Journal articles on the topic 'Acute myeloid leukemia, Wnt/β-catenin, MSC'
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Davis, Richard E., Vivian R. Ruvolo, Zhiqiang Wang, Wencai Ma, Wendy D. Schober, James Rolke, George Tidmarsh, Michael Andreeff, and Peter P. Ruvolo. "GCS-100 Induces Apoptosis of Acute Myeloid Leukemia Cells By Disrupting Galectin-Mediated Survival Signaling." Blood 124, no. 21 (December 6, 2014): 904. http://dx.doi.org/10.1182/blood.v124.21.904.904.
Full textTakam Kamga, Paul, Giada Dal Collo, Adriana Cassaro, Annalisa Adamo, Alessandro Gatti, Roberta Carusone, Mariano Di Trapani, et al. "Inhibition of GSK-3 Signalling Enhances Sensitivity of Non-Promyelocitic Acute Myeloid Leukemia (AML) Cell to Chemotherapy." Blood 128, no. 22 (December 2, 2016): 1582. http://dx.doi.org/10.1182/blood.v128.22.1582.1582.
Full textRoversi, Fernanda Marconi, Maura Lima Pereira Bueno, Rafael Gonçalves Barbosa Gomes, Guilherme Rossi Assis-Mendonça, Paulo Latuf Filho, Adriana Silva Santos Duarte, and Sara T. Olalla Saad. "A Novel WNT5A-Mimicking Peptide Affects Leukemia Cell Survival in the Bone Marrow Microenvironment." Blood 138, Supplement 1 (November 5, 2021): 2949. http://dx.doi.org/10.1182/blood-2021-148744.
Full textTakam Kamga, Paul, Adriana Cassaro, Giada Dal Collo, Annalisa Adamo, Alessandro Gatti, Roberta Carusone, Martina Midolo, et al. "Role of Wnt/β-Catenin Signalling in Acute Myeloid Leukemia (AML) Cell Response to Chemotherapy." Blood 128, no. 22 (December 2, 2016): 2753. http://dx.doi.org/10.1182/blood.v128.22.2753.2753.
Full textElyamany, Ghaleb, Hassan Rizwan, Ariz Akhter, Mansour S. Aljabry, Sultan Alotaibi, Mohammad A. Hameed Albalawi, Meer-Taher Shabani-Rad, Tariq Mahmood Roshan, and Adnan Mansoor. "“Losing the Brakes”—Suppressed Inhibitors Triggering Uncontrolled Wnt/ß-Catenin Signaling May Provide a Potential Therapeutic Target in Elderly Acute Myeloid Leukemia." Current Issues in Molecular Biology 45, no. 1 (January 9, 2023): 604–13. http://dx.doi.org/10.3390/cimb45010040.
Full textTakam Kamga, Paul, Giada Dal Collo, Adriana Cassaro, Riccardo Bazzoni, Pietro Delfino, Annalisa Adamo, Alice Bonato, et al. "Small Molecule Inhibitors of Microenvironmental Wnt/β-Catenin Signaling Enhance the Chemosensitivity of Acute Myeloid Leukemia." Cancers 12, no. 9 (September 21, 2020): 2696. http://dx.doi.org/10.3390/cancers12092696.
Full textMan, Cheuk Him, Tsz Kan Fung, Haixia Wan, Chae Yin Cher, August Fan, Nelson Ng, Christa Ho, et al. "Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia." Blood 125, no. 25 (June 18, 2015): 3928–36. http://dx.doi.org/10.1182/blood-2014-06-580993.
Full textZhuang, Lihui, Richard Darley, Oliver G. Ottmann, Joanna Zabkiewicz, and Caroline Alvares. "Bone Marrow Stromal Cells Mediate Adhesion Based Drug Resistance in Acute Myeloid Leukaemia through Reciprocal Feedback of the β-Catenin/CD44 Signalling Axis." Blood 132, Supplement 1 (November 29, 2018): 2776. http://dx.doi.org/10.1182/blood-2018-99-113811.
Full textZhang, Bin, Tinisha McDonald, Tessa L. Holyoake, Randall T. Moon, Dario Campana, Leonard Shultz, and Ravi Bhatia. "Microenvironmental Protection of CML Stem and Progenitor Cells From Tyrosine Kinase Inhibitors Through N-Cadherin and Wnt Signaling." Blood 120, no. 21 (November 16, 2012): 912. http://dx.doi.org/10.1182/blood.v120.21.912.912.
Full textMorgan, Rhys Gareth, Lorna Pearn, Kate Liddiard, Robert Hills, Alan Burnett, Alex Tonks, and Richard L. Darley. "Distinct Regulation of β- and γ-Catenin throughout Hematopoietic Development Contrasts with Their Cooperative Roles In Acute Myeloid Leukemia." Blood 116, no. 21 (November 19, 2010): 1573. http://dx.doi.org/10.1182/blood.v116.21.1573.1573.
Full textChai-Ho, Wanxing, Martina M. Roos, Michelle Li, Pang Amara, Yurun Zhang, Tiancheng Fang, Christina Termini, and John P. Chute. "Grb10 Is a Tumor Suppressor in Human Acute Myeloid Leukemia." Blood 132, Supplement 1 (November 29, 2018): 1344. http://dx.doi.org/10.1182/blood-2018-99-110844.
Full textHassan, Nunki, Hangyu Yi, Lucie Gaspard-Boulinc, Franklin Chen, Jayvee Datuin, Jonason Yang, and Jenny Yingzi Wang. "GADD45a Controls Self-Renewal in Acute Myeloid Leukemia Stem Cells." Blood 136, Supplement 1 (November 5, 2020): 31. http://dx.doi.org/10.1182/blood-2020-142389.
Full textHassan, Nunki, Basit Salik, Alastair Duly, and Jenny Yingzi Wang. "Rspo-LGR4 Cooperates with HOXA9 to Sustain Self-Renewal in Acute Myeloid Leukemia." Blood 134, Supplement_1 (November 13, 2019): 2669. http://dx.doi.org/10.1182/blood-2019-129704.
Full textAlmars, Amany, Panagiota S. Chondrou, Emenike K. Onyido, Sheema Almozyan, Claire Seedhouse, Roya Babaei-Jadidi, and Abdolrahman S. Nateri. "Increased FLYWCH1 Expression is Negatively Correlated with Wnt/β-catenin Target Gene Expression in Acute Myeloid Leukemia Cells." International Journal of Molecular Sciences 20, no. 11 (June 4, 2019): 2739. http://dx.doi.org/10.3390/ijms20112739.
Full textChai, Li, Wei Cui, Jianchang Chang, Chunhui Di, Hesham Amin, and Yupo Ma. "SALL4, a Novel Oncogene Induces Myelodysplastic Syndrome and Acute Myeloid Leukemia Via Wnt/β-Catenin Pathway." Blood 106, no. 11 (November 16, 2005): 1371. http://dx.doi.org/10.1182/blood.v106.11.1371.1371.
Full textWang, Lei, and Jie Jin. "The Mechanisms of Synergistically Cytotoxicity Induced by Homoharringtonine and Aclarubicin in Acute Myeloid Leukemia Cells." Blood 120, no. 21 (November 16, 2012): 4313. http://dx.doi.org/10.1182/blood.v120.21.4313.4313.
Full textTong, Hongyan, Kongfei Li, Chen Mei, Chao Hu, and Jie Jin. "Synergistic Effect of Sequential Combination of Decitabine and Idarubicin in Mouse Model of Human Acute Myeloid Leukemia." Blood 120, no. 21 (November 16, 2012): 1515. http://dx.doi.org/10.1182/blood.v120.21.1515.1515.
Full textJimbo, Koji, Takaaki Konuma, Takahiro Ito, Yaeko Nakajima-Takagi, Atsushi Iwama, and Arinobu Tojo. "Immunoglobulin Superfamily Member 8 Is Indispensable for Myeloid Leukemia Via Wnt/β-Catenin Signaling Pathway." Blood 136, Supplement 1 (November 5, 2020): 23–24. http://dx.doi.org/10.1182/blood-2020-136045.
Full textGriffiths, Elizabeth A., Craig M. Hooker, Michael A. McDevitt, Judith E. Karp, James G. Herman, and Hetty E. Carraway. "Acute Myeloid Leukemia Is Characterized by Wnt Pathway Inhibitor Promoter Methylation." Blood 112, no. 11 (November 16, 2008): 2253. http://dx.doi.org/10.1182/blood.v112.11.2253.2253.
Full textMoore, Amy C., Joseph M. Amann, Christopher S. Williams, Emilios Tahinci, Tiffany E. Farmer, J. Andres Martinez, Genyan Yang, K. Scott Luce, Ethan Lee, and Scott W. Hiebert. "Myeloid Translocation Gene Family Members Associate with T-Cell Factors (TCFs) and Influence TCF-Dependent Transcription." Molecular and Cellular Biology 28, no. 3 (November 26, 2007): 977–87. http://dx.doi.org/10.1128/mcb.01242-07.
Full textSayitoglu, Muge, Ozden Hatirnaz, Yucel Erbilgin, Fatmahan Atalar, and Ugur Ozbek. "Different Activation of WNT Signaling Pathway in B-Cell and T-Cell Acute Leukemias." Blood 108, no. 11 (November 16, 2006): 4317. http://dx.doi.org/10.1182/blood.v108.11.4317.4317.
Full textKode, Aruna, Sanil Manavalan, Ioanna Mossialou, Govind Bhagat, Murty Vundavalli, Ronald DePinho, Julie Teruya-Feldstein, Ellin Berman, and Stavroula Kousteni. "Leukemogenic Transformation of Hematopoietic Cells by Constitutive Activation of Canonical Wnt Signaling in Osteoblast Precursors." Blood 120, no. 21 (November 16, 2012): 509. http://dx.doi.org/10.1182/blood.v120.21.509.509.
Full textHu, Kaimin, Lizhen Liu, Binsheng Wang, Kangni Wu, Shan Fu, Yanjun Gu, Xiaoyu Lai, Xiaohong Yu, and He Huang. "Bone Marrow Mesenchymal Stromal Cells Protect Acute Lymphocytic Leukemia Cells From Cytotoxic Agents Via MAPK/Erk and Wnt/β-Catenin Signal Pathways." Blood 120, no. 21 (November 16, 2012): 4736. http://dx.doi.org/10.1182/blood.v120.21.4736.4736.
Full textTickenbrock, Lara, Joachim Schwäble, Markus Wiedehage, Björn Steffen, Bülent Sargin, Chunaram Choudhary, Christian Brandts, Wolfgang E. Berdel, Carsten Müller-Tidow, and Hubert Serve. "Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction." Blood 105, no. 9 (May 1, 2005): 3699–706. http://dx.doi.org/10.1182/blood-2004-07-2924.
Full textMüller-Tidow, Carsten, Björn Steffen, Thomas Cauvet, Lara Tickenbrock, Ping Ji, Sven Diederichs, Bülent Sargin, et al. "Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells." Molecular and Cellular Biology 24, no. 7 (April 1, 2004): 2890–904. http://dx.doi.org/10.1128/mcb.24.7.2890-2904.2004.
Full textCheng, Chi Keung, Libby Li, Suk Hang Cheng, Kitty Ng, Natalie P. H. Chan, Rosalina K. L. Ip, Raymond S. M. Wong, Matthew M. K. Shing, Chi Kong Li, and Margaret H. L. Ng. "Secreted-frizzled related protein 1 is a transcriptional repression target of the t(8;21) fusion protein in acute myeloid leukemia." Blood 118, no. 25 (December 15, 2011): 6638–48. http://dx.doi.org/10.1182/blood-2011-05-354712.
Full textLiu, Lin, Keyan Chen, Hua Fan, and Feng Jin. "MiR-599 regulates the activity of acute myeloid leukemia cells through MYC-mediated Wnt/β-catenin signaling." Annals of Translational Medicine 10, no. 3 (February 2022): 149. http://dx.doi.org/10.21037/atm-21-6852.
Full textJi, Hongyan, Li Chen, Yuqian Xing, Shanshan Li, Jianjian Dai, Ping Zhao, and Yulin Wang. "CD82 supports survival of childhood acute myeloid leukemia cells via activation of Wnt/β-catenin signaling pathway." Pediatric Research 85, no. 7 (March 12, 2019): 1024–31. http://dx.doi.org/10.1038/s41390-019-0370-3.
Full textLiu, Ye, Wei Wang, Yuan Li, and Yao Huang. "SOX30 confers a tumor suppressive effect in acute myeloid leukemia through inactivation of Wnt/β-catenin signaling." Molecular and Cellular Probes 52 (August 2020): 101578. http://dx.doi.org/10.1016/j.mcp.2020.101578.
Full textXin, Hong, Chengliang Li, and Minjuan Wang. "DIXDC1 promotes the growth of acute myeloid leukemia cells by upregulating the Wnt/β-catenin signaling pathway." Biomedicine & Pharmacotherapy 107 (November 2018): 1548–55. http://dx.doi.org/10.1016/j.biopha.2018.08.144.
Full textGolding, Michelle, Pragya Srivastava, Golda Collamat, Smitha R. James, Adam R. Karpf, Michael J. Nemeth, and Elizabeth A. Griffiths. "SGI-110, a Novel Hypomethylating Agent, Induces the WNT Inhibitor Secreted Frizzled Related Protein-2 (SFRP2), and Down Regulates β-Catenin in Acute Myeloid Leukemia (AML) Cells." Blood 120, no. 21 (November 16, 2012): 1290. http://dx.doi.org/10.1182/blood.v120.21.1290.1290.
Full textBraggio, Danielle Almeida, Fernanda Costas C. de Faria, David Koller, Feng Jin, Abeba Zewdu, Gonzalo Lopez, Kara Batte, et al. "Preclinical efficacy of the Wnt/β-catenin pathway inhibitor BC2059 for the treatment of desmoid tumors." PLOS ONE 17, no. 10 (October 14, 2022): e0276047. http://dx.doi.org/10.1371/journal.pone.0276047.
Full textSun, Clare, Christopher S. Seet, Jun Zhang, Yechen Xiao, Dewen You, and Jiwang Zhang. "FLT3 Signaling Enhances Stemness in Murine MLL-AF9 Acute Myeloid Leukemia." Blood 120, no. 21 (November 16, 2012): 2980. http://dx.doi.org/10.1182/blood.v120.21.2980.2980.
Full textLi, C., H. Xin, Y. Shi, and J. Mu. "Knockdown of TRIM24 suppresses growth and induces apoptosis in acute myeloid leukemia through downregulation of Wnt/GSK-3β/β-catenin signaling." Human & Experimental Toxicology 39, no. 12 (July 16, 2020): 1725–36. http://dx.doi.org/10.1177/0960327120938845.
Full textWu, Jun, Yingying Xie, and Limei Han. "miR-144-3p Derived from Bone Marrow Mesenchymal Stem Cells (BMSCs) Restrains the Drug Resistance of Acute Myeloid Leukemia (AML)." Journal of Biomaterials and Tissue Engineering 12, no. 8 (August 1, 2022): 1525–29. http://dx.doi.org/10.1166/jbt.2022.3065.
Full textGolding, Michelle, Benjamin E. Paluch, Pragya Srivastava, Song Liu, Qiang Hu, Meir Wetzler, Michael Nemeth, and Elizabeth A. Griffiths. "Patients Treated With Decitabine Demonstrate Changes In β-Catenin Localization From The Nucleus To The Cytoplasm In Circulating Blasts." Blood 122, no. 21 (November 15, 2013): 3956. http://dx.doi.org/10.1182/blood.v122.21.3956.3956.
Full textAgarwal, Puneet, Bin Zhang, Yinwei Ho, Amy Cook, Ling Li, Youzhen Wang, Margaret E. Mclaughlin, and Ravi Bhatia. "Inhibition of CML Stem Cell Renewal By the Porcupine Inhibitor WNT974." Blood 126, no. 23 (December 3, 2015): 54. http://dx.doi.org/10.1182/blood.v126.23.54.54.
Full textSakoda, Teppei, Yoshikane Kikushige, Toshihiro Miyamoto, and Koichi Akashi. "TIM-3/Gal-9 Signaling Enhances Self-Renewal Capacity of AML-LSCs through Mimicking Canonical Wnt Signaling." Blood 128, no. 22 (December 2, 2016): 1673. http://dx.doi.org/10.1182/blood.v128.22.1673.1673.
Full textDietrich, Philipp A., Murray D. Norris, and Jenny Yingzi Wang. "GPR84, a Proinflammatory Receptor, Sustains Wnt/β-Catenin Signaling In Leukemic Stem Cells For Maintenance Of MLL-AF9-Induced Leukemogenesis." Blood 122, no. 21 (November 15, 2013): 3781. http://dx.doi.org/10.1182/blood.v122.21.3781.3781.
Full textShahid, Akbar Muhammed, In Hwa Um, Mustafa Elshani, Ying Zhang, and David James Harrison. "NUC-7738 regulates β-catenin signalling resulting in reduced proliferation and self-renewal of AML cells." PLOS ONE 17, no. 12 (December 15, 2022): e0278209. http://dx.doi.org/10.1371/journal.pone.0278209.
Full textZhou, Hongsheng, Po Yee Mak, Hong Mu, Duncan H. Mak, Hiroyuki Kouji, Marina Konopleva, Jorge E. Cortes, Michael Andreeff, and Bing Z. Carter. "Combination of Tyrosine Kinase Inhibitor with β-Catenin/CBP Modulator C82 Reverses TKI Resistance, Eradicates Quiescent CML Stem/Progenitors Cells, and Overcomes MSC-Associated Microenvironmental Protection." Blood 124, no. 21 (December 6, 2014): 401. http://dx.doi.org/10.1182/blood.v124.21.401.401.
Full textYi, Hangyu, Jianlong Wang, Maria Kavallaris, and Jenny Yingzi Wang. "Lgr4-Mediated Potentiation Of Wnt/β-Catenin Signaling Promotes MLL Leukemogenesis Via An Rspo3/Wnt3a-Gnaq Pathway In Leukemic Stem Cells." Blood 122, no. 21 (November 15, 2013): 887. http://dx.doi.org/10.1182/blood.v122.21.887.887.
Full textJiang, Xuejie, Po Yee Mak, Hong Mu, Wenjing Tao, Duncan H. Mak, Steven Kornblau, Qi Zhang, et al. "Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3-Mutant Acute Myeloid Leukemia." Clinical Cancer Research 24, no. 10 (February 20, 2018): 2417–29. http://dx.doi.org/10.1158/1078-0432.ccr-17-1556.
Full textZhai, Hong, Junting Zhao, Juan Pu, Pan Zhao, and Jin Wei. "LncRNA-DUXAP8 Regulation of the Wnt/β-Catenin Signaling Pathway to Inhibit Glycolysis and Induced Apoptosis in Acute Myeloid Leukemia." Turkish Journal of Hematology 38, no. 4 (December 10, 2021): 264–72. http://dx.doi.org/10.4274/tjh.galenos.2021.2020.0769.
Full textWu, Shiwen, Dongqin Shen, and Li Zhao. "AKAP9 Upregulation Predicts Unfavorable Prognosis in Pediatric Acute Myeloid Leukemia and Promotes Stemness Properties via the Wnt/β-Catenin Pathway." Cancer Management and Research Volume 14 (January 2022): 157–67. http://dx.doi.org/10.2147/cmar.s343033.
Full textLi, Hongjiao, Chenglian Xie, Yurong Lu, Kaijing Chang, Feng Guan, and Xiang Li. "Exosomal miR92a Promotes Cytarabine Resistance in Myelodysplastic Syndromes by Activating Wnt/β-catenin Signal Pathway." Biomolecules 12, no. 10 (October 9, 2022): 1448. http://dx.doi.org/10.3390/biom12101448.
Full textIasenza, Isabella Angela, Safia Safa, Frederic Barabe, Sonia Cellot, Brian T. Wilhelm, and Kolja Eppert. "High-Throughput Chemical Screen on Acute Myeloid Leukemia Stem Cells Identifies Novel Anti-LSC Compounds." Blood 138, Supplement 1 (November 5, 2021): 1871. http://dx.doi.org/10.1182/blood-2021-145369.
Full textDaud, Siti Sarah, Alan K. Burnett, Richard L. Darley, and Alex Tonks. "Large-Scale Integration of Gene Profiling Identifies TCF7L2/TCF4 as the Most Frequently Dysregulated Wnt Signaling Component In AML." Blood 116, no. 21 (November 19, 2010): 2480. http://dx.doi.org/10.1182/blood.v116.21.2480.2480.
Full textBeghini, Alessandro. "Core Binding Factor Leukemia: Chromatin Remodeling Moves Towards Oncogenic Transcription." Cancers 11, no. 12 (December 7, 2019): 1973. http://dx.doi.org/10.3390/cancers11121973.
Full textAgarwal, Puneet, Bin Zhang, YinWei Ho, Amy Cook, Ling Li, Youzhen Wang, Margaret McLaughlin, and Ravi Bhatia. "Inhibition of CML Stem Cell Growth By Targeting WNT Signaling Using a Porcupine Inhibitor." Blood 124, no. 21 (December 6, 2014): 3130. http://dx.doi.org/10.1182/blood.v124.21.3130.3130.
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