Journal articles on the topic 'Adeno-Associated Viral (AAV) vectors'
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Bartlett, Jeffrey S., Rose Wilcher, and R. Jude Samulski. "Infectious Entry Pathway of Adeno-Associated Virus and Adeno-Associated Virus Vectors." Journal of Virology 74, no. 6 (March 15, 2000): 2777–85. http://dx.doi.org/10.1128/jvi.74.6.2777-2785.2000.
Full textLieber, André, Dirk S. Steinwaerder, Cheryl A. Carlson, and Mark A. Kay. "Integrating Adenovirus–Adeno-Associated Virus Hybrid Vectors Devoid of All Viral Genes." Journal of Virology 73, no. 11 (November 1, 1999): 9314–24. http://dx.doi.org/10.1128/jvi.73.11.9314-9324.1999.
Full textXuan, Keh Min, Nur Ain Mohd Asri, Rafeah Suppian, Norazmi Mohd Nor, Maryam Azlan, and Frank Camacho. "The Use of Adeno-associated virus (AAV) in Vaccine Development." Asian Journal of Medicine and Biomedicine 6, S1 (November 10, 2022): 192–93. http://dx.doi.org/10.37231/ajmb.2022.6.s1.583.
Full textGonçalves, Manuel A. F. V., Ietje van der Velde, Josephine M. Janssen, Bram T. H. Maassen, Evert H. Heemskerk, Dirk-Jan E. Opstelten, Shoshan Knaän-Shanzer, Dinko Valerio, and Antoine A. F. de Vries. "Efficient Generation and Amplification of High-Capacity Adeno-Associated Virus/Adenovirus Hybrid Vectors." Journal of Virology 76, no. 21 (November 1, 2002): 10734–44. http://dx.doi.org/10.1128/jvi.76.21.10734-10744.2002.
Full textFavaro, Patricia, Harre D. Downey, Federico Mingozzi, Fraser Wright, Bernd Hauck, Katherine A. High, and Valder R. Arruda. "Safety of Recombinant Adeno-Associated Viral Vectors in a Large Animal Model." Blood 110, no. 11 (November 16, 2007): 2586. http://dx.doi.org/10.1182/blood.v110.11.2586.2586.
Full textYan, Ziying, Roman Zak, Yulong Zhang, and John F. Engelhardt. "Inverted Terminal Repeat Sequences Are Important for Intermolecular Recombination and Circularization of Adeno-Associated Virus Genomes." Journal of Virology 79, no. 1 (January 1, 2005): 364–79. http://dx.doi.org/10.1128/jvi.79.1.364-379.2005.
Full textMingozzi, Federico, Jörg Schüttrumpf, Valder R. Arruda, Yuhong Liu, Yi-Lin Liu, Katherine A. High, Weidong Xiao, and Roland W. Herzog. "Improved Hepatic Gene Transfer by Using an Adeno-Associated Virus Serotype 5 Vector." Journal of Virology 76, no. 20 (October 15, 2002): 10497–502. http://dx.doi.org/10.1128/jvi.76.20.10497-10502.2002.
Full textHanazono, Yutaka, Kevin E. Brown, Atsushi Handa, Mark E. Metzger, Dominik Heim, Gary J. Kurtzman, Robert E. Donahue, and Cynthia E. Dunbar. "In Vivo Marking of Rhesus Monkey Lymphocytes by Adeno-Associated Viral Vectors: Direct Comparison With Retroviral Vectors." Blood 94, no. 7 (October 1, 1999): 2263–70. http://dx.doi.org/10.1182/blood.v94.7.2263.419k36_2263_2270.
Full textJewell, Andrew P., Melanie Cochrane, Jenny McIntosh, Reuben Benjamin, and Amit Nathwani. "Comparison of Viral Vectors for Gene Transfer into CLL Cells: Efficient Transduction with Adeno-Associated Virus-8 (AAV-8)." Blood 106, no. 11 (November 16, 2005): 2985. http://dx.doi.org/10.1182/blood.v106.11.2985.2985.
Full textMonahan, Paul E., Claude Négrier, Michael Tarantino, Leonard A. Valentino, and Federico Mingozzi. "Emerging Immunogenicity and Genotoxicity Considerations of Adeno-Associated Virus Vector Gene Therapy for Hemophilia." Journal of Clinical Medicine 10, no. 11 (June 2, 2021): 2471. http://dx.doi.org/10.3390/jcm10112471.
Full textGrimm, Dirk, Shangzhen Zhou, Hiroyuki Nakai, Clare E. Thomas, Theresa A. Storm, Sally Fuess, Takashi Matsushita, et al. "Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy." Blood 102, no. 7 (October 1, 2003): 2412–19. http://dx.doi.org/10.1182/blood-2003-02-0495.
Full textRICHTER, MATTHIAS, AKIKO IWATA, JOHN NYHUIS, YOSHIO NITTA, A. DUSTY MILLER, CHRISTINE L. HALBERT, and MARGARET D. ALLEN. "Adeno-associated virus vector transduction of vascular smooth muscle cells in vivo." Physiological Genomics 2, no. 3 (April 27, 2000): 117–27. http://dx.doi.org/10.1152/physiolgenomics.2000.2.3.117.
Full textMiller, Daniel G., Grant D. Trobridge, Lisa M. Petek, Michael A. Jacobs, Rajinder Kaul, and David W. Russell. "Large-Scale Analysis of Adeno-Associated Virus Vector Integration Sites in Normal Human Cells." Journal of Virology 79, no. 17 (September 1, 2005): 11434–42. http://dx.doi.org/10.1128/jvi.79.17.11434-11442.2005.
Full textTickner, Zachary J., and Michael Farzan. "Riboswitches for Controlled Expression of Therapeutic Transgenes Delivered by Adeno-Associated Viral Vectors." Pharmaceuticals 14, no. 6 (June 10, 2021): 554. http://dx.doi.org/10.3390/ph14060554.
Full textDuan, Dongsheng, Qiang Li, Aimee W. Kao, Yongping Yue, Jeffrey E. Pessin, and John F. Engelhardt. "Dynamin Is Required for Recombinant Adeno-Associated Virus Type 2 Infection." Journal of Virology 73, no. 12 (December 1, 1999): 10371–76. http://dx.doi.org/10.1128/jvi.73.12.10371-10376.1999.
Full textTrapani. "Adeno-Associated Viral Vectors as a Tool for Large Gene Delivery to the Retina." Genes 10, no. 4 (April 9, 2019): 287. http://dx.doi.org/10.3390/genes10040287.
Full textGrimm, Dirk, Joyce S. Lee, Lora Wang, Tushar Desai, Bassel Akache, Theresa A. Storm, and Mark A. Kay. "In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses." Journal of Virology 82, no. 12 (April 9, 2008): 5887–911. http://dx.doi.org/10.1128/jvi.00254-08.
Full textXiao, Xiao, Juan Li, and Richard Jude Samulski. "Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus." Journal of Virology 72, no. 3 (March 1, 1998): 2224–32. http://dx.doi.org/10.1128/jvi.72.3.2224-2232.1998.
Full textShayakhmetov, Dmitry M., Cheryl A. Carlson, Hartmut Stecher, Qiliang Li, George Stamatoyannopoulos, and André Lieber. "A High-Capacity, Capsid-Modified Hybrid Adenovirus/Adeno-Associated Virus Vector for Stable Transduction of Human Hematopoietic Cells." Journal of Virology 76, no. 3 (February 1, 2002): 1135–43. http://dx.doi.org/10.1128/jvi.76.3.1135-1143.2002.
Full textHauck, Bernd, Wei Zhao, Katherine High, and Weidong Xiao. "Intracellular Viral Processing, Not Single-Stranded DNA Accumulation, Is Crucial for Recombinant Adeno-Associated Virus Transduction." Journal of Virology 78, no. 24 (December 15, 2004): 13678–86. http://dx.doi.org/10.1128/jvi.78.24.13678-13686.2004.
Full textSellner, Leopold, Marlon R. Veldwijk, Jürgen A. Kleinschmidt, Stephanie Laufs, Julian Topaly, W. Jens Zeller, Frederik Wenz, and Stefan Fruehauf. "Gene Therapy of Chronic Myelogenous Leukemia Using Pseudotyped Recombinant Adeno-Associated Viral Vectors." Blood 114, no. 22 (November 20, 2009): 4506. http://dx.doi.org/10.1182/blood.v114.22.4506.4506.
Full textVeldwijk, Marlon R., Leopold Sellner, Marius Stiefelhagen, Jürgen A. Kleinschmidt, Stephanie Laufs, Julian Topaly, Frederik Wenz, W. Jens Zeller, and Stefan Fruehauf. "Novel Efficient Primary Human Peripheral Blood Progenitor Cell-Targeted Recombinant Adeno-Associated Viral Vectors." Blood 110, no. 11 (November 16, 2007): 5144. http://dx.doi.org/10.1182/blood.v110.11.5144.5144.
Full textHansen, Jonathan, Keyun Qing, and Arun Srivastava. "Adeno-Associated Virus Type 2-Mediated Gene Transfer: Altered Endocytic Processing Enhances Transduction Efficiency in Murine Fibroblasts." Journal of Virology 75, no. 9 (May 1, 2001): 4080–90. http://dx.doi.org/10.1128/jvi.75.9.4080-4090.2001.
Full textGao, Guangping, Luk H. Vandenberghe, Mauricio R. Alvira, You Lu, Roberto Calcedo, Xiangyang Zhou, and James M. Wilson. "Clades of Adeno-Associated Viruses Are Widely Disseminated in Human Tissues." Journal of Virology 78, no. 12 (June 15, 2004): 6381–88. http://dx.doi.org/10.1128/jvi.78.12.6381-6388.2004.
Full textMano, Miguel, Rudy Ippodrino, Lorena Zentilin, Serena Zacchigna, and Mauro Giacca. "Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction." Proceedings of the National Academy of Sciences 112, no. 36 (August 24, 2015): 11276–81. http://dx.doi.org/10.1073/pnas.1503607112.
Full textWang, Xu-Shan, Benjawan Khuntirat, Keyun Qing, Selvarangan Ponnazhagan, Dagmar M. Kube, Shangzhen Zhou, Varavani J. Dwarki, and Arun Srivastava. "Characterization of Wild-Type Adeno-Associated Virus Type 2-Like Particles Generated during Recombinant Viral Vector Production and Strategies for Their Elimination." Journal of Virology 72, no. 7 (July 1, 1998): 5472–80. http://dx.doi.org/10.1128/jvi.72.7.5472-5480.1998.
Full textChoi, Vivian W., Douglas M. McCarty, and R. Jude Samulski. "Host Cell DNA Repair Pathways in Adeno-Associated Viral Genome Processing." Journal of Virology 80, no. 21 (November 1, 2006): 10346–56. http://dx.doi.org/10.1128/jvi.00841-06.
Full textMendoza, Skyler D., Yasmine El-Shamayleh, and Gregory D. Horwitz. "AAV-mediated delivery of optogenetic constructs to the macaque brain triggers humoral immune responses." Journal of Neurophysiology 117, no. 5 (May 1, 2017): 2004–13. http://dx.doi.org/10.1152/jn.00780.2016.
Full textDavis, Adam S., Thais Federici, William C. Ray, Nicholas M. Boulis, Deirdre O'Connor, K. Reed Clark, and Jeffrey S. Bartlett. "Rational Design and Engineering of a Modified Adeno-Associated Virus (AAV1)-Based Vector System for Enhanced Retrograde Gene Delivery." Neurosurgery 76, no. 2 (December 29, 2014): 216–25. http://dx.doi.org/10.1227/neu.0000000000000589.
Full textLunev, Evgenii, Anna Karan, Tatiana Egorova, and Maryana Bardina. "Adeno-Associated Viruses for Modeling Neurological Diseases in Animals: Achievements and Prospects." Biomedicines 10, no. 5 (May 15, 2022): 1140. http://dx.doi.org/10.3390/biomedicines10051140.
Full textLing, Chen, Yuan Wang, Yuan Lu, Lina Wang, Giridhara R. Jayandharan, George V. Aslanidi, Baozheng Li, et al. "Enhanced Transgene Expression from Recombinant Single-Stranded D-Sequence-Substituted Adeno-Associated Virus Vectors in Human Cell LinesIn Vitroand in Murine HepatocytesIn Vivo." Journal of Virology 89, no. 2 (October 29, 2014): 952–61. http://dx.doi.org/10.1128/jvi.02581-14.
Full textHampson, David, Alexander Hooper, and Yosuke Niibori. "The Application of Adeno-Associated Viral Vector Gene Therapy to the Treatment of Fragile X Syndrome." Brain Sciences 9, no. 2 (February 2, 2019): 32. http://dx.doi.org/10.3390/brainsci9020032.
Full textGorovits, Boris, Jean-Claude Marshall, Justin Smith, Laurence O. Whiteley, and Hendrik Neubert. "Bioanalysis of adeno-associated virus gene therapy therapeutics: regulatory expectations." Bioanalysis 11, no. 21 (November 2019): 2011–24. http://dx.doi.org/10.4155/bio-2019-0135.
Full textAssaf, Basel T., and Laurence O. Whiteley. "Considerations for Preclinical Safety Assessment of Adeno-Associated Virus Gene Therapy Products." Toxicologic Pathology 46, no. 8 (October 7, 2018): 1020–27. http://dx.doi.org/10.1177/0192623318803867.
Full textArruda, Valder R., Hansell H. Stedman, Virginia Haurigot, George Buchlis, Stefano Baila, Patricia Favaro, Yifeng Chen, et al. "Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B." Blood 115, no. 23 (June 10, 2010): 4678–88. http://dx.doi.org/10.1182/blood-2009-12-261156.
Full textAkcan, Tugce, Sam Spyra, Hans W. Sollinger, and Tausif Alam. "LBSUN178 Teniposide Improves Adeno-associated Virus-mediated Insulin Gene Therapy In Diabetic Mice." Journal of the Endocrine Society 6, Supplement_1 (November 1, 2022): A282—A283. http://dx.doi.org/10.1210/jendso/bvac150.583.
Full textSchnepp, Bruce C., Ryan L. Jensen, Chun-Liang Chen, Philip R. Johnson, and K. Reed Clark. "Characterization of Adeno-Associated Virus Genomes Isolated from Human Tissues." Journal of Virology 79, no. 23 (December 15, 2005): 14793–803. http://dx.doi.org/10.1128/jvi.79.23.14793-14803.2005.
Full textMadrigal, Justin L., Shahin Shams, Roberta S. Stilhano, and Eduardo A. Silva. "Characterizing the encapsulation and release of lentivectors and adeno-associated vectors from degradable alginate hydrogels." Biomaterials Science 7, no. 2 (2019): 645–56. http://dx.doi.org/10.1039/c8bm01218k.
Full textChen, Songfeng, Ming Luo, Hongwei Kou, Guowei Shang, Yanhui Ji, and Hongjian Liu. "A Review of Gene Therapy Delivery Systems for Intervertebral Disc Degeneration." Current Pharmaceutical Biotechnology 21, no. 3 (March 17, 2020): 194–205. http://dx.doi.org/10.2174/1389201020666191024171618.
Full textPegoraro, Gianluca, Alessandro Marcello, Michael P. Myers, and Mauro Giacca. "Regulation of Adeno-Associated Virus DNA Replication by the Cellular TAF-I/Set Complex." Journal of Virology 80, no. 14 (July 15, 2006): 6855–64. http://dx.doi.org/10.1128/jvi.00383-06.
Full textGuilbaud, Mickaël, Gilliane Chadeuf, Fabio Avolio, Achille François, Philippe Moullier, Alessandra Recchia, and Anna Salvetti. "Relative Influence of the Adeno-Associated Virus (AAV) Type 2 p5 Element for Recombinant AAV Vector Site-Specific Integration." Journal of Virology 82, no. 5 (December 19, 2007): 2590–93. http://dx.doi.org/10.1128/jvi.01956-07.
Full textYan, Ziying, Roman Zak, G. W. Gant Luxton, Teresa C. Ritchie, Ursula Bantel-Schaal, and John F. Engelhardt. "Ubiquitination of both Adeno-Associated Virus Type 2 and 5 Capsid Proteins Affects the Transduction Efficiency of Recombinant Vectors." Journal of Virology 76, no. 5 (March 1, 2002): 2043–53. http://dx.doi.org/10.1128/jvi.76.5.2043-2053.2002.
Full textBharadwaj, Arpita S., Meagan Kelly, Dongsoo Kim, and Hengjun Chao. "Induction of immune tolerance to FIX by intramuscular AAV gene transfer is independent of the activation status of dendritic cells." Blood 115, no. 3 (January 21, 2010): 500–509. http://dx.doi.org/10.1182/blood-2009-08-239509.
Full textWendtner, Clemens-Martin, David M. Kofler, Hans D. Theiss, Christian Kurzeder, Raymund Buhmann, Carmen Schweighofer, Luca Perabo, et al. "Efficient gene transfer of CD40 ligand into primary B-CLL cells using recombinant adeno-associated virus (rAAV) vectors." Blood 100, no. 5 (September 1, 2002): 1655–61. http://dx.doi.org/10.1182/blood.v100.5.1655.h81702001655_1655_1661.
Full textNakai, Hiroyuki, Roland W. Herzog, J. Nathan Hagstrom, Johannes Walter, Szu-Hao Kung, Edmund Y. Yang, Shing Jen Tai, et al. "Adeno-Associated Viral Vector-Mediated Gene Transfer of Human Blood Coagulation Factor IX Into Mouse Liver." Blood 91, no. 12 (June 15, 1998): 4600–4607. http://dx.doi.org/10.1182/blood.v91.12.4600.412k22_4600_4607.
Full textNam, Hyun-Joo, Michael Douglas Lane, Eric Padron, Brittney Gurda, Robert McKenna, Erik Kohlbrenner, George Aslanidi, et al. "Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector." Journal of Virology 81, no. 22 (August 29, 2007): 12260–71. http://dx.doi.org/10.1128/jvi.01304-07.
Full textMurlidharan, Giridhar, Travis Corriher, H. Troy Ghashghaei, and Aravind Asokan. "Unique Glycan Signatures Regulate Adeno-Associated Virus Tropism in the Developing Brain." Journal of Virology 89, no. 7 (January 28, 2015): 3976–87. http://dx.doi.org/10.1128/jvi.02951-14.
Full textNakai, Hiroyuki, Roland W. Herzog, J. Nathan Hagstrom, Johannes Walter, Szu-Hao Kung, Edmund Y. Yang, Shing Jen Tai, et al. "Adeno-Associated Viral Vector-Mediated Gene Transfer of Human Blood Coagulation Factor IX Into Mouse Liver." Blood 91, no. 12 (June 15, 1998): 4600–4607. http://dx.doi.org/10.1182/blood.v91.12.4600.
Full textMartino, Ashley T., Masataka Suzuki, David M. Markusic, Irene Zolotukhin, Renee C. Ryals, Babak Moghimi, Hildegund C. J. Ertl, Daniel A. Muruve, Brendan Lee, and Roland W. Herzog. "The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver." Blood 117, no. 24 (June 16, 2011): 6459–68. http://dx.doi.org/10.1182/blood-2010-10-314518.
Full textDuan, Dongsheng, Prerna Sharma, Jusan Yang, Yongping Yue, Lorita Dudus, Yulong Zhang, Krishna J. Fisher, and John F. Engelhardt. "Circular Intermediates of Recombinant Adeno-Associated Virus Have Defined Structural Characteristics Responsible for Long-Term Episomal Persistence in Muscle Tissue." Journal of Virology 72, no. 11 (November 1, 1998): 8568–77. http://dx.doi.org/10.1128/jvi.72.11.8568-8577.1998.
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