims to provide an overview of the current state of evidence in the overall field of both, topical and systemic herbal medicine.
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He, zhe, liwei Xing, ming He, yuhuan Sun, jinlong Xu, and rong Zhao. Effect of Acupuncture on Mammary Gland Hyperplasia (MGH): a Bayesian network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0058.

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Review question / Objective: This review aims at conducting a network meta-analysis to assess the potential therapeutic effectiveness and safety of acupuncture therapy for the treatment of MGH. Condition being studied: MGH is a benign breast disease caused by excessive growth of mammary duct epithelial cells and interstitial fibers. Its prevalence rate among women of childbearing age is about 13.5-42%, accounting for 99.3% of the total number of patients with breast related diseases, and its possibility of developing breast cancer can reach 5-10%. Breast hyperplasia can cause clinical symptoms such as breast pain, breast lump, nipple pigmentation and mood fluctuation, which brings severe physical and mental burden to patients. Modern medicine believes that the pathogenesis of MGH is related to sexual hormone disorder secondary to hypothalamus pituitary ovary axis dysfunction.At present, the treatment options of MGH are limited and not completely effective. The commonly used drugs in clinical practice, such as tamoxifen, danazol and goserelin, are expensive, which may lead to breast pain, swelling and increase of interstitial fibrous nodules, and the long-term use of MGH has huge side effects. The clinical guidelines recommend that the use time should be 2 to 6 months. Therefore, it is necessary to seek a treatment method of MGH that is effective, stable and safe.
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Treadwell, Jonathan R., James T. Reston, Benjamin Rouse, Joann Fontanarosa, Neha Patel, and Nikhil K. Mull. Automated-Entry Patient-Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes. Agency for Healthcare Research and Quality (AHRQ), March 2021. http://dx.doi.org/10.23970/ahrqepctb38.

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Background. Automated-entry consumer devices that collect and transmit patient-generated health data (PGHD) are being evaluated as potential tools to aid in the management of chronic diseases. The need exists to evaluate the evidence regarding consumer PGHD technologies, particularly for devices that have not gone through Food and Drug Administration evaluation. Purpose. To summarize the research related to automated-entry consumer health technologies that provide PGHD for the prevention or management of 11 chronic diseases. Methods. The project scope was determined through discussions with Key Informants. We searched MEDLINE and EMBASE (via EMBASE.com), In-Process MEDLINE and PubMed unique content (via PubMed.gov), and the Cochrane Database of Systematic Reviews for systematic reviews or controlled trials. We also searched ClinicalTrials.gov for ongoing studies. We assessed risk of bias and extracted data on health outcomes, surrogate outcomes, usability, sustainability, cost-effectiveness outcomes (quantifying the tradeoffs between health effects and cost), process outcomes, and other characteristics related to PGHD technologies. For isolated effects on health outcomes, we classified the results in one of four categories: (1) likely no effect, (2) unclear, (3) possible positive effect, or (4) likely positive effect. When we categorized the data as “unclear” based solely on health outcomes, we then examined and classified surrogate outcomes for that particular clinical condition. Findings. We identified 114 unique studies that met inclusion criteria. The largest number of studies addressed patients with hypertension (51 studies) and obesity (43 studies). Eighty-four trials used a single PGHD device, 23 used 2 PGHD devices, and the other 7 used 3 or more PGHD devices. Pedometers, blood pressure (BP) monitors, and scales were commonly used in the same studies. Overall, we found a “possible positive effect” of PGHD interventions on health outcomes for coronary artery disease, heart failure, and asthma. For obesity, we rated the health outcomes as unclear, and the surrogate outcomes (body mass index/weight) as likely no effect. For hypertension, we rated the health outcomes as unclear, and the surrogate outcomes (systolic BP/diastolic BP) as possible positive effect. For cardiac arrhythmias or conduction abnormalities we rated the health outcomes as unclear and the surrogate outcome (time to arrhythmia detection) as likely positive effect. The findings were “unclear” regarding PGHD interventions for diabetes prevention, sleep apnea, stroke, Parkinson’s disease, and chronic obstructive pulmonary disease. Most studies did not report harms related to PGHD interventions; the relatively few harms reported were minor and transient, with event rates usually comparable to harms in the control groups. Few studies reported cost-effectiveness analyses, and only for PGHD interventions for hypertension, coronary artery disease, and chronic obstructive pulmonary disease; the findings were variable across different chronic conditions and devices. Patient adherence to PGHD interventions was highly variable across studies, but patient acceptance/satisfaction and usability was generally fair to good. However, device engineers independently evaluated consumer wearable and handheld BP monitors and considered the user experience to be poor, while their assessment of smartphone-based electrocardiogram monitors found the user experience to be good. Student volunteers involved in device usability testing of the Weight Watchers Online app found it well-designed and relatively easy to use. Implications. Multiple randomized controlled trials (RCTs) have evaluated some PGHD technologies (e.g., pedometers, scales, BP monitors), particularly for obesity and hypertension, but health outcomes were generally underreported. We found evidence suggesting a possible positive effect of PGHD interventions on health outcomes for four chronic conditions. Lack of reporting of health outcomes and insufficient statistical power to assess these outcomes were the main reasons for “unclear” ratings. The majority of studies on PGHD technologies still focus on non-health-related outcomes. Future RCTs should focus on measurement of health outcomes. Furthermore, future RCTs should be designed to isolate the effect of the PGHD intervention from other components in a multicomponent intervention.
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