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Journal articles on the topic 'Aggressiveness profile'

Author: Grafiati

Published: 22 July 2023

Last updated: 31 July 2025

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1

Ruiz-Esteban, Cecilia, Inmaculada Méndez, Juan Pedro Martínez-Ramón, Nuria Antón-Ros, and Nelly Gromiria Lagos San Martín. "Profiles of Aggressiveness and Stress in Spanish Adolescents." European Journal of Investigation in Health, Psychology and Education 15, no. 6 (2025): 112. https://doi.org/10.3390/ejihpe15060112.

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Aggressiveness among schoolchildren can be shaped by specific school-related situations that elicit stress. Accordingly, this study aimed to identify differentiated profiles of secondary school students based on the levels of aggressive behavior they exhibit. A further objective was to examine whether various stress-related factors differ significantly across these behavioral profiles. The sample consisted of 386 secondary school students (M = 13.73; SD = 1.14), of whom 52.6% were female. Data were collected using the Aggression Questionnaire (AQ) by Buss and Perry and the School Situation Sur

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Yasniar, Maharani, and Ferry Irawan. "The influence of financial distress, board gender diversity, and CEO profile on tax aggressiveness." Educoretax 5, no. 3 (2025): 396–417. https://doi.org/10.54957/educoretax.v5i3.1453.

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This research is a quantitative study that aims to determine the effect of financial distress, board gender diversity, and CEO profile on tax aggressiveness. This research uses secondary data in the form of financial reports and annual reports of energy sector companies listed on the Indonesia Stock Exchange for the period 2019-2023. A total of 110 observation data was collected from 22 sample companies. Hypothesis testing uses panel data regression analysis with the help of STATA software at a significant level of 5%. The results of tests indicate that (1) financial distress has a negative ef

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Burian, Rosemarie Anne, Tobias Appenzeller, Philipp Oertle, et al. "Nanomechanical profiling of human breast tumors as prognostic marker for breast cancer." Journal of Clinical Oncology 35, no. 15_suppl (2017): 11618. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.11618.

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11618 Background: Assessment of tumor aggressiveness is crucial when making treatment decisions. Established prognostic markers may be insufficient to stratify cancer patients into treatment relevant risk groups. Emerging evidence indicates mechanical properties of cancer cells and their microenvironment play a vital role in cancer invasion and metastases. Detecting and measuring these nanomechanical changes could be a marker of cancer aggressiveness. Methods: We developed an atomic force microscope (AFM) based method: ARTIDIS (Automated and Reliable Tissue Diagnostics) for measuring nanomecha

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Rasskazova, E. "Latent personality profiles in mental illnesses: analysis of restructured clinical scales of MMPI-2." V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY, no. 1 (May 15, 2019): 52–60. http://dx.doi.org/10.31363/2313-7053-2019-1-52-60.

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On a sample of 262 patients with mental illnesses based on restructured clinical scales of MMPI-2 six latent personality profiles were identified. A “suppressive” profile is characterized by a tendency toward self-presentation, suppression, and is more common with adaptation disorder and schizophrenia. The “normative” profile can be combined with aggressiveness, difficulties of behavior control and is typical for every second patient with addictions. The “psychopathized” profile is haracterized by a nonspecific increase in psychopathological complaints and is common in depressions. The “neurot

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Boussaidi, Ahmed, and Mounira Sidhom Hamed. "The Impact of Governance Mechanisms on Tax Aggressiveness: Empirical Evidence from Tunisian Context." Journal of Asian Business Strategy 5, no. 1 (2015): 1–12. http://dx.doi.org/10.18488/journal.1006/2015.5.1/1006.1.1.12.

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Research on the tax side occupied the stage center during the last decade. Several researchers have attempted to study the different effects of some options such as tax aggressiveness on firms and individuals. Overall, tax aggressiveness affects negatively the longevity of companies but what remains unanswered is by what specific means corporate governance decreases tax aggressiveness activities. In this paper, we examine the effect of some governance mechanisms on corporate tax aggressiveness. The study is based on the analysis of a sample of Tunisian listed firms over the 2006-2012 periods.

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Giusca, Simona Eliza, Elena Corina Andriescu, Irina Draga Caruntu, and Delia Ciobanu. "Clinicopathological Profile of Medullary Thyroid Carcinoma—Could We Predict Aggressive Behavior?" Biomedicines 11, no. 1 (2023): 116. http://dx.doi.org/10.3390/biomedicines11010116.

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Medullary thyroid carcinoma (MTC) accounts for only 2–5% of all thyroid malignancies. Clinical and pathological characteristics alone may suffice to predict outcomes, but unstable behavior in some cases suggests that other factors may influence a worse course of the disease. This study aims to identify criteria that could predict increased aggressiveness. We analyzed 59 consecutive MTC cases. We focused on the relationships among clinicopathological characteristics, parameters of aggressiveness (extrathyroidal extension, lymphovascular invasion, and lymph node metastasis), and parameters for M

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Escalante, Hugo Jair, Esaú Villatoro-Tello, Sara E. Garza, A. Pastor López-Monroy, Manuel Montes-y-Gómez, and Luis Villaseñor-Pineda. "Early detection of deception and aggressiveness using profile-based representations." Expert Systems with Applications 89 (December 2017): 99–111. http://dx.doi.org/10.1016/j.eswa.2017.07.040.

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Sobchik, L. N., B. A. Spasennikov, and S. V. Kulakova. "Criminological Aspects of Aggression." Psychology and Law 12, no. 1 (2022): 209–25. http://dx.doi.org/10.17759/psylaw.2022120116.

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The results of a retrospective study of groups of convicts with varying degrees of aggressive behavior show the possibilities of the Standardized Multifactorial Personality Research Method (SMIL, the Russian version of MMPI), the interpretive approach of which is based on the one created by L.N. Sobchik theory of leading trends in assessing the degree of aggressiveness corresponding to the severity of the committed act. The leading tendencies, according to the average profiles of SMIL, are determined: among "hooligans" impulsivity with weakly expressed aggressiveness and unformed self-control;

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Obminski, Zbigniew, Helena Mroczkowska, Marina Jagiello, and Artur Litwiniuk. "Sex-and sport related differences in the personality traits students in volleyball, basketball and judo athletes." Physical education of students 24, no. 6 (2020): 304–11. http://dx.doi.org/10.15561/20755279.2020.0601.

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Background and Study Aim. Psychology is a very important field of knowledge in every area of human life, and personality and temperament have a large impact on the quality of human life, including mental and physical health, and indirectly on the results achieved in elite sport. The purpose of the study was to verify the assumption that there are differences in the psychological profile of professional sportsman students depending on the gender and type of sports discipline. Material and methods. The research covered athletes of both sexes belonging to academic sports clubs practicing vo

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Khajah, Maitham A., Sarah Khushaish, and Yunus Luqmani. "Lactate Is a Major Promotor of Breast Cancer Cell Aggressiveness." Cancers 17, no. 11 (2025): 1793. https://doi.org/10.3390/cancers17111793.

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Background: Lactate dehydrogenase (LDH) activity, producing high levels of lactate from pyruvate in cancer cells, is often associated with poor patient prognosis. We previously showed enhanced LDH/lactate levels in estrogen receptor (ER) compared to ER + breast cancer cells; lactate or pyruvate supplementation to ER + cells significantly enhanced their motile ability, while LDHB gene knockout (KO) or treatment with LDH inhibitors reduced the motility of the highly aggressive ER breast cancer cells. Aims: To investigate the molecular mechanisms by which lactate, LDHB KO, or treatment with LDH i

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Waro, Mochammad Choirul, and Alifiati Fitrikasari. "Profile of Schizophrenia Aggressiveness with the Risk of Suicide based on the Personality and Social Performance Score." Scientia Psychiatrica 2, no. 1 (2021): 38–41. http://dx.doi.org/10.37275/scipsy.v2i1.27.

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A B S T R A C TIntroduction. The risk of schizophrenia for suicide is 10%, of which 10% -15% ofpeople with schizophrenia die of suicide at 20 years of follow-up. Aggressiveness is afactor to be watched out. Other factors are hallucinations, suicide, early-onset,history of schizophrenia, surveillance, age, gender, education, genetics, affect ofdepression. This study aimed to describe the sociodemographic profile,aggressiveness, hallucinations of suicide in schizophrenic patients. Methods. Thedesign of this study is descriptive research. The number of samples in this study was49 schizophrenic pa

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Diveeva, K. A. "Sociological Analysis of the Profile of Extremist." Sociology and Law, no. 3 (October 19, 2021): 40–44. http://dx.doi.org/10.35854/2219-6242-2021-3-40-44.

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The article is devoted to the discussion of the psychological and socio-demographic characteristics of the extremist's personality. The author of the article focuses on the relevance of studying the ideas about the image of an extremist in the public consciousness. The article presents the results of a study conducted in 2021 to identify the attitude of the population of the Krasnoyarsk district to the problems of extremism and radicalism. The results of the study showed that the dominant image of an extremist among the residents of the region is negative. The respondents attributed to the mai

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Deslandes, Manon, Anne Fortin, and Suzanne Landry. "Audit committee characteristics and tax aggressiveness." Managerial Auditing Journal 35, no. 2 (2019): 272–93. http://dx.doi.org/10.1108/maj-12-2018-2109.

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Purpose This study aims to analyze the relationship between a company’s use of aggressive tax planning and several audit committee members’ characteristics, namely, independence, expertise, diligence and gender diversity. Design/methodology/approach This paper is an empirical research using archival data from 289 Canadian listed companies for the 2011-2015 period. Findings The authors find that measures of expertise and diligence are significantly related to tax aggressiveness. Financial expertise and tenure on the audit committee play an important role in constraining tax aggressiveness, as d

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Silva, Rafaela V. N., Lucas A. Berzotti, Marcella G. Laia, et al. "Implications of MTHFD2 expression in renal cell carcinoma aggressiveness." PLOS ONE 19, no. 2 (2024): e0299353. http://dx.doi.org/10.1371/journal.pone.0299353.

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Renal cell carcinoma (RCC) is the most common type of cancer in kidney and is often diagnosed in advanced stages. Until now, there is no reliable biomarker to assess tumor prognosis during histopathological diagnosis. The Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) overexpression has been suggested as prognostic indicator for RCC, however, its protein profile needs to be clarified. This study investigated the MTHFD2 expression in different RCC cohorts, associating it with tumor characteristics and prognostic factors. Gene expression comparisons between non-neoplastic (NN) and tumor samp

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Kocemba-Pilarczyk, Kinga A., Paulina Dudzik, and Katarzyna Leśkiewicz. "The relationship between expression of VIMENTIN and CD146 genes in breast cancer." Bio-Algorithms and Med-Systems 17, no. 1 (2021): 1–7. http://dx.doi.org/10.1515/bams-2020-0058.

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Abstract Objectives CD146 is an adhesive molecule that was originally reported on malignant melanoma cells as a protein crucial for cell adhesion. It is now known that high expression of the CD146 protein is not only characteristic of melanoma, but it occurs on a number of cancers, contributing to worse prognosis and increased aggressiveness. Independent in vitro studies in breast cancer have shown that CD146 protein alone can induce a change in epithelial to mesenchymal transcriptional profile, which is the basis of the tumor aggressiveness and metastasis. Methods In the following work, the c

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Geffroy, Benjamin, Bastien Sadoul, and Agnès Bardonnet. "Behavioural syndrome in juvenile eels and its ecological implications." Behaviour 152, no. 2 (2015): 147–66. http://dx.doi.org/10.1163/1568539x-00003236.

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Behavioural syndrome, which refers to a suite of correlated behaviours across differing situations, has been identified in numerous animals, including fish. The presence and conservation of a behavioural syndrome throughout evolutionary times suggests it confers various advantages at a population level. In eels, such as the European eel (Anguilla anguilla), activity and aggressiveness are important factors in their life history, since both traits influence dispersal and territoriality. In the present study we investigated whether these behavioural traits were consistent at both the nychtemeral

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Espiau-Romera, Pilar, Sarah Courtois, Beatriz Parejo-Alonso, and Patricia Sancho. "Molecular and Metabolic Subtypes Correspondence for Pancreatic Ductal Adenocarcinoma Classification." Journal of Clinical Medicine 9, no. 12 (2020): 4128. http://dx.doi.org/10.3390/jcm9124128.

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Pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, is an extremely lethal disease due to late diagnosis, aggressiveness and lack of effective therapies. Considering its intrinsic heterogeneity, patient stratification models based on transcriptomic and genomic signatures, with partially overlapping subgroups, have been established. Besides molecular alterations, PDAC tumours show a strong desmoplastic response, resulting in profound metabolic reprogramming involving increased glucose and amino acid consumption, as well as lipid scavenging and biosynthesis. Inter

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Calabrese, Giovanna, Anna Dolcimascolo, Filippo Torrisi, Agata Zappalà, Rosario Gulino, and Rosalba Parenti. "MiR-19a Overexpression in FTC-133 Cell Line Induces a More De-Differentiated and Aggressive Phenotype." International Journal of Molecular Sciences 19, no. 12 (2018): 3944. http://dx.doi.org/10.3390/ijms19123944.

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In recent years, microRNAs (miRNAs) have received increasing attention for their important role in tumor initiation and progression. MiRNAs are a class of endogenous small non-coding RNAs that negatively regulate the expression of several oncogenes or tumor suppressor genes. MiR-19a, a component of the oncogenic miR-17-92 cluster, has been reported to be highly expressed only in anaplastic thyroid cancer, the most undifferentiated, aggressive and lethal form of thyroid neoplasia. In this work, we evaluated the putative contribution of miR-19a in de-differentiation and aggressiveness of thyroid

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Sekiguchi, Naohiro, Junko Nomoto, Akihisa Nagata, et al. "Gene Expression Profile Signature of Aggressive Waldenström Macroglobulinemia with Chromosome 6q Deletion." BioMed Research International 2018 (October 4, 2018): 1–8. http://dx.doi.org/10.1155/2018/6728128.

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Background. Waldenström macroglobulinemia (WM) is a rare, indolent B-cell lymphoma. Clinically, chromosome 6q deletion (6q del) including loss of the B lymphocyte-induced maturation protein 1 gene (BLIMP-1) is reported to be associated with poor prognosis. However, it remains unclear how the underlying biological mechanism contributes to the aggressiveness of WM with 6q del. Methods. Here, we conducted oligonucleotide microarray analysis to clarify the differences in gene expression between WM with and without 6q del. Gene ontology (GO) analysis was performed to identify the main pathways unde

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Luna, Herdee Gloriane Cristal, Cher Alaine Cristal Luna, Gloria R. Cristal-Luna, and Cesar Vilela Luna. "Association of dyslipidemia with the aggressive molecular subtypes and pathologic profile of newly diagnosed nonmetastatic breast cancer patients." Journal of Clinical Oncology 30, no. 27_suppl (2012): 19. http://dx.doi.org/10.1200/jco.2012.30.27_suppl.19.

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19 Background: To investigate the association of dyslipidemia with the aggressive pathologic profile and molecular subtypes among the premenopausal and postmenopausal breast cancer patients. Methods: A retrospective review of Filipino breast cancer patients from 1990 to 2010 from an oncology clinic was done. Patients were grouped to pre- and post-menopausal and each group were divided to those with and without dyslipidemia. Association of dyslipidemia with breast cancer aggressiveness, (1) by pathology (histopathologic diagnosis, grade, invasion, TNM stage) and (2) by molecular phenotype (usin

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Adeyinka, Kehinde Oluwatosin, Adeniyi Adenipekun, Atara Ntekim, Augustine Oghenewveyin Takure, and Rotimi Solomon. "Abstract C087: Association of serum lipid profile with prostate cancer risk and aggressiveness in Nigerian men." Cancer Epidemiology, Biomarkers & Prevention 32, no. 12_Supplement (2023): C087. http://dx.doi.org/10.1158/1538-7755.disp23-c087.

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Abstract OBJECTIVE Though prostate cancer (PCa) is the most common cancer and cause of cancer death among Nigerian men, its relationship with serum lipid profiles, a biochemical measurement of dietary fat, has not been explored among Nigerian men. The study aimed to determine the association of serum lipid profile with prostate cancer risk and aggressiveness. METHODS The study was a case-control conducted at University College Hospital, Ibadan, Nigeria. The cases were newly diagnosed prostate cancer patients ages 50-75 years, while the controls were age-matched healthy men with confirmed norma

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Khaliulin, A. V., I. I. Zanin, A. V. Lyamin, I. L. Davydkin, and I. A. Selezneva. "Metabolic profile of blast cells in acute myeloid leukemia. Literature review." Oncohematology 19, no. 4 (2024): 173–81. https://doi.org/10.17650/1818-8346-2024-19-4-173-181.

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The article presents a review of new data on blast cells metabolism and its regulatory mechanisms in acute myeloid leukemia. Particular attention is given to the role of reactive oxygen species in the regulation of signaling pathways and metabolic processes, as well as their influence on the aggressiveness and resistance to chemotherapeutic agents in acute myeloid leukemia. Elevated levels of reactive oxygen species are associated with altered activity of enzymes and proteins involved in cell proliferation and survival. The article also discusses data on the iron role in the formation of malig

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LOSÎI, Elena, and Ana Maria CRÂȘMARU. "PERSONALITY TRAITS OF WOMEN SUBJECTED TO DOMESTIC VIOLENCE." Psihologie, revista ştiinţifico-practică 36 (1-2) (July 13, 2020): 58–65. https://doi.org/10.5281/zenodo.3941613.

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The article describes an important issue for modern society: domestic violence. The victims of domestic aggression are most often considered to be women. The purpose of the research is to study the problem of domestic violence against women and to find the answer to the question; if the personality profile of the women from aggressive backgrounds differs from the personality profile of women from non-aggressive backgrounds. In the finding experiment were included 182 women aged between 22 and 32 from Băcău, Iași, Neamț, Vaslui counties, România.

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Ben Jemaa, Awatef, Yosra Bouraoui, Sataa Sallami, Yassine Nouira, and Ridha Oueslati. "A Comparison of the Biological Features of Prostate Cancer with (PSA+, PSMA+) Profile according to RKIP." BioMed Research International 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/409179.

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Purpose. To investigate differences in the biological features of the most immunoexpressed prostate cancer (PC) profiles (PSA+, PSMA+) according to the RKIP.Methods. 19 PC with dominant Gleason grade ≥8 were studied. Expression of PSA, PSMA, RKIP, Raf-1, MEK-1, ERK-1, ERK-2, p-Akt (T308), p-Akt (S473), NF-κB p50, and NF-κBp65 were detected immunohistochemically.Results. Loss of RKIP in the most immunoexpressed PC (PSA+, PSMA+) profile was associated with increased levels of PSA and PSMA expression. Intensities of immunoreactions to PSA and PSMA were higher in cancer cells negative for RKIP (12

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Lin, Chia-Hung, Chen-Chung Liao, Shu-Ying Wang, et al. "Comparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness." Cancers 14, no. 1 (2022): 243. http://dx.doi.org/10.3390/cancers14010243.

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O-GlcNAcylation is a reversible and dynamic post-translational protein modification catalyzed by O-GlcNAc transferase (OGT). Despite the reported association of O-GlcNAcylation with cancer metastasis, the O-GlcNAc proteome profile for cancer aggressiveness remains largely uncharacterized. Here, we report our comparative O-GlcNAc proteome profiling of two differentially invasive lung adenocarcinoma cell lines, which identified 158 down-regulated and 106 up-regulated candidates in highly invasive cells. Among these differential proteins, a nuclear RNA-binding protein, SAM68 (SRC associated in mi

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Khudina, Yu S., N. V. Tkachenko, and V. G. Zaika. "The relationship between suicidal behavior and personality and affective-behavioral characteristics in patients with organic personality disorder." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 5 (April 28, 2025): 630–39. https://doi.org/10.33920/med-01-2505-08.

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Studies devoted to the topic of suicidal behavior, including in patients with organic personality disorder, are represented mainly by completed suicides. The description of incomplete suicides in this group of subjects is extremely superficial. Given the diversity of mechanisms and factors predisposing suicidal behavior, we decided to analyze this problem and assess the level of aggression, emotional excitability, and impulsivity. A comparative single-step observational study of 94 patients with organic personality disorder was conducted. The participants were divided into subgroups: patients

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Liashenko, Larysa. "The Psychology of Adaptive and Maladaptive Relationships between Parents and Children of Senior School Age." Collection of Research Papers "Problems of Modern Psychology" 63 (April 25, 2024): 129–80. http://dx.doi.org/10.32626/2227-6246.2024-63.159-180.

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The purpose of this article is: to study the concept of “child-parents adaptive relationships”; to describe The Humanistic Conception of child-parents adaptive relations; to present The Psychoanalytic Model of family adaptive education, The Transactional and The Behaviorist Models of Personality Adaptive Education; to describe the results of the experiment with the aim to explain that a person’s implementation of the feature of aggressiveness in destructive maladaptive behavior. Methods of the research. The following theoretical methods of the research were used to solve the tasks formulated i

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Ward, Laura Sterian, Elaine Cristina Morari, Janaina Luisa Leite, et al. "Identifying a risk profile for thyroid cancer." Arquivos Brasileiros de Endocrinologia & Metabologia 51, no. 5 (2007): 713–22. http://dx.doi.org/10.1590/s0004-27302007000500008.

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The large use of simple and effective diagnostic tools has significantly contributed to the increase in diagnosis of thyroid cancer over the past years. However, there is compelling evidence that most micropapillary carcinomas have an indolent behavior and may never evolve into clinical cancers. Therefore, there is an urgent need for new tools able to predict which thyroid cancers will remain silent, and which thyroid cancers will present an aggressive behavior. There are a number of well-established clinical predictors of malignancy and recent studies have suggested that some of the patient’s

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Navin Chandra, Gupta, Arora Shaweta, Kundu Aditi, Sharma Pankaj, Rao Mahesh, and Bhattacharya Ramcharan. "UPLC-Q-TOF-MS-based untargeted studies of the secondary metabolites secreted by Sclerotinia sclerotiorum under the axenic condition." Journal of Plant Science and Phytopathology 6, no. 3 (2022): 173–82. http://dx.doi.org/10.29328/journal.jpsp.1001095.

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The stem rot disease has emerged globally as a major threat to oilseed Brassica's productivity and seed quality. The generalist causal pathogen Sclerotinia sclerotiorum (Lib.) de Bary shows large variability in their aggressiveness and pathogenicity. Revealing the pathogen's metabolic profile and signaling components in host-pathogen interaction is fundamental in understanding host resistance to the disease. In this study, the metabolites released by the pathogenic strains of S. sclerotiorum under the axenic culture have been identified using the untargeted high-resolution UPLC-QTOF-ESI-MS/MS.

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Glas, Annuska M., Marie Jose Kersten, Leonie Delahaye, et al. "Gene Expression Profiles Are Best Suited To Assess Present Though Not Future Clinical Aggressiveness in Follicular Lymphoma." Blood 104, no. 11 (2004): 698. http://dx.doi.org/10.1182/blood.v104.11.698.698.

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Abstract Follicular lymphoma (FL) is characterized by an indolent clinical course and frequent relapses. Transformation to more aggressive disease is common and one of the main causes of death. The time to transformation may vary widely and some patients show early transformation and a poor prognosis. Main questions in FL center on markers to predict transformation (and prognosis) at the time of diagnosis and to accurately assess the transformed phase to tailor the choice of therapy. Currently, prognostic stratification for actual aggressiveness and overall survival is based on histological gr

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Albulescu, Radu, Elena Codrici, Ionela Daniela Popescu, et al. "Cytokine Patterns in Brain Tumour Progression." Mediators of Inflammation 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/979748.

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Inflammation represents the immune system response to external or internal aggressors such as injury or infection in certain tissues. The body’s response to cancer has many parallels with inflammation and repair; the inflammatory cells and cytokines present in tumours are more likely to contribute to tumour growth, progression, and immunosuppression, rather than in building an effective antitumour defence. Using new proteomic technology, we have investigated serum profile of pro- (IL-1β, IL-6, IL-8, IL-12, GM-CSF, and TNF-α) and anti-inflammatory cytokines (IL-4, IL-10), along with angiogenic

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Santos, Driéle B., Geysson J. Fernandez, Luciana M. C. Pardini, Maria Inês M. C. Pardini, and Adriana C. Ferrasi. "Transcriptomic Profile of Canine Mammary Ductal Carcinoma." International Journal of Molecular Sciences 24, no. 6 (2023): 5212. http://dx.doi.org/10.3390/ijms24065212.

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Dogs can be excellent models for spontaneous studies about breast cancers, presenting similarities in clinical behavior and molecular pathways of the disease. Thus, analyses of the canine transcriptome can identify deregulated genes and pathways, contributing to the identification of biomarkers and new therapeutic targets, benefiting humans and animals. In this context, this study aimed to determine the transcriptional profile of canine mammary ductal carcinoma and contribute to the clarification of the importance of deregulated molecules in the molecular pathways involved in the disease. Ther

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Ouldamer, Lobna, Marie-Lise Jourdan, Michelle Pinault, Flavie Arbion, and Caroline Goupille. "Accumulation of Arachidonic Acid, Precursor of Pro-Inflammatory Eicosanoids, in Adipose Tissue of Obese Women: Association with Breast Cancer Aggressiveness Indicators." Biomedicines 10, no. 5 (2022): 995. http://dx.doi.org/10.3390/biomedicines10050995.

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While obesity is linked to cancer risk, no studies have explored the consequences of body mass index (BMI) on fatty acid profiles in breast adipose tissue and on breast tumor aggressiveness indicators. Because of this, 261 breast adipose tissue samples of women with invasive breast carcinoma were analyzed. Fatty acid profile was established by gas chromatography. For normal-weight women, major changes in fatty acid profile occurs after menopause, with the enrichment of long-chain polyunsaturated fatty acids (LC-PUFAs) of both n-6 and n-3 series enrichment, but a stable LC-PUFAs n-6/n-3 ratio a

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Ouldamer, Lobna, Marie-Lise Jourdan, Michelle Pinault, Flavie Arbion, and Caroline Goupille. "Accumulation of Arachidonic Acid, Precursor of Pro-Inflammatory Eicosanoids, in Adipose Tissue of Obese Women: Association with Breast Cancer Aggressiveness Indicators." Biomedicines 10, no. 5 (2022): 995. http://dx.doi.org/10.3390/biomedicines10050995.

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While obesity is linked to cancer risk, no studies have explored the consequences of body mass index (BMI) on fatty acid profiles in breast adipose tissue and on breast tumor aggressiveness indicators. Because of this, 261 breast adipose tissue samples of women with invasive breast carcinoma were analyzed. Fatty acid profile was established by gas chromatography. For normal-weight women, major changes in fatty acid profile occurs after menopause, with the enrichment of long-chain polyunsaturated fatty acids (LC-PUFAs) of both n-6 and n-3 series enrichment, but a stable LC-PUFAs n-6/n-3 ratio a

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Yamasaki, Tomohiro, Adrian Lita, Tyrone Dowdy, Mark Gilbert, and Mioara Larion. "CBMT-07. BIOMARKERS OF AGGRESSIVENESS IN IDH MUTANT GLIOMA." Neuro-Oncology 21, Supplement_6 (2019): vi34. http://dx.doi.org/10.1093/neuonc/noz175.129.

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Abstract BACKGROUND Gliomas with isocitrate dehydrogenase (IDH) mutations in adults evolve from lower-grade gliomas to secondary glioblastomas (GBM), a fatal disease with fast progression. IDH mutation occurs early in tumorigenesis, and persistently contribute to the reprograming of glucose, lipid and amino acid metabolism. This offer a plethora of potential biomarkers of progression. However, because it is extremely difficult to detect the distribution and transfer of metabolites changing in every moment in a single cell, the involvement of metabolites produced by mutant IDH in malignant prog

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Souza, Danival José de, Terezinha Maria Castro Della Lucia, and Luiz Cláudio de Almeida Barbosa. "Discrimination between workers of Acromyrmex subterraneus molestans from monogynous and polygynous colonies." Brazilian Archives of Biology and Technology 49, no. 2 (2006): 277–85. http://dx.doi.org/10.1590/s1516-89132006000300013.

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Behavioral assays were conducted with individuals from monogynous and polygynous colonies of Acromyrmex subterraneus molestans to evaluate the discriminatory ability of ant workers. These bioassays showed that this subspecies could not discriminate among non-nestmates or nestmate workers. However, nestmates of these same colonies did discriminate among workers of another subspecies Ac. subterraneus subterraneus. When discrimation occurred there were no differences in the response of workers from either monogynous or polygynous colonies. Similarities or differences in the chemical profile of bo

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Zanon, Maicon Fernando, Cristovam Scapulatempo-Neto, Ricardo Ribeiro Gama, Márcia Maria Chiquitelli Marques, Rui Manuel Reis, and Adriane Feijó Evangelista. "Identification of MicroRNA Expression Profiles Related to the Aggressiveness of Salivary Gland Adenoid Cystic Carcinomas." Genes 14, no. 6 (2023): 1220. http://dx.doi.org/10.3390/genes14061220.

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Adenoid cystic carcinoma (ACC) has been reported as the second most frequent carcinoma of the salivary glands. Few studies have associated the miRNAs expression with ACC aggressiveness. In this study, we evaluated the miRNAs profile of formalin-fixed, paraffin-embedded (FFPE) samples of salivary gland ACC patients using the NanoString platform. We studied the miRNA expression levels associated with the solid growth pattern, the more aggressive histologic feature of ACCs, compared with the tubular and cribriform growth patterns. Moreover, the perineural invasion status, a common clinicopatholog

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Lin, Xiaoqi, Sydney D. Finkelstein, Bing Zhu, and Jan F. Silverman. "Molecular analysis of multifocal papillary thyroid carcinoma." Journal of Molecular Endocrinology 41, no. 4 (2008): 195–203. http://dx.doi.org/10.1677/jme-08-0063.

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Papillary thyroid carcinoma (PTC) frequently presents as a multifocal process. To study the importance of separating independent primary (IP) from intrathyroid metastatic (ITM) PTC, we examined 19 molecular markers on 42 separate tumors from 18 multifocal PTC cases. In 12 of 18 (66.7%) cases, including 6 of 12 (50%) papillary microcarcinoma cases, the same or similar profile of loss of heterozygosities (LOH) and v-raf murine sarcoma viral oncogene homolog B1 (BRAF) mutation was demonstrated, indicating that they were from the same primary and represented ITM. Different profiles of LOHs and BRA

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Dairkee, Shanaz H., Junhee Seok, Stacey Champion, et al. "Bisphenol A Induces a Profile of Tumor Aggressiveness in High-Risk Cells from Breast Cancer Patients." Cancer Research 68, no. 7 (2008): 2076–80. http://dx.doi.org/10.1158/0008-5472.can-07-6526.

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Neri, Ludovico, Beatrice Marziani, Pierluigi Sebastiani, et al. "Aggressiveness in Italian Children with ADHD: MAOA Gene Polymorphism Involvement." Diseases 12, no. 4 (2024): 70. http://dx.doi.org/10.3390/diseases12040070.

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ADHD is a neurodevelopmental disorder that children and adults can develop. A complex interplay of genetic and environmental factors may underlie interindividual variability in ADHD and potentially related aggressive behavior. Using high-resolution molecular biology techniques, we investigated the impact of some MAOA and SLC6A4 variations on ADHD and aggressive behavior in a group of 80 Italian children with ADHD and in 80 healthy controls. We found that homozygous genotypes of MAOA rs6323 and rs1137070 were associated with an increased risk of ADHD (p = 0.02 and p = 0.03, respectively), where

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Bozzini, Nicolò, Sofia Avnet, Nicola Baldini, and Margherita Cortini. "Epigenetic Regulation Mediated by Sphingolipids in Cancer." International Journal of Molecular Sciences 24, no. 6 (2023): 5294. http://dx.doi.org/10.3390/ijms24065294.

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Epigenetic changes are heritable modifications that do not directly affect the DNA sequence. In cancer cells, the maintenance of a stable epigenetic profile can be crucial to support survival and proliferation, and said profile can differ significantly from that of healthy cells. The epigenetic profile of a cancer cell can be modulated by several factors, including metabolites. Recently, sphingolipids have emerged as novel modulators of epigenetic changes. Ceramide and sphingosine 1-phosphate have become well known in cancer due to activating anti-tumour and pro-tumour signalling pathways, res

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Tselentis, Dimitrios I., and Eleonora Papadimitriou. "Driver Profile and Driving Pattern Recognition for Road Safety Assessment: Main Challenges and Future Directions." IEEE Open Journal of Intelligent Transportation Systems 4 (January 17, 2023): 83–100. https://doi.org/10.1109/OJITS.2023.3237177.

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This study reviews the Artificial Intelligence and Machine Learning approaches developed thus far for driver profile and driving pattern recognition, representing a set of macroscopic and microscopic behaviors respectively, to enhance the understanding of human factors in road safety, and therefore reduce the number of crashes. It provides a definition of the two scientific fields in terms of safety, and identifies the most efficient approaches used regarding methodology, data collection and driving metrics. Results show that K-means and Neural Networks are the most commonly used methodologies

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Kariche, Nora, Nabila Moulaï, Leila-Sarah Sellam, et al. "Expression Analysis of the Mediators of Epithelial to Mesenchymal Transition and Early Risk Assessment of Therapeutic Failure in Laryngeal Carcinoma." Journal of Oncology 2019 (December 6, 2019): 1–15. http://dx.doi.org/10.1155/2019/5649846.

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Laryngeal squamous cell carcinoma (LSCC) is an aggressive malignancy which lacks early predictors of prognosis. Here, we hypothesized that expression and prognostic characterization of the critical mediators of epithelial to mesenchymal transition (EMT) may provide key information in this regard. Linear regression and multiple correspondence analyses were performed on immunohistochemical data obtained from 20 invasive tumors. Principal component and unsupervised hierarchical clustering were used to analyze the dataset patterns associating with LSCC metastatic profile. Survival and death risk a

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You, Daeun, Hyungjoo Kim, Yisun Jeong, et al. "Tumorigenicity of EGFR- and/or HER2-Positive Breast Cancers Is Mediated by Recruitment of Tumor-Associated Macrophages." International Journal of Molecular Sciences 24, no. 2 (2023): 1443. http://dx.doi.org/10.3390/ijms24021443.

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Basal-like breast cancer (BLBC) has a clinically aggressive nature. It is prevalent in young women and is known to often relapse rapidly. To date, the molecular mechanisms regarding the aggressiveness of BLBC have not been fully understood. In the present study, mechanisms of aggressiveness of BLBC involving EGFR and/or HER2 expression and interactions between tumor and tumor-associated macrophages (TAMs) were explored. The prognosis of breast cancer patients who underwent surgery at Samsung Medical Center was analyzed. It was found that the co-expression of EGFR and HER2 was associated with a

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Okręglicka, Małgorzata. "ORGANIZATIONAL CULTURE SHAPED BY ENTREPRENEURIAL ORIENTATION IN FAMILY FIRMS." Zeszyty Naukowe Wyższej Szkoły Humanitas Zarządzanie 22, no. 2 (2021): 9–21. http://dx.doi.org/10.5604/01.3001.0015.0033.

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Contemporary enterprises are still looking for ways and methods of achieving a competitive advantage, which invariably include entrepreneurship. Entrepreneurial orientation is an organizational construct consisting of five dimensions: proactivity, innovation, competitive aggressiveness, autonomy and risk taking. Family businesses show a significant specificity of functioning in many areas due to the dominant influence of the family on the management of such entities. It is not a uniform group, and individual companies may significantly differ, e.g. depending on the profile of their activity. H

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Ortas, Eduardo, and Isabel Gallego-Álvarez. "Bridging the gap between corporate social responsibility performance and tax aggressiveness." Accounting, Auditing & Accountability Journal 33, no. 4 (2020): 825–55. http://dx.doi.org/10.1108/aaaj-03-2017-2896.

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PurposeThis paper addresses the role of corporate social responsibility (CSR) performance as a potential mechanism for reducing firms' likelihood of engaging in tax aggressiveness (TAG). The paper also contributes to the existing literature by addressing the moderating effect of national cultures on the link between CSR performance and corporate TAG.Design/methodology/approachThe focus is placed on an unbalanced panel of 2,696 companies distributed in 30 countries and seven economic sectors over the period of 2002–2014.FindingsThe results provide support for those companies achieving high corp

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PALAGHIA, Carmen. "THE DYNAMIC OF THE AGGRESSOR-VICTIM RELATIONSHIP SPECIFIC TO THE SCHOOL BULLYING AND CYBERBULLYING PHENOMENON." Social Research Reports 11, no. 2 (2019): 37–48. http://dx.doi.org/10.33788/srr11.2.3.

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This study conceptually and etiologically defines the harassment among students, either face to face or virtually, the types of bullying and cyberbullying from the perspective of the dynamic of the aggressor-victim relationship. In this regard, the aggressor and the victim’s profile are outlined, as well as the fluctuations of the attitudinal-behavioral pattern within the victim-aggressor-school triad. By referring to the aggressiveness among students, we will predominantly analyse the school harassment, emphasizing both the determinant factors and the effects on the psychological plan with re

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Robert, P. H., and H. Allain. "Clinical management of agitation in the elderly with tiapride." European Psychiatry 16, S1 (2001): 42s—47S. http://dx.doi.org/10.1016/s0924-9338(00)00527-7.

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SummaryAgitated behaviors such as uncooperativeness with necessary care, motor hyperactivity, and verbal or physical aggression are some of the most commonly reported complications in dementia and organic disorders in elderly subjects. These symptoms present greater clinical challenges and management issues than the cognitive deficits. Antipsychotics are the most commonly used psychotropic agents for treating these types of symptoms.The aims of this article are to review clinical studies with tiapride, a substituted benzamide, and more specifically to present recent data coming from two double

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Velame, Karinna V. C., Anelita de Jesus Rocha, Mileide dos Santos Ferreira, et al. "Evidence of Correlation between Pathogenicity, Avirulence Genes, and Aggressiveness of Fusarium oxysporum f. sp. cubense in Banana “Cavendish” and “Prata” Subgroups." Horticulturae 10, no. 3 (2024): 228. http://dx.doi.org/10.3390/horticulturae10030228.

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Fusarium wilt caused by Fusarium oxysporum f. sp. cubense (Foc) is one of the most destructive diseases in banana farming worldwide. Knowledge of the factors of genetic diversity and virulence of the pathogen contributes to the development of resistant cultivars and management strategies based on exclusion. In this study, phenotypic traits such as virulence and aggressiveness in a sample of 52 Foc isolates were analyzed and their relationship to the presence of putative effectors of gene SIX (Secreted in Xylem) pathogenicity homologs was verified. The similarity matrix revealed three isolates

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Lupco, Kevereski, Kotevska Dimovska Marija та Ristevski Dragan. "ТHE INFLUENCE OF THE EMOTIONAL INTELIGENCE IN PROTECTION OF THE MENTAL HEALTH IN CONDITIONS OF A PSYCHOSOCIAL STRESS". International Journal of Cognitive Research in Science, Engineering and Education (IJCRSEE) 4, № 1 (2016): 17–22. https://doi.org/10.5937/IJCRSEE1601017K.

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If our time is stressful, than protecting and promoting of our mental health is imperative of the time that is coming.In modern literature there is a huge interest for the determination of the mental health of the emotional intelligence, which is treated as a factor for it’s keeping and development. This paper is based on the assumption that the emotional intelligence has considerable contribution for understanding the relationship between psychosocial stress and mental health, seen through three important variables: self-confidence, depression and aggressiveness. In the research were in

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