Relevant bibliographies by topics / Ageing-related

Academic literature on the topic 'Ageing-related'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Ageing-related"

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Minton, Kirsty. "Inflammasome-related ageing." Nature Reviews Immunology 17, no. 2 (January 23, 2017): 77. http://dx.doi.org/10.1038/nri.2017.3.

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Safarova, G., L. Kozlov, O. Mikhailova, and A. Safarova. "POPULATION AGEING AND AGEING-RELATED POLICIES IN RUSSIA." Innovation in Aging 1, suppl_1 (June 30, 2017): 1090. http://dx.doi.org/10.1093/geroni/igx004.3998.

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Jung, Hwa Jin, and Yousin Suh. "Circulating miRNAs in Ageing and Ageing-Related Diseases." Journal of Genetics and Genomics 41, no. 9 (September 2014): 465–72. http://dx.doi.org/10.1016/j.jgg.2014.07.003.

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Kuro-o, Makoto. "Ageing-related receptors resolved." Nature 553, no. 7689 (January 2018): 409–10. http://dx.doi.org/10.1038/d41586-017-09032-4.

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Muñoz, Gtaciela E., and C. P. Sotomayor. "Ageing-related changes inMycoplasma canadensemembranes." Journal of Applied Bacteriology 72, no. 1 (January 1992): 51–56. http://dx.doi.org/10.1111/j.1365-2672.1992.tb04881.x.

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Fu, Zhiling, Jin Zhang, and Yan Zhang. "Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases." Oxidative Medicine and Cellular Longevity 2022 (March 18, 2022): 1–17. http://dx.doi.org/10.1155/2022/2249749.

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Ageing is a physiological process of progressive decline in the organism function over time. It affects every organ in the body and is a significant risk for chronic diseases. Molecular hydrogen has therapeutic and preventive effects on various organs. It has antioxidative properties as it directly neutralizes hydroxyl radicals and reduces peroxynitrite level. It also activates Nrf2 and HO-1, which regulate many antioxidant enzymes and proteasomes. Through its antioxidative effect, hydrogen maintains genomic stability, mitigates cellular senescence, and takes part in histone modification, telomere maintenance, and proteostasis. In addition, hydrogen may prevent inflammation and regulate the nutrient-sensing mTOR system, autophagy, apoptosis, and mitochondria, which are all factors related to ageing. Hydrogen can also be used for prevention and treatment of various ageing-related diseases, such as neurodegenerative disorders, cardiovascular disease, pulmonary disease, diabetes, and cancer. This paper reviews the basic research and recent application of hydrogen in order to support hydrogen use in medicine for ageing prevention and ageing-related disease therapy.
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Davies, M. "Comparative ageing and age-related disease." European Geriatric Medicine 5, no. 3 (June 2014): 147–48. http://dx.doi.org/10.1016/j.eurger.2014.03.004.

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Bellantuono, Ilaria, and Paul K. Potter. "Modelling ageing and age-related disease." Drug Discovery Today: Disease Models 20 (2016): 27–32. http://dx.doi.org/10.1016/j.ddmod.2017.07.005.

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Duchac, Alexander. "Ageing related events at nuclear power plants." Natural Science 05, no. 01 (2013): 31–37. http://dx.doi.org/10.4236/ns.2013.51005.

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Navarro-Pardo, Esperanza, Ferran Suay, and Mike Murphy. "Ageing: Not only an age-related issue." Mechanisms of Ageing and Development 199 (October 2021): 111568. http://dx.doi.org/10.1016/j.mad.2021.111568.

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Dissertations / Theses on the topic "Ageing-related"

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Lau, Yuet-han Jasmine. "Ageing-related effect on emotion recognition." Click to view E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B37101730.

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Lau, Yuet-han Jasmine, and 劉月嫻. "Ageing-related effect on emotion recognition." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B37101730.

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Khan, Muhammad Tariq. "The effects of ageing on driving related performance." Thesis, University of Southampton, 2009. https://eprints.soton.ac.uk/73700/.

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According to one estimate, about 40 percent of the driving population will be over the age of 60 by the year 2020 in the UK and currently, several hundred thousand drivers with dementia hold driving licenses. The number of motor vehicle crashes per unit distance of automobile travel is “U”-shaped, with risk increasing slightly between the ages of 55 and 60, but risk increasing with each successive five-year interval. Some individuals who have mild dementia possess sufficient driving skills to be designated as fit drivers. The most challenging assessment and decision for the physician/licensing authority as regards fitness to drive lies in drivers who are questionably demented or are in a state of very mild dementia. In the absence of a reliable standard protocol, some clinicians make judgment based on selfreporting, which has risks associated with it as lack of insight and judgment are potential common traits of the population experiencing cognitive decline. Seldom is recourse made by health professionals to on-road assessment as a first alternative as it requires a fee and such testing centers are not readily available everywhere. This research addresses this issue of the identification of cognitive tests that can be used to assess an individual’s ability to drive and especially of those individuals that are questionably demented and are the most difficult to identify. A younger and an older group consisting of 56 drivers in total were administered nine different cognitive tests and two drives (Drive-I and Drive-II) on the STISIM driving simulator. The cognitive test ufov3 (involving the identification of a central target and simultaneously the radial localization of a peripheral target embedded in distracter triangles), which is the third subtest of the UFOV (Useful Field of View) test showed the highest discriminating ability in separating “poor-drivers” from “not-poor-drivers”, with 92.86 % of the drivers correctly classified. The next best discriminating ability in decreasing order of strength was that of dichotic listening test, trail making test, rey-copy test and paper folding test. Also, age was found to be an excellent discriminator of “poor-drivers” and “not-poor-drivers” with 91.07 % of the drivers correctly classified. A composite cognitive measure consisting of the sum of all nine cognitive tests was not a better predictor than the ufov3 test alone; overall it was still an excellent discriminator, classifying 89.29 % of drivers correctly. The commonly recommended Clock Drawing test and the Trail Making test did not emerge as significant predictors of driving ability. A general driving skills linear model for prediction purposes was derived that explained 59 % of the variation in a general driving performance index with the ufov3 test, the dichotic listening test and the rey-recall test as significant predictors. Recommendations are made as to how this test should be used to screen potentially at risk drivers.
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Alatawi, Fatema Suliman. "An investigation of ageing-related genomic effects of resveratrol." Thesis, University of Newcastle upon Tyne, 2013. http://hdl.handle.net/10443/1943.

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Dietary restriction (DR) increases lifespan robustly in diverse species. Effects of the dietary polyphenol resveratrol consistent with delayed ageing and/or extension of lifespan have been reported. The involvement in the longevity response to DR of the protein Sirt1, which may be activated by resveratrol and deacetylates a range of cellular substrates that includes histone proteins, identifies epigenetic processes as a pathway that may mediate effects of both DR and dietary resveratrol in delaying ageing and/or extending lifespan. Based on a preliminary observation, the hypothesis underlying the study is that some of the beneficial effects of resveratrol on lifespan/aging are mediated through effects on histone expression that oppose changes observed in ageing. A secondary hypothesis, based on a degree of structural similarity between resveratrol and 17β-oestradiol, was that epigenetic effects of resveratrol are mediated through the estrogen receptor (ER). The effect of resveratrol on histone protein expression was investigated in human intestinal Caco-2 cells and human MCF-7 breast cancer cells. Histone H2a, H2b, H3 and H4 expression was decreased in response to resveratrol treatment in both cell lines. In support of our hypothesis that resveratrol affects ageing through reversing ageing-associated changes in histone proteins, higher levels of H2A, H2B, and H4 expression were detected by western blotting in the small intestine of old (38 months) mice than in younger (12 months) mice. To investigate possible consequences of effects of resveratrol, including effects resulting from altered histone expression, we studied the effect of resveratrol on global gene expression in Caco-2 and MCF-7 cells to address several objectives including: (1) investigating if resveratrol has an effect similar to that of DR at the level of gene expression; (2) identifying if genes or pathways affected by resveratrol were also affected by manipulation of the expression level of Sirt1. For both cell types, the number of genes in the intersection between those affected by resveratrol and a compiled list of genes reported in other studies to respond to DR was greater than expected by chance, supporting the view that responses to resveratrol and to dietary restriction have some commonality and that resveratrol may mimic some effects of dietary restriction. We also found that there was very little overlap between genes affected by resveratrol treatment and by knockdown of Sirt1 expression in Caco-2 cells, which adds to accumulating evidence that resveratrol does not act through effects on Sirt1. To investigate if effects of resveratrol - in particular the reduction in histone protein expression - are mediated through the estrogen receptor (ER), Caco-2 and MCF-7 cells were treated with resveratrol in the presence or absence of the ER antagonist fulvestrant, then total cell lysate was analysed by western blotting. The reduction in histone protein (H2a, H2b, H3 and H4) expression was attenuated by fulvestrant, indicating that resveratrol reduced histone expression via an ER-dependent mechanism. For further investigation of effects of resveratrol on histone expression, Caco-2 cells were transfected with a promoter reporter construct comprising the histone H3 promoter upstream of the β- galactosidase reporter gene, and the effect on reporter gene expression of treatment with resveratrol in the presence and absence of the fulvestrant was measured. Resveratrol reduced reporter gene expression and this effect was attenuated by fulvestrant, demonstrating that resveratrol acts to reduce histone H3 expression at the level of transcription through an ER-mediated mechanism. To investigate if the response to resveratrol treatment is through interaction with estrogen response elements (EREs) in the histone H3 promoter we replaced three potential EREs within the histone H3 promoter region included in the promoter-reporter construct with random sequence. Caco-2 cells were then transfected with either original or mutated promoter-reporter construct and treated with resveratrol or the endogenous ER ligand 17-β estradiol in the presence and absence of fulvestrant. Resveratrol and 17-β estradiol both reduced reporter gene expression from both promoter reporter constructs and in all cases responses were attenuated by fulvestrant, indicating that effects of neither compound, although mediated through the ER, are on the specific sequences region we identified and replaced. In conclusion, these data indicate that resveratrol reduces histone expression in both intestinal and breast cancer cells through an ER-mediated mechanism acting at the level of transcription and that this effect may oppose an accumulation of histone proteins (observed in mouse small intestine) that accompanies ageing. With respect to effects on gene expression, resveratrol was found to mimic some effects of dietary restriction but appeared to act through a mechanism independent of Sirt1.
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Soundara, Pandi Sudha Priya. "MicroRNA in retinal ageing and age-related retinal degeneration." Thesis, Queen's University Belfast, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.675475.

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Ageing is the main risk factor for the sight threatening disease, age-related macular degeneration (AMD) which causes central vision loss. Although the exact pathogenic mechanism underlying this disease is not well known, recent advances in understanding of how gene expression is regulated suggest a role for small nOI1- coding regulatory RNAs called microRNAs. The main aims of this PhD project were to characterise the endogenous microRNAs in retinal tissues and to investigate how they change with age and in a model of AMD. In addition, how do specific microRNAs regulate retinal pigment epithelium (RPE) function. Firstly, I demonstrated that the small RNA population in three month-old C57BLl6J wild type mice retina and RPE/choroid is extremely complex, including novel orthologs and microRNAs, isomiRs, microRNAs synthesized via non-canonical via Drosha-independent pathways and other small RNAs. Secondly, expression of these microRNAs was changed with age. Half of the microRNAs expressed in polycistronic clusters change with age in the same direction. MicroRNAs altered with age were predicted to be targeting age-related pathways, retina specific functions and inflammation-related pathways, especially TGF -β signalling. Thirdly, miR-26a was highly expressed in RPE/choroid, down-regulated with age and was involved in the regulation of TGF-β signalling. Inhibition of miR-26a caused a change in YEGF expression, cell proliferation and migration . Finally, microRNAs altered in the CCLT/-/ CX3CR 1 GrP/GFP animal model of geographic atrophy were predicted to be targeting genes involved in pathways related to AMD pathology. MicroRNAs altered at before an overt phenotype in this model animal also targeted some of these pathways and may be a prelude to this disease pathology. Some of the microRNA changed with age overlap with this animal model suggesting that microRNA changes in retina contribute to .disease progression. Alhough miR-26a expression changes in this model are not significant. Functional changes with miR- 26a inhibition suggest its potential as a future biomarker for ageing and a therapeutic approach for age related macular degeneration. Thus, microRNAs playa major role in ageing and age-related retinal degeneration.
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Tsai, Pei-Chien. "Epigenetic determinants of healthy ageing and age-related disease risk." Thesis, King's College London (University of London), 2015. https://kclpure.kcl.ac.uk/portal/en/theses/epigenetic-determinants-of-healthy-ageing-and-agerelated-disease-risk(8a338def-2d32-4bc3-a0bd-7ced65efc679).html.

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Epigenome-wide association scans (EWAS) of human complex traits are a rapidly growing area of research, in part due to recent advances in technology that have allowed for a deeper coverage of the human methylome. One of the unique features of the human methylome is that it is dynamic and previous studies have shown that age can have a strong impact on DNA methylation patterns. The dynamic nature of DNA methylation also influences EWAS methodology, both from a statistical and biological perspective. In this thesis, I explored EWAS methods and applications to ageing and age-related phenotypes. Firstly, I estimated EWAS power under several simulation scenarios and study designs, and my results suggested that the majority of recent EWAS studies lack statistical power to detect small DNA methylation effect sizes. I then applied EWAS to identify differential methylation CpG sites associated with three phenotypes, including ageing, birth weight and smoking. One of the novel findings from this thesis was that hundreds of genome-wide significant ageing-related hypermethylated regions were identified across multiple tissues in twins. These findings confirm and extend previous work showing that ageing has a strong underlying effect on DNA methylation. Birth weight did not yield significant differential methylation sites, which may be partly explained by low power to detect modest methylation effects. Smoking is a well-known environmental risk factor for disease, and my analyses identified novel impacts of smoking on DNA methylation patterns in adipose tissue, which are of interest to cardiovascular and metabolic disease. I further explored the impacts of smoking by integrating DNA methylation and gene expression profiles in adipose tissue and in whole blood. In addition to identifying novel results, my findings also confirmed that the AHRR and F2RL3 genes showed stable and consistent changes related to smoking in both DNA methylation and gene expression profiles across tissues. My findings explored methodological issues in genome-wide methylation studies and showed that age and smoking have a strong and reproducible effect on DNA methylation across tissues in humans, which suggests that these factors should always be included as covariates in EWAS of human complex traits.
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Perales, Puchalt Jaime 1985. "Health and ageing : Active ageing in older adults and health related quality of life in people with dementia." Doctoral thesis, Universitat Pompeu Fabra, 2014. http://hdl.handle.net/10803/286877.

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The continuing growth of older age groups worldwide needs an increased understanding of the ageing phenomena. For this reason, the present thesis is aimed at two very important outcomes in the elderly, active ageing (AA) in older adults and health-related quality of life (HRQL) in people with dementia. To do this, I have participated in different studies and used different research methodologies. In the first publication of this thesis, I study the distribution and associations with sociodemographic variables of different definitions of AA in a large adult population sample in Spain, Poland and Finland. The next publication reviews the previous literature on HRQL instruments for dementia in order to understand such complex concept and compare the different instruments in terms of for example data collection method or purpose of assessment. In the last publication, I explore the distribution of HRQL in the very old population in Cambridge by creating a new instrument using an already existing conceptual framework. Note: data from Courage Project (http://www.courageineurope.eu/) used for the thesis.
El continuo envejecimiento de la población mundial hace que sea necesario entender mejor este fenómeno. Por esta razón, la presente tesis doctoral tiene como objetivo estudiar dos variables muy importantes en la gente mayor, envejecimiento activo (AA) en la gente mayor y calidad de vida relacionada con la salud (HRQL) en gente con demencia. Para ello, he participado en diferentes estudios y he utilizado diferentes metodologías de investigación. En la primera publicación de esta tesis, estudio la distribución y asociación de diferentes definiciones de AA con variables sociodemográficas en una amplia muestra poblacional de España, Polonia y Finlandia. En la siguiente publicación llevo a cabo una revisión de la literatura sobre instrumentos para medir HRQL en demencia con tal de entender este complejo concepto y comparar los diferentes instrumentos en cuanto al método de recogida de información o al motivo de evaluación, por ejemplo. En la ultima publicación, exploro la distribución de HRQL en la población de gente muy mayor de Cambridge, creando un nuevo instrumento utilizando un marco conceptual ya existente. Nota: se usan los datos del Proyecto Courage (http://www.courageineurope.eu/).
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Sacitharan, Pradeep. "Linking ageing and arthritis : the role of the longevity-related SIRT1 molecule in age-related cartilage degeneration and osteoarthritis." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:cb519867-d184-44ff-b17f-bee1974f430b.

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Osteoarthritis (OA) is the most common form of arthritis worldwide and is characterised by the progressive degradation of articular cartilage. Ageing is the primary risk factor associated with OA. However, the roles of ageing-related mechanisms in cartilage homeostasis are poorly understood. The class three histone deacetylase, Silent mating type information regulation 2 homolog (SIRT1) has been extensively shown to regulate lifespan in lower organisms and signalling pathways linked to mammalian ageing. My thesis explores the role of Sirtuin 1 in cartilage homeostasis and OA. I used in vitro experiments with chondrocyte cell lines, human clinical samples, novel genetically modified cartilage specific and whole body SIRT1 deficient mice alongside molecular biological tools to investigate my research questions. Human OA cartilage showed decreased SIRT1 compared to healthy cartilage. Mice with cartilage-specific SIRT1 deletion showed greater cartilage degradation during ageing and in an experimental OA model. In vitro and in vivo studies showed SIRT1 to directly regulate autophagy in chondrocytes. More importantly, the activation of autophagy using spermidine protected against experimental OA in wild-type mice but not in cartilage-specific SIRT1 deficient mice. In addition, my data revealed whole body SIRT1 deficient mice had increased early joint inflammation in repose to injury but displayed less cartilage loss over time in an experimental OA model. Together I have shown that SIRT1 declines with age and contributes to OA due to dysregulated autophagy. However, chronic low grade inflammation caused by SIRT1 loss was protective. My data suggest these pathways can be targeted to treat OA.
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Zierer, Jonas. "Integrative analysis of the metabolic signatures of ageing and age-related diseases." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/integrative-analysis-of-the-metabolic-signatures-of-ageing-and-agerelated-diseases(b76bf26f-2cc0-4aff-b02a-d5805316697a).html.

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Ageing is a complex process and is the strongest risk factor for many diseases. To elucidate processes underlying biological ageing, many studies have investigated the associations of individual metabolites or genes with age and age-related phenotypes. While these studies improved our understanding of the pathogenic mechanisms for many diseases, they have their limitations. Analysing phenotypes separately in classical association studies typically neglects relationships and interactions between and across different phenotypes (e.g. comorbidities), genes (e.g. pleiotropy), and metabolites (e.g. through shared biochemical pathways). The aim of this thesis was to better understand age-related phenotypes and their interdependencies through exploring shared underlying processes. To this end, I first identified biomarkers of ageing and age-related diseases, focusing on chronic kidney disease, using metabolomics and glycomics technologies. I identified several metabolites associated with leukocyte telomere length, a common marker of biological ageing. Then I investigated the associations of molecular phenotypes with renal disease. Analysing metabolomic profiles associated with renal function in diabetic and non-diabetic cohorts illustrated similarities between the different aetiologies of kidney disease, such as the lack of renal conversion of amino acids, but also differences, particularly of lipid and energy metabolism. Subsequent analyses identified changes of Immun-oglobin G glycosylation as a novel inflammatory pathway involved in renal disease. Then, I assessed the potential of the faecal metabolome as a functional readout of the gut microbial community to investigate its association with biological ageing. While faecal metabolites were only moderately associated with age and renal function, they showed great potential as novel profiling method for studying the microbiome, particularly with respect to obesity. Next, I integrated metabolomics data from plasma, urine, and saliva to model cross-fluid metabolism individually for kidney disease patients and healthy controls. By comparing both models, I identified metabolic key processes impaired in kidney disease. Finally, I integrated metabolomic and glycomic biomarkers of ageing with other omics markers as well as extensive phenotypic data to investigate their multivariate interdependencies, underlying the comorbidities of age-related diseases. This comprehensive integration of age-related phenotypes highlighted several molecular mechanisms that potentially cause the joint occurrence of diseases with age. Con-sidering the complex aetiologies of different diseases and their dependencies will be needed to facilitate personalised healthcare. In conclusion, I have shown the future potential of sys-tems and network biology approaches for understanding disease mechanisms and precision medicine.
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Harris, Mathew Alan. "Navigational strategy switching in ageing." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/10066.

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With advancing age, many cognitive faculties deteriorate, and navigation abilities may be among those most affected. The majority of previous work investigating navigation impairments in ageing has focused on allocentric processing, attributing deficits to hippocampal dysfunction. However, real-world navigation is dependent upon numerous different strategies, as well as the ability to flexibly switch between them. Outside the context of navigation, it has been demonstrated that strategy switching, thought to be coordinated by regions of prefrontal cortex and the locus coeruleus-noradrenergic system, is also susceptible to the effects of ageing. Deficits in navigational strategy switching, and prefrontal or noradrenergic dysfunction, are therefore also likely to contribute to age-related navigation impairments. The work presented in this thesis aimed to explore age-related impairments in strategy switching within the context of navigation, and the underlying neural mechanisms in terms of a prefrontal-noradrenergic model of switching. The studies presented in Chapter Three assessed the use of allocentric and egocentric navigational strategies by young and older people. Older participants tended to use an egocentric strategy where an allocentric strategy was required, possibly due to a difficulty in switching to the appropriate allocentric strategy. In Chapter Four, I provide an account of two studies directly assessing navigational strategy switching, using two different tasks based in virtual reality. The first study utilised a virtual adaptation of the plus maze task, involving switching between an allocentric place strategy and an egocentric response strategy, and demonstrated that older participants were specifically impaired at switching to the place strategy. The second study used a more realistic task set in a virtual town environment, which involved switching from an egocentric route-following strategy to an allocentric wayfinding strategy, and also demonstrated an age-related deficit in switching to an allocentric strategy. In Chapter Five, I begin to explore the mechanisms underlying impaired navigational strategy switching in ageing. Firstly, I describe a further behavioural study that used variants of the virtual plus maze and a navigational gambling task to demonstrate a contribution of impaired decision making to the deficit in switching to an allocentric strategy. This indicates that the deficit can be attributed, at least in part, to prefrontal dysfunction. A second study presented in the same chapter demonstrated that practising orienteering does not protect against decline in navigational strategy switching ability with ageing. Chapter Six provides an account of my direct assessment of the neural bases of navigational strategy switching using functional magnetic resonance imaging. In young subjects, I found some evidence in support of the roles of prefrontal regions in navigational strategy switching. However, I was unable to complete development of a task suitable for assessing age differences in functional activation of brain regions involved in navigational strategy switching. The final experimental study, included in Chapter Seven, assessed pupil size and heart rate as physiological correlates of noradrenergic activity during performance of the virtual plus maze. Both young and old participants demonstrated a noradrenergic response to all strategy changes, suggesting that impairments are more likely attributable to dysfunction of prefrontal cortex than of the locus coeruleus, although some subtle effects suggested that noradrenergic dysfunction does have some effect on navigational strategy switching deficits. In the same chapter, I report the results of a meta-analysis of data from five of the preceding studies, suggesting that deficits in both strategy switching and allocentric processing combine to produce a greater impairment in switching to an allocentric strategy. The main finding of this series of studies is that navigational strategy switching is impaired in ageing, which may contribute to the more widely reported difficulties that older people have with navigation. My work also provides evidence in support of a prefrontal-noradrenergic model of navigational strategy switching, and suggests that dysfunction of prefrontal cortex and, to a lesser extent, the locus coeruleus-noradrenergic system is responsible for decline in navigational strategy switching ability with ageing. In conclusion, this thesis draws attention to the important role of deficient executive processing and dysfunction of extra-hippocampal brain regions in age-related navigation impairments.
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Books on the topic "Ageing-related"

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Uzielli, Luca, ed. Wood Science for Conservation of Cultural Heritage – Florence 2007. Florence: Firenze University Press, 2010. http://dx.doi.org/10.36253/978-88-8453-396-8.

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COST Action IE0601 "Wood Science for Conservation of Cultural Heritage" (www.woodculther.org) aims to improve the conservation (including study, preventive conservation and restoration) of European Wooden Cultural Heritage Objects (WCHOs), by fostering targeted research and multidisciplinary interaction between Researchers in various fields of Wood Science, Conservators of wooden artworks, other Scientists from related fields. This book of Proceedings contains most of the papers presented in the International Conference held in Florence (Italy) on 8-10 November 2007, dealing with several of the Action's themes, including structure and properties of historic wood, ageing and non-biological degradation of wood material, contributions from Wood Science to conservation issues.
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Recommendations on Ageing-Related Statistics. United Nations, 2017. http://dx.doi.org/10.18356/d75677cd-en.

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Inui, Akio, Masahiro Ohsawa, and Yasuhito Uezono, eds. Ageing-Related Symptoms, Kampo Medicine and Treatment. Frontiers Media SA, 2021. http://dx.doi.org/10.3389/978-2-88971-925-9.

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Durrleman, Stanley, Daniel C. Alexander, Ninon Burgos, Holger Fröhlich, Neil P. Oxtoby, and Viktor Wottschel, eds. Computational Approaches for Ageing and Age-related diseases. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-766-3.

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Visual Attention-Related Processing: Perspectives from Ageing, Cognitive Decline and Dementia. MDPI, 2021. http://dx.doi.org/10.3390/books978-3-0365-0985-3.

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Youthing - How To Reverse The Ageing Process And Cure Age Related Diseases. Harald W. Tietze Publishing, 2006.

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Smentek, Daniel. Management of an ageing workforce: How employers can deal with related challenges. VDM Verlag Dr. Mueller e.K., 2007.

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European design for ageing network: Incorporating age-related issues into design courses : teaching pack. [S.l.]: [s.n.], 1995.

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Zanto, Theodore P., and Adam Gazzaley. Attention and Ageing. Edited by Anna C. (Kia) Nobre and Sabine Kastner. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199675111.013.020.

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This chapter addresses how normal ageing may affect selective attention, sustained attention, divided attention, task-switching, and attentional capture. It is not clear that all aspects of attention are affected by ageing, especially once changes in bottom-up sensory deficits or generalized slowing are taken into account. It also remains to be seen whether deficits in these abilities are evident when task demands are increased. Age-based declines have been reported during many tasks with low cognitive demands on various forms of attention. Fortunately, the older brain retains plasticity and cognitive training and exercise may help reduce negative effects of age on attention. Although no single theory of cognitive ageing may account for the various age-related changes in attention, many aspects have been taken into account, such as generalized slowing, reduced inhibitory processes, the retention of performance abilities via neural compensation, as well as declines in performance with increased task difficulty.
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Michel, Jean-Pierre, B. Lynn Beattie, Finbarr C. Martin, and Jeremy Walston, eds. Oxford Textbook of Geriatric Medicine. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198701590.001.0001.

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The 3rd Edition of The Oxford Textbook of Geriatric Medicine brings together specialists from across the globe to provide every physician and health care provider involved in the care of older people with a comprehensive resource on the medical, social, and psychological issues they are likely to encounter in their practice and research. Beyond these issues, this comprehensive text provides insights into global population ageing, ageing-relevant policy developments, healthy ageing, lifecourse, multimorbidity, personalised and person-centred care.New material has been added throughout with a strong focus on integrating the impact of age-related physiological and cellular changes with the development of age-related diseases and conditions. Sections on sarcopenia, nutritional health, frailty and related geriatric syndromes have been expanded. Geriatric care principles from public health, primary and specialized care have also been updated and expanded. New models of care in general medicine and surgery and related sub-specialties, outpatient and emergency care, rehabilitation, oncology, palliative medicine and long-term care relevant to older adults are discussed in detail. In summary, the 3rd Edition of The Oxford Textbook of Geriatric Medicine 3e articulates important new global demographic trends and clinical practice patterns, the scientific basis of age-related diseases and conditions, and the ethical, legal, and socioeconomic concerns for healthcare policy and systems relevant to older adults around the globe.
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Book chapters on the topic "Ageing-related"

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Kalaria, Raj N., and Yoshiki Hase. "Neurovascular Ageing and Age-Related Diseases." In Subcellular Biochemistry, 477–99. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-3681-2_17.

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Denenberg, Sagi. "Ageing-related problems in cats and dogs." In Small animal veterinary psychiatry, 263–77. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781786394552.0263.

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Denenberg, Sagi. "Ageing-related problems in cats and dogs." In Small animal veterinary psychiatry, 263–77. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781786394552.0016.

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Chen, Chuan, Zheng Cao, Hehua Lei, and Limin Zhang. "The Gut Microbiota and Its Metabolites Contribute to Ageing and Ageing-Related Diseases." In Healthy Ageing and Longevity, 3–22. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-14023-5_1.

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Singh, Rameshwar. "Electrophysiological Ageing of the Brain: Ageing-Related Impairments in Neural and Cognitive Functions." In Topics in Biomedical Gerontology, 291–301. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-2155-8_16.

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Bueno, Valquiria, and Graham Pawelec. "Myeloid-Derived Suppressive Cells in Ageing and Age-Related Diseases." In Healthy Ageing and Longevity, 53–64. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-87532-9_4.

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Delori, F. C. "RPE lipofuscin in ageing and age-related macular degeneration." In Documenta Ophthalmologica Proceedings Series, 37–45. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5137-5_7.

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Dikshit, Reetika, Pragya Lodha, and Avinash De Sousa. "Ageing Related Mental Health Issues in the LGBTQ+ Community." In Gerontological Concerns and Responses in India, 269–82. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-4764-2_16.

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Franceschi, Claudio, Zelda Alice Franceschi, Paolo Garagnani, and Cristina Giuliani. "Inflammaging and Its Role in Ageing and Age-Related Diseases." In Evolutionary Thinking in Medicine, 259–75. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29716-3_18.

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Vida, Carmen, and Mónica De la Fuente. "Stress-related Behavioural Responses, Immunity and Ageing in Animal Models." In Immunosenescence, 125–44. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4776-4_8.

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Conference papers on the topic "Ageing-related"

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de Pablo, A. "Furfural and ageing: how are they related." In IEE Colloquium Insulating Liquids. IEE, 1999. http://dx.doi.org/10.1049/ic:19990667.

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Yuan, Xiaosong, Ruoyang Hong, and Danyating Shen. "A Deeper Understanding of Modular DNN in Predicting Ageing-Related Disease." In DMIP '21: 2021 4th International Conference on Digital Medicine and Image Processing. New York, NY, USA: ACM, 2021. http://dx.doi.org/10.1145/3506651.3506659.

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Shi, Jie, Xinming Jin, Zhiming Liu, Haining Shi, Jianlin Yao, and Fengsheng Tu. "Ageing Assessment, Condition Inspection and Lifetime Evaluation for Safety Related Fuse in Nuclear Power Plant." In 18th International Conference on Nuclear Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/icone18-29013.

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This paper presents the ageing mechanism of fuse in nuclear power plant in detail. Metal Electromigration is identified as the dominant ageing mechanism. On this basis, the dominant status indicators, temperature and resistance of fuse were ensured, and current-temperature curve was proposed. The infrared thermal imaging technology was used to inspect the ageing condition and prove the current-temperature curve. Finally, the accelerated ageing testing was conducted abiding by the dominant ageing mechanism, and the lifetime was evaluated.
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Florescu, Gheorghe, and Mihail Cojan. "Identification of CSSC Caused by Ageing and Degradation." In 14th International Conference on Nuclear Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/icone14-89286.

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PSA studies, that were developed for some NPPs, permit the using of the created models to perform many research tests, in order to optimize the structures, systems and components (SSCs) operation or to identify the NPP or systems weaknesses, due to specific or special factors. SSCs that influence decisively the NPP reliability are considered as critical. Also, for the accident conditions, the SSC, which have a major influence to the system availability or operability, are considered as critical. Many worldwide NPPs reached the life time or are very close to do that. Several SSCs have shorter life times than NPP’s life time. Ageing is one of the factors that decrease the SSC life time. Due to ageing, if are not replaced, some SSCs, or groups of redundant SSCs, become critical looking to safety. Some questions for what to do in the situation when a SSC must be replaced and the SSC specific manufacturer doesn’t exist, could also be put. The paper tried to solve the problem of SSC modeling by introducing of an ageing factor in SSC model. Fault tree (F/T) modeling approach is assumed. There are two possibilities for modeling: failure rates that are changed or specific MCS (minimal cut set) term modified by ageing. Risk analysis and PSA techniques are used as a basis for analysis. The paper includes: the steps to establish the systems or components that suffer ageing; methods to identify CSSC taking into account ageing; the events associated to ageing/degradation and presentation of method to determine the ageing related events, selection of the SSCs that are important for analyses; selection of the most significant ageing events; ranking of ageing events; association of events to these components in order to decide for the CSSC detailed analyses; ranking / ordering of the ageing related events; optimization of NPP systems design and operation considering ageing; impact of ageing to NPP operation/safety/safety margins and to manufacturer technical specifications. The paper presents a brief description of the most important aspects of the methods, used to analyze the ageing effects on appearing of CSSCs, taking into account the previous developed NPP PSA models and PSA modeling tools.
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German, Ronan, Ali Sari, Pascal Venet, Olivier Briat, and Jean-Michel Vinassa. "Study of static converters related ripple currents effects on supercapacitors ageing within DC networks." In 2015 IEEE 24th International Symposium on Industrial Electronics (ISIE). IEEE, 2015. http://dx.doi.org/10.1109/isie.2015.7281660.

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Guzzi, Pietro Hiram, Ugo Lomoio, Rocco Scicchitano, and Pierangelo Veltri. "NOMA-DB: a framework for management and analysis of ageing-related gene-expression data." In 2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2022. http://dx.doi.org/10.1109/bibm55620.2022.9994891.

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Ho¨rnlund, Erik, Gerhard Ersdal, Rolf H. Hinderaker, Roy Johnsen, and John Sharp. "Material Issues in Ageing and Life Extension." In ASME 2011 30th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2011. http://dx.doi.org/10.1115/omae2011-49363.

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A considerable number of the structures in the Norwegian part of the North Sea have passed or are close to their design life. Material degradation will play an important role in the ageing of these structures and the evaluation of their safety. An overview of research work initiated by the Petroleum Safety Authority (PSA) is presented. The paper focuses on various material aspects of ageing related to offshore facilities, the risks they represent to the integrity of a facility and how to deal with them in a life extension process. The paper presents and discusses expectations towards the industry with respect to evaluation of ageing materials in life extension.
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Bentrcia, Toufik, Faycal Djeffal, and Hichem Ferhati. "An ANFIS-based Computation to Study the Degradation-related Ageing effects in Nanoscale GAA-TFETs." In ICIST '20: 10th International Conference on Information Systems and Technologies. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3447568.3448546.

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Buffagni, Alessia, Martina Frausin, and Giampiero Dalai. "DESIGN EDUCATION FOR A HEALTHIER AGEING: DESIGN STUDENTS EXPLORE MULTIMORBIDITY, A WIDESPREAD AGE-RELATED CONDITION." In 14th International Conference on Education and New Learning Technologies. IATED, 2022. http://dx.doi.org/10.21125/edulearn.2022.0548.

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Hou, Fei, Lili Cao, and Qi Wang. "Call for the Ageing-inclusive Digital Economy and Related Standards: Based on a Global Survey." In ICEME 2022: 2022 13th International Conference on E-business, Management and Economics. New York, NY, USA: ACM, 2022. http://dx.doi.org/10.1145/3556089.3556175.

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Reports on the topic "Ageing-related"

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Valente Rosa, Maria João. Demographic ageing: the rigidity of conventional metrics and the need for their revision. IPR-NOVA, January 2022. http://dx.doi.org/10.23906/wp63/2022.

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This article aims to discuss the scope and value of the conventional metrics used to assess and compare levels of ageing between different populations. The age brackets for classifying if the population is ageing or aged are typically based on chronological age and are very close to the stages of the economic tripartite life cycle: the school/education phase; the labour market participation phase; the retirement phase. Those conventional metrics produce distortions in capturing the levels of demographic ageing. If the change in the age structure is rooted in social development, not in a social crisis, having more people in older ages should be related to that. Living longer, on average, does not only mean living more years but also a change in people's social profile, which the usual metrics for measuring ageing do not capture. Because of the central place that demographic ageing occupies in the framework of social, political and scientific reflection on the present and future of societies, Demographic Science should contribute with new metrics reflecting the real social improvements in populations age structures. This reflection supports the need to undertake a critical analysis of the way demographic ageing has usually been presented; stresses the need to advance ageing metrics that match societies' development by considering the life expectancy; and presents a new indicator for measurement demographic ageing that compares what we observe with what we can expect from the age structure at any given mortality level.
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Stjernberg, Mats, Hjördís Rut Sigurjónsdóttir, and Mari Wøien Meijer. Unlocking the potential of silver economy in the Nordic Region. Nordregio, March 2021. http://dx.doi.org/10.6027/r2021:7.1403-2503.

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This report focuses on the concept of the silver economy, which has emerged as a response to population ageing in Europe in recent years. The silver economy refers to all economic activities linked to older age groups. The concept is based on the notion that many older people continue to make valuable economic and societal contributions after retirement, and that older citizens can provide significant economic and societal benefits, particularly if they are healthy and active. This report examines policies and initiatives to promote the silver economy and the closely related concepts of healthy ageing, active ageing and age-friendliness. The report seeks to uncover what are the preconditions for expanding the Nordic silver economy, and how cross-border collaboration can help enhance the potential of the silver economy in border regions.
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Ward, Mark, Christine McGarrigle, and Orna Donoghue. Irish adults transition to retirement – wellbeing, social participation and health-related behaviours. Findings from The Irish Longitudinal Study on Ageing (TILDA). The Irish Longitudinal Study on Ageing, February 2019. http://dx.doi.org/10.38018/tildare.2019-00.

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