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Dissertations / Theses on the topic 'Adhezní'
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1
Candráková, Simona. "Adhezní vlastnosti semi-IPN hydrogelů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2020. http://www.nusl.cz/ntk/nusl-433088.
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This Diploma thesis deals with optimization of the hydrogel preparation with various additions of substances affecting adhesion, studying the adhesion of prepared hydrogel systems and modifying their adhesion properties. Prepared hydrogels were agarose, alginate and gellan polymer systems with additions of acrylic acid, acrylamide, calcium chloride and Tween 20. The experimental part of the diploma thesis focuses first on optimizing the preparation of individual hydrogels, from which, according to certain criteria, suitable representatives were selected to study adhesion and its controlled modification. Agarose and gellan hydrogels were selected as suitable representatives, which were then used in rheological measurements. Based on these measurements, the effect of the adhesive force and the adhesive work of individual materials was evaluated. It was found that the best adhesion properties of the materials used are unadjusted hydrogels, in the case of hydrogels with the addition of another substance, a negative effect on adhesion was observed, when the adhesion force was reduced and also the adhesion work was reduced.
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Jandásek, Martin. "Dynamicky vyvážený rezonanční adhezní tester." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-399347.
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This diploma thesis is dedicated to the development of mobile resonance-adhesion tester TriTec. The aim of this thesis is to improve the parameters of the tester in comparison to the previous version of tester, especially to minimize the vibrations of the tester while running without load, and to the make long-distance transportation of tester easier. The first part of thesis was aimed on history of development of TriTec tester, causes of it´s problems and on analysis of vibration minimization possibilities. As a best solution is considered a rotational balance mechanism, which was designed in next part of thesis. After that a new front wheel drive and an user interface conception were designed. The modified tester reaches all the deserved parameters and is able to compete static resonance-adhesion testers by it´s lower price and high mobility.
3
Janová, Petra. "Adhezní spolupůsobení lepidla s konstrukčním dřevem." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2020. http://www.nusl.cz/ntk/nusl-409760.
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This labor is based on penetration of adhesives into a wood cell walls. It focuses mainly on adhesives that are currently used for construction purposes. It also contains a methodics of selecting adhesives and wood, which will be used for glued joints and summarizes the methods used for detect these adhesives in the wood cell wall. It experimentally verifies the appropriate selection of the dye-solvent combination used in the adhesive.
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Švestková, Dana. "Vliv adhezní mezivrstvy na lomově-mechanické chování kompozitu PP + anorganické plnivo." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2011. http://www.nusl.cz/ntk/nusl-216785.
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The diploma thesis was dealt with the study of system PP and particular filler, specifically PPH and like a filler was used commercially available CaCO3 (SOCAL P3). This type of filler is declared by the producer as a filler without surface treatment. The submitted thesis had a goal to find and testing the suitable method and methodology for defined surface treatment of the filler. This is the first step for systematic study of influence the various types of adhesive layer on mechanical properties of declared composite. The plasma discharge behind static pressure was used for the surface treatment of the fillers. These fillers were afterwards analyzed by using of sedimentation analysis, infra - red spectroscopy (FT-IR) and scan electron microscopy (SEM). The composites with various volume part of the fillers were prepared in PIB and studied by short-time tests. Regarding to experimental demand there wasn't possible to realize the whole originally intended program i. e. study of influence the different types of adhesive layer, including to form the model for FEM approach. Nevertheless finding and testing the suitable method of surface treatment is completely basic for the others study. The above mentioned method was used in this application for the first time and it is possible to consider this process like an original approach.
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Dombková, Julie. "Cílená příprava kompozitu na bázi PP + anorganické mikro resp. nano anorganické plnivo s různou adhezní mezivrstvou." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2012. http://www.nusl.cz/ntk/nusl-216822.
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The diploma thesis studies composite of PP and filler particle. As a particle filler was used commercially available CaCO3 (SOCAL 31). The submitted thesis had a goal to find new approaches and technologies of filler surface treatment in order to improve properties of composite materials. The plasma discharge behind static pressure was used for the surface treatment of the fillers. These fillers were afterwards analyzed by using of sedimentation analysis, turbidimetry, infra-red spectroscopy (FT-IR), X-ray diffraction analysis (XRD), scan electron microscopy (SEM), transmission electron microscopy and particle size distribution by laser diffraction. The composites with various volume parts of the fillers were prepared in PIB and studied by short-time tests. Furthermore, the influence of an adhesive layer on fracture mechanical properties of prepared composite was study. Regarding to experimental demand, there was not possible to realize long-term mechanical properties.
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Janošík, Petr. "Mechanické vlastnosti biokompozitů." Master's thesis, Česká zemědělská univerzita v Praze, 2016. http://www.nusl.cz/ntk/nusl-258114.
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Goal of this diploma thesis was to describe mechanical properties of epoxy resins containing organical fibers and to experimentally evaluate the effect of the fiber length with various concentrations on final mechanical property of composit material. First part of the diploma thesis is dedicated to literature review which describes general properties of fiber composites, materials which they are made of, and mechanical trials. In chapter called Methodics, materials used for experimental research are described. Process of sample preparation and mechanical trials, which were used for the test, are also described there. Last part of the diploma thesis is dedicated to evaluation of results of executed mechanical trials on composites with fiber support of various lengths and concentrations
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Machatka, Martin. "Experimentální výzkum pískování v kontaktu kola a kolejnice." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2014. http://www.nusl.cz/ntk/nusl-231057.
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Presented master's thesis is focused on the experimental research of the sanding parameters in order to improve adhesion in the contact between wheel and rail. Sanding is the application of the sanding material directly in the wheel/rail contact. It is still common, most effective and traditional way how to deal with low adhesion problem, which is mainly caused by environmental contaminants. Research is important for the better understanding of the sanding process and also provides data, which are necessary for it's optimization and efficiency improvement. Newly developed twin-disc machine was used to carry out the presented experimental research. The influence of common contaminants on the adhesion is investigated, considering various operating parameters. Different amount of the applied sand is used to increase adhesion in the contaminated contact at various slip and rolling speed. Results show, that there is the amount of the sand, from which no significant adhesion increase occur. Obtained findings and the results presented in this thesis will be used to optimize sanding system, which will contribute to reduce cost associated with sanding and low adhesion.
8
Novák, Petr. "Mobilní tester závěsu automobilového kola." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2016. http://www.nusl.cz/ntk/nusl-254403.
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This diploma thesis deals with the constructional design, followed by the manufacturing of the tester for non-invasive diagnostics of cars shock absorbers. It is a resonant adhesive tester with 3 mm lift of measuring platform, in contrast with standardly manufactured testers with 6 mm lift. By reducing lift of measuring platform is eliminated failure of EUSAMA methodology for problematic vehicles. In the thesis are also included verifications of tester function and comparative measurements with standardly manufactured tester.
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Nečasová, Barbora. "Adheze lepených spojů fasádních obkladů z materiálů na bázi dřeva." Doctoral thesis, Vysoké učení technické v Brně. Fakulta stavební, 2019. http://www.nusl.cz/ntk/nusl-401594.
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The presented dissertation thesis is focused on investigating the adhesive properties of façade cladding made of wood and wood-based materials in combination with flexible adhesion/assembly systems. The systems allow the implementation of effective construction joints and provide a solution with uniform stress distribution which allows the transfer of heavy loads, while simultaneously reducing the weight of the entire structure, which is also often connected with substantial cost reductions. Despite all that, little attention has been paid to this area so far. It is not a solution which is properly embodied in technical standards or in designers´, architects´ and contractors´ awarenesses. The aim of this dissertation is to characterise adhesive properties of selected façade cladding representatives made of wood and wood-based materials for the purposes of bonded joint application in a ventilated façade system. To define adhesion of façade joints, numerical and experimental methods are used, taking also various limit conditions into account. The main conclusion of the dissertation is the characterisation of basic parameters which influence adhesion, effectiveness and quality of façade glued joints. The secondary conclusion is the compilation of a simple methodical procedure for testing and implementing façade glued joints. The dissertation also makes a contribution by extending the current state of knowledge of façade adhesive joints.
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Gabriel, Tomáš. "Konstrukce zkušebního zařízení pro testování adheze a hluku v kontaktu kola a kolejnice." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-417765.
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This master’s thesis is dedicated to the design of an experimental rig that allows investigation of causes for noise during tram’s passing of a track curve and the developement of means to mitigate this noise. The opening section of this thesis contains theoretical background for the tribological mechanics of wheel-rail contact with emphasis on the process of noise generation, followed by an overview of laboratory tst rigs with similar purpose. Design itself is centered around the implementation of the dynamic model of wheel-rail contact using real tram wheel. Resulting test rig allows measurement of the adhesion characteristic in tangential and lateral directions and recording of the generated noise while an angle of attack is set.
11
Dražil, Luboš. "Nové typy kompozitů pro sanaci stavebních konstrukcí s důrazem na zvýšení korozní odolnosti výztuže." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2013. http://www.nusl.cz/ntk/nusl-225898.
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This thesis is dedicated to the degradation of reinforced concrete structures, their causes and consequences of the waveforms. This thesis describes how the protection of concrete structures against these negative effects. The practical part of the work was focused on the development of new types of repair materials with added value in the form of corrosion inhibitor. In this part of the work was done adhesive bridge and development of repair materials for hand and machine application.
12
Fecko, Peter. "Mikrostruktury mimikující povrch tlapky gekona." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2019. http://www.nusl.cz/ntk/nusl-400722.
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Adhezní schopnosti gekona byly předmětem mnoha studií a inspirací pro vytvoření mnoha napodobenin. Tato práce navrhuje vlastní verzi umělých gekoních struktur ve tvaru mikroskopických pilířů, které by vykazovaly adhezní vlastnosti srovnatelné s tlapkou gekona. Vyrobeny byli struktury z polymeru Parylen C pomocí fotolitografie a technik na leptání křemíku. Dalším cílem bylo různými metodami pro modifikaci povrchu a charakterizaci vytvořených struktur, které určí adhezní síly těchto povrchů, před a po modifikacích.
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Slavík, Jan. "Zarovnání excitabilních buněk na multielektrodových polích." Doctoral thesis, Vysoké učení technické v Brně. CEITEC VUT, 2021. http://www.nusl.cz/ntk/nusl-442346.
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Práce se zabývá zarovnáváním excitabilních buněk na multielektrodových polích. Nejprve bylo analyzováno zarovnávání excitabilních buněk. Byly použity embryonální neurony z hippocampusu potkanů a HL-1 buňky, které jsou odvozeny z AT-1 linie nádorových myších atriálních kardiomyocytů. Zarovnávání bylo testováno na drážkovaných površích a na površích s materiály s různou buněčnou afinitou. Bylo prokázáno, že na drážkových površích se ve směru drážek zarovnávají neurony i HL-1 buňky, ale na površích s různou chemickou affinitou se zarovnávají pouze neurony. Dále byly vyrobeny vlastní multielektrodová pole, na těchto multielektrodových polích byly kultivovány HL-1 buňky a byl změřen a analyzován akčních potenciál HL-1 buněk. Cílem bylo prokázat, že je možné měřit akční potenciál na vyrobených multielektrodových polích. Pro zarovnání buněk na multielektrodovém poli bylo vyrobeno speciální multieletrodové pole s uniformním povrchem. Toto multielektrodové pole je nazýváno planární multielektrodové pole. Planární multielektrodové pole bylo vyrobeno speciálním vyrobním procesem. Vrstvy planárního multielektrodového pole byly deponovány na pomocný substrát v opačném pořadí. Pomocný substrátem pro depozici byla křemíková deska, na který byla nadeponována další pomocná vrstva zlata. Horní izolační vrstva planárního multielektrodové pole byla deponována jako první a nejspodnější vrstva substrátu byla nadeponována jako poslední. Planární multielektrodové pole i s pomocnou zlatou vrstvou bylo strhnuto s křemíku díky nízké adhezi zlata ke křemíku a planární multielektrodové pole se otočilo vzhůru nohama. Pomocná zlatá vrstva byla odstraněna mokrým leptadlem a tím bylo planární multielektrodové pole dokončeno. Na planárním multielektrodovém poli byly zarovnány HL-1 buňky do pruhů chemickou metodou pomocí kombinace otisku adhezní látky a následným potažení neotisklých ploch anti-adhezní látkou. Elektrofyziologické vlastnosti zarovnaných HL-1 buněk byly změřeny pomocí planárního multielektrodového pole. Tímto experimentem byla představena výrobní technologie pro výrobu planárních multielektrodových polí a toto planární multielektrodové pole bylo úspěšně testováno pro zarovnání HL-1 buněk na jeho povrchu kombinací otisku adhezní látky a potahování antiadhezivním činidlem.
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Mareš, Jiří. "Modifikace charakteru rozhraní substrát-nástřik vrstev deponovaných technologiemi žárového nanášení pomocí technologie elektronového paprsku." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-231939.
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Tato práce je zaměřena na modifikaci charakteru rozhraní substrát-nástřik NiCrAlY povlaků nanesených pomocí technologie vodou stabilizované plazmy na substráty z oceli S235JRC+C. Přetavení žárové vrstvy elektronovým paprskem bylo zvoleno jako technologie pro modifikaci a dvě různé modifikace byly zkoumány. V práci byl proveden pokus o stanovení vlivu modifikací na adhezní vlastnosti nástřiku. Dále jsou v práci prezentovány analýzy mikrostruktury, fázového a chemického složení a mikrotvrdosti ve stavu před a po modifikaci. Během studie bylo zjištěno, že dochází ke změnám fázového složení jak během depozice, tak během modifikace elektronovým paprskem. Modifikace elektronovým paprskem způsobila roztavení oxidů původní mikrostruktury nástřiku, které následně rekrystalizovaly na povrchu modifikované vrstvy. Dalším získaným poznatkem bylo, že dochází ke snížení mikrotvrdosti po modifikaci, což bylo způsobeno odstraněním oxidů z mikrostruktury a promícháním materiálu substrátu a původního nástřiku. Adheze nástřiků v as sprayed stavu byla kvantifikována. V případě nástřiků modifikovaných elektronovým paprskem přesná kvantifikace nebyla možná, z důvodu předčasného porušení na rozhraní nástřik-adhezivní pojivo během adhezních testů.
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Mikulec, Roman. "Systémové srovnání měření adheze vozovky." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-233151.
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This thesis presents a comparison of different methods for measuring road surface skid resistance and an assessment of whether there is a functional dependency in between measurement results of these methods. It consists of a description of the physical quantities, which are measured by these methods and equipment used for these measurements. The work includes the measurement and comparison of measurement outputs with each other. Among the measurement methods there can be seen similar development of their values, with two exceptions there is similar difference between the results of the measurement methods. When comparing the results XL Meter instrument seemed more accurate than the RaceLogic due to its higher frequency of data recording. By using numerical method of comparison between XL Meter device and multipurpose device TRT there was a constant by which the results differed from each instrument, with value of 0,35, using the method of interspacing the resulting differences of values by a line, the resulting constant by which the results differed between the devices had the value of 0,33.
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Pálesch, Erik. "Charakterizace adheze tenkých vrstev plazmových polymerů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2010. http://www.nusl.cz/ntk/nusl-216641.
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The diploma thesis deals with characterization of adhesion of plasma polymer films deposited on silicon wafers. The samples included organosilicon thin films based on tetravinylsilane monomer prepared by plasma-enhanced chemical vapour deposition. Scratch test was used to characterize film adhesion employing nanoindentation measurements. Adhesion of plasma polymer films of different mechanical properties and film thickness was analyzed by normal and lateral forces, friction coefficient, and scratch images obtained by scanning probe microscope working in atomic force microscopy mode.
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Petříček, Tomáš. "Adheze spojů asfaltových pásů mechanicky kotvených." Doctoral thesis, Vysoké učení technické v Brně. Fakulta stavební, 2014. http://www.nusl.cz/ntk/nusl-233827.
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One-layer mechanical fastening waterproofing systems are often used within the compositions of flat roofs. Although in case of plastic based systems it is a common solution, for asphalt felts it handles about a relatively new approach, since the application of asphalt has a long history in the building industry. There are some key factors which all of the one-layer mechanically fastening systems should meet, especially water-resistance and resistance against the suction of wind. The application of dynamic loads on the joints may damage the bonds, which may lead to leakage of water. In particular the most delicate locations are the anchoring points at places where the waterproofing sheets are not connected mutually and the wind is captured. The characteristics of mechanically fastening waterproofing membranes may be verified by a specific test which is able to simulate the winds suction force, nonetheless it is quite expensive. Throughout the solution of the presented work an equipment was designed to observe the behaviour of roof compositions on smaller segments while taking into account the fastening elements, thus bringing the results closer to reality. In the first phase the presented dissertation aims to look at the possibilities of comparison of mechanically fastening bitumen reinforced sheets in a way, that they would show the extent to which the joints depend on the parameters of bitumen sheet - like the quality of the bitumen mass, the type bearing linen, the thickness of the layer or just the width of strip overlap. In the next phase the research was focused on the extent at which the strength of the resulting mechanically fastened joints is affected by the placement of fastenings elements within the strip overlap, including the possibilities when the distances from the edges of the bitumen strip cannot be maintained or because of improper geometry of fastening elements. The measurements were performed on both variants of flat roofs, thermally insulated
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Šabík, Matúš. "Analýza jízdních manévrů vozidel za snížené adheze." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2016. http://www.nusl.cz/ntk/nusl-241210.
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This master’s thesis deals with driving maneuvers at low coefficient of adhesion, especially in winter season. It includes a list of adhesion coefficients on many surfaces, published by various authors. Figures were through the use of statistical methods divided into normal and exceeding. There are described terms having impact on adhesion. For determination of adhesion was used tests like emergency braking, circle test and slalom. The major part contains specification of used vehicles, surfaces, weather conditions, measuring devices and realized tests. In addition to using accelerometer, there was a successful attempt to use timekeeping facilities to determine deceleration of vehicle. Acquired data were processed and compared to another publications.
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Hortová, Petra. "Virtuální model rezonančního adhezního testu závěsu kola dle EUSAMA." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2009. http://www.nusl.cz/ntk/nusl-228609.
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Thesis deals with problems about areas of a non-assembling diagnostics namely resonant adhesive tester according to an EUSAMA methodology. Result of the methodology is a technical condition examination of dampers. However with regard to testing of whole suspension and damping vehicle system are results distorted by influence of testing conditons and another vehical components. Goal of thesis is analysis limits of practical use resonant adhesive tester for a quality checking of mount wheels damping. Problems are solved by a virtual simulation in a program Adams/View where is created a real model of vehical axle of Skoda Roomster TDI 1.4. In the model is consequently simulated possible functional characteristics and abrasions of single components which influence the methodology. Virtual model will be using for research activity of Institute of machine and industrial design Faculty of mechanical ingeneering Brno University of technology.
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Širmerová, Marcela. "Adheze jednobuněčných řas Chlorella vulgaris na pevné povrchy." Doctoral thesis, Česká zemědělská univerzita v Praze, 2015. http://www.nusl.cz/ntk/nusl-259619.
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Although adhesion of bacteria and yeast have been extensively studied by a wide range of experimental and theoretical approaches, significantly less attention has been focused on microalgal adhesion to solid materials. Therefore this doctoral thesis is focused on physico-chemical aspects of microalgal adhesion. The results are based on experimental characterization of surface properties of both microalgae and solids by contact angle and zeta potential measurements. These data were subsequently used in modeling the surface interactions (thermodynamic, classical and extended DLVO models) resulting in quantitative prediction of the interaction intensities. Finally, the model predictions are compared with experimental adhesion tests of microalgae onto model solids in order to identify the physico-chemical forces governing the microalgae-solid interaction. The model solids were prepared in order to cover a wide range of properties (hydrophobicity, surface charge). The results revealed that in low ionic strength environment the adhesion was influenced mostly by electrostatic attraction/repulsion between surfaces, while with increasing ionic strength grew the importance of apolar (hydrophobic) interactions. Among tested materials the highest adhesion of Chlorella vulgaris cells was observed to (3-aminopropyl)triethoxysilane modified glass (APTES glass) mimicking the surface properties of stainless steel. The impact of solid surface properties on the degree of colonization by microlagae was statistically more significant than the influence of culture medium composition on cell surface of Chlorella vulgaris.
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Vodehnal, Michal. "Vývoj tribometru pro měření adheze na reálné kolejnici." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-400935.
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The submitted master’s thesis describes the development of a tribometer used to measure the adhesion of a real rail. The thesis contains an overview of the basic terms concerning wheel and rail contact. Following that, there is an overview of devicesthat are able to measure the adhesion on a real track. The author's solution includes a design of the tribometer, the proposed measurement methodology and also a description of the individual components. The result of this thesis is a functional device, verified in laboratory conditions and on a real track.
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Ibarra, Jonatanh José. "Vliv složení mezivrstvy na pevnost adhezního spoje mezi vláknovým a částicovým kompozitem." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2010. http://www.nusl.cz/ntk/nusl-216635.
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Hlavním cílem této práce je studium aktuálního problému adheze mezi kompozitními materiály, a určení vlivu složení mezivrstvy v pevnosti adhezivního spoje mezi vláknové (FRC) a částicové (PFC) kompozity, používané ve stomatologii. FRC tyčinky byly vytvořené na bázi komerční dimetakrylatové pryskyřice a skleněných S vláken. PFC byl vytvořen ze směsi pryskyřic (bis-GMA a PEGDMA), plněných drceným barnatým sklem. Celkově bylo připraveno a vyzkoušeno 84 vzorků. Vzorky byly rozdělené do pěti hlavních skupin. První skupina byla vytvořena ze série vzorků bez mezivrstvy. Zbylé čtyři skupiny byly rozděleny dle složení mezivrstvy (tloušťky a druhu pryskyřic). Částicové kompozity vzorků se lišily obsahem plniva (0, 10, 40 hm %). FRC tyčinky byly stejné pro všechny vzorky. Univerzální testovací přístroj ZWICK Z010 byl použit k zjištění smykové pevnosti adhezivního spoje všech vzorků. Rastrovací elektronový mikroskop byl použít k pozorování místa porušení. Ze získaných výsledků vyplívá, že s přidáváním mezivrstvy mezi vláknovým a částicovým narůstá smyková pevnost spoje. Důležitost těchto výsledků je způsobená tím, že v posledních letech použití těchto materiálů ve stomatologii narůstá a adheze zůstává jeden z hlavních problémů při klinické praxi.
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Nohel, Rostislav. "Vliv klimatických podmínek na adhezi v kontaktu kola a kolejnice." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-318382.
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Presented master’s thesis is focused on the experimental research of influence of climate conditions on wheel-rail adhesion, where climate conditions are meant two parameters: ambient air temperature and air humidity. These parameters always affect wheel-raid contact and their values change significantly during the year. For presented experimental research was used tribometer Mini Traction Machine (MTM) in configuration „ball on disc“. For determination of influence climate conditions was first found out the influence of air humidity on adhesion at certain temperatures, which varied between (1 to 50) °C. These experiments were performed for two types of discs, where one disc was exposed to leaf extract contamination. After that was assembled influence of both parameters (air humidity and ambient air temperature) on adhesion in the form of a 3D map, where were distinctioned states, when condensation has occured and when didn‘t. Obtained results in this thesis will be used for optimalization of rail vehicle control systems.
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Dobiáš, Jiří. "Studium adheze lepených balistických kompozitů v závislosti na použitých materiálech." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2018. http://www.nusl.cz/ntk/nusl-376803.
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The aim of this work was to investigate the properties of bonded ballistic materialsBalistic composites are mainly glued to reduce weight while keeping their protective properties. On this basis, the materials used were ballistic steel, ceramics, rubber kevlar, non-gummed kevlar, Dyneema and fiberglass. For bonding used were a one-component adhesive Collano 36.104 and two-component adhesive Biresin U1305. The strength of the joint was measured in shear at tensile loads. From these results, deformation energy was further calculated.
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Kejda, Petr. "Konstrukce zkušebního zařízení pro ovlivňování adheze v kontaktu kola s kolejnicí." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-231995.
Full textAbstract:
This thesis aims to design a test equipment for positive change the adhesion contact between the wheel and the rail head. This can be achieved by changing the size of the coefficient of friction, which are eliminated negative effects accompanying the operation of the rail transport (acoustic emissions and excessive wear). Reducing friction must not be compromised traction or braking. Equipment ranks among to Top of Rail systems where as medium is used the friction modifier. The study includes an overview of available types of friction modifiers and applicators Top of rail system. The design of the applicator is built based on the off-board system that is placed in front of the arc track with a small radius of curvature.
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Kozielová, Silvie. "Studium flexibility a adheze cementových lepidel při různém stupni modifikace polymerním pojivem." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2019. http://www.nusl.cz/ntk/nusl-392367.
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The content of the diploma thesis deals with the study of the flexibility and adhesion of cement tile adhesives, which are modified by a polymeric additive. The effects of the quantity and type of redispersible polymer powder used on the properties of the adhesives, in particular on the deformability of adhesives and their adhesion, are monitored. The theoretical part summarizes the basic data concerning classification of the ceramic tiles, information about the adhesives, the processed part concerning the polymer modified adhesives and the effects of the polymeric additives on their properties. The practical part deals primarily with the study of adhesion and flexibility of polymer modified adhesives and study of microstructure of selected materials.
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Galas, Radovan. "Konstrukce experimentálního zařízení pro studium pískování kolejových vozidel." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230586.
Full textAbstract:
Presented master’s thesis describes the design and the implementation of an experimental device used for the study of tribological aspects of wheel-rail contact. In this work, the reader will first learn the fundamentals such as adhesion, slip, traction curve, etc. Subsequently, the work is describing devices that are used for the study of wheel-rail contact around the world. This section is followed by the author proposed solution. The result is a twin disc device in the scale of 1:3. The device allows determining traction characteristics for different environmental conditions (presence of water, sand and oil in contact for different temperatures) and various operating parameters (contact pressure and speed). A part of this work are also the validation experiments and complete design documentation.
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Plichta, Tomáš. "Povrchové a mechanické vlastnosti a-CSi:H a a-CSiO:H vrstev." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2020. http://www.nusl.cz/ntk/nusl-433414.
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The dissertation thesis deals with the preparation and characterisation of a-CSi:H and a CSiO:H thin films prepared using the process of plasma enhanced chemical vapour deposition (PECVD). Tetravinylsilane (TVS) and its mixtures with argon and oxygen were used to deposit films on both planar substrates and fibre bundles. Main characterisation techniques were employed to study the topography of films, namely atomic force microscopy (AFM). Their mechanical properties were studied through nanoindentation; the nanoscratch test was used to assess the film adhesion to the substrate. Other analysed properties were internal stress and friction coefficient. The particular attention was paid to the work of adhesion and its determination. This knowledge was further applied to the preparation of surface treatments of glass fibres and, subsequently, polymer composites. Those were tested using the push-out test and the short beam shear test. Based on the results, the effects of deposition conditions and the relationships between the studied properties and quantities were determined.
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Habrová, Karolína. "Vlastnosti lepených spojů plněných mikročásticovým plnivem." Master's thesis, Česká zemědělská univerzita v Praze, 2016. http://www.nusl.cz/ntk/nusl-256971.
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This thesis deals with the measuring of adhesive and cohesive characteristics of composite systems filled with microparticles of glass powder.
The theoretical part describes in detail composites from their historical development
to the present, also their characteristics, general properties, distribution and types of fibers
and matrices. Emphasis is placed on composites filled with particulate filler and current researches in the field of composites with glass filler. Furthermore, the adhesion and cohesion of filled systems is described.
The experimental part of this thesis includes a methodology, which describes in detail
the used materials, methods of preparation of mechanical testing and statistical analysis. The results of mechanical tests for all three composite mixtures and evaluation of cost savings are appended to this thesis.
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Matiash, Dmytro. "Opravy kontaktních ploch součástí pomocí technologie studené kinetizace." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-416612.
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The aim of this master’s thesis was to evaluate cold spray technologies as an alternative method of repairing contact surfaces of parts, especially made of high-alloy manganese steels, to choose a suitable system of materials and to analyze the properties and structure of the produced coating. The thesis presents the basic of the mechanism of cold spray deposition, the described influence of basic process parameters on the structure and properties of metal coatings. Performed analysis of chemical composition, structure, porosity, hardness and strength of AISI H13 steel coating on a high-alloy manganese steel substrate. The described dependence of the structure and properties of a given coating on the heat treatment regime.
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Panáček, Vladimír. "Problematika znalecké analýzy jízdy a brzdění vozidla v obecném prostorovém oblouku při rychlostech vyšších než 50 km/h." Doctoral thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-234324.
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The present apparatus for the technical analysis of road accidents has no well-integrated information, recommendations or procedures of how to solve comprehensively the analysis of road accidents involving vehicles equipped with stabilization system of driving dynamics. The problem in the investigation of a vehicle movement in a curve is the ignorance of the contributions of vehicle dynamics intervention of the electronic stability system. Although some of the simulation software used in the analysis of road accidents makes it possible to take into account the modelled vehicle movement impacted by a stabilization system in the examined process, but the experts do not know what parameters should be entered in the numerical models of stabilization system in a computer programme. Therefore, the thesis investigates the issue of the expert analysis of vehicle riding and braking in a general spatial curve at speeds exceeding 50 kph with simultaneous examining the impact of electronic stability system chassis on vehicle driving dynamics. The thesis first deals with the solutions based on classical analytical methods, then dwells on experimental measurements in real conditions on testing grounds and, finally, addresses the use of computer simulation software in expert practice. Nevertheless, it is important to realize that no computer simulation software can be an absolutely unambiguous solver, and it is not enough to generate a computer simulation, but so obtained results should be evaluated and justified technically. Road accident analyst needs to know the impact of vehicle electronic stability control systems on vehicle movement. The thesis investigated the mutual relationship between the vehicle speed limit in a curve specified by analytical calculation and the vehicle speed in a curve experimentally detected by measuring the parameters of driving dynamics of a vehicle equipped with electronic stability system. The impact of selected electronic stability control systems of the chassis on the vehicle movement in the investigated processes in the curve was detected and quantified by driving experiments. Finally, the input values of significant quantities of computational models of the ESP simulation programs were found consistent with the results of experimental measurements in defined curves for the vehicles equipped with electronic stability systems. The results of the thesis can be used both in the expert and in the teaching activities.
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Krvač, Matěj. "Opravy vysokopevnostních ocelí pomocí technologie studené kinetizace." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-432550.
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This diploma thesis takes into account the possibility of repairing high-strength steels using coldspray method. The theoretical part is focused on the coldspray method, austenite transformation, bainitic steels and Rmat contact fatigue tests. In the experimental part evaluate the hardness, the structure of the supplied substrate. The hardness, adhesion and porosity of the test sprays are ranked. Furthermore, tests for contact fatigue are evaluated. Finally, the results of the experiments are summarized and measures are proposed to improve adhesion, or to continue this issue.
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Poláková, Kateřina. "Studium chování buněk na nanostrukturovaných TiO2 površích." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2016. http://www.nusl.cz/ntk/nusl-242098.
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This thesis deals with the study of cells on nanostructured surfaces of titanium dioxide, which are produced by the electrochemical method called anodic oxidation. The theoretical part is formed by an overview of manufacturing nanostructured surfaces using anodic oxidation method. It mentions the influence of external factors on the geometric parameters of the structure and description of methods of characterization structures. Furthermore there is processed outline of use for biomedical application and the description of interaction of the cell with surface. The practical part includes description of the production of nanoporous and nano-tubular structures made on thin films of titanium by direct method of anodic oxidation on which was studied the influence of external factors. Described a procedure and production of nanorods structures and nanodots generated using alumina template (AAO) which is subsequently carried out the study of the behavior of cells, which includes tests of adhesion, examination of morphology of cells, assays of proliferation and differentiation. Structures are under investigation of the interaction of cells with the nanostructured layer compared with the smooth surface of the titanium dioxide.
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Dušek, Otakar. "Vliv hmotnostních parametrů vozidel na jízdní dynamiku." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2016. http://www.nusl.cz/ntk/nusl-241368.
Full textAbstract:
This diploma thesis deals with assessment of weight parameters impact on driving dynamics. History and basic categories of personal vehicles are described in the introductory part. Weight parameters and driving dynamics of personal vehicles are described in the next part. Methodology and results of realized driving tests (braking test, circular test and avoidance maneuver) are presented in the experimental part of this work. Simulation of realized driving tests that was made by simulation software Virtual Crash is devised in the penultimate chapter. Evaluation of results that were found out from realized and simulated driving tests is made in the last chapter. Achieved results are briefly summarized in conclusion.
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Budzik, Michal. "Fracture in asymmetric bonded joints." Thesis, Bordeaux 1, 2010. http://www.theses.fr/2010BOR14041/document.
Full textAbstract:
Des tests de fissuration ont été réalisés sur des joints collés asymétriques. Ces assemblages asymétriques sont constitués de deux substrats de nature et/ou d’épaisseur différentes liés par un adhésif. Cette géométrie d’éprouvette semble peu utilisée pour effectuer des essais de fissuration. Elles présentent certains inconvénients et de ce fait n’ont fait l’objet d’aucune normalisation. Dans le cadre cette géométrie d’éprouvette d’essai a été néanmoins été retenue et utilisée dans trois configurations différentes pour la caractérisation mécanique des assemblages collés. Des protocoles d’essai et les schéma d’analyse associés ont été définis pour des essais de fissuration à vitesse de déplacement imposé (CRT : Constant Rate Test), à force imposée (CFT : Constant Force Test) ainsi qu’à déplacement imposé (CDT : Constant Displacement Test). Les analyses ont pu être étalonnées au moyen d’un étau matérialisant artificiellement la position d’un fissure. De nombreuses configurations ont été étudiées à l’occasion de ce travail tant du point de vue des adhésifs utilisés (epoxy, cyanoacrylate, acrylic mastic, PSA) que du point de vue des substrats encollés (alliage d’aluminium, composite à matrice organique, polycarbonate). Ces nouveaux tests s’avèrent prometteurs car ils permettent de suivre de façon continu et précision la propagation de fissure au sein de la liaison. En outre, l’analyse des déformations mesurées par extensométrie lors d’essai réalisés à déplacement imposé (CDT) permet un suivi précis de la réponse de la couche adhésive dans la zone contrainte et d’estimer la taille de cette dernière, y compris lorsque la colle est dans un état métastable. Un autre résultat important de ce travail concerne l’analyse de la modification du front de fissure celle-ci voit une diminution de l’adhésion entre les deux substrats. Enfin, un calcul plus précis du taux de restitution d’énergie a été proposé pour prendre en compte le caractère élastique de la couche adhésive, mais permettant aussi de mieux appréhender la redistribution des contraintes dans la colle, et ainsi mieux interpréter les essais mécaniques réalisés. Des analyses par Microscopie à Force Atomique (AFM) ainsi qu’au microscope électronique à balayage (MEB) ont été effectués sur les substrats encollés pour évaluer l’impact des traitements de surface. Des simulations numériques par la method des éléments finis ont été réalisées pour determiner l’état de contrainte dans nos éprouvette d’essai et ainsi expliquer la courbure du front de fissure et les faciès de rupture observés. Les nouvelles configurations expérimentales décrites dans ce manuscript nous paraissent prometteuses car elle offrent une amelioration très significative en terme de fiabilité et précision comparativement aux tests présentés habituellement pour ce type de travauxAdhesion was studied in asymmetric bonded joints using fracture mechanics tests. The asymmetric bonded joints consist of two different type and/or thickness materials bonded by an adhesive. Mentions of asymmetric bonded joint tests employed so far are rare in the literature. They are imperfect and therefore are not standardized. Accordingly three new tests were introduced in this work to study bonded joints. The new metrological routines and models were built for the CRT (Constant Rate Test), CFT (Constant Force Test) and the CDT (Constant Displacement Test). The routines were validated with the new Artificial Crack Tip test developed in this thesis. Different bonded systems were examined: the adhesives - epoxy, cyanoacrylate, acrylic mastic, PSA; the bonded adherends - aluminium alloys, CFRP composites and polycarbonate. The results obtained in the new tests are very promising in terms of the accuracy and continuous observation of crack kinetics. In addition it was found that the novel strain gauge technique, introduced in the CDT, test allows precise joint monitoring when the adhesive is in a metastable state and a precise estimation of process zone. Another interesting achievement of this work was describing the phenomenon of double crack curvature in the vicinity of the strong – weak adhesion transition zone. The next achievement was derivation of the strain energy release rate from the elastic foundation model, which gives better understanding of the mechanics and the measurements behind adhesive bonding. Atomic Force Microscope (AFM) and Scanning Electron Microscope (SEM) studies were made of the bonded substrates to estimate the surface treatment effects. The stress state in asymmetric geometry was studied using finite element analysis (FEA), which explained the formation of the curved crack front and the origin of river patterns. The new tests developed in this study appear promising since they offer accurate and reliable results for the materials tested
W pracy przedstawiono wyniki badan asymetrycznych zlaczy adhezyjnych z wykorzystaniem prób mechaniki pekania. Asymetryczne zlacza klejone powstaja przez polaczenie dwóch dowolnych materialów, o innym wskazniku na zginanie, za pomoca kleju. Zaproponowano trzy nowe metody eksperymentalne dla których zaprojektowano i zbudowano stanowiska badawcze. Poprawnosc modeli fizycznych i matematycznych wykorzystanych do interpretacji badanych zjawisk potwierdzono wykorzystujac opracowana w pracy próbe ze sztucznym frontem pekniecia. Próby przeprowadzono na zlaczach klejonych wykorzystujac kleje: epoksydowe, cjanoakrylowy, typu Mastic i PSA, laczonymi materialami byly: stopy aluminium, kompozyt weglowy oraz poliweglan. Wyniki badan uzyskane przy wykorzystaniu nowych metod wskazuja na ich pewnosc i dokladnosc, dodatkowo umozliwiaja ciagla obserwacje propagujacego pekniecia. Nowa metoda pomiaru parametrów mechaniki pekania oparta na pomiarach tensometrycznych zostala z powodzeniem zastosowana do zlaczy w których klej znajduje sie w stanie metastabilnym. W pracy zaobserwowano i przeanalizowano zjawisko powstawania podwójnego frontu pekniecia na granicy osrodków o róznych silach adhezji, dotad nie opisanego. Po raz pierwszy wyprowadzono równanie szybkosci uwalniania energii sprezystej wykorzystujac model belki na sprezystym podlozu, co umozliwia lepsze zrozumienie zachowania sie zlaczy klejonych. Przeprowadzone badania z uzyciem mikroskopii sil atomowych (AFM) oraz skaningowej mikroskopii elektronowej (SEM) umozliwily ocene efektów obróbki powierzchniowej stopów aluminium. W pracy dokonano analizy naprezen w asymetrycznych zlaczach adhezyjnych z wykorzystaniem metody elementów skonczonych (FEM). Analiza FEM pozwolila na wyjasnienie zjawiska powstawania zakrzywionego frontu pekniecia w badanych przelomach. Zaproponowane nowe metody badan zlaczy asymetrycznych zapewniaja dokladnosc i pewnosc pomiaru dla materialów wykorzystanych w badaniach
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Trhoň, Vojtěch. "Vliv povrchu na pevnost lepeného spoje." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229658.
Full textAbstract:
This master’s thesis is divided into two parts. In the first part are these topics: bonding theory, treatment of bonding surface, types of adhesives, adhesives in the transportation industry and construction and stress of bonded joints. In the second part of this thesis is experimental evaluation of the effect of surface of material on strength of bonded joint.
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Janeček, Pavel. "Vliv povrchových úprav skleněných vláken na mechanickou odezvu GF/polyester kompozitu." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2008. http://www.nusl.cz/ntk/nusl-216224.
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The diploma thesis is aimed at an influence of surface modifications of fibrous reinforcements on mechanical properties at the fiber-matrix interface in fiber reinforced composites. Glass fibers were used as reinforcements and polyester resin was the matrix. The sample of composite consisted of polymer matrix in a form of cylindrical body placed on bundle of glass fibers. The design of the sample was constructed with respect to results of Finite Element Analysis (FEA). The tensile test using a materials testing machine (Zwick) was employed to evaluate adhesion at the fiber-matrix interface. Untreated glass fibers, fibers with commercial sizing, and fibers modified by deposition of plasma polymer film using Plasma-Enhanced Chemical Vapor Deposition (PECVD) at different deposition conditions were used for fabrication of composite samples. The fibers and composite samples were analyzed by Scanning Electron Microscopy (SEM) and Confocal Laser Scanning Microscopy (CLSM).
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Skurka, Šimon. "Vývoj maziva pro temeno kolejnice." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2021. http://www.nusl.cz/ntk/nusl-443457.
Full textAbstract:
Friction modification within the wheel-rail interface is an important way of achieving ecologically friendly transportation of both persons and goods. This thesis aims to develop a new TOR lubricant, which will be able to maintain suitable frictional conditions while securing minimal adhesion required for traction. All measurements were carried out on tribometer MTM in the ball-on-disc configuration. In the first step, individual components were examined. More complex compositions were measured after that and the three best of them were compared with commercial TOR lubricants. The results show a good ability of developed compositions to maintain required adhesion, reduce wear, and all of them had resistivity against over-lubrication. Lastly, the process of lubricant verification before its application in real traffic was discussed.
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Sedlák, Filip. "Povrchové úpravy skleněných vláken s využitím plazmové nanotechnologie." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-295727.
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Diploma thesis is aimed at deposition of thin films on glass fibers using plasma-enhanced chemical vapor deposition from tetravinylsilane as a monomer. Such surface modified glass fibers were used as reinforcements for fabrication of polymer composites with unsaturated polyester resin as a matrix. Chemical and optical properties of prepared thin films were characterized using infared spectroscopy and spectroscopic ellipsometry. An influence of deposited thin films on the shear strength of composite material was observed using short-beam shear test.
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Bílek, Ondřej. "Příprava a charakterizace TiO2 nanotrubiček dekorovaných stříbrem pro biomedicínské účely." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2017. http://www.nusl.cz/ntk/nusl-316823.
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This diploma thesis summarizes knowledge from the fields of synthesis, characterization and application of titanium dioxide nanotubes and its combination with silver nanoparticles for biomedical purposes. Basic protocols of working with cell cultures and bacteria are also included. Experimental part of this diploma thesis focuses mainly on the synthesis of tubular structures made of titanium dioxide via anodic oxidation of 500nm titanium layer and their subsequent decoration with silver by electrodeposition. Last section of the experimental part is devoted to testing of antibacterial properties of the new material and examining the effect of different silver concentrations on the adhesion of MG-63 cells. All results are compared to reference samples consisting of titanium dioxide nanotubes without silver.
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Pospíšek, Marek. "Chemické modifikace polypropylénových povrchů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2014. http://www.nusl.cz/ntk/nusl-217038.
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Diploma thesis is focused on modification and characterization of polypropylene (PP) products surfaces by the chemical way. In theoretical part of thesis are summarized the current knowledge of this topic including characterization methods. Polypropylene surfaces were modified by acrylic monomers (acrylic acid, acrylic acid with 20 mol% content of sodium acrylate and acryl amide). Modified surfaces were characterized by infrared spectroscopy with ATR technique. The comparative parameter was carbonyl index determined from absorption peaks of functional methyl groups (2950 cm-1 ) and functional carbonyl groups (1700-1750 cm-1) of FTIR-ATR spectra. Determination of effect of initiator concentration on the modification process was done for acetophenone and benzophenone. There were determined the time dependence of carbonyl index for time from 0 to 600 s of mentioned monomers. In the same condition were modified test specimens designed for preparation of adhesive joints. Joints were bonded by cyanoacrylate adhesive that provide reaction with surface of polyacrylic acid. There were founded conditions of modification that provided strength of adhesive joints higher than strength of original PP. There were identified changes of surface roughness by using of confocal microscopy.
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Beranová, Andrea. "Adhezní řízení." Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-351514.
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The doctoral thesis focuses on the part of criminal proceedings in which the court adjudicates the injured person's private claims which arose in connection with a criminal act (so-called collateral proceedings). The importance of collateral proceedings lies in the fact that by using it the injured party may avoid time-consuming, financially as well as procedurally demanding civil proceedings. However, the institute of collateral proceedings comprises a number of specific issues since a criminal court adjudicates the private claims of the injured party in compliance with substantive law rules being outside of the scope of criminal law (mainly civil law and labour law regulations) but, still, within the framework of criminal proceedings. The basic source of the submitted thesis is the Czech legal order. However, it is not the only one taken into consideration. The doctoral thesis also contains comparative analysis of legal regulation of collateral proceedings from the point of view of the German and Swiss legal orders. Following the analysis of collateral proceedings de lege lata, as well as the comparison with foreign models I am submitting proposals for the improvement of legislation that could be used in connection with the planned recodification of the Czech Criminal Procedure.
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Pospíšilová, Naďa. "Adhezní molekuly a jejich úloha v modelových patologických stavech." Doctoral thesis, 2009. http://www.nusl.cz/ntk/nusl-278454.
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Souhrn/Summary 1 Atherosclerosis is one of the major causes of cardiovascular morbidity. This chronic inflammatory disease is characterized by endothelial dysfunction with accumulation of lipids, leukocytes, smooth muscle cells and extracellular matrix within the vessel intima. This process results in reducing of the vessel lumen that can lead to the obstruction of vessel blood flow. The initiation of atherogenic process is characterized by the alteration of endothelial function which is so-called endothelial dysfunction. The endothelial dysfunction is characterized by the expression of cell adhesion molecules and increased endothelial permeability for monocytes, T-cells and lipoproteins. This is beginning of "vicious"circle of atherosclerosis. On of the most important cell adhesion molecules participating in the beginning of atherogenesis are members of the immunoglobulin superfamily, VCAM-1 (vascular cell adhesion molekule-1), ICAM-1 (intracellular cell adhesion molekule-1) and PECAM-1 (platelet-endothelial cell adhesion molekule-1).VCAM-1 and ICAM-1 are transmembrane glycoproteins participacing predominantly in the stabilization leukocyte of interaction with endothelium and transmigration of leukocytes into vessel intima. In this dissertation thesis, the first studies were focused on the endothelial...
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Obr, Adam. "Adhezní struktury leukemických buněk a jejich regulace kinázami rodiny Src." Doctoral thesis, 2018. http://www.nusl.cz/ntk/nusl-383824.
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Adhesion signaling is a field of cell biology studied mostly on adherent cell types. However, hematopoietic cells grow in suspension, and use adhesion to the extracellular matrix (ECM) only in their early development, or - in case of differentiated cells - to perform the tasks they are specialized for. Peripheral leukemic cells are derived from more or less immature hematopoietic precursors that have, among other alterations, defects in adhesion to the bone marrow microenvironment. On the other hand, leukemic stem cells (LSC) use adhesion to the bone marrow ECM as a mean to evade chemotherapy, and are a source of the minimal residual disease, and of the disease relapses. Kinases of the Src family (SFK) are known regulators of adhesion signaling in adherent cell types, and their overexpression and/or hyperactivation is often seen in malignant diseases. They are also involved in hematooncologic disease progression and resistance to therapy, particularly in several types of leukemias. In the present work, we used a variety of methods including microimpedance measurement, fluorimetric measurement of adhered cell fraction, immunoblotting, confocal microscopy, and interference reflection microscopy. Our results indicate that active Lyn kinase, a hematopoietic SFK, is present in adhesion structures of...
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Obr, Adam. "Analýza vlivu inhibitorů Src kináz na adhezní signalizaci v lidských hematopoietických buňkách." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-310544.
Full textAbstract:
Adhesion of hematopoietic cells to the bone marrow microenvironment is important for their proper development. It is proven that Src-family kinases (SFK) regulate cell adhesion, although their exact role in the regulation of adhesion signaling remains unclear. Since adhesion processes are investigated mainly in adherent cell types, far less is known about hematopoietic cells. However, defects in the cell adhesion accompany a number of hematological diseases, like chronic myeloid leukaemia (CML). SFK overexpression is one of the proposed mechanisms of resistance to the first-line CML treatment, imatinib mesylate. Second generation drugs (e. g. dasatinib) inhibit SFK together with Bcr-Abl. Additionally, SFK-specific inhibitors (PP2, Src inhibitor-1) are also available, but there are no studies about effects of these drugs on cellular adhesivity of hematopoietic precursors. To explore the dynamics of hematopoietic cell adhesion to the extracellular matrix, we introduced a new approach using the RTCA xCELLigence DP system along with the well-established method of fluorimetric detection of adherent cell fraction. Our general observation is that various drugs (dasatinib, imatinib, PP2, Src inhibitor-1) induce pro-adhesive effects in several leukemic cell lines. Direct comparison of the kinetics of...
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Hlůže, David. "Uzavírání adhezních smluv podnikatelem." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-437856.
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Conclusion of adhesion contracts by entrepreneurs Abstract The aim of this work is to describe the conditions under which the protective provisions of the Civil Code on the conclusion of contracts in an adhesive manner are applied in relations where the entrepreneur acts. In this regard, attention is focused on the definition of the weaker party and the individual conditions that the entrepreneur must meet if he is to enjoy the protection of the weaker party. Subsequently, the work deals with the institute of concluding contracts in an adhesive manner, formulating its individual features and manifestations, especially in commercial practice. This work consists of an introduction, four chapters and a conclusion. The first chapter forms the basis for the rest of this work, by defining the weaker party with an emphasis on relations between entrepreneurs. Furthermore, this form describes the form of protection of the weaker party with an analysis of private and public protection of the weaker entrepreneur. The second chapter deals with contracts concluded in an adhesive manner and burden of proof beard by the contracting party. Subsequently, this work captures the most common forms in contractual practice such as general terms and conditions, form documents or framework contracts. A specific form of adhesion...
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Dolejšová, Tereza. "Náhrada nemajetkové újmy při ublížení na zdraví a usmrcení v adhezním řízení." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-435512.
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1 Abstract Compensation for non-pecuniary harm in the event of personal injury and death in collateral proceedings The topic of the diploma thesis is the issue of compensation for non-pecuniary harm in the event of personal injury and death in collateral proceedings. This issue is currently often debated due to, among other reasons, a change in the legal regulation of compensation for pecuniary and non-pecuniary harm effective from January 1, 2014. The specificity of this subject lies in the combination of two legal branches - criminal and civil law, as collateral proceedings are part of criminal proceedings and decide on claims which are of a civil nature. The thesis deals with the criminal law institutes of the injured party and the collateral proceedings themselves. An extensive space is then devoted to the private law regulation of compensation for non-pecuniary harm in the event of personal injury and death, especially in accordance with Sections 2958 and 2959 of the Civil Code with regard to legal practice and court decisions. The aim of this work is to describe and evaluate the legal regulation of compensation for non-pecuniary harm in the event of personal injury and death and the procedural possibilities of the injured party to attain this private law claim in criminal proceedings. With regard to...
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Ceplová, Magdalena. "Aktuální otázky adhezního řízení." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-411556.
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Current issues of adhesive proceedings This thesis deals with current issues of adhesive proceedings. The thesis is divided into four chapters. The first chapter introduces the basic concepts essential for the definition of adhesive proceedings and related terms. These are primarily the definition of entities and parties to criminal proceedings, including the introduction of the institutes of harm as an overarching term, which includes damage, non-material damages and unjust enrichment. The first chapter also introduces the institute of bodily harm. The second chapter is devoted to the injured party, including a list of procedural rights and obligations that the injured party confers the Criminal Procedure Code and the injured party recognizes the law on victims of crime, if the injured party is also a victim under this law. The following subchapters are divided according to the rights that belong to all the injured parties and the rights that belong to the injured party, who is at the same time subject to the adhesive procedure. In the case of the injured party, the institute of consent of the injured party to criminal prosecution and representation of the injured party is also mentioned. In this part of the thesis, the current problems concerning the remuneration of the injured party's...
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Doležalová, Gabriela. "Náhrada nemajetkové újmy na zdraví a rozhodování o ní v adhezním (trestním) řízení." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-405705.
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Non-material damage in health injury and decision making in adhesive (criminal) proceedings Abstract The diploma thesis focuses on current legislature, issues and questions regarding compensation of non-material damage (non- property harm), specifically health injuries in adhesive proceedings. The topic presented hereby is a relatively young field of interest in the Czech law system, moreover it has gone through relatively dynamic development recently. The topic of the diploma thesis is effectively linking criminal, civil and health (medical / health care) law. The diploma thesis presents an outlook on the concept of non-material damages from the point of view of civil law and outlines the concepts of injured party and adhesive proceedings belonging to the criminal law field. The diploma theses presents an insight into the terms of liability and criminal liability and it also briefly concerns the criminal liability in health care. The diploma thesis presents some of the selected criminal offences (crimes) against human life and health. The diploma thesis also focuses on terms and proceedings of the adhesive (criminal) proceedings and the possibilities and rights of injured party in the proceedings. The diploma theses presents differences and common points of the terms "injured party" and "victim" in the...
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Sýkora, Jiří. "Náhrada nemajetkové újmy při ublížení na zdraví a usmrcení v adhezním řízení." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-396153.
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Compensation for non-material damage in the event of injury and death in collateral proceedings Abstract The thesis deals with a very current topic of compensation for non-material damage in the event of injury and death in collateral proceedings. The thesis also contains chapters, that focus on an injured person and collateral proceedings, which are concepts directly connected to the main topic of the thesis. The thesis contains the definition of an injured person, rights and obligations of the injured person in the criminal proceedings and also the definition of collateral proceedings and its process. In particular, the thesis focuses on the compensation of non-material damage in the event of injury and death according to § 2958 and 2959 of the Civil code. The thesis also describes the current judicial decisions of criminal courts in the area of compensation for non-material damage in the event of injury and death in collateral proceedings. The thesis is composed of four parts. The first part of the thesis deals with the injured person. It contains the concept of an injured person and its legal definition. The rights and obligations of the injured party in criminal proceedings are also briefly described in this part. The second part of the thesis focuses on collateral proceedings. This part contains the...