Academic literature on the topic 'Adverse pregnancy outcomes'

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Journal articles on the topic "Adverse pregnancy outcomes"

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Mhaske, Maya, Mithila Kakade, Sushma Belkhede, and Kalyani Reddy. "Periodontal Disease and Adverse Pregnancy Outcomes." International Journal of Science and Research (IJSR) 10, no. 6 (June 27, 2021): 213–17. https://doi.org/10.21275/sr21531150558.

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Metzger, B. E., L. P. Lowe, A. R. Dyer, E. R. Trimble, U. Chaovarindr, D. R. Coustan, D. R. Hadden, et al. "Hyperglycemia and Adverse Pregnancy Outcomes." Obstetric Anesthesia Digest 29, no. 1 (March 2009): 39–40. http://dx.doi.org/10.1097/01.aoa.0000344706.95925.dc.

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Metzger, Boyd E., Donald R. Coustan, and Elisabeth R. Trimble. "Hyperglycemia and Adverse Pregnancy Outcomes." Clinical Chemistry 65, no. 7 (July 1, 2019): 937–38. http://dx.doi.org/10.1373/clinchem.2019.303990.

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&NA;. "Hyperglycemia and Adverse Pregnancy Outcomes." Survey of Anesthesiology 53, no. 1 (February 2009): 18–19. http://dx.doi.org/10.1097/01.sa.0000318681.02582.c6.

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Jonsdottir, Sigridur Sia. "Hyperglycemia and Adverse Pregnancy Outcomes." MCN, The American Journal of Maternal/Child Nursing 34, no. 4 (July 2009): 266. http://dx.doi.org/10.1097/01.nmc.0000357930.30798.3d.

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Lynch, Anne, James Murphy, Ronald Gibbs, Patricia Giclas, Jane Salmon, and V. Michael Holers. "C3a and adverse pregnancy outcomes." Molecular Immunology 47, no. 13 (August 2010): 2199. http://dx.doi.org/10.1016/j.molimm.2010.05.017.

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Dungan, J. S. "Hyperglycemia and Adverse Pregnancy Outcomes." Yearbook of Obstetrics, Gynecology and Women's Health 2009 (January 2009): 55–56. http://dx.doi.org/10.1016/s1090-798x(09)79072-1.

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Heres, Marion, Adriaan Honig, and Hanneke Wennink. "SSRIs and adverse pregnancy outcomes." American Journal of Obstetrics and Gynecology 196, no. 1 (January 2007): e26. http://dx.doi.org/10.1016/j.ajog.2006.06.025.

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Goldstein, David J. "Adverse pregnancy outcomes with SSRIs." American Journal of Obstetrics and Gynecology 196, no. 1 (January 2007): e25. http://dx.doi.org/10.1016/j.ajog.2006.06.027.

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Ness, Roberta B. "Intersections between Adverse Pregnancy Outcomes." Women's Health 1, no. 2 (September 2005): 245–51. http://dx.doi.org/10.2217/17455057.1.2.245.

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Reproductive failure in a variety of forms, whether it be infertility, miscarriage, pre-eclampsia, prematurity or intrauterine growth restriction, may aggregate within individuals. This observation, although rarely studied, suggests that single pathophysiologies may be associated with a variety of reproductive morbidities. In this review, hyperimmune responsiveness to pregnancy is provided as one example of a process leading to a multitude of adverse impacts on healthy childbearing. Further research on reproductive failure as a spectrum is warranted.
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Dissertations / Theses on the topic "Adverse pregnancy outcomes"

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Shub, Alexis. "Periodontal disease and adverse pregnancy outcomes." University of Western Australia. School of Women's and Infants' Health, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0184.

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[Truncated abstract] Periodontal disease is a common and underdiagnosed disease in humans that may have adverse effects on pregnancy outcomes. The aim of this thesis was to investigate the effects of periodontal disease in pregnancy by means of two observational human studies and the development of animal models of fetal and uterine exposure to periodontopathic bacteria and lipopolysaccharide. I performed a prospective study examining the rates of preterm birth, small for gestational age neonates and neonatal inflammation in 277 women who had undergone a detailed antenatal periodontal examination and oral health questionnaire. Periodontal disease was associated with small for gestational age neonates, and increased CRP levels in umbilical cord blood, but no effect was seen on the rate of preterm birth. Maternal oral health symptoms predicted both periodontal disease and newborn biometry. In a retrospective case control study, I examined the role of periodontal disease in perinatal mortality. Participants included 53 women who had experienced a perinatal loss for which no cause could be found after thorough investigation, and 111 control women. Women who had experienced a perinatal loss were more than twice as likely as controls to have periodontal disease. The incidence of periodontal disease was even higher in women in whom the perinatal loss was due to extreme prematurity. In contrast to my prospective study, risks to the pregnancy could not be predicted by maternal oral health behaviours or oral health symptoms. In order to better understand the mechanisms regulating the associations described in the human studies, two animal models were developed; one to investigate acute exposure and the second to investigate long-term exposure to periodontal pathogens. The first study examined the effects of administration of a bolus of periodontopathic bacteria and lipopolysaccharide to the pregnant sheep. Injection of bacteria and lipopolysaccharide in the amniotic fluid of the pregnant preterm sheep caused a high rate of fetal lethality, disturbance of fetal acid base status and inflammation of the fetus and membranes. Given the circumstances of exposure to periodontopathic pathogens in human periodontal disease, a model investigating long-term exposure to periodontopathic lipopolysaccharide on pregnancy outcomes was developed. ... Overall, I have demonstrated that maternal periodontal disease is associated with adverse pregnancy outcomes including fetal growth restriction and possibly perinatal loss. Mechanisms regulating these effects are likely to be mediated by fetal adaptations to intrauterine inflammation resulting in altered fetal development, growth or survival. Randomised controlled trials that are currently in progress will provide further information on the effects of periodontal disease in human pregnancy, and the efficacy of treatment to reduce these adverse outcomes.
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Janssen, Patti Alice. "Domestic violence and adverse pregnancy outcomes /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/10912.

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Price, Tabitha. "Periodontal Disease and Adverse Pregnancy Outcomes: Treatment Recommendations for the Pregnant Patient." Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etsu-works/2530.

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Gaudet, Laura. "Macrosomia and Related Adverse Pregnancy Outcomes: The Role of Maternal Obesity." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/22802.

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Fetal overgrowth is associated with adverse outcomes for offspring and with maternal obesity. Results from a systematic review and meta-analysis showed that maternal obesity is associated with fetal overgrowth, defined as birthweight ≥4000g (OR 2.17, 95% CI 1.92, 2.45), birthweight ≥4500g (OR 2.77, 95% CI 2.22, 3.45) and birthweight ≥90%ile for gestational age (OR 2.42, 95% CI 2.16, 2.72). A retrospective cohort study revealed that mothers whose infants are macrosomic are more likely to require induction of labour (OR 1.42, 95% CI 1.10-1.98) and delivery by Cesarean section (OR 1.45, 95% CI 1.04-2.01), particularly for maternal indications (OR 3.7, 95% CI 1.47-9.34), if they are obese. Infants from these pregnancies are significantly more likely to require neonatal resuscitation in the form of free flow oxygen (OR 1.57, 95% CI 1.03, 2.42) than macrosomic infants of non-obese mothers. Thus, co-existing maternal obesity and macrosomia increases the risk of adverse pregnancy outcomes.
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Allen, Rebecca Emma. "Prediction and prevention of preeclampsia and other adverse pregnancy outcomes." Thesis, Queen Mary, University of London, 2018. http://qmro.qmul.ac.uk/xmlui/handle/123456789/33944.

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Aim To assess current methods of prediction of adverse pregnancy outcomes, develop a prediction model and assess diet and life style in preventing preeclampsia. Methods Meta-analyses performed to assess the role of abnormal 1st trimester biomarker levels in predicting PE and the predictive accuracy of 2nd trimester UAD indices for stillbirth. A prospective observational study was performed to assess the efficacy of maternal characteristics, biomarkers, arteriography and UADs for predicting adverse pregnancy outcomes. Previously published 1st trimester PE prediction models were validated using data collected from the observational study. A systematic review on the effect of diet and life style based metabolic risk modifying interventions on PE was performed. Results The review of biomarkers found that abnormal levels were particularIy associated with early onset PE. The stillbirth review demonstrated a three-four fold increased risk of still birth with abnormal UAD. 1045 women were included for analysis in the prospective observational study. Our models' detection rate (false positive rate of 15%) was 72% for PE; 48% PIH; 30 % SGA < 10th centile; 57% SGA < 5th centile and 67% stillbirth. In the validation study the observed discrimination ability in the derivation studies ranged from 0.70 to 0.954. When validated against the study cohort, the AUC varied importantly, ranging from 0.504 to 0.833. Dietary interventions were shown to reduce the risk of PE by 33%, with no reduction in risk with mixed interventions or fatty acid supplementation. Conclusion The high heterogeneity of studies in the systematic reviews makes it difficult to draw firm conclusions regarding the use of biomarkers or UADs in screening for pregnancy complications. Our prospective study showed a role for haemodynamics as part of routine 1st trimester screening for assessing the risk of hypertensive disease in pregnancy.
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Potdar, Neelam. "Maternal caffeine consumption and its relationship to adverse pregnancy outcomes." Thesis, University of Leicester, 2010. http://hdl.handle.net/2381/8325.

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There are conflicting reports about the association of maternal caffeine intake with adverse pregnancy outcomes, specifically fetal growth restriction (FGR). Differences in study design and exposure definition have been partly responsible. In order to study the association between maternal caffeine consumption and FGR, I prospectively quantified caffeine intake in pregnancy from all known sources, assessed caffeine metabolism in pregnancy and used serial ultrasound growth scans to identify FGR fetus. In a prospective study of 1340 pregnant women in Leicestershire, UK, I quantified total caffeine intake from 4-weeks prior and throughout pregnancy using a validated caffeine assessment tool. Caffeine half-life (used here as proxy for clearance) was determined by measuring caffeine in saliva after a caffeine challenge. The primary outcome measure was FGR, which was determined by customised birth weight centile calculator and in a subgroup by serial ultrasound growth scan. Mean caffeine consumption decreased in the 1st and then increased in the 3rd trimester. Caffeine consumption throughout pregnancy was associated with an increased risk of FGR: OR = 1.2 (95% CI, 0.9 to 1.6) for 100-199 mg/day, OR = 1.5 (1.1 to 2.1) for 200- 299 mg/day, and OR = 1.4 (1.0 to 2.0) for over 300 mg/day compared to < 100 mg/day (Ptrend< 0.001). There was some evidence that the effect of caffeine on FGR was strongest in women with faster caffeine clearance (P = 0.06). On comparing outcome measure of FGR as defined by serial ultrasound growth scans in pregnancy and customised centile calculator, there was a moderate degree of agreement between the two methods (κ = 0.38, CI 0.26, 0.49). Caffeine consumption during pregnancy is associated with an increased risk of FGR and this effect is continuous throughout pregnancy. This effect was observed from four weeks before pregnancy and was statistically significant in the first trimester. A public health recommendation for pregnant women would be to reduce or limit the caffeine intake to a maximum of 2 cups of tea/coffee per day. Future research is required to study the mechanistic effect of caffeine on trophoblastic tissue.
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Giakoumelou, Sevasti. "The role of Chlamydia trachomatis infection in adverse pregnancy outcomes." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/29574.

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Chlamydia trachomatis (Ct), the most common sexually transmitted bacterium, has been associated with adverse pregnancy outcomes including controversial data on miscarriage, intrauterine growth restriction and low birth weight, however the causative mechanisms are unknown. A successful pregnancy requires normal endometrial stromal cell (ESC) decidualisation and trophoblast invasion, processes that involve chemokine action and lead to successful implantation. My objectives were to determine whether Ct infection impacts upon ESC decidualisation and chemokine secretion on human primary ESC invitro, to investigate the role of Ct infection in pregnancy in-vivo using a murine model of pregnancy and to investigate the role of Ct in miscarriage in a statistically powered case control study. A novel finding is that Ct can infect and proliferate in ESC, resulting in suboptimal decidualisation as measured by decidualisation marker prolactin’s reduced mRNA and protein levels in infected ESC. Furthermore, the altered secreted chemokine profile of decidualised ESC suggests an attenuated innate immune response from infected ESC. Focusing on chemokines C-X-C motif chemokine 12 (CXCL12) and CXCL16, important for trophoblast invasion, decreased mRNA and protein concentrations were detected in infected decidualised cells. From the in-vivo mouse model of past Ct infection in pregnancy, it was demonstrated that Ct infection did neither affect the fertility of the mice, pregnancy or resorption numbers in C3H mice nor alter embryonic and placental weight on e12 embryos. However, Ct infection caused reduction of embryo and placenta weight on e14 embryos. Finally, preliminary data from the case control study indicate that past Ct infection is not associated with miscarriage. Our in house PGP3 ELISA that detects past Ct infection was more sensitive than a commercially available MOMP ELISA. My data suggests that Ct infection affects pregnancy during the implantation stage by impairing decidualisation and altering chemokine secretion predisposing for adverse pregnancy outcomes that include growth restriction during later gestation.
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Cheong-See, Fi. "Predictors for adverse maternal and fetal outcomes in high risk pregnancy." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/25811.

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This thesis aims to undertake health technology assessments in high risk pregnancies through the following objectives: 1. In women with pre-eclampsia, a) To evaluate the association of maternal genotype and severe pre-eclampsia b) To assess the accuracy of tests in predicting adverse pregnancy outcomes c) To develop composite outcomes for reporting in trials on late onset pre-eclampsia 2. In women with multiple pregnancy, a) To study the association between chorionicity and stillbirth b) To identify the optimal timing of delivery in monochorionic and dichorionic twin pregnancies 3. In the field of prediction research in obstetrics a) To provide an overview of the existing prognostic models and their qualities b) To evaluate the methodological challenges and potential solutions in developing a prognostic model for complications in pre-eclampsia Methods The following research methodologies were used: Delphi survey, systematic reviews and meta-analyses. Results 1. a) Maternal genotype and severe pre-eclampsia: 57 studies evaluated 50 genotypes; increased risk of severe pre-eclampsia with thromobophilic genes. b) Accuracy of tests in predicting pre-eclampsia complications: 37 studies evaluated 13 tests. No single test showed high sensitivity and specificity. c) Delphi survey of 18/20 obstetricians and 18/24 neonatologists identified clinically important maternal and neonatal outcomes and maternal and neonatal composite outcomes were developed. 2. Prospective risk of stillbirth and neonatal deaths in uncomplicated monochorionic and dichorionic twin pregnancies: 32 studies were included. In dichorionic twin pregnancies, the risk of stillbirths was balanced against neonatal death at 37 weeks' gestation. In monochorionic pregnancies, there was a trend towards increase in stillbirths after 36 weeks but this was not significant. 3. a) From 177 studies included, 263 obstetric prediction models were developed for 40 different outcomes, most commonly pre-eclampsia, preterm delivery, mode of delivery and small for gestational age neonates. b) The obstetric prognostic model challenge of dealing with treatment paradox was explored and seven potential solutions proposed by expert consensus. Conclusion I have identified the strength of association for genes associated with complications in pre-eclampsia, components for composite outcomes for reporting in studies on pre-eclampsia, and the optimal timing of delivery for twin pregnancies. My work has highlighted the gaps in prediction research in obstetrics and the limitations of individual tests in pre-eclampsia.
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Nilsson, Emma. "Genetic epidemiological studies of adverse pregnancy outcomes and the role of schizophrenia /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-590-9/.

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Wright, Erica, and n/a. "Gestational diabetes : a management approach to identify increased risk of an adverse pregnancy outcome." University of Canberra. Nursing, 1997. http://erl.canberra.edu.au./public/adt-AUC20061110.171500.

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Gestational diabetes (GDM) is a potentially serious disorder requiring timely diagnosis and management to prevent adverse maternal and fetal outcomes. Of increasing concern today, when treating the woman with GDM, is the need to provide every woman with an intensive management plan to optimise the likelihood of favourable pregnancy outcomes. Early identification of those women with GDM who require insulin therapy in addition to diet therapy would be beneficial in the planning and standardisation of clinical management protocols, to enhance pregnancy outcomes and increase cost benefits with improved allocation of resources. The aim of this study was to evaluate the ability of the fasting plasma glucose level (FPG) at diagnosis to predict an increased risk to the fetus and the need for insulin therapy in a pregnancy complicated by GDM. A prospective longitudinal study design and recruitment by convenience sample was used. Data were obtained from 327 women and their babies. Diagnosis of GDM was made by a 75 gram oral glucose tolerance test (OGTT) using Australasian Diabetes in Pregnancy Society (ADIPS) criteria with the exception of seven women diagnosed on a blood glucose level >11.1mmol/l. Following consent of the women data were collected by a self report questionnaire and the medical record system at three points; at first intervention, following delivery and at the postpartum OGTT. Demographic, social, medical, maternal and neonatal outcome data were collected. The management protocol was similar for all of the women. Following nutritional intervention any woman who could not meet the glycemic targets of <= 5mmol/l fasting and/or <= 6.5mmol/l two hours postprandial was commenced on insulin therapy. The women had a mean age of 32 years, body mass index (BMI) of 25.7 and parity of 2 (range 1-12). Diagnosis was made at an average of 30 weeks and 70 women required insulin therapy with a mean dose of 34 IU per day, commencing at a mean of 31 weeks gestation. Mean birthweight was 3400G. Of the babies 12% were >4000G. Congenital abnormalities occurred in 3%, neonatal morbidities in 2% and there was 1 death in utero. Logistic regression analysis found the following significant associations: Increasing maternal BMI was related to increasing FPG levels at diagnosis and the requirement of higher insulin doses. There was a negative linear relationship to weight gain. Ethnicity was associated with maternal BMI and ethnicity with BMI was associated with birthweight in the specific ethnic group. BMI with insulin therapy as a covariate and the FPG value at OGTT were predictive of persistent glucose intolerance in 14% of women postpartum. Each value of the OGTT was a significant predictor of the need for insulin therapy as a function of the week of gestation. The FPG level was the statistical model of best fit. A 50% probability for requiring insulin was reached with a FPG at diagnosis of 4.0 mmol/l if tested at 10 weeks gestation, 5.1mmol/l at 20 weeks and 6.1 mmol/l at 30 weeks (p<.001). These results support the substantive research aim of the study. The model has the power to predict the probability (risk) of requiring insulin therapy based on the maternal FPG level at the OGTT according to the week of gestation. The study results demonstrate that glucose intolerance is linked to a number of adverse maternal and fetal outcomes in a continuous and graded fashion. The degree of reversibility of maternal and fetal risk through therapeutic interventions such as nutrition therapy, blood glucose monitoring, exercise and active patient participation aimed at improving glucose tolerance is unknown. Therefore, the rationale for, and feasibility of, new treatment strategies such as the application of this statistical model as a management approach require large scale randomised intervention studies, oriented toward measuring maternal and fetal outcomes amongst different populations.
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Books on the topic "Adverse pregnancy outcomes"

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Rohilla, Minakshi, ed. Recurrent Pregnancy Loss and Adverse Natal Outcomes. Boca Raton: CRC Press, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9780429435027.

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J, Hitchcock Penelope, MacKay H. Trent, and Wasserheit Judith N, eds. Sexually transmitted diseases and adverse outcomes of pregnancy. Washington, D.C: ASM Press, 1999.

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J, Hitchcock Penelope, MacKay H. Trent, and Wasserheit Judith N, eds. Sexually transmitted diseases and adverse outcomes of pregnancy. Washington, D.C: ASM Press, 1999.

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Hitchcock, Penelope J., H. Trent MacKay, Judith N. Wasserheit, and Roberta Binder, eds. Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy. Washington, DC, USA: ASM Press, 1999. http://dx.doi.org/10.1128/9781555818210.

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Studies, Illinois Division of Epidemiologic. Adverse pregnancy outcomes in Illinois: County-specific prevalence and related infant mortality, 1989-1998. Springfield, IL: Illinois Dept. of Public Health, Division of Epidemiologic Studies, 2000.

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Fornoff, J. E. Birth defects and other adverse pregnancy outcomes in Illinois, 1997-2001: A report on county-specific incidence. Springfield, Ill: Illinois Dept. of Public Health, Division of Epidemiologic Studies, 2003.

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Fornoff, J. E. Birth defects and other adverse pregnancy outcomes in Illinois, 1995-1999: A report on county-specific incidence. Springfield, Ill: Illinois Dept. of Public Health, Division of Epidemiologic Studies, 2002.

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Illinois. Division of Epidemiologic Studies., ed. Birth defects and other adverse pregnancy outcomes in Illinois, 1998-2002: A report on county-specific incidence. [Springfield, Ill.]: Illinois Dept. of Public Health, Division of Epidemiologic Studies, 2004.

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Illinois. Division of Epidemiologic Studies., ed. Birth defects and other adverse pregnancy outcomes in Illinois, 2001-2005: A report on county-specific incidence. [Springfield, Ill.]: Illinois Dept. of Public Health, Division of Epidemiologic Studies, 2007.

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National Institutes of Health (U.S.), National Institute of Child Health and Human Development (U.S.), and National Heart, Lung, and Blood Institute, eds. Report of the Consensus Development Conference on the Effect of Corticosteroids for Fetal Maturation on Perinatal Outcomes, February 28, 1994-March 2, 1994. [Bethesda, Md.]: NIH, 1994.

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Book chapters on the topic "Adverse pregnancy outcomes"

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O’Brien, Kimberly O., and Carrie E. Thomas. "Iron Requirements and Adverse Pregnancy Outcomes." In Handbook of Nutrition and Pregnancy, 31–49. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-90988-2_2.

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Parker, Ashley L. "Racial Disparities in Adverse Pregnancy Outcomes." In Cultural Responsiveness in Assisted Reproductive Technology, 141–65. Cham: Springer Nature Switzerland, 2024. https://doi.org/10.1007/978-3-031-76204-8_9.

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Kutteh, William H. "Inherited and Acquired Thrombophilias and Adverse Pregnancy Outcomes." In Recurrent Pregnancy Loss, 67–73. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-27452-2_5.

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Sánchez, Pablo J. "Syphilis and Pregnancy." In Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy, 125–50. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818210.ch8.

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Brown, Zane A. "Genital Herpes and Pregnancy." In Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy, 245–58. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818210.ch14.

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Hillier, Sharon L. "Vaginal Ecology in Pregnancy." In Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy, 25–42. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818210.ch2.

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Minatoya, Machiko, Tomoyuki Hanaoka, and Reiko Kishi. "Environmental Exposures and Adverse Pregnancy-Related Outcomes." In Health Impacts of Developmental Exposure to Environmental Chemicals, 25–53. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-15-0520-1_2.

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Sharma, Shivani. "Management of pregnancy with recurrent preterm deliveries." In Recurrent Pregnancy Loss and Adverse Natal Outcomes, 33–42. Boca Raton: CRC Press, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9780429435027-4.

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Siwatch, Sujata. "Investigation and management of recurrent cholestasis of pregnancy." In Recurrent Pregnancy Loss and Adverse Natal Outcomes, 61–67. Boca Raton: CRC Press, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9780429435027-7.

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Muthyala, Tanuja. "Approach to women with recurrent first-trimester abortions: Need of the hour." In Recurrent Pregnancy Loss and Adverse Natal Outcomes, 1–15. Boca Raton: CRC Press, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9780429435027-1.

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Conference papers on the topic "Adverse pregnancy outcomes"

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"Noise Exposure during Pregnancy: Influence on Adverse pregnancy outcomes." In 2022 International Conference on Biotechnology, Life Science and Medical Engineering. Clausius Scientific Press, 2022. http://dx.doi.org/10.23977/blsme.2022034.

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Moon, Hye Yeon, Yung-Taek Ouh, Kyung Jin Min, Jae-Kwan Lee, Nak woo Lee, and Geum Joon Cho. "Adverse pregnancy outcomes in women with cancer during pregnancy." In ASGO 2023. Korea: Korean Society of Gynecologic Oncology, 2024. http://dx.doi.org/10.3802/jgo.2024.35.s1.0183.

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Ouh, Yung-Taek, Seoyoung Moon, Min Kyung Kwak, Kyung-Jin Min, Geum Joon Cho, Jae Kwan Lee, and Nak Woo Lee. "Assessing adverse pregnancy outcomes and fetal malformations in cancer diagnosed during pregnancy." In The 39th Annual Meeting of the Korean Society of Gynecologic Oncology. Korea: Korean Society of Gynecologic Oncology, 2024. http://dx.doi.org/10.3802/jgo.2024.35.s2.fp-ot1.

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Kammerer, Susanne. "No adverse pregnancy outcomes in patients exposed to baricitinib." In 7th Congress of the SPIN, edited by Peter van de Kerkhof. Baarn, the Netherlands: Medicom Medical Publishers, 2022. http://dx.doi.org/10.55788/3f9a9e76.

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Fontaine, Alexandra, and Emily Meale. "A Review of Risk Factors, Adverse Outcomes, and Counseling Strategies Among Pregnant Individuals with Eating Disorders." In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.131_2024.

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Background: Eating disorders (EDs) among women of childbearing age have become more prevalent on the global level. Identifying at-risk populations of women having EDs before, during, or after pregnancy is essential for clinicians to improve treatment and decrease the likelihood of negative maternal and/or fetal outcomes. Purpose: The purpose is to determine risk factors for women who have EDs throughout pregnancy, to identify negative pregnancy outcomes of women suffering from EDs, and to explore treatment and counseling options through the postpartum period. Methods: This literature review mainly utilizes sources from PubMed and the National Institute of Health databases. An expansive list of search terms were used, such as: pregnancy, EDs, anorexia nervosa, bulimia nervosa, binge eating disorder, avoidant/restrictive food intake disorder, mental health, age, counseling, depression, anxiety, postpartum, and breastfeeding. Results: Younger women with a history of EDs or who are actively suffering from EDs are at high risk for negative maternal and fetal outcomes in pregnancy. EDs can be identified by clinicians asking thorough medical histories, highlighting key terms of common vulnerabilities amongst this patient population. A multidisciplinary team approach consisting of clinicians, psychologists, nutritionists, and hospitalists are important for treating pregnant women with EDs. Conclusion: EDs in pregnancy are considered high risk and can lead to severe negative outcomes. EDs should be identified early on and treated through the postpartum period. More research on treatment and counseling for this patient population continues to be a gap in the literature and in the clinic.
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Alex, R. M., D. Mann, A. Azarbarzin, D. Vena, L. Gell, A. Wellman, S. Redline, and S. A. Sands. "Adverse Pregnancy Outcomes of Airflow Limitation During Sleep: Nulliparous Pregnancy Outcomes Study Monitoring Mothers-to-Be (nuMoM2b)." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4815.

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Robijn, Annelies, Bronwyn Brew, Megan Jensen, Gustaf Rejnö, Cecilia Lundholm, Vanessa Murphy, and Catarina Almqvist. "Asthma exacerbations during pregnancy increase risk of adverse perinatal outcomes." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.4643.

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Çetin, Çiğdem, Tuğba Saraç-Sivrikoz, Müge Ateş-Tikiz, Sibel Zarali, Ayşenur Ersoy, Yasemin Yalçinkaya, Ahmet Gül, et al. "P73 The relationship between pregnancy, disease activity and adverse pregnancy outcomes in systemic lupus erythematosus." In 12th European Lupus Meeting. Lupus Foundation of America, 2020. http://dx.doi.org/10.1136/lupus-2020-eurolupus.118.

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Tedeschi, Sara K., Hongshu Guan, Alexander Fine, Karen H. Costenbader, and Bonnie L. Bermas. "CE-03 Organ-specific systemic lupus erythematosus activity during pregnancy is associated with adverse pregnancy outcomes." In Abstracts of the Third Biannual Scientific Meeting of the North and South American Lupus Community, Armonk, New York, USA, September 29 – October 1, 2016. Lupus Foundation of America, 2016. http://dx.doi.org/10.1136/lupus-2016-000179.82.

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Shimada, Hiromi, Risa Wakiya, Mai Mahmoud Fahmy Mansour, Shusaku Nakashima, Mikiya Kato, Taichi Miyagi, Tomohiro Kameda, and Hiroaki Dobashi. "AB0561 RISK FACTORS FOR ADVERSE PREGNANCY OUTCOMES AND LOW RISK FACTORS FOR ADVERSE PREGNANCY OUTCOMES AND LOW APGAR SCORES OF NEWBORNS IN WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.4530.

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Reports on the topic "Adverse pregnancy outcomes"

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Shey Wiysonge, Charles. Does additional social support during at-risk pregnancy improve perinatal outcomes? SUPPORT, 2016. http://dx.doi.org/10.30846/1608104.

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Additional social support has been advocated for socially disadvantaged pregnant women because they are at greater risk of experiencing adverse birth outcomes. Support may include advice and counselling (e.g. about nutrition, rest, stress management, or the use of alcohol), tangible assistance (e.g. transportation to clinic appointments, or household help), and emotional support (e.g. reassurance, or sympathetic listening). The additional social support may be delivered by multidisciplinary teams of healthcare workers or lay health workers during home visits, clinic appointments or by telephone.
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Veleva, Galabitza, Asen Nikolov, Suzana Nashar, Konstantsa Neykova, and Maria Yunakova. Perinatal Morbidity and Other Severe Adverse Pregnancy Outcomes Associated with Treatment of Cervical Intraepithelial Neoplasia. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, March 2019. http://dx.doi.org/10.7546/crabs.2019.03.16.

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Li, Yanhui, and Cuiju Hua. Comparison of the Efficacy and Subsequent Pregnancy Outcomes of High-intensity Focused Ultrasound and Uterine Artery Embolization in the Chinese Population: Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2022. http://dx.doi.org/10.37766/inplasy2022.10.0053.

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Review question / Objective: The combination of high-intensity focused ultrasound (HIFU), and uterine artery embolization (UAE) with uterine curettage has been proposed as a therapy strategy for cesarean scar pregnancy (CSP), which can provide a high success rate while reducing blood loss, adverse events, hospital time and cost. Therefore, we performed this meta-analysis to assess the effects of this combination therapy on the efficacy, safety, and pregnancy outcomes in patients with CSP. Eligibility criteria: (1) Study design: Cohort, case-control, or randomized controlled trials that compare the efficacy, safety, and recurrence of UAE combined with curettage and HIFU combined with uterine scraping in the treatment of cesarean section scar pregnancy. (2) Outcome: Success rate, blood loss, time of β-hCG normalization, adverse events, length of stay, hospital costs, menstrual recovery, re-pregnancy status, and pain score.
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Moon, Shinje, Ka Hee Yi, and Young Joo Park. Risk of Adverse Pregnancy Outcomes in Young Women with Thyroid Cancer: Systemic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0075.

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Viswanathan, Meera, Jennifer Cook Middleton, Alison Stuebe, Nancy Berkman, Alison N. Goulding, Skyler McLaurin-Jiang, Andrea B. Dotson, et al. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions. Agency for Healthcare Research and Quality (AHRQ), April 2021. http://dx.doi.org/10.23970/ahrqepccer236.

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Background. Untreated maternal mental health disorders can have devastating sequelae for the mother and child. For women who are currently or planning to become pregnant or are breastfeeding, a critical question is whether the benefits of treating psychiatric illness with pharmacologic interventions outweigh the harms for mother and child. Methods. We conducted a systematic review to assess the benefits and harms of pharmacologic interventions compared with placebo, no treatment, or other pharmacologic interventions for pregnant and postpartum women with mental health disorders. We searched four databases and other sources for evidence available from inception through June 5, 2020 and surveilled the literature through March 2, 2021; dually screened the results; and analyzed eligible studies. We included studies of pregnant, postpartum, or reproductive-age women with a new or preexisting diagnosis of a mental health disorder treated with pharmacotherapy; we excluded psychotherapy. Eligible comparators included women with the disorder but no pharmacotherapy or women who discontinued the pharmacotherapy before pregnancy. Results. A total of 164 studies (168 articles) met eligibility criteria. Brexanolone for depression onset in the third trimester or in the postpartum period probably improves depressive symptoms at 30 days (least square mean difference in the Hamilton Rating Scale for Depression, -2.6; p=0.02; N=209) when compared with placebo. Sertraline for postpartum depression may improve response (calculated relative risk [RR], 2.24; 95% confidence interval [CI], 0.95 to 5.24; N=36), remission (calculated RR, 2.51; 95% CI, 0.94 to 6.70; N=36), and depressive symptoms (p-values ranging from 0.01 to 0.05) when compared with placebo. Discontinuing use of mood stabilizers during pregnancy may increase recurrence (adjusted hazard ratio [AHR], 2.2; 95% CI, 1.2 to 4.2; N=89) and reduce time to recurrence of mood disorders (2 vs. 28 weeks, AHR, 12.1; 95% CI, 1.6 to 91; N=26) for bipolar disorder when compared with continued use. Brexanolone for depression onset in the third trimester or in the postpartum period may increase the risk of sedation or somnolence, leading to dose interruption or reduction when compared with placebo (5% vs. 0%). More than 95 percent of studies reporting on harms were observational in design and unable to fully account for confounding. These studies suggested some associations between benzodiazepine exposure before conception and ectopic pregnancy; between specific antidepressants during pregnancy and adverse maternal outcomes such as postpartum hemorrhage, preeclampsia, and spontaneous abortion, and child outcomes such as respiratory issues, low Apgar scores, persistent pulmonary hypertension of the newborn, depression in children, and autism spectrum disorder; between quetiapine or olanzapine and gestational diabetes; and between benzodiazepine and neonatal intensive care admissions. Causality cannot be inferred from these studies. We found insufficient evidence on benefits and harms from comparative effectiveness studies, with one exception: one study suggested a higher risk of overall congenital anomalies (adjusted RR [ARR], 1.85; 95% CI, 1.23 to 2.78; N=2,608) and cardiac anomalies (ARR, 2.25; 95% CI, 1.17 to 4.34; N=2,608) for lithium compared with lamotrigine during first- trimester exposure. Conclusions. Few studies have been conducted in pregnant and postpartum women on the benefits of pharmacotherapy; many studies report on harms but are of low quality. The limited evidence available is consistent with some benefit, and some studies suggested increased adverse events. However, because these studies could not rule out underlying disease severity as the cause of the association, the causal link between the exposure and adverse events is unclear. Patients and clinicians need to make an informed, collaborative decision on treatment choices.
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Seedu, Tegwende, Eden Manly, Taylor Moore, Laura Anderson, Beth Murray-Davis, Diane Ménage, Rebecca Seymour, and Rohan D'Souza. Understanding maternal morbidity from the perspectives of women & people with pregnancy experience: a concept analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2022. http://dx.doi.org/10.37766/inplasy2022.12.0097.

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Review question / Objective: This study will investigate the question: what is maternal morbidity from the perspective of women and people with pregnancy experience? The objectives of this study are to: 1. describe the conditions and events that WPPE conceptualize as maternal morbidities, 2. identify the themes that arise across WPPE’s experiences, such as regional and cultural differences and similarities, and 3. produce a schematic representation of how WPPE conceptualize maternal morbidity. Background: Maternal morbidity is primarily concerned with adverse pregnancy-related outcomes, excluding mortality, among the pregnant and postpartum population. Although presently a global concern, maternal morbidity was not always prioritized in healthcare and research. The increased attention towards maternal morbidity in recent decades was preceded by the initial prioritization of maternal mortality as the dominant indicator of maternal health, leading to its decreasing trend over the decades.(1) Standards of maternal care are no longer solely defined by preventing mortality; they now include preventing and better treatment of maternal morbidity to improve patient outcomes. However, there are no universally accepted criteria for describing maternal morbidity. Less evidence is available on the views of Women and People with Pregnancy Experience (WPPE), and a knowledge gap exists in conceptualizing maternal morbidity from their perspective.
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Caffera, Marcelo, Juanita Bloomfield, and Ana Balsa. The Effect of Acute and Intensive Exposure to Particulate Matter on Birth Outcomes in Montevideo. Inter-American Development Bank, September 2014. http://dx.doi.org/10.18235/0011661.

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This study explores the impact of air pollution on adverse birth outcomes. The study focuses on the effect of breathable particulate matter with diameter of 10 micrometers or less (PM10) on the likelihood of premature birth and low birth weight (LBW). The study exploits the fact that in 2011 the ashes and dust resulting from the eruption of the Puyehue volcano in Chile substantially increased exposure to PM10 in Montevideo, Uruguay. Using prenatal and birth data from the Perinatal Information System for 2010-2012, it is found that increases in quarterly averages of PM10 concentrations beyond 50 µg/m3 decrease birth weight and increase the likelihood of LBW and prematurity at increasing rates. The results also suggest that the effect of PM10 on birth weight works mainly through a higher likelihood of prematurity, rather than through intrauterine growth retardation. The effects increase with each trimester of pregnancy: exposure during the third trimester is the most dangerous.
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Rosales, María Fernanda. Impact of Early Life Shocks on Human Capital Formation: El Niño Floods in Ecuador. Inter-American Development Bank, December 2014. http://dx.doi.org/10.18235/0011668.

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A growing body of research argues that early adverse experiences have lasting effects not only on later health outcomes, but also on human capital accumulation. This paper investigates the persistent effect of negative shocks early in life on children's health and cognitive outcomes, and explores whether shocks at certain periods matter more than others. The paper exploits the geographic intensity of extreme floods during the 1997-1998 El Niño phenomenon in Ecuador as a source of exogenous variation in children's exposure to a negative shock at different periods early in life. It is shown that children exposed to severe floods in utero, especially during the third trimester, are shorter in stature five and seven years later. Also, children affected by the floods in the first trimester of pregnancy score lower on cognitive tests. Potential mechanisms are explored by studying how exposure to the El Niño shock affected key inputs to the production of children's human capital: birth weight and family inputs (income, consumption, and breastfeeding). Children exposed to El Niño floods, especially during the third trimester in utero, were more likely to be born with low birth weight. Furthermore, households affected by El Niño 1997-98 suffered a decline in income, total consumption, and food consumption in the aftermath of the shock. Moreover, exposure to El Niño floods decreased the duration of exclusive breastfeeding and increased the duration of non-exclusive breastfeeding. Falsification exercises suggest that selection concerns such as selective fertility, mobility, and infant mortality do not drive these results.
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Rosen, Michael, C. Matthew Stewart, Hadi Kharrazi, Ritu Sharma, Montrell Vass, Allen Zhang, and Eric B. Bass. Potential Harms Resulting From Patient-Clinician Real-Time Clinical Encounters Using Video-based Telehealth: A Rapid Evidence Review. Agency for Healthcare Research and Quality (AHRQ), September 2023. http://dx.doi.org/10.23970/ahrqepc_mhs4telehealth.

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Objectives. To review the evidence on harms associated with patient-clinician real time encounters using video-based telehealth and determine the effectiveness of any related patient safety practices (PSPs). PSPs are interventions, strategies, or approaches intended to prevent or mitigate unintended consequences of healthcare delivery and improve patient safety. This review provides information that clinicians and health system leaders need to determine how to minimize harms from increasing real-time use of telehealth. Methods. We followed rapid review processes of the Agency for Healthcare Research and Quality Evidence-based Practice Center Program. We searched PubMed, EMBASE, and Cochrane to identify eligible studies published from 2012 to 2022, supplemented by a search for unpublished evaluations and white papers. Outcomes of interest included: adverse events (any harm to patients due to medical care), other specified harms (i.e., preventable hospitalizations, inappropriate treatment, missed or delayed diagnoses, duplication of services, privacy breaches), and implementation factors for any PSPs. Findings. Our search retrieved 7,155 citations, of which 23 studies (including 6 randomized controlled trials [RCTs]) were eligible for review. Fourteen studies reported on adverse events or unintended effects of telehealth; these studies were conducted in diverse settings, with four studies in behavioral health, two each in rehabilitation, transplant, and Parkinson’s care, and one each in postoperative, termination of pregnancy, community health, and hospital-at-home settings. Adverse events such as death, reoperation, infection, or major complications were infrequent in both telehealth and usual care groups, making it difficult to find statistically significant differences. One RCT found telehealth resulted in fewer medication errors than standard care. Thirteen studies examined preventable hospitalizations or emergency department (ED) visits and reported mixed findings; six of these studies were in postoperative care and two were in urological care. Of the 6 RCTs, 3 showed no difference in risk of hospitalization or ED visits for telehealth compared to usual care, and 3 showed reduced risk for patients receiving telehealth. We found no studies on the effectiveness of PSPs in reducing harms associated with real-time telehealth. Conclusions. Studies have evaluated the frequency and severity of harms associated with real-time video-based telehealth encounters between clinicians and patients, examining a variety of patient safety measures. Telehealth was not inferior to usual care in terms of hospitalizations or ED visits. No studies evaluated a specific PSP. More research is needed to improve understanding of harms associated with real-time use of telehealth and how to prevent or mitigate those harms.
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Cassell, Gail H. Risk Factors for Chorioamnion Infection and Adverse Pregnancy Outcome Among Active-Duty Military Women and Dependent Women. Fort Belvoir, VA: Defense Technical Information Center, October 1997. http://dx.doi.org/10.21236/ada342258.

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