Academic literature on the topic 'Acelerated Bone fracture healing'

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Journal articles on the topic "Acelerated Bone fracture healing"

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Smith, Robert G. "Fracture Healing." Journal of the American Podiatric Medical Association 105, no. 2 (March 1, 2015): 160–72. http://dx.doi.org/10.7547/0003-0538-105.2.160.

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Background Recognizing the existence of adverse drug effects of frequently prescribed drugs can empower a clinician with knowledge to avoid dangerous adverse effects that may result in hazardous, negative patient outcomes on either fracture healing or bone health. Pharmacovigilance reports have described the influence of medications, allowing for bone health to be quite unpredictable. Methods First, mechanisms found in the medical literature of potential drug adverse effects regarding fracture healing are presented. Second, the 100 most frequently prescribed medications in 2010 are reviewed regarding adverse effects on fracture healing. These reported adverse effects are evaluated for medical causation. Last, a data table describing the 100 reviewed medications and their reported effects on fracture healing is provided. Results The actual number of different medications in the review was 72. Reported drug adverse effects on bone and fracture healing occurred with 59 of the 72 drugs (81.9%). These adverse effects are either described as a definitive statement or represented by postmarketing case reports. Thirteen of the 72 review drugs (18.1%) did not have any description of the possible effects on bone health. A total of 301 cases reports describing delayed union, malunion, and nonunion of fractures represent 31 of the 72 medications reviewed (43.1%). Conclusions This review offers the health-care provider information regarding potential adverse drug effects on bone health. Empowered with this information, clinicians may assist their patients in maximizing pharmacologic outcomes by avoiding these reported harmful adverse effects.
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Cornell, Charles, and Gregory S. DiFelice. "Fracture healing in osteoporotic bone." Current Opinion in Orthopaedics 7, no. 5 (October 1996): 12–15. http://dx.doi.org/10.1097/00001433-199610000-00003.

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Richards, Mark, James A. Goulet, Jeffrey A. Weiss, Nicholas A. Waanders, Mitchell B. Schaffler, and Steven A. Goldstein. "Bone Regeneration and Fracture Healing." Clinical Orthopaedics and Related Research 355S (October 1998): S191—S204. http://dx.doi.org/10.1097/00003086-199810001-00020.

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Cheung, Wing Hoi, Theodore Miclau, Simon Kwoon-Ho Chow, Frank F. Yang, and Volker Alt. "Fracture healing in osteoporotic bone." Injury 47 (June 2016): S21—S26. http://dx.doi.org/10.1016/s0020-1383(16)47004-x.

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Ono, Takehito, and Hiroshi Takayanagi. "Osteoimmunology in Bone Fracture Healing." Current Osteoporosis Reports 15, no. 4 (June 24, 2017): 367–75. http://dx.doi.org/10.1007/s11914-017-0381-0.

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Giannoudis, Peter V., Elena Jones, and Thomas A. Einhorn. "Fracture healing and bone repair." Injury 42, no. 6 (June 2011): 549–50. http://dx.doi.org/10.1016/j.injury.2011.03.037.

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Mick, Paul, and Christian Fischer. "Delayed Fracture Healing." Seminars in Musculoskeletal Radiology 26, no. 03 (June 2022): 329–37. http://dx.doi.org/10.1055/s-0041-1740380.

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AbstractPhysiologic bone healing involves numerous parameters, such as microstability, fracture morphology, or tissue perfusion, to name just a few. Slight imbalances or a severe impairment of even one of these factors may, as the figurative weakest link in the chain, crucially or completely inhibit the regenerative potential of a fractured bone. This review revisits the physiology and pathophysiology of fracture healing and provides an insight into predispositions, subtypes, diagnostic tools, and therapeutic principles involved with delayed fracture healing and nonunions. Depending on the patients individual risk factors, nonunions may develop in a variety of subtypes, each of which may require a slightly or fundamentally different therapeutical approach. After a detailed analysis of these individual factors, additional diagnostic tools, such as magnetic resonance imaging (MRI), dynamic contrast-enhanced MRI, sonography, or contrast-enhanced ultrasonography, may be indicated to narrow down the most likely cause for the development of the nonunion and therefore help find and optimize the ideal treatment strategy.
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Deguine, Christian, and Jack L. Pulec. "Temporal Bone Fracture following Spontaneous Healing." Ear, Nose & Throat Journal 82, no. 6 (June 2003): 414. http://dx.doi.org/10.1177/014556130308200604.

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Protopappas, V. C., M. G. Vavva, D. I. Fotiadis, and K. N. Malizos. "Ultrasonic monitoring of bone fracture healing." IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 55, no. 6 (June 2008): 1243–55. http://dx.doi.org/10.1109/tuffc.2008.787.

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Johnson, Mark A. "Biochemical bone fracture healing process model." IFAC Proceedings Volumes 36, no. 15 (August 2003): 335–40. http://dx.doi.org/10.1016/s1474-6670(17)33525-5.

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Dissertations / Theses on the topic "Acelerated Bone fracture healing"

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Richardson, James Bruce. "The mechanics of fracture healing." Thesis, University of Aberdeen, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.290866.

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The mechanics applied to healing fractures vary widely. At one extreme rigid internal fixation is advocated, while at the other early mobilisation is recommended using external splints. Kuhn's method of paradigm orientated research was used to define the historical context of current assumptions regarding fracture healing. Conflict between the various schools of thought is the main evidence for failure of these assumptions and the need to evolve a new perspective on fracture healing. A paradigm is presented which proposes healing by external callus as an early stage and 'primary healing' as the later stage as of one continuous but changing process. A fundamental hypothesis was tested: that mechanics is the major control of fracture healing in man. A multicentre study of 102 patients with serious fractures were treated with external skeletal fixation. In 60 patients rigid external fixation was applied. In the remaining 42 the same fixation device was used, but adapted to apply 1 to 2mm of cyclic axial micromovement across the fracture. A piston applied 500 cycles of movement over a 30 minute period each day until this could be achieved by the patient on weight-bearing. Objective assessment required development of new techniques of measuring fracture stiffness and defining the point of healing. This objective measure, and clinically defined healing, were significantly faster in the group treated with micromovement (two-way analysis of variance, p = 0.005 and 0.03, respectively). Repeated injury by plastic deformation is proposed to maintain callus growth in the first phase of healing. Evidence for the required parameters of movement was gathered from the trial of micromovement, from measurements in 4 cases of epiphyseolysis and also 8 patients undergoing arthrodesis. It would appear appropriate to apply cyclic axial displacement of 2mm within the first two weeks from injury and of consistent direction until sufficient bulk of callus is formed. Thereafter axial compaction is appropriate in a second phase where callus matures. The mechanics that govern remodelling were considered to apply to the final phase. Failure of a cell culture model to display obvious results from cyclic loading may indicate that the response to mechanical loading is indirect. Intermediate and mechanically dependent biochemical and bioelectrical factors are discussed.
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Li, Jiang, and 李江. "Bone fracture healing in laminopathy-based premature aging." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45142233.

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Yew, Alvin Garwai. "The equilibrium geometry theory for bone fracture healing." College Park, Md. : University of Maryland, 2008. http://hdl.handle.net/1903/8308.

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Thesis (M.S.) -- University of Maryland, College Park, 2008.
Thesis research directed by: Dept. of Mechanical Engineering. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Mawhinney, Ian Nicholas. "Bone and ultrasound." Thesis, Queen's University Belfast, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335942.

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Manitzky, Louise J. "Mathematical modelling of intramembranous bone formation during fracture healing." Thesis, Queensland University of Technology, 2014. https://eprints.qut.edu.au/78983/1/Louise_Manitzky_Thesis.pdf.

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During fracture healing, many complex and cryptic interactions occur between cells and bio-chemical molecules to bring about repair of damaged bone. In this thesis two mathematical models were developed, concerning the cellular differentiation of osteoblasts (bone forming cells) and the mineralisation of new bone tissue, allowing new insights into these processes. These models were mathematically analysed and simulated numerically, yielding results consistent with experimental data and highlighting the underlying pattern formation structure in these aspects of fracture healing.
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Mahmud, Fares A. "The electromechanical properties of bone." Thesis, Staffordshire University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.254325.

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Watkins, P. E. "A study of mechanical influences on fracture healing, and on fracture non-union." Thesis, University of Bristol, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376622.

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Murray, Alastair W. "Fracture healing in osteopenic bone and the influence of simvastatin." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/29286.

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In part one of the study 20, 3-month-old female, Wistar rats underwent ovariectomy (Ovx) while a further 20 had a sham procedure to act as controls. Seven weeks later a transverse fracture was created in the proximal tibia of each animal by three-point bending with the resulting fractures supported by an intramedullary wire. Half of the animals in each group were euthanased at two weeks and the remainder at four weeks post fracture with tibiae removed post mortem. All tibiae were then x-rayed. The mechanical properties of half of the healing fractures were ascertained by four-point bending to failure while the remaining specimens were prepared for histological analysis and immunohistochemistry. There were no mechanical differences in the fracture calluses from the ovx animals compared with control at two weeks but by four weeks post fracture the ultimate load at failure of the fractures from the ovx animals were rescued to 71% of that from controls. Stiffness (54%) and stress at yield (74%) were also reduced while the strain at yield was increased by 40% in fractures from the ovx group. In the second part of the study the same animal model was used with the groups once again divided into ovx and sham controls. Half of each group received placebo while the other half received simvastatin 20mg/kg daily for 14 days post fatigue. The same time points and outcome measures were used as in the first part of the study. The dose and method of delivery of simvastatin had no apparent effect on the fracture healing in normal bone. However simvastatin appeared to have a deleterious effect on fracture healing in the osteopenic model causing a reduction in callus size and maturity and reducing the healing fractures’ ability to withstand load. This study does not support a role for simvastatin in the enhancement of fracture healing in osteopenia.
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Kaluarachchi, Thambilipitiyage Kusumsiri Priyantha Kumara. "Impact of collagen type X deficiency on bone fracture healing." Thesis, Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23501807.

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Nyquist, Fredrik. "The influence of alcohol on bone metabolism and fracture healing." Lund : Lund University, Dept. of Orthopaedics, Malmö University Hospital, 1998. http://catalog.hathitrust.org/api/volumes/oclc/39792795.html.

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Books on the topic "Acelerated Bone fracture healing"

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D, Johnson Kenneth, ed. Biomechanics in orthopedic trauma: Bone fracture and fixation. London: M. Dunitz, 1994.

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Mehta, Samir. Orthobiologics: Improving fracture care through science. Philadelphia: Wolters Kluwer Health/Lippincott Wiliams & Wilkins, 2007.

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Behari, Jitendra. Biophysical bone behavior. Singapore: John Wiley, 2009.

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Charnley, John. The Closed treatment of common fractures. 4th ed. Cambridge: Colt Books in association with The John Charnley Trust, 1999.

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A, Martinez Steven, ed. Fracture management and bone healing. Philadelphia: W.B. Saunders, 1999.

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Orthobiologics: Improving Fracture Care Through Science. Lippincott Williams & Wilkins, 2007.

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Angela, Ryan. Healing Bone Fractures: Complete Guide on Bone Fracture Treatment for Your Complete Health Benefits. Independently Published, 2021.

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A, Einhorn Thomas, Lane Joseph M. 1939-, and Association of Bone and Joint Surgeons., eds. Association of Bone and Joint Surgeon Workshop Supplement: Fracture healing enhancement. Hagerstown, Md: Lippincott Williams & Wilkins, 1998.

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Charnley, John. The Closed Treatment of Common Fractures. 4th ed. Greenwich Medical Media Ltd, 1999.

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Microvascular Bone Reconstruction. Taylor & Francis, 1997.

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Book chapters on the topic "Acelerated Bone fracture healing"

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Bartl, Reiner, and Christoph Bartl. "Fracture Healing." In Bone Disorders, 239–42. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29182-6_35.

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De Marchi, Armanda, Davide Orlandi, Enzo Silvestri, Luca Cavagnaro, and Alessandro Muda. "Bone Fracture Healing." In Musculoskeletal Ultrasound in Orthopedic and Rheumatic disease in Adults, 215–18. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-91202-4_24.

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Haffner, Nicolas, Daniel Smolen, and Rainer Mittermayr. "Fracture Healing." In Principles of Bone and Joint Research, 99–124. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-58955-8_7.

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Protopappas, Vasilios C., Maria G. Vavva, Konstantinos N. Malizos, Demos Polyzos, and Dimitrios I. Fotiadis. "Ultrasonic Monitoring of Fracture Healing." In Bone Quantitative Ultrasound, 361–79. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-94-007-0017-8_14.

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Iyer, K. Mohan. "Anatomy of Bone, Fracture, and Fracture Healing." In General Principles of Orthopedics and Trauma, 1–17. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-15089-1_1.

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Iyer, K. Mohan. "Anatomy of Bone, Fracture, and Fracture Healing." In General Principles of Orthopedics and Trauma, 1–11. London: Springer London, 2012. http://dx.doi.org/10.1007/978-1-4471-4444-1_1.

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Augat, Peter, and James T. Ryaby. "Fracture Healing and Micro Architecture." In Noninvasive Assessment of Trabecular Bone Architecture and the Competence of Bone, 99–110. Boston, MA: Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-0651-5_11.

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Kakar, Sanjeev, and Thomas A. Einhorn. "Importance of Nutrition in Fracture Healing." In Nutrition and Bone Health, 85–103. Totowa, NJ: Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-740-6_5.

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Sela, Jona J., and Itai A. Bab. "Healing of Bone Fracture: General Concepts." In Principles of Bone Regeneration, 1–8. Boston, MA: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-2059-0_1.

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Morgan, Elise F., and Thomas A. Einhorn. "Biomechanics of Fracture Healing." In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 99–105. Ames, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118453926.ch12.

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Conference papers on the topic "Acelerated Bone fracture healing"

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Kimura, Satoshi, Keisuke Oe, Yohei Kumabe, Tomoaki Fukui, Takahiro Niikura, Ryosuke Kuroda, Naomi Yagi, and Yutaka Hata. "Ultrasonic Diagnosis for Bone Fracture Healing Process." In 2020 IEEE 50th International Symposium on Multiple-Valued Logic (ISMVL). IEEE, 2020. http://dx.doi.org/10.1109/ismvl49045.2020.00-37.

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Kimura, Satoshi, Keisuke Oe, Yohei Kumabe, Tomoaki Fukui, Takahiro Niikura, Ryosuke Kuroda, Naomi Yagi, and Yutaka Hata. "Ultrasonic Diagnosis for Bone Fracture Healing Process." In 2020 IEEE 50th International Symposium on Multiple-Valued Logic (ISMVL). IEEE, 2020. http://dx.doi.org/10.1109/ismvl49045.2020.00-37.

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Kaufman, J. J., A. Chiabrera, N. Hakim, M. Hatem, M. Figueiredo, P. Nasser, S. Lattuga, P. Trent, A. A. Pilla, and R. S. Siffert. "Bone fracture healing assessment using a neural network." In 1990 IJCNN International Joint Conference on Neural Networks. IEEE, 1990. http://dx.doi.org/10.1109/ijcnn.1990.137694.

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Ueyama, Takumi, Yohei Kumabe, Keisuke Oe, Tomoaki Fukui, Takahiro Niikura, Ryosuke Kuroda, Masakazu Morimoto, Naomi Yagi, and Yutaka Hata. "On Degree of Bone Healing for Bone Fracture Treatment by Ultrasonic Wave." In 2021 International Conference on Machine Learning and Cybernetics (ICMLC). IEEE, 2021. http://dx.doi.org/10.1109/icmlc54886.2021.9737253.

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Zuniga, A., A. Babakhanov, C. Mahajan, and M. Nikish. "Fracture Track Bone Healing Measurement through an External Fixator." In 2013 39th Annual Northeast Bioengineering Conference (NEBEC). IEEE, 2013. http://dx.doi.org/10.1109/nebec.2013.97.

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Kojouharov, H. V., I. Trejo, and B. M. Chen-Charpentier. "Modeling the effects of inflammation in bone fracture healing." In APPLICATION OF MATHEMATICS IN TECHNICAL AND NATURAL SCIENCES: 9th International Conference for Promoting the Application of Mathematics in Technical and Natural Sciences - AMiTaNS’17. Author(s), 2017. http://dx.doi.org/10.1063/1.5007359.

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Tschaffon, M., S. Foertsch, E. Kempter, A. Ignatius, M. Haffner-Luntzer, and SO Reber. "Chronic psychosocial stress disturbs bone homeostasis and fracture healing." In 1. MuSkITYR Symposium. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1700645.

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Irandoust, Soroush, and Sinan Muftu. "Effects of numerical parameters used in bone fracture healing simulations." In 2014 40th Annual Northeast Bioengineering Conference (NEBEC). IEEE, 2014. http://dx.doi.org/10.1109/nebec.2014.6972821.

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Wehrbein, Randol, and Aleksander P. McElroy. "EVIDENCE OF THE OLDEST HEALING LIMB BONE FRACTURE IN AMNIOTES." In 52nd Annual GSA South-Central Section Meeting - 2018. Geological Society of America, 2018. http://dx.doi.org/10.1130/abs/2018sc-310016.

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Trejo, I., H. V. Kojouharov, and B. M. Chen-Charpentier. "Modeling the effects of growth factors on bone fracture healing." In APPLICATION OF MATHEMATICS IN TECHNICAL AND NATURAL SCIENCES: 11th International Conference for Promoting the Application of Mathematics in Technical and Natural Sciences - AMiTaNS’19. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5130790.

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Reports on the topic "Acelerated Bone fracture healing"

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Gerstenfeld, Louis C. Assessment of the Genetic Variation in Bone Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada471462.

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Gerstenfeld, Louis C. Assessment of the Genetic Variation in Bone Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada471893.

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Weinhold, Paul, and Laurence Dahners. Desferrioxamine for Stimulation of Fracture Healing and Revascularization in a Bone Defect Model. Fort Belvoir, VA: Defense Technical Information Center, February 2012. http://dx.doi.org/10.21236/ada562175.

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Baylink, David J. Molecular Mechanisms of Soft Tissue Regeneration and Bone Formation in Mice: Implications in Fracture Repair and Wound Healing in Humans. Fort Belvoir, VA: Defense Technical Information Center, October 2003. http://dx.doi.org/10.21236/ada420947.

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Baylink, David J. Molecular Mechanisms of Soft Tissue Regeneration and Bone Formation in Mice: Implications in Fracture Repair and Wound Healing in Humans. Fort Belvoir, VA: Defense Technical Information Center, October 2000. http://dx.doi.org/10.21236/ada391335.

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Mohan, Subburaman. Molecular Mechanisms of Soft Tissue Regeneration and Bone Formation in Mice: Implication in Fracture Repair and Wound Healing in Humans. Fort Belvoir, VA: Defense Technical Information Center, April 2008. http://dx.doi.org/10.21236/ada482393.

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