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Author: Grafiati

Published: 23 September 2022

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1

Malak, S. "Leucémies liées à des traitements anticancéreux : spécificités, difficultés et perspectives." Psycho-Oncologie 11, no. 4 (December 2017): 203–9. http://dx.doi.org/10.3166/s11839-017-0632-z.

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Les leucémies liées à des traitements anticancéreux, radio- ou chimiothérapies sont des maladies rares, mais redoutables. De nombreux défis attendent chacun des intervenants à chaque étape de ces prises en charge. Notamment, les soignants pourront éprouver la culpabilité liée à la possible causalité avec les traitements antérieurs et les difficultés d'une information appropriée dans un contexte d'incertitude. Pour les personnes malades et les proches, la difficulté légitime face à une maladie inattendue vécue comme une double peine, l'inquiétude d'être porteur d'un terrain génétique à risque, les interrogations sur la causalité pouvant impacter avec la relation médecin–patient et, parfois paradoxalement, une plus grande adaptation que lors du premier cancer. Ces maladies nécessitent des traitements urgents et souvent intensifs, qui ne peuvent parfois être conduits de façon optimale, justement, du fait des thérapeutiques antérieurement reçues. Cependant, les évolutions actuelles tant sur le plan de la compréhension que des possibilités de se prémunir de ces maladies, et sur l'amélioration des conditions de traitements, ouvrent des perspectives jusqu'ici inespérées.

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Li, Hangyang, Yunshan Zhou, Huanjian Xiong, Bing Fu, and Zhiliang Huang. "Real-Time Control Strategy for CVT-Based Hybrid Electric Vehicles Considering Drivability Constraints." Applied Sciences 9, no. 10 (May 20, 2019): 2074. http://dx.doi.org/10.3390/app9102074.

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The energy management strategy has a great influence on the fuel economy of hybrid electric vehicles, and the equivalent consumption minimization strategy (ECMS) has proved to be a useful tool for the real-time optimal control of Hybrid Electric Vehicles (HEVs). However, the adaptation of the equivalent factor poses a major challenge in order to obtain optimal fuel consumption as well as robustness to varying driving cycles. In this paper, an adaptive-ECMS based on driving pattern recognition (DPR) is established for hybrid electric vehicles with continuously variable transmission. The learning vector quantization (LVQ) neural network model was adopted for the on-line DPR algorithm. The influence of the battery state of charge (SOC) on the optimal equivalent factor was studied under different driving patterns. On this basis, a method of adaptation of the equivalent factor was proposed by considering the type of driving pattern and the battery SOC. Besides that, in order to enhance drivability, penalty terms were introduced to constrain frequent engine on/off events and large variations of the continuously variable transmission (CVT) speed ratio. Simulation results showed that the proposed method efficiently improved the equivalent fuel consumption with charge-sustaining operations and also took into account driving comfort.

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Lin, Xinyou, Qigao Feng, Liping Mo, and Hailin Li. "Optimal adaptation equivalent factor of energy management strategy for plug-in CVT HEV." Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering 233, no. 4 (March 5, 2018): 877–89. http://dx.doi.org/10.1177/0954407018755612.

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This study presents an adaptive energy management control strategy developed by optimally adjusting the equivalent factor (EF) in real-time based on driving pattern recognition (DPR), to guarantee the plug-in hybrid electric vehicle (PHEV) can adapt to various driving cycles and different expected trip distances and to further improve the fuel economy performance. First, the optimization model for the EF with the battery state of charge (SOC) and trip distance were developed based on the equivalent consumption minimization strategy (ECMS). Furthermore, a methodology of extracting the globally optimal EF model from genetic algorithm (GA) solution is proposed for the design of the EF adaptation strategy. The EF as the function of trip distances and SOC in various driving cycles is expressed in the form of map that can be applied directly in the corresponding driving cycle. Finally, the algorithm of DPR based on learning vector quantization (LVQ) is established to identify the driving mode and update the optimal EF. Simulation and hardware-in-loop experiments are conducted on synthesis driving cycles to validate the proposed strategy. The results indicate that the optimal adaption EF control strategy will be able to adapt to different expected trip distances and improve the fuel economy performance by up to 13.8% compared to the ECMS with constant EF.

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Pérez, Wilson, Punit Tulpule, Shawn Midlam-Mohler, and Giorgio Rizzoni. "Data-Driven Adaptive Equivalent Consumption Minimization Strategy for Hybrid Electric and Connected Vehicles." Applied Sciences 12, no. 5 (March 5, 2022): 2705. http://dx.doi.org/10.3390/app12052705.

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Advanced energy management strategies (EMS) are used to control the power flow through a vehicle’s powertrain. However, the cost of high-power computational hardware and lack of a priori knowledge of future road conditions poses difficult challenges for engineers attempting to implement globally optimal frameworks. One solution is to use advanced driver assistance systems (ADAS) and connectivity to obtain a prediction of future road conditions. This paper presents a look-ahead predictive EMS which combines approximate dynamic programming (ADP) methods and an adaptive equivalent consumption minimization strategy (A-ECMS) to obtain a near-optimal solution for a future prediction horizon. ECMS is highly sensitive to the equivalence factor (EF), making it necessary to adapt during a trip to account for disturbances. A novel adaptation method is presented in this work which uses an artificial neural network to learn the nonlinear relationship between a speed and the state of charge (SOC) trajectory prediction obtained from ADP to estimate the corresponding EF. A traffic uncertainty analysis demonstrates an approximately 10% fuel economy (FE) improvement over traditional A-ECMS. Using a data-driven adaptation method for A-ECMS informed by a dynamic programming (DP) based prediction results in an EMS capable of online implementation.

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5

Barbasova, T. A. "A MULTILEVEL RESOURCE-SAVING BLAST FURNACE PROCESS CONTROL." Bulletin of the South Ural State University. Ser. Computer Technologies, Automatic Control & Radioelectronics 21, no. 1 (February 2021): 136–46. http://dx.doi.org/10.14529/ctcr210112.

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A multilevel resource-saving blast furnace process control is considered. The resource-saving control is provided for operating, adaptation, technical and economic control in the automated systems of blast-furnace processes. It is proposed to form optimal operation modes of blast furnace heating, metal charge structures, natural gas and oxygen consumption. Decisions are made using Kohonen neural networks taking into account current and planned parameters of coke quality, iron ore, raw materials and blast. At the level of operating control, the work suggests a model predictive control to improve the resource conservation indicators. The method is based on decomposition of the general problem of the process dynamics identification on particular problems: dynamic synchronization and identification of process transfer functions. At the level of adaptive control, optimal operating modes of blast furnaces are expedient to be developed with respect to blast furnace heating, structure of metal charge, natural gas and oxygen rate considering the current and planned parameters of coke, blasting. The blast furnace operating modes are suggested to be determined based on Kohonen neural networks. In evaluating the efficiency of introducing the model predictive control, the existing actual statistics of scatter of BF mode parameters should be based upon. The fact is that the introduction of model predictive control assumes no radical change of the BF melt technology. Like in all the control systems, the BF process is considered as the set control object with all its characteristics. Changing process settings, raw material content does not introduce any cardinal variation in the scatter of process characteristics. However, in this case a transient process occurs which is necessary for the control system to identify the changing conditions. The transient process is inherent to all the control systems and the blast furnace process is not an exclusion. As a result of transient process, the control system is set to the optimal mode.

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6

Roudaut, R. "L’insuffisance mitrale : pour une prise en charge optimale." Archives des Maladies du Coeur et des Vaisseaux - Pratique 2009, no. 183 (December 2009): 8. http://dx.doi.org/10.1016/s1261-694x(09)73512-6.

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7

Lefort, A. "Endocardites fongiques : quelle prise en charge thérapeutique optimale ?" La Revue de Médecine Interne 26, no. 6 (June 2005): 441–43. http://dx.doi.org/10.1016/j.revmed.2005.03.003.

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8

Dumas, Patrice, and Minh Ha-Duong. "Optimal growth with adaptation to climate change." Climatic Change 117, no. 4 (October 26, 2012): 691–710. http://dx.doi.org/10.1007/s10584-012-0601-7.

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9

Borysenko, Oksana, Sergii Logvinkov, Halyna Shabanova, Igor Ostapenko, and Olena Gaponova. "PERICLASE-SPINEL REFRACTORY MODIFIED ТІО2." Bulletin of the National Technical University "KhPI". Series: Chemistry, Chemical Technology and Ecology, no. 2(6) (December 23, 2021): 9–14. http://dx.doi.org/10.20998/2079-0821.2021.02.02.

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Over the past decades, the development and improvement of refractory materials for lining high-temperature zones of rotary kilns continues. The main requirements for refractory products for lining rotary kilns for cement clinker roasting are: high density and ultimate compressive strength, low porosity and gas permeability, increased abrasion resistance, low thermal conductivity, high corrosion resistance and the ability to form a protective layer.Today, the main goal of modern researchers is to create a heat-resistant refractory with a flexible structure that ensures its integrity at high temperatures and mechanical loads, which have the ability to form a protective coating layer. In this work, a technological approach has been tested for introducing a vibro-milled modifier (briquette based on a high-alumina component and a titanium-containing additive) into the composition of the raw charge for periclase-spinel refractory in the form of a pre-synthesized product containing crystalline phases of the Al2O3 – TiO2 – FeO system. The basis for the production of periclase-spinel refractories modified with TiO2 is the four-component system MgO – Al2O3 – FeO – TiO2, on the basis of thermodynamic calculations of which the content of individual components of the charge was selected and the operational characteristics were predicted. The interrelation of physical and mechanical properties with the content of individual components in the initial charge warehouses is shown, and the directions of solid-phase processes with their participation are noted. The features of the microstructure of the sample material are noted in relation to the formation of an optimal set of properties. It is shown that the nature of the organization of micropores is favorable for increasing the thermal stability of the material, which complements the phase adaptation mechanism also with the structural effect of damping mechanical stresses during thermal cycling.

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Hodgson, Nancy, and Laura Gitlin. "Tracking Adaptation and Fidelity When Embedding COPE, Evidence-Based Dementia Care, in PACE Sites." Innovation in Aging 5, Supplement_1 (December 1, 2021): 174. http://dx.doi.org/10.1093/geroni/igab046.664.

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Abstract One essential question in moving dementia care interventions to practice is, “What is the optimal balance between fidelity to, and adaptation of, a proven program in “real world” settings?" We present a protocol for measuring the adaptation/fidelity and implementation of an evidence-based dementia care program (Care of Persons in their Environment, COPE) in PACE settings. During pre-implementation, science-based elements of COPE were documented including the theory of change, logic model and core components. Possible adaptations to COPE in its delivery were identified and included program structure (sequence of sessions), content (assessments), and delivery methods (online). During implementation, documentation of implementation strategies is captured using an evidence-informed checklist derived from the Expert Recommendations for Implementing Change (ERIC) workgroup. Ongoing documentation of fidelity/adaptation aspects of program implementation is conducted using the FRAME framework. Understanding methods and measures deployed in adaptation and implementation of evidence-based dementia programs can help guide future translation efforts.

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11

Mounier-Vehier, Claire. "Prise en charge non optimale de l’hypertension artérielle : qui résiste ?" JMV-Journal de Médecine Vasculaire 45 (March 2020): S14. http://dx.doi.org/10.1016/j.jdmv.2020.01.032.

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Mounier-Véhier, Claire. "Prise en charge non optimale de l’hypertension artérielle : qui résiste ?" JMV-Journal de Médecine Vasculaire 45 (November 2020): S82. http://dx.doi.org/10.1016/j.jdmv.2020.10.023.

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Mounier-Véhier, Claire. "Prise en charge non optimale de l’hypertension artérielle : qui résiste ?" JMV-Journal de Médecine Vasculaire 46, no. 5 (October 2021): S16. http://dx.doi.org/10.1016/j.jdmv.2021.08.006.

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14

WANG, WEIWEI, and BRUCE A. McCARL. "TEMPORAL INVESTMENT IN CLIMATE CHANGE ADAPTATION AND MITIGATION." Climate Change Economics 04, no. 02 (May 2013): 1350009. http://dx.doi.org/10.1142/s2010007813500097.

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Increasingly there appears to be recognition of the need to simultaneously implement adaptation and mitigation. However, the optimal combination of adaptation and mitigation is an open question. The literature on this is rather small, and is inconsistent in conclusions. Here we explore the temporal optimal investment mix between adaptation and mitigation and their relative contributions to damage reduction. We do this using a conceptual framework that integrates mitigation and adaptation considering one time flow and persistent stock adaptation. We also consider unadaptable damages and investment competition. Results suggest that stock and flow adaptation are dominant damage reduction means in the first 120 years while mitigation dominates from thereon. We also find that the adaptation/mitigation mix changes markedly toward mitigation when climate change damages per unit atmospheric CO 2 concentration rises.

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Georgiou, Pantazis E., and Dimitrios K. Karpouzos. "Optimal irrigation water management for adaptation to climate change." International Journal of Sustainable Agricultural Management and Informatics 3, no. 4 (2017): 271. http://dx.doi.org/10.1504/ijsami.2017.090608.

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Georgiou, Pantazis E., and Dimitrios K. Karpouzos. "Optimal irrigation water management for adaptation to climate change." International Journal of Sustainable Agricultural Management and Informatics 3, no. 4 (2017): 271. http://dx.doi.org/10.1504/ijsami.2017.10011777.

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17

BOSELLO, FRANCESCO, CARLO CARRARO, and ENRICA DE CIAN. "CLIMATE POLICY AND THE OPTIMAL BALANCE BETWEEN MITIGATION, ADAPTATION AND UNAVOIDED DAMAGE." Climate Change Economics 01, no. 02 (August 2010): 71–92. http://dx.doi.org/10.1142/s201000781000008x.

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It has become commonly accepted that a successful climate strategy should compound mitigation and adaptation. The accurate combination between adaptation and mitigation that can best address climate change is still an open question. This paper proposes a framework that integrates mitigation, adaptation, and climate change residual damages into an optimisation model. This set-up is used to provide some insights on the welfare maximising resource allocation between mitigation and adaptation, on their optimal timing, and on their marginal contribution to reducing vulnerability to climate change. The optimal mix between three different adaptation modes (reactive adaptation, anticipatory adaptation, and investment in innovation for adaptation purposes) within the adaptation bundle is also identified. Results suggest that the joint implementation of mitigation and adaptation is welfare improving. Mitigation should start immediately, whereas adaptation somewhat later. It is also shown that in a world where the probability of climate-related catastrophic events is small and where decision makers have a high discount rate, adaptation is unambiguously the preferred option. Adaptation needs, both in developed and developing countries, will be massive, especially during the second half of the century. Most of the adaptation burden will be on developing countries. International cooperation is thus required to equally distribute the costs of adaptation.

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Thomas, T., J. M. Feron, P. D. Delmas, J. Kaufman, L. Tosi, S. Cummings, J. Lane, O. Johnell, and M. L. Bouxsein. "Prise en charge optimale des patients présentant une fracture de fragilité." Revue de Chirurgie Orthopédique et Réparatrice de l'Appareil Moteur 92, no. 2 (April 2006): 165–74. http://dx.doi.org/10.1016/s0035-1040(06)75702-6.

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19

Duteille, Franck. "Une collaboration ville-hôpital indispensable pour une prise en charge optimale." Revue Francophone de Cicatrisation 3, no. 2 (April 2019): 9. http://dx.doi.org/10.1016/j.refrac.2019.04.003.

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20

Bassand, Jean-Pierre, M. Bertrand, K. Fox, Nicolas Danchin, and Marie Solignac. "Vers une prise en charge optimale du coronarien stable en 2004." La Presse Médicale 33, no. 16 (September 2004): 1074–76. http://dx.doi.org/10.1016/s0755-4982(04)98850-1.

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21

Arvieux, C. "Vers une prise en charge optimale du traumatisé grave en France." Journal de Chirurgie Viscérale 153, no. 4 (August 2016): 1–2. http://dx.doi.org/10.1016/j.jchirv.2016.04.006.

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22

Millner, Antony, and Simon Dietz. "Adaptation to climate change and economic growth in developing countries." Environment and Development Economics 20, no. 3 (November 25, 2014): 380–406. http://dx.doi.org/10.1017/s1355770x14000692.

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AbstractDeveloping countries are vulnerable to the adverse effects of climate change, yet there is disagreement about what they should do to protect themselves from anticipated damages. In particular, it is unclear what the optimal balance is between investments in traditional productive capital (which increases output but is vulnerable to climate change), and investments in adaptive capital (which is unproductive in the absence of climate change but ‘climate-proofs’ vulnerable capital). We develop a model of investment in adaptive and productive capital stocks, and show that while it is unlikely that the optimal strategy involves no adaptation, the scale and composition of optimal investments depends on empirical context. Application of our model to sub-Saharan Africa suggests, however, that in most contingencies it will be optimal to grow the adaptive sector more rapidly than the vulnerable sector over the coming decades, although it never exceeds 1 per cent of the economy. Our sensitivity analysis goes well beyond the existing literature in evaluating the robustness of this finding.

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Mahé, Isabelle, Ygal Benhamou, Hélène Helfer, and Jean Chidiac. "Cancer et récidive thromboembolique veineuse : les clés d’une prise en charge optimale." Bulletin du Cancer 105, no. 5 (May 2018): 508–16. http://dx.doi.org/10.1016/j.bulcan.2017.12.006.

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Verhavert, G., T. Verdonck, S. Pazmino, V. Stouten, D. Bertrand, M. Doumen, R. Westhovens, P. Verschueren, and D. De Cock. "POS1434 WHICH PROGNOSTIC FACTORS MIGHT PREDICT THE NEED FOR TREATMENT ADAPTATION IN EARLY RHEUMATOID ARTHRITIS? A COMPARISON OF MACHINE LEARNING, SURVIVAL ANALYSIS AND REGRESSION METHODS." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 1001.2–1002. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2717.

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Background:Current EULAR guidelines recommend treating RA early, intensively and to-target. A data-driven tool for planning the optimal moment for subsequent visits might adapt visit schedules more to the patient’s needs, without losing treatment quality.Objectives:To determine the optimal statistical model and clinical factors to predict the time to a treatment adaptation in early RA patients.Methods:This study included 379 patients from the treat-to-target Care in Rheumatoid Arthritis (CareRA) trial. The CareRA protocol included 2 predefined treatment adaptation steps for patients not reaching low disease activity (DAS28CRP<3.2). The 1st adaptation was an MTX dose increase and the second one was adding/increasing the dose of a 2nd csDMARD. Three predictive models (Cox Proportional Hazards, Linear Multi-Task Regression and Random Survival Forest) were trained and validated to predicting time until these 2 adaptations. Factor selection for these models was performed by applying Cox Proportional Hazards with LASSO penalty to each set of demographic and clinical variables recorded at baseline, w4 and w8. Models used these factors at these 3 time points to predict future treatment adaptations. Model performance was estimated by the Uno Concordance Index with five-fold cross-validation. Missing data were imputed by interpolation or mean score.Results:Factors selected to predict the first per protocol change included TJC, SJC, HAQ, CRP, pain and morning stiffness>15min. Factors selected to predict the second per protocol change included TJC, SJC, PGA, PhGA. Uno Concordance indices showed similar scores per different statistical model but higher scores at w4 and w8 compared to baseline indicating a better predictive performance (Table 1. next page).Table 1.Uno Concordance Scores. Format ‘mean (min-max)’.BaselineWeek 4Week 8Cox Proportional HazardsChange 10.63 (0.59-0.69)0.72 (0.68-0.80)0.75 (0.69-0.82)Change 20.58 (0.50-0.66)0.75 (0.65-0.87)0.78 (0.65-0.93)Linear Multi-Task RegressionChange 10.65 (0.62-0.68)0.72 (0.68-0.78)0.75 (0.69-0.79)Change 20.58 (0.51-0.68)0.72 (0.67-0.82)0.77 (0.68-0.89)Random Survival ForestChange 10.64 (0.58-0.67)0.71 (0.66-0.78)0.76 (0.68-0.80)Change 20.56 (0.50-0.68)0.72 (0.60-0.82)0.77 (0.64-0.92)Conclusion:Our data-driven approach identified predictive clinical factors with a high face validity including joint counts, functionality scores and global health indicators. The different model approaches did not seem to increase the predictive capacity performance. However, our results underline that not so much the baseline disease status but rather the early response to initial treatment reflected in the selected predictive factors can be used for prediction of the need for further treatment adaptation. These models will have to be enriched with patient reported outcomes to further improve predictive performance.Disclosure of Interests:None declared

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Carrère, S., R. Tetreau, C. Honoré, D. Tzanis, J. B. Delhorme, M. Fau, G. Decanter, et al. "Quelle prise en charge optimale pour un sarcome du cordon spermatique en 2018 ?" Progrès en Urologie 29, no. 1 (January 2019): 12–17. http://dx.doi.org/10.1016/j.purol.2018.09.010.

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Weitensfelder, Lisbeth, and Hanns Moshammer. "Evidence of Adaptation to Increasing Temperatures." International Journal of Environmental Research and Public Health 17, no. 1 (December 21, 2019): 97. http://dx.doi.org/10.3390/ijerph17010097.

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In times of rising temperatures, the question arises on how the human body adapts. When assumed that changing climate leads to adaptation, time series analysis should reveal a shift in optimal temperatures. The city of Vienna is especially affected by climate change due to its location in the Alpine Range in Middle Europe. Based on mortality data, we calculated shifts in optimal temperature for a time period of 49 years in Vienna with Poisson regression models. Results show a shift in optimal temperature, with optimal temperature increasing more than average temperature. Hence, results clearly show an adaptation process, with more adaptation to warmer than colder temperatures. Nevertheless, some age groups remain more vulnerable than others and less able to adapt. Further research focusing on vulnerable groups should be encouraged.

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Abrams, Alicia B., James M. Hillis, and David H. Brainard. "The Relation Between Color Discrimination and Color Constancy: When Is Optimal Adaptation Task Dependent?" Neural Computation 19, no. 10 (October 2007): 2610–37. http://dx.doi.org/10.1162/neco.2007.19.10.2610.

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Color vision supports two distinct visual functions: discrimination and constancy. Discrimination requires that the visual response to distinct objects within a scene be different. Constancy requires that the visual response to any object be the same across scenes. Across changes in scene, adaptation can improve discrimination by optimizing the use of the available response range. Similarly, adaptation can improve constancy by stabilizing the visual response to any fixed object across changes in illumination. Can common mechanisms of adaptation achieve these two goals simultaneously? We develop a theoretical framework for answering this question and present several example calculations. In the examples studied, the answer is largely yes when the change of scene consists of a change in illumination and considerably less so when the change of scene consists of a change in the statistical ensemble of surface reflectances in the environment.

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Pavlov, M. Y., and M. Ehrenberg. "Optimal control of gene expression for fast proteome adaptation to environmental change." Proceedings of the National Academy of Sciences 110, no. 51 (December 2, 2013): 20527–32. http://dx.doi.org/10.1073/pnas.1309356110.

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Ismail, Tarmizi, Sobri Harun, Zaitul Marlizawati Zainudin, Shamsuddin Shahid, Abu Bakar Fadzil, and Usman Ullah Sheikh. "Development of an optimal reservoir pumping operation for adaptation to climate change." KSCE Journal of Civil Engineering 21, no. 1 (April 11, 2016): 467–76. http://dx.doi.org/10.1007/s12205-016-0641-z.

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HRITONENKO, NATALI, and YURI YATSENKO. "MODELING OF ENVIRONMENTAL ADAPTATION: AMENITY VERSUS PRODUCTIVITY AND MODERNIZATION." Climate Change Economics 04, no. 02 (May 2013): 1350006. http://dx.doi.org/10.1142/s2010007813500061.

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We develop an aggregated model to study rational environmental adaptation policies that compensate negative consequences of climate change. The model distinguishes three categories of adaptation measures that (a) compensate the decrease of environmental amenity value, (b) compensate the decrease of total productivity, (c) develop and introduce new hazard-protected capital and technology. We analyze the optimal balance among consumption, capital investment, and different categories of adaptation investments under exogenous climate change. It appears that the climate change damage and subsequent adaptation do not lead to a higher level of capital modernization in the long run as compared to the benchmark case with no climate change. A synergism between productivity-related and amenity-related adaptation activities arises because the productivity-related adaptation positively impacts the economy and creates better possibilities for the amenity adaptation.

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Bosello, Francesco, Carlo Carraro, and Enrica De Cian. "Adaptation can help mitigation: an integrated approach to post-2012 climate policy." Environment and Development Economics 18, no. 3 (April 29, 2013): 270–90. http://dx.doi.org/10.1017/s1355770x13000132.

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AbstractThis paper analyzes the optimal mix of adaptation and mitigation expenditures in a cost-effective setting, in which countries cooperate to achieve a long-term stabilization target (550 CO2-eq). It uses an Integrated Assessment Model (AD-WITCH) that describes the relationships between different adaptation modes (reactive and anticipatory), mitigation and capacity building to analyze the optimal portfolio of adaptation measures. Results show that the optimal intertemporal distribution of climate policy measures is characterized by early investments in mitigation followed by large adaptation expenditures a few decades later. Hence, the possibility of adapting does not justify postponing mitigation. Moreover, a climate change policy combining mitigation and adaptation is less costly than mitigation alone. In this sense mitigation and adaptation are shown to be strategic complements rather than mutually exclusive.

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Vong, L. V., H. Dekadjevi, S. Jochmans, D. Sapir, G. Lecardinal, B. Pamar, N. Rollin, and K. Tazarourte. "Prise en charge des pneumothorax compressifs en médecine d'urgence: la formation est-elle optimale?" Journal Européen des Urgences 20, no. 1 (May 2007): 8. http://dx.doi.org/10.1016/j.jeur.2007.03.089.

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Fayette, J., J. Y. Blay, and I. Ray-Coquard. "Les sarcomes des tissus mous : bonnes pratiques médicales pour une prise en charge optimale." Cancer/Radiothérapie 10, no. 1-2 (February 2006): 3–6. http://dx.doi.org/10.1016/j.canrad.2005.09.026.

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34

Salomon, G., and F. Giordano-Labadie. "Allergie aux acrylates et électrodes : un frein à une prise en charge médicale optimale ?" Annales de Dermatologie et de Vénéréologie 145, no. 12 (December 2018): S149. http://dx.doi.org/10.1016/j.annder.2018.09.188.

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Lewis, Clint T., and Ming-Chien Su. "Climate Change Adaptation and Sectoral Policy Coherence in the Caribbean." Sustainability 13, no. 15 (July 30, 2021): 8518. http://dx.doi.org/10.3390/su13158518.

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Climate change is an existential threat to small island developing states. Policy coherence aims to create synergies and avoid conflicts between policies. Mainstreaming adaptation across multiple sectors and achieving greater coherence amongst policies is needed. The paper applies qualitative document analysis, content analysis, and expert interviews to examine the degree of coherence between climate-sensitive sector policies in framing climate change adaptation and the adaptation goals outlined in the national development plan and national climate change policies in St. Vincent and the Grenadines (SVG), Grenada, and Saint Lucia. The results indicate that adaptation is not fully integrated into the water, agriculture, coastal zone, and forestry policies. For example, while adaptation was explicitly addressed in Saint Lucia’s water policy, it was not explicitly addressed in SVG’s and Grenada’s water policy. The results show that Saint Lucia has the highest coherence score (93.52) while St. Vincent and the Grenadines has the lowest (91.12). The optimal coherence score that can be possibly obtained is 147, which indicates partial coherence in adaptation mainstreaming in sectoral policies. Expert interviews highlighted problems such as institutional arrangements, a silo approach, funding mechanisms, and policy implementation. Using the knowledge provided by the experts, a seven-step process is proposed to practically achieve policy coherence and operationalize the policies.

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Ondongh-Essalt, Etsianat, and Catherine Flot. "Ethnopsychiatrie et travail social : éléments cliniques et socio-anthropologiques pour un interpartenariat efficace autour des familles." III. À la naissance de l’informel : le travail de mise en forme des praticiens, no. 32 (October 2, 2002): 163–78. http://dx.doi.org/10.7202/017779ar.

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RÉSUMÉ Les auteurs, un ethnopsychanalyste et une puéricultrice, proposent, à travers l'étude d'une observation clinique détaillée, l'analyse socio-anthropologique puis théorico-clinique de la prise en charge globale d'une famille africaine imbriquée dans de multiples conflits. Ils expliquent les conditions nécessaires à la création d'un groupe d'ethnopsychiatrie ad hoc ainsi que les moyens mis en œuvre pour obtenir l'efficacité optimale dans le travail d'une telle équipe. En conclusion, ils ébauchent une discussion théorique autour du concept opérationnel d'ethnopsychiatrie communautaire.

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Doughan, M., J. P. Hayet, J. David, and S. Lefeuvre. "Adaptation automatique de charge à 13,56 MHz." Revue de Physique Appliquée 23, no. 7 (1988): 1243–48. http://dx.doi.org/10.1051/rphysap:019880023070124300.

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Atolia, Manoj, Prakash Loungani, Helmut Maurer, and Willi Semmler. "Optimal Control of a Global Model of Climate Change with Adaptation and Mitigation." IMF Working Papers 18, no. 270 (2018): 1. http://dx.doi.org/10.5089/9781484387795.001.

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Felgenhauer, Tyler, and Kelly C. De Bruin. "The optimal paths of climate change mitigation and adaptation under certainty and uncertainty." International Journal of Global Warming 1, no. 1/2/3 (2009): 66. http://dx.doi.org/10.1504/ijgw.2009.027082.

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Spyridi, Dimitra, Christos Vlachokostas, Alexandra V. Michailidou, Constantinos Sioutas, and Nicolas Moussiopoulos. "Strategic planning for climate change mitigation and adaptation: the case of Greece." International Journal of Climate Change Strategies and Management 7, no. 3 (August 17, 2015): 272–89. http://dx.doi.org/10.1108/ijccsm-02-2014-0027.

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Purpose – The purpose of this study is to put forward a methodological framework to provide a comparative assessment of available mitigation and adaptation strategies against climate change. Mitigation options aim at minimizing CO2 and other greenhouse gas emissions, in an effort to reduce the rate of increase in global temperature. On the other hand, adaptation options relate to the ability of the natural or human systems to handle the impact of the climate change and to adjust to its effects, seeking to eliminate the adverse consequences and take advantage of any beneficial outcomes. Design/methodology/approach – The methodology focuses on specific parameters, leading to the most efficient package of alternatives for the area of Greece. The selection of the “optimal” ranking of alternatives in a defined strategy is a sophisticated procedure, and a multi-criteria decision-making process was established. A questionnaire was designed and used as input to the overall framework, based on specific decision criteria. Climate change experts gave their feedback via a face-to-face interview. ELECTRE III multi-criteria decision analysis was adopted for the comparative evaluation, as it fits best to complex environmental problems. An “optimal” sequence of mitigation and adaptation strategies was provided for Greece. Findings – The use of renewable energy sources, increase of energy efficiency and improved forest management – tree planting and rational water management – are among the most promising options to strategically plan climate change mitigation and adaptation for Greece. Originality/value – The presented study provides an insight into alternative mitigation and adaptation strategies against climate change. The use of the multi-criteria analysis is an innovative approach to outline the optimal bundle of strategies. The methodology focuses on specific parameters, leading to the most efficient package of measures for the area of Greece. Such an approach is implemented for the first time in Greece, at least up to the authors’ knowledge, and provides a basis for strategic governance and policy modeling for the area under consideration.

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Gohari, Alireza, Ali Bozorgi, Kaveh Madani, Jeffrey Elledge, and Ronny Berndtsson. "Adaptation of surface water supply to climate change in central Iran." Journal of Water and Climate Change 5, no. 3 (March 6, 2014): 391–407. http://dx.doi.org/10.2166/wcc.2014.189.

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Optimal reservoir operation changes and adaptation strategies for the Zayandeh-Rud River Basin's surface water supply system are examined for a changing climate during the 2015–2044 period. On average, the monthly temperature in the basin is expected to increase by 0.46–0.76 °C and annual precipitation is expected to decrease by 14–38% with climate change, resulting in a reduction of the Zayandeh-Rud's peak stream flow and the amplitude of its seasonal range. Snowfall decrease in winter months will generally lead to an 8–43% reduction in annual stream flow under climate change. A reservoir operation model is developed and optimal reservoir operation strategies are identified for adaptation of the basin's surface water supply to climate change in the face of the increasing water demand. Results indicate that the reservoir drawdown season starts 2 months earlier under climate change. Smaller storage levels and greater water releases must occur to meet the increasing water demand. The optimized water release can provide sufficient water for non-agricultural water demand, but agriculture will experience more severe water shortage under a changing climate. Having the highest vulnerability, the agricultural sector should be the main focus of regional management plans to address the current water challenge and more severe water shortages under climate change.

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Sauvanet, J. P. "Choisir de maîtriser son diabète : la clé pour une prise en charge optimale des patients." Médecine des Maladies Métaboliques 1, no. 4 (November 2007): 107–8. http://dx.doi.org/10.1016/s1957-2557(07)74164-0.

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Métahri, M., A. Snouber, S. Kebbati, K. Machou, and A. Dida. "Intérêt du phénotypage pour une prise en charge optimale des asthmes sévères suivis en pneumologie." Revue des Maladies Respiratoires Actualités 12, no. 1 (January 2020): 84–85. http://dx.doi.org/10.1016/j.rmra.2019.11.165.

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Kayem, G., and L. Sentilhes. "Quelle validation des compétences chirurgicales en oncologie pour une prise en charge optimale des patientes ?" Gynécologie Obstétrique Fertilité & Sénologie 50, no. 1 (January 2022): 1. http://dx.doi.org/10.1016/j.gofs.2021.11.002.

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Hu, Xian-Ge, Jian-Feng Mao, Yousry A. El-Kassaby, Kai-Hua Jia, Si-Qian Jiao, Shan-Shan Zhou, Yue Li, Nicholas C. Coops, and Tongli Wang. "Local Adaptation and Response of Platycladus orientalis (L.) Franco Populations to Climate Change." Forests 10, no. 8 (July 25, 2019): 622. http://dx.doi.org/10.3390/f10080622.

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Knowledge about the local adaptation and response of forest tree populations to the climate is important for assessing the impact of climate change and developing adaptive genetic resource management strategies. However, such information is not available for most plant species. Here, based on 69 provenances tested at 19 common garden experimental sites, we developed a universal response function (URF) for tree height at seven years of age for the important and wide-spread native Chinese tree species Platycladus orientalis (L.) Franco. URF was recently used to predict the potential growth response of a population originating from any climate and growing in any climate conditions. The developed model integrated both genetic and environmental effects, and explained 55% of the total variation in tree height observed among provenances and test sites in China. We found that local provenances performed better than non-local counterparts in habitats located in central, eastern, and southwestern China, showing the evidence of local adaptation as compared to other regions. In contrast, non-local provenances outperformed local ones in peripheral areas in northern and northwestern China, suggesting an adaptational lag in these areas. Future projections suggest that the suitable habitat areas of P. orientalis would expand by 15%–39% and shift northward by 0.8–3 degrees in latitude; however, the projected tree height of this species would decline by 4%–8% if local provenances were used. If optimal provenances were used, tree height growth could be improved by 13%–15%, along with 59%–71% suitable habitat expansion. Thus, assisted migration with properly selected seed sources would be effective in avoiding maladaptation in new plantations under a changing climate for P. orientalis.

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Thomas, T., N. C. Ghosh, and K. P. Sudheer. "Optimal reservoir operation – A climate change adaptation strategy for Narmada basin in central India." Journal of Hydrology 598 (July 2021): 126238. http://dx.doi.org/10.1016/j.jhydrol.2021.126238.

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Haer, Toon, W. J. Wouter Botzen, Vincent van Roomen, Harry Connor, Jorge Zavala-Hidalgo, Dirk M. Eilander, and Philip J. Ward. "Coastal and river flood risk analyses for guiding economically optimal flood adaptation policies: a country-scale study for Mexico." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 376, no. 2121 (April 30, 2018): 20170329. http://dx.doi.org/10.1098/rsta.2017.0329.

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Many countries around the world face increasing impacts from flooding due to socio-economic development in flood-prone areas, which may be enhanced in intensity and frequency as a result of climate change. With increasing flood risk, it is becoming more important to be able to assess the costs and benefits of adaptation strategies. To guide the design of such strategies, policy makers need tools to prioritize where adaptation is needed and how much adaptation funds are required. In this country-scale study, we show how flood risk analyses can be used in cost–benefit analyses to prioritize investments in flood adaptation strategies in Mexico under future climate scenarios. Moreover, given the often limited availability of detailed local data for such analyses, we show how state-of-the-art global data and flood risk assessment models can be applied for a detailed assessment of optimal flood-protection strategies. Our results show that especially states along the Gulf of Mexico have considerable economic benefits from investments in adaptation that limit risks from both river and coastal floods, and that increased flood-protection standards are economically beneficial for many Mexican states. We discuss the sensitivity of our results to modelling uncertainties, the transferability of our modelling approach and policy implications. This article is part of the theme issue ‘Advances in risk assessment for climate change adaptation policy’.

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Steurer-Stey. "Asthmaschulung und Selbstmanagement: wichtige Voraussetzung für eine optimale Asthmakontrolle und den langfristigen Erfolg im Alltag." Praxis 92, no. 16 (April 1, 2003): 745–50. http://dx.doi.org/10.1024/0369-8394.92.16.745.

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L'intuition, la disponibilité, l'expérience et la motivation sont des conditions importantes mais elles ne suffisent pas pour garantir une formation efficace et permettre un contrôle optimal de l'asthme. La formation doit être plus qu'une transmission de savoir. Il a été démontré que la seule transmission de savoir ne permet pas une modification du comportement et qu'aucun des buts thérapeutiques importants ne peut être ainsi obtenu. L'inclusion des aspects de la théorie de comportement dans le processus de formation tant des patients que des médecins et du personnel médical est cependant indispensable. Alors que la formation traditionnelle se base principalement sur la transmission de connaissances et la notion d'apprentissage de certaines capacités, la formation dans la prise en charge du traitement par le malade lui-même (autotraitement) apporte des ébauches de solutions orientées vers les problèmes et les buts. Elle exige une motivation propre et la participation active du patient comme partenaire ce qui est une condition importante pour un succès à long terme. La formation à l'autotraitement devrait et pourra, espérons-le, être à l'avenir une partie intégrale d'une prise en charge optimale de haute qualité pour les patients avec une maladie chronique telle que l'asthme.

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FAURE, M., V. PAULMIER, A. DE BOYER DES ROCHES, A. BOISSY, E. M. C. TERLOUW, R. GUATTEO, J. COGNIÉ, C. COURTEIX, and D. DURAND. "Douleurs animales. 2. Evaluation et traitement de la douleur chez les ruminants." INRA Productions Animales 28, no. 3 (January 13, 2020): 231–42. http://dx.doi.org/10.20870/productions-animales.2015.28.3.3028.

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Les ruminants sont des animaux sensibles, doués de capacités émotionnelles et cognitives, pouvant être soumis à différents types de douleur (excès de nociception ou neuropathique) et ceci dans différents contextes (élevage ou expérimentation). L’évaluation de ces douleurs est souvent délicate car, dans la plupart des cas, il n’existe pas d'outil unique et spécifique mais plutôt un ensemble d'indicateurs dont les valeurs informatives sont complémentaires. Une évaluation adéquate de la douleur est essentielle afin d'optimiser sa prise en charge en utilisant au mieux l'arsenal thérapeutique actuellement à la disposition des prescripteurs. A travers cette synthèse, nous montrerons en quoi i) l’évaluation du type et du niveau de douleur est indispensable à une prise en charge optimale de la douleur, ii) une évaluation reposant sur une approche multiparamétrique est l'approche la plus adaptée à cet objectif.

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Alaphilippe, D. "Psychologie du vieillissement : prise en charge et adaptation." European Review of Applied Psychology 57, no. 3 (September 2007): 133–36. http://dx.doi.org/10.1016/j.erap.2007.02.001.

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