Academic literature on the topic 'AECOPD'

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Journal articles on the topic "AECOPD"

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Citgez, Emanuel, Job van der Palen, Paul van der Valk, Huib A. M. Kerstjens, and Marjolein Brusse-Keizer. "Stability in eosinophil categorisation during subsequent severe exacerbations of COPD." BMJ Open Respiratory Research 8, no. 1 (August 2021): e000960. http://dx.doi.org/10.1136/bmjresp-2021-000960.

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BackgroundThe blood eosinophil count has been shown to be a promising biomarker for establishing personalised treatment strategies to reduce corticosteroid use, either inhaled or systemic, in chronic obstructive pulmonary disease (COPD). Eosinophil levels seem relatively stable over time in stable state, but little is known whether this is also true in subsequent severe acute exacerbations of COPD (AECOPD).Aims and objectivesTo determine the stability in eosinophil categorisation between two subsequent severe AECOPDs employing frequently used cut-off levels.MethodsDuring two subsequent severe AECOPDs, blood eosinophil counts were determined at admission to the hospital in 237 patients in the Cohort of Mortality and Inflammation in COPD Study. The following four cut-off levels were analysed: absolute counts of eosinophils ≥0.2×10⁹/L (200 cells/µL) and ≥0.3×10⁹/L (300 cells/µL) and relative eosinophil percentage of ≥2% and ≥3% of total leucocyte count. Categorisations were considered stable if during the second AECOPD their blood eosinophil status led to the same classification: eosinophilic or not.ResultsDepending on the used cut-off, the overall stability in eosinophil categorisation varied between 70% and 85% during two subsequent AECOPDs. From patients who were eosinophilic at the first AECOPD, 34%–45% remained eosinophilic at the subsequent AECOPD, while 9%–21% of patients being non-eosinophilic at the first AECOPD became eosinophilic at the subsequent AECOPD.ConclusionsThe eosinophil variability leads to category changes in subsequent AECOPDs, which limits the eosinophil categorisation stability. Therefore, measurement of eosinophils at each new exacerbation seems warranted.
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Stone, Philip, Nikhil Sood, Johanna Feary, C. Michael Roberts, and Jennifer K. Quint. "Validation of acute exacerbation of chronic obstructive pulmonary disease (COPD) recording in electronic health records: a systematic review protocol." BMJ Open 10, no. 2 (February 2020): e032467. http://dx.doi.org/10.1136/bmjopen-2019-032467.

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IntroductionMany patients with chronic obstructive pulmonary disease (COPD) experience a sustained worsening in symptoms termed an acute exacerbation (AECOPD). AECOPDs impact on patients’ quality of life and lung function, are costly to health services and are an important topic for research. Electronic health records (EHR) are increasingly being used to study AECOPD, requiring accurate detection of AECOPD in EHRs to ensure generalisable results. The aim of this protocol is to provide an overview of studies that validate AECOPD definitions used in EHRs and administrative claims databases.Methods and analysisMedline and Embase will be searched for terms related to COPD exacerbation, EHRs and validation. All studies published between 1 January 1990 and 30 September 2019 written in English that validate AECOPD in EHRs and administrative claims databases will be considered. Inclusion criteria: EHR data must be routinely collected; the AECOPD detection algorithm must be compared against a reference standard; and a measure of validity must be calculable. Two independent reviewers will screen articles for inclusion, extract study details and assess risk of bias using QUADAS-2. Disagreements will be resolved by consensus or arbitration by a third reviewer. This protocol has been developed in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols checklist.Ethics and disseminationThis will be a review of previously published literature therefore no ethical approval is required. Results from this review will be published in a peer-reviewed journal. The results can be used in future research to identify occurrences of AECOPD.PROSPERO registration numberCRD42019130863.
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Nguyen, Huong Q., Richard A. Mularski, Marilyn L. Moy, Janet S. Lee, and Ernest Shen. "Association between self-reported moderate to vigorous physical activity and the rate of outpatient treated COPD exacerbations: retrospective cohort study." BMJ Open Respiratory Research 7, no. 1 (May 2020): e000590. http://dx.doi.org/10.1136/bmjresp-2020-000590.

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IntroductionLittle has been published regarding the relationship between physical activity (PA) and outpatient treated, mild to moderate acute exacerbation of chronic obstructive pulmonary disease exacerbations (AECOPD). The purpose of this study was to determine the association between self-reported PA and outpatient treated AECOPD over 2 years using real-world data obtained from existing electronic medical records (EMRs).MethodsWe included 44 896 patients with a chronic obstructive pulmonary disease diagnosis from the EMR in this retrospective cohort study. Moderate to vigorous PA was measured via patient self-report, obtained during routine clinical care; patients were classified as inactive (0 min/week), insufficiently active (1–149 min/week) or active (≥150 min/week). AECOPDs were measured using both encounter and prescription fill (antibiotics and/or oral steroids) data. We used Poisson regression models to compare the unadjusted and adjusted rates of outpatient treated AECOPD over 2 years across the PA categories.ResultsIn adjusted models, the 2-year AECOPD incidence rate ratio (IRR) was not different between the inactive and insufficiently inactive groups (IRR 0.98, 95% CI 0.96 to 1.01) and only marginally meaningful lower for the active group (IRR 0.97, 95% CI 0.95 to 0.98). Sensitivity analyses of patients meeting or not meeting obstructive criteria produced similar results with generally weak or non-significant associations.ConclusionThe lack of an association between PA and AECOPD contrasts with previous published findings of a strong relationship between moderate to vigorous PA and hospitalisations for severe AECOPD. This difference could partially be attributed to the imprecision of our measurements for both the exposure and outcome.
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MacDonald, Martin I., Christian R. Osadnik, Lauren Bulfin, Elizabeth Leahy, Paul Leong, Eskandarain Shafuddin, Kais Hamza, Paul T. King, and Philip G. Bardin. "MULTI-PHACET: multidimensional clinical phenotyping of hospitalised acute COPD exacerbations." ERJ Open Research 7, no. 3 (June 3, 2021): 00198–2021. http://dx.doi.org/10.1183/23120541.00198-2021.

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BackgroundThe generic term “exacerbation” does not reflect the heterogeneity of acute exacerbations of COPD (AECOPD). We utilised a novel algorithmic strategy to profile exacerbation phenotypes based on underlying aetiologies.MethodsPatients hospitalised for AECOPD (n=146) were investigated for aetiological contributors summarised in a mnemonic acronym ABCDEFGX (A: airway virus; B: bacterial; C: co-infection; D: depression/anxiety; E: eosinophils; F: failure (cardiac); G: general environment; X: unknown). Results from clinical investigations were combined to construct AECOPD phenotypes. Relationships to clinical outcomes were examined for both composite phenotypes and their specific aetiological components. Aetiologies identified at exacerbation were reassessed at outpatient follow-up.ResultsHospitalised AECOPDs were remarkably diverse, with 26 distinct phenotypes identified. Multiple aetiologies were common (70%) and unidentifiable aetiology rare (4.1%). If viruses were detected (29.5%), patients had longer hospitalisation (7.7±5.6 versus 6.0±3.9 days, p=0.03) despite fewer “frequent exacerbators” (9.3% versus 37%, p=0.001) and lower mortality at 1 year (p=0.03). If bacterial infection was found (40.4%), patients were commonly “frequent exacerbators” (44% versus 18.4%, p=0.001). Eosinophilic exacerbations (28%) were associated with lower pH (7.32±0.06 versus 7.36±0.09, p=0.04), higher venous carbon dioxide tension (PvCO2) (53.7±10.5 versus 48.8±12.8, p=0.04), greater noninvasive ventilation (NIV) usage (34.1% versus 18.1%) but shorter hospitalisation (4 (3–5) versus 6 (4–9) days, p<0.001) and lower infection rates (41.4% versus 80.9%, p<0.0001). Cardiac dysfunction and severe anxiety/depression were common in both infective and non-infective exacerbations. Characteristics identified at exacerbation often persisted after recovery.ConclusionsHospitalised AECOPDs have numerous causes, often in combination, that converge in complex, multi-faceted phenotypes. Clinically important differences in outcomes suggest that a phenotyping strategy based on aetiologies can enhance AECOPD management.
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Dai, Guangming, Yajuan Ran, Jiajia Wang, Xingru Chen, Junnan Peng, Xinglong Li, Huojin Deng, Min Xiao, and Tao Zhu. "Clinical Differences between Eosinophilic and Noneosinophilic Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Multicenter Cross-Sectional Study." Mediators of Inflammation 2020 (November 12, 2020): 1–9. http://dx.doi.org/10.1155/2020/1059079.

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Rationale. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is highly heterogeneous with a plethora of different etiologic factors and inflammatory presentations. COPD with higher blood eosinophil count is associated with increased readmission rates and better corticosteroid responses. However, the clinical features of eosinophilic AECOPD are not well explored. Thus, this study was aimed at exploring the clinical differences between eosinophilic and noneosinophilic AECOPD. Methods. A total of 643 AECOPD patients were enrolled in this multicenter cross-sectional study. Finally, 455 were included, 214 in the normal-eosinophil AECOPD (NEOS-AECOPD) group, 63 in the mild increased-eosinophil AECOPD (MEOS-AECOPD) group, and 138 in the severe increased-eosinophil AECOPD (SEOS-AECOPD) group. Demographic data, underlying diseases, symptoms, and laboratory findings were collected. Multiple logistic regression analysis was performed to identify the independent factors associated with blood eosinophils (EOS). Correlations between blood EOS and its associated independent factors were evaluated. Results. The significant differences in 19 factors, including underlying diseases, clinical symptoms, and laboratory parameters, were identified by univariate analysis. Subsequently, multiple logistic regression analysis revealed that lymphocyte%, neutrophil% (NS%), procalcitonin (PCT), and anion gap (AG) were independently associated with blood EOS in AECOPD. Both blood EOS counts and EOS% were significantly correlated with lymphocyte%, NS%, PCT, and AG. Conclusions. Collectively, blood EOS was independently associated with lymphocyte%, NS%, PCT, and AG in AECOPD patients. Lymphocyte% was lower, and NS%, PCT, and AG were higher in eosinophilic AECOPD. Our results indicate that viral-dominant infections are the probable major etiologies of eosinophilic AECOPD. Noneosinophilic AECOPD is more likely associated with bacterial-dominant infections. The systemic inflammation in noneosinophilic AECOPD was more severe.
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Guo, Xuequn, Hongsheng Lin, Donghao Guo, and Qiu Luo. "Azithromycin use prior to ICU admission is associated with a lower short-term mortality for critically ill acute exacerbations of chronic obstructive pulmonary disease patients: A retrospective cohort study." Chronic Respiratory Disease 19 (January 2022): 147997312211407. http://dx.doi.org/10.1177/14799731221140797.

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Azithromycin was thought to prevent acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) by anti-microbial and anti-inflammatory effects. However, it′s value in the treatment of critically ill patients with AECOPD before ICU admission remains unclear. Our study aimed to find whether azithromycin use prior to ICU admission leads to better clinical outcomes for those individuals. 533 critically ill patients with AECOPD from the MIMIC-IV database were included. Univariate followed multivariate logistic regression was used to select risk factors for short-term mortality. The multivariable logistic regression models were implemented to investigate the association between azithromycin use before ICU admission and short-term mortality. Lower short-term mortality was observed in the azithromycin group ( p = .021), independent of differences in demographic data and other clinical outcomes ( p>.05). Azithromycin use before ICU admission was proved to have a decreased short-term mortality by multivariable logistic regression ( p<.05). The results remained consistent after being stratified by age, SOFA scores, pH, and cancer diagnosis. Azithromycin use prior to ICU admission was associated with lower short-term mortality for critically ill AECOPD patients.
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Guo, Wei, Ning Wang, Zhaobo Cui, Wenjing Liu, Shufen Guo, Xiaoya Yang, Yajing Liu, Liye Shao, and Jing Wang. "Clinical Value of FeNO for Pulmonary Hypertension Diagnosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease." Emergency Medicine International 2022 (January 28, 2022): 1–6. http://dx.doi.org/10.1155/2022/9924047.

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Objective. To investigate the clinical value of fractional exhaled nitric oxide (FeNO) in the diagnosis of pulmonary hypertension (PH) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods. In this study, the medical records of AECOPD patients were retrospectively reviewed. The patients were divided into AECOPD and AECOPD + PH groups based on the absence or presence of PH. Moreover, FeNO and other indexes were compared between the two groups. The value of FeNO in diagnosing AECOPD with PH was determined using the ROC curve. Results. A total of 83 patients were enrolled (56 in the AECOPD group and 27 in the AECOPD + PH group). The level of FeNO was significantly lower in the AECOPD + PH group than in the AECOPD group ( P = 0.022 ). Moreover, FeNO level (25.22 ± 8.45 ppb) was higher in the mild PH subgroup than in the moderate (16.64 ± 5.67 ppb, P = 0.005 ) or severe (11.75 ± 2.36, P = 0.002 ) PH subgroups. FeNO level was positively correlated with C-reactive protein in AECOPD patients while negatively correlated with brain natriuretic peptide in the AECOPD + PH group. ROC analysis showed that the optimal cutoff value of FeNO in the diagnosis of AECOPD with PH was 24.5 ppb. Conclusion. FeNO level at admission can act as an indicator for PH diagnosis in AECOPD patients.
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Kherad, Omar, Pierre-Olivier Bridevaux, Laurent Kaiser, Jean-Paul Janssens, and Olivier T. Rutschmann. "Is Acute Exacerbation of COPD (AECOPD) Related to Viral Infection Associated with Subsequent Mortality or Exacerbation Rate?" Open Respiratory Medicine Journal 8, no. 1 (April 4, 2014): 18–21. http://dx.doi.org/10.2174/1874306401408010018.

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Background: There is a growing interest in better defining risk factors associated with increased susceptibility to exacerbation in patients with COPD. Introduction: The aim of the study was to determine whether identification of a respiratory virus during a severe acute exacerbation of COPD (AECOPD) increases the risk of subsequent exacerbations and mortality during a one-year followup. Methods: Secondary analysis of 86 COPD patients admitted for AECOPD between June 2007 and December 2008 at Geneva’s University Hospital who were followed up for 1 year. Fifty-one percent of index AECOPD were related to viral infection. Rate of AECOPD, time to next AECOPD, and all-cause mortality were compared between patients with vs without viral index AECOPD. Results: Eighty-one cases were included in this secondary follow-up analysis. Mean exacerbation rate was 1.9 AECOPD per person-year for patients with viral index AECOPD vs 4.0 AECOPD per person year for those with non-viral index AECOPD. Incidence rate ratio (IRR) for subsequent AECOPD during one year follow up was lower for patients with viral index AECOPD (IRR 0.57; [CI 95% 0.39-0.84]), after controlling for previous exacerbations, and was strongly associated with the number of exacerbations in the year preceding the index AECOPD. During the one-year follow-up period, 16 patients (19%) died. In a Cox regression model, patients with a proven viral infection did not have a higher mortality (HR 0.56 [CI 95% 0.20 -1.58]). Conclusion: Viral AECOPD was not associated with a higher rate of subsequent exacerbations or mortality during the following year.
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Sarc, Irena, Alesa Lotric Dolinar, Tina Morgan, Joze Sambt, Kristina Ziherl, Dalibor Gavric, Julij Selb, Ales Rozman, and Petra Dosenovic Bonca. "Mortality, seasonal variation, and susceptibility to acute exacerbation of COPD in the pandemic year: a nationwide population study." Therapeutic Advances in Respiratory Disease 16 (January 2022): 175346662210810. http://dx.doi.org/10.1177/17534666221081047.

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Background: Previous studies have suggested that the coronavirus disease 2019 (COVID-19) pandemic was associated with a decreased rate of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Data on how the COVID-19 pandemic has influenced mortality, seasonality of, and susceptibility to AECOPD in the chronic obstructive pulmonary disease (COPD) population is scarce. Methods: We conducted a national population-based retrospective study using data from the Health Insurance Institute of Slovenia from 2015 to February 2021, with 2015–2019 as the reference. We extracted patient and healthcare data for AECOPD, dividing AECOPD into severe, resulting in hospitalisation, and moderate, requiring outpatient care. The national COPD population was generated based on dispensed prescriptions of inhalation therapies, and moderate AECOPD events were analysed based on dispensed AECOPD medications. We extracted data on all-cause and non-COVID mortality. Results: The numbers of severe and moderate AECOPD were reduced by 48% and 34%, respectively, in 2020. In the pandemic year, the seasonality of AECOPD was reversed, with a 1.5-fold higher number of severe AECOPD in summer compared to winter. The proportion of frequent exacerbators (⩾2 AECOPD hospitalisations per year) was reduced by 9% in 2020, with a 30% reduction in repeated severe AECOPD in frequent exacerbators and a 34% reduction in persistent frequent exacerbators (⩾2 AECOPD hospitalisations per year for 2 consecutive years) from 2019. The risk of two or more moderate AECOPD decreased by 43% in 2020. In the multivariate model, pandemic year follow-up was the only independent factor associated with a decreased risk for severe AECOPD (hazard ratio [HR]: 0.71; 95% confidence interval [CI]: 0.61–0.84; p < 0.0001). In 2020, non-COVID mortality decreased (−15%) and no excessive mortality was observed in the COPD population. Conclusion: In the pandemic year, we found decreased susceptibility to AECOPD across severity spectrum of COPD, reversed seasonal distribution of severe AECOPD and decreased non-COVID mortality in the COPD population.
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Mou, Shan, Wei Zhang, Yan Deng, Zhijun Tang, and Depeng Jiang. "Comparison of CRP, Procalcitonin, Neutrophil Counts, Eosinophil Counts, sTREM-1, and OPN between Pneumonic and Nonpneumonic Exacerbations in COPD Patients." Canadian Respiratory Journal 2022 (March 31, 2022): 1–9. http://dx.doi.org/10.1155/2022/7609083.

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Introduction. The patients with community-acquired pneumonia (CAP) and acute exacerbations of COPD (AECOPD) could have a higher risk of acute and severe respiratory illness than those without CAP in AECOPD. Consequently, early identification of pneumonia in AECOPD is quite important. Methods. 52 subjects with AECOPD + CAP and 93 subjects with AECOPD from two clinical centers were enrolled in this prospective observational study. The values of osteopontin (OPN), soluble triggering receptor expressed on myeloid cells-1 (sTREM-1), C-reactive protein (CRP), procalcitonin (PCT), eosinophil (EOS) counts, and neutrophil (Neu) counts in blood on the first day of admission and clinical symptoms were compared in AECOPD and AECOPD + CAP. In addition, subgroup analyses of biomarker difference were conducted based on the current use of inhaled glucocorticoids (ICS) or systemic corticosteroids (SCS). Results. Patients with AECOPD + CAP had increased sputum volume, sputum purulence, diabetes mellitus, and longer hospital stays than AECOPD patients ( p < 0.05 ). A clinical logistic regression model showed among the common clinical symptoms, purulent sputum can independently predict pneumonia in AECOPD patients after adjusting for a history of diabetes. At day 1, AECOPD + CAP patients had higher values of Neu, CRP, PCT, and OPN, while serum sTREM-1 levels and EOS counts were similar in the two groups. CRP fared best at predicting AECOPD with CAP ( p < 0.05 for the test of difference), while OPN had similar accuracy with Neu, PCT, and purulent sputum ( p > 0.05 for the test of difference). Multivariate analysis, including clinical symptoms and biomarkers, suggested that CRP ≥15.8 mg/dL at day 1 was a only promising predictor of pneumonia in AECOPD. CRP and OPN were not affected by ICS or SCS. Conclusions. CRP ≥15.8 mg/dL is an ideal promising predictor of pneumonia in AECOPD, and its plasma level is not affected by ICS or SCS. The diagnostic performance of CRP is not significantly improved when combined with clinical symptoms or other markers (OPN, PCT, and Neu).
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Dissertations / Theses on the topic "AECOPD"

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Flaherty, Helen M. "Informal Caregivers’ Experience During Acute Exacerbation of COPD in Older Adults: A Dissertation." eScholarship@UMMS, 2017. https://escholarship.umassmed.edu/gsn_diss/51.

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Chronic obstructive pulmonary disease (COPD) has been recognized as a leading cause of mortality in older adults involving acute exacerbations as life-threatening events that lead to frequent hospitalization for care. Informal caregivers have been essential to helping older adults with COPD during an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). A lack of empirical knowledge exists regarding the experience of informal caregivers of older adults with AECOPD in situation awareness for recognizing, understanding, and responding to an AECOPD in an emergent situation. This qualitative descriptive study explored situation awareness and its components of perception, comprehension and projection of next steps, including the caregiver’s confidence level during the AECOPD event. Fifteen informal caregivers, ages 31-77 years (mean age 48), who provided care for older adults with COPD were interviewed from an underserved community health center. The overarching theme derived from this study was something was wrong and something needed to be done. Subthemes emerged as a heightened sense of awareness, caregiver tipping point, planning next steps, caregiver confidence, and caregiver commitment. This study utilized situation awareness theory as a relevant guiding framework in exploring the experience of lay informal caregivers caring for older adults with AECOPD events. Study findings provided a description of the complex processes involved, including confidence level, for informal caregiver’s in situation awareness to recognize and respond to an AECOPD event in the older adult. Future targeted interventions need to address strategies to enhance individualized care for older adults with AECOPD events for managing care at home.
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GERMINI, FEDERICO. "COPD EXACERBATIONS IN THE EMERGENCY DEPARTMENT: EPIDEMIOLOGY, RELATED COSTS, AND VALIDATION OF THE RISK ASSESSMENT MODEL BAP-65." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/699516.

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Sintesi in lingua italiana – Parte prima Nei pazienti con BPCO, le riacutizzazioni sono una frequente causa di accesso in pronto soccorso e possono condizionarne negativamente la prognosi. Obiettivi dello studio erano: 1) descrivere le caratteristiche socio-demografiche e cliniche, nonché la gestione in pronto soccorso dei pazienti con riacutizzazione di bronco-pneumopatia ostruttiva cronica (BPCO); 2) stimarne i costi. Abbiamo condotto uno studio di coorte retrospettivo in Italia, raccogliendo dati su 4,396 pazienti da 34 centri. I pazienti avevano un’età media (deviazione standard [DS]) di 77 (11) anni, ed erano femmine nel 39% dei casi. Oltre il 70% dei pazienti presentava un indice di comorbidità moderato o severo, e nel 26% dei casi era presenta anche una diagnosi di scompenso cardiaco. Il 65% dei pazienti è stato ospedalizzato, per una durata media (DS) di 11 (10) giorni. Il costo stimato per paziente è 2.617 €. In conclusione, I pazienti che afferiscono in pronto soccorso con una riacutizzazione di BPCO sono anziani e gravate da importanti comorbidità. Il tasso di ricovero in questi pazienti è alto, e i costi onerosi. Sintesi in lingua italiana – Parte seconda Le riacutizzazioni di BPCO esitano frequentemente in ospedalizzazione, possono richiedere il trattamento con ventilazione invasiva e sono associate a elevata mortalità intraospedaliera. Il BAP-65 è modello di predizione del rischio di eventi avversi per pazienti con riacutizzazione di BPCO. Il BAP-65 è semplice da utilizzare e, se la sua accuratezza prognostica fosse confermata, potrebbe essere utilizzato per guidare la gestione dei pazienti. Abbiamo condotto uno studio retrospettivo, multicentrico in pazienti che afferivano in pronto soccorso per una riacutizzazione di BPCO durante il 2014. Lo scopo dello studio era validare il modello BAP-65 per la predizione dell’outcome combinato mortalità intraospedaliera e ricorso alla ventilazione invasiva. Abbiamo arruolato 2.908 pazienti da 20 centri Italiani. L’età media (DS) era 76 (11) anni, e il 38% dei pazienti era femmina. L’outcome combinato si è verificato nel 5% dei pazienti. L’area sotto la curva (AUROC) stimata per l’outcome combinato è risultata pari a 0,64 (95%CI 0,59-0,68). Un punteggio BAP-65 ≥ 4 ha mostrato una sensibilità pari a 44% (95% CI 34%-55%) nel predire la mortalità intraospedaliera, con specificità 84% (95% CI 82%-85%), valore predittivo positivo 9% (95% CI 6%-12%) e valore predittivo negativo 98% (95% CI 97%-98%). In conclusione, il modello BAP-65 non ha dimostrato accuratezza sufficiente per un’efficacie stratificazione del rischio di prognosi infausta nella popolazione studiata. DOI del primo articolo: https://doi.org/10.1016/j.ejim.2018.01.010 DOI del secondo articolo: https://doi.org/10.1016/j.ejim.2018.10.018.
Abstract part 1 Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) frequently cause patients with COPD to access the emergency department and have a negative impact on the course of the disease. The objectives of our study were: 1) describing the socio-demographic and clinical characteristics, and the clinical management, of patients with AECOPD, when they present to the emergency department; and 2) estimating the costs related to the management of these patients. We conducted a retrospective cohort study in Italy, collecting data on 4,396 patients, from 34 centres. Patients had a mean (SD) age of 76,6 (10.6) years, and 61.2 % of them where males. More than 70 % of the patients had a moderate to very high comorbidity burden, and heart failure was present in 26.4 % of the cohort. The 64.6 % of patients were admitted to hospital wards, with a mean (SD) length of stay of 10.8 (9.8) days. The estimated cost per patient was 2617 €. Conclusions: Patients attending the ED for an AECOPD are old and present important comorbidities. The rate of admission is high, and costs are remarkable. Abstract part 2 Exacerbations of chronic obstructive pulmonary disease (AECOPD) frequently require hospitalizations, may necessitate of invasive mechanical ventilation (IMV), and are associated with a remarkable in-hospital mortality. The BAP-65 score is a risk assessment model (RAM) based on simple variables, that has been proposed for the prediction of these adverse outcomes in patients with AECOPD. If showed to be accurate, the BAP-65 RAM might be used to guide the patients management, in terms of destination and treatment. We conducted a retrospective, multicentre, chart-review study, on patients attending the ED for an AECOPD during 2014. The aim of the study was the validation of the BAP-65 RAM for the prediction of in-hospital death or use of IMV (composite primary outcome). We assessed the discrimination and the prognostic performance of the BAP-65 RAM. We enrolled 2908 patients from 20 centres across Italy. The mean (standard deviation) age was 76 (11) years, and 38% of patients were female. The composite outcome occurred in 5.3% of patients. The AUROC of BAP-65 for the composite outcome was 0.64 (95%CI 0.59-0.68). The sensitivity of BAP-65 score ≥ 4 to predict in-hospital mortality was 44% (95% CI 34%-55%), the specificity was 84% (95% CI 82%-85%), the positive predictive value was 9% (95% CI 6%-12%), and the negative predictive value was 98% (95% CI 97%-98%). Conclusions: In patients attending Italian EDs with an AECOPD, we found that the BAP-65 score did not have sufficient accuracy to stratify patients upon their risk of severe in-hospital outcomes. DOI of published article # 1: https://doi.org/10.1016/j.ejim.2018.01.010 DOI of published article # 2: https://doi.org/10.1016/j.ejim.2018.10.018.
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COSTA, JULIANA SOARES MOURA. "CULTURAL TYPOLOGIES AND ORGANIZAT IONAL LI FE CYCLE: CASE ENSR / AECOM." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2008. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=11637@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO
Esta dissertação analisa o gerenciamento cultural ao longo do ciclo de vida de uma organização. Para tanto, foi feito um estudo de caso da ENSR Brasil - ENSR International Brasil Ltda., empresa do mercado de consultoria ambiental, presente no Brasil desde 1998. Com base em uma análise qualitativa, neste trabalho foi avaliada a evolução da cultura organizacional da ENSR Brasil em seus diferentes estágios evolutivos e, com base em modelos e tipologias culturais identificados na literatura, analisado o processo de mudança cultural instituído na empresa a partir de 2006, depois de instituída influência mais direta e efetiva da matriz americana. O resultado deste estudo reforça a literatura sobre o tema referente à questão da forte correlação entre cultura e ciclo de vida, evidenciando a importância de variáveis como a estrutura de poder e o processo decisório no gerenciamento da mudança organizacional.
This essay analyses the cultural management along the organization life cycle. With this purpose, a case study was developed based on the research of the company ENSR Brasil - ENSR International Brasil Ltda., which was established in Brazil in 1998. Based on a qualitative analysis, this works evaluates the evolution of ENSR Brasil`s organizational cultural in its different evolution stages. Additionally, by applying models and typologies identified in the literature, it analyses the process of cultural change established in the company from 2006 on, after a more direct and effective influence of the American head office was instituted. The result of this study reinforces the literature about the subject related to the strong correlation between culture and life cycle, pointing out the importance of variables such as power structure and the decision process in the management of the organizational change.
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Postigo, Ivan. "Fingerprinting methods for positioning: A study on the adaptive enhanced cell identity method." Thesis, Linköpings universitet, Kommunikations- och transportsystem, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-153314.

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Fingerprinting methods for positioning is an area of great interest, this thesis presents a study on the Adaptive Enhanced Cell Identity (AECID) fingerprinting method for positioning. By creating a map of the radio characteristics in a geographical region, the AECID method is able to locate a UE by gathering information of the radio conditions of its current location. By performing positioning in this manner, there is no need for additional signaling, which is a better usage of the radio resources. This thesis presents a new approach for the creation of fingerprints together with alternative methodology at each step proposed by the AECID method. These alternatives are implemented and evaluated for real and simulated scenarios. Accuracy performance metrics are discussed based on different formats supported for reporting position. The alternatives presented in this thesis will show not only an enhancement on the accuracy levels but most importantly, the impact of each step on the final performance of the method.
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Winnubst, Patrick. "REPORT OF AN INTERNSHIP WITH ENSR|AECOM INC. SEPTEMBER 2006 TO SEPTEMBER 2007." Miami University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=miami1229032333.

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Шаламов, Станислав Павлович. "Методология определения требований к открытой и закрытой испытательной площадке согласно процедуре NRS03 стандарта STANAG 4370 AECTP 500." Thesis, Национальный технический университет "Харьковский политехнический институт", 2017. http://repository.kpi.kharkov.ua/handle/KhPI-Press/43951.

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Miquet, Harald. "Collectivités territoriales et systèmes de régulation en matière de communications électroniques." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0227.

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La reconnaissance progressive aux collectivités territoriales de compétences spécifiques en matière de création et gestion de réseaux et services de communications électroniques évolue dans une double perspective.Prises dans leur rôle d'aménageur du territoire, les collectivités territoriales ont en charge la coordination d'activités en réseau qui peuvent revêtir la forme d'un service public local. Cette étude s'enrichit à la faveur de l'analyse des modalités de coopération entre les initiatives publiques et privées qui semblent être inspirées par une logique de subsidiarité fonctionnelle. Opérateurs économiques soumis aux règles de concurrence, les collectivités territoriales accèdent également au statut d'opérateur de communications électroniques, astreint à la régulation spécifique d'un secteur libéralisé. L'objet de la recherche vise in fine à esquisser la morphologie de l'initiative publique locale à la lumière des principaux modèles de régulationà l'oeuvre dans le cadre du développement des réseaux de nouvelle génération
Nowadays, more and more responsibility is being handed over to local authorities in the setting up and running of publicly-owned broadband networks. The way in which this growing responsibility is implemented has to be studied from the dual aspect of public and private intervention.For although, as planners of local development, local authorities are responsible for the coordination of public service broadband activities, they nevertheless call upon the expertise of private enterprise. This thesis analyses how cooperation between public and private sectors works and seems to be driven by a logic of functional subsidiarity. Local authorities, as economic operators subject to the competition rules of the Treaty, now acquire the status of telecommunications service provider and are thus governed by specificliberalised sector regulations. The purpose of the present work is to outline how public intiatives are shaped by the main regulatory models to which the deployment of next generation access networks is subject
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Makinen, Timo Allan. "The predictive accuracy of over-the-counter natural gas price projections, a comparison of the AECO and Sumas pricing hubs." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0010/MQ61463.pdf.

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Retamal, Cisterna Silvia. "Análisis de las condiciones de éxito de un programa de desarrollo educativo. Proyecto: apoyo y fortalecimiento educacional en gestión directiva y competencias profesionales docentes. Proyecto: AECID coyhaique-Chile." Doctoral thesis, Universitat Autònoma de Barcelona, 2012. http://hdl.handle.net/10803/96711.

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La presente tesis doctoral consiste en el análisis de las condiciones de éxito de un programa de desarrollo educativo, centrada principalmente en los factores que determinan el cambio en los centros educativos y en el grado que se dan esos procesos en las escuelas municipalizadas de la comuna de Coyhaique. El programa de desarrollo educativo mencionado, actualmente en su fase final, es llevado a cabo bajo la coordinación y apoyo de diversas instituciones, siendo las principales la Agencia Española de Cooperación internacional para el Desarrollo (AECID), la Universidad Autónoma de Barcelona y la Municipalidad de Coyhaique, Chile, cuya intervención se justifica en la necesidad de construir una red de cooperación y apoyo con y entre los establecimientos dependientes de la comuna de Coyhaique. El motivo de esta investigación es detectar si las escuelas de Coyhaique adscritas a este proyecto poseen las condiciones para que se dé el cambio, para eso fue necesario; a) determinar cuáles son las condiciones que influyen en el éxito de un programa de desarrollo educativo, mediante el diseño de un modelo de evaluación comprensiva que permitió conocer profundamente el contexto de actuación e identificar los principales elementos condicionantes del cambio; b) realizar una revisión de la literatura y de resultados de investigaciones respecto al cambio educativo para establecer cuáles son los condicionantes institucionales y territoriales que más aparecen y determinan los cambios en educación y por último; c) analizar en qué medida se dan esas condiciones a través de las experiencias de los mismos directivos y descubrir cuáles son los condicionantes para el cambio que caracterizan a las escuelas de la comuna de Coyhaique. El estudio realizado fue de tipo exploratorio centrado en el estudio teórico y práctico de cómo se abordan los procesos de mejora en la escuela, para así determinar con más precisión cuáles son los factores que inhiben y facilitan el cambio en determinados contextos educativos. Para poder intervenir en propuestas que fortalezcan las áreas más débiles y promover de mejor manera los cambios educativos, estableciendo criterios, pautas y procedimientos ajustados a la realidad de los centros educativos y a los programas de mejoramiento que en ella se desarrollen. De los hallazgos resultantes de esta investigación se concluye que existen factores que favorecen e inhiben los procesos de cambio en la escuela. Las escuelas son conscientes en la teoría de las condiciones que ayudan a su desarrollo. Pero en la práctica existen limitaciones que hacen que la mejora no se lleve a cabo. Éstas limitaciones se reconocen en diferentes aspectos o ámbitos del que hacer educativo, en el que visualizamos; el tema de las competencias y limitaciones profesionales de los que trabajan en las escuelas; las estructuras educativas políticas y administrativas; el contexto familiar del estudiante; el lugar geográfico y el desarrollo regional, pero por sobre todo, se destaca el desconocimiento del potencial que poseen las escuelas y sus actores para dinamizar un cambio en su propia unidad educativa.
In this PhD thesis, an analysis of success conditions of an educational improvement program was performed. This study was focused in factors determining change in schools and how are shown them in public schools at Coyhaique, Chile. This study was supported in framework of project “Apoyo y Fortalecimiento Educacional en gestion Directiva y Competencias Profesionales Docentes” in collaboration with Agencia Española de Cooperacion Internacional para el Desarrollo, Universidad Autónoma de Barcelona and Municipalidad de Coyhaique. The main goal of this study was detected if change conditions in Coyhaique schools can be feasible. In this way was necessary a) to determine conditions that can influence the success of an educational program, by designing a comprehensive evaluation model. This model have allowed to know the study context and identify the main change conditions; b) to carry out a bibliographic study to establish institutional and territorial conditions, which can determine changes in the education and c)to analyse qualitatively change conditions through the experiencies of principals. In order to better conduce change processes, a theoretical and practical study was performed. In order to better promote educational changes, factors that inhibit and facilitate changes in specific educational contexts were determined. The methodology includes guidelines and procedures adjusted to the reality of schools and improvement programs. The main results have allowed recognize factors that favor and inhibit change processes in the school. Schools are aware in the theory of the conditions that help your development. But in practice there are limitations that avoid the improvement. These limitations are recognized in different aspects or areas of education. Some limitations are competences and professional deficiencies of teachers, the educational policies and administrative structures, the student's family background, geographic location and regional development. But is very important highlight the participation of entire school in the dynamization of the educational change.
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Zuloeta, Ascoy Katherin Tatiana. "Implementación de la solución tecnológica AECOM para mejorar la comunicación entre los agentes de la educación del nivel primario de la Institución Educativa Cristiana Abrams School, octubre-diciembre 2011." Thesis, Universidad Católica Santo Toribio de Mogrovejo, 2011. http://tesis.usat.edu.pe/jspui/handle/123456789/65.

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La presente investigación denominada fue una alternativa que surgió con la finalidad de superar la deficiencia que existe en la comunicación entre los padres de familia y la escuela. Los resultados refieren a un estudio cualitativo, y de tipo cuasiexperimental, que consto de un pre-test y un pos-test. La solución tecnológica AECOM, propuso la implantación de un entorno web como canal de comunicación, en dónde se brindó información académica del alumno (notas por unidad y bimestrales, resumen asistencias, reportes conductuales); también permitió la realización de consultas y la emisión de comunicados por parte del docente y el padre de familia respectivamente. Tras la implementación de la propuesta incrementó en un 22% la participación de los padres de familia en las reuniones, llegando a ser los asistentes a estas un 64% del total de la población. Así como también se pudo constatar el incrementó de un 20% del nivel de percepción sobre la calidad de la comunicación entre los agentes de la educación, evidencia de esto es que un 61% de padres de familia calificaron como muy buena a la comunicación que se dio entre ellos y la institución.
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Books on the topic "AECOPD"

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The bigger picture. London: Black Dog, 2009.

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Daouas, Thouraya. La formation virtuelle pour l'apprentissage continu et l'échange culturel en Mediterranée: Conclusion du Projet AECID. Tunis: I.H.E Editions, 2014.

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García, Santiago Molina. Educación especial: Inclusión socioeducativa y discapacidad : programa de cooperación interuniversitaria, financiado por la Agencia Espanola de Cooperacion Internacional (AECID). Santa Cruz de la Sierra, Bolivia: Grupo Editorial La Hoguera, 2012.

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Martín, Araceli García. La ilustración hispánica: Mestiza y universal : catálogo de la exposición celebrada en la AECID (Madrid) de septiembre de 2017 a febrero de 2018. Madrid: AECID, 2018.

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Ch, Forceville, Land Hillig van t', and Stichting Studiegenootschap Canada, eds. European perspectives on English-Canadian literature: Annual Canadian studies seminar ACSN/AECP-B, Vrije Universiteit Amsterdam, The Netherlands, 1995. Nijmegen: Stichting Studiegenootschap Canada", 1995.

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Conocer para transformar: Producción y reflexión sobre ciencia, tecnología e innovación en Iberoamérica : IV Encuentro de Jóvenes Investigadores y 1ra Escuela Doctoral Iberoamericana en Estudios Sociales y Políticos sobre la Ciencia y la Tecnología--ESOCITE/CYTED/AECID/IVIC/UNESCO-IESALC. Caracas: UNESCO, IESALC, 2010.

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Macagno, Francesco, and Massimo Antonelli. Therapeutic strategy in acute or chronic airflow limitation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0112.

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The fragility of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) accounts for their frequent hospitalization and their high intensive care unit risk. Therapy for AECOPD is varied and the need for hospitalization must be always carefully evaluated, considering the risk factors related to the presence of multi-resistant pathogens or the need of invasive procedures. The prolonged use of oxygen therapy requires an accurate monitoring of blood gases and continuous oximetry. Inhalation therapy can be performed using nebulizers, predosed aerosols or powders for inhalation. Corticosteroids for oral and systemic use now play an established role in AECOPD, because bacterial infections account for 50% of exacerbations. Non-invasive ventilation (NIV) must be considered the first option in AECOPD patients and acute respiratory failure if there are no contraindications. The careful monitoring of the patient and the response to NIV are indispensable elements for therapeutic success.
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Saefurrohman, Malim Muhammad, and Heri Nurdiyanto. Proceedings of the 6th Asia-Pacific Education and Science Conference, AECon 2020, 19-20 December 2020, Purwokerto, Indonesia: AECon 2020. EAI Publishing, 2020.

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Reitz, Kevin R. American Exceptionalism in Crime and Punishment: Broadly Defined. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190203542.003.0001.

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This introductory chapter is a primer on American exceptionalism in crime and punishment (AECP). In the mid- and late twentieth century, the United States diverged markedly from other Western nations first in its high rates of serious violent crime and soon after in the severity of its governmental responses. This has left an appalling legacy of AECP for the new century. The chapter expands on the scholarship in this field first by providing a brief tour of well-known AECP subject areas: incarceration and the death penalty. Next, it introduces claims that a wider menu of punishments should be included in AECP analyses, including probation supervision, parole release and supervision, economic penalties, and collateral consequences of conviction. To conclude, the chapter speaks to the importance of late twentieth-century crime rates to US punitive expansionism.
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Admixtures - Enhancing Concrete Performance. Thomas Telford Ltd, 2005. http://dx.doi.org/10.1680/aecp.34075.

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Book chapters on the topic "AECOPD"

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Larsen, Reinhard, and Thomas Ziegenfuß. "Akute respiratorische Insuffizienz bei chronisch- obstruktiver Lungenerkrankung (AECOPD)." In Beatmung, 461–79. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-54853-0_26.

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Lichtenstein, Daniel A. "BLUE-Protocol and Bronchial Diseases: Acute Exacerbation of COPD (AECOPD) and Severe Asthma." In Lung Ultrasound in the Critically Ill, 187–88. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-15371-1_25.

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Bonduel, Mathias, Pieter Pauwels, and Ralf Klein. "Property modelling in the AECO industry." In Buildings and Semantics, 25–50. London: CRC Press, 2022. http://dx.doi.org/10.1201/9781003204381-3.

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Skopik, Florian, Markus Wurzenberger, and Max Landauer. "AECID: A Light-Weight Log Analysis Approach for Online Anomaly Detection." In Smart Log Data Analytics, 99–129. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74450-2_6.

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Eistert, Torsten. "Case “AECOM EDI” — The EDI Project for the Spanish Retail Industry." In EDI Adoption and Diffusion, 197–241. Wiesbaden: Deutscher Universitätsverlag, 1996. http://dx.doi.org/10.1007/978-3-663-08436-5_6.

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Kosicki, Marcin, Marios Tsiliakos, Khaled ElAshry, Oscar Borgstrom, Anders Rod, Sherif Tarabishy, Chau Nguyen, Adam Davis, and Martha Tsigkari. "Towards DesignOps Design Development, Delivery and Operations for the AECO Industry." In Towards Radical Regeneration, 61–70. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-13249-0_6.

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Zhen, Yu, Clyde Zhengdao Li, Zhenchao Guo, Shanyang Li, Meiqin Xiong, and Limei Zhang. "‘Engineering Brain’ of the AECO Industry: A Safety Management System for the Life Cycle of Prefabricated Buildings Based on ‘BIM +’." In Lecture Notes in Operations Research, 14–25. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-5256-2_2.

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Özturk, Gözde Basak. "The Integration of Building Information Modeling (BIM) and Immersive Technologies (ImTech) for Digital Twin Implementation in the AECO/FM Industry." In BIM-enabled Cognitive Computing for Smart Built Environment, 95–129. First edition. | Boca Raton, FL : CRC Press, 2021.: CRC Press, 2021. http://dx.doi.org/10.1201/9781003017547-5.

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Greco, Nicola. "Akut exazerbierte COPD (AECOPD)." In Leitfaden Geriatrie Physiotherapie, 112–13. Elsevier, 2020. http://dx.doi.org/10.1016/b978-3-437-45381-6.00010-4.

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Chatreewatanakul, Buntarika. "Early Warning Signs and Prodromal Symptoms of AECOPD Patients." In Chronic Obstructive Pulmonary Disease - A Compendium of Medicine and the Humanities [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.107054.

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An acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a major problem leading to the most cause of death in chronic obstructive pulmonary disease (COPD) patients. Most cases of AECOPD occurred at home and outside the hospital. The COPD patients have the pattern of AECOPD according to their individual experiences. When the patients had AECOPD, also the warning signs and prodromal symptoms were happened differently. However, the characteristics of warning signs and prodromal symptoms could be described in three categories: 1) early signs and symptoms, 2) signs and symptoms that make the patients worse, and 3) time of occurrence. If the patients have been ill with COPD for a period of time until they can learn his/her early warning signs and prodromal symptoms of AECOPD by themselves or/and with their caregivers or/and with healthcare professionals, they will be able to quickly recognize their signs and symptoms when they occur and will be able to manage them as soon as according to their competency individually.
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Conference papers on the topic "AECOPD"

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Ohar, Jill, Chee Loh, Tina Lovings, Sharon Cornelison, and James Donohue. "RT protocol reduces AECOPD readmissions." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa551.

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Joveš-Sević, Biljana, Dušanka Obradović, Ivana Stojkovic, and Jelena Repic. "Early predictors of NIV failure in AECOPD." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa1880.

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Remakus, CB, F. Cordova, D. Ciccolella, CL Grabianowski, J. Gaughan, and GJ Criner. "Efficacy of Corticosteroids and Antibiotics in AECOPD." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5356.

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Naik, S., R. Ragatha, H. Campbell, and M. Anwar. "P33 Effect of Covid19 on AECOPD admissions." In British Thoracic Society Winter Meeting, Wednesday 17 to Friday 19 February 2021, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2021. http://dx.doi.org/10.1136/thorax-2020-btsabstracts.178.

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Drivas, George, Georgios Hillas, Anastasia Papaporfyriou, Maria Kaponi, and Katerina Dimakou. "PROMS and FEV1 as predictors of AECOPD." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1002.

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Naik, Samir, Ravi Ragatha, Mohammad Anwar, and James Seigel. "Utility of predischarge spirometry in AECOPD discharges." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa2512.

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Lopez Lopez, Laura, Marie Carmen Valenza, Irene Torres Sanchez, Irene Cabrera Martos, Mª Paz Moreno Ramirez, and Araceli Ortiz Rubio. "Results between two electrostimulation modalities in AECOPD patients." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2562.

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Araújo Oliveira, Ana Luisa, Carla Valente, and Alda Marques. "Measurement properties of muscle strength tests in AECOPD." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa4706.

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Valenza, Marie Carmen, Irene Torres-Sanchez, Concepcion Morales-Garcia, Paz Moreno, Janet Rodriguez, and Araceli Ortiz. "Effectiveness of an occupational therapy program after AECOPD." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa3057.

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Treat, S., I. Biney, J. Ferris, R. Heidel, P. Terry, and R. Dhand. "Comparing Discharge and Readmission Medication Regimen for AECOPD." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2258.

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Reports on the topic "AECOPD"

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Ma, He, Jifu Zhao, and Zhilei Wang. Efficacy and safety of HuaYu TongFu Method combined with acupuncture in the treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease:A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0114.

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Review question / Objective: This study is the protocol for a systematic review to evaluate the efficacy and safety of HuaYu TongFu Method combined with acupuncture in the treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease. we conducted a systematic review and meta-analysis of published randomized clinical trials (RCTs) of such combined therapy in the treatment of AECOPD, It provides a reliable scientific basis for clinicians to use this approach to treat AECOPD. Condition being studied: Chronic obstructive pulmonary disease is the third leading cause of death worldwide. AECOPD is the most common cause of hospitalization and death in patients with COPD. As lung function deteriorates and the disease progresses, the risk of alveolar hypoxia and consequent hypoxemia increases. Inflammation plays an important role in the progression of AECOPD. Modern medicine mainly treats AECPD by anti-inflammatory, relief of airway spasm, glucocorticoids, inhalants and other methods. Long-term application can easily lead to bacterial flora imbalance and drug resistance in patients. Comparatively, traditional Chinese medicine and acupuncture therapy are safe and effective.To assess the therapeutic efficacy and safety of HuaYu TongFu Method combined with acupuncture in AECOPD, we created a protocol for a systematic review to inform future clinical applications.
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Xing, Lei, Hongmin Guo, and Zhiqian Wang. Efficacy and safety of Suzi Jiangqi Decoction in patients with acute exacerbation of chronic obstructive pulmonary disease A protocol for systematic review and meta analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2021. http://dx.doi.org/10.37766/inplasy2021.8.0035.

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Background: Chronic obstructive pulmonary disease (COPD) is characterized by chronic respiratory symptoms. The respiratory symptoms of patients with acute exacerbation of COPD (AECOPD) worsen rapidly. At present, traditional western medicine treatment can not effectively alleviate the symptoms and attack frequency of patients. Suzi Jiangqi decoction(SZJQ) has a good clinical effect in the treatment of AECOPD. Due to the lack of evidence-based medicine, it can not provide an effective systematic evaluation for the treatment of AECOPD with Suzi Jiangqi decoction. Therefore, it is necessary to provide high-quality evidence evaluation for the clinical efficacy and safety of Suzi Jiangqi Decoction in the treatment of AECOPD. Methods: Two researchers independently retrieved randomized controlled trial (RCT) and quasi-RCTs of SZJQ in the treatment of AECOPD from databases including PubMed, Web of science, the Cochrane Library, CBM, CNKI, Sinomed, VIP and WanFang.The included studies were evaluated for quality according to the RCT quality assessment method provided by Cochrane Reviewer's Handbook 5.3.Review Manager 5.3 software provided by the Cochrane collaboration was used for meta-analysis. Results: This study will provide systematic review on the efficacy and safety of SZJQ as adjuvant therapy in patients with AECOPD by rigorous quality assessment and reasonable data synthesis. Conclusions: This systematic review will provide the good evidence currently on SZJQ as adjuvant therapy in patients with AECOPD.
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Baker, Christine Ruth. LANL 851 Amendment Gap Analysis - AECOM. Office of Scientific and Technical Information (OSTI), August 2018. http://dx.doi.org/10.2172/1463592.

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Ibáñez, Ana María, Juliana Quigua, Jimena Romero, and Andrea Velásquez. Responses to Temperature Shocks: Labor Markets and Migration Decisions in El Salvador. Inter-American Development Bank, May 2022. http://dx.doi.org/10.18235/0004237.

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Abstract:
By 2017, one-quarter of people born in El Salvador were estimated to be living in the U.S. We show that extreme temperatures have negatively aected agricultural production and increased international migration from El Salvador. We nd that labor markets act as a transmission mechanism of the negative eects of weather shocks on agricultural workers, who react by migrating internationally or reallocating within local labor markets. However, these responses dier by landownership status and access to risk-coping mechanisms. Our results suggest that, despite the current anti-immigrant political climate, there should be a global responsibility relative to the consequences of climate change.
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