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Kudsi-Zadeh, Chantalle B. "(Re)visualizing AIDS : art activism and the popular medicalscientific image of HIV." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27947.
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This thesis is concerned with AIDS cultural activism. Specifically, it examines artistic responses to the medical/scientific image of HIV that circulates widely in the mainstream press. Examples of AIDS science reporting that focus on the medical/scientific image of HIV are selected from popular American news journals. It is argued that science and journalism are different and mutually dependent domains of knowledge, neither of which can be examined without the other. AIDS activist art engages with the relationship between science and the media and offers alternatives to the authority offered in science reporting. In the author's closing remarks, it is stated that AIDS activist art addresses not only the AIDS crisis but challenges the entire ideological apparatus upon which popular representations of illness are based.
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Boneh, Galia. "Moving from entertainment towards art a new model for creating performance on HIV/AIDS /." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1568127991&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
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Labeodan, Moremi Morire OreOluwapo. "Stochastic analysis of AIDS epidemiology." Thesis, Pretoria : [s.l.], 2009. http://upetd.up.ac.za/thesis/available/etd-10172009-112824.
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Frans, Nocawe R. "ART : the views of counsellors about skills needed in counselling HIV/AIDS patients." Thesis, Link to the online version, 2008. http://etd.sun.ac.za/jspui/handle/10019/1471.
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Nyakwezi, Kamugasha Sheila. "The use of anthropometric indices as an alternative guide to initiating antiretroviral therapy (ART) in children at the Mildmay Centre in Uganda /." Link to the online version, 2008. http://hdl.handle.net/10019/1502.
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Paun, Andrea. "Regulator T cells in murine AIDS." University of Western Australia. Microbiology and Immunology Discipline Group, 2005. http://theses.library.uwa.edu.au/adt-WU2005.0115.
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[Truncated abstract] In the last ten years regulator T (Tr) cells have re-emerged as an integral part of the immune system. Research in this field has rapidly demonstrated the role of these cells in the maintenance of immune homeostasis and their involvement in disease. Tr cells are generated in the thymus as a normal part of the developing immune system. Furthermore, antigen-specific Tr cells are induced in the periphery by a mechanism which is yet to be completely elucidated, but is likely to involve dendritic cells. Tr cells play an important role in autoimmune disease, transplantation tolerance, cancer. Most recently Tr cell involvement has been demonstrated in a growing number of infectious diseases. Tr cell induction was reported in Friend Virus infection at the commencement of this study, and subsequent to publication of our findings have also been identified in FIV and HIV. Murine AIDS (MAIDS) is a fatal chronic retroviral infection induced in susceptible strains of mice by infection with BM5d, a replication defective virus, in a viral mixture which is designated LP-BM5. The manipulation of Tr cells detailed in this thesis and the related publication represent the first reported therapy utilising targeted removal of Tr cells. Chapter 1 summarises the literature relevant to this study up to November 2004. Chapter 2 details the materials and methodologies used in this work. Chapter 3 investigates whether Tr cells are involved in the development of murine AIDS, particularly in the early stages of infection. The data presented in this chapter provides evidence of a population of CD4+ Tr cells which express CD25 on their cell surface and secrete TGF-β, some IL-10 and low levels of IL-4 are induced following infection with LP-BM5. These cells were found to arise by day 12 post infection (pi) by flow cytometry and immunosuppressive cytokine expression was found to peak at day 16 pi indicating a role in the early stages of disease progression. Chapter 4 investigates the effect of therapeutically targeting these induced Tr cells using the antimitotic agent Vinblastine during their induction period. The efficacy of treatment was found to be time dependent and was shown to abrogate disease progression maximally when given at day 14 pi. Treatment with anti-CD4 monoclonal antibody was also found to be efficacious at day 14 pi and confirmed the identity of the Tr cells as being CD4+ T cells. Adoptive transfer studies demonstrated that the return of these cells to a successfully treated host results in renewed MAIDS progression, confirming their role in disease progression
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Spies, Margaretha. "The biopsychosocial factors influencing HIV/AIDS patient adherence to Antiretroviral Therapy (ART) a Social Work study /." Thesis, Pretoria : [s.n.], 2007. http://upetd.up.ac.za/thesis/available/etd-08112008-165506.
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De, Bruto Petro C. "ART-related body composition changes in adult women in a semi-rural South African context." Thesis, Stellenbosch : Stellenbosch University, 2006. http://hdl.handle.net/10019.1/17445.
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Assignment (MPhil)--University of Stellenbosch, 2006.ENGLISH ABSTRACT: The aim of this study was to investigate practical methods of monitoring AIDS related wasting and lipodystrophy in a resource-poor clinical setting with HIV infected women as the population group of interest. Measurement of body composition changes using anthropometry is both cost- and time-efficient. Various different skinfolds were taken and two different equations (the equations of Pollock et al. (1975) and Durnin and Womersley (1974) for calculating body fat were used to determine the most promising method or methods of monitoring body composition changes in a clinical setting. Detailed anthropometric measurements were performed, as well as selected measurements for haematological parameters and quality of life (QoL) for a group of 8 participants on antiretroviral medication (ART group) and 6 participants who were not on treatment (TN group). New variables namely, intra-abdominal indicator (IAI) and a percent of ideal body mass to percent of ideal arm circumference ratio (%IBW:%IAC) were investigated as possible indicators of lipodystrophy. Although measurements were taken at various timepoints, three specific time-points were chosen for data-analysis for the ART group and two time points for the TN group. These three time-points were, baseline (on the day of recruitment for TN participants and within one month before the initiation of treatment for ART participants), short-term (2 to 12 weeks after treatment initiation or the baseline measurement or for the ART and the TN participants) and long-term (within one and a half year of treatment initiation for the ART group). ART and TN participants did not differ for many variables at baseline. The major differences between ART and TN were in measured and derived variables of the arm, especially percent of ideal arm circumference (%IAC) and upper arm fat area (UAFA), which were significantly lower in the ART group. CD4+ and QoL improved significantly for the ART participants from baseline to long-term. This was not associated with changes in muscle mass, but rather some fat mass variables. Participants on antiretroviral medication exhibited changes relating to abdominal obesity. It was concluded that antiretroviral therapy contributed greatly to the QoL of the participants and it probably aided in the recovery from wasting for at least one participant in this study. Measures of the arm can be used in a rural clinical setting to effectively monitor patients with regard to AIDS related wasting. The new variables IAI and %IBW:%IAC could be helpful in the monitoring of lipodystrophy and should be investigated in future research.
AFRIKAANSE OPSOMMING: Die doelwit van hierdie studie is om praktiese metodes te ondersoek om VIGS-verwante uittering en lipodistrofie te meet in ‘n plattelandse kliniese omgewing (waar hulpbronne dikwels beperk is) met MIV ge-infekteerde vroue as populasiegroep. Die gebruik van antropometrie om veranderinge in liggaamssamestelling te meet is beide koste- en tydeffektief. Verskeie velvoumetings is geneem en twee verskillende vergelykings (die vergelykings van Pollock et al. (1975) en Durnin en Womersley (1974)) is gebruik om liggaamsvetinhoud te bereken, met die doel om ‘n belowende metode te vind om veranderinge in liggaamssamestelling te meet in ‘n kliniese omgewing. Verskeie antropometriese metings is geneem, sowel as uitgesoekte hematologiese en lewenskwaliteitmetings (QoL) vir ‘n groep van agt deelnemers wat antiretrovirale medikasie ontvang het (ART groep) en ses deelnemers wat nie hierdie behandeling ontvang het nie (TN groep). Nuwe veranderlikes (binnebuikindikator (IAI) en die verhouding van persentasie van ideale liggaamsmassa tot persentasie van ideale armomtrek (%IBW:%IAC)) is ondersoek as moontlike aanwysers van lipodistrofie. Drie spesifieke tydpunte vir die ART groep en twee tydpunte vir die TN groep is gekies uit die verskeie tydpunte waarby metings geneem is, nl. basislyn (gedefinieer as die dag wat TN deelnemers in die studie opgeneem is en 0 tot 4 weke voor die begin van behandeling vir die ART deelnemers), korttermyn (2 tot 12 weke nadat behandeling begin is of na die basislyn meting) en lang-termyn (binne een en ‘n half jaar nadat behandeling begin is vir die ART groep). By die basislyn tydpunt het min van die ART en TN deelnemers se gemete veranderlikes verskil. Die ART en TN groepe het hoofsaaklik verskil ten opsigte van veranderlikes wat betrekking het op die arm, veral persentasie van ideale armomtrek (%IAC) en bo-arm vetarea (UAFA). Hierdie twee veranderlikes was beduidend laer in die ART groep as in die TN groep. CD4+ seltelling en lewenskwaliteit tellings het beduidend verbeter vir die ART deelnemers van die basislyn tot die lang-termyn tydpunt. Hierdie veranderinge is nie samehangend met veranderinge in spiermassa nie, maar eerder met sommige vetmassa veranderlikes. Deelnemers wat antiretrovirale medikasie ontvang het, het veranderinge getoon wat gedui het op ‘n verhoogde neerlegging van vet in die buikarea. Ten slotte is bevind dat antiretrovirale medikasie bygedra het tot die verbeterde lewenskwaliteit van die deelnemers en dat dit waarskynlik ook die omkeer van uittering van ten minste een deelnemer aangehelp het. Daar is ook bevind dat armverwante metinge gebruik kan word in die plattelandse kliniese omgewing om pasiënte suksesvol te monitor ten opsigte van VIGSverwante uittering. Die nuwe veranderlikes, IAI en %IBW:%IAC kan moontlik gebruik word om lipodistrofie-verwante veranderings te meet en die gebruik van hierdie veranderlikes behoort ondersoek te word in verdere navorsing.
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Parsonson, Ian M. "Syphilis and AIDS historical and social comparisons /." Connect to this title online, 1992. http://tux.lib.deakin.edu.au/adt-VDU/public/adt-VDU20031118.111824/.
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Allen, Annette Marie. "AIDS and Aging: Are the Eldery Becoming the New At-Risk Population?" Thesis, University of North Texas, 1994. https://digital.library.unt.edu/ark:/67531/metadc278037/.
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This dissertation breaks new ground. It examines the perceptions of older adults towards AIDS prevention. Using the National Health Interview Survey, 1988: AIDS Knowledge and Attitudes Supplement, a modified Health Belief Model is developed. Despite the low number of older adults 55+ with AIDS, some extenuating circumstances increase their risk of AIDS contraction. Older adults have lower levels of knowledge about AIDS, weaker immune systems and receive more blood transfusions. Societal influences include educational neglect at the hands of physicians, healthcare workers and social service personnel. The first stage of the dissertation involved establishing older adults as an at-risk population through an extensive literature review. Next, the data was described utilizing frequencies, correlations and factor analysis. Frequencies clearly indicated that older adults in the data set had low levels of AIDS knowledge and did not view themselves at risk for AIDS contraction. Correlations between the variables were minimal. A modified Health Belief Model was developed and tested. Multiple regression determined that minimal variation in the two dependent variables, "Perceived Effectiveness of Effective Methods to Prevent AIDS Contraction" and "Perceived Effectiveness of Ineffective Methods to Prevent AIDS Contraction" was accounted for by the independent variables. Although F ratios allowed rejection of the two null hypotheses, beta weights were low. Adjusted R^2's accounted for only 21% and 16% respectively of the variation in the dependent variables. Finally, discrepancies in the model were determined and recommendations made for further research. Most health belief models concentrate on individual social-psychological variables. Due to AIDS' societal consequences, it is proposed that societal providers of education: physicians, social service workers and healthcare personnel need to be included in the model. Recommendations were made for additional research into sexual behavior of older adults and exploration of available training of physicians, healthcare and social service professionals. Finally, recommendations were made to provide training and education for both professionals as well as the elderly to prevent their growth into an at-risk population.
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Brinkman, Lynn M. "From Apartheid to HIV/AIDS: The Construction of Memory, Identity, and Communication Through Public Murals in South Africa." Bowling Green, Ohio : Bowling Green State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1174923130.
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Chinkubala, Lontia. "To investigate the extent to which under-five HIV positive children access Antiretroviral Therapy (ART) : a case of Siavonga District of Southern Province of Zambia." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/97087.
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Thesis (MPhil)--Stellenbosch University, 2015.ENGLISH ABSTRACT: The impact of HIV/AIDS has affected all categories of people in society, including children under the age of five. This segment of the population depends entirely on adults and older children in order for them to survive. This research endeavoured to investigate the extent to which under-five HIV positive children access ART in Siavonga District in the Southern Province of Zambia. The necessity of such information for all cannot be over-emphasised as this category of the population under study is among the most neglected when it comes to issues of HIV/AIDS. Under-five HIV positive children need special attention in order for them to enjoy their right to survival and development. In terms of methodology, the research took an interpretive approach as it employed the qualitative methodology in its endeavours, in order to get an in-depth understanding of people’s views on the topic under research. Different interview schedules were used to collect data from community members, Community Health Workers (CHW), Home-based Care Providers (HBCP), staff of the Ministry of Health and District AIDS Task Force (DATF). The findings of this research addressed all the objectives but one. This research revealed that almost all the community members in Siavonga District had general knowledge about HIV/AIDS and the need for under-five HIV positive children accessing antiretroviral therapy. However, their attitudes and practices varied when it came to the application of this knowledge. According to respondents, the major challenges that under-five HIV positive children were facing when it came to accessing ART were as follows: food insecurity, followed by access to health facilities and social matters. Others included stigma and discrimination, long distances to health facilities, inadequate disposable income at household level and negative attitudes by some people who think that it is a waste of time and resources to give too much attention, including ART to under-five HIV positive children whom according to them will die soon. However, the majority of respondents indicated that there was need to accept these children like any other as they too had the right to live; hence, they needed care and support which included facilitating their access to ART. This research was an eye opener to all duty bearers to recognize and acknowledge the importance of under-five HIV positive children’s access to ART. This will contribute towards enhancing the will to step up efforts for this intervention. From the findings, it is evident that there is need for income generating activities to provide disposable income to people of Siavonga District so that they give appropriate support, particularly to children who are infected or affected by HIV/AIDS. Furthermore, more resources are required from NGOs, government and other stakeholders to enhance not only sensitization on the importance of the target population’s access to ART, but also provision of these ART services. All relevant stakeholders should heed the call to aggregate information for under-five HIV positive children in question so as to specially target interventions accordingly.
AFRIKAANSE OPSOMMING: Die impak van MIV/Vigs raak alle kategoriee van mense in die samelewing, insluitende kinders jonger as vyf jaar oud. Die segment van die bevolking is heeltemal afhanklik van volwassenes en ouer kinders om te oorleef. Hierdie navorsing poog om die omvang van kinders jonger as vyf, wie MIV positief is, se toegang tot antiretrovirale terapie (ART) in die Siavonga Distrik van die suidelike provinsie van Zambia te ondersoek. Die noodsaaklikheid van sodanige inligting vir alle sektore in die samelewing kan nie oorbeklemtoon word nie, aangesien hierdie kategorie van die bevolking een van die mees verwaarloosde is wanneer dit kom by MIV/Vigs verwante kwessies. Kinders jonger as vyf wie MIV positief is, moet spesiale aandag ontvang sodat hulle reg op oorlewing en ontwikkeling kan geskied. In terme van die metodologie het die navorsing ‘n beskrywende benadering gevolg om die kwalitatiewe metode in sy poging, ten einde ‘n in-diepte begrip van mense se standpunte oor die onderwerp onder navorsing te kry. Verskillende onderhoude is gebruik om data in te samel van gemeenskapslede, gesondheidswerkers in die gemenskap, tuisversorgers, personeel van die Ministerie van Gesondheid en Distriks vigs-taakspan. Die bevindinge van hierdie navorsing het al die doelwitte, behalwe een, aangespreek. Die navorsing het getoon dat byna al die gemeenskapslede in Siavonga Distrik algemene kennis het oor MIV/Vigs en die behoefte van kinders jonger as vyf se toegang tot ART. Hul houdings en praktyke verskil egter in die toepassing van hierdie kennis. Volgens die respondente is die grootste uitdagings wat kinders jonger as vyf ondervind wanneer dit kom by toegang tot ART is voedselonsekerheid, gevolg deur toegang tot gesondheidsfasiliteite en sosiale aangeleenthede. Ander sluit in stigma, diskriminasie, lang afstande na gesondheidsfasiliteite, onvoldoende besteebare inkomste op huishoudelike vlak en negatiewe houdings van sommige mense wat dink dat dit ‘n vermorsing van tyd en hulpbronne is om aan kinders jonger as vyf te spandeer, aangesien, die kinders in elk geval (volgens hulle) binnekort sal sterf.Die meerderheid van die respondente het aangedui dat dit nodig is om hierdie kinders soos enige ander kind te aanvaar en dat hulle ook die reg het om te leef: daarom dat hulle sorg en ondersteuning benodig, wat die fasilitering van hul toegang tot ART insluit. Hierdie navorsing het weer die klem geplaas op die belangrikheid van kinders jonger as vyf se toegang tot ART. Dit is duidelik dat daar ‘n behoefte is aan inkomste-genererende aktiwiteite en om besteebare inkomste aan die mense van Siavonga Distrik te voorsien, sodat hulle toepaslike ondersteuning kan bied, veral aan kinders wat deur MIV/Vigs geraak word. Verder is meer hulpbronne nodig van nie-regeringsorganisasies, die regering en ander belanghebbendes, nie net om die belangrikheid van die teikenbevolking se toegang tot ART nie, maar ook vir voorsiening van hierdie ATR dienste.
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Klunklin, Areewan. "Thai women's experiences of HIV/AIDS in the rural north : a grounded theory study /." View thesis, 2001. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20031126.122457/index.html.
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Thesis (PhD) -- University of Western Sydney, 2001."Thesis submitted for the degree of Doctor of Philosophy, University of Western Sydney, School of Nursing, Family and Community Studies." Bibliography: leaves 219-254.
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Nyakwezi, Sheila. "The use of anthropometric indices as an alternative guide to initiating antiretroviral therapy (ART) in children at the Mildmay Centre in Uganda." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/2434.
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Thesis (MNutr (Interdisciplinary Health Sciences. Human Nutrition))--Stellenbosch University, 2008.Introduction: More than half a million children worldwide die from the Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) each year. In Uganda, HIV/AIDS is a major cause of infant and childhood mortality. Although the government of Uganda, through various strategies, has increased access to antiretroviral drugs (ARVs), resulting in national scaling up of accessibility to antiretroviral therapy (ART), initiation of ART in resource-limited areas remains a challenge due to constraints such as the absence of or limited number of CD4 machines and related laboratory constraints. Further scaling up of ART for children would be greatly strengthened by increased access to laboratory services for CD4 counts or the introduction of alternative indicators or guidelines for the initiation of ART. Aim: This study therefore set out to investigate, through the analysis of retrospectively collected data, whether anthropometric indices (wasting - weight for height; underweight - weight for age; and stunting - height for age) could provide a useful alternative guide when deciding about initiation of ART in children aged 2-12 years in the absence of sophisticated clinical and laboratory support. Methods: The study was conducted at the Mildmay Centre, an HIV/AIDS specialist centre located in Kampala, Uganda. Parameters such as the age at which children had been initiated onto ART, duration on ART, World Health Organisation (WHO) and Centre for Disease Control (CDC) disease stages at time of initiation, anthropometry at time of initiation, CD4% staging at time of initiation, support received from food aid programmes, referral to other health centres as a result of malnutrition and care-giver nutrition education/counselling were all determined retrospectively from clinical records. Results: It was found, based on CDC (2000) growth reference charts, that of the total number of children who took part in this study (N=125), 98.4% were mildly wasted, 52.8% mildly underweight and 75.2% mildly stunted when they were initiated onto ART. Of the children, who had WHO disease staging documented - 40% (N=50), the majority - 86% (N=43) were in WHO disease staging II and III during initiation of ART. and 96% (N=48) were mildly wasted. However, the relationship between WHO disease staging and wasting, underweight, and stunting at initiation of ART in children at the Mildmay centre was not significant. The relationship between CD4% and underweight or stunted children was also not significant. It was established however, that in the absence of CD4 laboratory parameters (since CD4% is vital in the initiation of ART in children) as is the case in resource limited areas, anthropometric indices (moderate to severe wasting, weight for height -W/H) could be used concurrently with CDC and WHO disease staging to initiate ART in children. However, it is important to note that anthropometric indices on their own cannot be used as a guide for initiating ART in children. Conclusion: Anthropometric status alone cannot be used to accurately determine when to initiate ART in children 2-12 years.
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Gray, Sally Suzette Clelland School of Art History & Theory UNSW. "There's always more: the art of David McDiarmid." Awarded by:University of New South Wales. School of Art History and Theory, 2006. http://handle.unsw.edu.au/1959.4/32495.
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This thesis argues that the work of the artist David McDiarmid is to be read as an enactment of late twentieth century gay male and queer politics. It will analyse how both the idea and the cultural specificity of ???America??? impacted on the work of this Australian artist resident in New York from 1979 to 1987. The thesis examines how African American music, The Beats, notions of ???hip??? and ???cool???, street art and graffiti, the underground dance club Paradise Garage, street cruising and gay male urban culture influenced the sensibility and the materiality of the artist???s work. McDiarmid???s cultural practice of dress and adornment, it is proposed, forms an essential part of his creative oeuvre and of the ???queer worldmaking??? which is the driver of his creative achievements. The thesis proposes that McDiarmid was a Proto-queer artist before the politics of queer emerged in the 1980s and that his work, including his own life-as-art practices of dress and adornment, enact a mobile rather than fixed gay male identity.
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Bundschuh, Molly Ellen. "Cowboys, “Queers,” and Community: the AIDS Crisis in Houston and Dallas, 1981-1996." Thesis, University of North Texas, 2014. https://digital.library.unt.edu/ark:/67531/metadc699956/.
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This thesis examines the response to the AIDS crisis in Houston and Dallas, two cities in Texas with the most established gay communities highest number of AIDS incidences. Devoting particular attention to the struggles of the Texas’ gay men, this work analyzes the roadblocks to equal and compassionate care for AIDS, including access to affordable treatment, medical insurance, and the closure of the nation’s first AIDS hospital. In addition, this thesis describes the ways in which the peculiar nature of AIDS as an illness transformed the public perception of sickness and infection. This work contributes to the growing study of gay and lesbian history by exploring the transformative effects of AIDS on the gay community in Texas, a location often forgotten within the context of the AIDS epidemic.
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Moratioa, Gugulethu. "Psychosocial factors that affect adherence to antiretroviral therapy amongst HIV/AIDS patients at Kalafong hospital." Diss., Pretoria : [s.n.], 2008. http://upetd.up.ac.za/thesis/available/etd-08052008-122226.
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Oizumi, Joelle J. (Joelle Julienne). "Magical Contagion and AIDS Scale: Development and Validation." Thesis, University of North Texas, 1994. https://digital.library.unt.edu/ark:/67531/metadc500468/.
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A Magical Contagion and AIDS Scale was developed to address problems with existing Contagion and AIDS measures. Magical Contagion is an influence that exists after contact is terminated. It is comprised of Permanence, Holographic Effects, Moral Germ Conflation and Backward Action. Data from 280 undergraduates revealed low mean levels of Magical Contagion and AIDS. Contagion effects did not differ on demographic variables. Content validity, criterion-related validity, discriminate validity, and internal consistency were evaluated. Significant correlations were found between the Contagion Scale and Merging/Separation and Homophobia Scales. Negative correlations were found between the Contagion scale and the AIDS knowledge and social desirability scales. Alpha reliabilities were high (a > .93) for the Contagion scale and subscales. Factor analysis suggested the existence of a single factor and mixed support for three factors.
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Seesholtz, John Clayton. "An introduction to the AIDS quilt songbook and its uncollected works." Thesis, connect to online resource, 2009. http://digital.library.unt.edu/ark:/67531/metadc12199.
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Lim, Andrew Yih-Fan. "Mechanisms of immune regulation in HIV disease." University of Western Australia. School of Surgery and Pathology, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0081.
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[Truncated abstract] HIV infection compromises the ability of the host to mount effective immune responses. In untreated HIV disease, immune activation drives high rates of cell turnover and apoptosis, ultimately leading to abnormal and dysregulated cellular function. Immune activation may also induce the expansion of CD4+ regulatory T (Treg) cell populations capable of suppressing anti-HIV responses. Treatment with antiretroviral therapy (ART) allows the recovery of CD4+ T cell numbers in most patients. Persistent deficiencies in the number and function of CD4+ T cells seen in a proportion of individuals may reflect elevated numbers of Treg cells or an imbalanced regulatory-to-effector cytokine milieu. Furthermore, some patients develop paradoxical illnesses associated with the recovery of cellular function, known as immune restoration disease (IRD). The first part of this thesis addresses the role of CD4+ Treg cells in untreated and treated HIV disease. The second part addresses the phenotype of immune cells that express IL-10 and its receptor in untreated and treated patients, and the role of IL-10 in mycobacterial IRD. Firstly, several cell surface markers were evaluated to find a flow cytometry assay that could be used routinely to identify CD4+ Treg cells in HIV-infected patients. I tested CD25, GITR, CTLA-4, NRP-1 and LAG-3, but their expression did not mirror the expression of FoxP3, an intracellular transcription factor specific to CD4+ Treg cells (Chapter 2). Two published studies then described the use of CD127 to identify CD4+FoxP3+ Treg cells in humans. Using CD127, I determined the proportions and numbers of CD4+ Treg cells in untreated HIV-infected patients and in patients in their first year of ART. Proportions of CD4+ Treg cells correlated with the proportions of activated (HLA-DRHI) CD4+ T cells and with plasma HIV RNA levels in untreated patients, but showed an inverse correlation with CD4+ T cell count. In both untreated and treated patients, the proportions and numbers of FoxP3+ cells that expressed CD8 were significantly higher than in uninfected donors. This was clearest in patients with CD4+ T cell counts below 300/'L (Chapter 3). This body of work suggests that the frequencies of CD4+ Treg cells are directly related to the level of HIV-associated immune activation. Phenotyping of FoxP3+CD4+ Treg cells in untreated and treated patients and in uninfected donors revealed that co-expression of CD45RO, CD28, CTLA-4 and markers of activation were similar in all HIV-infected patients and controls. ii FoxP3+CD8+ T cells exhibit lower levels of CD45RO, CD28 and CTLA-4, but higher expression of PD-1 and CD57 (Chapter 4). This suggests that FoxP3+CD8+ T cells may have a reduced functional capacity. It is unclear whether they have regulatory activity by virtue of FoxP3 expression. ... Both patients produced higher levels of IFN? compared with IL-10 in response to mycobacterial antigens. In contrast, patients who experienced uneventful immune reconstitution produced higher levels of IL-10 (Chapter 6). Part 1 of this thesis highlights the importance of using specific cellular markers to identify CD4+ Treg cells, and confirms CD127 as a valuable marker for routine monitoring of blood Treg cells. Part 2 of this thesis demonstrates the important regulatory role of IL-10 in patients receiving ART.
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Larichiuta, Inez S. "What are the issues and challenges for the nursing profession with regard to HIV/AIDS?" Instructions for remote access. Click here to access this electronic resource. Access available to Kutztown University faculty, staff, and students only, 1991. http://www.kutztown.edu/library/services/remote_access.asp.
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Thesis (M.P.A.)--Kutztown University of Pennsylvania, 1991.Source: Masters Abstracts International, Volume: 45-06, page: 2948. Abstract precedes thesis as 6 preliminary leaves. Typescript. Includes bibliographical references.
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Roman, Gail Sandra. "An exploration of the stigma experienced by women who are living with HIV/AIDS." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_1255_1210750809.
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The effects of the spread of HIV/AIDS place a great burden on women and children, who will probably suffer most in terms of social and economic deprivation. Since HIV/AIDS is linked to social taboos such as sexuality, drug use and death, there are enormous levels of ignorance, denial, fear and intolerance in most communities. These prejudices lead to the stigmatisation and discrimination of people who are living with HIV/AIDS. Moreover the illness, as it is sexually transmitted, has been conflated with sexual excess, lack of morals, and those already stigmatised such as sex workers with associated discourses of blame, shame and guilt. Generally, responses to HIV and those living with HIV have served to reflect, legitimise and reproduce broader social inequalities on the basis of sexual orientation, gender, race and class. Stigma is the reason why many people who are living with HIV/AIDS, choose not to disclose their status and seek apposite assistance. This study explored the stigma experienced by a group of women who are living with HIV/AIDS and to develop a deeper understanding of whether these experiences are complicated by social responses.
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Winnubst, K. D. (Kimberly Dawn). "University Students, Knowledge of AIDS, Perceived Susceptibility to AIDS, and Their Sexual Behaviors." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc500840/.
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A random sample of 365 students attending a university in northern Texas returned a mailed questionnaire measuring the students' knowledge of Acquired Immuno-Deficiency Syndrome (AIDS), their perceived susceptibility to AIDS, and their sexual practices during the last year. The students had high knowledge levels about AIDS in general. However, 70% did not worry about getting AIDS. Collectively, there was a display of concern until it became a personal issue. The students (59%) saw themselves as less likely than most people to get AIDS. Although 70% of this sexually active group did not use condoms, they still did not perceive themselves as susceptible to AIDS.
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Medlen, Kim Stanley. "Deliberate masquerades: socialised stigma, HIV/AIDS and altered gay male body image." Thesis, Curtin University, 2010. http://hdl.handle.net/20.500.11937/824.
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Three themes are developed in this exegesis. Firstly, it discusses the conceptual base that informs the creative outcomes of this research. This centres on homo-sexuality, disease, illness and the deliberate masquerades that are often under-taken by HIV-positive Australian homosexual males as a response to socialised stigma. Through these masquerades, they enhance the physicality of their bodies so as to conform to Western cultural perceptions of masculine and healthy body ideals and thus avoid stigma that would otherwise be placed on them. This exploration draws upon theories from sociology to discuss these physical enhancements with an emphasis on the period since the onset of HIV/AIDS in the early 1980s. Secondly, it explores the works of visual artists that comment on the HIV/AIDS pandemic prior to the mid 1990s when no effective long-term treatments were available. Thirdly, it investigates HIV/AIDS-based art produced since the mid 1990s, after long-term treatments became available, and discusses how this work contrasts with the earlier works. Also discussed are the parallels and differences between the body of work that is supported by this exegesis and these other contemporary artworks that address HIV/AIDS issues.
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Elkins, Tamara L. (Tamara Lynn). "Psychosocial and Spiritual Factors Affecting Persons Living with HIV and AIDS." Thesis, University of North Texas, 1993. https://digital.library.unt.edu/ark:/67531/metadc277960/.
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The purposes of this study were (a) to examine whether social support decreases as the person with HIV disease progresses from asymptomatic HIV to symptomatic AIDS and (b) to examine the extent to which general well-being might be mediated through a religious and/or spiritual support system.
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Wang, Ya-Chien. "AIDS Preventative Behavior Among Taiwanese University Students." Thesis, University of North Texas, 1997. https://digital.library.unt.edu/ark:/67531/metadc279286/.
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This study used the Health Belief Model to examine the predictors of AIDS preventive behavior. The independent variables were the variables of individual perception, modifying factors (psychological variables), and likelihood variables. The respondents, the Taiwanese students of the University of North Texas, were influenced both by Chinese sexuality and Western values in their AIDS-risk behavior. The results revealed that 90% of the respondents were misinformed on the availability of AIDS vaccine. In addition, a majority of the students were either abstaining from sex or practicing monogamy. Using Pearson's correlation coefficient and multiple regression analysis, this study found that the psychological variables rather than cognitive variables significantly influenced the respondents' AIDS preventive behavior. Finally, suggestions were made for future research on AIDS, and for AIDS preventive behavior campaigns.
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Bloodgood, Martha Madden. "High-Risk Sexual Behaviors of Young Adults: AIDS Prevention." Thesis, University of North Texas, 1994. https://digital.library.unt.edu/ark:/67531/metadc277878/.
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The Health Belief Model was used to study HIV/AIDS beliefs of 419, 18 to 24 year old, never married, sexually active, heterosexual college students and predict their AIDS preventive behaviors from a larger sample of 662 college students. The structural properties of the scales used were evaluated using confirmatory factor analysis. Recent preventive behaviors were predicted in a LISREL Structural Equation Modeling analysis.
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Henschel, Peter W. (Peter William). "Stigma and Attributions of Blame toward Persons with AIDS (PWAs)." Thesis, University of North Texas, 1996. https://digital.library.unt.edu/ark:/67531/metadc278400/.
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A sample of 227 undergraduate students was administered pre-intervention paper-and-pencil questionnaires to assess homophobia, fear of AIDS contagion, symbolic representations of AIDS and homosexuality, and specific personality attributes including authoritarianism, religiosity, and conservatism. Participants then read one of eight intervention vignettes about an ill person; these vignettes varied by sexual orientation of the patient, disease (AIDS versus lung cancer), and mode of transmission (in the AIDS conditions). Participants then completed post-intervention measures assessing the degree to which the ill person in the vignette was responsible and to blame for his illness, the level of stigma toward him, and concerns about social interactions with him. Results indicate the following: a) Attributions of personal responsibility are primarily a function of mode of illness transmission; b) fear of AIDS contagion is predictive of stigma and social avoidance of PWAs; and c) AIDS-related stigma and attributions of blame are largely a function of symbolic associations between homosexuality and IV drug abuse (which were previously stigmatized) and AIDS.
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Van, der Zel Dirk Willem. "The extent to which employers are implementing the Code of Good Practice on HIV/AIDS, as it relates to the Employment Equity and Labour Relations Acts." Diss., Pretoria : [S.n.], 2004. http://upetd.up.ac.za/thesis/available/etd-09122005-151129/.
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Munro, Ian. "The lived experience of gay men caring for others with HIV/AIDS living, loving, and dying in the era of HIV/AIDS /." Connect to this title online, 2002. http://tux.lib.deakin.edu.au/adt-VDU/public/adt-VDU20020913.150027/.
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Irungu, Purity Nduta. "Networks and narratives an exploration of their relationship and potential for understanding the actual experiences of women with HIV/AIDS /." Connect to thesis, 2006. http://portal.ecu.edu.au/adt-public/adt-ECU2006.0040.html.
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Pardee, Mirella Guerra. "The Iconology of Suffering: Providing a Locus of Control for the Victim in Early Modern Italy." Bowling Green State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1237490158.
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Yang, Victor. "Unleashing power : pathways to inclusion and representation in U.S. AIDS activist organisations : a comparative case study of political representation in the AIDS Coalition to Unleash Power (ACT UP)." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:5b51086e-cd00-4d92-b39a-2865219ea5a1.
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The thesis proposes a theory for the development of substantive representation among social movement organisations (SMOs). Substantive representation (SR) is the extent to which political institutions advance the policy interests of their constituents, in particular the most disenfranchised. Despite their noble proclamations, institutions of representative democracy often fail to advance the interests of groups who have been ignored and absent at the proverbial table. The thesis establishes a causal process to explain the divergence in SR outcomes among informal SMOs, or all-volunteer groups that disavow formal hierarchy in favour of egalitarian modes of decision-making. It utilises a case study of the AIDS Coalition to Unleash Power (ACT UP), an umbrella organisation dedicated to ending the HIV/AIDS crisis in the United States and worldwide. It explains an anomalous story of SR attainment through the ACT UP Philadelphia chapter, compared to sister groups in New York City and Boston. The analysis draws from 92 semi-structured interviews, 13 months of participant observation, periodical review, and archival databases. ACT UP Philadelphia translated common SMO intentions of inclusivity into the uncommon rituals of practice. It forged a deliberate pipeline to invest not only in the presence but also the power of disenfranchised people with HIV, people too dark and poor to interest counterpart groups in other cities. Through an analytic retelling of ACT UP's history, the thesis argues that the fulfilment of SR depends on the ability of SMOs to appeal to member self-interest. Critically, SMOs can offer material incentives and nurture feelings of debt and obligation: causal steps to recruitment and sustainability of a heterogeneous membership. In building a crucial if contentious core of dissimilar people and partnerships, SMOs can unleash an oft-unrealised power for collective action and SR, by and for disenfranchised peoples who had thought change to be impossible.
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Iyiani, Christian, and n/a. "A case study of HIV/AIDS prevention in Nigeria : assessment and recommendations." University of Otago. Department of Social Work and Community Development, 2008. http://adt.otago.ac.nz./public/adt-NZDU20080213.112805.
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This is a two-stage study of HIV/AIDS prevention. In Stage One, the study examines the HIV/AIDS approach of Western aid organisations (INGOs) and compares it to the lived realities of people who are most 'at risk', sex workers, unemployed street youth, and married low income families, in the poor migrant community of Ajegunle in Nigeria�s Lagos state. The study found that INGOs and their client NGOs emphasised Western medical models of HIV/AIDS for both intervention (e.g. testing and ARV drugs for management) and prevention (e.g. through education and behaviour change).
In contrast, among 'at-risk' groups, the study revealed a high degree of knowledge about the transmission of HIV/AIDS (contrary to Western medical assumptions), but also detected strong feelings of powerlessness in being able to address it. INGOs and their client organisations were operating at the levels of tertiary or curative and secondary or behaviour change prevention, whereas the views of the local 'at-risk people' indicated relevance of the primary prevention level, the social structural conditions of the people.
In analysing the results of the first stage of the study, the findings identified a process of 'talking past each other' by official aid agencies and those most at risk, thereby inhibiting effective prevention. The INGOs and NGOs used their financial power, based on the gross inequality in the world distribution of resources, to dictate their own agendas, omitting primary intervention and instead concentrating on secondary and tertiary prevention. The study suggests that new thinking about multi-sectoral responses with full community participation is necessary in order to engage in more effective preventive action.
The study then sought out alternative sources of power that might permit that to happen, notably the strengths of the local Ajegunle community. As a poor community, they lacked financial resources and human capital, such as skilled workers, but they had significant knowledge capital about their own circumstances and the realities people faced. The community also had considerable cultural capital and local organisations with considerable relational capital around community links, broad based support and commitment to such action.
This analysis suggests the need to identify and work through the power differentials using community development processes, especially seeking to empower local communities to take part in decision-making over prevention, if effective action is to take place. The process required is one of a negotiated, inclusive partnerships for sharing information, experience, and decision-making, involving all the relevant stakeholders - the International Organisations (INGOs), National NGOs, Community Groups and the community itself.
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Muwanguzi, Samuel. "The glocalization and acculturation of HIV/AIDS: The role of communication in the control and prevention of the epidemic in Uganda." Thesis, University of North Texas, 2005. https://digital.library.unt.edu/ark:/67531/metadc4949/.
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Grounded in the social constructivism tradition, this study examined the role of communication in the glocalization and acculturation of HIV/AIDS by a section of sexually active Ugandans then living in Rakai district during the advent of the epidemic in 1982. Sixty-four women and men participated in ten focus group discussions in Rakai and Kampala districts. Five themes emerged from the data highlighting how individuals and communities made sense of the epidemic, the omnipresence of death, how they understood the HIV/AIDS campaign, and how they are currently coping with its backlash. The study concludes that HIV/AIDS is socially constructed and can be understood better from local perspectives rather than from a globalized view. The study emphasizes the integration of cultural idiosyncrasies in any health communication campaigns to realize behavioral change.
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Gunn, Paul W. (Paul Wayne). "AIDS and Higher Education in Texas: Policies at Accredited Institutions." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc332547/.
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This study of all of the post secondary institutions accredited by the Commission on Colleges of the Southern Association of Colleges and Schools which were located in Texas determined the number that had policies regarding persons with AIDS. The study determined how long policies had been in effect and analyzed policies in order to determine commonalities and differences. An additional purpose was to examine relationships between five major variables and 18 topics which were identified as being issues likely to be addressed in institutional AIDS policies.
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Sorrells, David J. "The Evolution of AIDS as Subject Matter in Select American Dramas." Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2600/.
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Dramatic works from America with AIDS as subject matter have evolved over the past twenty years. In the early 1980s, dramas like Larry Kramer's The Normal Heart, William Hoffman's As Is, and Robert Chesley's Night Sweat educated primarily homosexual men about AIDS, its causes, and its effects on the gay community while combating the dominant discourse promoted by the media, government, and medical establishments that AIDS was either unimportant because it affected primarily the homosexual population or because it was attributed to lack of personal responsibility. By the mid-eighties and early nineties, playwrights Terrence McNally (Love! Valour! Compassion!)and Paul Rudnick (Jeffrey)concentrated on relationships between sero-discordant homosexual couples. McNally's "Andre's Mother" and Lips Together, Teeth Apart explored how families and friends face the loss of a loved one to AIDS. Tony Kushner's Pulitzer Prize-winning Angels in America epic represents living beyond AIDS as a powerful force. Without change and progress, Angels warns, life stagnates. Angels also introduces the powerful drugs that help alleviate the symptoms of AIDS. AIDS is the centerpiece of the epic, and AIDS and homosexuality are inextricably blended in the play. Rent, the Pulitzer Prize-winning musical by Jonathan Larson, features characters from an assortment of ethnic and social backgrounds - including heterosexuals, homosexuals, bi-sexuals, some with AIDS, some AIDS-free, some drug users - all living through the diverse troubles visited upon them at the turn of the millennium in the East Village of New York City. AIDS is not treated as "special," nor are people with AIDS pandered to. Instead, the characters take what life gives them, and they live fully, because there is "no day but today" ("Finale"). Rent's audiences are as varied as the American population, because it portrays metaphorically what so many Americans face daily - not AIDS per se, but other difficult life problems, including self-alienation. As such, Rent defies the dominant discourse because the community portrayed in Rent is the American community.
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Nikisi, Joseph. "Access to antiretroviral treatment in the public sector, in Zambia." Diss., Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-04282009-163207.
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Ndawula, Barnabas. "Criminalisation of HIV/AIDS in South Africa: a critical look at the Criminal Law (Sexual offences and related matters) Amendment Act 32 of 2007." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/1280.
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Human Immuno Virus (HIV) and Acquired Immuno Deficiency Syndrome (AIDS) have formed part of the South African landscape since the first report in 19831and today South Africa is reported to be the country with the highest number of people living with HIV/AIDS in the World2. This state of affairs, in combination with South Africa’s high sexual crime rate resulted in a general public out-cry with calls for the government and the legislature to enact laws to stem the spread of HIV/AIDS3. Government and the legislature finally responded by way of promulgating the criminal law (sexual Offences and related matters) Amendment Act4 (hereinafter the sexual Offences Act). The Sexual Offences Act inter alia provides for the compulsory testing of alleged offenders of sexual crimes5 This treatise will show that chapter five of the sexual Offences Act, indirectly criminalises HIV/AIDS, and that this is not desirable. It will be submitted that the criminalisation of HIV is against the stated UNAIDS policy 6 It is finally submitted in this treatise that South Africa should repeal all provisions in its law that directly or indirectly criminalises HIV/AIDS transmission and instead follow both and is a deterrent to public health methods of curbing the epidemic, while at the same time exacerbates the spread of the epidemic by forcing people who are HIV positive not to openly come out. It will be argued in the use of criminal law against the transmission of HIV creates stigma and is also an attack on individual human rights. The study will also show that the supposed marginalised persons, such as women and children are not protected by the use of criminal law in the prevention of HIV transmission, contrary to the arguments of the proponents of those who support the use of criminal law. The study will show that far from protecting these marginalised groups of people, criminalisation of HIV transmission, does in fact hurt them the UNAIDS policy and the South African development corporation (SADC) Model Law on HIV and AIDS.
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Henderson, Kenya Y. Kemp. "Race Differences in Religiosity, Social Support, and Quality of Life among People Living with HIV/AIDS in Dallas/ Ft. Worth, TX." Thesis, University of North Texas, 2011. https://digital.library.unt.edu/ark:/67531/metadc84214/.
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This study examines race differences and the relationship between religiosity/ spirituality and social support on quality of life (QOL) among people living with HIV/AIDS in Dallas/Ft. Worth, TX. The data were obtained from the Project VOICES research study conducted by the Center of Psychosocial Health Research at University of North Texas in 2003. This study explores the hypotheses that religiosity/spirituality and social support positively influences quality of life among people living with HIV/AIDS. The current study uses a diverse, gender-balanced sample consisting of African Americans (n = 156), aged 20-68, 47% male, 52% female and 1% transgendered) and Non-African Americans (n = 131), aged 19-65, 50% male, 46% female and 3% transgendered) (Caucasian, Latino, & others) to evaluate the relationship among variables of interest. Multiple regression analyses revealed that social support was a significant factor explaining quality of life (QOL) for African Americans when controlling for medical variables but did not for non-African Americans. Religiosity/spirituality was not found to be significant in this study. The implications of the findings are discussed.
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Onyebuchi, Iroezindu Michael. "Prevalence of HIV-related opportunistic diseases amongst HAART patients at the Federal Medical Centre in Owerri, Nigeria." Thesis, University of the Western Cape, 2012. http://hdl.handle.net/11394/5200.
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Magister Public Health - MPHBackground: The hallmark of HIV infection is immunosuppression which predisposes to unusual infections and malignancies generally known as opportunistic diseases (ODs). Globally, ODs are the major cause of morbidity and mortality in people living with HIV (PLHIV). Since the advent of Highly Active Antiretroviral Therapy (HAART), a significant decline in AIDS progression and ODs has been observed globally. However, most of the evidence suggesting sustained decline in AIDS progression and ODs has come from high-income settings with relatively less burden of ODs in the pre-HAART era. The findings of studies in high-income settings may not be generalizable to resource-limited settings. Lack of information regarding the burden of ODs in HAART-experienced populations in Nigeria and the risk factors for their occurrence has made it difficult to fully assess the sustained efficacy of HAART in the country. The aim of this study was to investigate the prevalence of and risk factors for HIV-related opportunistic diseases amongst HAART patients at the Federal Medical Centre (FMC) in Owerri, Nigeria. Study design and setting: A quantitative, cross-sectional descriptive and analytical study was conducted with 354 adult HIV-infected patients 15 years and above, who were on HAART for a minimum of 12 weeks at the HIV clinic of the FMC, Owerri, South-east Nigeria. Patients currently manifesting an OD whose onset ante-dated the commencement of HAART were excluded. The participants were recruited by simple random sampling. Data collection: Using a structured questionnaire, data was collected by clinicians through interviews, physical and laboratory examinations for patients that provided informed consent and met the study criteria. The questionnaire captured patient’s socio-demographic information and other relevant clinical/laboratory data. Data Analysis: The data was analysed using Epi info version 3.5.1 and Open Epi Version 2.2.1. Descriptive statistics for HIV-related ODs were carried out using percentages and frequencies tables for categorical variables and means (SD) or medians (IQR) for numerical variables. In univariate analysis, the Chi-square test was used to determine significance of association between OD and socio-demographic and clinical variables while the Student "t"-test was used to compare group means. Logistic regression model (multivariate analysis) was used to determine the independent risk factors for the occurrence of ODs using parameters that had a p-value of <0.25 on univariate analysis. All reported p-values <0.05 were considered statistically significant. Results: The mean age of the participants was 41.1 ± 10.0 years; and females were in the majority (65.8%). Over 40% of them were rural dwellers, 50.4% belonged to the lower socioeconomic class, and 55% had a monthly household income less than 20,000 Naira. Fifty percent (50%) of them had advanced immunosuppression at first presentation. The median duration of HAART (3 years) paralleled the median duration of HIV diagnosis (3.4 years) and HAART adherence rate was 78%. The overall prevalence of ODs was found to be 22.4%. Among the 76 patients diagnosed with ODs, the leading conditions were candidiasis (38.2%), TB (34.2%), dermatitis (25%), chronic diarrhoea (6.6%) and sepsis (6.6%). The independent risk factors for the occurrence of ODs were household income less than 20,000 Naira (Adjusted odds ratio [AOR] = 2.4, 95% CI 1.1-5.1), HIV duration of less than 3 years (AOR= 2.1, 95% CI 1.1- 4.2), advanced WHO clinical stage at baseline (AOR= 8.1, 95% CI 4.0-16.4), baseline haemoglobin less than 10 g/dl (AOR= 2.9, 95% CI 1.3-56.1), current CD4 cell count less than 200 cells/μl (AOR= 3.0, 95% CI 1.14-6.2), and HAART non-adherence (AOR= 5.4, 95% CI 2.6-11.2). Past history of TB was found to be a strong predictor of TB (AOR= 5.3, 95% CI 1.4-20.2). Conclusions: Opportunistic diseases are common in patients receiving HAART in Nigeria and candidiasis and TB remain the leading conditions. Late presentation and HAART non-adherence are among the strongest risk factors for ODs in patients receiving HAART. Others include duration of HIV diagnosis less than 3 years, presence of anaemia at the time of first presentation and having a low CD4 cell count while on HAART. Beyond these clinical risk factors, poverty increases the risk of developing an OD during HAART and may emerge a strong determinant of HIV-related ODs in developing countries. Recommendations: A high index of suspicion for ODs remains necessary in HAART patients. Health education on HIV screening and early presentation should be intensified. PLHIV who are anaemic before commencement of HAART, those with low CD4 cell count despite HAART use, and low-income earners should become target groups for a more aggressive evaluation for ODs. Prophylaxis for TB and fungal infections in the absence of active disease should be widely implemented in developing countries. HAART adherence should be intensified.
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Chiapa, Ana Luz. "The Relationships among Perception of Stigma, Ethnic Identity, and Acculturation in People Living with HIV/AIDS." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5293/.
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The HIV/AIDS epidemic continues to grow and minorities have been affected at a disproportionate rate. Two factors that are hypothesized to be associated with HIV/AIDS stigma include ethnic identity and acculturation. The current study uses a diverse, gender-balanced sample (n= 201, aged 23-68) of African-Americans (54.2%), European Americans (31.8%), and Latinos/Hispanics (10%) to evaluate the relationship among the proposed variables. The study found that higher levels of ethnic identity and other group orientation were associated with lower levels of perceived HIV/AIDS stigma. A stepwise linear regression analysis (adjusted R2 = .13, F(11, 189) = 3.74, p < .001) revealed that as the level of inclusiveness of other ethnic groups (t = -4.263, p < .001) increases, the level of perceived HIV/AIDS stigma decreases. The results from this study suggest that the development of interventions that address stigma and inclusiveness of other ethnic groups may benefit people living with HIV/AIDS.
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Ranucci, Melissa B. "Positive and Negative Affect: Differential Impact of Optimism, Pessimism, and Coping in People Living with HIV/AIDS." Thesis, University of North Texas, 2005. https://digital.library.unt.edu/ark:/67531/metadc4804/.
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People living with HIV/AIDS (PLH) struggle with depression. Recent research suggests that depression affects medical regimen adherence, disease progression, and risky sexual behaviors. The present study uses a stress and coping theory viewing HIV-related stigma and physical symptoms as stressors in PLH. Results suggest whereas symptoms and stigma consistently predict negative affect, positive affect, and overall depression, the role of optimism, pessimism, active coping, denial, and behavioral disengagement is not as clear. Pessimism and denial predict negative affect and depression. Optimism and behavioral disengagement predict depression and positive affect. Active coping only predicts positive affect. Focusing on positive and negative affect as distinct components that contribute to overall depression may help researchers develop interventions more effectively.
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Bradshaw, Joe W. "Condom Use Among College Students." Thesis, University of North Texas, 2001. https://digital.library.unt.edu/ark:/67531/metadc2852/.
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With the spread of the Human Immuno-Deficiency Virus and sexually transmitted diseases, it is extremely important for sexually active individuals to protect themselves properly if they decide to engage in sexual intercourse. Knowledge of HIV and the Acquired Immune Deficiency Syndrome has been associated with safer sexual practices, but knowledge alone does not totally explain risky sexual practices. This study examined how 154 college students' knowledge of HIV/AIDS, relationship status, perceptions of condom use, and perceptions of personal risk affect condom use during sexual intercourse. The impact of trust and love justifications along with the approval of peers were also examined. Perceptions of condom use and perceptions of personal risk were compared by gender and ethnicity; how perception of personal risk is related to condom use and condom use intentions was also examined. Condom use intention was found to be a significant predictor of condom use, and a significant difference of means for condom use intentions was reported between individuals who used condoms during their last experience with sexual intercourse and those who did not use condoms during their last sexual experience
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Boulvain, Thibault. "L' art en sida : les représentations de la séropositivité et du sida dans l'art américain et européen, 1981-1997." Thesis, Paris 1, 2017. http://www.theses.fr/2017PA01H040.
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Jusqu'en art, la crise du sida est un tournant majeur de l'histoire contemporaine. Cette étude couvre la période allant de ses origines à la révolution thérapeutique (trithérapies) de la fin des années 1990, et s'intéresse à son impact sur les artistes américains et européens et leurs œuvres. Ceux-ci, sur la question, ont trop rarement été regardés ensemble, et pourtant: de Cindy Sherman à Derek Jarman, de Niki de Saint Phalle à Jeff Kaons, de Gilbert & George à Jenny Holzer, de Michel Journiac à David Wojnarowicz, on repère le même saisissement dans les représentations, qui ne pouvaient alors plus être les mêmes, et pour cause. Y est en effet passé tout ce qui travaillait profondément les sociétés occidentales au temps de l'épidémie, et d'abord le pire d'elles-mêmes qui se défoulait dans un espace social considérablement abîmé par la crise épidémique. Les images s'en souviennent, comme des forces de résistance qui lui furent opposées, et de la volonté intraitable de n'y rien céder, de sortir par tous les moyens d'une situation bloquée. Structuré en quatre parties ("l''esprit de catastrophe" ; "Les corps de la maladie" ; "Violence exaspérée" ; "L'esprit de communauté"), qui correspondent chacune à une entrée dans l'époque et dans la crise du sida, à une hypothèse les concernant, L'art en sida ... envisage la possibilité d'écrire une histoire de la maladie à partir des très nombreuses représentations qui la firent autant qu'elles ont été provoquées par elleThe AIDS crisis was a major turning point of contemporary history. This work, which begins with the start of the epidemic and ends with the medicinal revolution that was triple therapy, at the end of the 1990's, focuses on the impact of AIDS on - and in the works - of American and European artists. These artists have rarely been considered together through the lens of the virus, and yet Cindy Sherman, Derek Jarman, Niki de Saint Phalle, Jeff Kaons, Gilbert & George, Jenny Holzer, Michel Journiac and David Wojnarowicz - they are ail seized by same need to represent this crisis, at a time when no representation could truly be unaffected. In these works of arts, the undercurrents of western societies - starting with the bleakest - could be made current. These images could act as a memorial, like an emblem of resistance to that which would oppose them, and as beacon of indomitable will to never give up, and to try and find a way out of a deadlock. Centred on four main parts (« The Spirit of Catastrophe» ; « Bodies of Sickness »; « Frustrated Violence » ; « Community Spirit »), which each correspond to a window into the aids crisis, four proposals are put forward in order to comprehend the artistic output of the period. Art in AIDS puts forward the possibility that the works produced at the time of the disease are as much an integral part of the history of the disease than they are a consequence of it
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Wentworth, Glen S. "Leading selected members of First Baptist Church, Krotz Springs, Louisiana, in implementing a strategy for ministering to persons who are HIV positive." Theological Research Exchange Network (TREN), 1993. http://www.tren.com.
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Reynolds, Carol A. (Carol Ann). "Attitudes of Nursing Faculty Toward Patients With AIDS and Patients With a Homosexual Lifestyle." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc332811/.
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The purposes of this study were (1) to determine whether patients with AIDS are stigmatized by nursing faculty, (2) to determine whether practicing homosexuals are stigmatized by nursing faculty, (3) to determine whether faculty attitudes toward AIDS patients are influenced by the patients' sexual preference, and (4) to determine whether faculty attitudes toward practicing homosexual patients are influenced by the patients' disease. This study is a modified replication of studies by Kelly et al.
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Myburgh, Hanlie. "Treatment through empowerment? : exploring the dynamics of ‘responsibility’ in antiretroviral therapy (ART) in two clinics in the Cape Winelands." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/79969.
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Thesis (MA)--Stellenbosch University, 2013.ENGLISH ABSTRACT: This study investigates how the new technology of treatment, i.e. antiretroviral therapy (ART), is incorporated into public health care institutions. The success of this technology ideally relies on the notion of the ‘responsibilised’ patient as one who, simply put, consistently maintains the level of ARV-adherence necessary to suppress the viral load and to avoid drug resistance. The stringent management and continual monitoring of treatment adherence necessary to achieve these outcomes lie beyond the direct control of the health care institution. Given that the institution sees its patients irregularly, a patient’s divergence from treatment guidelines is established only after the fact. The institution takes on a supporting role while it is the patient who, on a day-to-day, dose-by-dose basis manages and monitors themselves, making ART a seemingly individual endeavour and responsibility. This shift in responsibility is compatible with the ‘new contract’ between provider and client, necessitated by ART. Even so, the institution attempts to manipulate the day-to-day behaviours of the patient to conform to those required in order to achieve treatment outcomes. This thesis examines how these different aspects of ART play out within two clinics in the Cape Winelands, and more specifically, the institutional intricacies of managing a disease which requires treatment that is not directly observed.
AFRIKAANSE OPSOMMING: Die studie ondersoek hoe die nuwe tegnologie van behandeling, antiretrovirale behandeling (ARB), in publieke gesondheidsorgklinieke geïntegreer word. Die sukses van hierdie tegnologie hang af van die nosie van die ‘verantwoordelike’ pasiënt wat, eenvoudig gestel, die nodige vlak ARV-gebruik handhaaf om die virale lading te onderdruk en weerstand te voorkom. Die streng kontrole oor die toewyding tot behandeling wat nodig is om hierdie uitkomstes te bereik, lê buite die direkte beheer van die gesondheidsorgkliniek. Aangesien die kliniek sy pasiënte slegs periodiek sien, word ʼn pasiënt se afwyking van behandelingsriglyne eers later gemeet. In hierdie opsig neem die kliniek 'n ondersteunende rol in, terwyl dit die pasiënte is wat op 'n daaglikse, dosis-tot-dosis basis hulself moet handhaaf en monitor. Dit maak ARB 'n oënskynlike individuele onderneming en verantwoordelikheid. Hierdie skuif in verantwoordelikheid is in lyn met die nuwe kontrak tussen die gesondheidsorgdiens en die kliënt, wat deur ARB genoodsaak word. In ieder geval probeer die institusie om die daaglikse gedrag van die pasiënt te manipuleer om te pas by die riglyne wat deur die uitkomstes genoodsaak word. Hierdie tesis ondersoek hoe hierdie verskillende aspekte van ARB binne twee klinieke in die Kaapse Wynland uitspeel, en meer spesifiek, die institusionele bestuur van 'n siekte waarvoor behandeling nie direk geobserveer kan word nie.
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Tilton, Abigail C. "The health status of people living with HIV/AIDS and in treatment in the United States." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5339/.
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Vulnerable populations comprise a growing number of people living with HIV/AIDS and are at increased risk for poorer health outcomes. The purpose of this research was to approximate the effect of the Ryan White CARE Act on the health status of people living with HIV/AIDS who were receiving medical care in the United States. The vulnerable populations model was utilized to identify appropriate variables for analysis as well as to provide a sequencing for the testing of models. Data analyzed in this study came from the 1996 Baseline Survey of the HIV Cost and Services Utilization Study (HCSUS), a cooperative study between RAND and the Agency for Health Care Policy and Research (now known as the Agency for Health Care Quality and Research). Three analyses sequences, using different dependent variables, to estimate health status were conducted. In the first analysis, health status was measured by CD-4 count and stage of illness. In the second analysis, only CD-4 counts were used for health status. In the final analysis, health status was estimated based on AIDS diagnosis. Each of the three analyses included the same independent variables: race, gender, education, sexual orientation, income, insurance status, region of the country, receipt of case management, perceived health, and level of antiviral therapy. The three analyses suggested similar results. Specifically, that African Americans and women had better health status as compared to whites and men, respectively. Additionally, insurance, case management, and antiviral therapy were associated with poorer health status. Factors such as education, income, and region of the country yielded inconsistent results between models. To better understand the effect of the Ryan White CARE Act on health outcomes for people living with HIV/AIDS, future research should consider inclusion of a variable that more directly measures the CARE Act, such as payer source for medical care.
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Thomazeau, Romain. "Du sida aux cendres : entre guerre culturelles et guerre biologique : représenter (dans) la crise du sida." Thesis, Paris 1, 2018. http://www.theses.fr/2018PA01H310/document.
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La crise du sida n'est pas derrière nous, même si l'incendie semble éteint, les cendres elles, restent. Premièrement, parce que l'épidémie n'est nullement endiguée, mais aussi parce que nous continuons d'être hantés par les représentations, les discours, les constructions et les significations que cette pandémie transporte avec elle. Le sida est un phénomène complexe, tenter de le comprendre, c'est faire face en premier lieu à des séries de mots, d'images médiatiquement puissantes qui supplantent d'autres réalités. Pour parvenir à percer cette pandémie, il faut pouvoir en étudier tous les aspects, et parmi ces facettes, l'art a joué un rôle prépondérant dans la crise du sida, notamment parce qu'il a été particulièrement utilisé pour signifier une partie de ces autres réalités cachées. Dans ce travail de recherche, quatre axes se sont dessinés qui parcourent un large spectre des questions posées par le sida et ses représentations, autant, que les enjeux d'expositions, de médiatisation, de discursivité ou encore de significations que cette épidémie contemporaine sans précédent a mis en exergue. Le sida a révélé de nombreux problèmes dans nos sociétés occidentales, sans pour autant qu'ils soient aujourd'hui circonscrits. L'art a joué un rôle majeur dans la prise de conscience durant ces trente-cinq dernières années, en produisant des images et des contres-images. L'art a permis de contre-représenter une réalité qui de par nos sociétés de pouvoirs nous était tue, il a donné une voix à ce qui reste toujours une épidémie silencieuse et stigmatisante. Représenter (dans) la crise du sida a donc été et est toujours un combat, si ce n'est une forme de guerre culturelleThe AIDS crisis is not behind us, even if the fire seems to be extinguished, the ashes remain. First, because the epidemic is by no means contained, but also because we continue to be haunted by the representations, discourses, constructions and meanings that this pandemic carries with it. AIDS is a complex phenomenon, trying to understand it, is the deal first with a series of words, images that are media-intensive, which supplant other realities. To achieve to break this pandemic, we must be able to study ail aspects, among these facets, art has played a leading role in the AIDS crisis, especially because it has been particularly used to signify those other hidden realities. ln this research, four axes have emerged that cover a broad spectrum of questions posed by AIDS and its representations, as much as the stakes of exhibitions, media coverage, discursivity or meanings that this unprecedented contemporary epidemic has highlighted. AIDS revealed many problems in our Western societies, without, however, being circumscribed by now. Art has played a major role in raising awareness over the past thirty-five years by making images and counters-images. Art has allowed to counter-represent a realité which through our societies of power, was silent to us, it gave a voice to what always remains a silent and stigmatizing epidemic. Representing (in) the AIDS crisis has therefore been and still is a struggle, if not a form of cultural war