Academic literature on the topic '823.7 f'

As part of the molecular recognition studies on the phytohormone indole-3-acetic acid (IAA) a series of fluorinated IAA's has been examined. The phenyl ring substitution at positions 4, 5, 6 and 7 resulted in four compounds, which were analyzed. Structure–activity correlation includes the analysis of their molecular conformations, based on the X-ray diffraction and computational chemistry results, and bioactivity determinations in the Avena coleoptile and the Pisum sativum stem straight-growth tests, lipophilicity and UV absorbance. The conformations of monofluorinated IAA's and a free hormone are defined by rotations about two bonds: one describes the relative orientation of a side chain towards the indole plane and the second the orientation of the carboxylic group. The results of X-ray structure analysis revealed the folded shape of the molecules in all compounds studied. Molecular mechanics and dynamics located the folded conformation as the local minimum, but failed to detect the planar conformation as one of the local minima, which according to ab initio results on IAA and 4-CI-IAA could also be possible. Crystal data at 295 K for 4-F-IAA and at 297 K for 5-F-IAA, and at 100 K for 6-F-IAA and 7-F-IAA using Mo Kα radiation (λ = 0.71073 Å) and Cu Kα (λ = 1.5418 Å, for 7-F-IAA), are as follows: 4-F-IAA, C10H8NO2F, Mr = 193.18, monoclinic, C2/c, a = 17.294 (5), b = 13.875 (4), c = 7.442 (4) Å, β = 103.88 (6)°, V = 1734 (1) Å3, Z = 8, Dx = 1.480 g cm−3, μ = 1.1 cm−1, F(000) = 800, R = 0.043, wR = 0.044 for 823 symmetry-independent [I ≥ 3σ(I)] reflections; 5-F-IAA, C10H8NO2F, monoclinic, P21/c, a = 19.284 (5), b = 5.083 (4), c = 9.939 (4) Å, β = 117.28 (6)°, V = 865.9 (1) Å3, Z = 4, Dx = 1.482 g cm−3, μ = 1.1 cm−1, F(000) = 400, R = 0.062, wR = 0.057 for 729 symmetry-independent [I ≥ 3σ(I)] reflections; 6-F-IAA, C10H8NO2F, monoclinic, P21/a, a = 9.360 (1), b = 5.167 (4), c = 17.751 (4) Å, β = 93.75 (1)°, V = 856.7 (8) Å3, Z = 4, Dx = 1.498 g cm−3, μ = 1.1 cm−1, F(000) = 400, R = 0.048, wR = 0.048 for 1032 symmetry-independent [I ≥ 2σ(I)] reflections; 7-F-IAA, C10H8NO2F, monoclinic, P21/a, a = 9.935 (5), b = 5.0059 (4), c = 17.610 (1) Å, β = 102.13 (1)°, V = 856.3 (1) Å3, Z = 4, Dx = 1.498 g cm−3, μ = 9.8 cm−1 (Cu Kα, F(000) = 400, R = 0.035, wR = 0.040 for 1504 symmetry-independent [I ≥ 2σ(I)] reflections.

ABSTRACT Transcriptional profiling and ontology tools were utilized to define the biological pathways of gingival epithelial cells modulated by coculture with the oral commensal Streptococcus gordonii and the opportunistic commensal Fusobacterium nucleatum. Overall, F. nucleatum and S. gordonii perturbed the gingival epithelial cell transcriptome much less significantly than the oral pathogens Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans perturbed the transcriptome, indicating that there was a greater degree of host adaptation by the commensal species (M. Handfield, J. J. Mans, G. Zheng, M. C. Lopez, S. Mao, A. Progulske-Fox, G. Narasimhan, H. V. Baker, and R. J. Lamont, Cell. Microbiol. 7:811-823, 2005). The biological pathways significantly impacted by F. nucleatum and S. gordonii included the mitogen-activated protein kinase (MAPK) and Toll-like receptor signaling pathways. Differential regulation of GADD45 and DUSP4, key components of the MAPK pathway, was confirmed at the protein level by Western blotting. Modulation of the MAPK pathway is likely to affect host cell proliferation and differentiation. In addition, both the MAPK and Toll-like receptor pathways ultimately converge on cytokine gene expression. An enzyme-linked immunosorbent assay of secreted interleukin-6 (IL-6) and IL-8 demonstrated that F. nucleatum induced production of these cytokines, whereas S. gordonii inhibited secretion from the epithelial cells. Stimulation of secretion of proinflammatory cytokines from epithelial cells may reflect the invasive phenotype of F. nucleatum and contribute to the greater pathogenic potential of F. nucleatum than of S. gordonii.

Solanum aethiopicum cultivation is highly constrained by Fusarium wilt. A trial was conducted to control soil-borne and seed-borne F. oxysporum f.sp. melongenae using botanicals (ginger and garlic extracts). Seeds of Bello variety of eggplant were used for the trial. The trial was set up using completely randomized design with nine treatments and each treatment replicated thrice. Data were collected on percentage germination, shoot height, number of leaves, plant vigour, shoot weight, disease incidence and disease severity. The results shows that treatment T9 has the lowest percentage germination (18.3%) at 7 DAS which is lower than T1 (44.2%) or mean (48.1%). T7 permits 72.5% germination which is at par with T6 (83.3%) at 15 DAS. Based on germination, T8, T5, T6 and T7 tops the chart (≥ 72.3% germination) compared to T9 (50.8%) at 15 DAS. The incidence of wilt is highest (33.4%) in T9 compared to all treated plots. T4, and T2 are the best treatments (0.0% incidence) at 45 DAS. Percentage severity of wilt follows the same trend as incidence. Based on shoot weight, T8 (8.3 g) and T7 (7.0 g) are the best treatments. The highest vigour index (45 DAS) is from T3 (823) followed by T2 (769), T5 (692), T7 (658) then T1 (604) in descending order of vigour index and mean vigour index is 582. It is concluded that the infection of eggplant by Fusarium sp. affects germination of seeds and subsequent growth in the absence of control measures. However, control of Fusarium sp. is possible with the use of botanicals.

SUMMARYHereford (H × H), Brahman × Hereford (B × H), Simmental × Hereford (S × H) and Friesian × Hereford (F × H) females born over a 5-year period (1973–77) were placed on pastures of high, medium or low nutritive value at Grafton, New South Wales, Australia, at weaning (7–8 months of age). The first mating of heifers on high pasture was at 15 months (1974) while that on medium and low pastures was delayed until 27 months of age (1975). This paper reports the reproductive performance of these cows up to 5 years of age and the preweaning growth of their calves which were sired by Hereford bulls at Grafton, Australia. In total, 1222 calving records were analysed.Most traits were subject to interaction between genotype and other main effects (pasture, year of birth of cow, cow age and sex of calf). Eyelid pigmentation was an exception, with calves from B × H cows having more than calves of other genotypes (73 v. 43%). There were significant genotype differences in calving difficulty among 2-year-old heifers only, with H × H (33%) requiring more assistance than F × H (15%) and SxH (10%) heifers, while B × H heifers did not require any assistance. Genotype differences in percentage of calves born and weaned were observed on low pastures only, where B × H (66% born, 65% weaned) exceeded H × H (48%, 39%) and S × H (39%, 38%) cows, with F × H (58%, 50%) cows being intermediate. Calves by H × H cows were the slowest-growing and were the lightest at weaning on all pastures, with mean gains of 759, 604 and 340 g/day, and mean weaning weights of 212, 188 and 110 kg, on high, medium and low quality pastures, respectively. F × H and S × H cows produced the fastest-growing calves on high quality pasture (966 and 936 g/day, respectively) while B × H cows produced the fastest-growing calves on medium (823 g/day) and low (679 g/day) quality pastures. F × H cows weaned the heaviest calves on high quality pasture (274 kg) while F × H and B × H weaned the heaviest calves on medium (230 and 229 kg, respectively) and low (162 and 169 kg, respectively) quality pastures. Differences in body measurements followed a pattern similar to weaning weight.

RESUMEN:El objetivo del artículo es aproximarnos a la controvertida biografía del comisario Manuel Brabo Portillo. El trabajo está basado en fuentes primarias y secundarias. El método utilizado es empírico. En el imaginario del mundo sindicalista revolucionario, Brabo Portillo era el policía más odiado, la reencarnación de la cara más turbia del Estado. Fue, así mismo, un espía alemán relacionado con el hundimiento de barcos españoles, el asesinato del empresario e ingeniero Barret y el primer jefe de los terroristas vinculados a la patronal barcelonesa. La conflictividad que afectó a España en el período de la Primera Guerra Mundial es fundamental para entender los orígenes del terrorismo vinculado al pistolerismo, que marcó la historia político social española del primer tercio del siglo XX.PALABRAS CLAVE: Brabo Portillo, pistolerismo, espionaje, sindicalismo, Primera Guerra Mundial.ABSTRACT:The objective of the article is an approach to the controversial biography of Police Chief Manuel Brabo Portillo. The work is based on primary and secondary sources. The method used is empirical. In the imagery of the revolutionary syndicalist world, Brabo Portillo was the most hated policeman, the reincarnation of the murkiest face of the state. He was also a German spy connected with the sinking of Spanish ships, the murder of businessman and engineer Josep Barret and the first head of the terrorists linked to Barcelona employers. 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FromRevolution to Dictatorship 1913-23, Houndmills, Basingstoke, Palgrave Macmillan, 2010.Rosenbusch, A., “Los servicios de información alemanes: sabotaje y actividad secreta”, Andalucía en la historia, 45 (2014), pp. 24-29.Rosenbusch, A., “Guerra Total en territorio neutral: Actividades alemanas en España durante la Primera Guerra Mundial”, Hispania Nova, 15 (2017), pp. 350-372.S. A., “Historia de un ‘bravo’ muy pillo”, La Campana de Gracia, 2569 (28/6/1918), p. 4.S.A., L’Esquella de la Torratxa, (12/7 y 30/8/ y 12/9/1918), pp. 447, 451, 456, 458, 568, 577 y 592.S. A., “A cada puerco le llega su San Martín” y “La muerte de Batet”, Solidaridad Obrera, 711 y 712 (9 y 10/1/1918), p. 1.S. A., Solidaridad Obrera, 713-716 (11-14/1/1918), p. 1.S. 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ABSTRACT Used of synthetic dye in the textile industry produced liquid waste if it is not recycle with properly, it can cause pollution and contamination of water both on the surface and every drop used by humans, disrupting ecosystems and even killing life in aquatic ecosystems. Therefore, an alternative to synthetic dye is neededby using plants as natural dye. Leaves can be used for their color content, leaf bones and leaf surfaces can be used as textile motif called ecoprint. This research purposing to find out the types of plants that can be used as materials for making ecoprint as a substitute for synthetic dye and also to find out the parts of plants that can be used as materialfor making ecoprint. The research method used is descriptive qualitative from literature study and literature references regarding data and information related to research. The results showed there are 30 types of plants that can be used in ecoprint. Thishabitus plants is herbaceous, vines, shrubs, shrubs and trees. From herbaceous habitus found 5 species of plants, 3 species of vine habitus, 7 species of bush habitus, 10 species of shrub habitus and 5 species of tree habitus. The parts of plants that can be used in making ecoprints are the leaves, flowers, stems and roots. The results showed there were 30 species of plants from 21 families that could be used in making ecoprint. The parts of plant can be used in making ecoprintare parts, leaves, flowers, stems and roots, but not all parts of every type of plant can be used in the process of making ecoprint. Keywords: Ethnobotanical Studies, Ecoprint, Synthetic Dyes, Natural Dyes, HabitusREFERENCE[1] Lubis, E. F. M. D., Ghea, A., Viola, D. E, dan Soraya, G. D. 2022. Pemanfaatan Daun dan Bunga Tanaman Buah sebagai Pewarna Motif Alami pada Media Jilbab dengan Teknik Ecoprint. Jurnal Senashtek, hal:819-823.[2]Juniar, , S., T. dan Sulandjari S. 2018. Perbedaan Hasil Rok Pias EcoprintDaun Jati (Tectona grandis) Menggunakan Jenis dan Massa Mordan Tawas dan Cuka. Jurnal Tata Busana, 7. [3] Martani, E., Margino S. dan Nurnawati E. 2011. Isolasi Dan Karakterisasi Jamur Pendegradasi Zat Pewarna Tekstil (Isolation and Characterization of Dye-degrading Fungi). Jurnal Manusia dan Lingkungan, 18, 127-136. [4] Subagyo, P., K. & Seolistyowati. 2021. Pengaruh Zat Pewarna Sintetis terhadap Pewarnaan Kain Batik. Jurnal FOLIO. Vol. 2., No., 2. [5]Komarawidjaja, W. 2016. Sebaran Limbah Cair Industri Tekstil dan Dampaknya pada Beberapa Desa Kecamatan Rancaekek Kabupaten Bandung. Jurnal Teknologi Lingkungan. Vol. 17. No. 2., hal: 118-125. [6] Enrico. 2019. Dampak Limbah Cair Industri Tekstil Terhadap Lingkungan dan Aplikasi Tehnik Eco Printing sebagai Usaha Mengurangi Limbah. Jurnal MODA. Vol.1., No. 1. [7] Masyitoh F. dan Ernawati E. 2019. Pengaruh Mordan Tawas dan Cuka Terhadap Hasil Pewarnaan Ecoprint Bahan Katun Menggunakan Daun Jati (Tectona grandis). Gorga Jurnal Seni Rupa, 8, 387-391. [8] Saraswati, R., M. H. Dewi, S., Ratri, C. R., Fajar, D. P. 2019. Pemanfaatan Daun untuk Ecoprint dalam Menunjang Pariwisata. Depok: Departemen Geografi FMIPA UI. [9] Wirawan, B., M. Alvin. 2019. Teknik Pewarnaan Alam Ecoprint Daun Ubi dengan Penggunaan Fiksator Kapur, Tawas dan Tunjung. Jurnal Litbang Kota Pekalongan: Vol. 17:1-5. [10] Simanungkalit, Y., S. 2020. Teknik Ecoprint dengan Memanfaatkan Limbah Mawar (Rosa Sp.) pada Kain Katun. Skripsi. Semarang: UNNES. [11] Sugiyono, 2013. Metode Penelitian Pendidikan Pendekatan Kuantitatif, Kualitatif; Research & Development. Bandung: Alfabeta. [12] Baharuddin A., Aisyah A., Saokani J. dan Risnah I. A. 2015. Karakterisasi Zat Warna Daun Jati (Tectona Grandis) Fraksi Metanol: N-Heksana sebagaiPhotosensitizer pada Dye Sensitized Solar Cell. Chimica et Natura Acta, 3. [13] Kembaren R., Putriliniar S., Maulana N., Yulianto K., Ikono r., Rochman N. T.dan Mardliyati, E. 2014. Ekstraksi dan Karakterisasi Serbuk Nano Pigmen dari Daun Tanaman Jati (Tectona grandis linn. F). Jurnal Kimia dan Kemasan, 36.[14] Sulistiawati E. dan Swastika P. 2017. Ekstraksi Zat Warna Alami dari Daun JatiMuda (Tectona grandis) dan Kayu Secang (Caesalpinia sappan) dengan Metode Ultrasound Assisted Extraction untuk Aplikasi Produk Tekstil. Skrispsi. Surabaya:InstitutTeknologi Sepuluh Nopember. [15] Koswara S. 2009. Pewarna Alami Produksi dan Penggunaannya. Ebook Pangan. [16] Haffida A. A. N. dan Rahardhian F. D. 2017. Ekstraksi Zat Tanin Dari Bahan Alami Dengan Metode Steam Extraction.Skrispsi. Surabaya:Institut Teknologi Sepuluh Nopember.

В 2018-2020 гг. исследована популяции оленька обыкновенного (Dorcus parallelipipedus L.), занесенного в Красную книгу Республики Татарстан, на территории парка «Крылья Советов» г. Казани. Установлено, что продолжительность периода активности жука составляет 95‒105 дней. Ведущим фактором динамики уловистости D. parallelipipedus на территории парка является температура воздуха. В 2019 г. произошло сильное смещение и сокращение сроков активности жука из-за пониженных температур во второй половине лета. К 2020 г. численность оленька сократилась в 2.4 раза. На это оказали влияние высокая рекреационная нагрузка в парке и погодные условия. Среди собранных жуков в большей мере преобладали погибшие особи (80%). Соотношение полов в популяции оленька обыкновенного в 2018 г. было оптимально равновесным, а в 2020 г. количество самок стало в 2.3 раза больше самцов. Библиографические ссылки 1. Берлов Э.Я., Кабакова О.Н. Атлас рогачей (Lucanidae) России // URL: https://www.zin.ru/Animalia/Coleoptera/rus/lucanida.htm (дата обращения: 21.01.2021). 2. Гершензон С.М. Основы современной генетики. Киев: Наукова думка, 1983. 558 с. 3. Красная книга Республики Татарстан: животные, растения, грибы. Казань: Природа, ТОО «Стар», 1995. 454 с. 4. Красная книга Республики Татарстан: животные, растения. Изд. 2-е. Казань: Идел–Пресс, 2006. 832 с. 5. Красная книга Республики Татарстан: животные, растения, грибы. Изд. 3-е. Казань: Идел–Пресс, 2016. 760 с. 6. Кузовенко А.Е., Киреева А.С., Мазяркина Т.Н. Находка оленька Dorcus parallelipipedus (Linnaeus, 1758) (Coleoptera:Lucanidae) в Казахстане // Кавказский энтомологический бюллетень. 2019. Т. 15, вып. 1. С. 59–60. 7. Экология города Казани. Казань: Изд-во «Фэн» Академии наук РТ, 2005. 576 с. 8. Alexander K.N.A., Mannerkoski I., Pettersson R., Mason F., Schmidl J. Dorcus parallelipipedus // The IUCN Red List of Threatened Species. 2010. e.T157667A5120866. 9. Bartolozzi L., Sprecher-Uebersax E. Lucanidae // Catalogue of Palaearctic Coleoptera. Vol. 3. Scarabaeoidea – Scirtoidea – Dascilloidea – Buprestoidea – Byrrhoidea. Apollo Books, Stenstrup, Denmark, 2006. P. 63–77. 10. Bartolozzi L., Ghahari H., Sprecher-Uebersax E., Zilioli M. A checklist of stag beetles (Coleoptera: Scarabaeoidea: Lucanidae) from Iran // Zootaxa. 2014. V. 3887, №3. P. 422–436. 11. Della Rocca F., Stefanelli S., Cardarelli E., Bogliani G., Bracco F. Contribution to the knowledge of the arthropods community inhabiting the winter-flooded meadows (marcite) of northern Italy // Biodiversity data journal. 2021. 9. e57889. https://doi.org/10.3897/BDJ.9.e57889. 12. Dorcus parallelipipedus (Linnaeus, 1758) in GBIF Secretariat. GBIF Backbone taxonomy. 2019. https://doi.org/10.15468/39omei. 13. Hardersen S., Ilaria T., Paolo C., Gianfranco C., Piero L., Gianluca N., Fabio P., Emanuele P., Giuseppe P. Survey of selected beetle families in a floodplain remnant in northern Italy // Bulletin of insectology. 2012. V. 65, №2. P. 199–207. 14. Paulsen M.J. Stag beetles of the genus Dorcus MacLeay in North America (Coleoptera, Lucanidae) // Current advances in Scarabaeoidea research. ZooKeys. 2010. V. 34. P. 199–207. DOI: 10.3897/zookeys.34.292. 15. Linnaei C. Systema Naturae Per Regna Tria Naturae, Secundum Classses, Ordines, Genera, Species, Cum Characteribus, Differentiis, Synonymis, Locis. Editio Decima, Reformata. Holmiae [Stockholm]: Impensis Direct. Laurentii Salvii. 1758. Bl. 823 p.

В результате прокладки трубопроводов и установки стоек высоковольтной линии электропередач в границах Елабужских и Танаевских лугов Национального парка «Нижняя Кама» были нарушен растительный и почвенный покровы. В работе проведена оценка сообществ педобионтов нарушенных и контрольных участков лугов. Показано сокращение таксономического состава и обилия мезофауны на трансформированных участках, численность в них педобионтов соответствовала показателям среднего и низкого значения. На контрольных участках обилие и таксономическое разнообразие мезофауны оставалось высоким. Список литературы Бакин О.В., Рогова Т.В., Ситников А.П. Сосудистые растения Татарстана. Казань: Изд-во Казанского ун-та, 2000. 496 с. Вавилов Д. Н., Суходольская Р. А., Гордиенко Т. А., Лукьянова Ю.А. Воздействие прокладки инженерных коммуникаций на крупных почвенных беспозвоночных // Российский журнал прикладной экологии. 2020. №2. С. 8‒16. Государственный реестр особо охраняемых территорий в Республике Татарстан. Казань: Идел-Пресс, 2007. 408 с. Гордиенко Т.А., Вавилов Д.Н., Лукьянова Ю.А. Структурная организация сообщества наземных и почвенных беспозвоночных на естественных и нарушенных участках Танаевских лугов Национального парка «Нижняя Кама» // Труды Мордовского государственного природного заповедника имени П.Г. Смидовича. 2021. Вып. 28. С. 38‒50. Гордиенко Т.А., Вавилов Д.Н., Суходольская Р.А., Лукьянова Ю.А. Влияние антропогенной трансформации луговых экосистем Национального парка «Нижняя Кама» на сообщества наземных и почвенных беспозвоночных // Российский журнал прикладной экологии. 2017. №3. С. 7‒11. Гордиенко Т.А., Суходольская Р.А., Вавилов Д.Н., Лукьянова Ю.А. Устойчивость луговых сообществ педобионтов при антропогенной нагрузке // Концептуальные и прикладные аспекты научных исследований и образования в области зоологии беспозвоночных / Сборник статей V Междунар. конф. Томск: Изд-во Томского государственного ун-та, 2020. С. 59‒62. Дорохов К.В., Шелухо В.П., Кистерный Г.А. Сравнительное влияние антропогенных факторов на состав, трофическую структуру и плотность мезофауны // Лесной журнал. 2016. №5. С. 9‒21. Кадастр сообществ почвообитающих беспозвоночных (мезофауна) естественных экосистем Республики Татарстан. Казань: Изд-во Казанского ун-та, 2014. 308 с. Методы почвенно-зоологических исследований. М.: Наука, 1975. 280 с. Bagaria G., Helm A., Rodá F., Pino, J. Assessing coexisting plant extinction debt and colonization credit in a grassland-forest change gradient // Oecologia. 2015. Vol. 179. P. 823‒834. doi:1007/s00442-015-3377-4. Clavel J., Julliard R., Devictor V., Worldwide decline of specialist species: toward a global functional homogenization? // Frontiers in ecology and the environment. Vol. 94. P. 222–228. doi: 10.1890/080216. Figueiredo L., Krauss J., Steffan-Dewenter I., Cabral J.S., Understanding extinction debts: spatio-temporal scales, mechanisms and a roadmap for future research // Ecography. 2019. Vol. 42. P. 1973‒1990. doi: 1111/ecog.04740 Krauss J., Bommarco R., Guardiol, M. Habitat fragmentation causes immediate and time delayed biodiversity loss at different trophic levels // Ecology Letters. 2010. Vol. 3. P. 597‒605. doi: 1111/j.1461-0248.2010.01457.x Kuussaari M., Bommarco R., Heikkinen R.K. Extinction debt: a challenge for biodiversity conservation // Trends in ecology & evolution. Vol. 24. P. 564‒571. doi: 10.1016/ j.tree.2009.04.011 Lӧffler F., Poniatowsk D., Fartmann T. Extinction debt across three taxa in well-connected calcareous grasslands // Biological conservation. 2020. Vol. 246. P. 108588. вoi: 1016/j.biocon.2020.108588 Buisson E., Fidelis A., Overbeck G.E., Schmidt I.B., Durigan G., Young T.P., Alvarado S.T., Arruda A.J., Boisson S., Bond W., Coutinho A., Kirkman K., Oliveira R.S., Schmitt M.H., Siebert F.,Siebert S.J., Thompson D.I., Silveira F.A.O. A research agenda for the restoration of tropical and subtropical grasslands and savannas // Restoration ecology. 2021. Vol. 29. P. e13528. doi: 1111/rec.13292 Török P., Vida E., Deák B., Lengyel S., Tóthmérész B. Grassland restoration on former croplands in Europe: an assessment of applicability of techniques and costs // Biodiversity and conservation. 2011. Vol. 20. P. 2311‒2332.

We present the temperature dependent elastic and ultrasonic properties of sodium borohydride. The second and third order elastic constants of NaBH4 have been computed in the temperature range 0-300K using Coulomb and Born-Mayer potential. The sodium borohydride crystallizes into NaCl-type structure. The computed values of second order elastic constants have been applied to evaluate the temperature dependent mechanical properties such as bulk modulus, shear modulus, tetragonal modulus, Poisson’s ratio and Zener anisotropy factor and ultrasonic velocity to predict futuristic information about sodium borohydride. The fracture to toughness ratio (bulk modulus/shear modulus) in sodium borohydride varied from 1.91 to 1.62, which shows its behavioral change from ductile to brittle on increasing the temperature. Then, ultrasonic Grüneisen parameters have been computed with the use of elastic constants in the temperature regime 100-300K. The obtained results have been discussed in correlation with available experimental and theoretical results. [1] A. Amudhavalli, M. Manikandan, A. Jemmy Cinthia, R. Rajeswarapalanichamy and K. Iyakutti, Z. Naturforsch. A 72 (2017) 321. [2] D.Singh, P.K.Yadawa and S.K.Sahu, Cryogenics 50 (2010) 476. [3] V. Bhalla, D.Singh and S.K.Jain, Int. J. Comput. Mat. Sc. Eng. 5 (2016) 1650012. [4] S. Kaushik, D. Singh and G. Mishra, Asian J. Chem. 24 (2012) 5655. [5] D. Chernyshov, A. Bosak, V. Dmitriev, Y. Filmchuk and H. Hagemann, Phys. Rev. B 78 (2008)172104. [6] H. Hagemann, S. Gomes, G. Renaudin and K. Yvon, J. Alloys Compd. 363 (2004) 126. [7] Y. Filinchuk, D. Chernyshov and V. Dmitriev, Z. Kristallogr. 223 (2008) 649. [8] Z.Xiao Dong, J.Z. Yi, Z. Bo, H. Z. Feng and H.Y. Qing, Chin. Phys. Lett. 28(2011)076201. [9] T. Ghellab, Z. Charifi, H. Baaziz, Ş. Uğur, G. Uğur and F. Soyalp, Phys. Scr. 91 (2016) 045804. [10] S. Bae, S. Gim, H. Kim and K. Hanna, Appl. Catal. B: Environm. 182 (2016) 541. [11] G. Renaudin, S. Gomes, H. Hagemann, L. Keller and K. Yvon, J Alloys Compd. 375 (2004) 98. [12] P. Vajeeston, P. Ravindran, A. Kjekshus and H. Fjellvåg, J Alloys Compd. 387 (2005) 97. [13] S. Orimo, Y. Nakamori, J.R. Eliseo, A. Zuttel and C. M. Jensen, Chem. Rev. 107 (2007) 4111. [14] A. Istek and E. Gonteki, J. Environ. Bio.7 (2009) 951. [15] R. S. Kumar and A.L. Cornelinus, Appl. Phys. Lett. 87 (2005) 261916. [16] E. Kim, R. Kumar, P. F. Weck, A. L. Cornelius, M. Nicol, S. C. Vogel, J. Zhang, M. Hartl, A.C. Stowe, L. Daemen and Y. Zhao, J. Phys. Chem. Lett. B 111 (2007) 13873. [17] K. Brugger, Phys. Rev. 133 (1964) A1611. [18] P.B. Ghate, Phy. Rev. 139 (1965) A1666 [19] S. Mori, Y. Hiki, J. Phys. Soc. Jpn. 45 (1975) 1449. [20] V. Bhalla, R. Kumar, C. Tripathy and D. Singh, Int. J. Mod. Phys. B 27 (2013) 1350116. [21] D. Singh, S. Kaushik, S. Tripathi, V. Bhalla and A. K. Gupta, Arab. J. Sci. Eng. 39 (2014) 485. [22] K. Brugger, Phys. Rev.137 (1965) 1826. [23] W. P. Mason, Physical Acoustics, vol. IIIB, Academic Press, New York, 1965. [24] M.P. Tosi, Solid State Physics, vol. 12, Academic Press, New York, 1965. [25] Y. Nakamori and S. Orimo, J. Alloy Compd.370(2004)271. [26] D. Singh, D.K. Pandey and P.K. Yadawa, Cent. Eur. J. Phys. 7 (2009) 198. [27] V. Bhalla, D. Singh, G. Mishra and M. Wan, J. Pure Appl. Ultrason. 38 (2016)23. [28] D. Singh, S. Kaushik, S.K. Pandey, G. Mishra and V. Bhalla, VNU J. Sc.: Math. Phys. 32(2016)43. [29] J.P.Watt and L. Peselnick, J.Appl. Phys. 51 (1980) 1525. [30] S.F.Pugh, Philos.Mag. 45 (1954) 823. [31] V. Bhalla, D. Singh and S.K. Jain, Int. J. Thermophys. 37(2016)33. [32] V. Bhalla, D. Singh, S.K. Jain and R. Kumar, Pramana- J. Phys. 86 (2016)135.

18201 Background: Based on the several clinical trials, combined modality therapy became the standard of care for patients with stage III NSCLC “unresectable” with good performance status (Kathy S. Albain, Educational Book ASCO 2006, 453–461; Thomas E. Stinchcombe, Oncologist 2006, 11, 809–823). The most effective induction chemotherapy has yet to be determined. The objective of this prospective phase I study was to define the maximum tolerated dose (MTD), and to evaluate the activity and safety of one of the third generation triplets as a full dose neoadjuvant regimen in patients (pts) with unresectable Stage III NSCLC. Methods: In this study, chemotherapy-naïve pts with stage IIIA-N2 bulky and IIIB (except malignant pleural effusion) NSCLC were eligible. Inclusion into the trial and treatment decisions were done by multidisciplinary panel involving surgeons, medical oncologists and radiotherapists. All drugs were given intravenously on days 1 and 8, and repeated every 3 weeks up to 2 cycles followed by concurrent chemoradiation. D (30–35 mg/m2) was given first, followed by C (35 mg/m2) and G (1000 mg/m2). Results: From Jan ‘06 to Jul ‘06 twelve eligible pts were enrolled, 10/2 m/f gender; median age 63 (50–72), 1 patient with ECOG PS 0, 11 pts with PS 1; 5 pts with stage IIIA-N2 bulky, 7 pts with stage IIIB NSCLC; nine pts were smokers. All pts were evaluable for toxicity. Toxicity grade 3–4 by CTC criteria was: grade 3 neutropenia in 2/3 patients and grade 3 thrombocytopenia in 1/3 patients on the second dose level of chemotherapy (i.e. docetaxel 35 mg/m2), and was considered dose-limiting. Of 9 pts treated at the MTD (i.e. docetaxel 30 mg/m2), only 1 patient developed grade 4 neutropenia and 1 patient grade 3 thrombocytopenia; 3 patients (30%) had grade 2 neutropenia and grade 2 stomatitis. Of 12 evaluable pts for response, after induction chemotherapy eighty-three percent of patients (9/12 pts) had an objective response and 16,6% (2/9 pts) stable disease. Phase II is continuing for larger patient accrual. Conclusions: The recommended doses for further phase II studies are D (30 mg/m2) followed by C (35 mg/m2) and G (1000 mg/m2) every 3 weeks. This regimen is well tolerated and effective, and appears to be an excellent choice for stage III NSCLC. No significant financial relationships to disclose.

Der von Karl Korinek und Michael Holoubek begründete Großkommentar bietet traditionell eine ebenso umfassende wie profunde Aufarbeitung des österreichischen Verfassungsrechts. Was vor mehr als zwanzig Jahren als Pionierprojekt begonnen hat, ist mittlerweile zum bestimmenden Referenzwerk für Wissenschaft und Praxis geworden. Der zwischenzeitlich um Christoph Bezemek, Claudia Fuchs, Andrea Martin und Ulrich E. Zellenberg ergänzte Kreis der Herausgeberinnen und Herausgeber verfolgt nach wie vor konsequent jenen Anspruch, der das Werk seit jeher ausgezeichnet hat: die Verbindung von unbedingter wissenschaftlicher Exzellenz mit größtmöglicher Aktualität. In zehn laufend ergänzten und aktualisierten Teilbänden vermessen führende Vertreterinnen und Vertreter des öffentlichen Rechts aus Wissenschaft und Praxis sämtliche Bestandteile der Grundordnung der Republik. Sie machen den "Korinek/Holoubek" damit nicht nur zu einem Zentralwerk der österreichischen Rechtsdogmatik, sondern auch zum Ankerpunkt jeder akademisch fundierten Auseinandersetzung mit der österreichischen Bundesverfassung. Die 17. Lieferung (Februar 2022) umfasst: Art 10/1 Z 6 2. Tb und Art 10/1 Z 6 3. Tb (Andreas Wimmer) Art 23e und Art 23k (Theodor Öhlinger/Christoph Konrath) Art 29/2-3 (Georg Lienbacher) Art 72 (Christoph Hofstätter) Art 78/1 (Bernd Wieser) Art 78a-d (Magdalena Pöschl) Art 90/2 (Christoph Herbst) Art 101 (Thomas Müller) Art 130/1a und Art 130/2a (Harald Eberhard) Art 131/3 und Art 131/4-6 (Thomas Ziniel) Art 133/1-2a und 9 (David Leeb) § 7 F-VG (Teilaustausch) und 17 F-VG (Hans-Georg Ruppe) Art 22 GRC (Jürgen Pirker) Art 38 GRC (Reinhard Klaushofer) Art 11 StGG (Ulrich E. Zellenberg) Aufbau des Gesamtwerkes: Band I/1: Art 1 bis 12 B-VG Band I/2: Art 13 bis 49b B-VG Band I/3: Art 50 bis 81c B-VG Band I/4: Art 82 bis 128 B-VG Band I/5: Art 129 bis 152 B-VG Band II/1: Europäische Menschenrechtskonvention samt Protokollen, Charta der Grundrechte Band II/2: Staatsgrundgesetz über die allgemeinen Rechte der Staatsbürger, BVG zum Schutz der persönlichen Freiheit sowie weitere Grundrechte (zB Grundrecht auf Datenschutz) Band III/1: Kommentar zum sonstigen Bundesverfassungsrecht: Internationale Beziehungen - Demokratische Grundordnung - Finanzverfassung - Staatsorganisation - Verfassungsaufträge und Staatszielbestimmungen - Energieverfassungsrecht Bände IV/1 und IV/2: Archiv

AbstractChapter 7 explained the detection and hypothesis testing problems, Huffman codes and the situation where errors are independent and Gaussian. In this chapter, we prove the optimality of the Huffman code in Sect. 8.1 and the Neyman–Pearson Theorem in Sect. 8.2. Section 8.3 discusses the theory of jointly Gaussian random variables that is used to analyze the modulation schemes of Sect. 7.5 . Section 8.4 uses the results on jointly Gaussian random variables to explain hypothesis tests that arise when analyzing data. That section discusses the chi-squared test and the F-test. Section 8.5 is devoted to the LDPC codes that are widely used in high-speed communication links. These codes augment a group of bits to be transmitted over a noisy channel with additional bits computed from those in the group. When it receives the bits, when the augmented bits are not consistent, the receiver attempts to determine the bits that are most likely to have been corrupted by noise.

Abstract Faddis, jon, tpt, flg, pno, comp, lead; b. Oakland, CA, 7/24/53. One sister sings, other pl. pno. Began on tpt. at age 8. Stud. w. Bill Catalano, who introduced him to Dizzy Gillespie’s music 1964. Later stud. improv. w. Bill Atwood; tpt. w. Carmine Caruso; Mel Broiles; Vince Penzarella. Stud. comp. w. Edgar Grana ’85–90. Pl. w. r&b bands in Oakland fr. age 13, then w. rehearsal bands in SF incl. Rudy Salvini; Cus Cousineau; Don Piestrup. Joined Lionel Hampton immediately after grad. hs ’71. Moved to NYC ’72, pl. w. Thad Jones–Mel Lewis Orch. ’72–5; Charles Mingus ’72–3; Gil Evans, Chuck Mangione ’72; Gillespie fr. ’74. Worked as studio mus. mid ’70searly ’80s. App. w. Gillespie at White House “In Performance” ’82. Pl. w. own qnt. fr. ’82; Philip Morris Superband, late ’80s. Faddis has also perf. and rec. w. Duke Ellington Orch.; Count Basie Orch.; Art Blakey; McCoy Tyner; Dexter Gordon; Cab Calloway; Joe Williams; Ella Fitzgerald; Sarah Vaughan; James Moody; Milt Jackson; etc. He served as mus. dir. of the Gillespie bb and the United Nation Orch. fr. ’87 to ’92; the Carnegie Hall 100th Anniv. bb ’91. Faddis has travelled extens. as a lecturer and clinician; in ’92 was appointed mus. dir. of the Carnegie Hall Jazz Band and in ’99 to the faculty of Purchase Coll. St. U., N.Y. Known for his mastery of the Gillespie style, often playing an octave higher than Dizzy, Faddis has brought other elements to his work from some of the Swing Era giants and personalized his playing. Tour. US, on own and w. LCJO ’94. Favs: Gillespie, Armstrong, Eldridge, M. Davis, C. Brown, Snooky Young. Polls: DB TDWR ’74–5. Fests: all major fr. ’77. Films: soundtracks for The Gauntlet; Bird; The Wiz; The Burning Spear; A Winter in Lisbon.

Abstract "At a date close to 495 BC king Kleomenes shipped the Spartan army across the Bay of Nauplia and brought the Argives to battle at Sepeia near Tiryns. The casualties were high, 6,000 according to Herodotos (7. 148. 2); after the battle (6. 83) their slaves (δoν λoi) took over the government and managed all the affairs of Argos, till the sons of the slain grew up and regained control. Plutarch (Mor. 245 F) contradicts Herodotos: it was not to the slaves that the Argives married their women in order to replenish their numbers, but to the best of the perioikoi. This is an appendix to the spurious story of the poetess Telesilla and the Argive women defending the walls against Kleomenes, and a careless addition since Herodotos had said nothing about marriage. But Aristotle (Pol. 1303a2-1o) tells us that their losses compelled them to admit to citizenship certain of the perioikoi, so in some form this correction goes back to the fourth century and already spoke of admitting a selection. It is not easy to take Herodotos‘ δoν λoi literally, and it is conjectured that his informants were aristocrats who were prepared to use this extreme term for persons whom they thought inferior; and these might be Aristotle‘s perioikoi.

Abstract author: See entry 92. translation: ANF 3.181–235. text: See entry 92; also J. H. Waszink, Tertullianus: “De Anima” (Amsterdam: North-Holland Publishing Co., 1947). bibliography: There is an extensive bibliography on Montanism (the New Prophecy): Blessings, 157–73; F. Forrester Church, “Sex and Salvation in Tertullian,” HTR 68 (1975): 83–101; Nicola Denzey, “What Did the Montanists Read,” HTR 94, no. 4 (2001): 427–49: Susanna Elm, “Montanist Oracles,” in Searching the Scriptures, 2:131–38; Frederick C. Klawiter, “The Role of Martyrdom and Persecution in Developing the Priestly Authority of Women in Early Christianity: A Case Study of Montanism,” Church History 49, no. 3 (1980): 251–61; John C. Poirier, “Montanist Pepuza-Jerusalem and the Dwelling Place of Wisdom,” JECS 7, no. 4 (1999): 491– 507; William Tabbernee, “Portals of the Montanist New Jerusalem: The Discovery of Pepouza and Tymion,” JECS 11, no. 1 (2003): 87–94; Christine Trevett, Montanism: Gender, Authority and the New Prophecy (Cambridge: Cambridge University Press, 1996). Additional sources for Montanism are collected in Ronald Heine, Montanist Oracles and Testimonia (Macon, Ga.: Mercer University Press, 1989); and William Tabbernee, Montanist Inscriptions and Testimonia: Epigraphic Sources Illustrating the History of Montanism, North American Patristic Society Patristic Monograph Series 16 (Macon, Ga.: Mercer University Press, 1997).

John F. Hartwig of the University of California, Berkeley devised (Science 2014, 343, 853) conditions for the regioselective silylation of an arene 1 to give 2. The silyl group can directly be converted, inter alia, to halo, amino, alkyl, or hydroxyl. Jin-Quan Yu of Scripps La Jolla effected (Angew. Chem. Int. Ed. 2014, 53, 2683) regioselective alkenylation of the arene 3 with 4 to give 5. Wei-Liang Duan of the Shanghai Institute of Organic Chemistry described (Org. Lett. 2014, 16, 500) a related alkenyl­ation protocol. Deping Wang of Henyang Normal University developed (Eur. J. Org. Chem. 2014, 315) inexpensive conditions for the conversion of an aryl bromide 6 to the corre­sponding phenol 7. Mamoru Tobisu and Naoto Chatani of Osaka University used (J. Am. Chem. Soc. 2014, 136, 5587) a Ni catalyst to convert the lactam 8 to the aryl boro­nate 9. Patrick J. Walsh of the University of Pennsylvania found (Adv. Synth. Catal. 2014, 356, 165) conditions for the clean monoarylation of the amide 11 with 10 to give 12. In an application of the Catellani approach, Zhi- Yuan Chen of Jiangxi Normal University coupled (Chem. Eur. J. 2014, 20, 4237) the aryl iodide 13 with 14 to give the amino ester 15. Frederic Fabis of the Université de Caen-Basse-Normandie used (Chem. Eur. J. 2014, 20, 7507) Pd to catalyze the ortho halogenation (and alkoxylation) of the N-sulfonylamide 16 to give 17. Wen Wan of Shanghai University and Jian Hao of Shanghai University and the Shanghai Institute of Organic Chemistry effected (Chem. Commun. 2014, 50, 5733) ortho azidination of the aniline 18 with 19, leading to 20. Jianbo Wang of Peking University found (Angew. Chem. Int. Ed. 2014, 53, 1364) that the N-aryloxy amide 21 could be combined with the α-diazo ester 22 to give the ortho-alkenyl phenol 23. Silas P. Cook of Indiana University uncovered (Org. Lett. 2014, 16, 2026) remarkably simple conditions for the enantiospecific cyclization of 24 (65% ee) to 25 (63% ee). The development of arynes as reactive intermediates continues unabated. Xiaoming Zeng of Xi’an Jiaotong University developed (Org. Lett. 2014, 16, 314) the reagent 27 for the bis-functionalization of the aryne derived from 26.

Erick M. Carreira at ETH Zürich reported (Science 2013, 340, 1065) the enantiose­lective α-allylation of aldehyde 1 with alcohol 2 to produce 3 using a dual catalytic system involving a chiral iridium complex and amine 5. This stereodivergent method allows access to all of the possible stereoisomers of 3. In a conceptually related proc­ess, John F. Hartwig at the University of California, Berkeley reported (J. Am. Chem. Soc. 2013, 135, 2068) the highly stereoselective allylic alkylation of azlactone 6 with allylic carbonate 7 catalyzed by a combination of Ir(cod)Cl₂, ligand 9, and racemic silver phosphate 10. An enantioselective three-component Mannich-type reaction of tert-butyl diazo­acetate, aniline, and imine 11 to produce α,β-bis(arylamino) acid derivative 13 under dual catalysis with Rh₂(OAc)₄ and acid 12 was developed (Synthesis 2013, 45, 452) by Wenhao Hu at the Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development. Keiji Maruoka at Kyoto University reported (Chem. Commun. 2013, 49, 1118) a one-pot cross double-Mannich reaction of acetylalde­hyde 14, and imines 16 and 17 using axially chiral amino sulfonamide 15 to obtain densely functionalized 1,3-diamine 18 as a single stereoisomer. Jeffrey S. Johnson at the University of North Carolina at Chapel Hill reported (Org. Lett. 2013, 15, 2446) the asymmetric synthesis of enantioenriched anti-α-hydroxy-β-amino acid derivative 21 from 19 by treatment with oxone followed by catalytic hydrogenation using Ru(II) complex 20. Naoya Kumagai and Masakatsu Shibasaki at the Institute of Microbial Chemistry found (Org. Lett. 2013, 15, 2632) that a sil­ver complex of bisphosphine 24 effected a syn-selective and highly enantioselective Mannich-type reaction of aldimine 22 and α-sulfanyl lactone 23 to furnish the stereo­diad 25 with very high ee. The enantioselective homocrotylation of octanal 26 with cyclopropylcarbinylbo­ronate 27 to produce alcohol 28 with high ee was disclosed (J. Am. Chem. Soc. 2013, 135, 82) by Isaac J. Krauss at Brandeis University with computational studies pro­vided by Kendall N. Houk at UCLA. Benjamin List at the Max-Planck-Institut für Kohlenforschung reported (J. Am. Chem. Soc. 2013, 135, 6677) the enantioselective epoxidation of cyclohexenone 29 utilizing cinchona alkaloid- derived catalyst 30.

This article proposes and implements a relationship model between the perceived economic value of computer operating systems (OSs) and their usability where all the model variables are evaluated by the generative artificial intelligence (AI) robot Copilot of Microsoft. In the underlying study, the perceived economic value of a particular OS was estimated by a proxy variable, namely, the OS’s total cost of ownership (TCO) whereas the usability of the OS was gauged by eight usability variables corresponding to the eight major usability dimensions (1) Effectiveness, (2) Efficiency, (3) Learnability, (4) Memorability, (5) Safety, (6) Utility, (7) Ergonomics, and (8) Accessibility. All these variables were evaluated on a scale of 1 (the lowest or worst, as appropriate) to 10 (the highest or best, as appropriate) by the robot Copilot based on global users’ textual comments on the TCO and the above eight dimensions of the OS as appear all around the web. A total of 18 OSs were covered in the modeling, they being the popular versions of the three leading OS families of Microsoft Windows, Apple macOS, and Linux. Multiple regression of the TCO on the eight usability variables was performed, followed by individual simple regression of the TCO on each of the eight usability variables in a bid to avert multicollinearity’s effect. On the one hand, the multiple regression rendered a model with a coefficient of determination R2 = .853 and an F-statistic = 8.290 (df = 7, 10; p = 0.002 < 0.01) and (2) Efficiency being the only usability variable statistically significantly (p < 0.05) but negatively impinging on the TCO. On the other hand, the individual simple regression models revealed that in an individual manner, (2) Efficiency (R2 = 0.562; F = 20.542 (df = 1, 16; p = .000)), (5) Safety (R2 = .547; F = 19.335 (df = 1, 16; p = .000)), (6) Utility (R2 = .392; F = 10.331 (df = 1, 16; p = .005)), and (7) Ergonomics (R2 = .253; F = 5.431 (df = 1, 16; p = .033)) all statistically significantly but negatively impacted the TCO. Deducing from these models, the better an OS in these four usability dimensions, the lower its economic value as perceived by the market was. In other words, the market of OSs did not seem to have priced in usability or seemed to have even priced in them in a direction at odds with intuition and logic. These confounding results may be ascribable to multicollinearity and probably imperfection of the current generative AI technology, on which this study heavily hinged. After all, the multiple regression model predicts and explains the TCO and thus the perceived economic value very well.

Purpose: The aim of this study was to analyze the effects of different resistance training (RT) volumes on muscle strength and functional capacity in breast cancer survivors (BCS) undergoing hormone therapy (tamoxifen® oranastrozol). Methods: A total of 13 untrained women breast cancer survivors were randomized to one of the following TR groups: high resistance training volume (HRTV: 6 women; 57.0±8.3 years old; height: 1.59±0.0 m; body mass 63.7±7.61 kg) or low resistance training volume (LRTV: 7 women; 55.1±7.4 years old; height: 1.58 ±0.0 m; body mass: 59.8±15.1 kg). Participants performed a full-body RT routine (e.g. leg press, bench press, lat pulldown, stiff, and sit-up) once a week for 8 weeks. All exercise sets were performed until momentary muscle failure within a range of predefined repetitions in both groups HRTV (12–15 repetitions) and LRTV (6–8 repetitions), in a total of three sets for each exercise. Upper and lower limb strength was evaluated by the 10-repetition maximum test using the bench press and leg press, respectively. Functional capacity was assessed by the Timed Up and GO test. Results: Both groups showed changes in performance variables (bench press — F=36.35, p<0.001), and in functional capacity (F=13.84, p=0.003), regardless of protocol used (HRTV and LRTV), with no differences between groups. Conclusion: Both protocols used in the present study (HRTV and LRTV) when prescribed in a supervised manner and in minimum weekly doses can contribute to the increase in strength of upper and lower limbs in a similar way and, consequently, can provide improvements in the functional capacity of BCS under hormone therapy treatment.

Abstract Alloy 82/182 Dissimilar Metal (DM) butt welds have been the subject of significant work due to their susceptibility to primary water stress corrosion cracking (PWSCC). The current rules for inspection of DM butt welds are contained in ASME Code Case N-770 (latest revision). These rules are based on crack growth rates that were originally published in MRP-115 in 2004. Since that time significant work has been performed to better understand the crack growth behavior of Alloy 82/182 materials in pressurized water reactors (PWRs) and updated crack growth rates have recently been published in MRP-420 (Rev. 1). These updated crack growth rates show a significant difference at lower temperatures which line up with the cold leg temperatures for PWRs (approx. 540–560°F). Additionally, the US Nuclear Regulatory Commission (NRC) working along with the Electric Power Research Institute (EPRI) recently released the xLPR computer code which is a probabilistic fracture mechanics code for evaluating DM butt welds. This paper evaluated various cold leg DM butt welds for PWRs using the xLPR probabilistic computer code to determine if a change in the frequency between inspections for unmitigated DM butt welds (Item B-1) from their current requirements in ASME Code Case N-770 is warranted. Failure probabilities were determined for the current technical basis using MRP-115 crack growth rates (with the current inspection duration) and compared to the probabilities using the new crack growth rates in MRP-420, Rev. 1 (with increased inspection durations). The evaluation results demonstrate that the duration between volumetric examinations for small and medium diameter DM butt welds from Code Case N-770, Inspection Item B-1, can be safely increased to once per 10-year ISI interval from the current requirement of once every 7 years when the specific requirements described in this paper are met.

According to the Bronfenbrenner's ecological systems theory of human development ([1][2][3][4][5]), the development of each individual cannot be observed without considering its relationship with the development of other people and, above all, with the environment in which they live. The ecological orientation of Bronfenbrenner with respect to human development is therefore based on the interest in the progressive adaptation between an active organism that grows and its immediate environment: the individual-environment interaction that is determined by the relationships existing between the different environmental situations and the individuals present in that context is fundamental. Consequently, the ecological environment that is considered relevant to development processes is not limited to a single environmental situation but includes the interconnections between multiple environmental situations and the different influences of each individual. The evolution of the Internet-based technologies has brought to the development of solutions that have profoundly changed the way we live, including education. The advent of social media and social networks represents a milestone in the history of Internet, opening up to profound reflections on the "virtualization" of relationships, their growing importance in everyday life, and their role in education. Many authors argue that the Internet and the social media should no longer be considered as a tool to connect to a virtual reality that is separate from the real world, but as a place in which users live daily ([6][9][11][10]); consequently, they constitute one of the environmental situations mentioned by Bronfenbrenner. However, the risks deriving from the use of social media have been widely discusses in the literature ([7][8][12]). Adolescents are more exposed to the social media threats, since they are unable to perceive the profoundly different dynamics that govern offline and online networks. In this paper, having in mind the Bronfenbrenner's ecological systems theory of human development, we argue that the progressive adaptation of students to social media should be considered as a process of their growth and development. Furthermore, we analyze some corrections to be introduced in the educational paths of adolescents necessary to reduce the threats deriving from the use of social media and social networks in education. Reference Text and Citations [1] Bronfenbrenner, U. (1961). Toward a theoretical model for the analysis of parent-child relationships in a social context. In J. C. Glidewell (Ed.), Parental attitudes and child behavior (pp. 90-109). Springfield, IL: Charles C. Thomas. [2] Bronfenbrenner, U. (1973). Social ecology of human development. In F. Richardson (Ed.), Brain and intelligence: The ecology of child development (pp. 113-129). Hyattsville, MD: National Education Press. [3] Bronfenbrenner, U. (1974). Developmental research, public policy, and the ecology of childhood. Child Development, 45, 1-5. https://doi.org/10.2307/1127743 [4] Bronfenbrenner, U. (1994). Ecological models of human development. In T. Husen & T. N. Postlethwaite (Eds.), International encyclopedia of education (2nd ed., Vol. 3, pp. 1643-1647). Oxford, UK: Pergamon Press and Elsevier Science. [5] Bronfenbrenner, U., & Morris, P. A. (2006). The bioecological model of human development. In W. Damon (Series Ed.) & R. M. Lerner (Vol. Ed.), Handbook of child psychology: Theoretical models of human development (pp. 793-828). New York, NY: Wiley. [6] Carr, N. (2011). The Shallows: What the Internet Is Doing to Our Brains. New York: W.W. Norton & Company. [7] Livingstone, S., Haddon, L., G?rzig, A., & ?lafsson, K. (2011). Risks and safety on the internet: The perspective of European children. Full Findings. London: EU Kids Online, LSE. [Google Scholar] [8] Martin, F., Wang, C., Petty, T., Wang, W., & Wilkins, P. (2018). Middle school students' social media use. Journal of Educational Technology & Society, 21(1), 213-224. https://www.jstor.org/stable/26273881 [9] Musetti, A., Cattivelli, R., Giacobbi, M., Zuglian, P., Ceccarini, M., Capelli, F., et al. (2016). Challenges in internet addiction disorder: is a diagnosis feasible or not? Frontiers in Psychology, 7. doi: 10.3389/fpsyg.2016.00842 [10] Musetti, A., Cattivelli, R., Zuglian, P., Terrone, G., Pozzoli, S., Capelli, F., et al. (2017). Internet addiction disorder o internet related psychopathology? [Internet Addiction disorder or Internet Related Psychopathology?]. Giornale Italiano di Psicologia, 44, 359-382. doi: 10.1421/87345 [11] Taymur, I., Budak, E., Demirci, H., Akdag, H.A., Gungor, B.B., & Ozdel, K. (2016). 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F 68070, an oxime-alkane carboxylic acid derivative (Janssen Pharmaceutica), is a potent inhibitor of thromboxane A2 (TXA2) synthetase activity (IC50 in vitro against thrombin-stimulated human platelets in plasma : R 68070 : 2.9 x 10-8 M; CGS 13080 : 6 x 10-8 M; OKY-1581 : 8.2 x 10-8 M; dazmegrel : 2.6 x 10-8 M; dazoxiben : 2.3 x 10-8 M).The compound specifically inhibits platelet TXA2 synthetase activity (14C-arachidonic acid metabolism by washed human platelets) without effect on the cyclo-oxygenase, lipoxygenase (platelets, RBL cells) or prostacyclin synthetase activities (rat aortic rings).The inhibitory effect of R 68070 against human platelet TXA2 synthetase activity increases upon prolongation of the contact time (ICsg at 0.5 min of contact : 5.2 x 10-7 M; at 5 min : 8.3 x 10-8 M; at 30 min : 2.5 x 10-8 M) and is reversed by washing of the platelets.In vivo, the compound has a comparatively strong inhibitory effect on platelet TXA2 synthetase activity after oral administration to rats (ED50 - 2 h : R 68070 0.013 mg/kg; CGS-13080 : 0.8 mg/kg; OKY-1581 : 0.61 mg/kg; dazmegrel : 1 mg/kg; dazoxiben : 4.1 mg/kg) and a protracted duration of action in rats and dogs (inhibition 8 h after 1.25 mg/kg orally > 80 %).In vitro, R 68070 inhibits the aggregation of human platelets in plasma stimulated with collagen (IC50 : 4 x 10-6 M), but also with U 46619 (IC50 : 3.8 x 10-6 M) without affecting the primary aggregation reaction elicited by ADP, 5-HT or adrenaline. The compound thus also produces platelet TXA2/prostaglandin endoperoxide receptor blockade.In rats and in dogs R 68070 (1.25 mg/kg I.V.) potently prevents thrombus formation in carotid and coronary arteries damaged by electrical stimulation.The combination of platelet TXA2 synthetase inhibition with TXA2/prostaglandin endoperoxide blockade in one molecule thus might offer an improved anti-thrombotic effectiveness.

With deepening ocean development , a larger scale Internet of Underwater Things (IoUT) is being realized[1].More and more underwater equipment is being deployed, various ocean monitoring equipment, underwater robots and underwater group sites amongst others, all of which will be working in the deep sea for long periods of time in the foreseeable future[2].Due to the increasing working time and power consumption, it has become difficult for the high energy batteries carried by these facilities to cover their energy needs [3]. Therefore, it is necessary to solve the problem of electrical energy replenishment for underwater equipment.Based on Equinor’s Underwater Intervention Drone (UID) standard interface definition, Blue Logic have produced the world's first three universal, open-standard subsea drone docking stations.But this is not perfect, in the face of deeper waters, more complex multi-shape deep sea equipment charging needs, the current program is not enough to solve[4].Therefore, based on the IoUT scenario positioning, this research designs a subsea charging station that can serve multiple devices.The concept is similar to a land-based collection station for power banks, providing multiple sub-charging equipment that can be carried on the move to charge multiple subsea equipments of different types simultaneously.It also uses ocean energy to provide in-situ produced electricity for the underwater charging base station .Compared to Blue Logic's Subsea Drone Docking Station (SDS), it enables the multi-device charging needs of the IoUT using ultrasonic technology[5,6].In the long term, the combination of existing equipment will greatly reduce the cost of regional subsea long-term exploration and expand the scope of exploration[7].The paper will solve the following problems:1) How to solve the charging problem of long-distance survey of underwater equipments（e.g. AUV）?2) How to make the design applicable to charging usage scenarios common to different types, forms and sizes of underwater equipments?3) How to design underwater charging energy transmission more efficiently and sustainably?The research approach composed following parts:- Through literature research, sort out the development status of technical equipment such as underwater charging, underwater docking, underwater information transmission and marine power generation.- A structure interview with the opinions of deep-sea equipment designers and researchers to clarify the design requirements. - Analyze product features and problems and summarize the design process and direction through brainstorming method and solution building method.The design of the underwater multi-port charging base station solves the energy problem of deep-sea long-term survey equipment, with poor energy sustainability and low charging efficiency.This approach will enable true continuous subsea operations in extremely dynamic ocean environments.Although the project is still a conceptual design and various sensors are still being experimented with, it is forward-looking and instructive for future applications.References1.Wang X., Lu J., Peng W., &Song L.,(2021) Accelerating the construction of marine "new infrastructure" and promoting high-quality development of marine industry,Science & Technology Review,39(16),pp.76-80.2.Qu, Feng-Chong, Lai. , Liu, J.-Z., Tu, X.-B., Jiang, Y.,(2021)'Research and Application of Key Technologies for Marine Internet of Things', Telecommunications Science, 37, (7), pp. 25-33.3.Tian Y., Yuan R.,&Li X.,(2018)'Design and experiment of deep-sea microcurrent power generation system', Acta Energiae Solaris Sinica,Journal of China Academy of Electronics and Information Technology, 39, (4), pp. 873-878.4.SubseaDockingStation(SDS).[Online].Available:https://www.bluelogic.no/news-and-media/subsea-docking-station-sds-.5.Abicht, D., Torvestad, J.C., Solheimsnes, P.A., and Stenevik, K.A., ‘Underwater Intervention Drone Subsea Control System’, in Proceedings of the OTC, 2020.6.Wang Y., &Tian F.,(2019)'Research on acoustic wave-based charging planning in underwater sensing networks',Journal of China Academy of Electronics and Information Technology,14(11),pp.1183-11877.Cruz, N.A., Matos, A.C., Almeida, R.M., and Ferreira, B.M.: ‘A lightweight docking station for a hovering AUV’, in Proceedings of the IEEE, 2017, pp. 1-7.

Tomato yellow leaf curl virus (TYLCV) is one of the most devastating viruses of cultivated tomatoes. Although first identified in the Mediterranean region, it is now distributed world-wide. Sequence analysis of the virus by the Australian group has shown that the virus is now present in Australia. Despite the importance of the disease and extensive research on the virus, very little is known about the resistance genes (loci) that determine host resistance and susceptibility to the virus. A symptom-less resistant line, TY-172, was developed at the Volcani Center which has shown the highest resistance level among all tested varieties. Preliminary results show that TY-172 is a good candidate to confer resistance to both TYLCV and to Tomato leaf curl virus (ToLCV) in Queensland conditions. Furthermore, Segregation analysis has previously indicated that the resistance is determined by 2-3 genes. In this proposal we aimed to substantiate that TY-172 can contribute to resistance breeding against TYLCV in Queensland, to develop DNA markers to advance such resistance breeding in both Israel and Queensland, and to exploit these markers for resistant breeding in Australian and Israeli lines. To map quantitative trait loci (QTLs) controlling TYLCVresistance in TY172, appropriate segregating populations were analyzed using 69 polymorphic DNA markers spanning the entire tomato genome. Results show that TYLCV resistance in TY172 is controlled by a previously unknown major QTL, originating from the resistant line, and four additional minor QTLs. The major QTL, termed Ty-5, maps to chromosome 4 and accounts for 39.7-to-46.6% of the variation in symptom severity among segregating plants (LOD score: 33-to-35). The minor QTLs, originated either from the resistant or susceptible parents, were mapped to chromosomes 1, 7, 9 and 11, and contributed 12% to the variation in symptom severity in addition to Ty-5. Further analysis of parental lines as well as large F₁, BC₁F₁, F₂ and BC₁F₂ populations originating from crosses carried out, in reciprocal manner, between TY172 and the susceptible processing line M-82 (LA3475) during spring-summer 2010, indicated that: (1) the minor QTLs we have previously identified are in effect not reproducible, (2)Ty-5 alone can yield highly resistant plants with practically no extra-chromosomal effects, and (3) the narrow-sense heritability estimate of resistance levels, attributed to additive factors responsive to selection, does not significantly deviate from 1. All of these results point to Ty-5 as the sole resistance locus in TY172 thus significantly increasing the likelihood of its successful molecular dissection. The DNA markers developed during the course of this study were transferred together with the TY172 genotype to Queensland. TY172 was crossed to a panel of Australian genotypes and the resulting populations were subjected to segregation analysis. Results showed that resistant locus, Ty-5, is highly reproducible in the Australian conditions as well. The Australian group was also able to make improvements to the marker assays by re-designing primer pairs to provide more robust PCR fragments. The Ty-5 locus has now been introgressed into elite Australian germplasm and selection for TYLCV resistance has begun. Cumulatively, our results show that Ty-5 can be effectively used, together with the TY172 genotype to expedite TYLCV resistance breeding and improve our understanding of the genetics that underline the response of tomato to TYLCV. Contributions to agriculture include: (1) the development of tools for more efficient resistance breeding, allowing the incorporation of resistance to local tomato varieties in Australia, Israel and elsewhere; and (2) establish a solid framework for a future attempt to clone the genes that encode such resistance. The latter will enable to decipher the resistance mechanisms that could be applied to other geminiviruses in tomato and possibly in other plant species.