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Paumgarten, Fiona. "The significance of the safety-net role of NTFPS in rural livelihoods, South Africa /." Thesis, Rhodes University, 2007. http://eprints.ru.ac.za/871/.
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Tételin, Stéphanie. "An analysis of wnt signalling molecules in Xenopus pronephros development." Thesis, University of Warwick, 2008. http://wrap.warwick.ac.uk/871/.
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The aim of the project was to characterise known wnt signalling molecules during the early pronephros patterning using novel and effective bioassays in Xenopus embryos. Anterior somites have been shown previously to have unique biological activity to induce pronephros formation in Xenopus embryos (Seufert et al., 1999). A molecular approach consisted of analysing the expression of canonical wnts (wnt6, wnt7b, wnt8, wnt9a and wnt9b) and the non-canonical wnts (wnt4, wnt5a, wnt11 and wnt11b) genes in isolated pronephric anlagen and pronephros from stage 12.5 to stage 35 and in anterior and posterior somites. This allowed the identification of potential candidate wnt genes which could act as pronephric inducers. Their potential to induce pronephros was tested in vitro using the Holtfreter sandwich culture pronephrogenesis assay, which consists of unspecified intermediate mesoderm cultured inside two animal caps over-expressing the wnt molecule of interest. Results suggest that the canonical wnt molecules (wnt6 and wnt8) are capable of modifying the intermediate mesoderm leading to formation of somite and neural tissue that in turn, can secondarily induce pronephric tubule formation. By contrast, signals of the non-canonical wnt11 and wnt11b are sufficient to directly specify the intermediate mesoderm to become kidney. In vivo, the role of the canonical wnt6, non-canonical wnt11b and the closely related wnt11 gene was investigated by gain and loss-of-function experiments. Results suggest that mis-expression of these genes disturb the normal formation of the pronephric tubules and suggest that both canonical and non-canonical wnt molecules are required for formation of functional pronephros. This thesis also reports the identification of the novel Xlwnt9a and Xlwnt9b genes, their temporal and spatial expression in both X. laevis and X. tropicalis embryos and dissected adult organs and analyses the effects of Xtwnt9b mis-expression on X. laevis pronephros development.
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Webster, Lisa Amalia Denza. "Understanding episodic memory in animals and humans : a methodological approach." Thesis, Durham University, 2011. http://etheses.dur.ac.uk/871/.
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This thesis sought to explore two different methodological approaches to episodic memory, namely episodic memory as demonstrated in humans and episodic-like memory as demonstrated in animals. The results of Chapter 2 were successful in demonstrating episodic-like memory in the rat using recollection alone, despite the fact that performance in this study was significantly poorer compared to the original (Eacott, Easton, & Zinkivskay, 2005). Subsequent experiments within this chapter highlighted potential methodological issues (e.g. interference of odour cues, stability of performance over lengthy testing periods) that impact on such spontaneous tasks. Chapter 3 investigated the effect of bilateral lesions to the hippocampus on episodic-like memory. The results of Chapter 3 were not in agreement with previous findings as none of the three groups (Sham Group/Partial Hippocampal Group/Hippocampal Group) showed evidence of episodic-like memory. In depth analyses of the three groups lead the author to the conclusion that this was not due to an ineffective task but due to extraneous factors impacting upon the performance of the animals. Analyses of D2 scores and raw exploration times in both phases of the experiment also highlighted the importance of D2 scores in determining object familiarity. Chapter 4 further investigated the effect of bilateral lesions to the hippocampus on episodic-like memory in animals using an Open Field arena. The addition of landmarks to the testing room resulted in the Sham group successfully demonstrating episodic-like memory whilst the Hippocampal lesion group remained at chance levels. As there was no significant difference between the two groups it was not possible to conclude that this was as a result of the lesions to the hippocampus. The control task showed neither group demonstrating memory for the more simple ‘what-where’ task, therefore it was concluded that a problem with the methodology still remained. Subsequent experiments within this chapter investigated cleaning methodology, the stability of performance over time, and the effect of task change on performance. The clear variability in the data over lengthy testing periods emphasised the sensitivity of such tasks. Chapter 5 aimed to investigate whether applying comparable ‘What-Where-When’ and ‘What-Where-Which’ tasks to human investigations of episodic memory would result in similar patterns of data with regard to recollection and familiarity. Analysis of the results revealed the use of other strategies to solve the episodic ‘What-Where-When’ questions. Subsequent experiments within this chapter aimed to confirm the use of strength of memory trace as a strategy for solving these episodic questions. Results from the final experiment suggested that other strategies were also being employed in addition to strength of memory trace. Conclusions were drawn regarding the individual components of episodic memory and their susceptibility to interference from other strategies. Overall conclusions focused on the definition of episodic memory and the potential implications of alternative strategies impacting on such tasks.
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Manning, Peter. "Justice, reconciliation and memorial politics in Cambodia." Thesis, London School of Economics and Political Science (University of London), 2014. http://etheses.lse.ac.uk/871/.
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This thesis examines conflicts and congruities between memories of past political violence, and the implications these have for attempts to enable ‘justice’ and ‘reconciliation’ in Cambodia. The project takes the establishment of the Extraordinary Chambers in the Courts of Cambodia (ECCC) as a starting point that seeks to stabilise a narrow account of past political violence. The ECCC is important as a point of departure because it is the main institutional site through which Cambodia is confronting past political violence. Tasked with prosecuting crimes perpetrated by Khmer Rouge between 1975 and 1979, the ECCC promotes a restricted reading of political violence in Cambodia, attempting to silence some pasts whilst calling attention to others. At the same time, the work of the ECCC situates the past as a field of intervention that can yield particular ameliorative social and political outcomes: providing a sense of justice, establishing the truth of political violence in Cambodia, deterring the future perpetration of atrocity, and enabling reconciliation. Memory is integral to these ends as the key target of civic renewal. Based on eight months of fieldwork in 2008/9 conducted at multiple sites in Cambodia, the project critically reflects on the ECCC’s attempt to generate a unified and consensual account of political violence in Cambodia. Three key findings are evidenced. Firstly, whilst the ECCC attempts to frame and stabilise a preferred account of political violence through a judicial process that reconstructs memory through disclosure and concealment, this process itself is contested by the subjects it animates (its ‘victims’ and ‘perpetrators’). Moreover, I argue that the work of the ECCC actually catalyses multiple, often conflicted claims over what justice and reconciliation mean as socio-political strategies. The ECCC continues to generate unintended and unexpected results in the way that it platforms, recues and generates demands of the past. Secondly, the research findings evidence diverse and competing regimes of memory in Cambodia that call into question the possibilities of the ECCC in reconstructing a unified, shared public memory of political violence in Cambodia, and providing a sense of justice and reconciliation on that basis. These are frequently encountered exactly at the propagation of the ECCC preferred reading of past political violence, gesturing to the way that conflicting memory occurs – or is foregrounded – in resistance to power. Thirdly, the research findings evidence competing rationales for remembering and forgetting political violence in varied ways (for example, material priorities, tourism, and attendant commercial interests). Moreover, the thesis documents ambivalence among some Cambodians toward memorials and museums and the pasts that they call attention to. In this sense, the project shows how these ambivalences are dislocated from and eschew the moral authority of the rationales grounding the ECCC’s work (providing a sense of justice and facilitating reconciliation in the name of continued memories of political violence).
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Mancini, Giorgio. "Realizzazione del sistema di controllo motore di una vettura Formula SAE." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amslaurea.unibo.it/871/.
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Carannante, Simona <1976>. "Multiresolution spherical wavelet analysis in global seismic tomography." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2008. http://amsdottorato.unibo.it/871/.
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Every seismic event produces seismic waves which travel throughout the Earth.
Seismology is the science of interpreting measurements to derive information about the structure of the
Earth. Seismic tomography is the most powerful tool for determination of 3D structure of deep Earth's
interiors. Tomographic models obtained at the global and regional scales are an underlying tool for
determination of geodynamical state of the Earth, showing evident correlation with other geophysical and
geological characteristics. The global tomographic images of the Earth can be written as a linear
combinations of basis functions from a specifically chosen set, defining the model parameterization. A
number of different parameterizations are commonly seen in literature: seismic velocities in the Earth
have been expressed, for example, as combinations of spherical harmonics or by means of the simpler
characteristic functions of discrete cells.
With this work we are interested to focus our attention on this aspect, evaluating a new type of
parameterization, performed by means of wavelet functions. It is known from the classical Fourier theory
that a signal can be expressed as the sum of a, possibly infinite, series of sines and cosines. This sum is
often referred as a Fourier expansion. The big disadvantage of a Fourier expansion is that it has only
frequency resolution and no time resolution.
The Wavelet Analysis (or Wavelet Transform) is probably the most recent solution to overcome the
shortcomings of Fourier analysis. The fundamental idea behind this innovative analysis is to study signal
according to scale. Wavelets, in fact, are mathematical functions that cut up data into different frequency
components, and then study each component with resolution matched to its scale, so they are especially
useful in the analysis of non stationary process that contains multi-scale features, discontinuities and
sharp strike. Wavelets are essentially used in two ways when they are applied in geophysical process or
signals studies: 1) as a basis for representation or characterization of process; 2) as an integration kernel
for analysis to extract information about the process.
These two types of applications of wavelets in geophysical field, are object of study of this work.
At the beginning we use the wavelets as basis to represent and resolve the Tomographic Inverse
Problem. After a briefly introduction to seismic tomography theory, we assess the power of wavelet
analysis in the representation of two different type of synthetic models; then we apply it to real data,
obtaining surface wave phase velocity maps and evaluating its abilities by means of comparison with an
other type of parametrization (i.e., block parametrization).
For the second type of wavelet application we analyze the ability of Continuous Wavelet Transform
in the spectral analysis, starting again with some synthetic tests to evaluate its sensibility and capability
and then apply the same analysis to real data to obtain Local Correlation Maps between different model
at same depth or between different profiles of the same model.
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Grant, Linda. "'Turning others' leaves' : imitatio and intertextuality in sixteenth-century English receptions of classical Latin love elegy." Thesis, Birkbeck (University of London), 2014. http://bbktheses.da.ulcc.ac.uk/74/.
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This thesis situates itself within the field of classical reception, and explores the appropriation and imitation of Latin erotic elegy (Catullus, Propertius, Ovid, Sulpicia) in the love poetry of sixteenth-century England. It shows imitatio to be a dynamic, rich and sophisticated practice, one which may be productively read as both a form of intertextuality and reception, terms which capture its contingent and active nature. The readings here re-calibrate Petrarch’s canzoniere suggesting that this influential sequence of love sonnets is itself a moralised re-writing of Roman erotic elegy. By re-framing the ‘Petrarchan’ love poetry of Thomas Wyatt, Philip Sidney, John Donne and Mary Sidney as elegiac receptions, the readings here re-open these familiar texts and offer fresh interpretations of how they can be made to mean. The introduction traces the presence of Latin love elegy in the early modern period, and shows that a modern scholarly over-reliance on Petrarch and Ovid has obscured the way Renaissance love poetry is also shaped by and through its relationships to the texts of Catullus, Propertius and Sulpicia. The four chapters which follow trace these intertextual relationships in detail through readings of a small number of poems: those of Catullus and Wyatt, Propertius and Sidney, Ovid and Donne, and Sulpicia and Mary Sidney. The interventions which this project makes are two-fold: firstly it applies modern theories of reception and intertextuality to Renaissance love poetry, and refreshes the way imitatio may be read. Secondly, it re-frames ‘Petrarchan’ love poetry of sixteenth-century England and reveals it to be a complex, subtle and sometimes revisionary re-writing of Latin love elegy. By reading the multiple concerns of elegy and its sometimes problematic uses of love, gender and erotic desire into the selected English texts, this project offers fresh interpretations of both bodies of poetry, and demonstrates that Roman elegy has a vital and complex presence in the poetics of sixteenth-century England.
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Norris, Oliver William. "The Gospel text used by Sedulius in the Paschale Carmen and Paschale Opus." Thesis, King's College London (University of London), 2016. https://kclpure.kcl.ac.uk/portal/en/theses/the-gospel-text-uised-by-sedulius-in-the-paschale-carmen-and-paschale-opus(6dbfcca1-b380-476a-bf6a-186aac563a79).html.
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This study examines the Gospel citations in the Paschale Opus and the Paschale Carmen, the twin works of the 5th-century Latin poet Sedulius. To date no study had conducted a full investigation of the origin and use of Sedulius's Gospel sources in both works, composed in the middle of a crucial period in the evolution of the Latin Bible. Sedulius's biblical citations were broken up into variant sites that were analysed against the principal traditions in the Old Latin and Vulgate versions of the Gospels. The full collection of these variant sites can be found in the Appendix. The analysis of these variant readings proposes that Sedulius's Gospel citations in both works are principally Old Latin, closest among unmixed Old Latin codices to the Veronensis (VL4) in Matthew, the Corbiensis II (VL8) in Luke and the Usserianus I in John (VL14), but his citations also reveal that Sedulius made significant use of the Vulgate, especially in book two of the Paschale Opus. Sedulius's biblical text reveals his use of homilies and the importance of the liturgy on the composition of his works but his biblical citations are nearly always paralleled by an Old Latin or Vulgate manuscript witness rather than those forms found in the earliest witnesses to the liturgy. Finally, the study's findings have important consequences for our knowledge concerning the use and dissemination of what came to be known as the Vulgate version of the Gospels.
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Asciutti, Valentina. "Poetic Britannia : a census of Latin verse inscriptions." Thesis, King's College London (University of London), 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616910.
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The purpose of this research is to collect in a distinct corpus all the Latin verse inscriptions found in Roman Britain, those entirely metrical and those mixed with prose, those definitely metrical and those questionably so as well, analyse them both individually and as a block, with all the relative interconnections. The texts are also considered as evidence for a certain type of Romanisation spread in the province from the first to the fourth century AD. The aim of my research is to: - create a complete census of all the Latin verse inscriptions gathered from Roman Britain - trace the history of their discovery and map out the previous, including antiquarian, studies on them. This proves to be particularly useful for those inscriptions that experienced a tangled history and where with time some crucial details about the text and its archaeological context went missing in the accounts. - analyse the texts both from an epigraphic-historical and linguistic-philological point of view - offer fresh interpretations and supplements of the fragmentary texts - put the inscriptions in relation to their archaeological context - consider the implications for the cultural level of the province during the Roman occupation The results arc compared to those extrapolated from the metrical inscriptions found in Gallia Belgica. My investigation has clearly shown that the use of verse inscriptions in Britannia was markedly different from that in neighbouring Belgica. The comparison brings interesting conclusions and observations regarding the different approach and use of verse inscriptions in the two Roman provinces. Latin verse inscriptions represent an interesting key-study on the leve I of culture and sophistication that the Romans, together with the locals, achieved in a provincial environment. The comparative study proves the thesis that verse inscriptions do say something about the type of Romanisation of a province: the metrical texts found in Belgica are in fact quite different from those from Britannia.
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Ingleheart, J. "A Commentary on Ovid Tristia 2.1-262." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665295.
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The thesis consists of text, translation, and commentary on the first 262 lines of Tristia 2. During my doctoral studies, I have written a first draft of text, translation, and commentary on the poem in its entirety; only a section of this could be submitted for examination. This portion was selected for comment because these lines include important information about the carmen et error which avid blames for his exilic predicament, and because they encapsulate a characteristic feature of the work: engagement with contemporary affairs coupled with an interest in literary matters. There is also a brief general introduction to Tristia 2, in which there is a short account of major issues surrounding the poem; some of the material found in the parts of the commentary not submitted for examination is treated here. Stylistic comment is found in the main body of the commentary. Textual matters are discussed in the main body of the commentary. The translation is primarily intended as a tool to aid the reader's understanding of the poem. In the commentary, there is detailed line by line analysis and interpretation of aspects of the poem such as historical references, allusion, etymological play, ambiguities, and humour, as well as technical issues such as usage, grammar, and metre. In terms of historical content, the thesis pays particular attention to Ovid's engagement with the ideology and iconography of the Augustan period. The overall concern of the thesis is to consider Tristia 2 in the context of Ovid' s corpus as a whole, since it provides readings of his earlier works, and a key to understanding those that follow it.
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Ricks, Catherine. "The weight of a whole author on my shoulders : Dryden's Virgil." Thesis, University of Oxford, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665300.
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One of the few monographs on Dryden's Aeneis cites Earl Miner: 'The definitive study of Dryden's Virgil remains to be written, but it seems beyond question that it is the most important translation in the language' (Corse, 1991). The aim of this thesis is to reopen the following questions: Why did Dryden undertake it? What qualities did he bring to this venture, at what he calls his 'great Clymacterique'? What in retrospect makes this work such a significant literary landmark? The main contribution I seek to make is a fuller consideration of Dryden's Virgil as a unitary work, and virtually unique as a complete translation of Virgil by a major poet. The Introduction provides contexts for my argument: a summary of current Dryden criticism , and of current Virgil scholarship. Chapter 1 considers Dryden's translation in the context of contemporary and later conceptions of Virgil in English poetry. Chapter 2 examines Dryden's trans-historical perspective and the formative role of his Lucretius (1685), and the influence (to a lesser degree) of Plutarch. Chapter 3 examines the neglected Pastorals, focusing on their tonal complexity and the quest for poetic sublimity in 'hard Iron Times'. Chapter 4 considers the Georgics, 'the best poem of the best Poet', its generic originality and contribution to the cultivation of English verse, and as an articulation of Virgil's Lucretian dimension. Finally, Chapter 5 discusses heroic ambivalence and 'tragical satyre', and Lucretian elements in Dryden's Aeneis. The Conclusion draws together unifying features of the work, the 'secret Beauties' of Dryden's translation that vindicate his aim to bear the 'weight of the whole Author' and show his responsiveness to 'Virgil's Design'. I argue that it is through this translation that Dryden finds his English voice.
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Taraskin, Paulina. "Reading Horace's lyric : a tenth-century annotated manuscript in the British Library (Harley 2724)." Thesis, King's College London (University of London), 2013. https://kclpure.kcl.ac.uk/portal/en/theses/reading-horaces-lyric(112565d8-2b86-4e31-ab6a-387757ed50a9).html.
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The thesis presents a detailed analysis of scholia found in the late tenth- or early eleventh-century Bavarian Horace manuscript, British Library Harley 2724. I append a full transcript of scholia found in the lyric part of this manuscript. The Harley annotations are distinguished by extensive verbatim use of texts and commentaries, particularly Orosius, Eutropius, Paul the Deacon, Dares, Dictys, Solinus, Cicero’s De Senectute, Isidore’s Etymologiae, Macrobius’ In Somnium, Servius, Remigius’ commentary on Martianus Capella, scholia on Statius’ Thebaid, Bede’s commentary on the Acts of the Apostles, and other sources. One the basis of the examined evidence, I suggest that the annotations form a unified body. The annotator(s) favours extensive narrative; the choice of material is not restrained by relevance to Horatian lemmata; there is a tendency to collect and compile material from multiple sources; the approach is encyclopedic, not rhetorical or stylistic. Harley 2724 is annotated in multiple hands, but these cannot be connected with the use of specific sources. It is clear from manuscript and textual evidence that the original compilation predates Harley 2724, yet seems close to Harley in place and date. In addition to the distinctive annotations described above, Harley 2724 also includes some Horace scholia, such as we find in other Horace manuscripts. Results of a comparative study of Harley 2724 and Horace manuscripts of the Vatican and the Bavarian State Libraries are presented in Chapter 1 and the Transcription. Only a small proportion of medieval Horace scholia have been scrupulously studied or edited in their entirety. The most extensive study of the medieval reading of Horace, undertaken by Friis-Jensen, focuses on popularly copied ’school-room’ commentaries, which apparently emerged in the twelfth century.
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Foster, Frances. "Reading Servius in context and reception." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/reading-servius-in-context-and-reception(560dc6b2-e7d4-435b-ab6e-ccd1870959ac).html.
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The earliest Virgilian manuscripts are from the fourth century, so all we have are multiple receptions of Virgil. Virgil’s most famous commentator, Servius, lived at the time when Roman culture was being Christianised and when the greatness of Rome projected in Virgil was in flux. I focus on the reception of Virgil through Servius in this context, concluding with later adaptations in mediaeval Christian England. I identify different layers of reception. First, Servius s commentary on Virgil, in the context of his contemporaries, Claudian and Augustine. The former uses Virgil to support the greatness of Rome, the latter uses Virgil to give cultural status to his Christian interpretation. However, all three present a construction of Rome either as the great city of the past, the present or the future. Secondly, I identify persona as a layer of reception in which Servius and Virgil appear as personae constructed as characters in literary texts. Thirdly, I show how the material text can be seen as another layer of reception: whilst Virgil’s text is presented in a relatively stable format, Servius s Commentary changes with each instantiation. I analyse two Christian receptions of the physical text: Proba’s reception of Virgil, and Isidores reception of Servius. The former presents Jesus as a classical epic hero, the latter fixes words and meanings. Finally, I move to mediaeval England, and a less explicit reception of Virgil and Servius in Lydgate and Maydiston. Royal entry poems and the Fall of Princes define rulership authorised by references to the past. They re-imagine cities and rulers by projecting an imagined Roman model onto the mediaeval world. Servius can be seen as an outstanding example of why reception studies should also consider the teacher and the educator when discussing reception of Virgil in the fourth century and beyond.
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Brooks, Sarah Louise. "A commentary on Ovid, Ars Amatoria 2, 1-294." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/a-commentary-on-ovid-ars-amatoria-2-1294(fd7472e4-5366-4fb4-b72a-1037f713ae6f).html.
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This thesis (‘A commentary on Ovid Ars Amatoria 2, 1-294’) is submitted to The University of Manchester for the Degree of Doctor of Philosophy. It examines the methods through which Ovid presents internal unity and structure to the poem: through the use of the progress metaphor, and a sense of narrative progression. It also examines the generic positioning of the Ars within Ovid’s wider oeuvre, with special reference to the Amores and Heroides. It treats the poet’s use of mythological exempla, and how these are used as models (whether positive or negative) for the lover. This provides rich intertextuality with Ovid’s elegiac predecessors. As well as mythological figures, Ovid uses the models of the kolax (‘Flatterer’) and of the canvassing electioneer as a means of reconciling the lover’s traditional role as ‘slave of love’ with that of a free Roman male. These themes are exposed and analysed through a systematic, line-by-line commentary on the first 294 lines of Ars 2.
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Hulls, J. M. "The role of kingship in Statius' Thebaid." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1446011/.
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This thesis analyses Statius' Thebaid and the relationship it creates with VirgiVs Aeneid and the emperor Domitian. The poem constructs itself as a competing source of authority, both poetic and ideological. The poem aims to supersede Virgil's masterpiece as a poetic authority whilst providing Domitian with imperial, and in particular, regal ideology. The thesis examines three key qualities, virtus pietas and dementia in this regard, showing the manner in which Virgilian and Augustan interpretations are undermined and new understandings of these ideas are provided for Domitian's principate. The thesis then examines the role tyranny and tyrannical behaviour plays in the poem. The Thebaid portrays tyranny in unusual ways and promotes surprising responses to tyrannical rule. Throughout the poem, Statius is working to provide his audience, especially Domitian, with an educational framework for understanding models of kingship Domitian should learn from the negative examples the Thebaid provides. Statius uses the Thebaid as a step in a poetic oeuvre whose design is nothing less than to make the poet himself powerful by becoming the poetic voice on which his emperor depends.
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Manasseh, James. "A commentary on Statius' 'Thebaid' 1.1-45." Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/11354.
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This dissertation discusses the proem of Statius' Thebaid (1.1-45) and the analysis of the text is split between an introduction, three extended chapters and a lemmatized commentary. Statius' acknowledgements of his literary debts, in particular Virgil, encourages, if not demands, an intertextual reading of his poetry. As such, my first chapter, Literary Models, looks at how Statius engages with his epic models, namely Homer, Virgil, Lucan and Ovid, but also how he draws upon the rich literary Theban tradition. Like all Roman poets, Statius is highly self-conscious of his craft, and draws upon Hellenistic and lyric models to enrich his epic and define himself as an exemplary poet. I will argue that the proem offers a useful lens for analysing the Thebaid and introduces his epic in exemplary fashion, in the sense that he draws attention to the concept of opening his epic with the use of traditional tropes (namely, the invocation of inspiring force; a recusatio; an imperial encomium and a synopsis of the poem's narrative). Considering the importance of origins in the Thebaid, and the inability to escape them, I consider the proem, in this sense, the origin of the poem itself insofar as elements of it are constantly ‘remembered' and reiterated throughout the poem. The central feature of the proem is the encomium to Domitian, in which Statius advises Domitian to realize his own limits and hence retain order of the world he rules over, articulating contemporary concerns about succession and empire. Statius, in a similar manner, expresses intent to impose limits upon his own poem, which prompted me to write the chapter entitled Restraint. The third chapter, Characterisation, draws upon the discussions in Literary Models and Restraint in an analysis of the heroes introduced at 1.41-45.
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Michalopoulos, Charilaos. "Ovid's Heroides 4 and 8 : a commentary with introduction." Thesis, University of Leeds, 2006. http://etheses.whiterose.ac.uk/21143/.
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Ovid's Heroides in the form they have come down to us are a diverse group comprising fourteen verse letters supposedly addressed by heroines of Greek mythology to their absent loved ones (Her. 1-14), one further similar letter by the Greek poet Sappho (Her. 15), and the so-called "double letters" (Her. 16-21), which consist of three pairs of letters exchanged between famous couples of myth and literature. Despite the recent revival in the study of this Ovidian work, this thesis is the first full-length comprehensive commentary on Phaedra's letter to Hippolytus (Her. 4) and Hermione's letter to Orestes (Her. 8) since 1898. In the main commentary my investigation treats issues of language, style, versification and structure in the light of possible intertextual exchanges with prior works of Greek and Roman literature (esp. Greek epic, Euripidean tragedy and Roman elegy). A wide range of literary, inscriptional and archaeological material is used to illuminate and contextualize this many-sided poetry. The introduction concentrates primarily on issues of characterization mainly from a post-feminist and intertextual perspective with emphasis on the representation of (fe)male voice and desire, and the mechanics of the generic assimilation of prior literary material to the elegiac context. In addition, the introduction also provides a detailed examination of the (mis)application of mythological exempla in terms of rhetorical effectiveness and relevance to the overall structure of both letters. The aim of this explorative study, besides including a detailed stylistic and linguistic analysis, is to offer an in-depth and multi-faceted critical examination of the poetic quality of these two poems and with the help of modern, up-to-date literary theories on genre, gender and writing to contribute further to the critical reassessment of the Heroides as a whole.
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Díaz, Mataix Llorenç. "Modulació dels nuclis aminèrgics del mesèncefal pels receptors 5-HT1A i 5-HT2A corticals. Implicació dels antipsicòtics." Doctoral thesis, Universitat de Barcelona, 2006. http://hdl.handle.net/10803/871.
Full textAbstract:
L'esquizofrènia és una malaltia cerebral crònica, greu i incapacitant que afecta l'1% de la població i que s'expressa en forma de funcions mentals anormals i alteracions en el comportament. Només amb l'aparició dels primer fàrmacs antipsicòtics va millorar sensiblement la situació d'aquests malalts. Els antipsicòtics clàssics presenten efectes secundaris greus, mentre que els antipsicòtics atípics amb una eficàcia terapèutica igual o superior que els clàssics no indueixen aquest efecte adversos.Els fàrmacs antipsicòtics atípics tenen afinitat per multitud de receptors, entre ells destaquen els receptors de serotonina 5-HT2A i 5-HT1A. Aquest receptors s'expressen de forma molt abundant a les neurones piramidals i GABAérgiques de l'escorça prefrontal medial (EPFm) que és una àrea del cervell implicada en processos cognitius superiors com el llenguatge, la intel·ligència o la memòria de treball i que s'ha demostrat que presenta alteracions anatòmiques, metabòliques i funcionals en els malalts esquizofrènics. L'escorça prefrontal medial està interconnectada amb multitud d'altres àrees corticals i subcorticals, en particular destaca l'interès de les connexions recíproques de l'escorça prefrontal medial amb els nuclis aminèrgics del mesencèfal (àrea tegmental ventral i nuclis del rafe) ja que segons les hipòtesis sobre l'etiopatogènia de l'esquizofrènia aquest nuclis estarien implicats en el desenvolupament o en el tractament de la malaltia.
L'objecte d'aquesta tesi es esbrinar el paper dels receptors 5-HT1A i 5HT2A presents a l'escorça prefrontal medial en la regulació de l'activitat de les neurones serotoninèrgiques i dopaminèrgiques, així com estudiar l'efecte dels antipsicòtics en aquestes mateixes vies.
Per dur a terme el treball s'han utilitzat tècniques in vivo com l'electrofisiologia extracel·lular, en la qual podem mesurar l'activitat elèctrica després de l'administració local o sistèmica de fàrmacs, d'una neurona de la que podem caracteritzar el fenotip i la microdiàlisi intracerebral que ens permet mesurar la concentració de neurotransmissor alliberat a les sinàpsis de la zona del cervell a estudiar.
Les conclusions d'aquesta tesi son:
1. L'estimulació dels receptors 5-HT2A incrementa l'activitat de les neurones piramidals de l'EPFm activant així el circuit EPFm-DR i per tant incrementant l'alliberament de 5-HT a l'escorça. La deshinibició del tàlem indueix el mateix efecte en l'activitat piramidal i en l'alliberament de 5-HT. En contra de treballs previs aquest efectes no semblen estar mitjançats per receptors 5-HT2A de terminals talàmics ja que la lesió del tàlem no els impedeix.
2. L'increment en l'alliberació de 5-HT induït per l'activació dels receptors 5-HT2A corticals involucra a la transmissió glutamatèrgica mitjançada per receptors AMPA del glutamat, aquest fenomen es dona igual en rata i en ratolí, la qual cosa permet el treball en models murins que no existeixen en rata.
3. L'activació dels receptors 5-HT2A corticals incrementa l'activitat de les neurones dopaminèrgiques de l'ATV i l'alliberament cortical i a ATV de DA de forma paral·lela a l'increment induït a les neurones piramidals del'EPFm, posant de manifest un control del sistema mesocortical pels receptors 5-HT2A corticals.
4. Igualment existeix un control del sistema mesocortical pels receptors 5-HT1A corticals ja que l'activació dels receptors 5-HT1A de l'EPFm també incrementa l'activitat de les neurones dopaminèrgiques de l'ATV i l'alliberament cortical i a ATV de DA de forma paral·lela a l'increment induït a les neurones piramidals de l'EPFm que projecten a l'ATV. En aquest efecte semblen estar implicades les interneurones GABAèrgiques de l'EPFm.
5. Els fàrmacs antipsicòtics reverteixen l'efecte excitador sobre el sistema 5-HT produït pel DOI mentre que els antipsicòtics atípics incrementen l'activitat del sistema dopaminèrgic mesocortical per un mecanisme que sembla implicar els receptors 5-HT1A de les interneurones GABAèrgiques del'EPFm. Aquests efectes poden estar jugant un paper clau en el mecanisme terapèutic pels quals els antipsicòtics atípics milloren l'esquizofrènia sense produir efectes adversos extrapiramidals.
THESIS SUMMARY:
The atypical antipsychotic drugs have affinity for crowd of receptors; among them highlight the receptors of serotonin 5-HT2A and 5-HT1A. These receptors are expressed in very abundant way in pyramidal and GABAergic neurons of medial prefrontal cortex that it is an area of the brain that is implicated in superior cognitive processes and it is demonstrated that has anatomic, metabolic and functional alterations in the schizophrenic patients. Medial prefrontal cortex is interconnected with the aminergic nuclei of the mesencephalon (nuclei of the raphe and ventral tegmental area) and according to the hypotheses about the physiopathology of schizophrenia this nuclei would be implied in the development or the treatment of the illness.
The objective of this thesis is to study the role of the 5-HT1A and 5-HT2A receptors present in medial prefrontal cortex in the regulation of the activity of the serotoninergic and dopaminergic neurons, as well as to study the effect of the antipsychotic drugs in these same ways.
To carry out this work, we have used two different techniques in vivo: extracellular electrophysiological recordings and intracerebral microdialysis.
The most important conclusions of this study are:
As much the activation of the cortical 5-HT2A as of the 5-HT1A receptors increase the activity of the dopaminergic neurons from ventral tegmental area and the cortical release in medial prefrontal cortex and in ventral tegmental area of dopamine neurons in according to the increase induced on the cortical pyramidal neurons showing a control of the mesocortical system for these cortical receptors.
The atypical antipsychotic drugs increase the activity of the dopaminergic mesocortical system for a mechanism that seems to imply the 5-HT1A receptors of the cortical GABAèrgic interneurons. These effects can be playing a nail role in the therapeutic mechanism for which the atypical antipsychotic drugs improve schizophrenia without producing extrapyramidal adverse effects.
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Smith, Alexis Michael Sheridan. "Searching for transiting extra-solar planets at optical and radio wavelengths." Thesis, St Andrews, 2009. http://hdl.handle.net/10023/871.
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Toews, Leslie Marilyn. "The Development of a Monolithic Shape Memory Alloy Actuator." Thesis, University of Waterloo, 2004. http://hdl.handle.net/10012/871.
Full textAbstract:
Shape memory alloys (SMAs) provide exciting opportunities for miniature actuation systems. As SMA actuators are scaled down in size, cooling increases and bandwidth, improves. However, the inclusion of a bias element with which to cycle the SMA actuator becomes difficult at very small scales. One technique used to avoid the necessity of having to include a separate bias element is the use of local annealing to fabricate a monolithic device out of nickel titanium (NiTi). The actuator geometry is machined out of a single piece of non-annealed NiTi. After locally annealing a portion of the complete device, that section exhibits the shape memory effect while the remainder acts as structural support and provides the bias force required for cycling. This work proposes one such locally-annealed monolithic SMA actuator for future incorporation in a device that navigates the digestive tract. After detailing the derivation of lumped electro-mechanical models for the actuator, a description of the prototyping procedure, including fabrication and local annealing of the actuator, is provided. This thesis presents the experimental prototype actuator behaviour and compares it with simulations generated using the developed models.
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Gall, Alecia. "Marital and Personal-Life Satisfaction Among Married, Female Graduate Students: A Qualitative Analysis of Value Conflicts." TopSCHOLAR®, 1996. http://digitalcommons.wku.edu/theses/871.
Full textAbstract:
Fifteen married, female graduate students enrolled full-time during the fall of 1994 were interviewed and audio-tape recorded, guaranteed confidentiality, and assigned pseudonyms. Questions covered the topics of values, experiences in graduate school and marriage, the impact of children, pressures, conflicts, support systems, and coping strategies. I obtained a listing of all married, female graduate students enrolled at a regional state university located in the south central United States during the fall semester of 1994. From this list I identified and contacted those fulltime students who had taken no more than a five-year break between degrees and were under the age of thirty. Other respondents were acquired through a snowball technique. Respondents ranged in age from 22 to 29. All respondents were taking at least nine credit hours (a minimum for full-time students) when interviewed, and the majors varied. Only one respondent had been divorced and now re-married. Four respondents had children living with them; all children were under the age of three. The amount of time married varied from seven months to six years. It was expected that if one suffers as a result of value conflicts associated with simultaneously performing the roles of wife and graduate student, she will express less satisfaction with or perceive poorer performance with that role. A synthesis of Homans' exchange theory and symbolic interactionism provided the theoretical foundation from which the interviews were analyzed based on the symbolically defined cost/reward, give/take situation of the married, female graduate student. The women interviewed maintained that although pursuing a graduate degree and striving to be a good wife (and in some cases mother) was a physically and emotionally stressful endeavor, the ultimate rewards were and would ultimately be worth the costs. In an effort to cope or to minimize the costs, these women temporarily altered their value systems in order to lessen the pressures. Three maintenance strategies were discovered: "comparison," "reward redefinition," and "lowering standards." The amount and type of support husbands gave their wives, according to respondents, varied and was important to their success as graduate students. Four levels of support were found: "verbal support," "active support," "nonargumentative support," and "nonsupport." Overall, respondents reported being satisfied with their marriages, although most wives believed they were not very good wives at the present time. Respondents were less critical about graduate school as a whole and complained about the lack of challenge in specific classes and programs.
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Snyman, Sanmari. "Treatment and care of children and adolescents diagnosed with Attention deficit/Hyperactivity disorder." Thesis, Nelson Mandela Metropolitan University, 2008. http://hdl.handle.net/10948/871.
Full textAbstract:
Background: In recent years the incidence of Attention Deficit/Hyperactivity Disorder (ADHD) has increased. Objectives: The primary aim of the study was to determine the treatment of children and adolescents diagnosed with ADHD in South Africa and more specifically the Eastern Cape. Methods: The study consisted of two parts, a retrospective drug utilisation study and a questionnaire survey. The drug utilisation study was conducted on chronic medication records of a private sector medical scheme administrator and contained records from 1994 to 2006. A total of 42 250 records representing 8 274 patients and 4 001 families, were analysed. The questionnaire survey was conducted in the Eastern Cape. The questionnaires were distributed by responsible pharmacists to parents of children receiving medication for the treatment of ADHD from his/her pharmacy. Fifty one completed questionnaires were analysed. Results: The average age of patients in the drug utilisation study were 14.28 (SD = 5.50) years. Males represented 77.37 percent of patients. Ritalin® 10 mg was the most frequently prescribed methylphenidate-containing product, followed by Ritalin® LA 20 mg. The two most frequently prescribed active ingredients apart from methylphenidate were fluticasone and budesonide. The two most common comorbid conditions were allergic rhinitis and asthma. The average age of patients in the questionnaire survey was 10.26 (SD = 2.51) years. Males represented 73.58 percent of patients. A third of patients had relatives previously diagnosed with ADHD. Ritalin® 10 mg was the most frequently prescribed methylphenidate-containing product. Conclusion: ADHD is a complex life-long disorder. It does not only affect the child diagnosed with the disorder, but also has effects on the family, schooling system and peer relationship. Therefore, more studies regarding the incidence and treatment of ADHD need to be conducted in South Africa.
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Faulkner, Richard Shawn. "The school of hard knocks : combat leadership in the American expeditionary forces." Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/871.
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Cadiz-Andrion, Luisa Victoria. "Investigating stakeholder concerns in accounting for co-operative equity under international accounting standards." Thesis, University of Canterbury. Accountancy, Finance and Information Systems, 2007. http://hdl.handle.net/10092/871.
Full textAbstract:
This research examines submissions from the co-operative sector in response to the exposure of Draft Interpretation D8: Members' Shares in Co-operative Entities (D8) to analyse their responses to the classification of co-operative member shares under D8. A review of extant literature revealed that the concentration of submissions to similar documents comes from investor-owned firms in developed countries; and that there is a dearth of submissions from developing countries and alternative business models, such as co-operatives. This research sought to compare and establish the similarities and differences of responses across country and regional classifications, and across income and stakeholder groups. The study conducted both qualitative and quantitative research methods of textual analysis by employing grounded theory and content analysis. The results indicate that D8 submissions primarily come from preparers in developed countries located in Europe and Central Asia and in East Asia and the Pacific regions. However, findings also show that regardless of country, regional, or income group classification, the co-operative industry expressed common concerns and issues.
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Modise, Baiso Daphney. "Social work services for children affected by HIV/AIDS in a rural area / Baiso Daphney Modise." Thesis, North-West University, 2005. http://hdl.handle.net/10394/871.
Full textAbstract:
HIV/AIDS infections are an increasingly alarming pandemic, therefore it will remain
being a challenge and a priority. The efforts of all participating and active
stakeholders are appreciated in the fight against HIV/AIDS.
This research dissertation gives an overview of the HIVIAIDS status and impact on
the affected children around Kagisano (Ganyesa) service point. This information has
been collected in Pomfret, which is a village near Ganyesa.
The survey was undertaken with the aim to investigate social work services for
children affected by HIV/AIDS in the rural area in which Pomfret is situated.
The objectives of this study were:
To investigate the needs of children affected by HIV/AIDS in a rural village
called Pomfret through a literature study and empirical research.
To investigate the role of the social worker in providing for the needs of
children affected by HIV/AIDS in Pomfret.
These objectives were achieved by means of a study of the relevant literature and
through empirical research. The available literature on the subject was consulted to
determine whether any research has been conducted in this field and whether the
subject was researchable. The empirical research was conducted to confirm the
previous research findings. The literature study and the empirical research were vital
in formulating recommendations.
In this study the survey method was used as a systematic data gathering procedure.
Data was gathered through a self-formulated schedule. The researcher administrated
the schedules by holding personal interviews with the respondents. The research was
conducted in the Pomfret district and 50 respondents were willing to be part of the
research.
The findings of this research reflect that social workers still have much to do in order
to address the needs of children affected by HIV/AIDS in rural areas.Thesis (M.A. (MW))--North-West University, Potchefstroom Campus, 2006.
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callahan, lauren k. "Chain Reactions: Mapping the Iranian Nuclear Program from 2002 to 2009." Scholarship @ Claremont, 2014. http://scholarship.claremont.edu/cmc_theses/871.
Full textAbstract:
From the revelation of the extent of the Iranian nuclear program in 2002 through the end of President Mahmoud Ahmadinejad’s first term in 2009, the interplay between international and domestic actions came to define the progression of the nuclear program. This thesis delves into these into these interactions, examining the failures and successes of Iran’s relationships with various international entities to determine how external factors affected the evolution of Iran’s nuclear program. This thesis draws upon a scientific knowledge of nuclear technology, a theoretical view of international relations, and a historical and cultural understanding of the Arab World to analyze the political and scientific ramifications of Iran’s nuclear program and directly link international actions and domestic reactions to explain the program’s progression. This clear connection elucidates the key failings of negotiations during this era: an inability of one side to understand the other.
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Raji, Abdulganiy Olayinka. "Discrete element modelling of the deformation of bulk agricultural particulates." Thesis, University of Newcastle Upon Tyne, 1999. http://hdl.handle.net/10443/871.
Full textAbstract:
The Discrete Element Method (DEM) has been applied to numerical modelling of the bulk compression of low modulus particulates. An existing DE code for modelling the contact mechanics of high modulus particles using a linear elastic contact law was modified to incorporate non-linear viscoelastic contact, real containing walls and particle deformation. The new model was validated against experimental data from the literature and physical experiments using synthetic spherical particles, apple and rapeseed. It was then used to predict particle deformation, optimum padding thickness in a handling line and bulk compression parameters during oilseed expression. The application of DEM has previously been limited to systems of hard particles of high compressive and shear modulii with relatively low failure strain. Material interactions have therefore commonly been modelled using linear contact law. For high modulus particles, particle shape change resulting from deformation is a not a significant factor. Most agricultural particulates however deform substantially before failure and their interaction is better represented with non-linear hysteretic viscoelastic contact relationship. Deformation of geometrically shaped particles in DEM is usually treated as "virtual" deformation, which means that particles are allowed to overlap rather than deform due to contact force. Change to particle shape has not previously been possible other than in the case of particles modelled as 2-D polygons or where each particle is also modelled concurrently with an FE mesh. In this work a new approach has been developed which incorporates a non-linear deformation dependent contact damping relationship and a shape change while maintaining sufficient geometrical symmetry to allow the problem to be handled by the same DE algorithms as used for true spheres. The method was validated with available experimental results on impact behaviour of rubber and the variations with different damping coefficients were simulated for a selected fruit. A fruit handling process dependent on the impact process was then simulated to obtain data required in the design of a fruit processing line. Changes in shape of spherical synthetic rubber particles and rapeseeds under compression were predicted and validated with physical experiments. Images were taken and analysed using image processing techniques with 1: 1 scaling. The method on shape change entails a number of simplifying assumptions such as uniform stress distribution and homogeneous material properties and uniform material distribution when deformed, which are not observed in real agricultural materials and will tend to overestimate the true contact area between particles. In reality for fruits and vegetables, material redistribution is a complex process involving a combination of compaction and movement. However with the new method a better approximation of bed voidage (which standard DEM approaches underestimate) and stress were obtained in the compression of a synthetic material. This is a significant improvement on existing methods particularly with respect to stress distribution within a bulk particulate system comprising deforming elements where the size and orientation of contact surface between particles has a strong influence on the bulk modulus. The new model was used for prediction of mechanical oil expression in four oilseed beds. Similar patterns in the variation of the characteristic parameters were obtained as observed in existing experimental data. The data could not be matched exactly as the quantity and arrangement of seeds in the initial seedbeds were not the same as those used in the experimental work. However the DE model gave approximate oil point data for seedbeds with the same physical properties and initial conditions as in the experiment. This suggests that the new model may be a useful tool in the study of mechanical seed-oil expression and other agricultural particulate compression processes.
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White, John Edward. "An examination of the antecedents to small and medium enterprise co-operation, and their effect on network propensity and behaviour." Thesis, University of Plymouth, 1999. http://hdl.handle.net/10026.1/871.
Full textAbstract:
Business co-operation in the small firm sector has in recent years been the beneficiary of both considerable academic debate and public sector funding for its facilitation. This thesis reviews the pertinent literature in the fields of business co-operation, trust, commitment and personality psychology. The limitations of existing networking - co-operation SME research are identified, and in particular the dearth of empirical based research. Where such research exists, no attempt is made to isolate variables which might determine whether individuals are likely to co-operate with others, and / or the likely success of their co-operative activities. As a means of addressing these perceived flaws in the literature the potential antecedent role of owner-manager's personality, business related group affiliation, and owner-manager's and firm's demographics are examined in relation to their propensity to co-operate with others. A polymorphous definition of SME sector co-operation is adopted in which it is possible for actors to co-operate with varying parties and in a number of capacities. Extensive use is made of univariate chi-square and multivariate logistic regression techniques, with a logistic regression model ultimately being extended for each of the types of co-operation identified. The second phase of the empirical research conducted is focused upon the individual business network. Potential antecedents to small firm network success are examined at the aggregate level, and recommendations offered which network actors and facilitators can utilise as a means of heightening the likelihood of success within their own groups. The thesis closes with a re-examination of the hypothesis, drawing of conclusions relating to them, and the identification of areas for further research.
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Peng, Shuang Jiu. "Filtration properties of water based drilling fluids." Thesis, Heriot-Watt University, 1990. http://hdl.handle.net/10399/871.
Full textAbstract:
This thesis reports an experimental and theoretical study on filtration properties of water based drilling fluids under dynamic and static conditions. The tested muds cover Freshwater/Gypsum/Lignosulphonate mud and SeawaterlKCLlPolymer mud, bariteweighted and unweighted. The effects of the solid concentration, pressure and shear rate on the filter cake characteristics and the erodability were investigated. For static filtration experiments, all tests were conducted for two hours and the spurt loss, the filter cake thickness, the ratio of wet to dry cake mass and the cumulative filtrate volume against time were measured. For dynamic filtration experiments, however, only the spurt loss and the cumulative filtrate volume against time were measured and all tests were conducted for at least 8 hours. A general filtration equation was developed based on the cake filtration theory prevailing in the chemical engineering industry and it was utilised to obtain the modified classic static filtration equation and the dynamic filtration equation. The modified classic static filtration equation was then employed to fit the static filtration experimental data and the average specific static cake resistance and the effective filter medium resistance were calculated. The dynamic filtration equation showed a substantial agreement with the dynamic filtration experimental data. Using the static filter cake properties such as the ratio of wet to dry cake mass (m), the average specific dynamic cake resistance, the effective filter medium resistance and the dynamic filter cake erodability were calculated. In the study of the relationship between the static filtration data and the dynamic filtration data, an attempt of predicting the dynamic filtration data from the static filtration experimental data was conducted. Also, an attempt was carried out to predict the static filtration data and the dynamic filtration data in a sequential process. The experimental data suggests that a substantial difference exists between the specific resistances of static and dynamic filter cakes. No apparent distinction was found, however, between spurt loss and effective filter medium resistance. The reodability of dynamically deposited mud cake for Seawater/KCL/Polymer mud was found to be three fold for Freshwater/Gypsum/Lignosulphonate.
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Villalpando, Eugenia P. "Factors influencing perceptions of teachers : the role of locus of control and academic perceptions of self." Scholarly Commons, 2015. https://scholarlycommons.pacific.edu/uop_etds/871.
Full textAbstract:
This study examined teacher-student relationships from the perspective of adolescent students. Poor relationships between students and teachers can lead to many negative outcomes, such as school failure and risky behaviors. While this relationship has been analyzed often, it is typically from the point of view of the teacher rather than the student. Individual cognitive appraisals of both efficacy and attribution impact how feedback from teachers is interpreted. Of particular interest is whether individuals attribute academic failures to external sources, such as teachers, which could impact the 5 teacher-student relationship. Determining factors that influence students' perceptions of teachers has implications for both student- and teacher-centered interventions. Data on academic self-efficacy, self-concept, locus of control, and perception of teachers was obtained from a racially diverse population of approximately 500 participants from a Catholic high school in Northern California. Path analysis was used to analyze possible causal relationships. Results indicate that both academic self-efficacy and locus of control significantly impact students' attitudes toward teachers. Locus of control was also found to partially mediate the relationship between academic self-efficacy and perceptions of teachers. Boosting academic self-efficacy will likely improve students' perceptions of their teachers. Attribution retraining is also implicated as an appropriate intervention to improve perceptions of teachers for students with low academic self-efficacy.
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Szanto, Edit. "Developing of a Copyright and Intellectual Property Policy and Online Training for a Community College." NSUWorks, 2004. http://nsuworks.nova.edu/gscis_etd/871.
Full textAbstract:
Proliferation of new technologies has greatly increased the complexity of copyright and intellectual property issues faced by higher education institutions. Colleges and universities have an obligation to effectively manage their intellectual assets and minimize institutional liability by ensuring that their faculty, staff, and students have access to informational materials that accurately describe, and promote compliance with, copyright and intellectual property laws and regulations, and are aware of their rights and responsibilities. In order to manage the growing complexity and minimize risk, many higher education institutions are adopting a two-pronged approach: developing comprehensive copyright and intellectual property policies, and providing customized, relevant and highly accessible training on copyrights. Although implementing a copyright policy does not by itself eliminate liability, implementing a well-drafted copyright policy is probably the best insurance against institutional liability, and providing ongoing copyright and intellectual property training is an effective way to reduce the risk of infringement. The policy and training developed must be customized to fit the needs, mission and culture of the institution. Furthermore, the policy and the training must be widely disseminated and accessible. The purpose of this study was to develop a comprehensive Copyright and Intellectual Property Policy and relevant online copyright training for the College of Southern Idaho, a community college in south central Idaho. The policy and online training were based on current intellectual property laws and regulations, and reflect the college's mission, needs, and culture.
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Fiorini, Jessica. "Light Suite." ScholarWorks@UNO, 2008. http://scholarworks.uno.edu/td/871.
Full textAbstract:
Light Suite is a collection of the work I produced during my enrollment in the University of New Orleans Low Residency M.F.A. program. The writing, format and length styles reflect my experimentation with my craft. It also provides insight as to what my "poetic voice" is. Light Suite attempts to entwine personal experience with engaged observation and occasional flights of fantasy. The following poems illustrate my attempt at diversifying personal, poetic style. There are travel, prose, and accidental meaning poems. There are poems that feature personal narrative and collaboration. All of my works do share one characteristic and that is the close relationship with visual representation of an oral experience. I employ white space, line breaks, line length, assonance and consonance to create works that are as close to my speaking voice as possible.
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Moraes, Ewandelina de. "Riscos de inundações e vulnerabilidade socioambiental das famílias no setor Jardim Querido em Porto Nacional – TO: a percepção dos moradores e o papel dos órgãos públicos." Universidade Federal do Tocantins, 2017. http://hdl.handle.net/11612/871.
Full textAbstract:
Este estudo foi realizado com intuito de conhecer sobre a percepção dos riscos
de inundações / enchentes com ênfase na vulnerabilidade socioambiental das
famílias residentes em parte do setor Jardim Querido e o papel dos órgãos
públicos em Porto Nacional - TO. É notório que o adensamento populacional
em áreas inadequadas à ocupação potencializa grandes distúrbios, perdas
materiais e humanas. Para tanto, foram enfocados a partir da percepção e das
respostas dos moradores de áreas que já foram impactadas e da área do
entorno sobre os riscos, as condições sociais, as percepções e as experiências
vividas. Em um primeiro momento, foram discutidos antecedentes teóricos,
englobando assuntos como o meio ambiente e a (in) justiça ambiental, a noção
de risco de inundações / enchentes, a percepção social vivida/percebida.
Quanto aos aspectos metodológicos, tratou-se de pesquisa empírica e de
campo, quando foram realizadas especialmente as coletas de dados junto às
pessoas, em suas residências e ainda em alguns órgãos públicos no município.
Assim, almeja-se que os resultados provindos deste estudo sirvam de subsídio
ao planejamento de políticas públicas, aos responsáveis pelo monitoramento e
alerta dessa área e ordenamento territorial da cidade de Porto Nacional - TO,
sempre voltadas à sustentabilidade e melhora da qualidade de vida da
população.This study was carried out with the purpose of knowing about the perception of the risks of floods with emphasis on the socioenvironmental vulnerability of families living in part of the Jardim Querido sector and the role of public agencies in Porto Nacional - TO. It is notorious that the population density in areas that are unsuitable for occupation increases great disturbances, material and human losses. To that end, they were focused on the perception and responses of the residents of areas that have already been impacted and the surrounding area on the risks, social conditions, perceptions and experiences lived. At first, theoretical background was discussed, encompassing subjects such as the environment and environmental (in) justice, the notion of risk of floods, the perceived / perceived social perception. As for the methodological aspects, it was an empirical and field research, when data collection was carried out especially with the people, in their residences and still in some organs of the municipality. Thus, it is hoped that the results from this study will serve as a subsidy for the planning of public policies, those responsible for the monitoring and alert of this area and territorial planning of the city of Porto Nacional - TO, always focused on the sustainability and improvement of the quality of life of the population.
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Melo, Raquel Alexandra dos Santos Reis de. "O impacto do Euro 2004 na percepção da Marca Portugal." Master's thesis, Instituto Superior de Economia e Gestão, 2007. http://hdl.handle.net/10400.5/871.
Full textAbstract:
Mestrado em MarketingEm pleno século XXI, os eventos estão a ter uma importância crescente ao nível Mundial, com os diversos países a competirem pela organização de Mega eventos. No ano de 1998 Portugal organizou a Expo 98 e em 2004 tivemos no nosso país um destacado mega evento mundial, o EURO 2004, bem como o Rock in Rio (evento musical). A importância económica, a escassez de estudos científicos realizados em Portugal sobre a organização de grandes eventos bem como sobre a percepção na Marca Portugal, justifica a necessidade de mais investigação nesta área. Foi desenvolvido um estudo qualitativo que permitiu aferir sobre as percepções, os sentimentos e as ideias de dois grupos distintos de indivíduos: um constituído por portugueses e outro por estrangeiros. Concluiu-se que o Euro 2004 teve um grande impacto nos portugueses, mas que ao nível dos estrangeiros inquiridos, poderia ter sido melhor aproveitado. O potencial em organizar um evento desta natureza é enorme, e o mesmo deve ser maximizado, a fim de justificar o enorme investimento necessário e de retirar o maior número de benefícios possíveis.
In the XXI century, events are having crescent role in a Global level, with many countries battling each other for the organization of Mega Events. In the year 1998 Portugal organized the Expo 98 and in 2004, we had in our country a relevant world mega event, the Euro 2004, as well the Rock in Rio (a musical event). The economic importance, the lack of scientific studies performed in Portugal about the organization of Mega events as well about the Portugal Brand perception, justifies it self the need of an investigation in this field. It was performed a qualitative study that allowed conclusion about perceptions, feelings and ideas of two distinct groups of individuals: one of Portuguese's and other of foreign people. We concluded that Euro 2004 had a great impact on portugueses, but for the foreign people, the event could have better results. The potential of organizing such an event is huge, and it should be optimized, in order to justify the enormous investments required as well to take all the benefits that is possible.
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Rolo, Ana Isabel. "Qualidade de vida em mulheres com artrite reumatóide." Master's thesis, Instituto Superior de Psicologia Aplicada, 1998. http://hdl.handle.net/10400.12/871.
Full textAbstract:
Dissertação de Mestrado em Psicopatologia e Psicologia ClínicaEste trabalho de dissertação enquadra-se na área da Psicologia da Saúde e consiste num estudo exploratório que procura investigar a Qualidade de Vida na Artrite Reumatóide. Assim, foi realizada uma extensa revisão bibliográfica, na primeira parte do trabalho, cujo conteúdo fundamenta e orienta as opções tomadas quanto à escolha do tema do trabalho de campo e respectiva metodologia. Foram descritas as mais importantes características definidoras quer da Qualidade de Vida, quer da Artrite Reumatóide. A amostra que foi objecto deste estudo foi constuída por 60 mulheres, 30 com Artrite Reumatóide e 30 sem Areite Reumatóide e sem outra doença crónica, situadas numa faixa etária entre os 25 e os 65 anos de idade. Esta, foi avaliada através da aplicação dos Questionários de Qualidade de Vida (F-84 e 36-Item Short Health Survey), pretendendo-se, deste modo, caracterizar a Qualidade de Vida em mulheres com Artrite Reumatóide, identificar variáveis que influenciam a Qualidade de Vida, e comparar a Qualidade de Vida de mulheres com Artrite Reumatóide com a de mulheres sem doença crónica. Este estudo utilizou tanto o método descritivo para descrever a Qualidade de Vida nas mulheres com Artrite Reumatóide, conhecendo e analisando as variáveis da Qualidade de Vida afectadas por esta doença, como o método comparativo de forma a comparar a Qualidade de Vida entre as mulheres com Artrite Reumatóide e mulheres sem doença crónica. Através da análise estatística dos resultados, concluímos que por um lado, a Qualidade de Vida nas mulheres com Artrite Reumatóide é média baixa, apresentando baixos valores nas variáveis como Saúde Geral, Funcionamento Físico, Papel Físico, Dor Física e Vitalidade, e que por outro lado, existem diferenças significativas entre as mulheres com Artrite Reumatóide e as mulheres sem doença crónica, no que diz respeito à Qualidade de Vida. No geral, verifica-se que avaliação da Qualidade de Vida efectuada pelas mulheres com Artrite Reumatóide é mais baixa do que a avaliação nas mulheres sem doença crónica, o que está de acordo com a hipótese geral formulada neste estudo.
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Tango, Rodrigo Casagrande. "Revisão sistemática de estudos sobre intervenções pré-operatórias de tabacologia para reduzir complicações cirúrgicas e seus custos." Master's thesis, Universidade da Beira Interior, 2010. http://hdl.handle.net/10400.6/871.
Full textAbstract:
Contexto
Quando os pacientes fumantes são submetidos a cirurgias, eles apresentam um
aumento das complicações intra-operatórias e pós-operatórias. O mecanismo
principal é a perturbação do transporte de oxigênio, causada pela exposição ao
monóxido de carbono.
Hipótese
Como algumas intervenções de tabacologia têm eficácia comprovada para reduzir o
tabagismo, essas intervenções poderiam ser empregadas como parte do preparo
pré-operatório de cirurgias eletivas, afim de reduzir as complicações cirúrgicas e
seus custos.
Objetivo
Resumir a literatura sobre complicações cirúrgicas e custos de cirurgias eletivas
após intervenções pré-operatórias de tabacologia.
Método
Revisão sistemática de estudos randomizados controlados nos quais pelo menos um
dos outcomes é a freqüência de complicações cirúrgicas ou seus custos e pelo
menos uma das intervenções é um preparo pré-operatório de tabacologia.
Resultados
As intervenções pré-operatórias de tabacologia estão associadas a uma redução
significativa da incidência de complicações de cicatrização, de complicações
infecciosas e do número total de complicações. Nota-se também uma redução dos
dias de internação em unidade de tratamento intensivo e uma redução de custos da
hospitalização.
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Mendoza, Fernández Julio César. "Producción de anticuerpos policlonales inmunoglobulina y, en huevos de gallinas inmunizadas con el veneno de la serpiente peruana Bothrops atrox (jergón)." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2010. https://hdl.handle.net/20.500.12672/871.
Full textAbstract:
El ofidismo como problemática de salud en el Perú, requiere ser atendido con estudios dirigidos a optimizar la acción de los antivenenos producidos comercialmente y además, desarrollar nuevas tecnologías destinadas a este propósito. En este aspecto, la producción de inmunoglobulina Y específica (IgY) de origen aviar es una alternativa frente a los antivenenos equinos, y es el tema en la presente investigación. Se inmunizaron gallinas ponedoras de la raza Light Brown Leghorn con 500 µg del veneno de Bothrops atrox, emulsificado con adyuvante de Freund, siguiendo la aparición de anticuerpos en suero con la técnica de inmuno difusión doble. Los anticuerpos aviares fueron aislados de la yema de huevos que contenían los niveles más altos de IgY específica, determinados previamente por la técnica de ELISA, utilizando precipitación negativa con ácido caprílico y un paso adicional de precipitación positiva con sulfato de amonio.
La masa de anticuerpos recuperados fue de 8,5 ± 1,35 mg/mL de yema habiéndose determinado en 8,3% la cantidad de IgY específica mediante cromatografía de afinidad en una columna de Sepharosa 4B-veneno. El antiveneno aviar tuvo una DE50 de 575 µL de antiveneno/mg de veneno y una potencia de 1,74 mg de veneno/mL de antiveneno aviar. Asimismo, los ensayos de reactividad cruzada mostraron que el veneno de Bothrops brazili comparte más epítopes comunes con el veneno de Bothrops atrox ya que se obtuvo un valor de 46% de reactividad cruzada en tanto que los venenos de Bothrops pictus y Bothrops barnetti tuvieron valores de 41% y 37% respectivamente; se encontró además que los venenos de Crotalus durissus (12%) y Lachesis muta (19%) tuvieron una baja reactividad cruzada con el veneno en estudio.Ofidism as a health problem in Perú requires to be attended either optimizing commercial antivenom potency and developing news technologist on this. Production of specific avian immunoglobulin Y is an alternative in relationship IgG horse antibodies, which is the main point of this research. Laying Light Brow Leghorn chickens were immunizated with 500 µg of Bothrops atrox snake venom emulsificated with Complete Freund’s adjuvant, and the IgY antibodies production was evaluated with the double immunodiffusion method. The avian antibodies were isolated from egg yolk which contained high level of specific IgY, calculated by ELISA method. Using caprylic acid negative precipitation and ammonium sulfate positive precipitation, mass antibodies recovery was 8,5 ± 1,35 mg/ml of yolk and after step on sepharosa 4B-venom affinity chromatographic, specific IgY recovery was 8,3% . The avian antivenom had a ED50: 575 µL antivenom/mg of venom and potency was 1,74 mg of venom/ml of avian antivenom. In addition, the crossing reactivity assays showed that Bothrops brazili venom share more common epitope with Bothrops atrox venom with a value of 46% of crossing reactivity whilest the Bothrops pictus and Bothrops barnetti venoms had values of 41% and 37% respectly; in contrast the venoms of Crotalus durissus (12%) and Lachesis muta (19%) had low crossing reactivity with Bothrops atrox venom.
Tesis
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Major, Jacqueline. "A solution concentration model for CIP simulation." Thesis, Cape Technikon, 2001. http://hdl.handle.net/20.500.11838/871.
Full textAbstract:
Thesis (MTech (Chemical Engineering))--Cape Technikon, Cape Town, 2001.Carbon-in-pulp technology is used extensively in the mining industry to recover metal cyanides from solution. Also this technology has found increasing application in the gold mining sector, replacing the less efficient zinc precipitation procedure. The extensive use of carbon in such processes have prompted many researchers to investigate the mechanism of metal cyanide adsorption. Not only has this provided many viable theories in the understanding of the mechanism, but has also led to an improved understanding of the effects of the various operating conditions on the ClP circuit. Also the modelling of this process has resulted in proposed rate equations of which the famous "kn" model is the most widely used in design. This is a single rate equation that could result in significant errors and hence a dual resistance model was developed. However this model is mathematically complex. Recently in an attempt to overcome the shortcomings of previous models, empirical calculations to accurately describe adsorption kinetics were developed at the Cape Technikon. These correlations were derived using batch experimental data. In this study the focus was on modeling the adsorption process on a continuous scale using a laboratory scale cascade system. This study utilized the fact that solution concentration is the main driving force for aurocyanide adsorption onto activated carbon and that carbon loading has an indirect effect on adsorption kinetics. The metal was ultimately tested against actual plant data and provided very accurate results.
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Amparo, Robin F. "Gaining Insight into Teaching: A Phenomenological Exploration of the Lived Experience of the Teachers of the Year." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/871.
Full textAbstract:
What qualities, skills, and knowledge produce quality teachers? Many stake-holders in education argue that teacher quality should be measured by student achievement. This qualitative study shows that good teachers are multi-dimensional; their effectiveness cannot be represented by students’ test scores alone.
The purpose of this phenomenological study was to gain a deeper understanding of quality in teaching by examining the lived experiences of 10 winners or finalists of the Teacher of the Year (ToY) Award. Phenomenology describes individuals’ daily experiences of phenomena, examines how these experiences are structured, and focuses analysis on the perspectives of the persons having the experience (Moustakas, 1994). This inquiry asked two questions: (a) How is teaching experienced by recognized as outstanding Teachers of the Year? and (b) How do ToYs feelings and perceptions about being good teachers provide insight, if any, about concepts such as pedagogical tact, teacher selfhood, and professional dispositions?
Ten participants formed the purposive sample; the major data collection tool was semi-structured interviews (Patton, 1990; Seidman, 2006). Sixty to 90-minute interviews were conducted with each participant. Data also included the participants’ ToY application essays. Data analysis included a three-phase process: description, reduction, interpretation.
Findings revealed that the ToYs are dedicated, hard-working individuals. They exhibit behaviors, such as working beyond the school day, engaging in lifelong learning, and assisting colleagues to improve their practice. Working as teachers is their life’s compass, guiding and wrapping them into meaningful and purposeful lives. Pedagogical tact, teacher selfhood, and professional dispositions were shown to be relevant, offering important insights into good teaching. Results indicate that for these ToYs, good teaching is experienced by getting through to students using effective and moral means; they are emotionally open, have a sense of the sacred, and they operate from a sense of intentionality. The essence of the ToYs teaching experience was their being properly engaged in their craft, embodying logical, psychological, and moral realms.
Findings challenge current teacher effectiveness process-product orthodoxy which makes a causal connection between effective teaching and student test scores, and which assumes that effective teaching arises solely from and because of the actions of the teacher.
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Ribeiro, Fabianne de Araújo. "Combined effects of chemicals and ultraviolet radiation on Daphnia magna." Master's thesis, Universidade de Aveiro, 2009. http://hdl.handle.net/10773/871.
Full textAbstract:
Mestrado em Ecologia, Biodiversidade e Gestão de EcossistemasO ambiente natural está frequentemente exposto a vários tipos de estresses, que podem ser de carácter químico, físico ou biológico, originados da actividade humana e dos processos de alteração climática. Os pesticidas são geralmente usados em práticas agrícolas para controlar doenças em vegetais e o aparecimento de pragas, e podem ser levados do solo para os sistemas aquáticos adjacentes aos locais de aplicação, onde representam um factor de stress para os organismos não-alvo. Além das exposições a químicos, o ambiente está sofrendo as consequências dos processos de alterações climáticas. Uma destas consequências é o aumento da radiação ultravioleta que chega à superfície terrestre devido à diminuição da concentração de ozono na estratosfera. O presente trabalho teve como objectivo principal elucidar alguns padrões e comportamentos biológicos relativamente a mudanças no ambiente. Para isto, com o intuito de prever as interacções entre stressores naturais e químicos, a radiação ultravioleta (RUV) e o fungicida carbendazim foram escolhidos como fontes de stressores natural e químico, respectivamente, e foram aplicados em combinação, como um exemplo das possíveis condições adversas que podem ser encontradas no ambiente. Os efeitos isolados da radiação ultravioleta em Daphnia magna foram avaliados através da utilização de uma lâmpada artificial de RUV, à qual os organismos foram expostos por um período máximo de 5 horas. Os experimentos de combinação entre RUV e carbendazim foram conduzidos com exposição constante ao químico, e uma única dose de radiação ultravioleta. Os parâmetros analisados foram sobrevivência, actividade alimentar, reservas energéticas e produção de juvenis de Daphnia magna. Para prever os efeitos das combinações, um dos modelos utilizados na análise de misturas de químicos e combinação de químicos com stressores naturais foi o utilizado. O modelo da Acção independente (AI) assume que ambos os componentes da combinação têm diferentes modos de acção, e actuam de forma independente sobre o organismo. Os efeitos são avaliados de acordo com as probabilidades de não-resposta do organismo a ambos os componentes da combinação. Há ainda outras formas de interacção entre os componentes da combinação que podem produzir um efeito mais severo (sinergismo) ou menos severo (antagonismo); os efeitos podem ser também dependentes do nível da dose aplicada ou do rácio entre os dois componentes da combinação Os resultados da exposição de Daphnia magna à radiação ultravioleta somente demonstraram um decréscimo na sobrevivência, na actividade alimentar e na produção de juvenis, com valores de dose-efeito muito próximos para todos os parâmetros, o que pode ser explicado pela diferença da sensibilidade deste organismo à radiação, de acordo com a idade em que são expostos. Os resultados das combinações entre carbendazim e RUV para o parâmetro sobrevivência foram bem ajustados ao modelo da acção independente, e não demonstraram nenhum desvio. Para a reprodução e a actividade alimentar, houve um desvio dependente do rácio entre os componentes, que demonstrou maior toxicidade para o carbendazim quando a radiação ultravioleta era o item dominante na combinação. Este estudo mostra a importância da avaliação de combinações entre químicos e stressores naturais. Neste caso, espera-se que o aumento na radiação aumente a sensibilidade dos organismos, como a Daphnia magna quando expostos a stressores químicos, como o fungicida carbendazim.
The natural environment and wildlife are often exposed to several chemicals, physical and biological stressors originated from human activities and climate changes. Pesticides are often used to control plant disease and pest in agricultural practices, and can runoff from the soil to adjacent aquatic systems, where it represents a stress factor for non-target organisms. In addition to chemical exposures, the natural environment is suffering from climate change processes. One of the consequences of that is the increasing amount of ultraviolet radiation reaching the earth’s surface due to depletion on stratospheric ozone. The present work aimed to elucidate some biological behaviors and patterns regarding changes in the environment. For that, to predict interactions between natural stressors and toxicants to Daphnia magna, the ultraviolet radiation (UVR) and the pesticide carbendazim were chosen as the source of natural and chemical stressors, respectively and were employed in combination with each other as an example of possible stress conditions that can be found worldwide in the environment. Single effects of ultraviolet radiation on Daphnia magna were assessed using an artificial UV source, by exposing the organisms to UV and visible light simultaneously, to a maximum period of 5 hours. Combined experiments of carbendazim and ultraviolet radiation were conducted with a constant chemical exposure and a single UVR dose. The parameters analyzed were survival, feeding activity, energy budget and offspring production of Daphnia magna. To predict effects of combined exposures, one of the reference models used for analysis of mixture toxicity and combination of chemical and natural stressor was applied. The Independent Action (IA) model assumes that both components of the combination have different modes of action, and act independently from each other; the effects of the combinations are based on the probabilities of nonresponse of the organism to both stressors. There are some deviations from the independent action model which can cause a more severe effect (synergism), or a less severe effect (antagonism); they might be also dose-level dependent or dose-ratio dependent. Results from single exposure of Daphnia magna to ultraviolet radiation showed a decrease in survival, feeding activity and offspring production, with similar dose-effect values, due to differences in the sensibility of the organism to UVR according to their age. Combined exposures of carbendazim and UVR for survival endpoint fitted to the IA model, showing no deviation patterns, while the response of reproduction and feeding activity were dose-ratio dependent, indicating a higher toxicity of carbendazim when ultraviolet radiation was the dominant item in the combination. This study shows the importance of evaluate the combined effects of chemicals and natural stressors. In this case, UVR increase is expected to enhance the sensitivity of organisms as D. magna when exposed to chemical stressors like the fungicide carbendazim.
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Babcock, Matthew. "Exploring and Bridging Group Divides in Climate Communications." Research Showcase @ CMU, 2017. http://repository.cmu.edu/dissertations/871.
Full textAbstract:
At the same time that additional coordination and cooperation between involved stakeholder groups is required more than ever to respond to changing environmental and socio-economic conditions, there has been an increasing trend of polarization across several important social divides (scientists/local actors, urban/rural, and political partisanship). Boundary organizations and boundary chains have been promoted as ways to help mitigate the problematic effects these divisions have on the successful communication of climate adaptation information in the water management sector. In this dissertation, I present three studies that were conducted in two regions to further explore stakeholder groups and the boundary chains that connect them. Both areas (Guanacaste, Costa Rica and Montana, USA) are historically agricultural regions experiencing ongoing environmental and socio-economic shifts. A mental models approach involving the use of interviews and surveys was used in each study area. The first two studies were conducted in Guanacaste and focused on comparing stakeholder group perceptions of their water system and hydro-climate information and on the differences in trust in forecast sources and its impact on forecast use. The results of these studies suggest that there is a distinction between the perceptions of larger stakeholder groups (e.g. government agencies or large farmers) and smaller groups (e.g. local water committees), and that this division suggests a need for boundary-type translation work. The third study was conducted in Montana with a focus on what communication strategies are used by, and what prompts engagement with, a boundary chain connecting rural agriculturalists to urban scientists. The results show that members of the network generally agree that for successful communication it is important both to not engage in ways viewed as attacks on agriculture and to make attempts to understand and respect local agricultural contexts. While there is some tension in the network, overall “buy-in” to the goal of bridging divides appears to be a common reason for engagement. In addition, organizations engage with the boundary chain for both the opportunity to connect to others and because of the need for translation between the concerns and logistics of different groups.
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Bhaduri, Samyabrata. "Regulation of CDK1 Activity during the G1/S Transition in S. cerevisiae through Specific Cyclin-Substrate Docking: A Dissertation." eScholarship@UMMS, 2014. http://escholarship.umassmed.edu/gsbs_diss/871.
Full textAbstract:
Several cell cycle events require specific forms of the cyclin-CDK complexes. It has been known for some time that cyclins not only contribute by activating the CDK but also by choosing substrates and/or specifying the location of the CDK holoenzyme. There are several examples of B-type cyclins identifying certain peptide motifs in their specific substrates through a conserved region in their structure. Such interactions were not known for the G1 class of cyclins, which are instrumental in helping the cell decide whether or not to commit to a new cell cycle, a function that is non-redundant with B-type cylins in budding yeast. In this dissertation, I have presented evidence that some G1 cyclins in budding yeast, Cln1/2, specifically identify substrates by interacting with a leucine-proline rich sequence different from the ones used by B-type cyclins. These “LP” type docking motifs determine cyclin specificity, promote phosphorylation of suboptimal CDK sites and multi-site phosphorylation of substrates both in vivo and in vitro. Subsequently, we have discovered the substrate-binding region in Cln2 and further showed that this region is highly conserved amongst a variety of fungal G1 cyclins from budding yeasts to molds and mushrooms, thus suggesting a conserved function across fungal evolution. Interestingly, this region is close to but not same as the one implicated in B-type cyclins to binding substrates. We discovered that the main effect of obliterating this interaction is to delay cell cycle entry in budding yeast, such that cells begin DNA replication and budding only at a larger than normal cell size, possibly resulting from incomplete multi-site phosphorylation of several key substrates. The docking-deficient Cln2 was also defective in promoting polarized bud morphogenesis. Quite interestingly, we found that a CDK inhibitor, Far1, could regulate the Cln2-CDK1 activity partly by inhibiting the Cln2-substrate interaction, thus demonstrating that docking interactions can be targets of regulation. Finally, by studying many fungal cyclins exogenously expressed in budding yeast, we discovered that some have the ability to make the CDK hyper-potent, which suggests that these cyclins confer special properties to the CDK. My work provides mechanistic clues for cyclinspecific events during the cell cycle, demonstrates the usefulness of synthetic strategies in problem solving and also possibly resolves long-standing uncertainties regarding functions of some cell cycle proteins.
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Yan, Dengfeng. "Investigating consumers' responses to prefixed brand names : the effects of feature perceptibility and familiarity on categorization judgment." HKBU Institutional Repository, 2007. http://repository.hkbu.edu.hk/etd_ra/871.
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Chan, Sonya. "The use of EMG for load prediction during manual lifting." Thesis, Kingston, Ont. : [s.n.], 2007. http://hdl.handle.net/1974/871.
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Marais, Inge. "Juwelierskuns en transformasie." Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/871.
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Morrison, Heather. "Directory of Open Access Journals (DOAJ)." Charleston Advisor, 2008. http://hdl.handle.net/2429/871.
Full textAbstract:
The Directory of Open Access Journals (DOAJ) is the world’s most authoritative list of scholarly, peer-reviewed, fully open access journals, and a “must” for libraries of all types. As of August 2007, DOAJ includes over 2,800 titles, over 10% of the world’s estimated 20-25,000 peer-reviewed scholarly journal titles. This is an impressive list; in terms of numbers of titles, DOAJ compares favorably with commercial journal packages. DOAJ is growing rapidly, at a rate of more than one title per calendar day. DOAJ’s highly functional and aesthetically pleasing interface features a number of search options, including a new search option for authors looking for open access or hybrid journals to publish in. DOAJ is freely available, and working towards economic sustainability through an optional membership / sponsorship program. This article examines the DOAJ membership program in some depth. Membership fees for libraries and library consortia are an incredible bargain. The membership fee for DOAJ’s 2,800 (and growing) title list is less than the average subscription cost for a single journal in any scientific discipline, and DOAJ represents significant staff time savings for libraries. The promotional benefits of DOAJ membership are important to position libraries for leadership in the internet age, and especially in the key emerging area of scholarly communications. DOAJ is a very popular service among libraries, with a strong reputation for quality; membership or sponsorship is likely to be highly beneficial to library service providers. As a free resource, DOAJ is strongly recommended for all libraries. DOAJ titles can be included in A-Z journal lists, library catalogues or websites, and subject-specific URLs can be added to subject guides or pathfinders.
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Tufenk, Tracy A. "THE EFFECT OF BEHAVIORAL SKILLS TRAINING FOR DENTAL HYGIENE STUDENTS ON TREATMENT OF SPECIAL NEEDS PATIENTS DURING DENTAL CARE PROCEDURES." OpenSIUC, 2012. https://opensiuc.lib.siu.edu/theses/871.
Full textAbstract:
This study assessed the effect of Behavioral Skills Training (instructions, modeling, rehearsal, and feedback) using a multiple baseline design to train 3 dental hygiene students to implement basic behavioral procedures (picture schedules, differential reinforcement, contingent escape, escape extinction, and least-to-most prompting) to manage and prevent challenging behavior during dental care procedures on special needs patients. The study took place in a mobile school-based dental clinic set up within 4 special schools. Training consisted of one group training session and several in-vivo training sessions. After training, participants' performance in the absence of feedback was assessed. Data show that participants performed less than 35% of steps correctly before receiving the training package and quickly reached criteria during training sessions. Results suggest that Behavioral Skills Training could be used to increase skills during one 3-hr class period, with further increases in skills to over 90% accuracy after some follow-up in-vivo practice and feedback.
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Yu, Yang. "The role of hCLCA2 and hCLCA4 in suppression of breast cancer progression." OpenSIUC, 2014. https://opensiuc.lib.siu.edu/dissertations/871.
Full textAbstract:
hCLCA2 and hCLCA4 are chloride channel regulators that are expressed in normal breast epithelial cells and frequently downregulated in breast cancers. Recent investigations revealed that these two proteins may have a role in suppressing breast cancer progression. In this thesis, I will address their role in maintaining epithelial differentiating and inhibiting cell proliferation of breast epithelial cells. The epithelial to mesenchymal transition (EMT) is a developmental program in which epithelial cells downregulate their cell-cell junctions, acquire spindle cell morphology and exhibit cellular motility. In breast cancer, EMT facilitates invasion of surrounding tissues and correlates closely with cancer metastasis and relapse. We found previously that the candidate tumor suppressor hCLCA2 is a p53-inducible proliferation-inhibitor that is frequently lost in breast cancer. We show here that another member of the CLCA gene family, hCLCA4, is expressed in mammary epithelial cells and is similarly downregulated in breast tumors and in breast cancer cell lines. Like CLCA2, the gene is stress-inducible, and ectopic expression inhibits colony formation. Transcriptional profiling studies revealed that hCLCA4 and hCLCA2 together are markers for mammary epithelial differentiation, and both are downregulated by TGF beta. Moreover, knockdown of either on in immortalized cells by shRNAs caused downregulation of epithelial marker E-cadherin, while mesenchymal markers N-cadherin, vimentin, and fibronectin were upregulated, indicating an EMT program. Double knockdown of hCLCA2 and hCLCA4 enhanced the mesenchymal profile. These findings suggest that hCLCA4 and hCLCA2 play complementary but distinct roles in epithelial differentiation. Clinically, low expression of hCLCA2 and hCLCA4 signaled lower relapse-free survival in breast cancers. Cellular senescence is a program of irreversible cell cycle arrest in response to stressors such as DNA damage, ROS, telomere erosion, or oncogene activation. It is one of the primary tumor suppression mechanisms mediated by p53 and is often disabled in cancer cells. However, the downstream signaling pathway whereby p53 induces cellular senescence remains incomplete. We reported previously that hCLCA2 was a p53 inducible gene that is downregulated with breast cancer progression. We and other group noticed that hCLCA2 was induced in parallel with several types of senescence. Lentiviral transduction of CLCA2 into MCF7 cells inhibited cell proliferation and cells showed senescence phenotype. To investigate the mechanism biochemically, we used pAd-Easy to express hCLCA2 in the model breast cancer cell line CA1d. A protein expression profile of these cells over a 6 day period revealed induction of p21, p53, and the DNA damage-response pathway. To test whether hCLCA2 is required for the cellular senescence process, hCLCA2 was knocked down in HMLE. The knockdown cells (KD) and negative control were treated with a low concentration of doxorubicin, and cell proliferation was measured. The KD cells were more resistant to growth inhibition by doxorubicin. Moreover, a time course experiment showed that induction of SA beta-galactosidase, DNA damage response, and lysosomal markers IFI30 and CTSS was delayed in the knockdown cells. These results suggest that hCLCA2 plays an important role in DNA damage response and the senescence program.
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Patel, Sonali Subhashchandra. "Non-Syndromic atrioventricular septal defects: a refined definition, associated risk factors, and prognostic factors for left atrioventricular valve replacement following primary repair." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/871.
Full textAbstract:
Congenital heart defects (CHDs) constitute a major proportion of clinically significant birth defects and are an important component of pediatric cardiovascular disease. Atrioventricular septal defects (AVSDs) include a range of anomalies characterized by atrial, ventricular, and atrioventricular (AV) valve defects. AVSDs commonly occur in the presence of a syndrome, most frequently Down syndrome; they also occur in isolation and are referred to as non-syndromic AVSDs (NSAVSDs). These studies were performed to evaluate for presence of an intermediate phenotype in parents and siblings of a child with a NSAVSD, risk factors associated with NSAVSDs, and prognostic risk factors for left AV valve replacement following primary repair of an AVSD.
It was shown that the mean body surface area-standardized AV septal length (AVSL) was significantly shorter in the NSAVSD parents and siblings than in parents and siblings of syndromic AVSD case and control children. Using age- and gender-adjusted body surface area-standardized AVSL, it was determined that there was evidence for two component distributions in parents and siblings of NSAVSD children, suggesting the presence of an intermediate. Broadening the definition of AVSD to include those with a shortened AVSL may increase the power of genetic association and mapping studies to identify susceptibility genes.
Risk factors associated with NSAVSD were examined using the 1997-2005 National Birth Defects Prevention Study database. Mothers who actively smoked or were exposed to passive smoke anytime from one month prior to pregnancy through the end of the first trimester were more likely to have an infant with a NSAVSD. There was a suggestive association between AVSDs and use of antibacterial, antifungal, and antiviral medications. Additional investigations are warranted to investigate associations with specific medications as well as to uncover possible gene-environment interaction effects that may modify these risks in order to develop improved primary prevention strategies.
Using the Pediatric Cardiac Care Consortium database, factors associated with time to first reoperation and time to replacement following primary AVSD repair were evaluated. Type of AVSD repair, closure of the mitral valve cleft, moderate to severe postoperative left AV valve regurgitation, and presence of postoperative complete heart block were associated with earlier time to reoperation after adjusting for age and weight at AVSD repair. Down syndrome and presence of postoperative mitral stenosis were associated with earlier time to replacement. Prognostic risk factors following left AV valve replacement in children who had previously undergone AVSD repair were also identified. A prosthetic valve size to body weight ratio of greater than 3 and the presence of Down syndrome were identified as predictors of in-hospital death following left AV valve replacement.
By adding to our knowledge of the AVSD familial and environmental risk factors from these studies, we will be able to (1) improve genetic counseling, (2) identify other family members for genetic testing, (3) begin to devise primary prevention strategies, and (4) improve treatment modalities. By recognizing prognostic factors which influence survival, optimal patient care can be devised which will not only improve treatment modalities, but also long-term survival.
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Lindheimer, Tomás Ernesto. "Safety Evaluation of Work Zone Practices in Utah." DigitalCommons@USU, 2010. https://digitalcommons.usu.edu/etd/871.
Full textAbstract:
Work zones present a risk to drivers and to personnel constructing the roadway. In 2005 work zones accounted for 2.5% of fatalities nationwide, 3.5% for the state of Utah. The goal of this research is to make work zones safer by quantifying the risk that they present to drivers. The approach of this research has been to review part 6 of the Manual of Uniform Traffic Control Devices (MUTCD) and compare the differences from the 2003 and 2009 editions, conduct field studies of Utah work zones, and develop a tool for measuring risk in work zones. In the 2009 MUTCD an effort is made to provide additional safety measures to disabled pedestrians. Also, guidelines are set for the use of new technology for work zones, flagger procedures, and incident management. Research was done to ascertain what several states are doing to promote safety around work zones. The states that are highlighted in this report are Arkansas, North Carolina, Illinois, Pennsylvania, New Mexico, Minnesota, and Virginia. These methods include integration of a Smart Work Zone system, late lane merge, investigation of higher quality traffic control devices, and application of other technologies to make drivers aware of work zone conditions. Discussion about the various technologies available and their effects on traffic found through research is also provided in this thesis. Research for safety and safety regulations continues.
An audit process developed at Utah State University and the Illinois Institute of Technology was used to conduct an evaluation of work zones in Utah. The audit was instrumental in evaluating the measures being used on highway and interstate roads work sites. The results and observations of this research were utilized to make standards concerning conditions of signs and delineation devices. Also observations were used to determine risk factors pertaining to a work zone. These factors were implemented in a spreadsheet that served as an analysis tool for quantification of risk in a work zone. Eleven projects in highways and arterials were audited and analyzed with the analysis tool developed. The risk scores attained from this tool range in value, and though the values may not be an exact value of the present risk, the tool still proved to be effective as an estimation device for auditors and contractors alike. The tool also proved efficient in quickly identifying the areas of concern in the work zone, and giving an estimate on the impact that improvements will have on the safety of workers and drivers. For the 11 work zones audited, the recommendations were enforcement of speed limit, improvement of signs in the work zone, and use of positive protection, among others.