Dissertations / Theses on the topic 'Aggregation Platform'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 20 dissertations / theses for your research on the topic 'Aggregation Platform.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Ström, Erik. "Podcast aggregation system : with cross platform synchronization." Thesis, Mittuniversitetet, Avdelningen för data- och systemvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-33281.
Full textYan, Jing. "Analysis of amyloid aggregation on water-based microfluidics platform." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708312.
Full textSaunders, Janet Catherine. "An in vivo platform for identifying protein aggregation inhibitors." Thesis, University of Leeds, 2014. http://etheses.whiterose.ac.uk/7622/.
Full textOlurin, Olumuyiwa. "Policy Merger System for P3P in a Cloud Aggregation Platform." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/23624.
Full textJanoška, Daniel. "Moderní technologie v OLAP." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2008. http://www.nusl.cz/ntk/nusl-235902.
Full textSchwedhelm, Ivo Peter [Verfasser], Jan [Gutachter] Hansmann, Philipp [Gutachter] Wiedemann, and Heike [Gutachter] Walles. "A non-invasive microscopy platform for the online monitoring of hiPSC aggregation in suspension cultures in small-scale stirred tank bioreactors / Ivo Peter Schwedhelm ; Gutachter: Jan Hansmann, Philipp Wiedemann, Heike Walles." Würzburg : Universität Würzburg, 2019. http://d-nb.info/1202013600/34.
Full textIvanou, Aliaksandr. "A Centralised data aggregation layer across different consuming platforms." Thesis, Uppsala universitet, Institutionen för informationsteknologi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-263260.
Full textDomingos, João Nuno Silva Tabar. "On the cloud deployment of a session abstraction for service/data aggregation." Master's thesis, Faculdade de Ciências e Tecnologia, 2013. http://hdl.handle.net/10362/9923.
Full textThe global cyber-infrastructure comprehends a growing number of resources, spanning over several abstraction layers. These resources, which can include wireless sensor devices or mobile networks, share common requirements such as richer inter-connection capabilities and increasing data consumption demands. Additionally, the service model is now widely spread, supporting the development and execution of distributed applications. In this context, new challenges are emerging around the “big data” topic. These challenges include service access optimizations, such as data-access context sharing, more efficient data filtering/ aggregation mechanisms, and adaptable service access models that can respond to context changes. The service access characteristics can be aggregated to capture specific interaction models. Moreover, ubiquitous service access is a growing requirement, particularly regarding mobile clients such as tablets and smartphones. The Session concept aggregates the service access characteristics, creating specific interaction models, which can then be re-used in similar contexts. Existing Session abstraction implementations also allow dynamic reconfigurations of these interaction models, so that the model can adapt to context changes, based on service, client or underlying communication medium variables. Cloud computing on the other hand, provides ubiquitous access, along with large data persistence and processing services. This thesis proposes a Session abstraction implementation, deployed on a Cloud platform, in the form of a middleware. This middleware captures rich/dynamic interaction models between users with similar interests, and provides a generic mechanism for interacting with datasources based on multiple protocols. Such an abstraction contextualizes service/users interactions, can be reused by other users in similar contexts. This Session implementation also permits data persistence by saving all data in transit in a Cloud-based repository, The aforementioned middleware delivers richer datasource-access interaction models, dynamic reconfigurations, and allows the integration of heterogenous datasources. The solution also provides ubiquitous access, allowing client connections from standard Web browsers or Android based mobile devices.
Du, Qianzhou. "Extracting the Wisdom of Crowds From Crowdsourcing Platforms." Diss., Virginia Tech, 2019. http://hdl.handle.net/10919/102032.
Full textDoctor of Philosophy
Andersson, Oskar. "Design of a system for visualizing trends and behaviors based on customer data." Thesis, Linköpings universitet, Interaktiva och kognitiva system, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-175633.
Full textLam, Lawrence G. "Digital Health-Data platforms : biometric data aggregation and their potential impact to centralize Digital Health-Data." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/106235.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (page 81).
Digital Health-Data is being collected at unprecedented rates today as biometric micro sensors continue to diffuse into our lives in the form of smart devices, wearables, and even clothing. From this data, we hope to learn more about preventative health so that we can spend less money on the doctor. To help users aggregate this perpetual growth of biometric "big" data, Apple HealthKit, Google Fit, and Samsung SAMI were each created with the hope of becoming the dominant design platform for Digital Health-Data. The research for this paper consists of citings from technology strategy literature and relevant journalism articles regarding recent and past developments that pertain to the wearables market and the digitization movement of electronic health records (EHR) and protected health information (PHI) along with their rules and regulations. The culmination of these citations will contribute to my hypothesis where the analysis will attempt to support my recommendations for Apple, Google, and Samsung. The ending chapters will encompass discussions around network effects and costs associated with multi-homing user data across multiple platforms and finally ending with my conclusion based on my hypothesis.
by Lawrence G. Lam.
S.M. in Engineering and Management
Shahid, Shantana. "Setting Up Shop in the Digital Bazaar – Bangladeshi Blue-Collar Service-Providers’ Adoption of a Business Aggregator." Thesis, Malmö universitet, Fakulteten för kultur och samhälle (KS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-22501.
Full textMacoun, Jakub. "Integrace statistické aplikace a herního systému s využitím datového skladu a platformy Java." Master's thesis, Vysoká škola ekonomická v Praze, 2013. http://www.nusl.cz/ntk/nusl-192020.
Full textGranath, Isabelle, and Kristin Holmlund. "Business Model Design for Digital Energy Trading Platforms : An Exploratory Study of Local Energy Market Designs." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-279616.
Full textDen traditionella elmarknaden, karaktäriserad av en centraliserad styrning, är inte längre hållbar då utvecklingen av marknaden går mot ett allt mer elektrifierat, decentraliserat och digitaliserat samhälle. Ökande energipriser, växande oro för klimatfrågor tillsammans med en allt snävare reglering av energimarknaden har resulterat i en omfattande ökning av förnybara energikällor. Denna utveckling förväntas förändra sektorns struktur, där en lämplig marknadsdesign som kan hantera detta återstår att identifiera. Syftet med denna studie var att undersöka hur en affärsmodell för en digital plattform, anpassad för att hantera lokal energidelning, kan utformas. Denna studie bidrar till en ny dimension av energitransformationen från ett multi-nivå-perspektiv genom att studera ett särskilt område av övergången i form av flexibla marknadsplattformar. Det ökande behovet av flexibla lösningar, där konsumenter blir prosumenter och energi delas lokalt via digitala plattform innebär osäkerheter och utmaningar. En lämplig affärsmodell som kan anknyta de nya tekniska lösningarna som krävs till lokala energimarknader bör därav definieras. Trots att forskningsområdet som berör lokala energimarknader kan anses relativt nytt och delvis outforskat, har målet att undersöka affärsmodellkoncept för en lokal energimarknadsplattform uppnåtts genom en fallstudie och iterationer av teorier inom flertalet områden. Denna studie bidrar med en analytisk undersökning av fem innovativa projekt som alla utvecklar digitala plattformar för att möjliggöra integrering av flexibilitet till elmarknaden. Detta bidrar även till det kunskapsgap som har identifierats mellan design och implementering fas vid utvecklandet av lokala energimarknader, genom föreslagna parameter som anses grundläggande och som bör tas hänsyn till. Baserat på resultatet presenterades ett förslag på en lämplig design för affärsmodell samt en tillhörande marknadsdesign. Huvudsyftet med den föreslagna marknadsdesignen är att utgöra en grund för gynnandet av en mer flexibel elektricitet hantering. Detta möjliggörs genom introduktionen av prosumenter till marknaden, där allt mer elektricitet produceras från förnybara källor och där konsumtion samt produktion regleras med hjälp av integrerade lagringsenheter. Målet är att upprätthålla ett balanserat och transparent distributionsnät till lägsta möjliga kostnad, medan marknaden även fungerar som ett reservlager mot kraftnätet, vilket minskar risken för kapacitetsbrist runt om i Sverige. Ytterligare insikter från denna studie påvisar hur de befintliga energitillgångarna kan utnyttjas på ett mer flexibelt och effektivt sätt, vilka stöds av de nyligen presenterade rekommendationerna från EU:s Clean Energy-paket.
PAN, YAN-SYUN, and 潘彥勛. "Web Information Aggregation and Social Platform for IT Applications." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/277d2f.
Full text國立暨南國際大學
資訊工程學系
105
Modern people are familiar to use search engines to solve their daily problems. Google provides well search services; however, search results are optimized for general purpose not for user’s requirements about specific domain problems. Also, Google search results present relevant web links, users frequently spend long time to navigate possible links for seeking adequate information. Such problems also happen in the IT domain. People having IT troubles always wait for IT staffs to solve problems. When IT staffs cannot solve hard problems, they are hard to find solutions from Web search engines on time. To improve IT services, we develop the itQA social platform that integrates social services for general users and IT staffs. Based on the platform, IT questions are aggregated into the same pool. Also, itQA integrates Web Crawler and Search Engine techniques that aggregate IT information into the platform by crawling and indexing QA contents from popular IT websites. In this way, all IT QA contents can be aggregated into the same platform so that accumulated user logs and feedbacks can be analyzed to gradually improve the quality of the itQA platform.
Calafate, Sara de Sa Cesariny. "Tauopathy seeding models as a platform for Tau aggregation and clearance study." Master's thesis, 2012. http://hdl.handle.net/10316/25016.
Full textA doença de Alzheimer é a forma de demência mais prevalente. Quando a proteína Tau perde a conformação correcta forma agregados, começando por originar oligomeros e mais tarde fibrilas de grandes dimensões dando origem a trancas neurofibrilares. Alguns estudos sugerem que estas espécies são transmitidas através das áreas do cérebro danificando o circuito neuronal. Para parar o avanço da doença muitos trabalhos têm em foco o desenvolvimento de terapias que manipulam a fosforilação desta proteína, a estabilização dos microtubulos e a indução da degradação da Tau. Para desenvolver terapias que impedem a agregação ou que induzam a degradação da Tau, é necessário desenvolver modelos que recapitulam a agregação. Neste trabalho “seeding effect” foi a estratégia utilizada para induzir a agregação da hTauP301L. No presente trabalho dois modelos in vitro baseados nesta estratégia foram utilizados – um desenvolvido em linhas celulares e outro em culturas neuronais primarias – onde se observou a hiper-fosforilação e agregação da Tau. A co-expressão da GSK3β aumentou a fosforilacao na ser202/thr205 na Tau solúvel e insolúvel, mas apenas a sua expressão não foi suficiente para induzir agregação. Em culturas neuronais primárias a fosforilação e agregação da Tau aumentam ao longo do tempo. A inibição da Hsp90 reduziu os níveis de Tau totais de e fosforilados no epitopo AT8, dando importância a esta estratégia como um potencial mecanismo para degradação da Tau.Com este trabalho produzimos dois modelos onde estudos em nucleação, agregação e transmissão sináptica da Tau poderão ser feitos. Estes modelos são ferramentas válidas para o desenvolvimento de fármacos para AD e outras Tauopatias
Alzheimer Disease is the most prevalent dementia. Abnormal folding of Tau leads to generation of aggregated Tau species like oligomers and further NFTs. Toxic Tau species were suggested to spread trough human brain and damage the neuronal circuit. To halt disease progression a noteworthy development in therapies based on phosphorylation modulation, Microtubule stabilization and enchantment of Tau clearance have been done. To develop therapies against Tau aggregation and aggregates clearance, the build up of models that recapitulates Tau pathology are required. In the following work the “seeding” strategy was used to achieve aggregation of hTauP301L. We worked with two in-vitro seeding models – cellular and primary neuronal- where phosphorylated insoluble hTauP301L is present. GSK3β was shown to increase ser202/thr205 phosphorylation in soluble and insoluble hTauP301L expressed in QBI but was not sufficient to induce aggregation alone. In primary neuronal seeding model tau aggregation and phosphorylation was increased over-time. Hsp90 inhibition was found to reduce total and AT8 immuno-reactive hTauP301L levels, emerging as a potential drug for Tau clearance. With this work we provide two models to study the mechanisms behind tau nucleation, aggregation, and trans-synaptic spreading. These models are valuable tools for the development of drugs for AD and Tauopathies.
Lu, Yea-Ting, and 呂雅婷. "Establishment of Neurotoxin-Induced and α-Synuclein Aggregation Parkinson’s Disease Cell Models as Drug Testing Platform." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/ntg8q2.
Full text國立臺灣師範大學
生命科學研究所
102
Parkinson’s disease (PD) is the second most common neurodegenerative disorder affecting people in their middle and old age. It is characterized by resting tremor, rigidity, akinesia and postural instability and associated with selected loss of dopaminergic (DA) neuron in the substantianigra pars compacta. Combinations of environmental and genetic factors are thought to cause PD. Among the genetic factors contributing to the pathogenesis of PD, mutations in the α-synuclein gene such as A30P, A53T and E46K increased aggregate formation and mutations in Parkin, DJ-1 and PINK1 impaired mitochondrial function. In addition, environmental factors as well as aging are also thought to contribute the development of the disease. No effective treatment for the disease currently urges the development of new agents that may halt the degeneration of PD. In this study, human neuroblastoma SH-SY5Y cells were differentiated toward the DA phenotype in the presence of retinoic acid (RA) follow by 12-O-tetradecanoyl-phorbol-13-acetate (TPA). Greatly up-regulated tyrosine hydroxylase (TH, DA neuronal marker) in SH-SY5Y cells was observed following 7 days of differentiation. These TH-positive cells exhibited a mature morphology with long, branched cell processes and large cell bodies. Addition of MPP+ (1-methyl-4-phenylpyridinium), a potent complex I inhibitor in DA neurons, to the above SH-SY5Y cells caused significant cell death compared with untreated cells. This MPP+-induced cell death was used to screen herbal extracts provided by Industrial Technology Research Institute (ITRI). Cell viability assay indicated that pretreatment of herbal extracts NTNU-043, -057, -059, -125, -293, -313, -331, -385, -450, and -514 protected undifferentiated SH-SY5Y cells against MPP+-induced toxicity, whereas pretreatment of herbal extracts NTNU-092 and -313 protected differentiated SH-SY5Y cells against MPP+-induced toxicity.
Schwedhelm, Ivo Peter. "A non-invasive microscopy platform for the online monitoring of hiPSC aggregation in suspension cultures in small-scale stirred tank bioreactors." Doctoral thesis, 2019. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-192989.
Full textDie Vermehrung von humanen induzierten pluripotenten Stammzellen (hiPSCs) im Indus- triemaßstab wird durch skalierbare Bioprozesse in aktiv durchmischten Rührkessel-Bioreaktoren (CSTRs) ermöglicht. Hierbei zeichnet sich das Wachstum von hiPSCs durch die charakteristische Bildung von sphäroidischen Zellaggregaten aus, deren Durchmesser sich im Laufe der Kultivierung vergrößert. Die Agglomeration von hiPSCs ist sowohl abhängig vom Grad der Durchmischung als auch vom jeweiligen Kulturgefäß, und stellt somit einen wichtigen Prozessparameter dar, welcher während der Prozessskalierung berücksichtigt werden muss. Weiterhin weisen hiPSCs in Aggregaten, welche eine kritische Größe überschreiten, eine erhöhte Wahrscheinlichkeit auf, ihre Pluripotenz zu verlieren oder hinsichtlich ihrer Viabilität beeinträchtigt zu werden. Auf Grundlage dessen wurde im Rahmen dieser Arbeit eine Plattform für die Durchführung von hiPSCs-Suspensionskulturen en- twickelt, welche die zerstörungsfreie Überwachung des hiPSC-Aggregatwachstums in Echtzeit durch den Einsatz von in situ-Mikroskopie ermöglicht. Neben den eigens entworfenen Bioreaktoren, welche zum Großteil aus 3D-gedruckten Komponenten bestehen, wurde eine Peripherie in Form eines Inkubator-Prototyps entwickelt und konstruiert, welcher die Unterbringung der Bioreaktoren, der Systemkomponenten zur Erzeugung von Zellkulturbedingungen sowie einer in situ-Mikroskop- Spezialanfertigung gewährleistet. Als Ausgangspunkt der Entwicklung des CSTR Systems diente ein Strömungssimulationsmodell, welches dazu verwendet wurde, prozesstechnische Kennzahlen zu er- mitteln um das CSTR System hinsichtlich des spezifischen Leistungseintrags, der Mischzeit und der Scherbelastung zu charakterisieren. Das erstellte Simulationsmodell wurde zudem erfolgreich an- hand eines Messdatenabgleichs der Mischzeit hinsichtlich seiner Aussagekraft validiert. Des Weit- eren wurde die Funktionsfähigkeit des gesamten Systems durch Langzeitversuche belegt. Hierbei wurden hiPSCs in den entwickelten Bioreaktoren über einen Zeitraum von vier Passagen expandiert und das Aggregatwachstum mittels in situ-Mikroskopie in Kombination mit einer automatisierten Bildauswertung beschrieben. Überdies hinaus wurde die Qualität der kultivierten hiPSCs hinsichtlich ihrer Differenzierungskapazität durch den Nachweis von Pluripotenzmarkern auf RNA (qRT-PCR und PluriTest) sowie Proteinebene (Durchflusszytometrie) untersucht
Hannich, Theresa. "Digital transformation in the german sports broadcasting industry : a qualitative study on the impact of the disruptor OTT." Master's thesis, 2020. http://hdl.handle.net/10400.14/31131.
Full textO estudo investiga o impacto da tecnologia OTT (over-the-top) para a indústria alemã de transmissão desportiva. Para este efeito do estudo, a OTT é definida como uma tecnologia de streaming que ultrapassa a distribuição tradicional e oferece conteúdos diretamente através da Internet, em qualquer lugar e a qualquer momento. A tecnologia já existente de televisão tradicional é desafiada por modelos de negócio inovadores que fornecem conteúdos desportivos através da Internet. Os canais OTT puros como o DAZN e gigantes digitais como a Amazon entraram no mercado dos direitos desportivos, obrigando os antigos líderes a repensar o seu modelo de negócio. Além da modificação das exigências dos consumidores, diferentes dinâmicas de mercado, como a digitalização dos direitos desportivos, a tendência para D2C (direct-to-consumer), a segmentação de nichos de mercado e as características em torno das experiências digitais dos adeptos, impulsionam a OTT a tornar-se a tecnologia de consumo desportivo líder. No entanto, as conclusões dos resultados qualitativos e quantitativos identificaram a consolidação do mercado para um número concentrado de agregadores de conteúdos que operam no segmento dos direitos desportivos premium como o cenário mais provável para a indústria dentro de 5-10 anos. Esta tendência vai de par com um jogo final de conteúdos iniciado pelos titulares de direitos de topo que implementam modelos de negócio D2C para os mercados secundários. A grande mudança no mercado será o fim da fragmentação do mercado para um mercado de direitos desportivos mais consolidado, liderado pelas principais plataformas D2C e OTT.
Rouiller, André Santos. "Plataforma de agregação e análise de informação institucional e nas redes sociais: uma aplicação às camadas jovens de futebol." Master's thesis, 2020. http://hdl.handle.net/10071/21532.
Full textWe are currently witnessing an expansion of football in Portugal, with several key players thriving in the best European clubs and being transferred by massive compensations. Some of the existing sports press, both in paper and electronic format, are not open to increase football knowledge among the youth players because they do not have a great visibility with the public, as does senior football and nowadays, even women's football. With the identification of this problem among youth teams and the analysis made on several websites, both institutional and journalistic/informative, the need to aggregate dispersed information about youth football players in Portugal was detected. Taking into account that social networks are very present in our daily lives with football clubs, players and supporters using them frequently, the information contained proved to be essential for the performance of the players. In this context, a platform has been developed which will provide more content and information regarding youth football players, through an approach that allows the use of the platform in different devices of different sizes. With the tests carried out on the platform, it was observed that the aggregation of the information obtained is useful and applicable to youth football players, guaranteeing almost instant access to data taken from various sources, which contributes to the improvement of football and its clubs in Portugal, more specifically, amateur clubs that do not have the financial resources to invest in advanced technology for the sourcing of information and statistical analysis.