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Dissertations / Theses on the topic 'Abdominal aneurysm'

Author: Grafiati
Published: 4 June 2021
Last updated: 29 January 2023

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1

Rossaak, Jeremy Ian, and n/a. "The genetics of abdominal aortic aneurysms." University of Otago. Dunedin School of Medicine, 2004. http://adt.otago.ac.nz./public/adt-NZDU20070502.143818.

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Abdominal Aortic Aneurysms (AAA) are amongst the top ten most common cause of death in those over 55 years of age. The disease is usually asymptomatic, often being diagnosed incidentally. Once diagnosed, elective repair of an AAA results in excellent long-term survival with a 3-5% operative mortality. However, up to one half of patients present with ruptured aneurysms, a complication that carries an 80% mortality in the community, and of those reaching hospital, a 50% mortality. Clearly early diagnosis and treatment results in improved survival. Screening for AAA, with ultrasound, would dete
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2

Svensjö, Sverker. "Screening for Abdominal Aortic Aneurysm." Doctoral thesis, Uppsala universitet, Kärlkirurgi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-198677.

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Randomised controlled trials have demonstrated that mortality from Abdominal Aortic Aneurysm (AAA) can be cost-effectively reduced by ultrasound-screening of men. Evidence for screening women is insufficient. Reports of falling AAA incidence are emerging. In an effort to study screening for AAA in a contemporary setting, two cross-sectional multi-centre population-based studies of one-time screening of 65-year-old men, and 70-year-old women in Middle Sweden were undertaken. Cost-efficiency of one-time screening of 65-year-old men was evaluated in a decision-analysis model. Five-year outcomes i
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3

Chinien, Ganessen. "Molecular genetics of abdominal aortic aneurysm." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/molecular-genetics-of-abdominal-aortic-aneurysm(e269485a-e71a-41a7-9a8e-ae40eb968dd4).html.

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Abdominal aortic aneurysm (AAA) is a common disorder and a major cause of death. Pathological processes involved in AAA formation include inflammation, proteolysis, angiogenesis and apoptosis. It has also a strong familial predisposition with linkage studies identifying chromosomes 19q13 and 4q31 as susceptible loci. AAA is likely to be a polygenic disorder. Aims The aims of this study were to carry out a whole transcriptome analysis in order to identify novel genes and pathways that are differentially expressed between aneurysmal (AAA), atheromatous (AOD) and normal (NA) aortic tissue and to
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4

Malina, Martin. "Endovascular repair of abdominal aortic aneurysms aspects on a novel technique /." Lund : Dept. of Vascular and Renal Diseases, Lund University, Malmö University Hospital, 1998. http://books.google.com/books?id=hWBsAAAAMAAJ.

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5

Lowe, Christopher. "Three-dimensional ultrasound in the management of abdominal aortic aneurysm." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/threedimensional-ultrasound-in-themanagement-of-abdominal-aorticaneurysm(b8950db7-847b-4d11-a6a5-2a06b3bb66d0).html.

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Objectives: Clinical implementation of 3D ultrasound (3D-US) in vascular surgery is in its infancy. The aim of this thesis was to develop novel clinical applications for 3D-US in the diagnosis and management of abdominal aortic aneurysm (AAA). Methods: Four principle clinical applications were investigated. 1) Intraoperative imaging – The ability of 3D-US to detect and classify endoleaks was compared with digital subtraction angiography in patients undergoing EVAR. 2) Detection and classification of endoleaks following endovascular aneurysm repair (EVAR) – The abilityof 3D-US to accurately det
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6

Djavani, Gidlund Khatereh. "Intra-abdominal Hypertension and Colonic Hypoperfusion after Abdominal Aortic Aneurysm Repair." Doctoral thesis, Uppsala universitet, Institutionen för kirurgiska vetenskaper, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-149241.

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Colonic ischaemia (CI), Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are devastating complications after abdominal aortic aneurysm (AAA) surgery. The aims of this thesis were to study the incidence and clinical consequences of IAH/ACS and the association between CI and intra-abdominal pressure (IAP) among patients undergoing OR for ruptured AAA (rAAA), to compare extraluminal pHi monitoring, with standard intra-luminal monitoring among patients operated on for AAA, and to study the frequency and clinical consequences of IAH/ACS after endovascular repair (EVAR) fo
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7

Boyle, Jonathan Robert. "New perspectives in abdominal aortic aneurysm management." Thesis, University of Leicester, 2000. http://hdl.handle.net/2381/29606.

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A better understanding of the pathophysiology of abdominal aortic aneurysms has recently been established paving the way for potential targeted pharmacotherapy aimed at inhibiting the growth of small aneurysms. In particular the matrix metallopropteinase enzymes have been implicated in the destruction of the aortic wall. To this end the first part of this thesis investigates the potential therapeutic role of doxycycline, a non-specific metalloproteinase inhibitor, in an established model of aneurysmal disease. Subsequently the role of Amlodipine a calcium antagonist and metalloproteinase poten
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8

Choke, Tieng Chek. "Molecular mechanisms of abdominal aortic aneurysm rupture." Thesis, St George's, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511897.

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9

Watton, Paul N. "Mathematical modelling of the abdominal aortic aneurysm." Thesis, University of Leeds, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411948.

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10

Holmström, Ami. "Abdominal Aortic Aneurysm Screening : an Ethical Discussion." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-72994.

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Introduction: Abdominal aortic aneurysms (AAA) have a prevalence of approximately 2%, and are more common in men. AAAs are generally asymptomatic, but if ruptured and untreated, the mortality rate is close to 100%. Screening programs for AAAs are implemented in Sweden, the UK, and the US. This study describes the different views of AAA screening with a special emphasis on underlying ethical issues. Aim: To analyze the scientific background of AAA screening in order to be able to discuss its ethical basis. Methods: This was a qualitative literature study with an analysis of arguments using a he
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11

Abbas, Abeera. "Multimodality imaging of the abdominal aortic aneurysm." Thesis, King's College London (University of London), 2015. http://kclpure.kcl.ac.uk/portal/en/theses/multimodality-imaging-of-the-nabdominal-aortic-aneurysm(fcdd75c2-eb72-4623-9529-515004d32d8d).html.

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Age and hypertension lead to aortic remodeling and stiffness and are also major risk factors for abdominal aortic aneurysms (AAA). This study aimed to investigate: (i) the use of multimodal imaging to test the hypothesis that aneurysmal disease of the abdominal aorta is a remodeling response to aortic stiffness and systolic hypertension; (ii) the utility of a novel ultrasound-based device (AortaScan) for detection of AAA in the community setting. We used multimodality imaging tonometry and cardiovascular magnetic resonance imaging (CMR) to quantify pulse wave velocity (PWV, a measure of stiffn
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12

Bailey, Marc Aaron. "Store operated calcium entry in abdominal aortic aneurysm." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/13678/.

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Background: Abdominal Aortic Aneurysm (AAA) is a focal dilatation of the abdominal aorta that progresses over time and eventually ruptures. Surgery is risky but a medical therapy is lacking. Vascular smooth muscle cells (VSMC) are apoptotic in end-stage AAA. There is evidence that they undergo pathological remodelling in early disease. My novel hypothesis is that reduction of this pathological vascular remodelling will be beneficial. Platelet derived growth factor (PDGF) drives VSMC remodelling through IP3 generation, ER Ca2+ store release and store operated Ca2+ entry (SOCE) via the plasma me
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13

Tambyraja, Andrew Laksman. "Prediction of outcome after abdominal aortic aneurysm rupture." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/29391.

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Existing risk models and predictive variables for outcome were validated on a retrospective cohort of consecutive patients with ruptured AAA. These data were also used to design novel prognostic index for outcome prediction. A prospective cohort of consecutive patients was used to further validate these scoring systems, examine novel prognostic variables and determine functional outcome. Existing risk scoring instruments for patients with ruptured AAA lack validity. Analysis of preoperative variables in patients with ruptured AAA shows that absolute surgical futility cannot be predicted. Howev
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14

Tegler, Gustaf. "Abdominal Aortic Aneurysm : Molecular Imaging Studies of Pathophysiology." Doctoral thesis, Uppsala universitet, Kärlkirurgi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-194663.

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The pathological process behind abdominal aortic aneurysm (AAA) formation is poorly understood and difficult to study. The aim of the thesis was to study the pathophysiology of AAA formation with positron emission tomography (PET) technology, a molecular imaging technique, allowing in vivo studies of pathophysiological changes. In study I 18F-FDG, a glucose analogue, was tested. It had previously been reported as a useful tracer studying inflammation in AAAs. These studies included, however, foremost large, symptomatic, and inflammatory AAAs. In the present study on five small and seven large
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15

Olofsson, Anna. "Capturing circulating microRNAs in abdominal aortic aneurysm disease." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-296450.

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The current study focuses on finding differential expression between circulating microRNAs in plasma from patients with abdominal aortic aneurysms compared to un-diseased individuals by using a qPCR-based array. In addition, we evaluated the expression of deregulated microRNAs in human tissue samples as well as microarray data from two independent mouse models of aneurysm development. Fifteen miRNAs were found to be significantly differentially expressed, with four of them surviving multiple testing. Interestingly all four of them were substantially different in murine aneurysm development.
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16

Potseluev, V., and M. Kora. "Anesthesia in endovascular abdominal aortic aneurysm (AAA) repair." Thesis, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/58598.

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Introduction: endovascular AAA repair can be done using different anesthetic techniques, such as general anesthesia, regional block, and local anesthesia associated with sedation. For successful anesthetic management, it is important to select the best approach with an understanding of the patient's health status.
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17

Mani, Kevin. "Abdominal aortic aneurysm epidemiological and health economic aspects /." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110810.

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18

Mello, Flávia Moerbeck Casadei de [UNESP]. "Aneurisma da aorta abdominal infra-renal: avaliação ultra-sonográfica em homens acima de 50 anos." Universidade Estadual Paulista (UNESP), 2003. http://hdl.handle.net/11449/87358.

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Made available in DSpace on 2014-06-11T19:22:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2003Bitstream added on 2014-06-13T19:08:21Z : No. of bitstreams: 1 mello_fmc_me_botfm.pdf: 590394 bytes, checksum: 6bd49179dbdb5496cc2a8f6a9ebad2ed (MD5)<br>Com o objetivo de avaliar a ocorrência de aneurisma da aorta abdominal infra-renal (AAAIR), estudou-se uma amostra da população masculina do Município de Marília, com idade igual ou acima de 50 anos, no período de 2000 a 2002. Foram avaliados 240 homens por meio da ultrasonografia abdominal (USAb), com média de idade de 65,1 anos (±9,8 anos)
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19

Tenório, Emanuel Júnio Ramos. "Expressão dos níveis plasmáticos dos miRNA-191 e miRNA-455-3P em pacientes com aneurisma de aorta abdominal e suas relações com a evolução clínica após tratamento endovascular." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17137/tde-10042018-142246/.

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Introdução: O aneurisma de aorta abdominal (AAA) é uma importante causa de morbimortalidade na população idosa. O tratamento endovascular está associado a menor morbimortalidade que o tratamento convencional, no entanto, necessita de um seguimento rigoroso com exames de imagem contrastados para confirmação da exclusão do saco aneurismático. Considerando que a formação de um aneurisma é um processo multifatorial complexo, envolvendo a remodelação destrutiva do tecido conjuntivo em todo o segmento afetado da parede da aorta e que este processo envolve uma inflamação crônica local, uma diminuição
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20

Gopalakrishnan, Shyam Sunder. "Dynamics and Stability of Flow through Abdominal Aortic Aneurysms." Doctoral thesis, Université de Lyon 1, Ecole Centrale de Lyon, Lyon, 2014. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/245358.

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21

Brekken, Reidar. "Ultrasound-based Estimation of Strain in Abdominal Aortic Aneurysm." Doctoral thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for sirkulasjon og bildediagnostikk, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-19999.

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Abdominal aortic aneurysm (AAA) is a vascular disease resulting in a permanent local dilatation of the abdominal aorta. Different studies estimate the prevalence of AAA to 1.3-8.9% of men and 1.0-2.2% of women over 60 years of age. Risk factors include smoking, hypertension, high serum cholesterol, diabetes, and family history. The weakening of the wall and altered wall stress associated with aneurysm formation and progression may eventually lead to aneurysm rupture, which causes haemorrhage and severe blood loss and is associated with very high mortality. AAA is responsible for 1.3% of deaths
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22

Chamberlain, Ciara M. "Granzyme B in abdominal aortic aneurysm and aortic dissection." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/5584.

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An aneurysm is a permanent focal dilatation of an artery, often associated with atherosclerosis and with a weakening of the vessel wall. An arterial dissection is when a tear in the inner layer of the blood vessel causes blood to flow between the layers and force the blood vessel apart. Aneurysms or dissections can result in rupturing of the vessel, leading to excessive hemorrhaging and death if not immediately repaired. Granzyme B (GrB) is a protein that is expressed and secreted by cytotoxic immune cells. GrB has been identified as a key player in atherosclerosis both in the induction of apo
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23

Grytsan, Andrii. "Abdominal aortic aneurysm inception and evolution - A computational model." Doctoral thesis, KTH, Biomekanik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-197289.

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Abdominal aortic aneurysm (AAA) is characterized by a bulge in the abdominal aorta. AAA development is mostly asymptomatic, but such a bulge may suddenly rupture, which is associated with a high mortality rate. Unfortunately, there is no medication that can prevent AAA from expanding or rupturing. Therefore, patients with detected AAA are monitored until treatment indication, such as maximum AAA diameter of 55 mm or expansion rate of 1 cm/year. Models of AAA development may help to understand the disease progression and to inform decision-making on a patient-specific basis. AAA growth and remo
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24

Milne, Alan Anderson. "Coagulopathy and haemostasis in surgery for abdominal aortic aneurysm." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/21422.

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Coagulation studies were performed in a series of 24 patients with asymptomatic abdominal aortic aneurysm. Levels of fibrinogen were high but within the normal range, and there was no evidence of systemic activation of the soluble coagulation or fibrinolytic systems. Coagulation studies were performed in a series of six patients undergoing elective aortic aneurysm repair. It was found that thrombin, fibrinolytic and platelet activation increases during the period of initial dissection in a time dependent manner. After the administration of heparin and the application of the aortic cross clamp,
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25

Grytsan, Andrii. "Computational model of abdominal aortic aneurysm inception and evolution." Licentiate thesis, KTH, Biomekanik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-142649.

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Incidence of abdominal aortic aneurysm (AAA) is increasing in the aging society of the western world. Development of AAA is mostly asymptomatic and is characterized by a bulge in the abdominal aorta. However, AAA may suddenly rupture, which results in an internal bleeding associated with a high mortality rate. Patients with AAA undergo regular screening until treatment indication. To date, statistical criteria are used to decide whether the risk of rupture exceeds the risk of intervention. Models of AAA development help to understand the disease progression and to yield patient-specific criteri
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26

Mello, Flávia Moerbeck Casadei de. "Aneurisma da aorta abdominal infra-renal : avaliação ultra-sonográfica em homens acima de 50 anos /." Botucatu : [s.n.], 2003. http://hdl.handle.net/11449/87358.

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Orientador: Hamilton Almeida Rollo<br>Resumo: Com o objetivo de avaliar a ocorrência de aneurisma da aorta abdominal infra-renal (AAAIR), estudou-se uma amostra da população masculina do Município de Marília, com idade igual ou acima de 50 anos, no período de 2000 a 2002. Foram avaliados 240 homens por meio da ultrasonografia abdominal (USAb), com média de idade de 65,1 anos (±9,8 anos). A aorta abdominal foi medida no sentido ânteroposterior (AP) e látero-lateral (LL) aproximadamente a 2cm abaixo da artéria mesentérica superior (AMS) e 2cm acima de sua bifurcação. O critério utilizado para co
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27

Hua, Fang. "Role of angiotensin II and inflammatory cells in the development of human abdominal aortic aneurysm /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18409.pdf.

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28

Krenzien, Felix, Ivan Matia, Georg Wiltberger, et al. "Early prediction of survival after open surgical repair of ruptured abdominal aortic aneurysms." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-156960.

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Background: Scoring models are widely established in the intensive care unit (ICU). However, the importance in patients with ruptured abdominal aortic aneurysm (RAAA) remains unclear. Our aim was to analyze scoring systems as predictors of survival in patients undergoing open surgical repair (OSR) for RAAA. Methods: This is a retrospective study in critically ill patients in a surgical ICU at a university hospital. Sixty-eight patients with RAAA were treated between February 2005 and June 2013. Serial measurements of Sequential Organ Failure Assessment score (SOFA), Simplified Acute Physiology
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29

Maiellaro, Kathryn Adele. "The role of oxidative stress in abdominal aortic aneurysm development: molecular and mechanical effects in the origins of aneurysmal disease." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/24708.

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Thesis (M.S.)--Biomedical Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: W. Robert Taylor; Committee Member: John Oshinski; Committee Member: Kathy Griendling; Committee Member: Raymond P. Vito; Committee Member: Rudolph L. Gleason.
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30

Haug, Erik Skaaheim. "Infrarenal abdominal aortic aneurysm : comorbidity and results following open surgery." Doctoral thesis, Norwegian University of Science and Technology, Department of Circulation and Medical Imaging, 2005. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-1772.

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31

Hadjianastassiou, Vassilis Georgiou. "Risk stratification modelling in post-operative abdominal aortic aneurysm patients." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491903.

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Introduction: the aim of the project was to test the hypothesis that 'the principles of risk stratification modelling can be successfully applied in a combined group of both elective and emergency AAA patients in the immediate post-operative setting'. Methods: the applicability of two existing generic risk stratification models as predictors of in-hospital mortality was assessed in a combined group of elective and emergency post-operative abdominal aortic aneurysm patients, from 24 Intensive Care Units in the North-Thames. The better of the two models was chosen to develop a disease-specific r
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32

Qu, Zao, and 瞿早. "Expression of sphingosine-1-phosphate receptor in abdominal aortic aneurysm." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47050834.

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33

Ang, Lisa Shouning. "The extracellular role of granzyme B in abdominal aortic aneurysm." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/45649.

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34

Liu, Jing. "THE ROLE OF APOB-CONTAINING LIPOPROTEINS IN ABDOMINAL AORTIC ANEURYSM." UKnowledge, 2015. http://uknowledge.uky.edu/pharmacol_etds/12.

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Abdominal aortic aneurysm (AAA) is a devastating disease that exhibits permanent lumen expansion typically in the infrarenal aorta. AAA is prevalent among aged population, especially in males. Despite the incidence in women is lower, studies indicate the tortuosity is more severe and aortic rupture risk is higher in women. In most patients, AAA remains asymptomatic until it ruptures leading to sudden and fatal hemorrhage. To date, there is no proven medical therapy that can prevent the expansion or rupture. Human observational studies implicate the presence of AAA is associated with both high
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35

O'Connell, Mary Kathleen. "Understanding abdominal aortic aneurysm progression through three-dimensional microstructure imaging /." May be available electronically:, 2007. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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36

Troxler, M., Khalid M. Naseem, and Shervanthi Homer-Vanniasinkam. "Increased nitrotyrosine production in patients undergoing abdominal aortic aneurysm repair." Wiley, 2004. http://hdl.handle.net/10454/4094.

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no<br>Vascular inflammation is implicated in the pathogenesis of atherosclerosis and abdominal aortic aneurysm (AAA), and is thought to involve reactive species such as the nitric oxide-derived oxidant peroxynitrite. In the present study nitrotyrosine was measured as a stable marker of peroxynitrite production in vivo. Perioperative blood samples were obtained from patients undergoing elective open or endovascular repair of an AAA and from patients with intermittent claudication, smoking aged-matched controls, non-smoking aged-matched controls and non-smoking young healthy controls. Plasma nit
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Sidloff, David Adam. "The epidemiology of abdominal aortic aneurysm and natural history of type II endoleak after endovascular aneurysm repair." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/33067.

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Abdominal aortic aneurysm is an important cause of death globally, however, its impact is less today than two decades ago due to a decline in AAA mortality. Within the same timeframe changes have occurred to the way that AAA may be treated, for example an increasing use of endovascular surgical techniques. Type II endoleak is one of the most common complication of endovascular aneurysm repair. The sequela of having a type II endoleak is however unknown. My objectives within this thesis were to analyse causes of the decline in aneurysm mortality being seen in many developed countries using data
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38

Solanich, Valldaura Teresa. "Síndrome compartimental abdominal en aneurismas de aorta abdominal rotos." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/665385.

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Introducción: Los aneurismas de aorta abdominal rotos (AAAR) presentan una alta tasa de mortalidad, incluso aquellos pacientes que sobreviven a la cirugía (32 al 80%1-4). El fallo de varios órganos en el postoperatorio inmediato supone una causa frecuente de muerte. El síndrome compartimental abdominal (SCA) se presenta en un 30-53%, independientemente de la técnica terapéutica realizada (cirugía abierta o endovascular), pudiendo comportar un fallo multiorgánico, con una mortalidad de más del 70%(3). El SCA es un factor predictor de mortalidad en los AAAR, su prevención, detección y tratamien
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39

Thompson, Andrew. "The aetiology behind AAA disease formation and progression." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/17595/.

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AAA disease remains a common and life threatening condition, predominantly affecting men of retirement age. Whilst clinical studies have done much to predict the course of this disease, understanding the pathogenesis has been complicated by both a multi-factorial aetiology as well as several poorly defined stages to the disease (formation, growth and rupture). Evidence points to a considerable inheritable component to this condition, but as yet, associations with identified genetic variants are few and weak. This thesis describes the current understanding of the molecular mechanisms behind AAA
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40

Sun, Zhonghua. "CT virtual intravascular endoscopy in aortic stent grafting." Thesis, University of Ulster, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248607.

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41

Maroney, Roy Thomas. "Missed opportunities for the detection of abdominal aortic aneurysms : a retrospective study of eighteen patients presenting with a ruptured or acute symptomatic abdominal aortic aneurysm." Master's thesis, University of Cape Town, 1997. http://hdl.handle.net/11427/25566.

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A ruptured abdominal aortic aneurysm (AAA) has a mortality of 80 percent. The majority of these cases present as medical emergencies, with 50 percent dying before they reach hospital. Twenty percent are not operated on because of an incorrect diagnosis and of the surviving 30 percent, there will be a peri-operative mortality of 40 percent. Thus only 20 percent of patients survive this condition. It is important to state that the long-term survival reported for patients undergoing AAA surgery approximates that of age-matched populations. This is in contrast to patients undergoing a coronary byp
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42

Alves, Lais Missae Murakami Domingues Estraiotto. "Estudo da expressão sérica do microRNA-1281, proteína C reativa e avaliação da função renal em indivíduos com aneurisma de aorta abdominal antes e após tratamento endovascular." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17137/tde-28052018-160605/.

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Introdução: O aneurisma de aorta abdominal (AAA) é uma doença prevalente e silenciosa também relacionada com a atividade inflamatória. Atualmente, a abordagem endovascular tem sido utilizada como principal técnica devido à inúmeras vantagens. Porém tem uma maior taxa de reintervenções e necessita de seguimento periódico com angiotomografias, o que aumenta custos e tem implicações como alteração da função renal além do acúmulo progressivo de radiação. Tais condições justificam a busca por possíveis biomarcadores que possam contribuir para um melhor seguimento. Objetivos: Neste estudo, buscou-se
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43

Adam, Donald John. "Coagulation, fibrinolysis and endothelial cell activation in abdominal aortic aneurysm repair." Thesis, University of Edinburgh, 2003. http://hdl.handle.net/1842/25152.

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The hypothesis of this thesis is that deranged coagulation, fibrinolysis and endothelial cell activation contribute to the thrombotic and haemorrhagic complications associated with AAA repair. In a retrospective study, 83% of 741 patients with ruptured AAA admitted to a regional vascular unit were operated upon and the operative mortality rate was 37%. Thrombotic and haemorrhagic complications including cardiac events, renal and respiratory failure, coagulopathy, lower limb ischaemia, stroke and pulmonary embolism were the major factors contributing to peri-operative mortality. Only 35% of pat
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44

Galle, Cécile. "Inflammatory and helper T lymphocyte responses in human abdominal aortic aneurysm." Doctoral thesis, Universite Libre de Bruxelles, 2006. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210815.

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Summary of the work<p>Abdominal aortic aneurysm (AAA) is a chronic degenerative disease that usually affects men over 65 years with an estimated prevalence of 5%. Aneurysm rupture represents a catastrophic event which carries a mortality rate of almost 90%. Current therapeutic options for AAAs measuring 5.5 cm in diameter or larger are based on prophylactic surgery, including conventional open reconstruction and endovascular stent-graft insertion. For patients with small asymptomatic AAAs (4.0 up to 5.5 cm in diameter), evidence from two recent large randomized controlled trials indicates no l
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45

Wilson, W. Richard W. "Molecular and clinical observations in abdominal aortic aneurysm pathogenesis and treatment." Thesis, University of Leicester, 2006. http://hdl.handle.net/2381/29521.

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The rupture of an abdominal aortic aneurysm is associated with a mortality of 60-70% and accounts for approximately 8000 deaths per year in men over 60 years of age in the United Kingdom. Aneurysm formation is clinically silent until, with increasing diameter, rupture occurs. At a cellular level, aneurysm formation is associated with an atherosclerotic or inflammatory trigger. An initial loss of elastin and smooth muscle cells from the aneurysm wall causes early aortic dilatation. Continued expansion and rupture is thought to be due to the loss of collagen mediated via either a global or local
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46

Anderson, Michael A. B. "Organ injury following ruptured abdominal aortic aneurysm is mediated by oxidants." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0028/MQ50434.pdf.

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47

Monsur, Kazi. "Cellular and molecular mechanisms in abdominal aortic aneurysm growth and rupture /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-558-5/.

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48

Wanhainen, Anders. "Abdominal Aortic Aneurysm : Experience from a Screening Study in Northern Sweden." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4459.

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49

Foulds, Sharmila. "Neutrophil activation in organ failure after thoraco-abdominal aortic aneurysm repair." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396009.

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50

Desai, Grishma Mahesh. "Automated extraction of abdominal aortic aneurysm geometries from CT scan data." Thesis, University of Hull, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441672.

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