Academic literature on the topic 'Actin regulators'
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Journal articles on the topic "Actin regulators":
Ma, Xuda, Yamei Dang, Xiaowen Shao, Xuechun Chen, Fei Wu, and Yongmei Li. "Ubiquitination and Long Non-coding RNAs Regulate Actin Cytoskeleton Regulators in Cancer Progression." International Journal of Molecular Sciences 20, no. 12 (June 19, 2019): 2997. http://dx.doi.org/10.3390/ijms20122997.
Siripala, Anosha D., and Matthew D. Welch. "SnapShot: Actin Regulators I." Cell 128, no. 3 (February 2007): 626.e1–626.e2. http://dx.doi.org/10.1016/j.cell.2007.02.001.
Siripala, Anosha D., and Matthew D. Welch. "SnapShot: Actin Regulators II." Cell 128, no. 5 (March 2007): 1014.e1–1014.e2. http://dx.doi.org/10.1016/j.cell.2007.02.021.
Ferrai, Carmelo, Gabriela Naum-Onganía, Elena Longobardi, Martina Palazzolo, Andrea Disanza, Victor M. Diaz, Massimo P. Crippa, Giorgio Scita, and Francesco Blasi. "Induction of HoxB Transcription by Retinoic Acid Requires Actin Polymerization." Molecular Biology of the Cell 20, no. 15 (August 2009): 3543–51. http://dx.doi.org/10.1091/mbc.e09-02-0114.
Rohn, Jennifer L., David Sims, Tao Liu, Marina Fedorova, Frieder Schöck, Joseph Dopie, Maria K. Vartiainen, Amy A. Kiger, Norbert Perrimon, and Buzz Baum. "Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype." Journal of Cell Biology 194, no. 5 (September 5, 2011): 789–805. http://dx.doi.org/10.1083/jcb.201103168.
Martin, Jose L., Aaqil Khan, and Elena E. Grintsevich. "Actin Isoform Composition and Binding Factors Fine-Tune Regulatory Impact of Mical Enzymes." International Journal of Molecular Sciences 24, no. 23 (November 23, 2023): 16651. http://dx.doi.org/10.3390/ijms242316651.
Burston, Helen E., Lymarie Maldonado-Báez, Michael Davey, Benjamen Montpetit, Cayetana Schluter, Beverly Wendland, and Elizabeth Conibear. "Regulators of yeast endocytosis identified by systematic quantitative analysis." Journal of Cell Biology 185, no. 6 (June 8, 2009): 1097–110. http://dx.doi.org/10.1083/jcb.200811116.
Steinestel, Konrad, Eva Wardelmann, Wolfgang Hartmann, and Inga Grünewald. "Regulators of Actin Dynamics in Gastrointestinal Tract Tumors." Gastroenterology Research and Practice 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/930157.
Ono, Kanako, and Shoichiro Ono. "Tropomyosin and Troponin Are Required for Ovarian Contraction in the Caenorhabditis elegans Reproductive System." Molecular Biology of the Cell 15, no. 6 (June 2004): 2782–93. http://dx.doi.org/10.1091/mbc.e04-03-0179.
Zhang, Huaye, Donna J. Webb, Hannelore Asmussen, and Alan F. Horwitz. "Synapse formation is regulated by the signaling adaptor GIT1." Journal of Cell Biology 161, no. 1 (April 14, 2003): 131–42. http://dx.doi.org/10.1083/jcb.200211002.
Dissertations / Theses on the topic "Actin regulators":
Metelo, J. "Contribution of integrins and actin regulators to human dendritic cell podosome biology." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1381835/.
McShea, Molly A. "Evidence of an interaction between the actin cytoskeletal regulators MIG-10 and ABI-1." Digital WPI, 2011. https://digitalcommons.wpi.edu/etd-theses/983.
Baskaran, Darshan. "Investigating the role of a dynamic actin cytoskeleton and its regulators for HIV-1 entry in macrophages." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:497e66e0-4b67-4e0e-9616-07628e493293.
Jones, Rebecca Amy. "Testing the in vivo role of actin cytoskeleton regulators on immune cell behaviour by live imaging studies in Zebrafish larvae." Thesis, University of Bristol, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617798.
Cercy, Maureen. "Organisation à l'échelle nanométrique du complexe régulateur de WAVE dans le lamellipode de cellule en migration." Electronic Thesis or Diss., Bordeaux, 2023. http://www.theses.fr/2023BORD0461.
Cell motility is involved in critical biological functions, and dysregulation of adhesion, migration and of the actin cytoskeletal can lead to severe disease like cancer. Therefore, it is essential to study the molecular mechanism driving the formation of sub-cellular structures involved in cell motility. The first step in mesenchymal cell migration is the forward protrusion of the lamellipodium which is a thin sheet of membrane-enclosed actin filaments (F-Actin) networks propelled by actin polymerization. The spatiotemporal coordination of F-actin regulators in the lamellipodium determines the polarity, architecture and movements of branched F-actin networks. This includes two interacting nanomachines, the WAVE regulatory complex (WRC) and the Arp2/3 complex. WRC activation is the central molecular event triggering Arp2/3 complex activation and thus, the initiation and formation of a branched F-actin network in the lamellipodium. WRC activation relies on the exposure of the cryptic Arp2/3-activating WCA domain located at the C-terminal extremity of the WAVE subunit tail. In vitro studies showed that two WCA domains are needed to efficiently activate the Arp2/3 complex.But how the local spatial organization of WRC at the molecular level translate into activation of the Arp2/3 complex triggering the morphogenesis of the lamellipodium is unknown. In other words, the stoichiometry and the spatial distribution required to translate WRC conformational activation to an efficient activation of Arp2/3 complex are essential missing information.The recent application of super-resolution microscopy (SRM) and single particle tracking (SRM) lead to a drastic rethinking of macromolecular assemblies, in particular structures involved in cell migration, including the lamellipodium. By tracking individual proteins and delivering images with spatial resolutions below the diffraction limit of light, these techniques give access to the nanoscale organization and dynamics of protein complexes in live cells.To reveal the molecular organization of WRC, we use DNA-PAINT, a SRM technique which allows spatial resolution below 10 nm. DNA-PAINT is based on hybridization of complementary DNA strands, one located on the target protein (docking strand) and the other on the dye (imager strand). DNA-PAINT enable absolute molecular counting in protein complexes (Quantitative-PAINT) and multi-color super-resolution imaging (Exchange-PAINT). This allowed us to assess stoichiometries, colocalizations and composition of nanomachines in the lamellipodium.Using Quantitative-PAINT, we showed that the stoichiometry of WRC at the lamellipodium tip of migrating mouse melanoma cell (B16) is one; while live super-resolution imaging based on RESOLFT nanoscopy revealed that these single WRC form discrete foci at the lamellipodium tip. Multicolor Exchange-PAINT super-resolution microscopy of the WRC core and its WCA domain, showed that its conformational activation induces the release of the WCA domain in a radius of 40 nm away from its core. Using stereotyped waveform protrusions, we correlated WRC molecular organization with the rate of membrane protrusions. We showed that the spatial distribution of individual WRC is below the radius of its conformational unfolding in regions of faster lamellipodial protrusion, increasing the possibility of WCA domain dimerization and thus activation of the Arp2/3 complex. This way, the WRC, functioning as an isolated complex, must be spaced at a distance less than its conformational unfolding to activate efficiently the Arp2/3 complex in the lamellipodium. Altogether, our results show that besides biochemical activation of signaling circuitry, the spatial organization of proteins is crucial for controlling their function in cells
Akbari, Omar Sultan. "Novel gene regulatory mechanisms in Drosophila melanogaster." abstract, 2008. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3339089.
Graham, Alison Isobel. "Action and metal-specificity of SmtB/ArsR transcriptional regulators." Thesis, University of Newcastle Upon Tyne, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427312.
Temple-Smith, Kay Elizabeth. "The mode of action of novel plant growth regulators." Thesis, University of Bristol, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317880.
Dufort, Paul Anthony. "Computational modeling of nucleotide processing by the actin cytoskeleton regulatory network." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0022/NQ49953.pdf.
Liu, Chaohong. "Regulatory functions of the actin cytoskeleton in B cell receptor signaling." Thesis, University of Maryland, College Park, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3599621.
The binding of antigen (Ag) to the B cell receptor (BCR) induces the activation of intracellular signaling and the reorganization of the actin cytoskeleton. However, the function of actin reorganization and the mechanisms by which BCR signaling and actin reorganization is coupled have not been well studied. This thesis has investigated how BCR signaling regulates actin reorganization and how actin remodeling in turn influences BCR signalig. My studies show that the key stimulatory signaling molecule of the BCR, Bruton's tyrosine kinase (Btk), is critical for actin polymerization at the activation surface and BCR clustering and B cell spreading, events that are essential for signaling initiation and amplification. The key inhibitory signaling molecule, SH2-containing phosphatidylinositol-5 phasphatase (SHIP-1), is important for removal of F-actin from the activation surface, and actin-mediated B cell contraction and the formation of BCR central clusters. SHIP-1 suppresses actin polymerization by inhibiting Btk-dependent activation of Wiskott-Aldrich syndrome protein (WASP). These results suggest that BCR signaling can regulate B cell morphology and surface BCR clustering via modulationg actin dynamics. To understand the roles of actin reorganization in BCR signaling, I investigated the effects of gene knockout of the two actin regulators, WASP and its homolog, neuronal (N)-WASP. My results show that both WASP and N-WASP are required for optimal BCR clustering, B cell spreading, and BCR signaling, but they play distinct roles. WASP promotes actin polymerization, B cell spreading, BCR clustering, and signaling amplification, and N-WASP inhibits actin polymerization at the activation surface and promotes B cell contraction, BCR central cluster formation, and signaling attenuation. Importantly, B cell-specific N-WASP knockout causes increases in the levels of autoantibody. In addition, WASP and N-WASP negatively regulate each other, compete for Arp2/3, and are inversely regulated by Btk and SHIP-1. Taken together, these results demonstrate that the balance of stimulatory and inhibitory BCR signaling controls actin dynamics and organization through regulating the activities of WASP and N-WASP. Actin remodeling in turn amplifies BCR signaling activation or down regulation by modulating B cell morphlogy and the organization of surface BCRs.This research reveals a bidrectional feedback loop between BCR signaling and the actin cytoskeleton.
Books on the topic "Actin regulators":
Education, Alberta Alberta. Regulatory reform action plan. [Edmonton]: Communications Branch, Alberta Education, 1996.
Education, Alberta Alberta. Regulatory reform: Action plan. Edmonton, AB: Alberta Education, 1996.
U.S. Nuclear Regulatory Commission. Advisory Committee on Nuclear Waste. ACNW 2001 action pl. [Washington, D.C.?]: U.S. Nuclear Regulatory Commission, 2001.
Office, Nebraska Affirmative Action. Affirmative Action Program rules & regulations. [Lincoln]: Affirmative Action Office, Nebraska Dept. of Personnel, 1988.
Safeguards, U. S. Nuclear Regulatory Commission Advisory Committee on Reactor. 2001 action plan. [Washington, D.C.]: U.S. Nuclear Regulatory Commission, 2001.
Evanoff, Douglas Darrell. Subordinated debt and prompt corrective regulatory action. [Chicago, Ill.]: Federal Reserve Bank of Chicago, 2003.
Copping, Leonard G. Chemistry and mode of action of crop protection agents. Cambridge, UK: Royal Society of Chemistry, Information Services, 1998.
Petty, Janette E. Wood preservatives: A chronology of regulatory action & bibliography. Washington, D.C: Office of Pesticides and Toxic Substances, Office of Toxic Substances, Information Management Division, Chemical Information Branch, 1985.
Toy, Safety Conference (1989 Washington D. C. ). Toy safety: Blueprint for action. Washington, DC (1050 31st St., NW, Washington 20007): Association of Trial Lawyers of America, 1991.
Bureau of National Affairs (Washington, D.C.), ed. Affirmative action after Adarand: A legal, regulatory, legislative outlook. Washington, D.C: The Bureau of National Affairs, 1995.
Book chapters on the topic "Actin regulators":
Paul-Gilloteaux, Perrine, François Waharte, Manish Kumar Singh, and Maria Carla Parrini. "A Biologist-Friendly Method to Analyze Cross-Correlation Between Protrusion Dynamics and Membrane Recruitment of Actin Regulators." In Methods in Molecular Biology, 279–89. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7701-7_20.
Froud, Julie, Rebecca Boden, Anthony Ogus, and Peter Stubbs. "Compliance Cost Assessment in Action." In Controlling the Regulators, 33–54. London: Palgrave Macmillan UK, 1998. http://dx.doi.org/10.1007/978-1-349-14632-1_3.
Roberts, Jeremy A., and Richard Hooley. "Mechanisms of Action — Towards a Molecular Understanding." In Plant Growth Regulators, 151–63. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4615-7592-4_10.
Oda, Toshiro, Heiko Stegmann, Rasmus R. Schröder, Keiichi Namba, and Yuichiro Maéda. "Modeling of the F-Actin Structure." In Regulatory Mechanisms of Striated Muscle Contraction, 385–401. Tokyo: Springer Japan, 2007. http://dx.doi.org/10.1007/978-4-431-38453-3_32.
Kormendi, Roger C., Victor L. Bernard, S. Craig Pirrong, and Edward A. Snyder. "The Timeliness of Regulatory Action." In Crisis Resolution in the Thrift Industry, 19–25. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-0735-5_3.
Cramer, Michael M. "Regulatory Inspection and Control Action." In Food Plant Sanitation, 35–56. 3rd ed. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780429294341-2.
Sassenberg, Kai, and Michael L. W. Vliek. "Self-Regulation Strategies and Regulatory Fit." In Social Psychology in Action, 51–64. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-13788-5_4.
Stanisic, Mirjana, and Jelena Nedeljkovic. "Regulatory Framework of Forestry for Climate Change Mitigation and Adaptation." In Climate Action, 751–63. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-95885-9_74.
Novella, Marta Abegón. "EU regulatory action on maritime emissions." In Deploying the European Green Deal, 34–51. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003390510-3.
Schrader, J. W., K. B. Leslie, I. Clark-Lewis, P. Pitha-Rowe, H. J. Ziltener, and B. F. Fazekas. "Regulatory Polypeptides in the Lympho-Hemopoietic System." In Molecular Basis of Lymphokine Action, 245–60. Totowa, NJ: Humana Press, 1987. http://dx.doi.org/10.1007/978-1-4612-4598-8_23.
Conference papers on the topic "Actin regulators":
Paez, Alejandra V., Carla Pallavicini, Federico Schuster, Jimena Giudice, Pia Valacco, Estefania Labanca, Nicolas Anselmino, et al. "Abstract 5058: Hitting the brakes on the migratory capacity of tumoral cells: Targeting key regulators of actin dynamics in prostate cancer." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-5058.
Han, Sangyoon, and Nathan J. Sniadecki. "The Coupled Influences of Substrate Stiffness and Cell Spreading Area on Traction Force." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206523.
Nijhawan, Sunil. "Regulatory Actions That Hinder Development of Effective Risk Reduction Measures by the Nuclear Industry for Enhanced Severe Accident Prevention and Mitigation Measures After Fukushima." In 2016 24th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/icone24-60700.
Werner, H. "Fast output sampling regulators with integral action." In 1999 European Control Conference (ECC). IEEE, 1999. http://dx.doi.org/10.23919/ecc.1999.7099358.
Doroș, Diana. "The concept of child pornography. Regulatory instruments." In Simpozion stiintific al tinerilor cercetatori, editia 20. Academy of Economic Studies of Moldova, 2023. http://dx.doi.org/10.53486/9789975359030.07.
Ni, Zijing. "Regulatory capture: A rational action in business." In 2011 International Conference on E-Business and E-Government (ICEE). IEEE, 2011. http://dx.doi.org/10.1109/icebeg.2011.5877048.
McGregor, Marié. "Can workplace efficiency and safety trump affirmative action?" In Annual International Conference on Law, Regulations and Public Policy. Global Science & Technology Forum (GSTF), 2014. http://dx.doi.org/10.5176/2251-3809_lrpp14.01.
Foster, Jack W., and John V. Kauffman. "Generic Issues Program Overview and Update." In 16th International Conference on Nuclear Engineering. ASMEDC, 2008. http://dx.doi.org/10.1115/icone16-48245.
YaGOVENKO, Tat'yana, Natal'ya ZAYCEVA, and Larisa Troshina. "Growth regulators’ action on grain yield formation of white lupin." In Multifunctional adaptive feed production 27 (75). ru: Federal Williams Research Center of Forage Production and Agroecology, 2022. http://dx.doi.org/10.33814/mak-2022-27-75-73-82.
Mollo, Giovanni. "Financial Market Regulators and Crisis of Pandemic." In The 8th International Scientific Conference of the Faculty of Law of the University of Latvia. University of Latvia Press, 2022. http://dx.doi.org/10.22364/iscflul.8.2.35.
Reports on the topic "Actin regulators":
Sadot, Einat, Christopher Staiger, and Mohamad Abu-Abied. Studies of Novel Cytoskeletal Regulatory Proteins that are Involved in Abiotic Stress Signaling. United States Department of Agriculture, September 2011. http://dx.doi.org/10.32747/2011.7592652.bard.
Wiser, R., S. Pickle, and C. Goldman. California renewable energy policy and implementation issues: An overview of recent regulatory and legislative action. Office of Scientific and Technical Information (OSTI), September 1996. http://dx.doi.org/10.2172/409898.
Coalgate, J. RCRA corrective action permit requirements and modifications under Subpart F regulations. RCRA Information Brief. Office of Scientific and Technical Information (OSTI), July 1993. http://dx.doi.org/10.2172/10133317.
Boonyaratanakornkit, Viroj. Chromatin HMG-I (Y) as a Co-regulatory Protein for Estrogen Receptor Action in Breast Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, May 1999. http://dx.doi.org/10.21236/ada368525.
Boonyaratanakornkit, Viroj. Chromatin HMG-I(Y) as a Co-Regulatory Protein for Estrogen Receptor Action in Breast Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, April 2000. http://dx.doi.org/10.21236/ada391523.
Hotz-Hart, Beat. Thematic synthesis “Market Conditions and Regulation” of the NRP “Energy”. Swiss National Science Foundation (SNSF), November 2019. http://dx.doi.org/10.46446/publication_nrp70_nrp71.2019.4.en.
David, Gabrielle, D. Somerville, Julia McCarthy, Spencer MacNeil, Faith Fitzpatrick, Ryan Evans, and David Wilson. Technical guide for the development, evaluation, and modification of stream assessment methods for the Corps Regulatory Program. Engineer Research and Development Center (U.S.), October 2021. http://dx.doi.org/10.21079/11681/42182.
Trabalka, J. R. Developing a strategy and closure criteria for radioactive and mixed waste sites in the ORNL remedial action program: Regulatory interface. Office of Scientific and Technical Information (OSTI), September 1987. http://dx.doi.org/10.2172/6126203.
Ingram, Michael, David Narang, Daniella Rough, Peyton Sanders, Hallie Lucas, Andres Dominguez, and Carolina Obando Anzola. USAID Colombia Young Leaders Workforce Training Program Action Plans: Regulatory Road Map for Distributed Energy Resource (DER) Interconnection and Interoperability. Office of Scientific and Technical Information (OSTI), April 2023. http://dx.doi.org/10.2172/1969538.
Bustos, Sebastián, Luis Felipe Céspedes, John Leon-Diaz, and María Orduz. From Discussion to Action: Characterizing Areas of Reform in Latin America and the Caribbean. Inter-American Development Bank, September 2023. http://dx.doi.org/10.18235/0005171.