Journal articles: 'Activité manipulatoire'

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Herman, P. "Evaluation of the reduction of dynamical coupling for robot manipulators." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 222, no. 3 (March 1, 2008): 339–47. http://dx.doi.org/10.1243/09544062jmes876.

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The problem of evaluation of the reduction of dynamical coupling in rigid serial manipulators is presented in the current paper. The proposed strategy is based on first-order equations of motion expressed in terms of normalized generalized velocity components, which result from decomposition of the manipulator mass matrix. The principal activity of the study relies on an algorithm in which some evaluation criteria as well as some indexes are used. The presented approach is important, mainly for manipulators with a direct drive arm at their design stage. Simulation results on a three-degree-of-freedom (3-DOF) spatial manipulator are given in order to illustrate the offered method.

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Konet, Andrii. "Modern Tools of Political Manipulation." Mediaforum : Analytics, Forecasts, Information Management, no. 7 (December 23, 2019): 235–49. http://dx.doi.org/10.31861/mediaforum.2019.7.235-249.

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The article proves that political manipulation is one of the conditions for the stable existence of political regimes and allows to control people and their consciousness. Tools and means of political manipulation are being continuously developed and improved, because they help political regimes function stably. Political manipulation is usually planned and organized, and can carry potential risks for the development of society as a whole. Political manipulators actively attract the media, which effectively distribute needed information and have the fullest impact on social consciousness. Peculiarities of political manipulation as a specific form of political influence, involve creating additional psychological levers of effective action in the process of the struggle for power. Political manipulators, with the help of various technologies of political manipulation, latently correct mass consciousness; include artificial stimulus (motivations) for action; redirect public moods and social activity in the direction they need. The author studies the current manifestations of political manipulation in the society: influence on public opinion; state authorities discredit; political advertising. To achieve success in the political struggle, the manipulator needs the support of society, which is guaranteed by the actions of mechanisms to influence public opinion. The author identifies and analyzes the following mechanisms of the means of political manipulation: language suggestion (speech influence), neuro-linguistic programming, and negative campaigning.

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Indri, Marina, Martina Bellissimo, Stefano Pesce, and Valerio Perna. "A Robust H∞ Application for Motor-Link Control Systems of Industrial Manipulators." Applied Sciences 12, no. 17 (September 5, 2022): 8890. http://dx.doi.org/10.3390/app12178890.

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H∞ control approaches are widely investigated in various application fields and in the robotics area, too, for their robustness properties. However, they are still rarely adopted in the industrial context for the control of robot manipulators, mainly due to the lack of predefined procedures to build weighting functions able to automatically guarantee the fulfillment of the control objectives. This paper reports the first results of an academic–industrial research activity aimed at investigating the adoption of an H∞ approach in the control software architecture of industrial manipulators, equipped with standard sensors on the motor side only. The design of the control system for a single-axis of an industrial manipulator is developed, showing that the construction of the weighting functions according to standard procedures can provide a satisfying behavior only on the motor side, leaving unacceptable oscillations of the link. A different procedure is then developed for the definition of the weighting functions with the specific aim of eliminating the possible vibrations of the mechanical structure. The proposed new form of such functions, including the main dynamic characteristics of the plant, ensures a robust, satisfying behavior on both the motor and the link side, as proven by simulation and experimental results.

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Miura, Satoshi, Yo Kobayashi, Kazuya Kawamura, Masatoshi Seki, Yasutaka Nakashima, Takehiko Noguchi, Yuki Yokoo, and Masakatsu G. Fujie. "Evaluation of Hand-Eye Coordination Based on Brain Activity." Journal of Advanced Computational Intelligence and Intelligent Informatics 19, no. 1 (January 20, 2015): 143–51. http://dx.doi.org/10.20965/jaciii.2015.p0143.

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Surgical robots have improved considerably in recent years, but their intuitive operability, and thus their user interoperability, has yet to be quantitatively evaluated. Thus, we propose a method for measuring a user’s brain activity while operating such a robot, to better enable the design of a robot with intuitive operability. The objective of this study was to determine the angle and radius between an endoscope and manipulator that best allows the user to perceive the manipulator as being part of their own body. In the experiments, a subject operated a hand controller to position the tip of a virtual slave manipulator onto a target in a surgical simulator while his/her brain activity was measured using a brain imaging device. The experiment was carried out several times with the virtual slave manipulator configured in a variety of ways. The results show that the amount of brain activity is significantly greater with a particular slave manipulator configuration. We concluded that the hand-eye coordination between the body image and the robot should be closely matched in the design of a robot having intuitive operability.

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Pavliv, Olha. "LINGUOPRAGMATIC ASPECTS OF MANIPULATIVE STRATEGIES IN THE SPEECH OF THE CHARACTERS OF A. MANZONI “BETROTHED”." PROBLEMS OF SEMANTICS, PRAGMATICS AND COGNITIVE LINGUISTICS, no. 43 (2023): 65–80. http://dx.doi.org/10.17721/2663-6530.2023.43.06.

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In the modern world, manipulation is a completely universal phenomenon. It can be found in all socially significant spheres of human activity. When studying manipulative strategies, it is impossible not to pay attention to the variety of their types and the goals through which manipulators resort to these actions. A set of manipulative techniques organized in a certain way, used for the purpose of exerting hidden influence, aimed at achieving a desired effect or preventing an undesirable result, is presented on examples taken from the historical novel by A. Manzoni "The Betrothed", in particular on the examples of the characters Gertrude, Don Abbondio, Lucia and Renzo. Manipulative strategies are widely used at the level of interpersonal communication. The variety of interpersonal manipulations is analyzed. Regularities between manipulative strategy and stylistic features have been established. In particular, to express the strategy of gaslighting, which is based on contradiction, the author uses affective words, asyndeton, tactics of exaggeration, repetition, and the imperative; to express projection, which consists in transferring one's responsibility to another person – metaphorical comparisons, antitheses; for the strategy of meaningless conversations, based on monologues that lead to confusion – incomplete sentences, repetitions, asyndeton; for generalization and denigration characterized by vague and abstract statements – incomplete sentences and affective words; to express the strategy of constant disappointment, which is based on the constant disappointment of the manipulator with his victim – asyndeton, exclamations, syntactic parallelism and repetitions. The perlocutionary effect, which is similar in each strategy, was studied. With his non-verbal behavior, the victim tries to convey discomfort and fear: trembling, lowered gaze, and therefore fear to look his manipulator in the eyes, silent submission. At the verbal level, this is manifested by repetitions, incomplete sentences, exclamations, exaggerations and affective words.

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Rofiq, M. N., W. Negara, S. Martono, R. A. Gopar, and M. Boga. "Potential effect of some essential oils on rumen methane reduction and digestibility by In Vitro incubation technique." IOP Conference Series: Earth and Environmental Science 905, no. 1 (November 1, 2021): 012138. http://dx.doi.org/10.1088/1755-1315/905/1/012138.

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Abstract Since excessive use of in-feed antibiotics and chemical feed supplements can potentially affect health risks and environmental problems, organic feed supplement became alternative save material. Organic material such as essential oils (EO) is potential for feed additive in the livestock industry because of their main activity as rumen manipulator. Their potential as rumen manipulators has not enough for type and doses of essential oils experiment. Therefore, the objective of this study was to evaluate 6 essential oils/EO’s (garlic/, thyme, clove, orange peel, mint, and cinnamon) with different doses (100, 200 and 300 ppm) on in vitro rumen methane reduction and in vitro digestibility using in vitro gas production technique. The experiment resulted highest level in in-vitro methane reduction potential (MRP, %) 72.83% at orange peel oils 300 ppm after 6 h incubation, while using clove oils 300 ppm had highest in vitro true digestibility of dry matter (IVTDDM) 81.41% after 30-hour incubation. Using Cinnamon oils had high value both of MRP level and IVTDDM (48.91 and 79.12 %). In Conclusion, all essential oils reduced in vitro rumen methane production at 6 h incubation compared to control at 300 ppm and there was no negative effect on In Vitro Digestibility.

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Sakamoto, Hironori, and Wataru Mitsuhashi. "Potential use of reproductive manipulators to control invasive alien ants." Terrestrial Arthropod Reviews 5, no. 3-4 (2012): 269–88. http://dx.doi.org/10.1163/18749836-05031053.

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Introduction of alien species is a worldwide problem that accompanies human activity. Invasive alien ants (Hymenoptera: Formicidae) are among those predatory invertebrates that cause the greatest damage to native ecosystems and biodiversity, and their management is difficult. Therefore, novel environmental load–reducing (i.e., highly invasive alien ant–specific) management methods are required. In this review, we present novel potential methods of invasive alien ant management that would use microorganisms to manipulate reproduction in the host arthropod. In general, reproductive manipulators force costs against their hosts during reproduction. However, most of the manipulators themselves incur no, or little, cost during the usual life of the host. Therefore, reproductive manipulators can be especially effective against social insects. For example, reproductive manipulators can decrease mating chance for males by killing or feminizing males. In addition, manipulators that induce parthenogenesis or cytoplasmic incompatibility (herein abbreviated CI) may be useful in new techniques for generating sterile males for release. Transinfection with reproductive manipulators by using microinjection techniques has recently become available. This strategy should be of great help in developing and applying this novel management method.

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Rivera, Robert Guamán, Rodrigo García Alvarado, Alejandro Martínez-Rocamora, and Fernando Auat Cheein. "A Comprehensive Performance Evaluation of Different Mobile Manipulators Used as Displaceable 3D Printers of Building Elements for the Construction Industry." Sustainability 12, no. 11 (May 27, 2020): 4378. http://dx.doi.org/10.3390/su12114378.

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The construction industry is currently technologically challenged to incorporate new developments for enhancing the process, such as the use of 3D printing for complex building structures, which is the aim of this brief. To do so, we show a systematic study regarding the usability and performance of mobile manipulators as displaceable 3D printing machinery in construction sites, with emphasis on the three main different existing mobile platforms: the car-like, the unicycle and the omnidirectional (mecanum wheeled), with an UR5 manipulator on them. To evaluate its performance, we propose the printing of the following building elements: helical, square, circular and mesh, with different sizes. As metrics, we consider the total control effort observed in the robots and the total tracking error associated with the energy consumed in the activity to get a more sustainable process. In addition, to further test our work, we constrained the robot workspace thus resembling real life construction sites. In general, the statistical results show that the omnidirectional platform presents the best results –lowest tracking error and lowest control effort– for circular, helicoidal and mesh building elements; and car-like platform shows the best results for square-like building element. Then, an innovative performance analysis is achieved for the printing of building elements, with a contribution to the reduction of energy consumption.

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Borisov, Vadim V., Andrey M. Sokolov, Anton P. Zharkov, and Oleg P. Kultygin. "Solving the inverse kinematics problem for sequential robot manipulators based on fuzzy numerical methods." Journal Of Applied Informatics 17, no. 4 (August 31, 2022): 113–26. http://dx.doi.org/10.37791/2687-0649-2022-17-4-113-126.

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Nowadays the introduction of robotic systems is one of the most common forms of the technological operations automation in various spheres of human activity. Among the robotic systems a special place is occupied by sequential multi-link robotic manipulators (SRM). SRM have become widespread due to relatively small dimensions and high maneuverability, which makes their use indispensable to solve various tasks. In practice, the effectiveness of the functioning of the SRM can be influenced by various types of external environment fuzzy factors. Among the external factors there is a group affecting the ability to determine the exact target position. Such factors often affect technical vision systems. This problem is especially relevant for special purpose mobile robots operating in aggressive environmental conditions. A situation similar to the described one also occurs when a medical robot manipulator is used for minimally invasive surgery, when the role of the control and monitoring system is assumed by an operator. In this regard, the organization of effective control taking into account influence of the external fuzzy factors, that prevent the correct recognition of the target position of the SRM instrument, is an urgent problem. The authors consider the solution of the inverse kinematics problem for SRM based on the use of fuzzy numerical methods, taking into account the possible occurrence of singular configurations in the process of solving.

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Miura, Satoshi, Yo Kobayashi, Kazuya Kawamura, Masatoshi Seki, Yasutaka Nakashima, Takehiko Noguchi, Masahiro Kasuya, Yuki Yokoo, and Masakatsu G. Fujie. "Intuitive Operability Evaluation of Robotic Surgery Using Brain Activity Measurements to Clarify Immersive Reality." Journal of Robotics and Mechatronics 25, no. 1 (February 20, 2013): 162–71. http://dx.doi.org/10.20965/jrm.2013.p0162.

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Surgical robots have undergone considerable improvement in recent years. But intuitive operability, which represents user interoperability, has not been quantitatively evaluated. With the aim of designing a robot with intuitive operability, we thus propose a method for measuring brain activity to determine intuitive operability. The purpose of this paper is to clarify the master configuration against the position of the monitor that best allows user to perceive the manipulator as part of his own body. We assume that the master configuration provides immersive reality to user as if he puts own arm into the monitor. In our experiments, subjects controlled the hand controller to position the tip of the virtual slave manipulator on a target in the surgical simulator and we measured brain activity using brain imaging devices. We carried out experiments a number of times with themastermanipulator configured in a variety of ways and the position of the monitor fixed. We found that the brain was significantly activated in all subjects when the master manipulator was located behind the monitor. We concluded that the master configuration produces immersive reality through body images related to visual and somatic sensory feedback.

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Zong, Li Jun, Guang Kuo Wang, Xin Li, Lei Wang, Xiao Min Zhang, Li Jia Wang, Ji Ming Dong, and Bai Wei Guo. "Trajectory Optimization and Simulation of Aerospace Robotic Arm." Advanced Materials Research 655-657 (January 2013): 1057–60. http://dx.doi.org/10.4028/www.scientific.net/amr.655-657.1057.

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Aerospace robotic arms have important applications in aerospace engineering (capture satellite, develop the technology of extra-vehicle activity (EVA), etc.) This paper first introduces the development and background of the Aerospace Robotic Arm. In later sections, a kinematics model of a Six-DOF manipulator is built based on DenavitHartenberg(D-H) method, then, the paper discusses an inverse kinematics solving method of the manipulator. At last, we show the simulation by integrating the use of SolidWorks, Matlab, and a number of their modules.

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Raviola, Andrea, Andrea De Martin, Roberto Guida, Giovanni Jacazio, Stefano Mauro, and Massimo Sorli. "Harmonic Drive Gear Failures in Industrial Robots Applications: An Overview." PHM Society European Conference 6, no. 1 (June 29, 2021): 11. http://dx.doi.org/10.36001/phme.2021.v6i1.2849.

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Industrial robots play a key role in production lines. As a direct consequence, even a slight degradation of their operating conditions could negatively affect the entire manufacturing process. To minimize economical losses, preventive measures such as planned maintenance or stand-by working stations are adopted and, in some cases, additional manipulators are installed to ensure line availability. However, since each robot performs a specific task, it degrades at a different rate from another one, so Planned Preventive Maintenance (PPM) should be replaced with Condition Based Maintenance (CBM) for a more efficient and cost-effective approach. In addition, collaborative robots (cobots) have become more and more popular in the past years increasing the level of automation, in particular in small and medium size companies. Therefore, a failure of an industrial manipulator could not only cause unexpected downtimes, but also jeopardize the safety of the personnel with whom it shares its workspace. A cobot, in fact, is labeled as safe as long as it works in nominal conditions, but this cannot be guaranteed otherwise. Within this framework, Prognostics and Health Management (PHM) techniques could be used for both a customized maintenance on a specific machine and for preventing undesired events like the aforementioned ones. An ongoing research activity at Politecnico di Torino is focused on a model-based approach able to better describe the behavior of an industrial robot in non-nominal operating conditions. In order to properly simulate faults and failures of a manipulator, it has been first necessary to analyze its failure modes and their impact on the entire system. A robot, in fact, is usually equipped with internal sensors and algorithms able to monitor its health status. However, this is only true for software or electrical failures (i.e. power supply, motor or sensors related), but it is not as effective in case of mechanical ones like bearings or gearbox wear. This paper firstly presents an overview of the possible failures related to harmonic drives which are often used in robotics due to their compact and light-weight design and the high reduction ratio. Then, it outlines the work done with the objective of providing an accurate, physics-based description of faults progression of harmonic drives used in industrial robots and the related high-fidelity models in the framework of a PHM system for fault and failure detection, isolation and remaining useful life (RUL) prediction.

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Yang, Na. "Remote Control of Manipulator Electronic System." Applied Mechanics and Materials 484-485 (January 2014): 391–95. http://dx.doi.org/10.4028/www.scientific.net/amm.484-485.391.

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With the continuous development of control technology, various areas of human activity, such as aviation, aerospace, exploration, production and other control techniques are demanding for increasingly higher requirements, one of which is on the remote control technology needs, especially remote control robot or facilities produced in accordance with the requirements to make certain human activities, productions and make them ordered to complete various tasks. We believe that with further improvement of automation technology and the advancement of human exploration, there will be more and more areas introduced to the remote control, and there will be new requirements for quality and performance of remote monitoring.

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Ericksen, Russell E., and Weiping Han. "Malignant manipulaTORs of metabolism: suppressing BCAA catabolism to enhance mTORC1 activity." Molecular & Cellular Oncology 6, no. 3 (March 20, 2019): 1585171. http://dx.doi.org/10.1080/23723556.2019.1585171.

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Chung, Cheng-Shiu, Hongwu Wang, Annmarie Kelleher, Dan Ding, and Rory Cooper. "Daily Activity Performance Evaluation of Commercial Assistive Robotic Manipulator User Interfaces." Archives of Physical Medicine and Rehabilitation 98, no. 10 (October 2017): e20. http://dx.doi.org/10.1016/j.apmr.2017.08.062.

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Yamazaki, Kimitoshi, Kazuki Nogami, and Kotaro Nagahama. "Viewpoint Planning for Object Identification Using Visual Experience According to Long-Term Activity." International Journal of Automation Technology 16, no. 2 (March 5, 2022): 197–207. http://dx.doi.org/10.20965/ijat.2022.p0197.

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In this paper, we propose a viewpoint planning method for object identification. We introduce the policy of maximizing the posterior probability of the orientation of an object observed after a robot moves its viewpoint and show a novel formulation of viewpoint planning. In addition, we propose criteria for viewpoint selection based on past sensing experience. Finally, we confirm the effectiveness of the proposed method via simulations using a mobile manipulator.

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Vlăduţescu, Ştefan. "Actants of Manipulative Communication." International Letters of Social and Humanistic Sciences 40 (September 2014): 41–47. http://dx.doi.org/10.18052/www.scipress.com/ilshs.40.41.

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The study starts from assumption that together with disinfomation, intoxication, and propaganda, the manipulation is a form of persuasion, a form of persuasive communication. The manipulation is a communicative action. By the way of meta-analytical method, we emphasize some ideas. The royal way of promoting the decisive interests is manipulation-, often accompanied by constraints and violence. The world is divided into amateur manipulators and professional manipulators. Professionals are those whose job is exactly to get something from the others. The action of manipulation is not an activity performed on inspiration, randomly and by ear. Manipulation is a structured, organised and planned persuasive intervention. As actants of manipulative communication are retained journalists, priests, businessmen, sellers, scholars, teachers, artists, writers, notabilities.

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Cao, Tianao, Dan Liu, Qisong Wang, Ou Bai, and Jinwei Sun. "Surface Electromyography-Based Action Recognition and Manipulator Control." Applied Sciences 10, no. 17 (August 22, 2020): 5823. http://dx.doi.org/10.3390/app10175823.

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To improve the quality of lives of disabled people, the application of intelligent prosthesis was presented and investigated. In particular, surface Electromyography (sEMG) signals succeeded in controlling the manipulator in human–machine interface, due to the fact that EMG activity belongs to one of the most widely utilized biosignals and can reflect the straightforward motion intention of humans. However, the accuracy of real-time action recognition is usually low and there is usually obvious delay in a controlling manipulator, as a result of which the task of tracking human movement precisely, cannot be guaranteed. Therefore, this study proposes a method of action recognition and manipulator control. We built a multifunctional sEMG detection and action recognition system that integrated all discrete components. A biopotential measurement analog-to-digital converter with a high signal–noise rate (SNR) was chosen to ensure the high quality of the acquired sEMG signals. The acquired data were divided into sliding windows for processing in a shorter time. Mean Absolute Value (MAV), Waveform Length (WL), and Root Mean Square (RMS) were finally extracted and we found that compared to the Genetic-Algorithm-based Support Vector Machine (GA–SVM), the back propagation (BP) neural network performed better in joint action classification. The results showed that the average accuracy of judging the 5 actions (fist clenching, hand opening, wrist flexion, wrist extension, and calling me) was up to 93.2% and the response time was within 200 ms, which achieved a simultaneous control of the manipulator. Our work took into account the action recognition accuracy and real-time performance, and realized the sEMG-based manipulator control eventually, which made it easier for people with arm disabilities to communicate better with the outside world.

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Kartashev, V. A., and V. V. Kartashev. "Emergency Braking Trajectory Control for Manipulator in the Case of Driver Failure." Mekhatronika, Avtomatizatsiya, Upravlenie 21, no. 1 (January 14, 2020): 28–33. http://dx.doi.org/10.17587/mau.21.28-33.

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In emergency situation robot control system stops the manipulator by shutdowning drivers and activating brakes. This mode is used in all cases of equipment failure detection or while alarm bottom is pressed on control panel. Emergency braking is uncontrolled motion. As result manipulator movement deviates from program trajectory as the relations between velocities in joints differ significantly. This creates danger of collisions with objects in robot work space. The paper describes device that can be connected to control system. Connection needs insignificant changing in hardware architecture of robot control system. Device consists of controller and individual electronic schemes that are able to activate brakes of each degree of freedom regardless from other one. This feature allows to design braking trajectory by activating brakes in specific sequence and calculated delays. Mathematical solution for deviation minimization problem of braking trajectory from program one is presented. The solution is reduced to mathematical formulas which depend of the temporary velocities and values of braking decelerations in manipulator joints. The considered way of control differs from similar one described earlier by that in emergency situation drivers turn off immediately. On the first stage manipulator brakes by friction forces in gear boxes. Theoretical evaluations show that in all cases this reduces deviations from program trajectory. Additionally the new way can be used even if fault takes place at least one of drivers.

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Kimura, Shinichi, Meguru Yamauchi, and Yoshihiro Ozawa. "Magnetically Jointed Module Manipulators: New Concept for Safe Intravehicular Activity in Space Vehicles." IEEE Transactions on Aerospace and Electronic Systems 47, no. 3 (July 2011): 2247–53. http://dx.doi.org/10.1109/taes.2011.5937298.

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Samborski, Tomasz, Jan Wiejak, and Eugeniusz Matras. "Device for Low-Cost Assembly of Chips in RFID Inlays." Solid State Phenomena 237 (August 2015): 239–44. http://dx.doi.org/10.4028/www.scientific.net/ssp.237.239.

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Security systems employ the RFID method to protect objects and data and to ensure public safety and the safety of commercial activity, e.g. through the control over technological processes. The research activity aimed at improving the level of safety of electronic and technical protection needs to be verified through the manufacture of prototype IDs with RFID inlays.The authors presents an original experimental device enabling the implementation of individual chips in RFID inlays, which were made on a flexible base to which an RFID antenna is attached. The collection of the chip from the dispenser and an unambiguous orientation of the soldered tips in relation to the antenna are provided by a four-axis vacuum manipulator cooperating with a vision system identifying the location of the chip on the manipulator and its final application area. A computer control system enables the operation in two modes, i.e. a semi-automatic mode in which it is possible to manually control the order and the way in which individual tasks are performed, and an automatic mode conducted according to the designed algorithm. The developed device is intended for research on the ways to improve the manufacturing techniques and electronic document protection by means of RFID technologies.

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Smith, Philip, Rosie E. Fallon, Niamh E. Mangan, Caitriona M. Walsh, Margarida Saraiva, Jon R. Sayers, Andrew N. J. McKenzie, Antonio Alcami, and Padraic G. Fallon. "Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity." Journal of Experimental Medicine 202, no. 10 (November 21, 2005): 1319–25. http://dx.doi.org/10.1084/jem.20050955.

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The coevolution of humans and infectious agents has exerted selective pressure on the immune system to control potentially lethal infections. Correspondingly, pathogens have evolved with various strategies to modulate and circumvent the host's innate and adaptive immune response. Schistosoma species are helminth parasites with genes that have been selected to modulate the host to tolerate chronic worm infections, often for decades, without overt morbidity. The modulation of immunity by schistosomes has been shown to prevent a range of immune-mediated diseases, including allergies and autoimmunity. Individual immune-modulating schistosome molecules have, therefore, therapeutic potential as selective manipulators of the immune system to prevent unrelated diseases. Here we show that S. mansoni eggs secrete a protein into host tissues that binds certain chemokines and inhibits their interaction with host chemokine receptors and their biological activity. The purified recombinant S. mansoni chemokine binding protein (smCKBP) suppressed inflammation in several disease models. smCKBP is unrelated to host proteins and is the first described chemokine binding protein encoded by a pathogenic human parasite and may have potential as an antiinflammatory agent.

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Mehta, Divyesh G., and Radhika A. Vaishnav. "If tumor changes the tune, we change the music." International Journal of Molecular and Immuno Oncology 3, no. 3 (October 26, 2018): 67. http://dx.doi.org/10.18203/issn.2456-3994.intjmolimmunooncol20184339.

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<p>Last decade saw arrival of Immunotherapies and dramatic advances with PD inhibitor and CLTA4 manipulators. Now come dramatic reports of Adaptive Cell Technology, a treatment using patients own lymphocytes with anti tumor activity, expanded in vitro and reinfused. Recently, in a new clinical trial by Zakaris et al, a 49 year old patient with ER positive and ERBB2 tyrosine kinase 2 negative metastatic breast cancer that was no longer responsive to other treatments was reported to show complete regression of the cancer using Adaptive Cell Technology. </p>

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Na, Liu, Oleksandr Gerasin, Andrіy Topalov, and Anton Karpechenko. "ANALYSIS OF TASKS OF MONITORING AND AUTOMATIC CONTROL OF AGRICULTURAL MOBILE ROBOT." Management of Development of Complex Systems, no. 47 (September 27, 2021): 174–79. http://dx.doi.org/10.32347/2412-9933.2021.47.174-179.

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The work is devoted to the consideration and analysis of a set of tasks of monitoring and automatic control of modern mobile robots, designed for automation of various types of technological operations in agriculture. Studies indicate high activity of manufacturing companies and scientists in the development of structures and remote control systems for various types of agricultural robots due to the general increase in demand for food in conditions of limited unleavened water reserves, high prices for mineral fertilizers and wages of the staff. The paper presents the classification of modern agricultural robots according to the degree of mobility, type of control system, working environment, industry and functional purpose. It is determined, that such robots are equipped with built-in development boards with microcontrollers or microprocessors, which everyone has on board, regardless of the design and type of the control system. In addition, remote control methods and tools are most often used to automate agricultural works, but automatic and autonomous mobile robots independently perform a much wider list of tasks, because they work on the basis of adaptive-intelligent control methods. The authors formulate the main tasks of monitoring and automatic control for the generalized agricultural mobile robot, in particular monitoring and automatic control of vectors of spatial motion parameters, operating parameters of technical equipment of movers, manipulators, gripping devices, as well as parameters of specified agricultural works and operations. The functional structure of the generalized agricultural mobile robot as a multi-coordinate control object, which takes into account the interaction of controlled coordinate vectors, control signals of propulsors, manipulators, grippers and process equipment, as well as perturbing effects on its individual components (body, propulsions, manipulators, gripping devices and technological equipment) is proposed in the paper.

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Pástor, Miroslav, Martin Hagara, Štefan Gašpár, and Milan Sapieta. "Design and Implementation of a Low-Cost Torque Sensor for Manipulators." Applied Sciences 13, no. 16 (August 18, 2023): 9406. http://dx.doi.org/10.3390/app13169406.

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Humanoid and collaborative robots find their application in numerous sectors, such as automotive, electrical and mechanical engineering, not excluding the field of bioengineering. They replace repetitive and often monotonous human activity. As the trend nowadays is for continuous optimization of production processes, their advantage is easy relocation and operative application to new tasks, which allows the automation of practically all manual work. A common feature of manipulators is the control of the positioning of the actuators, primarily by adjusting the parameters of the drive units. Feedback is often implemented through various sensors that provide real-time information. However, most of the sensors in use do not provide information that would allow obtaining data on the history of the operating load in order to assess the further safe and reliable operation of the mechanical parts. This paper presents a low-cost torque sensor that was proposed by modifying the design of an existing part. The torque sensor was developed on the principle of strain gauge measurement. The results of strain–stress analysis obtained by numerical modelling were experimentally validated under static and dynamic loading. Practical application is mainly the development and long-term testing of prototypes of various types of manipulators and collaborative robots, where high accuracy and repeatability of positioning are essential.

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Ramasubramanian, Aswin K., Syed M. Aiman, and Nikolaos Papakostas. "On using human activity recognition sensors to improve the performance of collaborative mobile manipulators: Review and outlook." Procedia CIRP 97 (2021): 211–16. http://dx.doi.org/10.1016/j.procir.2020.05.227.

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Brayshaw, George, Benjamin Ward-Cherrier, and Martin J. Pearson. "Simultaneous Velocity and Texture Classification from a Neuromorphic Tactile Sensor Using Spiking Neural Networks." Electronics 13, no. 11 (June 1, 2024): 2159. http://dx.doi.org/10.3390/electronics13112159.

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The neuroTac, a neuromorphic visuo-tactile sensor that leverages the high temporal resolution of event-based cameras, is ideally suited to applications in robotic manipulators and prosthetic devices. In this paper, we pair the neuroTac with Spiking Neural Networks (SNNs) to achieve a movement-invariant neuromorphic tactile sensing method for robust texture classification. Alongside this, we demonstrate the ability of this approach to extract movement profiles from purely tactile data. Our systems achieve accuracies of 95% and 83% across their respective tasks (texture and movement classification). We then seek to reduce the size and spiking activity of our networks with the aim of deployment to edge neuromorphic hardware. This multi-objective optimisation investigation using Pareto frontiers highlights several design trade-offs, where high activity and large network sizes can both be reduced by up to 68% and 94% at the cost of slight decreases in accuracy (8%).

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J Gambhire, Shankar, D. Ravi Kishore, Malligunta Kiran Kumar, and Sushant N Pawar. "Design of Super Twisting Integral Sliding Mode Control for Industrial Robot Manipulator." International journal of electrical and computer engineering systems 13, no. 9 (December 6, 2022): 815–21. http://dx.doi.org/10.32985/ijeces.13.9.10.

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In the present work, integral sliding mode based continuous control algorithm is extended to multi input multi output system. The typical integral sliding mode control (ISMC) contains nominal control with discontinuous feedback control due to which overall control becomes discontinuous in nature. The proposed controller is a fusion of two continuous terms and one of which is able to handle, estimate and reject the disturbance successfully. A proposed robust ISMC technique is applied for industrial robot manipulators which utilizes interactive manipulation activity. Here, robust position tracking control obtained via ISMC principle for two link IRM scheme influenced by parametric uncertainties and external disturbances. The proposed ISMC design replaces the discontinuous part by continuous control, which super twisting control is able to handle the disturbance rejection completely. The effectiveness of the proposed control technique is tested under uncertain conditions and comparison study with other controllers has been done. The simulation result shows that the tracking error is effectively minimized by the proposed technique in presence of uncertain conditions.

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Aknouch, Adil, Youssef El-ouardi, Mohammed Mouhib, Rajaa Sebihi, and Abdelmajid Choukri. "Radiation protection study for a reloading operation of cobalt 60 sources in the Moroccan ionisation station using the GEANT4 Monte-Carlo simulation code." E3S Web of Conferences 234 (2021): 00007. http://dx.doi.org/10.1051/e3sconf/202123400007.

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The operation of reloading the irradiators is considered among the tasks requiring high radiation protection monitoring, to protect the intervening manipulators, the public and the environment. Morocco is among the countries that have a cobalt irradiator, installed at the National Institute of Agricultural Research (NIAR) of Tangier, to carry out research in the field of agronomy. In the beginning, the irradiator used low doses of activity for the study of products only, for treatment of high doses. The NIAR carried out a reload to increase the activity. To perform this, a temporary pool was installed inside the irradiation room to handle the sources safely. A radiation protection study is necessary to ensure the safe operation. This operation requires a height level of exposure. To ovoid the exposer risk, it is proposed to use the Monte Carlo method thanks to its reliability in the dosimetric calculation. This article presents a radiation protection study of the Moroccan irradiator reloading operation using the GEANT4 Monte-Carlo Simulation Code.

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Pritykin, Fedor Nikolaevich, and Valeriy Ivanovich Nebritov. "Design of linear surfaces that restrict the range of permissible positions of links of the manipulator mechanisms in implementation of instantaneous states." Программные системы и вычислительные методы, no. 2 (February 2021): 74–90. http://dx.doi.org/10.7256/2454-0714.2021.2.35574.

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Linear surfaces are used in various spheres of human activity. One of the most common techniques of designing linear surfaces is based on the three directing curves. In some cases, one of these directing curves is not set, but rather replaced by some geometric condition imposed on the emerging surfaces, which can in form of a certain point correspondence established between the points of the rest two directing curves. The article reviews the example of designing such surfaces, which in an approximate form would restrict the zone that sets the permissible positions of links of the manipulator mechanism of certain given configuration in realization of permissible instantaneous states. The acquired linear surfaces underlie the algorithm for calculation of configurations, which do not intersect the restricted zone in case of a deadlock situation. The result of this research is the computer simulation of the motions of arm and torso mechanism of the Android robot using the obtained algorithm for calculation of configurations. The simulation of motion demonstrates that the use of linear surfaces in analysis of the relative position of the manipulator and restricted zones in the deadlock situations allows reducing the calculation time by 50-60 percent. Such reduction of calculation time is highly demanded in computer control of the arm and torso motions of the Android robot on a real time scale.

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Lytkin, S. D., and F. S. Lytkin. "FROM THE EXPERIENCE OF USING COMPUTER VISION AND MANIPULATOR IN THE PROJECT ACTIVITY OF A SCHOOLER IN ROBOTICS." Современные проблемы науки и образования (Modern Problems of Science and Education), no. 6 2021 (2021): 29. http://dx.doi.org/10.17513/spno.31256.

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Fagundes, G. M., G. Benetel, K. C. Santos, K. C. Welter, F. A. Melo, J. P. Muir, and I. C. S. Bueno. "Tannin-Rich Plants as Natural Manipulators of Rumen Fermentation in the Livestock Industry." Molecules 25, no. 12 (June 26, 2020): 2943. http://dx.doi.org/10.3390/molecules25122943.

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Condensed tannins (CTs) are plant anti-herbivore compounds with antimicrobial activity that can be used in ruminant diets as ruminal microbiome manipulators. However, not all CTs from fodder legumes are bioactive due to their wide structural diversity. The aim of our study was to investigate the effect of 10 CT-containing plants (Flemingia macrophylla, Leucaena leucocephala, Stylosanthes guianensis, Gliricidia sepium, Cratylia argentea, Cajanus cajan, Desmodium ovalifolium, Macrotiloma axilare, D. paniculatum, and Lespedeza procumbens) on in vitro fermentation kinetics of Nelore beef cattle. Polyethylene glycol (PEG), a specific CT-binding agent, was added to neutralize condensed tannin. Tifton and alfalfa hay were used as controls lacking CT. The experimental layout included a randomized complete block with factorial design and four blocks. The data were subjected to analysis of variance followed by Duncan’s test to determine differences (p < 0.05) among treatment means. The addition of PEG in browse incubations resulted in increased gas production, fermentation rate, short-chain fatty acid (SCFA) and N-NH3 release. Within our study, Lespedeza procumbens, Desmodium paniculatum, Leucaena leucocephala, Desmodium ovalifolium, and Flemingia macrophylla showed superior bioactivity compared to other species evaluated, suggesting a natural alternative for replacing ionophores to modify ruminal fermentation. Condensed tannins from L. pocumbens, D. paniculatum, L. leucocephala, D. ovalifolium, and F. macrophylla have the potential to modify rumen fermentation in beef cattle.

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MAEKAWA, Shouta, Kazuhiko TAKAHASHI, and Masafumi HASHIMOTO. "J1630102 Remarks on Brain Activity Recognition from a Compact NIRS using Fuzzy Reasoning with Application to Controlling Robot Manipulator." Proceedings of Mechanical Engineering Congress, Japan 2014 (2014): _J1630102——_J1630102—. http://dx.doi.org/10.1299/jsmemecj.2014._j1630102-.

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Bennett, Gregg. "Students’ Participation Styles in Two University Weight Training Classes." Journal of Teaching in Physical Education 19, no. 2 (January 2000): 182–205. http://dx.doi.org/10.1123/jtpe.19.2.182.

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The purpose of this study was to describe the participation styles of students enrolled in two basic instruction weight training classes. The students’ participation styles fell somewhere on a continuum between slackin’ and sweatin’. Through the use of class observations and interviews with the students and the instructors, six styles of participation were identified within both of these categories. Four participation styles were revealed in the slackin’ category. These were (a) socializers, (b) manipulators, (c) underachievers, and (d) minimalists. The two styles identified in the sweatin’ category were (a) sidekicks and (b) ex-athletes. The transtheoretical model for behavior modification was used to describe the students’ activity levels in the classes and predict exercise adherence among the twelve participants. Further in-depth studies are needed to assess the state of basic instruction program classes within individual programs and classes throughout the nation.

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Camps, Assumpta. "LA TRADUCCIÓN EN LAS RELACIONES ENTRE ORIENTE Y OCCIDENTE: EL CASO DE MAHATMA GANDHI." TRANSFER 4, no. 2 (September 25, 2017): 1–12. http://dx.doi.org/10.1344/transfer.2009.4.1-12.

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Translation is one of the most important channels in the diffusion of an author and his/her work in other cultures and literatures. It is essential when considering his/her reception, and specially when dealing between very distant cultures like in Eastern-Western relationships. Translation is always relevant in the image of a certain author abroad, since it is never a neutral and innocent activity, but a highly manipulatory one through the mediation process that it implies. From that point of view, the aim of this paper is to analyse the reception of Mahatma Gandhi in one of the most widely spoken languages in the world, that is Spanish, through the translations of his writings published in that language both for the Spanish and the Latin American audiences, as a contribution to the study of Gandhi's influence in the world literature.

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Cater, John P., and Stephen D. Huffman. "Use of the Remote Access Virtual Environment Network (RAVEN) for Coordinated IVA—EVA Astronaut Training and Evaluation." Presence: Teleoperators and Virtual Environments 4, no. 2 (January 1995): 103–9. http://dx.doi.org/10.1162/pres.1995.4.2.103.

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This paper presents a unique virtual reality training and assessment tool developed under a NASA grant, “Research in Human Factors Aspects of Enhanced Virtual Environments for Extravehicular Activity (EVA) Training and Simulation.” The Remote Access Virtual Environment Network (RAVEN) was created to train and evaluate the verbal, mental, and physical coordination required between the intravehicular (IVA) astronaut operating the Remote Manipulator System (RMS) arm and the EVA astronaut standing in foot restraints on the end of the RMS. The RAVEN system currently allows the EVA astronaut to approach the Hubble Space Telescope (HST) under control of the IVA astronaut and grasp, remove, and replace the Wide Field Planetary Camera drawer from its location in the HST. Two viewpoints, one stereoscopic and one monoscopic, were created all linked by Ethernet, that provided the two trainees with the appropriate training environments.

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Repousis, Spyridon. "Using Beneish model to detect corporate financial statement fraud in Greece." Journal of Financial Crime 23, no. 4 (October 3, 2016): 1063–73. http://dx.doi.org/10.1108/jfc-11-2014-0055.

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Purpose This paper aims to investigate empirically the eight-variables Beneish M-model to identify occurrence of financial statement fraud or tendency to engage in earning manipulation. Design/methodology/approach A data set of 25,468 companies (Société Anonyme and Limited Liability Companies) in Greece was analyzed during two-year period of 2011-2012. Financial statements of banks are excluded. Findings The results showed that 8,486 companies or 33 per cent of the whole sample has a greater than −2.2 score, which is a signal that companies are likely to be manipulators. Also, for manipulators, results using F-distribution showed that days sales in receivable index (DSRI), asset quality index (AQI), depreciation index, selling, general and administrative expenses index (SGAI), total accruals to total assets index and leverage index (LVGI) are significant at 99 per cent confidence level in its effect on Beneish M-score. Also, there is a significant relationship between earning management, as expressed by Beneish M-score and each one of variables, DSRI, AQI, gross margin index, sales growth index, SGAI and LVGI. Most of all, DSRI explains 95.92 per cent of the variation in Beneish M-score in statistical terms. Practical implications Results are important for banking system, because financial statements information influence credit decisions of banks. Debt agreements include terms based upon accounting numbers. Also, using Beneish Model, it is a cheap and easy way for examiners of possible fraudulent activity. Originality/value To the best of the author’s knowledge, there is a great lack of research in Greece, using Beneish model. There is only one more study using the Beneish model, examining only a few companies listed in Athens Stock Exchange during 1999-2000. Findings have also important implications not only for banks but also for users of Greek financial statement accounts, especially to investors, auditors, regulators, to taxation and other state authorities.

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Kinyasheva, Yulia B., and Sergei V. Murashchenkov. "SOCIO-POLITICAL RISKS OF CIVIC PARTICIPATION OF THE RUSSIAN YOUTH IN THE CONDITIONS OF DIGITALIZATION OF SOCIETY." RSUH/RGGU Bulletin. Series Political Sciences. History. International Relations, no. 3 (2023): 108–21. http://dx.doi.org/10.28995/2073-6339-2023-3-108-121.

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The article considers online forms of civic participation of young people in the digital space, aimed at protecting their rights, expressing political positions, demonstrating attitude to decisions made by authorities. Oftentimes the civic activity of young people goes beyond social tasks and issues (volunteering, participation in social projects, etc.), becomes politicized due to the dependence of many decisions on the authorities. Therefore, the article considers civic participation in relation to the political activity of young people. It is proved that excessive freedom of action and lack of control in social media, the availability of various information channels, a decrease in trust and loyalty to official sources of information, create a zone of socio-political risks of the manifestation of the protest civic activity of young people, which falls under the influence of manipulators (influencers) and intensifies both online and offline formats. During the expert survey, it was found that as a result of online communication, content, communicational, electronic and ideological sociopolitical risks manifest themselves. The risks may produce consequences which may be destructive actions on the part of young citizens in social networks (criticism, condemnation, bullying, disinformation, aggression, etc.) against the political system. Due to the adoption of timely institutional measures, it is possible to manage the digital space, and in particular, the socio-political risks of civic participation of young people in modern Russia

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Liu, Quan, Mengnan Li, Chaoyue Yin, Guoming Qian, Wei Meng, Qingsong Ai, and Jiwei Hu. "CNN-Based Hand Grasping Prediction and Control via Postural Synergy Basis Extraction." Sensors 22, no. 3 (January 22, 2022): 831. http://dx.doi.org/10.3390/s22030831.

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The prediction of hand grasping and control of a robotic manipulator for hand activity training is of great significance to assist stroke patients to recover their biomechanical functions. However, the human hand and the figure joints have multiple degrees of freedom; therefore, it is complex to process and analyze all the collected data in hand modeling. To simplify the description of grasping activities, it is necessary to extract and decompose the principal components of hand actions. In this paper, the relationships among hand grasping actions are explored by extracting the postural synergy basis of hand motions, aiming to simplify hand grasping actions and reduce the data dimensions for robot control. A convolutional neural network (CNN)-based hand activity prediction method is proposed, which utilizes motion data to estimate hand grasping actions. The prediction results were then used to control a stimulated robotic model according to the extracted postural synergy basis. The prediction accuracy of the proposed method for the selected hand motions could reach up to 94% and the robotic model could be operated naturally based on patient’s movement intention, so as to complete grasping tasks and achieve active rehabilitation.

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Zhuravin, I. A., N. N. Nalivaeva, S. A. Plesneva, N. M. Dubrovskaya, U. B. Chekulaeva, and B. I. Klement'ev. "Activity of adenylate cyclase and 5′-nucleotidase in the sensorimotor and limbic structures of the brain in rats after manipulatory training." Neuroscience and Behavioral Physiology 26, no. 6 (November 1996): 552–57. http://dx.doi.org/10.1007/bf02359498.

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Bajtalyuk, A. A., A. V. Adrianov, V. N. Akulin, I. V. Dyujzen, M. Y. Kuznetsov, and Y. A. Kuznetsov. "Experimental ground for interdisciplinary marine biotechnology science as an effective solution tool for existing problems in fishing industry." Trudy VNIRO 181 (2020): 16–32. http://dx.doi.org/10.36038/2307-3497-2020-181-16-32.

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In 2018, in the Scientific and Educational Complex “Primorsky Oceanarium” of the National Scientific Center for Marine Biology (NSCMB) FEB RAS, a Collective Use Center (CUC) was created with scientific equipment, coastal and near-shore infrastructure, unique facilities and biological materials. In its function, this Center is a unit for cooperation between fishery science and academic science in marine biotechnology (MBC). It was organized using principles of shared access of participants to marine areas, coastal research stations, biological and instrumental basis of Marine Mammals Research facility in “Primorsky Oceanarium” MBC structure in the form of CUC can be used in addressing a wide range of tasks in implementing knowledge intensive marine biotechnologies, upgrading bionic methods in the study of aquatic organisms, carrying out field studies and tests on hydroacoustic, electrical, fishing gear and other manipulators for moving behavior of aquatic organisms and their adaptation to fishing activity. The first MBC joint research results are shown. Those studies include research on acoustic and kinematic activity and characteristics of signals of marine mammals and fish, hydroacoustic emitters testing for controlling fish behavior, experimental studies on reflective properties of aquatic irganisms, and influence of attracting and repelling hydroacoustic emitters on fish behavior in cages using modern instrumental control and observation tools.

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WATANABE, Keisuke, Atsushi UETA, Yuto TAKEI, and Shin'ichiro NISHIDA. "2P1-M03 Development of an Arm Component of the Attachable Manipulator for Supporting Extra Vehicular Activity(Space Engineering and Robotics and Mechatronics)." Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2013 (2013): _2P1—M03_1—_2P1—M03_2. http://dx.doi.org/10.1299/jsmermd.2013._2p1-m03_1.

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Mösenlechner, Lorenz, and Michael Beetz. "Using Physics- and Sensor-based Simulation for High-Fidelity Temporal Projection of Realistic Robot Behavior." Proceedings of the International Conference on Automated Planning and Scheduling 19 (October 16, 2009): 249–56. http://dx.doi.org/10.1609/icaps.v19i1.13357.

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Planning means deciding on the future course of action based on predictions of what will happen when an activity is carried out in one way or the other. As we apply action planning to autonomous, sensor-guided mobile robots with manipulators or even to humanoid robots we need very realistic and detailed predictions of the behavior generated by a plan in order to improve the robot's performance substantially.In this paper we investigate the high-fidelity temporal projection of realistic robot behavior based on physics- and sensor-based simulation systems. We equip a simulator and interpreter with means to log simulated plan executions into a database. A logic-based query and inference mechanism then retrieves and reconstructs the necessary information from the database and translates the information into a first-order representation of robot plans and the behavior they generate. The query language enables the robot planning system to infer the intentions, the beliefs, and the world state at any projected time. It also allows the planning system to recognize, diagnose, and analyze various plan failures typical for performing everyday manipulation tasks.

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Camara, Ali, Alyssa George, Evan Hebner, Anika Mahmood, Jashun Paluru, and Seema Mattoo. "A Fluorescence Polarization-Based High-Throughput Screen to Identify the First Small-Molecule Modulators of the Human Adenylyltransferase HYPE/FICD." International Journal of Molecular Sciences 21, no. 19 (September 27, 2020): 7128. http://dx.doi.org/10.3390/ijms21197128.

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The covalent transfer of the AMP portion of ATP onto a target protein—termed adenylylation or AMPylation—by the human Fic protein HYPE/FICD has recently garnered attention as a key regulatory mechanism in endoplasmic reticulum homeostasis, neurodegeneration, and neurogenesis. As a central player in such critical cellular events, high-throughput screening (HTS) efforts targeting HYPE-mediated AMPylation warrant investigation. Herein, we present a dual HTS assay for the simultaneous identification of small-molecule activators and inhibitors of HYPE AMPylation. Employing the fluorescence polarization of an ATP analog fluorophore—Fl-ATP—we developed and optimized an efficient, robust assay that monitors HYPE autoAMPylation and is amenable to automated, high-throughput processing of diverse chemical libraries. Challenging our pilot screen with compounds from the LOPAC, Spectrum, MEGx, and NATx libraries yielded 0.3% and 1% hit rates for HYPE activators and inhibitors, respectively. Further, these hits were assessed for dose-dependency and validated via orthogonal biochemical AMPylation assays. We thus present a high-quality HTS assay suitable for tracking HYPE’s enzymatic activity, and the resultant first small-molecule manipulators of HYPE-promoted autoAMPylation.

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Dissanaike, Gishan, and Kim-Hwa Lim. "Detecting and Quantifying Insider Trading and Stock Manipulation in Asian Markets." Asian Economic Papers 14, no. 3 (October 2015): 1–20. http://dx.doi.org/10.1162/asep_a_00368.

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This paper focuses on insider trading, where the perpetrators exploit market sensitive information to earn profits or avoid losses. The paper's objectives are as follows. First, we seek to examine whether we can detect possible insider trading and stock manipulation and react in almost real time, even though insider trading activity is intended to be evasive. Second, we also estimate the extent of illicit profits (or loss avoidance) that might have been earned. Finally, we analyze, if detection is possible, the appropriate response for regulators and other market participants. We do not restrict our study to cases where corporate events have materialized, as we hope to capture insider trading surrounding market rumors and failed corporate events. Because insider trading is executed with the aim of being evasive and undetected, it is impossible to conclude with certainty. Nevertheless, using a hypothesized model based on how insiders and stock manipulators trade, we detect price patterns that are consistent with their objective to maximize profits and at the same time be evasive.

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Li, Haoxuan, Daoxiong Gong, and Jianjun Yu. "An obstacles avoidance method for serial manipulator based on reinforcement learning and Artificial Potential Field." International Journal of Intelligent Robotics and Applications 5, no. 2 (April 17, 2021): 186–202. http://dx.doi.org/10.1007/s41315-021-00172-5.

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AbstractThe obstacles avoidance of manipulator is a hot issue in the field of robot control. Artificial Potential Field Method (APFM) is a widely used obstacles avoidance path planning method, which has prominent advantages. However, APFM also has some shortcomings, which include the inefficiency of avoiding obstacles close to target or dynamic obstacles. In view of the shortcomings of APFM, Reinforcement Learning (RL) only needs an automatic learning model to continuously improve itself in the specified environment, which makes it capable of optimizing APFM theoretically. In this paper, we introduce an approach hybridizing RL and APFM to solve those problems. We define the concepts of Distance reinforcement factors (DRF) and Force reinforcement factors (FRF) to make RL and APFM integrated more effectively. We disassemble the reward function of RL into two parts through DRF and FRF, and make them activate in different situations to optimize APFM. Our method can obtain better obstacles avoidance performance through finding the optimal strategy by RL, and the effectiveness of the proposed algorithm is verified by multiple sets of simulation experiments, comparative experiments and physical experiments in different types of obstacles. Our approach is superior to traditional APFM and the other improved APFM method in avoiding collisions and approaching obstacles avoidance. At the same time, physical experiments verify the practicality of the proposed algorithm.

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Garza, H. H., O. Prakash, and D. J. Carr. "Aberrant regulation of cytokines in HIV-1 TAT72-transgenic mice." Journal of Immunology 156, no. 10 (May 15, 1996): 3631–37. http://dx.doi.org/10.4049/jimmunol.156.10.3631.

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Abstract The trans-activator of transcription or TAT gene from HIV-1 encodes a protein that increases the processivity of transcription from the HIV-1 genome. TAT protein can also affect cellular processes in the absence of its ribonucleic HIV target sequence trans activation response element and may be responsible for some aspects of HIV pathogenesis apart from infectious virus or other viral gene products. We have previously shown that TAT72 decreases CTL activity in TAT72-transgenic mice, and we now demonstrate aberrant regulation of mitogen-elicited IL-2 at both transcriptional and translational levels. In contrast, alloantigen stimulation resulted in increased IL-6 and IL-10 production in the TAT72-transgenic mice. Con A-stimulated cultures of splenic lymphocytes from TAT72-transgenic mice do not undergo clonal proliferation of CD4+ cells as compared with CD8+ cells monitored over 72 h. These results suggest that TAT is sufficient to induce some pathology associated with AIDS and is a potent immunologic manipulator apart from its function as trans-activator.

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Indri, Marina, Luca Lachello, Ivan Lazzero, Fiorella Sibona, and Stefano Trapani. "Smart Sensors Applications for a New Paradigm of a Production Line." Sensors 19, no. 3 (February 5, 2019): 650. http://dx.doi.org/10.3390/s19030650.

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Industrial plants are going to face a deep renewing process within the Industry 4.0 scenario. New paradigms of production lines are foreseen in the very near future, characterized by a strict collaboration between humans and robots and by a high degree of flexibility. Such envisaged improvements will require the smart use of proper sensors at very different levels. This paper investigates three different aspects of this industrial renewing process, based on three different ways of exploiting sensors, toward a new paradigm of a production line. The provided contributions, offering various types of innovation and integration, are relative to: (i) a virtual sensor approach for manual guidance, increasing the potentialities of a standard industrial manipulator, (ii) a smart manufacturing solution to assist the operator’s activity in manual assembly stations, through an original exploitation of multiple sensors, and (iii) the development of an advanced robotic architecture for a flexible production line, in which a team of autonomous mobile robots acts as a meta-sensor net supporting traditional automated guided vehicles. Accurate analyses of existing state-of-the-art solutions compared with the proposed ones are offered for the considered issues.

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Kostavelis, Ioannis, Andreas Kargakos, Evangelos Skartados, Georgia Peleka, Dimitrios Giakoumis, Iason Sarantopoulos, Ioannis Agriomallos, et al. "Robotic Assistance in Medication Intake: A Complete Pipeline." Applied Sciences 12, no. 3 (January 27, 2022): 1379. http://dx.doi.org/10.3390/app12031379.

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During the last few decades, great research endeavors have been applied to healthcare robots, aiming to develop companions that extend the independent living of elderly people. To deploy such robots into the market, it is expected that certain applications should be addressed with repeatability and robustness. Such application is the assistance with medication-related activity, a common need for the majority of elderly people, referred from here on as medication adherence. This paper presents a novel and complete pipeline for assistance provision in monitoring and serving of medication, using a mobile manipulator embedded with action, perception and cognition skills. The challenges tackled in this work comprise, among others, that the robot locates the medication box placed in challenging spots by applying vision based strategies, thus enabling robust grasping. The grasping is performed with strategies that allow environmental contact, accommodated by the manipulator’s admittance controller which offers compliance behavior during interaction with the environment. Robot navigation is applied for the medication delivery, which, combined with active vision methods, enables the automatic selection of parking positions, allowing efficient interaction and monitoring of medication intake activity. The robot skills are orchestrated by a partially observable Markov decision process mechanism which is coupled with a task planner. This enables assistance scenario guidance and offers repeatability as well as gentle degradation of the system upon a failure, thus avoiding uncomfortable situations during human–robot interaction. Experiments have been conducted on the full pipeline, including robot’s deployment in 12 real house environments with real participants that led to very promising results with valuable findings for similar future applications.

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Kovarikova, Zuzana, Frantisek Duchon, Andrej Babinec, and Dusan Labat. "Digital tools as part of a robotic system for adaptive manipulation and welding of objects." ACTA IMEKO 11, no. 3 (August 19, 2022): 1. http://dx.doi.org/10.21014/acta_imeko.v11i3.1271.

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Abstract:

<span>The aim of this article is to describe the design and verification of digital tools usable for sharing information within a team of workers and machines that manage and execute production carried out by a robotic system. The basic method is to define the structure of the digital tool and data flows necessary to enable an exchange of data needed to perform robotic manipulation and robotic welding of variable products minimizing at the same time strenuous human activity. The proposed structure of data interconnects a set of intelligent sensors with control of 18 degrees of freedom of 3 robotic manipulators, a welding device, and a production information system. Part of the work was also to verify the functionality of the proposed structure of the digital tools. In the first phase, simulations using a digital twin prototype of the workplace for robotic manipulation and robotic welding were performed to verify the functionality the digital tools. Subsequently, a digital tool was tested in the environment of a real prototype workplace for robotic manipulation and robotic welding. Simulation results and data obtained from the prototype tests proved the functionality of the digital tool inclusive of the production information system.</span>

Journal articles on the topic 'Activité manipulatoire'

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