Journal articles: '62R07'

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Aribawati, Diesta, Firosalia Kristin, and Indri Anugraheni. "PENERAPAN MODEL PEMBELAJARAN INKUIRI TERBIMBING UNTUK MENINGKATKAN KREATIVITAS DAN HASIL BELAJAR IPA SISWA KELAS 3 SD." Justek : Jurnal Sains dan Teknologi 1, no. 1 (April 18, 2018): 70. http://dx.doi.org/10.31764/justek.v1i1.407.

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Abstrak: Penelitian ini bertujuan untuk meningkatkan kreativitas dan hasil belajar IPA siswa. PTK adalah jenis penelitian yang digunakan dalam penelitian ini. Subjek penelitian adalah siswa kelas 3 SD Negeri Tegalrejo 01 yang berjumlah 29 siswa. Teknik pengumpulan data yang digunakan adalah teknik tes, observasi, dan dokumentasi. Teknik analisis data yang digunakan berupa deskriptif kuantitatif dan kualitatif. Hal ini dilihat dari peningkatan kreativitas belajar pra siklus sebesar 41,38% meningkat menjadi 62,07% pada siklus I dan 89,65% pada siklus II. Sedangkan untuk hasil belajar pra siklus menunjukkan ketuntasan belajar sebesar 37,93% kemudian meningkat pada siklus I menjadi 65,52% dan 93,10% pada siklus II. Abstract: This study aims to improve the creativity and learning outcomes of science students. PTK is the type of research used in this study. The subjects of the study were the 3rd graders of SD Negeri Tegalrejo 01, which amounted to 29 students. Data collection techniques used are test techniques, observation, and documentation. Data analysis techniques used in the form of descriptive quantitative and qualitative. This is seen from the increase of pre-cycle learning creativity by 41.38% increased to 62.07% in the first cycle and 89.65% in cycle II. While for pre-cycle learning result show mastery learn equal to 37,93% then increase in cycle I become 65,52% and 93,10% in cycle II.

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Marcelin, Anne-Geneviève, Charlotte Charpentier, Aude Jary, Marine Perrier, Nicolas Margot, Christian Callebaut, Vincent Calvez, and Diane Descamps. "Frequency of capsid substitutions associated with GS-6207 in vitro resistance in HIV-1 from antiretroviral-naive and -experienced patients." Journal of Antimicrobial Chemotherapy 75, no. 6 (March 10, 2020): 1588–90. http://dx.doi.org/10.1093/jac/dkaa060.

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Abstract Background GS-6207 is a first-in-class HIV capsid inhibitor, targeting several functions of the HIV capsid in the viral cycle, including viral particle assembly, capsid formation and nuclear entry. GS-6207 has demonstrated picomolar potency in vitro, activity confirmed by high potency in a Phase 1 clinical study, with a long-acting antiretroviral profile with potential dosing every 6 months. In vitro resistance selections previously conducted with increasing doses of GS-6207 have identified capsid variants with reduced susceptibility to GS-6207. Objectives To study the prevalence of capsid mutations associated with in vitro resistance to GS-6207 in people living with HIV (PLWH). Methods Plasma samples from ART-naive or -experienced PLWH, including PI-experienced people, were sequenced and analysed for the presence of capsid variants identified during in vitro resistance selection: L56I, M66I, Q67H, K70N, N74D, N74S and T107N. Results Among the samples from the 1500 patients studied, none of the seven GS-6207 resistance mutations identified during in vitro selection experiments was detected, regardless of HIV subtype or PLWH treatment history. Conclusions Out of the seven HIV capsid substitutions previously selected in vitro and shown to confer phenotypic resistance to GS-6207, none of these seven mutations was observed in this large dataset, suggesting that neither PLWH with previous PI failure nor PLWH with emergence of PI resistance mutations are anticipated to impact GS-6207 activity in these diverse HIV-infected populations.

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Bester, Stephanie M., Guochao Wei, Haiyan Zhao, Daniel Adu-Ampratwum, Naseer Iqbal, Valentine V. Courouble, Ashwanth C. Francis, et al. "Structural and mechanistic bases for a potent HIV-1 capsid inhibitor." Science 370, no. 6514 (October 15, 2020): 360–64. http://dx.doi.org/10.1126/science.abb4808.

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The potent HIV-1 capsid inhibitor GS-6207 is an investigational principal component of long-acting antiretroviral therapy. We found that GS-6207 inhibits HIV-1 by stabilizing and thereby preventing functional disassembly of the capsid shell in infected cells. X-ray crystallography, cryo–electron microscopy, and hydrogen-deuterium exchange experiments revealed that GS-6207 tightly binds two adjoining capsid subunits and promotes distal intra- and inter-hexamer interactions that stabilize the curved capsid lattice. In addition, GS-6207 interferes with capsid binding to the cellular HIV-1 cofactors Nup153 and CPSF6 that mediate viral nuclear import and direct integration into gene-rich regions of chromatin. These findings elucidate structural insights into the multimodal, potent antiviral activity of GS-6207 and provide a means for rationally developing second-generation therapies.

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Akther, Thamina, William M. McFadden, Huanchun Zhang, Karen A. Kirby, Stefan G. Sarafianos, and Zhengqiang Wang. "Design and Synthesis of New GS-6207 Subtypes for Targeting HIV-1 Capsid Protein." International Journal of Molecular Sciences 25, no. 7 (March 27, 2024): 3734. http://dx.doi.org/10.3390/ijms25073734.

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HIV-1 capsid protein (CA) is the molecular target of the recently FDA-approved long acting injectable (LAI) drug lenacapavir (GS-6207). The quick emergence of CA mutations resistant to GS-6207 necessitates the design and synthesis of novel sub-chemotypes. We have conducted the structure-based design of two new sub-chemotypes combining the scaffold of GS-6207 and the N-terminal cap of PF74 analogs, the other important CA-targeting chemotype. The design was validated via induced-fit molecular docking. More importantly, we have worked out a general synthetic route to allow the modular synthesis of novel GS-6207 subtypes. Significantly, the desired stereochemistry of the skeleton C2 was confirmed via an X-ray crystal structure of the key synthetic intermediate 22a. Although the newly synthesized analogs did not show significant potency, our efforts herein will facilitate the future design and synthesis of novel subtypes with improved potency.

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Sun, Qinfang, Ronald M. Levy, Karen A. Kirby, Zhengqiang Wang, Stefan G. Sarafianos, and Nanjie Deng. "Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation." Viruses 13, no. 5 (May 15, 2021): 920. http://dx.doi.org/10.3390/v13050920.

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While drug resistance mutations can often be attributed to the loss of direct or solvent-mediated protein−ligand interactions in the drug-mutant complex, in this study we show that a resistance mutation for the picomolar HIV-1 capsid (CA)-targeting antiviral (GS-6207) is mainly due to the free energy cost of the drug-induced protein side chain reorganization in the mutant protein. Among several mutations, M66I causes the most suppression of the GS-6207 antiviral activity (up to ~84,000-fold), and only 83- and 68-fold reductions for PF74 and ZW-1261, respectively. To understand the molecular basis of this drug resistance, we conducted molecular dynamics free energy simulations to study the structures, energetics, and conformational free energy landscapes involved in the inhibitors binding at the interface of two CA monomers. To minimize the protein−ligand steric clash, the I66 side chain in the M66I−GS-6207 complex switches to a higher free energy conformation from the one adopted in the apo M66I. In contrast, the binding of GS-6207 to the wild-type CA does not lead to any significant M66 conformational change. Based on an analysis that decomposes the absolute binding free energy into contributions from two receptor conformational states, it appears that it is the free energy cost of side chain reorganization rather than the reduced protein−ligand interaction that is largely responsible for the drug resistance against GS-6207.

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Madan, Ravi Amrit, Nishith K. Singh, Ann Wild Gramza, Antonio Tito Fojo, Christopher Ryan Heery, Joseph W. Kim, Sheri McMahon, et al. "A phase II study of a yeast-based therapeutic cancer vaccine, GI-6207, targeting CEA in patients with minimally symptomatic, metastatic medullary thyroid cancer." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): TPS3127. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.tps3127.

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TPS3127 Background: Saccharomyces cerevisiae has been genetically modified to express CEA protein and developed under a CRADA with GlobeImmune/NCI as a heat-killed immune-stimulating, therapeutic cancer vaccine (GI-6207). A phase I study with GI-6207 demonstrated safety, biomarker stabilization and enhanced immune response in some patients. CEA is over-expressed in multiple malignancies, including medullary thyroid cancer (MTC). Two therapies recently approved by the FDA for metastatic MTC (vandetanib, cabozantinib) come with toxicity and should be reserved for symptomatic/progressive disease. However, a large population of asymptomatic MTC patients has small tumor burden and/or disease that is more indolent. The standard management of these patients is observation. Preliminary data suggest that tumor growth measured by the rate of CEA and calcitonin increase can be quantified in a 3-6 months. Retrospective data from prostate cancer studies suggest vaccines can alter growth rates within 3-4 months. We hypothesize that GI-6207 can alter tumor growth rates in MTC and impact long-term outcome. Methods: A phase II study will evaluate the effect of GI-6207 onthe rates ofincrease in calcitonin in metastatic MTC. 34 patients with minimally symptomatic, radiographically evaluable, metastatic MTC will be randomized 1:1. Arm A will receive vaccine for a year from the time of enrollment. Arm B will receive vaccine after 6 months of surveillance. GI-6207 will be administered subcutaneously at 4 sites (10 yeast units/site), every 2 weeks for 3 months, then monthly up to 1 year. The primary endpoint will compare the effect of GI-6207 on calcitonin kinetics between the vaccine and surveillance arms in the first 6 months. Secondary endpoints include immunologic responses (including antigen-specific T cell responses), objective responses, time to progression, and changes in CEA kinetics. If this trial can prospectively demonstrate that vaccines can alter tumor growth rates, and if such changes are associated with clinical outcomes, then changes in tumor growth rates may become a clinical metric to evaluate vaccine efficacy in MTC and other populations.

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Battenberg, J. Friedrich. "Bayerisches Hauptstaatsarchiv. Reichskammergericht Band 15 Nr. 6207-6705." Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Germanistische Abteilung 128, no. 1 (August 1, 2011): 667. http://dx.doi.org/10.7767/zrgga.2011.128.1.667.

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Nikolic, Nevena, Sarah Kleinstein, Jelena Radenkovic, and Milan Kovacevic. "Abstract 6207: Exploring colorectal cancer with ARIA: Biomedical insights." Cancer Research 84, no. 6_Supplement (March 22, 2024): 6207. http://dx.doi.org/10.1158/1538-7445.am2024-6207.

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Abstract Gaining the promised benefits from the population-scale datasets, both clinical and genomic, is often hindered by the inability to easily access, explore and manipulate such complex data - a difficulty that ARIA was designed to overcome. In the field of biomedicine, organizations harness extensive datasets, gaining profound insights into patients and participants, thereby unleashing possibilities for accelerating research, especially in the realms of drug development and precision medicine. To facilitate navigation through the intricate landscape of biomedical data, Velsera has innovated ARIA to catalyse efficient and insightful analysis, with a keen emphasis on user-friendliness to ensure accessibility across a diverse professional audience. To demonstrate the practical application of ARIA, we explore genomic and clinical datasets to identify key differences in colorectal cancer progression. CRC, the third most common cancer globally, has unique characteristics in origination and progression from benign to pathogenic. Here we investigate differences between patients with polyps that do and do not progress to CRC, including key environmental factors such as smoking history, inactive lifestyle and obesity in conjunction with their known clinical and genetic risk factors. This exploration into the abilities of ARIA demonstrate the ability to analyse complex datasets combining both clinical and genomics data at a large scale. For the purpose of this demonstration, a Synthea Dataset, encompassing synthetic clinical and genomic data for 122,011 patients across various age groups, was utilized. This dataset was generated by Velsera specifically for testing ARIA functionalities. In conclusion, ARIA empowers efficient analysis of complex biomedical datasets, providing a comprehensive understanding of disease mechanisms and facilitating valuable insights. Citation Format: Nevena Nikolic, Sarah Kleinstein, Jelena Radenkovic, Milan Kovacevic. Exploring colorectal cancer with ARIA: Biomedical insights [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 6207.

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Naruse, H., S. Nagataki, H. Gomi, and H. Jinnai. "Revision of JIS A 6207 ^|^ldquo;Silica fume for use in concrete^|^rdquo;." Concrete Journal 49, no. 12 (2011): 12_10–12_16. http://dx.doi.org/10.3151/coj.49.12_10.

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Dressler, Robert, Hania Janek, Lauren Sager, David S. Kountz, and Judi Gravdal. "Learning Collaboratives in Medical Education: Exploring the Impact of Collaboratives’ Structure and Resources and Teams’ Experience." American Journal of Medical Quality 35, no. 4 (October 4, 2019): 297–305. http://dx.doi.org/10.1177/1062860619877941.

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The Alliance of Independent Academic Medical Centers (AIAMC) organized and coordinated a multicenter learning collaborative, National Initiative V (NI V), focused on community health and health inequity. A pre–post descriptive study was designed to examine the outcomes of the AIAMC NI V. Data were collected from pre- and post-assessment surveys as well as a project milestone self-assessment survey. Twenty-nine institutions participated. By the conclusion of the NI, the majority of institutions had completed at least 1 of the milestones in each of the pre-work/background (65.52%), measurement (62.07%), methods (62.07%), and implement/sustain (20.69%) domains. Institutions reported a significant association between their readiness assessments prior to the start of the NI compared with their status of activities on completion. Milestone achievement is significantly associated with 3 of the assessment items. Learning collaboratives with thoughtfully integrated structure and support can be impactful on topic readiness for the participating organizations.

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Bhandari, S. K., S. N. Hande, and M. Masoom Ali. "An Optimal Sequential Procedure for Ranking Pairwise Compared Treatments." Calcutta Statistical Association Bulletin 43, no. 3-4 (September 1993): 191–98. http://dx.doi.org/10.1177/0008068319930304.

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Scores of k players have been observed. Tho problem of selecting the player with highest expected wins is considered. An optimal sequential rule has been derived in this context, Its efficiency with the bost fixed sample size rule is considered at the common least favourable configuration. AMS 1980 Subject Classification: 62F07.

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Kalugina, L. V., T. F. Tatarchuk, and I. V. Shmulian. "Bacterial vaginosis. Modern view of the problem and its status in Ukraine." REPRODUCTIVE ENDOCRINOLOGY, no. 59 (July 22, 2021): 72–77. http://dx.doi.org/10.18370/2309-4117.2021.59.72-77.

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Research objective: to examine the incidence of asymptomatic and recurrent bacterial vaginosis (BV) in Ukrainian women and to evaluate diagnostic and treatment strategies for the disease control. Materials and methods. This study lasted from January to March 2021 and included 277 doctors of women's clinics, gynecological hospitals and oncology centers from all regions of Ukraine. Information was provided on 12 896 patients between of 18 and 59 ages with BV. Results. Analysis of data from 12 896 questionnaires allowed us to determine that women from 18 to 35 years of age (62.6%) were the most frequently consulted about BV. Only 58.72% patients with BV reported about abnormal vaginal discharge as the reason for visit, while 41.24% of the respondents reported other reasons. Questionnaire analysis of patients with vaginal discharge revealed scant symptoms of the disease: only 62.67% complained about the change of discharge character; 38.49% and 36.35% of examinees pointed to the vaginal itching and unpleasant odor, respectively; 19.89% of patients were troubled by dysuric symptoms and 15.10% of patients mentioned dyspareunia. In the list of submitted questionnaires, 59.92% of patients indicated an additional examination to identify the causes of vaginitis by the PCR method (urogenital scraping). According to its results, Gardnerella vaginalis was detected in diagnostically significant concentrations in 71.49% of patients, Atopobium vaginae was found in 11.32% of cases, Mobiluncus spp. was detected in 19.96% of patients and Trichomonas vaginalis was found in 13.12% of patients. Candida colonization was diagnosed in 62.07%, with Candida albicans in 48,52% cases and non-albicans forms in 13,55% of patients.In the treatment of BV priority was given to the vaginal forms of the most compliant therapy regimens: 2 times a day for 3 days or once a day for 7 days, depending on the clinical situation. Some patients opted for a long course of treatment for recurrent infections, choosing the combination metronidazole 750 mg / miconazole 200 mg 1 suppository once a day for 5 days for 12 months.Conclusion. Diagnosis of BV in Ukraine continues to be based on clinical conditions and requires a unified algorithm that will be based on current clinical guidelines and dictated by national protocols for management. High mycotic colonization (62,07%) in BV makes it expedient to use combined agents (metronidazole 750 mg / miconazole 200 mg tioconazole/tinidazole) both as etiotropic and empirical therapy and especially if there are clinical conditions that may can cause BV (before surgical interventions, after antibiotic therapy, in endocrine pathology, etc.).

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Любченко, М. Ю., Ж. Б. Бибекова, and К. В. Заровный. "Anxiety and Depression Comorbidities in Irritable Bowel Syndrome." Психиатрия, психотерапия и клиническая психология, no. 3 (November 21, 2022): 293–99. http://dx.doi.org/10.34883/pi.2022.13.3.002.

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Синдром раздраженного кишечника (СРК) является хроническим заболеванием, которое характеризуется болью в животе и изменениями стула при отсутствии органических изменений слизистой кишечника. При этом часто встречаются сопутствующие (коморбидные) психические состояния (расстройства невротического уровня), однако неясно, предшествуют ли они симптомам или обусловлены ими. Целью нашего исследования было выяснить различия по выраженности тревоги и/или депрессии (при их наличии) у пациентов с разными типами СРК. В группу исследования вошли 93 пациента (средний возраст (38±11) лет; женщин – 67, мужчин – 26) с диагнозом СРК. Все они ответили на структурированную анкету с демографическими и клиническими данными. Тревога и депрессия оценивались по шкале оценки тревожности Гамильтона (HAM-A) и шкале депрессии Гамильтона (HAM-D). Распределение подтипов СРК было следующим: СРК с диареей (СРК-Д) 47%, СРК с запорами (СРК-З) 29%, СРК смешанного типа (СРК-См) 24%. Тревога и/или депрессия были обнаружены у 62,36%. Сравнение между подгруппами показало, что у пациентов с СРК-Д чаще регистрировалась тревога (62,07%), у пациентов с СРК-З – депрессия (90,48%). Более высокие показатели по шкале тревоги выявлены у пациентов с СРК-См (23±2,9). Эти особенности следует учитывать при клиническом ведении указанных подгрупп пациентов. Irritable bowel syndrome (IBS) is a chronic disease characterized by abdominal pain and changes in stool in the absence of organic changes in the intestinal mucosa. At the same time, concomitant (comorbid) mental conditions (neurotic disorders) are common, but it is unclear whether they precede the symptoms or are caused by them. The aim of our study was to find out the differences in the severity of anxiety and / or depression (if any) in patients with different types of IBS. The study group included 93 patients (mean age (38±11) years; a total of 67 women and 26 men) diagnosed with IBS. They all completed a structured questionnaire with demographic and clinical data. Anxiety and depression were assessed using the Hamilton Anxiety Rating Scale (HAM-A) and the Hamilton Depression Scale (HAM-D). The distribution of IBS subtypes was as follows: IBS with diarrhea (IBS-D) 47%, IBS with constipation (IBS-C) 29%, mixed IBS (IBS-М) 24%. Anxiety and/or depression were found in 62.36%. Comparison between the subgroups revealed that patients with IBS-D were more likely to have anxiety (62.07%), and patients with IBS-C had depression (90.48%). Higher indicators on the anxiety scale were found in patients with IBS-М (23±2.9). These features should be taken into account in the clinical management of these patient subgroups.

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Cafici, VD, ND Margulies, AB Wojakowski, J. M. Sánchez, F. Collia, and M. Panal. "OGP 6207 Severe osteogenesis imperfecta with non-inmune hydrops. Case report." Ultrasound in Medicine & Biology 23 (January 1997): S124. http://dx.doi.org/10.1016/s0301-5629(97)80770-3.

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15

Odongo, L. O., and M. Samanta. "On Estimation of a Functional of a Probability Density Function." Calcutta Statistical Association Bulletin 43, no. 1-2 (March 1993): 13–24. http://dx.doi.org/10.1177/0008068319930102.

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The problem of estimating the integral of the square of a probability density function is considered, It is shown that under some regularity conditions the kernel estimate of this functional is asymptotically normally distributed. An expression for the smoothing parameter that minimizes the mean square error of the estimate is derived. Results of simulation studies are included. AMS (1980) Subject Classification: Primary 62G07 Secondary 60FOS.

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Li, Xin, Hao Zhou, Fei Qi, Xiangheng Niu, Xuechao Xu, Fengxian Qiu, Yanfang He, Jianming Pan, and Liang Ni. "Correction: Three hidden talents in one framework: a terephthalic acid-coordinated cupric metal–organic framework with cascade cysteine oxidase- and peroxidase-mimicking activities and stimulus-responsive fluorescence for cysteine sensing." Journal of Materials Chemistry B 7, no. 15 (2019): 2565. http://dx.doi.org/10.1039/c9tb90044f.

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Correction for ‘Three hidden talents in one framework: a terephthalic acid-coordinated cupric metal–organic framework with cascade cysteine oxidase- and peroxidase-mimicking activities and stimulus-responsive fluorescence for cysteine sensing’ by Xin Li et al., J. Mater. Chem. B, 2018, 6, 6207–6211.

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YUFITA, ROLINA. "UPAYA MENINGKATKAN KEAKTIFAN DAN HASIL BELAJAR PENDIDIKAN AGAMA HINDU DAN BUDI PEKERTI MATERI CATUR WARNA DALAM KEHIDUPAN MODEL PEMBELAJARAN CTL (CONTEXTUAL TEACHING AND LEARNING) SISWA KELAS X SMAN 2 KASONGAN." PAEDAGOGY : Jurnal Ilmu Pendidikan dan Psikologi 3, no. 2 (November 26, 2023): 156–62. http://dx.doi.org/10.51878/paedagogy.v3i2.2557.

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This research aims to increase the activeness and learning outcomes of Hindu religious education and character in color chess material in the life of the CTL (Contextual Teaching And Learning) learning model for class X SMAN 2 Kasongan students. This research is classroom action research with the application of Contextual Teaching and Learning. The subjects of this research were 6 Hindu students at SMAN-2 Kasongan class X. Data collection techniques use observation sheets, documentation and test results. Based on the actions that have been taken, implementing the CTL (Contextual Teaching and Learning) learning model can increase student activity in learning activities. This can be proven that learning activity has increased from the initial condition of 11 students or 37.93%, in cycle I there were 19 students or 65.52%, and in cycle II there were 27 students or 93.10%. Student learning outcomes in the initial study were only 62.07 to 67.93 and 82.76 in the second cycle, with a learning completeness level of 9 students or 31.03%, in the first cycle there were 14 students or 48.28%, and in the second cycle there were 25 students or 86.21%, although there were still 4 students (13.79%) who had not completed it, but because all the criteria for the success of the learning process had been achieved in the second cycle, it was stated that the learning improvement process was complete and successful in the second cycle. ABSTRAKPenelitian ini bertujuan untuk meningkatkan keaktifan dan hasil belajar pendidikan agama hindu dan budi pekerti materi catur warna dalam kehidupan model pembelajaran CTL (Contextual Teaching And Learning) siswa kelas X SMAN 2 kasongan. Penelitian ini merupakan penelitian tindakan kelas dengan penerapan Contextual Teaching and Learning. Subjek penelitian ini adalah siswa-siswi Agama Hindu SMAN-2 Kasongan kelas X sebanyak 6 siswa. Teknik pengumpulan data menggunakan lembar observasi, dokumentasi, dan hasil tes. Berdasarkan tindakan yang telah dilakukan penerapan model pembelajaran CTL (Contextual Teaching and Learning) dapat meningkatkan aktivitas siswa pada kegiatan pembelajaran. Hal ini dapat dibuktikan bahwa keaktifan belajar mengalami peningkatan dari kondisi awal sebanyak 11 siswa atau 37,93%, siklus I ada 19 siswa atau 65,52%, dan pada siklus II ada 27 siswa atau 93,10%. Hasil belajar siswa pada studi awal hanya 62,07 menjadi 67,93 dan 82,76 pada siklus kedua, dengan tingkat ketuntasan belajar sebanyak 9 siswa atau 31,03%, siklus I ada 14 siswa atau 48,28%, dan pada siklus II ada 25 siswa atau 86,21%, walaupun masih ada 4 siswa (13,79%) yang belum tuntas namun karena semua kriteria keberhasilan proses pembelajaran telah tercapai pada siklus kedua maka dinyatakan bahwa proses perbaikan pembelajaran selesai dan berhasil pada siklus kedua.

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Meneses Urrea, Luz Adriana, Estela Rodríguez Torres, and Mayerlin Otero Ortiz. "Signos de vida en la morbilidad de la gestante." Enfermería Global 20, no. 1 (January 1, 2021): 341–62. http://dx.doi.org/10.6018/eglobal.425571.

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Para la valoración de las gestantes es indispensable incorporar parámetros que permitan la identificación de alteraciones de parte del personal de enfermería y medicina. Esta valoración en la atención de salud no se realiza en todas las instituciones en las cuales consultan las gestantes, llevarlo a cabo permite detectar a tiempo las alteraciones clínicas que incrementan la morbilidad y la mortalidad materna. El estudio determina las alteraciones en gestantes cuando se aplica la Escala de Alerta Temprana en una institución de alta complejidad en Colombia.Método: Investigación observacional descriptiva, en 308 gestantes con más de un día de encontrarse en hospitalización y unidad de cuidados especial obstétrico, recolectando información contenida en las historias clínicas digitales y las evaluaciones realizadas por el personal de salud durante el periodo enero a diciembre del 2017, a través de un formato general de condiciones de salud y la escala de alerta temprana en una institución de alta complejidad.Resultados: La edad de las gestantes se encuentra entre 14 y 45 años. El diagnóstico más frecuente de ingreso fue preclampsia con un 38.2% IC95% (32.62-43.98). La mayor frecuencia de alteraciones está en la tensión arterial sistólica con un 70.1% IC95% (50.75-62.07), tensión diastólica 56.5% IC 95% (50.75-62.07) y alteración respiratoria 28.9% IC (23.97-34.36). Se encontró significancia estadística entre la estancia y los antecedentes patológicos con p<0.03. Los procedimientos de valoración, diagnóstico y registro oportuno por el personal de enfermería y médico son de vital importancia en la detección precoz de la morbilidad materna extrema. For the assessment of pregnant women, it is essential for nursing and medical staff to incorporate parameters to identify alterations in antenatal health status. This health care assessment is not performed by all institutions that provide antenatal care to pregnant women. Performing antenatal health care assessment assists in the early detection of clinical alterations that can increase morbidity and maternal mortality. The study aims to determine the alterations in pregnant women with the application of the Early Warning Scale in a highly complex institution in Colombia.Method: This research is observational, descriptive, and was carried out on 308 pregnant women who were hospitalized or admitted in a Special Obstetric Care Unit (SOCU) for more than one day in a highly complex institution. Data contained in digital medical records were collected and evaluations were carried out by healthcare staff between January 2017 and December 2017, by way of an overall format for health conditions and the Early Warning Scale.Results: The age of pregnant women ranged between 14 and 45 years. The most common diagnosis for admission was preeclampsia with 38.2% CI 95% (32.62–43.98). The highest frequency of alterations was found in systolic blood pressure with 70.1% Confidence Interval (CI) 95% (50.75–62.07), diastolic blood pressure 56.5% CI 95%(50.75–62.07), and respiratory distress 28.9% CI (23.97–34.36). Statistical significance was found between hospital stay and pathological history with p < 0.03. Timely assessment, diagnosis, and registration procedures by nurses and medical staff are of vital importance in the early detection of extreme maternal morbidity.

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Palupi, Erni, and Firosalia Kristin. "IMPROVEMENT OF SPEAKING SKILLS THROUGH THE APPLICATION OF TALKING STICK MODEL IN FIFTH GRADE STUDENTS OF KUTOWINANGUN 04 ELEMENTARY SCHOOL." Jurnal Handayani 10, no. 1 (July 23, 2019): 35. http://dx.doi.org/10.24114/jh.v10i1.14136.

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Abstract: Improvement Of Speaking Skills Through The Application Of Talking Stick Model In Fifth Grade Students Of Kutowinangun 04 Elementary School. This study aims to improve speaking skills through the application of the Talking Stick model in fifth grade students of Kutowinangun 04 Elementary School. This type of research is Classroom Action Research (PTK) with research subjects in fifth grade students of Kutowinangun 04 Elementary School consisting of 18 male students and 11 female students. The data collection technique used is observation. The procedure of action research consists of two cycles. Each cycle through four stages of research includes: planning, action, observation, and reflection. The data analysis technique used quantitative descriptive and qualitative descriptive. The results showed an increase in the percentage of the average value of students' speaking skills by category in the first cycle, which was equal to 11.56%, with the initial conditions 58.10% (categories need guidance) increased to 69.66% (sufficient category). In the second cycle, an increase of 15.34%, with an initial condition of 69.66% (sufficient category) increased to 85% (good category). The percentage of completeness of speaking skills showed that in pre-action as many as 5 students completed (17.24%), increased to 18 students completed (62.07%) in the first cycle, and increased to 29 students completed (100%) in cycle II. Thus, through the application of the Talking Stick model can improve the learning skills of fifth grade students of Kutowinangun 04 Elementary School. Keywords: Improving Student Speaking Skills, Talking Stick Model Abstrak: Peningkatan Keterampilan Berbicara Melalui Penerapan Model Pembelajaran Talking Stick Pada Siswa Kelas 5 SD Ktowinangun 04. Penelitian ini bertujuan untuk meningkatkan keterampilan berbicara melalui penerapan model pembelajaran Talking Stick pada siswa Kelas 5 SD Negeri Kutowinangun 04 Salatiga. Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK) dengan subjek penelitian siswa kelas 5 SD Negeri Kutowinangun 04 yang terdiri dari 18 siswa laki-laki dan 11 siswa perempuan. Teknik pengumpulan data yang digunakan adalah observasi. Prosedur penelitian tindakan terdiri dari dua siklus. Setiap siklus melalui empat tahap penelitian diantaranya: perencanaan, tindakan, observasi, dan refleksi. Teknik analisis data yang digunakan berupa deskriptif kuantitatif dan deskriptif kualitatif. Hasil penelitian menunjukkan terjadi peningkatan persentase nilai rata-rata keterampilan berbicara siswa berdasarkan kategori pada siklus I, yaitu sebesar 11,56%, dengan kondisi awal 58,10% (kategori perlu bimbingan) meningkat menjadi 69,66% (kategori cukup). Pada siklus II, terjadi peningkatan sebesar 15,34%, dengan kondisi awal 69,66% (kategori cukup) meningkat menjadi 85% (kategori baik). Persentase ketuntasan keterampilan berbicara menunjukkan bahwa pada pratindakan sebanyak 5 siswa tuntas (17,24%), meningkat menjadi 18 siswa tuntas (62,07%) pada siklus I, dan meningkat menjadi 29 siswa tuntas (100%) pada siklus II. Dengan demikian, melalui penerapan model pembelajaran Talking Stick dapat meningkatkan keterampilan belajar siswa kelas 5 SD Kutowinangun 04. Kata Kunci: Peningkatan Keterampilan Berbicara Siswa, Model Pembelajaran Talking Stick

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Hidayati, Ika Septi. "UPAYA MENINGKATKAN MINAT BELAJAR MATEMATIKA DENGAN METODE COOPERATIVE SCRIPT." Intersections 5, no. 1 (February 1, 2020): 1–8. http://dx.doi.org/10.47200/intersections.v5i1.509.

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The purpose of this study was to determine the appropriate application of the cooperative script method in order to increase the learning interest of the fifth grade students of SD Negeri Prembulan. The results of this study indicate that: (1) In general, the application of the appropriate cooperative script method is effective in increasing interest in learning mathematics, (2) Increasing interest in learning mathematics for fifth grade students of SD Prembulan in pre-cycle by 62.07 in cycle I of 76, 31 in cycle II amounted to 85.39.

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Dewangan, Ritesh Kumar, and Surendra Pal Singh Matharu. "Analysis of Elliptical Contact area of Rolling Element Bearing 6207 using Artificial Neural Network." Indian Journal of Science and Technology 10, no. 5 (February 1, 2017): 1–5. http://dx.doi.org/10.17485/ijst/2017/v10i5/99555.

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Syage, Jack A., and John E. Wessel. "Erratum: Antiresonance in autoionizing Rydberg series of naphthalene [J. Chem. Phys. 87, 6207 (1987)]." Journal of Chemical Physics 88, no. 6 (March 15, 1988): 4103. http://dx.doi.org/10.1063/1.454768.

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Hubbard, John W., Thomas H. Hintze, Jeffrey T. Shapiro, Gabor Kaley, Ronald D. Smith, and Peter S. Wolf. "Comparative hypotensive activity of REV 6207 and enalapril in the conscious furosemide-treated monkey." Drug Development Research 17, no. 1 (1989): 17–21. http://dx.doi.org/10.1002/ddr.430170103.

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Dewantari, Nustin Merdiana. "Postur Kerja Pemilah Sampah Anorganik Di TPST XYZ." Journal Industrial Servicess 6, no. 2 (March 31, 2021): 122. http://dx.doi.org/10.36055/62007.

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Yang, Lina, Hongyun Zhang, Jinghang Huang, Yafan Zhao, Danshi Zhu, and He Liu. "Optimization of ultrasonic-assisted extraction of inulin from Jerusalem artichoke." E3S Web of Conferences 78 (2019): 02007. http://dx.doi.org/10.1051/e3sconf/20197802007.

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An efficient ultrasonic-assisted extraction of inulin from Jerusalem artichoke was investigated by Response Surface Methodology (RSM). The results showed that the yield of ultrasonic-assisted extraction was 62.07 ± 0.39% over the microwave (40.85 ± 0.28%) and hot water extraction (27.42 ± 0.42%). The Box-Behnken Design (BBD) was used to optimize the effects of three parameters (temperature-X1, ultrasonic power-X2 and time-X3) on inulin yield. Analysis of variance showed that the contributions of X1, X3, X12, X13, X22 were significant. The optimal yield of inulin was 82.93 ± 1.03% at 82 °, 120 W and 18 min.

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Brocklehurst, Adam, and Mauricio Suárez. "Ian Percival, Quantum State Diffusion. Cambridge University Press: Cambridge, 1999, cloth £30.00. ISBN: 0 521 62007 4." British Journal for the Philosophy of Science 51, no. 3 (September 1, 2000): 527–30. http://dx.doi.org/10.1093/bjps/51.3.527.

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Takashima, T., C. Wu, M. Takashima-Hirano, Y. Katayama, Y. Wada, M. Suzuki, H. Kusuhara, Y. Sugiyama, and Y. Watanabe. "Evaluation of Breast Cancer Resistance Protein Function in Hepatobiliary and Renal Excretion Using PET with 11C-SC-62807." Journal of Nuclear Medicine 54, no. 2 (January 3, 2013): 267–76. http://dx.doi.org/10.2967/jnumed.112.110254.

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Hsu, Tong—An. "Some Optimal Selection Procedures for Dependent Normal Populations." Calcutta Statistical Association Bulletin 42, no. 1-2 (March 1992): 19–28. http://dx.doi.org/10.1177/0008068319920102.

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We consider k dependent normal populations having known equal variance. The problem is to select the population associated with the largest mean. Let π1, ..., πk be k populations. We assume that the random variable Xi associated with πi ( i = 1, ..., k). Let X1, ..., Xk be k—variate normal distribution with unknown mean μ1, ... , μk and with equal variance σ2 and with correlation matrix { ρi j} For two case : (a) ρi j = aiaj for i ≠ j and (b) ρi j = ρ, for i ≠ j, we construct some optimal subset selection procedure to select a subset of the k dependent normal population containing the largest population mean. AMS ( 1980) subject classification : Primary 62F07 ; Secondary 62030

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Sesweti. "Penerapan Pendekatan RME (Realistic Mathematics Education) Berbasis Google Classroom Guna Meningkatkan Minat dan Hasil Belajar Siswa." Journal of Education Informatic Technology and Science 5, no. 1 (April 13, 2023): 11–20. http://dx.doi.org/10.37859/jeits.v5i1.4765.

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Penelitian ini bertujuan untuk meningkatkan minat belajar siswa melalui penerapan pendekatan RME (Realistic Mathematics Education) berbasis Google Classroom. Subjek penelitian adalah sisiwa kelas Kelas XII AK1 SMKN 1 yang berjumlah 29 orang. Hasil penelitian adalah 1) Penerapan pendekatan RME (Realistic Mathematics Education) berbasis Google Classroom, dan memanfaatkan fitur-fitur yang ada didalamnya maka minat belajar siswa menjadi lebih baik. 2) Penerapan pendekatan RME dapat Meningkatkan Minat Belajar Siswa Kelas XII AK1 SMKN 1 Benai. Pada siklus I siswa dengan kategori berminat berjumlah 34.48% menjadi 62.07 % pada siklus II. 3) Penerapan pendekatan RME dapat Meningkatkan hasil belajar siswa kelas XII AK1 SMKN 1 Benai, pada siklus I siswa yang mencapai KKM berjumlah 55.2% dan pada siklus II meningkat menjadi 82.8%.

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Brizot, Maria L., Denise A. L. Pedreira, Cláudia H. Chiba, Nádia E. V. Reis, Seizo Miyadahira, and Marcelo Zugaib. "OGO 6207 Ultrasound scan in the detection of fetal malformations at 10 to 14 weeks' gestation." Ultrasound in Medicine & Biology 23 (January 1997): S104. http://dx.doi.org/10.1016/s0301-5629(97)80688-6.

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Dewangan, Ritesh Kumar, and Surendra Pal Singh Matharu. "Evaluation of Lubricant Film Thickness for Ball Bearings 6207 & 6307 with Elliptical & Circular Contact Area." International Journal of Engineering and Technology 9, no. 1 (February 28, 2017): 208–16. http://dx.doi.org/10.21817/ijet/2017/v9i1/170901422.

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Murdaningrum, Mas Indah. "Peningkatan Keaktifan dan Hasil Belajar Ekonomi dengan Model Pembelajaran Kooperatif Tipe Make A Match Pada Peserta Didik Kelas X IPS 3 MAN 2 Bantul." Jurnal Edutrained : Jurnal Pendidikan dan Pelatihan 5, no. 2 (December 20, 2021): 124–39. http://dx.doi.org/10.37730/edutrained.v5i2.146.

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Penelitian ini bertujuan meningkatkan keaktifan dan hasil belajar ekonomi peserta didik dengan Model Pembelajaran Kooperatif Tipe Make A Match di MAN 2 Bantul. Subjek penelitian adalah peserta didik kelas X IPS 3 MAN 2 Bantul berjumlah 29 orang. Teknik pengumpulan data menggunakan observasi dan tes. Teknik analisis data menggunakan deskriptif kuantitatif. Hasil penelitian menunjukkan bahwa pembelajaran dengan menggunakan model kooperatif tipe Make A Match dapat meningkatkan keaktifan dan hasil belajar peserta didik. Hal ini dibuktikan dengan peningkatan keaktifan belajar ekonomi pada siklus I, peserta didik yang mempunyai keaktifan belajar kategori minimal sedang sebesar 62,64%, pada siklus II meningkat menjadi 77,58%. Peningkatan hasil belajar peserta didik dilihat dari rerata kelas siklus I ke siklus II mengalami kenaikan. Peserta didik yang mengalami tuntas belajar pada siklus I sebesar 62,07%, dan meningkat pada siklus II sebesar 86,21%.

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Kumar, Narinder, Amar Nath Gill, and Gobind P. Mehta. "Selection Procedures for Location Parameters Based on Two-Sample U-Statistics." Calcutta Statistical Association Bulletin 42, no. 3-4 (September 1992): 201–20. http://dx.doi.org/10.1177/0008068319920305.

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Let π1, ... , πk be k independent populations and let Fi ( x)= F( x - θi) be the absolutely continuous cumulative distribution function (cdf) of the i-th population indexed by the location parameter θi; i=1,,.... k. A class of subset selection procedures based on sub-sample extrema for unequal sample sizes is proposed for the problem of selecting a subset from ( π1, .... πk) which contains the population with largest location parameter. The proposed subset selection procedures are then compared with the subset selection procedures of Hsu (1981) in the sense of Pitman ARE (asymptotic relative efficiency). It is shown that these procedures can approximately be implemented with the help of existing tables and sample size sufficient for their implementation, based on simulation results, is discussed. AMS (1980) Subject Classification: Primary 62F07; Secondary 62H10

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Setyadi, Iwan, Suryadi Suryadi, Kirman Kirman, and Mirza Wibisono. "PENGARUH PROSES HOT ROLLING DAN KANDUNGAN CERIUM PADA DAYA HANTAR LISTRIK PADUAN AlZrCe SEBAGAI MATRIK KOMPOSIT BERPENGUAT Al2O3." Majalah Ilmiah Pengkajian Industri 10, no. 3 (December 18, 2016): 189–94. http://dx.doi.org/10.29122/mipi.v10i3.483.

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Sebagai upaya untuk mendapatkan material konduktor listrik, paduan Alumunium-Cerium merupakan salah satu alternatif material yang dikembangkan sebagai paduan dasar untuk komposit bermatrik logam. Dalam manufaktur kawat konduktor, proses pengerolan panas merupakan bagian proses yang tidak terpisahkan untuk mereduksi penampang.Adapun fokus penelitian adalah mengamati pengaruh pengerolan panas terhadap paduan AlZrCe, dimana yang divariasikan adalah prosentase reduksi dan kandungan cerium dalam paduan.Hasil penelitian menunjukkanÂ bahwa peningkatan prosentasi reduksi pengerolan panas dan kenaikan kandungan Cerium dalam paduan AlZrCeÂ memberikan dampak peningkatan nilai konduktivitas listrik paduan AlZrCe. Hasil optimal yang diperoleh adalah 62,07% IACS, yang didapat dariÂ master paduan AlZrCe dengan kandungan 0,3% Ce dan reduksi sebesar 67,5%. Hasil ini mendekati bahan EC (99,6% Al) yang memiliki konduktivitas listrik 63,4% IACS.Â Kata kunci : Â paduan AlZrCe, pengerolan panas, prosentase reduksi,kandungan Cerium, koduktivitas listrik, IACS.

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Furquim, Fabiana Cristina, Cristina Eunice Okuyama, Sandro Rostelato-Ferreira, Carla Leticia Rivero-Wendt, Helder Oliveira, and Susana Nogueira Diniz. "Incidência de Interações Medicamentosas e Avaliação Clínica nos Pacientes de um Hospital Público Brasileiro." Ensaios e Ciência C Biológicas Agrárias e da Saúde 24, no. 3 (October 26, 2020): 202–10. http://dx.doi.org/10.17921/1415-6938.2020v24n3p202-210.

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Interações droga-droga (IDDs) são responsáveis por problemas terapêuticos e as principais causas de reações adversas a medicamentos que levam a hospitalização. O objetivo do trabalho foi analisar a incidência de IDDs em pacientes admitidos em hospital público no Brasil, em 2015. Em um estudo transversal, 351pacientes foram selecionados com IDDs utilizando-se o banco de dados da Micromedex®, e as interações foram classificadas de acordo com a severidade e documentação. Os potenciais IDDs foram avaliados durante o acompanhamento farmacoterapêutico diário por anamnese farmacêutica e a análise dos exames laboratoriais foi realizada. Um total de 2.937 potenciais IDDs foram identificados e 28,42% deles tinham sinais e sintomas clínicos confirmados em 87 pacientes (29%). Entre os pacientes que apresentaram interações, 62,07% tinham mais que 60 anos. Neste grupo de idade, 61,27% de todos os sinais e sintomas clínicos observados foram também identificados, demonstrando uma associação positiva entre interações clínicas e idade. Além disso, uma correlação positiva entre o número de drogas prescritas e a ocorrência de sinais clínicos também foram observados. Muitos IDDs observados foram de severidade moderada e estavam relacionados a alterações das pressões arteriais e níveis glicêmicos. Este estudo demonstrou que IDDs estão diretamente relacionados a idade e número de drogas prescritas. E a grande frequência de IDDs com documentação fraca alertam para a necessidade de se analisar esse tipo de interação. Sendo assim, este estudo mostrou que potenciais IDDs e sinais e sintomas clínicos significantes em pacientes só reforçam a necessidade de se apoiar a farmácia clínica. Palavras-chave: Interação Droga-Droga (IDD). Pacientes Internados. Farmacoterapia, Poli Farmácia. Sinais e Sintomas. Abstract Drug-drug interactions (DDIs) are responsible for therapeutic problems and the main causes of adverse drug reactions that require hospitalization. The aim of this study was to analyze the incidence of DDIs in patients admitted in a Public Hospital in Brazil, in 2015. In a cross-sectional study, DDIs were screened in 351 patients, using Micromedex® database, that classify interactions according to severity and documentary evidence. Potential DDIs were assessed at the daily pharmacotherapeutic follow-up through pharmaceutical anamnesis and analysis of laboratory tests were performed. A total of 2,937 potential DDIs were identified and 28.42% of these had confirmed signs and symptoms clinical in 87 patients (29%). Among the patients that presented interactions, 62.07% were older than 60 years. In this age group, 61.27% of all signs and symptoms clinical observed in the study were also identified, demonstrating a positive association between the occurrence of clinical interactions and age. In addition, a positive correlation between the number of drugs prescribed and the occurrence of signs clinicals was also observed. Most DDIs observed were of moderate severity and were related to imbalance of blood pressure and glycemic levels. This study demonstrated that DDIs are directly related to the age and number of drugs prescribed. And the greater frequency of DDIs with fair documentary evidence alerts to the need to consider all the possible interactions. Thereafter, this study showed that potential DDIs and sign and clinical symptoms are significant in patients and reinforce the need to support Clinical Pharmacy. Keywords: Drug-Drug Interaction (DDI). Inpatients. Pharmacotherapy. Poly Pharmacy. Sign and Symptom.

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Lenggogeni, Lenggogeni. "Evaluasi Program Praktik Kerja Lapangan Program Studi D3 Teknologi Konstruksi Bangunan Gedung Fakultas Teknik Universitas Negeri Jakarta." Jurnal PenSil 9, no. 2 (May 7, 2020): 61–67. http://dx.doi.org/10.21009/jpensil.v9i2.14568.

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Penelitian ini bertujuan untuk mengetahui kesesuaian implementasi program magang di Program Studi Diploma Teknologi Konstruksi Bangunan, Fakultas Teknik, Universitas Negeri Jakarta, termasuk 1) perencanaan, 2) implementasi dan 3) hasil tes praktik siswa dengan standar objektif. Penelitian ini juga bertujuan untuk mengetahui hambatan-hambatan yang dialami oleh siswa dalam pelaksanaan magang dan mencari tahu hal-hal yang mendukung pelaksanaan program. Metode yang digunakan dalam penelitian ini adalah model evaluasi Countenance Stake. Model ini mencakup evaluasi Anteseden, Transaksi, dan Output. Data dalam penelitian ini berasal dari kurikulum, administrasi, dan responden siswa yang mengambil magang pada 2018/2019. Berdasarkan hasil evaluasi, program memenuhi aspek perencanaan dan implementasi yang memenuhi standar. Pada tahap evaluasi, 62,07% siswa menerima nilai kumulatif A-. Dari jumlah ini, para peserta dapat memahami semua materi dengan 81% hingga 85%. Skor umpan balik adalah 4, yaitu, siswa memahami kompetensi spesifik yang diperoleh selama magang.

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Bilusic, Marijo, Christopher R. Heery, Philip M. Arlen, Myrna Rauckhorst, David Apelian, Kwong Y. Tsang, Jo A. Tucker, et al. "Phase I trial of a recombinant yeast-CEA vaccine (GI-6207) in adults with metastatic CEA-expressing carcinoma." Cancer Immunology, Immunotherapy 63, no. 3 (December 7, 2013): 225–34. http://dx.doi.org/10.1007/s00262-013-1505-8.

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Hendriati, Hendriati. "LASERASI KANALIS LAKRIMALIS PADA LUKA ROBEK PALPEBRA DI RS. Dr. M. DJAMIL PADANG." Majalah Kedokteran Andalas 34, no. 2 (May 2, 2015): 112. http://dx.doi.org/10.22338/mka.v34.i2.p112-120.2010.

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AbstrakMenentukan Epidemiologi laserasi kanalis lakrimalis pada luka robek palpebra di Rumah Sakit Dr. M. Djamil Padang.Studi Retrospektif mengenai laserasi kanalis lakrimalis pada luka robek palpebra di Rumah Sakit Dr. M. Djamil dari bulan Juli 2006 - Juni 2009. Data dikumpulkan dari Rekam Medik.Ada 29 orang pasien yang didiagnosa laserasi kanalis lakrimalis dari 229 kasus luka robek palpebra (12,66%), 23 orang pasien (79,31%) adalah laki-laki dan 6 orang lagi perempuan (20,69%). Berdasarkan usia, laserasi kanalis lakrimalis paling banyak terjadi pada pasien berusia 41-50 tahun (27,58%), paling sering terjadi di kanalis lakrimalis inferior, yaitu 18 kasus dari 29 (62.07%). Berdasarkan lokasi kejadian, yang terbanyak adalah karena kecelakaan di jalan raya, yaitu sebanyak 16 dari 29 kasus (55.18%). Berdasarkan penyebabnya, yang terbanyak adalah trauma tumpul. Sebanyak 23 dari 29 kasus tersebut dilakukan tindakan kanalisasi (79,31%).Trauma tumpul merupakan penyebab terbanyak laserasi kanalis lakrimalis, kanalikulus inferior lebih sering terjadi dari pada superior. Laki-laki lebih banyak dikenai dari pada perempuan, dan terbanyak di kelompok usia 41-50 tahun.Kata kunci : laserasi kanalis lakrimalis, luka robek palpebraAbstractTo determine the epidemiology of canalicular lacerations on eyelid injury at Dr. M. Djamil hospital.A retrospective study of canalicular lacerations on eyelid injury in Dr. M. Djamil Hospital between July 2006 - June 2009. Data were colleted from medical record.There were 29 patient with diagnosis canalicular lacerations of 229 eyelid injury (12.66%), twenty three patients (79.31%) were males and 6 were females (20.69%). Based on the age, canalicular lacerations was mostly found in the patient with aged 41-50 y o (27.58%), canalicular lacerations was mostly present in lower canaliculi, with the frequency of 18 cases out of 29 cases (62.07%). Based on place of injury, most of the patient get injury at high way, about 16 cases out of 29 cases (55.18%). Based on source of injury, the most source of injury were blunt objects, canalization was the most common therapy 23 cases out of 29 cases (79.31%).ARTIKEL PENELITIAN113Blunt injury was the most common source of canalicular lacerations, the lower was more than upper. Male was more than Female, and mostly was found on age 41-50.Key word : canalicular laceration, eyelid injury

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Koshti, Rohan D., and Kirtee K. Kamalja. "Efficient Estimation of a Scale Parameter of Bivariate Lomax Distribution by Ranked Set Sampling." Calcutta Statistical Association Bulletin 73, no. 1 (April 11, 2021): 24–44. http://dx.doi.org/10.1177/0008068321992520.

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Ranked set sampling (RSS) is an efficient technique for estimating parameters and is applicable whenever ranking on a set of sampling units can be done easily by a judgment method or based on an auxiliary variable. In this paper, we assume [Formula: see text]to have bivariate Lomax distribution where a study variable [Formula: see text]is difficult and/or expensive to measure and is correlated with an auxiliary variable [Formula: see text] which is readily measurable. The auxiliary variable is used to rank the sampling units. In this article, we propose an estimator for the scale parameter of bivariate Lomax distribution using some of the modified RSS schemes. Efficiency comparison of the proposed estimators is performed numerically as well as graphically. A simulation study is also performed to demonstrate the performance of the proposed estimators. Finally, we implement the results to real-life datasets. AMS classification codes: 62D05, 62F07, 62G30

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Asriani, Asriani, Miftakhur Rohmah, and Sigit Priyono. "PENGARUH PENERAPAN METODE SPONTANEOUS GROUP DISCUSSION (SGD) TERHADAP HASIL BELAJAR MATA PELAJARAN EKONOMI BISNIS PADA PESERTA DIDIK KELAS X TINGKAT SMK DI BUAY PEMUKA BANGSA RAJA." UTILITY: Jurnal Ilmiah Pendidikan dan Ekonomi 4, no. 1 (February 20, 2020): 44–55. http://dx.doi.org/10.30599/utility.v4i1.628.

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Penelitian ini betujuan untuk mengetahui penerapan metode Spontaneous Group Discussion (SGD) terhadap hasil belajar mata pelajaran Ekonomi Bisnis peserta didik kelas X SMK. penelitian eksperimen dengan desain postest control group design. Pengumpulan data menggunakan tes dan dokumentasi, analisis data menggunakan uji t polled varians. Hasil penelitian yang diperoleh untuk penerapan metode Spontaneous Group Discussion (SGD) pada pembelajaran Ekonomi Bisnis di kelas X SMK dikategorikan. Hasil belajar mata pelajaran Ekonomi Bisnis peserta didik dengan menerapkan metode Spontaneous Group Discussion (SGD) masuk dalam kategori sedang dengan presentase 62,07%. Hasil belajar tanpa menerapkan metode Spontaneous Group Discussion (SGD) dalam kategori sedang dengan presentase 76,92%. Sedangkan pengaruh penerapan metode Spontaneous Group Discussion (SGD) terhadap hasil belajar mata pelajaran Ekonomi Bisnisdiperoleh hasil dengan harga thitungl 6,27 sedangkan ttabel 2,00. Karena thitung 6,27 tidak terletak diantara – ttabel < thitung < +ttabel yaitu -2,00 dan +2,00 maka dapat disimpulkan bahwa H0 ditolak dan Ha diterima.

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Herlina, Herlina. "Penerapan Teknik Ice Breaking untuk Meningkatkan Motivasi Belajar Ekonomi di Kelas XII IPS SMAN 3 Kayuagung." Jurnal Teknologi Pendidikan : Jurnal Penelitian dan Pengembangan Pembelajaran 7, no. 1 (April 14, 2022): 36. http://dx.doi.org/10.33394/jtp.v7i1.5006.

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This study aims to increase the motivation to learn the economics of class XI IPS students at SMAN 3 Kayuagung through the application of ice breaking techniques. The research method used is classroom action research conducted in two cycles. Each cycle consists of 4 stages, namely planning, implementation, observation and reflection. The data collection technique in this research used observation sheets and tests, then the data were analyzed descriptively. The results showed that the activities of students and student learning outcomes increased in each cycle, namely in the first cycle, students' learning activities increased by 60% to 85%. and learning completeness reached 62.07%. While in Cycle II the learning activities of students were 90% to 97% and learning completeness reached 89.66%. So the conclusion of this research is that the application of ice breaking technique can increase learning motivation and learning outcomes of XII IPS students of SMAN 3 Kayuagung.

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Herlina, Herlina. "Penerapan Teknik Ice Breaking untuk Meningkatkan Motivasi Belajar Ekonomi di Kelas XII IPS SMAN 3 Kayuagung." Jurnal Teknologi Pendidikan : Jurnal Penelitian dan Pengembangan Pembelajaran 7, no. 1 (April 14, 2022): 36. http://dx.doi.org/10.33394/jtp.v7i1.5006.

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This study aims to increase the motivation to learn the economics of class XI IPS students at SMAN 3 Kayuagung through the application of ice breaking techniques. The research method used is classroom action research conducted in two cycles. Each cycle consists of 4 stages, namely planning, implementation, observation and reflection. The data collection technique in this research used observation sheets and tests, then the data were analyzed descriptively. The results showed that the activities of students and student learning outcomes increased in each cycle, namely in the first cycle, students' learning activities increased by 60% to 85%. and learning completeness reached 62.07%. While in Cycle II the learning activities of students were 90% to 97% and learning completeness reached 89.66%. So the conclusion of this research is that the application of ice breaking technique can increase learning motivation and learning outcomes of XII IPS students of SMAN 3 Kayuagung.

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Wicaksana, Putu Aryasuta, Ida Bagus Alit Swamardika, and Rukmi Sari Hartati. "Analisis Usability Pada Aplikasi Ayoowork Baliyoni Menggunakan Use Questionnaire." Majalah Ilmiah Teknologi Elektro 20, no. 2 (December 25, 2021): 325. http://dx.doi.org/10.24843/mite.2021.v20i02.p17.

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Intisari— Pada dasarnya membangun sebuah sistem adalah untuk memenuhi kebutuhan penggunanya, dimana sistem harus mempertimbangkan kemudahan, kenyamanan serta kepuasan dalam menggunakan sistem informasi. Beberapa penelitian menunjukkan bahwa aspek-aspek tersebut tadi dapat diukur melalui analisis usability. Penelitian ini dilakukan untuk menganalisis kegunaan atau usability pada suatu sistem informasi manajemen proyek yang dikembangkan dan digunakan pada PT. Baliyoni Saguna Group. Pengukuran dilakukan dengan menggunakan Use Questionnaire yang diukur menggunakan skala Linkert dengan skala 5. Sehingga diharapkan dengan adanya penelitian ini kedepannya dapat menjadi acuan bagi perusahaan untuk terus mengembangkan sistem informasi guna mendukung kegiatan bisnis serta meningkatkan daya saing perusahaan. Hasil dari penelitian menunjukkan bahwa sistem informasi Ayoowork Baliyoni memiliki tingkat usability Baik dengan nilai interpretasi skor sebesar 62,07%. Dimana skor masing-masing aspek yang diukur adalah, usefulness dengan skor sebesar 593 atau 62,94%, ease of use sebesar 61,39%, ease of learning sebesar 60,59%, dan satisfaction dengan skor sebesar 63,03%.

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Lante, Samuel, Andi Tenriulo, and Neltje Nobertine Palinggi. "VARIASI GENETIK IKAN BERONANG (Siganus guttatus) ASAL PERAIRAN BARRU, LAMPUNG, DAN SORONG MENGGUNAKAN PENANDA RAPD (Random Amplified Polymorfism DNA)." Jurnal Riset Akuakultur 7, no. 2 (August 30, 2012): 195. http://dx.doi.org/10.15578/jra.7.2.2012.195-204.

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Evaluasi variasi genetik ikan beronang, Siganus guttatus telah dilakukan untuk mengetahui keragaman genetik di alam dalam upaya mendukung pembenihan secara terkontrol. Sampel ikan beronang diperoleh dari 3 (tiga) lokasi perairan di Indonesia yaitu: Barru (Sulawesi Selatan), Lampung (Sumatera), dan Sorong (Papua Barat) masing-masing sebanyak 10 ekor. Analisis variasi genetik dilakukan dengan metode random amplified polimorfism DNA (RAPD), menggunakan 5 (lima) primer (OPA3, OPA6, OPA7, OPA16, dan OPA20). Variasi genetik dianalisis menggunakan software TFPGA (Tools For Population Genetic Analysis). Kedekatan hubungan kekerabatan ditampilkan dalam dendrogram. Hasil Penelitian menunjukkan bahwa ikan beronang populasi Lampung mempunyai variasi genetik tertinggi yaitu 75,86%, dan terendah adalah populasi Barru (62,07%). Indeks similaritas ikan beronang tertinggi (0,9583) diperoleh antara populasi Barru dengan Sorong, dan indeks similaritas terendah (0,7996) antara populasi Sorong dengan Lampung. Berdasarkan jarak genetik ikan beronang pada penelitian ini diperoleh dua kelompok utama yaitu (1) Barru dan Sorong, dan (2) Lampung.

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Kisilevzky, Nestor. "Embolização uterina para tratamento de miomas sintomáticos: impacto na qualidade de vida." Radiologia Brasileira 40, no. 5 (October 2007): 289–96. http://dx.doi.org/10.1590/s0100-39842007000500003.

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OBJETIVO: Verificar a mudança na qualidade de vida de pacientes portadoras de miomatose uterina sintomática submetidas a tratamento por embolização. MATERIAIS E MÉTODOS: Quarenta mulheres portadoras de miomatose uterina sintomática que foram tratadas com a técnica de embolização responderam a um questionário de qualidade de vida antes e 12 semanas após o procedimento. RESULTADOS: Verificou-se que o escore médio relacionado com a gravidade dos sintomas nas 40 pacientes antes da embolização foi de 62,07 ± 6,34 e se modificou, com significância estatística após o tratamento, quando se verificou escore médio de 20,42 ± 3,81. Da mesma forma, comprovou-se a melhora na qualidade de vida pela modificação dos escores antes e depois do tratamento, o que também apresentou significância estatística, passando de 40,26 ± 2,98 para 85,06 ± 2,57. CONCLUSÃO: A embolização uterina provoca alívio evidente dos sintomas relacionados com a miomatose e proporciona melhora substancial da qualidade de vida das pacientes.

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Altaf, Amir, and Munkyo Seo. "Dual-Band Circularly Polarized Dielectric Resonator Antenna for WLAN and WiMAX Applications." Sensors 20, no. 4 (February 19, 2020): 1137. http://dx.doi.org/10.3390/s20041137.

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In this paper, a new dual-band circularly polarized (CP) dielectric resonator antenna for WLAN and WiMAX applications is proposed. The dielectric resonator has an asymmetric Y-shaped geometry. By properly selecting the length of the arms, the pairs of fundamental (TE 111 ) and second-order (TE 211 ) are excited separately at the design frequencies to radiate the CP wave. The measurement shows that the fabricated antenna exhibits a wide impedance bandwidth for |S 11 | < −10 dB of 62.07% (2.2–4.18 GHz). The far-field measurements in the broadside direction demonstrated a dual-band CP response with 3 dB ARBWs of 4.92%(2.38–2.5 GHz) at the lower and 12.64% (3.26–3.70 GHz) at the upper band. The measured CP bands cover the entire frequency range of WLAN (2.401–2.495 GHz) and WiMAX (3.4–3.69 GHz) at the lower and upper bands, respectively.

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Kumar, Pankaj, Manoj Kumar Singh, Avneesh Shukla, Rajesh Kumar, Sheo Pratap Singh, and Mukesh Pasupuleti. "Antioxidant Status in Neonatal Sepsis: A Case Control Study." Journal of Neonatology 36, no. 4 (December 2022): 263–67. http://dx.doi.org/10.1177/09732179221130655.

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Objective: Assessment of catalase, superoxide dismutase (SOD), and glutathione levels in neonatal sepsis. Methods: This case-control study was conducted from October 2017 to October 2018. All the patients having features suggestive of sepsis were subjected to a sepsis screen and blood culture. SOD, catalase, and glutathione assay was done in study subjects qualifying inclusion and exclusion criteria and in controls by spectrophotometric assay. Results: This study consisted of 58 cases and 46 controls. Out of 58 cases, 36 (62.07%) were male, 45 (77.59%) were term, and 23 (39.66%) cases were of normal birth weight. The levels of catalase ( P value = .0037) and glutathione ( P value = .0009) were lower, while SOD was higher ( P value = .0122) among cases with neonatal sepsis than controls. Conclusion: This study helps us in understanding antioxidant status in neonatal sepsis. However, studies with a larger sample size are needed to further understand inflammatory and antioxidant cascade.

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Sapriani, Bobby Poerwanto, and Aswi. "Implementasi Backpropagation Neural Network Pada Status Preeklampsia Ibu Hamil." Jurnal MSA ( Matematika dan Statistika serta Aplikasinya) 11, no. 2 (December 8, 2023): 72–76. http://dx.doi.org/10.24252/msa.v11i2.40657.

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Preeklampsia adalah penyakit yang diderita ibu hamil yang ditandai adanya kenaikan tekanan darah. Preeklampsia dapat membahayakan ibu dan juga janin karena dapat menyebabkan komplikasi, hingga kondisi terburuk yaitu kematian. Tujuan dari penelitian ini adalah untuk mengetahui hasil klasifikasi sekaligus prediksi berdasarkan lima variabel yang diduga mempengaruhi status preeklampsia ibu hamil. dengan menggunakan metode Backpropagation Neural Network (BNN). Data rekam medis ibu hamil di RSIA Sitti Khadijah 1 Makassar dan RS TK II Pelamonia Makassar yang berjumlah 167 data digunakan pada penelitian ini. Terdapat lima variabel yang diduga mempengaruhi status preeklampsia ibu hamil yaitu usia ibu saat kehamilan, paritas, riwayat penyakit, indeks massa tubuh, dan status pekerjaan ibu. Hasil studi menghasilkan bahwa skenario pembagian data terbaik yaitu data training 80% dan data testing 20% dengan hasil akurasi sebesar 67,65%, sensitifitas 69,23%, spesifikasi 66,67%, presisi 56,25%, Score 62,07%, nilai hidden layer 7 dan learning rate 0,001.

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Wolfe, Rachel M., Al‐Walid Mohsen, Cate Walsh Vockley, Carol A. Bertrand, Robert D. Nicholls, Paige Heiman, Leah M. Seibold, Jerry Vockley, and Lina Ghaloul‐Gonzalez. "Novel GUCY2C variant causing familial diarrhea in a Mennonite kindred and a potential therapeutic approach." American Journal of Medical Genetics Part A 185, no. 7 (May 5, 2021): 2046–55. http://dx.doi.org/10.1002/ajmg.a.62207.

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Carey, John C. "Parent‐authored memoirs: Lessons in the practice of narrative medicine." American Journal of Medical Genetics Part A 185, no. 9 (February 18, 2021): 2846–48. http://dx.doi.org/10.1002/ajmg.a.62107.

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Journal articles on the topic '62R07'

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