Dissertations / Theses on the topic 'Action member'
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Coyer, Fiona Maree. "The Development of Family-Focused Intensive Care Nursing Through Action Research." Queensland University of Technology, 2004. http://eprints.qut.edu.au/15932/.
Full textvan, Duijn Diandra. "The Importance of Gender Equality in Climate Action : An investigation into how UN member states view the relation between gender equality and climate action." Thesis, Uppsala universitet, Institutionen för geovetenskaper, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-432709.
Full textBuchanan, Lauren-Ashley. "The dilemmatic nature of luring communication: an action-implicative discourse analysis of online predator and P-J member interaction." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/3054.
Full textRivera, Ricardo Enrique. "Studies into the mechanistic basis for local anesthetic action on transient receptor potential cation channel subfamily V member 1 in vitro." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44221.
Full textAndersson, Alexandra. "Youth Policy of the European Union : Implementation of the EU Youth Strategy for the action to reduce early school leavers within two member states." Thesis, Högskolan Dalarna, Statsvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:du-30971.
Full textPhillipo, Jean. "Obstacles to the Implementation of the Financial Action Task Force’s Recommendations in the Eastern and Southern African Anti-Money Laundering Group (ESAAMLG)." University of the Western Cape, 2011. http://hdl.handle.net/11394/5086.
Full textMoney laundering is a global problem that has adverse effects on both the developed and developing countries. If unchecked, it accelerates crime and criminal activities, affects the economy, undermines the integrity of financial markets, undermines the legitimate private sector, causes loss of revenue, poses security threats to privatisation efforts and brings about reputational risks as well as social costs.1 Given the transnational and cross-border nature of money laundering, the fight against it is global. This is why in 1989 the G72 countries decided to set up the FATF3 as a global standard-setting body for Anti-Money Laundering (AML) and combating of terrorist financing (CFT). The FATF has since developed standards for countries across the globe to adopt so as to facilitate this global fight. The standards are in the form of recommendations, and so far there are Forty Recommendations on money laundering (hereafter referred so as the Recommendations), Eight Special Recommendations on CFT, and a Ninth Special Recommendation on cash-couriers. In order to enhance its work and the adoption of its Recommendations, the FATF has also facilitated the establishment of FATF- styled regional bodies (hereinafter referred to as FSRBs) across the world. One such group is ESAAMLG, which was established in 1999. Its mandate is to coordinate and guide its member countries in the implementation of the Recommendations and guidelines. Currently, it has 15 member countries.8 Over the first ten years of its existence, among other things, ESAAMLG has through its members, achieved the following in its mandate: all members except Uganda have enacted AML legislation and some have set up structures that are essential for the implementation of the Recommendations Despite the above-mentioned achievements, the overall implementation of the Recommendations has been generally slow and low. Most of the member countries have not yet enforced their enacted AML legislation as evidenced by low rate of money laundering prosecutions in the region. Some have not yet established financial intelligence Units (FIUs) nor ratified or domesticated important AML related international legal instruments, let alone train personnel adequately. The international instruments comprise the 2000 United Nations Convention against Transnational Organised Crime (Palermo Convention) and the1988 United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances (Vienna Convention). There are also inordinate delays in the passing of AML legislation as well as the amendment of other domestic legislation, which is necessary in order to harmonise such laws with the AML standards. This gives rise to unevenness, disconnectedness and time variability in the implementation of the Recommendations among the member countries. The main question this paper seeks to answer is this: Are there obstacles to the implementation of the Recommendations in Eastern and Southern Africa?
Holliday, Christopher Scott. "Understanding Member Engagement through Participation and Commitment in a Community-Based Health Coalition, 1994-2008: A Mixed-Methodological Study." unrestricted, 2008. http://etd.gsu.edu/theses/available/etd-07182008-165543/.
Full textTitle from file title page. James Emshoff, committee chair; Bethann Cottrell, Marci Culley, John Peterson, Sarah Cook, committee members. Electronic text (202 p. : ill. (some col.)) : digital, PDF file. Description based on contents viewed Nov. 19, 2008. Includes bibliographical references (p. 153-165).
Sow, Idrissa. "La protection de l’ordre juridique sous-régional par les Cours de justice : contribution à l’étude de la fonction judiciaire dans les organisations ouest-africaines d’intégration." Thesis, Bordeaux 4, 2013. http://www.theses.fr/2013BOR40029.
Full textAfter being freed from colonization, the West African States have set up commonly economic integration organizations to promote their economic and social development.The creation of the majority of those organizations is based on the European example and they have an independent legal personality and a body with specific rules in charge of integrating uniformly the internal legal environment of the different Member States.The harmonious functioning of the system requires, among others, the existence of an independent structure designed to take control of the general balance organization and achieve a uniform interpretation of the Community norms. Within the framework of the WAEMU as well as in the ECOWAS, this protective function is delegated to integrated judicial bodies whose main mission consists in making sure that a submission to the law related to the interpretation and compliance with Treaties is effective.The goal of such a contribution is to point out that the settled protection device is functioning, on the one hand, by the cooperation mechanisms introduced by justice courts and the other components of the Community system and, on the other hand, by the judicial control over the community structures and the Member States
Middlebro, Allen. "Choices and actions of members and former members of the French Communist Party, 1939-1941." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.543640.
Full textJulian, Dianna L. "Turnover at Lockheed Martin a study in how to retain team members /." [Denver, Colo.] : Regis University, 2006. http://165.236.235.140/lib/DJulian2006.pdf.
Full textXefteri, Stamatina. "Les directives européennes, instrument juridique des autorités administratives nationales." Thesis, Paris 2, 2019. http://www.theses.fr/2019PA020022.
Full textEuropean Union directives have always been considered as a legal instrument relied upon by individuals vis-à-vis a defaulting Member State. The right to rely on directives as well as their application are examined under the sole lens of the rights of the litigants. Contrary to this perspective, the present study aims to demonstrate that directives become a legal means of intervention in the domestic legal order, insofar as national authorities rely on and apply them in their relations with citizens and other national or European authorities. The emergence of secondary legislation has disrupted the hierarchy of norms, as well as reshaped the obligations imposed on the administrative authorities. On the basis of the primacy of European Union law and the imperative of efficiency in all Member States, the legality of national rules requires compliance with directives. Thus, directives claim their place among the conventional parameters of legality, but they also come in conflict with the latter at times or even replace any national rule to the contrary effect. However, the directive as an instrument is not only a source of supranational law in the hands of the administration to be applied passively, but also a European standard used to serve its own purposes, as well as the objectives pursued by the European Union. In fact, the evolution of European and administrative case-law has not only led to a strengthening of the obligations of the administration, but has also amplified the forms of relying on a directive to the benefit of the administration and recognized the autonomy of the administrative authorities over the legislature as far as the implementation of directives is concerned. These elements reveal the particularly dynamic role of all the administrative authorities acting within the scope of the directives, in their transposition and implementation in the national legal orders
Albertse, Lizelle. "Gang members' experiences of victimization and perpetration of rape in prison." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_7518_1241763499.
Full textPeople outside of prison tend to imagine sex in prison as violent gang attacks on defenceless individuals, but in actual fact, sex in prison is more complicated than the isolated gang rapes that take place. For the purpose of this study, the researcher followed the qualitative research approach from a constructivist perspective to understand how participants portrayed or constructed their experiences of victimization and/or perceprion of rape.
Taute, Wiehahn. "The experiences of affirmative action of a private hospital's staff members / Wiehahn Taute." Thesis, North-West University, 2004. http://hdl.handle.net/10394/296.
Full textThesis (M.A. (Industrial Psychology))--North-West University, Potchefstroom Campus, 2004.
Katz, Joel. "A study of affirmative action policies practised by members of the East Cape Master Builders and Allied Industries Association." Thesis, Port Elizabeth Technikon, 2001. http://hdl.handle.net/10948/d1011326.
Full textDelecourt, Benoist. "Les contrats civils appliqués aux actions." Phd thesis, Université du Droit et de la Santé - Lille II, 2010. http://tel.archives-ouvertes.fr/tel-00577724.
Full textNuhu, Assuman. "Factors influencing implementation of soccer injury prevention strategies in Rwanda." Thesis, University of the Western Cape, 2008. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_4867_1271621548.
Full textBackground: Three epidemiological studies conducted in Rwanda have highlighted that many people at different levels in the community of soccer do not implement accepted control measures for reducing the risk of injuries. However, little is known about what soccer community members themselves know about injury prevention. Purpose: The aim of this study was to identify perceptions of factors influencing the implementation of soccer injury prevention strategies in Rwanda.
Bartley, Tracey Mac. "Teaching new members how to become ministers at Acton Baptist Church." Theological Research Exchange Network (TREN) Access this title online, 2006. http://dx.doi.org/10.2986/tren.049-0483.
Full textBartley, Tracey M. "Teaching new members how to become ministers at Acton Baptist Church." Theological Research Exchange Network (TREN), 2006. http://www.tren.com/search.cfm?p049-0483.
Full textAbels, Charlene E. "Perceptions of service delivery by the Philippi Trust to the HIV/AIDS support groups in the Helderberg Region." Thesis, University of the Western Cape, 2008. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_5070_1260356689.
Full textThis descriptive study investigated the utilisation of and perceptions about service delivery by Philippi Trust in the HIV/AIDS support groups in the Helderberg region. A questionnaire and individual interviews were applied to gather the data from the HIV/AIDS support group members and their facilitators. The quantitative data analysis was done, using the Statistical Packaging for Social science (SPSS) aiming to determine the descriptive statistics of the database and variables. The qualitative analysis was conducted using thematic analysis. Anonymity was assured but complete confidentiality was not possible as the investigator had knowledge of the HIV status of the study population, however no names appeared in the research report.
Milanezi, Maicon José de Faria. "“Elegemos um meme?!” : política e experiência estética nos memes de ação popular das Eleições 2018 /." Bauru, 2019. http://hdl.handle.net/11449/190835.
Full textResumo: Esta pesquisa busca analisar os memes políticos a partir da ótica da inserção das pessoas militantes em comportamentos coletivos e compartilhados de apoio ou oposição a candidaturas, tendo em vista o segundo turno das Eleições Presidenciais de 2018. Para tanto, constrói-se uma exploração teórica que leva em conta as transformações da sociedade em vias de midiatização, onde os processos de interação tecidos em redes são híbridos e as lógicas sociais, altamente baseadas no midiático, pois passam a levar em conta dinâmicas desse campo social sobretudo quando se observa as instituições e mobilizações políticas. O trabalho se baseia no pensamento político de Jacques Rancière (1996, 2009, 2012, 2016), para quem a política é a contestação da ordem policial que estabelece hierarquicamente lugares definidos a serem ocupados pelos indivíduos e uma partilha do sensível consensual, não se restringindo à estrutura jurídico-política de gestão dos interesses coletivos. São apresentados, então, partindo de Dawkins (2018 [1976]) e Shifman (2014), os desdobramentos investigativos que enquadram os memes como elementos dotados de sentidos que encontram nos sites de redes sociais um ambiente fecundo para se multiplicarem e serem capazes de conformar ação política. Com base, especificamente, nos memes de ação popular, caracterizados por ações coletivas performáticas com teor comportamental apropriados por essas militâncias para pautar discussões, visa-se compreender se eles instituem o que Braga (... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: This research seeks to analyze the political memes from the perspective of the insertion of the militants into collective and shared behaviors of support or opposition to candidacies, in consideration of the second round of the 2018 Brazilian Presidential Election. For this, a theoretical exploration is constructed to take into account the transformations of the society in the process of mediatization, where the processes of interaction that woven into networks are hybrids and the social logics are highly based on the media since they adopt dynamics of this social field which is noted especially when observing the political institutions and mobilizations. This work is based on the political thinking of Jacques Rancière (1996, 2009, 2012, 2016), for whom politics is the contestation of the police order that establishes hierarchically defined places to be occupied by people and a consensual distribution of the sensible, not restricting itself to the juridical-political structure of management of the collective interests. Then, are presented, starting from Dawkins (2018 [1976]) and Shifman (2014), the investigative unfoldings that frame the memes as meaningful elements that find in social networking sites a fruitful environment to multiply and be able to conform political action. Based specifically on the memes grassroots action, characterized by collective performatic actions with behavioral content appropriated by these militants to guide discussions, it is sought to understan... (Complete abstract click electronic access below)
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Gross, Clare M. "Understanding the Attitudes and Beliefs of Faculty Members in Regards to Learning Communities at Cleveland State University." Cleveland State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=csu1259944870.
Full textIsaacs, Roshan. "Comparison of physical activity practices and dietary habits of health club members and community controls in Khayelitsha, Cape Town." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_4386_1256889698.
Full textChronic diseases pose public health concerns globally with an increasing trend in developing countries. The development of interventions to minimize or prevent the burden associated with chronic diseases has therefore become a necessity. In 2002 the School of Public Health of the University of the Western Cape developed a health club intervention in Khayelitsha. This intervention focused on promoting healthy lifestyles, particularly improved diet and physical activity. The objectives of this study was to determine whether members were more physically active than non-members and to determine whether members made healthier dietary choices than non-members.
Zagarese, Vivian. "Leadership During Action Team Formation: The Influence of Shared Leadership Among Team Members During the Perioperative Process." Thesis, Virginia Tech, 2020. http://hdl.handle.net/10919/100875.
Full textM.S.
In the field of Industrial and Organizational Psychology, many leadership theories have been developed, however, there is a lack of understanding as to which type of leadership is best for teams who work in high-stress environments, such as the operating room. This study looks at two types of leadership: shared leadership and autocratic leadership. Shared leadership is when all team members emerge and have a leadership role, whereas autocratic leadership is when one person makes all the decisions without consulting other team members. Previous research has articulated leadership behaviors, but has largely ignored the temporal processes of leadership, and how it changes over time throughout the surgical procedure. This study builds upon other studies by testing how leadership behaviors are related to levels of psychological safety and the optimization of teamwork and communication among team members. We were also interested in understanding if the surgeon’s perception of past performance of their team has an impact on the amount of trust the leader has in his/her team and if this in turn, has an impact on the type of leadership utilized during the team’s tenure. As an exemplar environment, we explored these dynamics in the operating theater, which is a high stakes environment requiring both technical and non-technical skills, such as leadership, communication, and teamwork. Results show that the relationship between the surgeon’s perceived past performance of the team and the trust the surgeon has in his/her team is significant and the relationship between the trust the surgical team members have in each other and the amount that they communicate with each other is also significant.
Attanasio, Kyle J. "The implications of elections on actions of senators and members of parliament in Canada." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/34977.
Full textKajura, Naaman N. "The perceived and experienced barriers and reported consequences of Hiv positive status disclosure by people living with Hiv to their partners and family members in Djibouti." Thesis, University of the Western Cape, 2010. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_1536_1299479970.
Full textThis was a descriptive qualitative study. Eight people living with HIV, four of which had disclosed their status, were individually interviewed. Two focus group discussions (each comprising 6 participants) were also conducted with health workers. The study was based at an urban TB hospital which is currently providing a range of HIV-related services including HIV Voluntary Counselling and Testing, case management and treatment.
Joorst, Jerome Paul. "The nature of the representative council of Learner (RCL) members' participation on the school governing bodies of two primary schools in the Western Cape." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_4757_1256304733.
Full textThis study is based on an investigation into the way RCL members participate in the deliberation of their School Governing Bodies. The study was conducted in two primary schools in the Western Cape town of Vredenburg. The research participants were members of the Representative Council of Learners from these schools. Focus group discussions as well as in depth interviews were used to explore the RCL members' views on the nature of their participation during SGB deliberations. the main fining of this study is that, due to external as well as in-school factors, a huge gap exists between normative RCL policy exp[ectations and the actual manifestation policy in the real world of the RCL members' schools. the findings of the study reveal a lack of participative capacities among these RCL members, which, in combination with a non participative culture at their homes, the community and the school, leads to learners being excluded from democratic processes.
Schonegg, Stephanie. "Rho GTPase family members in establishment of polarity in C. elegans embryos." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2006. http://nbn-resolving.de/urn:nbn:de:swb:14-1139490285625-55732.
Full textVerrett, Shannon L. "Gender Perceptions of Administrative Team Members Regarding Secondary Principals' Leadership Actions and Behaviors in Managing Change." ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1542.
Full textAppel-Silbaugh, Cara D. "Acting out integrity and honor student honor council cultural influence on members' development /." College Park, Md. : University of Maryland, 2007. http://hdl.handle.net/1903/7158.
Full textThesis research directed by: Counseling and Personnel Services. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
Guiraud, David. "Système de contrôle du mouvement du membre inférieur à base de réseaux de neurones artificiels : restauration de la marche chez le paraplégique." Châtenay-Malabry, Ecole centrale de Paris, 1993. http://www.theses.fr/1993ECAP0318.
Full textSchonegg, Stephanie. "Rho GTPase family members in establishment of polarity in C. elegans embryos." Doctoral thesis, Technische Universität Dresden, 2005. https://tud.qucosa.de/id/qucosa%3A24640.
Full textCook, Jeffrey L. "Equipping selected members of Bayou Plaquemine Baptist Church to develop a missions action strategy for the small church, Plaquemine, Louisiana." Theological Research Exchange Network (TREN), 1994. http://www.tren.com.
Full textBjörkman, Hans. "Learning from members : tools for strategic positioning and service innovation in trade unions." Doctoral thesis, Handelshögskolan i Stockholm, Programmet Människa och Organisation (PMO), 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:hhs:diva-530.
Full textDiss. Stockholm : Handelshögskolan, 2005
Liu, Tingting. "MATTERING PERCEPTIONS AND ACADEMIC SUCCESS OF MILITARY SERVICE MEMBERS IN HIGHER EDUCATION." OpenSIUC, 2020. https://opensiuc.lib.siu.edu/dissertations/1882.
Full textLee, Myong Jae. "Effects of attitude and destination image on association members' meeting participation intentions : development of meeting participation model." Diss., Manhattan, Kan. : Kansas State University, 2005. http://hdl.handle.net/2097/69.
Full textBaril, Mathieu. "Conception d'un préhenseur sous-actionné pour les prothèses de membre supérieur et analyse de stabilité." Thesis, Université Laval, 2012. http://www.theses.ulaval.ca/2012/28932/28932.pdf.
Full textLovell, Jacqueline Marie Grace. "So what's changed? : participatory action research through which diverse members co-evaluate their community organisation to creatively document their experiences and outcomes." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/18274/.
Full textHultén, Adam. "Family Ownership and Payout Policy : A Study of Ownership and Dividend Policies in Swedish Firms." Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-414594.
Full textGuay, François. "Analyse cinémato-statique d'un doigt sous-actionné à 3 DDL pour une prothèse de membre supérieur." Thesis, Université Laval, 2012. http://www.theses.ulaval.ca/2012/28618/28618.pdf.
Full textGuay, Martin F. "Analyse cinémato-statique d'un doigt sous-actionné à 3 DDL pour une prothèse de membre supérieur." Master's thesis, Université Laval, 2012. http://hdl.handle.net/20.500.11794/23224.
Full textForman, Todd. "Designing and presenting a ministry action plan based on the ministry needs assessment of selected members of the First Baptist Church of Versailles, Missouri." Theological Research Exchange Network (TREN) Access this title online, 2005. http://www.tren.com.
Full textTornero, Stephen A. "Motivating young adolescents in an inclusion classroom using digital and visual culture experiences: An action research." Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1429210198.
Full textBihina, Gisèle. "Analyse du comportement au feu des planchers mixtes acier-béton constitutés de poutres cellulaires." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2011. http://tel.archives-ouvertes.fr/tel-00673404.
Full textVALENTIM, DANIELA FRIDA DRELICH. "AFFIRMATIVE ACTION POLICIES AND HIGHER EDUCATION: THE EXPERIENCE OF THE STATE UNIVERSITY OF RIO DE JANEIRO (UERJ) IN THE PERSPECTIVE OF THE LAW SCHOOL FACULTY MEMBERS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2005. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=7712@1.
Full textTrata o presente estudo da adoção de ações afirmativas no ensino superior público no Brasil, especificamente, na Universidade do Estado do Rio de Janeiro. O objetivo geral da pesquisa foi analisar a experiência das ações afirmativas, modalidade cotas, implementadas no ano de 2003, pela UERJ, sua gênese, características, implantação e primeiros resultados. Pretendeu ainda, conhecer essa experiência mais especificamente, num espaço considerado de especial prestígio acadêmico na universidade: a Faculdade de Direito, tendo como recorte a posição de seus professores acerca daquela experiência já implementada em suas salas de aula. Optamos por uma abordagem do tipo qualitativa. Foi realizada uma pesquisa bibliográfica sobre a temática das ações afirmativas, um levantamento dos documentos e estatísticas oficiais da universidade e entrevistas semi-estruturadas com os professores da referida Faculdade. A experiência de 2003 demonstrou a viabilidade política e acadêmica de um acesso mais democrático aos cursos considerados de maior status social, entretanto, a questão da permanência dos alunos cotistas num quadro de insuficiência de recursos da universidade tem gerado tensões e desafios que cabem à comunidade interna da UERJ e também a externa enfrentar.
The current study focuses on the adoption of affirmative action policies by the public sector higher education system in Brazil, more specifically by the State University of Rio de Janeiro (UERJ). The overall purpose of the research was to analyse the UERJ experience of introducing affirmative action in 2003 by means of a quota system, taking into consideration its genesis, characteristics, implementation and initial results. The study aimed in particular at investigating the experience within the boundaries of a highly prestigious academic space in this University - the Law School - focusing on the stance adopted by the faculty with regard tothe experience already being implemented in their classrooms. We have opted for a qualitative approach in our research. To this end, a review of the literature on the topic of affirmative action, a survey of University official documents and statistical data as well as semi-structured interviews with Law School faculty members were carried out. The 2003 experience proved the political and academic viability of a more democratic access to courses of higher social status. However, the issue of the permanence of quota students in a context where University resources are insufficient has generated tensions and challenges that both the UERJ and the wider communities will inevitably have to meet.
Moffet, Suzanne. "Le vécu des femmes membres du personnel de secrétariat au fil des âges." Master's thesis, Université Laval, 1987. http://hdl.handle.net/20.500.11794/29228.
Full textOlofsson, Simon. "$GME To The Moon : Mapping Memetic Discourse as Discursive Strategyin Reddit Trading Community r/WallStreetBets during the GameStop Short Squeeze Saga." Thesis, Stockholms universitet, JMK, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-196319.
Full textFranzén, Åsa. "Regulatory Effects of TGF-β Superfamily Members on Normal and Neoplastic Thyroid Epithelial Cells." Doctoral thesis, Uppsala University, Department of Genetics and Pathology, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1624.
Full textThyroid growth and function is partly regulated by growth factors binding to receptors on the cell surface. In the present thesis, the transforming growth factor-β (TGF-β) superfamily members have been studied for their role in regulation of growth and differentiation of both normal and neoplastic thyroid epithelial cells.
TGF-β1 is a negative regulator of thyrocyte growth and function. However, the importance of other TGF-β superfamily members has not been fully investigated. TGF-β1, activin A, bone morphogenetic protein (BMP)-7 and their receptors were found to be expressed in porcine thyrocytes. In addition to TGF-β1, activin A was also found to be a negative regulator of thyroid growth and function, and both stimulated phosphorylation and nuclear translocation of Smad proteins. Furthermore, TGF-β1 and epidermal growth factor (EGF) demonstrated a synergistic negative effect on thyrocyte differentiation. Simultaneous addition of the two factors resulted in a loss of the transepithelial resistance and expression of the epithelial marker E-cadherin. This was followed by a transient expression of N-cadherin.
Despite the extremely malignant character of anaplastic thyroid carcinoma (ATC) tumor cells, established cell lines are still responsive to TGF-β1. A majority of the cell lines were also found to be growth inhibited by BMP-7. BMP-7 induced cell cycle arrest of the ATC cell line HTh 74 in a dose- and cell density-dependent manner. This was associated with upregulation of p21CIP1 and p27KIP1, decreased cyclin-dependent kinase (Cdk) activity and hypophosphorylation of the retinoblastoma protein (pRb). TGF-β1, and to some extent also BMP-7, induced the expression of N-cadherin and matrix metalloproteinase (MMP)-2 and -9. Stimulation of HTh 74 cells with TGF-β1 increased the migration through a reconstituted basement membrane indicating an increased invasive phenotype of the cells.
Taken together, these data show that TGF-β superfamily members not only affect growth and function of normal thyroid follicle cells but may also, in combination with EGF, play a role in cell dedifferentiation. This study additionally suggests that the TGF-β superfamily members may be important for the invasive properties of ATC cells.
Huo, Weiguang. "Stratégies de commandes assistives pour les exosquelettes des membres inférieurs." Thesis, Paris Est, 2016. http://www.theses.fr/2016PESC1041/document.
Full textNeurological problems caused by stroke and spinal cord injury as well as the weakness of skeletal muscles may considerably affect the motor ability of the elderly and infirm. Traditional solutions of assistance and treatment for these dependent people are relatively costly; they generally need significant human efforts and financial resources from caregivers and national healthcare centers. In this context, robotics appears as a convenient and promising solution to develop assistive systems for improving the autonomy of dependent people. Lower limb exoskeletons are wearable robots that can be used as assistive devices for augmenting the wearer’s motor ability and/or improving the effectiveness of neuromuscular rehabilitation. Recently, they have attracted increasing interest in the robotics community. As lower limb exoskeletons exhibit close cognitive and physical interactions with the wearer, a fundamental function is to provide appropriate power assistance by taking into account the wearer’s sensor-motor ability. Consequently, it is of great importance to develop human intention based control strategies. Meanwhile, from the exoskeleton’s viewpoint, the physical contacts with the wearer and the environment are both considered disturbances affecting the accomplishment of the wearer’s desired movements. These disturbances should also be taken into account during the design of control strategies.In this thesis, we develop three assistive control strategies for lower limb exoskeletons. In the meantime, two modes of assistance are studied: the passive mode in which the wearer has very limited motor ability as well as the active-assisted mode in which the wearer has certain motor ability but that is insufficient to perform autonomously a desired physical movement. In the first control strategy, the wearer is assumed to be in passive mode. A robust sliding mode control approach is developed based on the use of a nonlinear disturbance observer, in order to guarantee accurate tracking performance of desired knee joint movements. In the second control strategy, we propose a human intention based nonlinear active impedance control structure, in which the wearer is in an active-assisted mode. This assistive strategy is used to assist the wearer in single-task physical activities, for instance, the knee joint flexion/ extension movement. We investigate the performance of the proposed control structure based on two case studies: knee-joint flexion/extension movements and sit-to-stand movements. Finally, the third control strategy is developed to assist the wearer during walking activities. We propose a new approach that is able to detect the gait mode at the early beginning of a new step using the kinematic features namely velocity and position of the wearer’s feet during walking. The proposed gait mode detection approach makes it possible to select appropriate kinematic and kinetic models for each gait mode. Different assistive strategies are developed: partial gravity compensation, virtual-spring/damper based impedance assistance and zero impedance assistance. These strategies are combined differently according to the estimated wearer’s gait mode. To evaluate the proposed control strategies, two lower limb exoskeleton prototypes are developed: a knee joint lower limb exoskeleton, called EICOSI, and a full lower limb exoskeleton, called E-ROWA
Jackson, Louise. "Discover Knowledge, Attitudes, Actions About Ministering to the Mentally Ill inthe Cleveland District." Ashland Theological Seminary / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=atssem1588278720539611.
Full textClinton, John E. (John Eric). "An Investigation of the Self-perceptions Certified Fine Arts Teachers Have Toward Their Roles as Artist and Instructional Staff Member in Selected Public High Schools of Oklahoma." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc277787/.
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