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1

Karagulyan, Avetik. "Sampling with the Langevin Monte-Carlo." Electronic Thesis or Diss., Institut polytechnique de Paris, 2021. http://www.theses.fr/2021IPPAG002.

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L’échantillonnage des lois aléatoires est un problème de taille en statistique et en machine learning. Les approches générales sur ce sujet sont souvent divisées en deux catégories: fréquentiste vs bayésienne. L’approche fréquentiste corresponds à la minimisation du risque empirique, c’est à dire à l’estimation du maximum vraisemblance qui est un problème d’optimisation, tandis que l’approche bayésienne revient à intégrer la loi postérieure. Cette dernière approche nécessite souvent des méthodes approximatives car l’intégrale n’est généralement pas tractable. Dans ce manuscrit, nous allons étudier la méthode de Langevin, basée sur la discrétisation de l’EDS de Langevin. La première partie de l’introduction pose le cadre mathématique et l’intérêt d’étudier plus avant la question de l'échantillonnage. La suite de l’introduction s’attache à la présentation des méthodes d’échantillonnage.Le premier article concerne les bornes non-asymptotiques sur la convergence en distance de Wasserstein de Langevin Monte-Carlo pour les fonctions de potentiel lisses et fortement convexes. Nous établissons d’abord des bornes explicites pour LMC avec des step-sizes variantes?. Puis nous étudions la convergence pour des fonctions de potentiel avec des gradients stochastiques. Enfin, deux types de discrétisation sont présentés, pour les potentiels plus réguliers.Dans la deuxième article nous abordons le problème d’échantillonnage de loi log-concave (pas fortement) en utilisant LMC, KLMC et KLMC2. Nous proposons une pénalisation quadratique constante de la fonction de potentiel. Puis nous prouvons des bornes non-asymptotiques sur l’erreur de Wasserstein de ces méthodes pour le choix de pénalisation optimale. Enfin, nous soulignons l’importance du choix de l’échelle pour le mesurage des complexités des différentes méthodes.La troisième contribution principales est concentrée sur la convergence de la diffusion de Langevin dans le case log-concave. Une pénalisation variable dans le temps est proposée pour la fonction de potentiel. Nous prouvons des bornes explicites pour cette méthode nommée Penalized Langevin Dynamics. A la fin, le lien entre les algorithmes de Langevin et l’optimisation convexe est établi, ce qui nous permet de prouver des bornes similaires pour le gradient flow
Sampling from probability distributions is a problem of significant importance in Statistics and Machine Learning. The approaches for the latter can be roughly classified into two main categories, that is the frequentist and the Bayesian. The first is the MLE or ERM which boils down to optimization, while the other requires the integration of the posterior distribution. Approximate sampling methods are hence applied to estimate the integral. In this manuscript, we focus mainly on Langevin sampling which is based on discretizations of Langevin SDEs. The first half of the introductory part presents the general mathematical framework of statistics and optimization, while the rest aims at the historical background and mathematical development of sampling algorithms.The first main contribution provides non-asymptotic bounds on convergence LMC in Wasserstein error. We first prove the bounds for LMC with the time-varying step. Then we establish bounds in the case when the gradient is available with a noise. In the end, we study the convergence of two versions of discretization, when the Hessian of the potential is regular.In the second main contribution, we study the sampling from log-concave (non-strongly) distributions using LMC, KLMC, and KLMC with higher-order discretization. We propose a constant square penalty for the potential function. We then prove non-asymptotic bounds in Wasserstein distances and provide the optimal choice of the penalization parameter. In the end, we highlight the importance of scaling the error for different error measures.The third main contribution focuses on the convergence properties of convex Langevin diffusions. We propose to penalize the drift with a linear term that vanishes over time. Explicit bounds on the convergence error in Wasserstein distance are proposed for the PenalizedLangevin Dynamics and Penalized Kinetic Langevin Dynamics. Also, similar bounds are proved for the Gradient Flow of convex functions
2

Spławski, Piotr. "Japonisme in Polish pictorial arts (1885-1939)." Thesis, University of the Arts London, 2013. http://ualresearchonline.arts.ac.uk/6205/.

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This thesis chronicles the development of Polish Japonisme between 1885 and 1939. It focuses mainly on painting and graphic arts, and selected aspects of photography, design and architecture. Appropriation from Japanese sources triggered the articulation of new visual and conceptual languages which helped forge new art and art educational paradigms that would define the modern age. Starting with Polish fin-de-siècle Japonisme, it examines the role of Western European artistic centres, mainly Paris, in the initial dissemination of Japonisme in Poland, and considers the exceptional case of Julian Fałat, who had first-hand experience of Japan. The second phase of Polish Japonisme (1901-1918) was nourished on local, mostly Cracovian, infrastructure put in place by the ‘godfather’ of Polish Japonisme Feliks Manggha Jasieński. His pro-Japonisme agency is discussed at length. Considerable attention is given to the political incentive provided by the outbreak of the Russo-Japanese war in 1904, which rendered Japan as Poland’s ally against its Russian oppressor. The first two decades of the 20th century are regarded as the ‘Renaissance’ of Japonisme in Poland, and it is this part of the thesis that explores Japanese inspirations as manifested in the genres of portraiture, still life, landscape, representations of flora and fauna, erotic imagery, and caricature. Japonisme in graphic and applied graphic arts, including the poster, is also discussed. The existence of the taste for Japanese art in the West after 1918 is less readily acknowledged than that of the preceding decades. The third phase of Polish Japonisme (1919-1939) helps challenge the tacit conviction that Japanese art stopped functioning as an inspirational force around 1918. This part of the thesis examines the nationalisation of heretofore private resources of Japanese art in Cracow and Warsaw, and the inauguration of official cultural exchange between Poland and Japan. Polish Japonisme within École de Paris, both before 1918 and thereafter, inspired mainly by the painting of Foujita Tsuguharu, is an entirely new contribution to the field. Although Japanese inspirations frequently appeared in Polish painting of the interwar period, it was the graphic arts that became most receptive to the Japanese aesthetic at that time. The thesis includes a case study of Leon Wyczółkowski’s interbellum Japonisme, and interprets it as patriotic transpositions of the work of Hiroshige and the Japanese genre of meisho-e. Japonisme in Polish design and architecture is addressed only in the context of the creation of Polish national style in design (1901-1939). Art schools in Britain and America became important centres for Japonisme at the beginning of the 20th century. The thesis considers the case of Cracow Academy of Fine Arts, which due to radical changes introduced by its new director Julian Fałat, became an important centre for the dissemination of the taste for Japanese art in Poland.
3

Kao, David. "The vibro-acoustic modelling and analysis of damage mechanisms in paper." Thesis, University of Greenwich, 2006. http://gala.gre.ac.uk/6205/.

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This thesis investigates the use of the acoustic emission (AE) monitoring technique for use in identifying the damage mechanisms present in paper associated with its production process. The microscopic structure of paper consists of a random mesh of paper fibres connected by hydrogen bonds. This implies the existence of the two damage mechanisms of interest, the failure of a fibre/fibre bond and the failure of a fibre. The majority of this work focuses on the development of a novel hybrid mathematical model which couples the mechanics of the mass/spring model to the acoustic wave propagation model for use in generating the acoustic signal emitted by complex structures of paper fibres under strain. A discussion of the coupling method is presented and the model is then analysed using a simple plucked fibre as a test case with a comparison between the numerical and experimental results. The hybrid mathematical model is then used to simulate small fibre networks aimed at providing information on the acoustic response of each damage mechanism. To do this the mass/spring model must successfully simulate the response of the fibre structure when undergoing a fibre/fibre bond failure or a fibre failure. This can be achieved by dynamically manipulating the mass and spring elements of the fibre structure. The simulated AEs from the two damage mechanisms are then analysed using a Continuous Wavelet Transform (CWT) to provide a two dimensional time/frequency representation of the signal. From the CWT certain features of the AEs can be attributed to each damage mechanism and as such a criteria for the time and frequency properties of each damage mechanism can be formulated. This criterion provides the basis for identifying the damage mechanisms present in the experimental data. The final contribution of this thesis is the investigation of training an intelligent classifier which can dynamically identify the AEs from the two damage mechanisms. This is achieved by converting the time and frequency criteria for each damage mechanisms into a set of features for the training of a Self-Organising Map (SOM). The significant step in this analysis is the method for the extraction of the features from the CWT of the AE. This work successfully combines four different scientific areas, paper physics, acoustic emission technology, data analysis and computational modelling to provide an insight into the micro-mechanics of paper. The most significant contribution of this work is the development of the hybrid model which has the ability to generate the acoustic response of a paper fibre structure undergoing two different damage processes. This alone has provided a significant insight into the micro-mechanics of paper to allow for the identification of the two damage mechanisms when the AEs are analysed with the CWT. Other contributions include the method used for the extraction of relevant features from the CWT to enable the training of a SOM for identifying the type of damage mechanism the AE originated from.
4

Peloso, Pietro. "Possibili soluzioni per garantire qos nelle comunicazioni inter-data centers in ambienti cloud computing." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amslaurea.unibo.it/6205/.

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Nel presente lavoro, partendo dalla definizione di alcuni punti chiavi del concetto di cloud computing, si è insistito molto sulle problematiche relative alle performance degli ambenti cloud, e alle diverse proposte attualmente presenti sul mercato con i relativi limiti. Dopo averle illustrate in modo dettagliato, le diverse proposte sono state tra loro messe a confronto al fine di evidenziare, per ciascuna di essa, tanto gli aspetti positivi quanto i punti di criticità.
5

Strusi, Valentina <1985&gt. "Toward a 3D in vitro model based on decellularized thymus to maintain adult thymic ephitelial cells functionality." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6205/.

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During my PhD,I have been develop an innovative technique to reproduce in vitro the 3D thymic microenvironment, to be used for growth and differentiation of thymocytes, and possible transplantation replacement in conditions of depressed thymic immune regulation. The work has been developed in the laboratory of Tissue Engineering at the University Hospital in Basel, Switzerland, under the tutorship of Prof.Ivan Martin. Since a number of studies have suggested that the 3D structure of the thymic microenvironment might play a key role in regulating the survival and functional competence of thymocytes, I’ve focused my effort on the isolation and purification of the extracellular matrix of the mouse thymus. Specifically, based on the assumption that TEC can favour the differentiation of pre-T lymphocytes, I’ve developed a specific decellularization protocol to obtain the intact, DNA-free extracellular matrix of the adult mouse thymus. Two different protocols satisfied the main characteristics of a decellularized matrix, according to qualitative and quantitative assays. In particular, the quantity of DNA was less than 10% in absolute value, no positive staining for cells was found and the 3D structure and composition of the ECM were maintained. In addition, I was able to prove that the decellularized matrixes were not cytotoxic for the cells themselves, and were able to increase expression of MHC II antigens compared to control cells grown in standard conditions. I was able to prove that TECs grow and proliferate up to ten days on top the decellularized matrix. After a complete characterization of the culture system, these innovative natural scaffolds could be used to improve the standard culture conditions of TEC, to study in vitro the action of different factors on their differentiation genes, and to test the ability of TECs to induce in vitro maturation of seeded T lymphocytes.
6

Laflamme, Patrick. "Superstitious perception in humans and convolutional neural networks." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/62605.

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The advent of complex Hierarchical Convolutional Neural Networks (HCNNs) has led to great progress in the field of computer vision, with modern implementations of HCNNs rivalling human performance in object recognition tasks. The design of HCNNs was inspired by current understanding of how the neurons of the human visual system are organized to support object recognition. There are researchers who claim that the computations undertaken by HCNNs are approximating those of the human visual system, because of their high accuracy in predicting the neural activity of regions of the brain involved in object classification (Cichy, Khosla, Pantazis, Torralba, & Oliva, 2016; Khaligh-Razavi & Kriegeskorte, 2014; Yamins et al., 2014). However, there has been little investigation of how HCNNs and humans compare on other tasks that HCNNs have not been trained on. Our study compared the similarity of one HCNN, AlexNet, and humans on a superstitious perception task that involves falsely recognizing a learned object in the absence of strong evidence for its presence. We began by validating a new technique that quantifies human performance on the superstitious perception task. The first phase of the research revealed that human behaviour in the task is dependent on whether participants employed an active or passive task strategy. Next, the responses of our HCNN to the same images were analyzed in a similar manner. The results showed that HCNNs behaved similarly to humans in some ways and differently in others. Specifically, the classification images generated for the HCNN were similar to those derived from human participants, but the HCNN was also more consistent in its responses than humans. A second finding was that the differences in human participants classification images (created by adopting active versus passive strategies) could not be accounted for by simply altering the proportion of false alarm responses in the HCNN. This suggests that HCNNs may be using criteria similar to humans’ perception when evaluating the likelihood of an object being present. The higher similarity between humans and HCNN in the passive condition suggests that the criteria similarities are largest when humans recruit minimal central executive resources in the decision-making process.
Arts, Faculty of
Psychology, Department of
Graduate
7

Tomm, Brandon M. "Attentional trade-offs under resource scarcity." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/62705.

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Resource scarcity poses challenging demands on the cognitive system. Budgeting with limited resources induces an attentional focus on the problem at hand, but it also comes with a cost. Specifically, scarcity causes a failure to notice beneficial information in the environment, or remember to execute actions in the future, that help alleviate the condition of scarcity. This neglect may arise as a result of attentional narrowing. Attentional trade-offs under scarcity can further determine memory encoding. In seven experiments, we demonstrated that participants under scarcity prioritized price information but neglected a useful discount when ordering food from a menu (Experiment 1); they showed better recall for information relevant to the focal task at a subsequent surprise memory test (Experiments 2 and 3); they performed more efficiently on the focal task but neglect a useful cue in the environment that could save them resources (Experiments 4-6); and they failed to remember the previous instructions to execute future actions that could save them resources (Experiment 7). These results collectively demonstrate that scarcity fundamentally shapes the way people process information in the environment, by directing attention to the most urgent task, while inducing a neglect of other information that can be beneficial. The attentional neglect and memory failures may lead to suboptimal behaviors that further aggravate the condition of scarcity. The results provide new insights on the behaviors of the poor, and also important implications for public policy and the design of welfare services and programs for low-income individuals.
Arts, Faculty of
Psychology, Department of
Graduate
8

Luke, Haliburton. "A clinical C-arm base-tracking system using computer vision for intraoperative guidance." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/62905.

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Mobile C-arm X-ray machines are commonly used for imaging during orthopaedic surgeries to visualize internal anatomy during procedures. However, there is evidence indicating that excess operating time and radiation exposure result from the use of scouting images to aid C-arm positioning during surgery. Additionally, C-arms are currently used primarily as a qualitative tool. Several techniques have been proposed to improve positioning, reduce radiation exposure, and increase quantitative utility, but they require accurate C-arm position tracking. There have been attempts by other research groups to develop C-arm tracking systems, but there are currently no solutions suitable for use in an operating room. The objective of this thesis is therefore to present the development and verification of a real-time C-arm base-tracking system called OPTIX (On-board Position Tracking for Intraoperative X-rays). The proposed tracking system uses a single floor-facing camera mounted to the base of a C-arm. A computer vision algorithm was developed that tracks motion relative to the operating room floor. This system is capable of relative motion tracking as well as absolute position recovery for previous positions. The accuracy of the system was evaluated on a real C-arm in a simulated operating room. The experimental results demonstrated that the relative tracking algorithm can measure C-arm translation with errors of less than 0.75% of the total distance travelled, and orientation with errors better than 5% of the cumulative rotation. With the incorporated loop closure step, OPTIX can be used to achieve C-arm repositioning with translation errors of less than 1.10±0.07 mm and rotation errors of less than 0.17 ±0.02°. These results are well within the desired system requirements of 5 mm and 3.1°. The system has shown promising results for use as a C-arm base-tracking system. The system has clinically acceptable accuracies and should lead to a reduced need for scouting images when re-obtaining a previous position. The base-tracking system can be integrated with a C-arm joint tracking system, or implemented on its own for steering guidance. When implemented in an operating room, OPTIX has the potential to lead to a reduction in operating time and harmful radiation exposure to surgical staff.
Applied Science, Faculty of
Graduate
9

Ntšekhe, Mathe V. K. "Building IKhwezi, a digital platform to capture everyday Indigenous Knowledge for improving educational outcomes in marginalised communities." Thesis, Rhodes University, 2018. http://hdl.handle.net/10962/62505.

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Aptly captured in the name, the broad mandate of Information and Communications Technologies for Development (ICT4D) is to facilitate the use of Information and Communication Technologies (ICTs) in society to support development. Education, as often stated, is the cornerstone for development, imparting knowledge for conceiving and realising development. In this thesis, we explore how everyday Indigenous Knowledge (IK) can be collected digitally, to enhance the educational outcomes of learners from marginalised backgrounds, by stimulating the production of teaching and learning materials that include the local imagery to have resonance with the learners. As part of the exploration, we reviewed a framework known as Technological Pedagogical Content Knowledge (TPACK), which spells out the different kinds of knowledge needed by teachers to teach effectively with ICTs. In this framework, IK is not present explicitly, but through the concept of context(s). Using Afrocentric and Pan-African scholarship, we argue that this logic is linked to colonialism and a critical decolonising pedagogy necessarily demands explication of IK: to make visible the cultures of the learners in the margins (e.g. Black rural learners). On the strength of this argument, we have proposed that TPACK be augumented to become Indigenous Technological Pedagogical Content Knowledge (I-TPACK). Through this augumentation, I-TPACK becomes an Afrocentric framework for a multicultural education in the digital era. The design of the digital platform for capturing IK relevant for formal education, was done in the Siyakhula Living Lab (SLL). The core idea of a Living Lab (LL) is that users must be understood in the context of their lived everyday reality. Further, they must be involved as co-creators in the design and innovation processes. On a methodological level, the LL environment allowed for the fusing together of multiple methods that can help to create a fitting solution. In this thesis, we followed an iterative user-centred methodology rooted in ethnography and phenomenology. Specifically, through long term conversations and interaction with teachers and ethnographic observations, we conceptualized a platform, IKhwezi, that facilitates the collection of context-sensitive content, collaboratively, and with cost and convenience in mind. We implemented this platform using MediaWiki, based on a number of considerations. From the ICT4D disciplinary point of view, a major consideration was being open to the possibility that other forms of innovation—and, not just ‘technovelty’ (i.e. technological/- technical innovation)—can provide a breakthrough or ingenious solution to the problem at hand. In a sense, we were reinforcing the growing sentiment within the discipline that technology is not the goal, but the means to foregrounding the commonality of the human experience in working towards development. Testing confirmed that there is some value in the platform. This is despite the challenges to onboard users, in pursuit of more content that could bolster the value of everyday IK in improving the educational outcomes of all learners.
10

Massie, Mark (Mark Edward). "A generalized optimization methodology for isotope management." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/62705.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2010.
"Research funded by the Department of Energy's Advanced Fuel Cycle Initiative Fellowship"--Abstract. Cataloged from PDF version of thesis.
Includes bibliographical references (p. 91-93).
This research, funded by the Department of Energy's Advanced Fuel Cycle Initiative Fellowship, was focused on developing a new approach to studying the nuclear fuel cycle: instead of using the trial and error approach currently used in actinide management studies in which reactors are designed and then their performance is evaluated, the methodology developed here first identified relevant fuel cycle objectives like minimizing decay heat production in a repository, minimizing Pu-239 content in used fuel, etc. and then used optimization to determine the best way to reach these goals. The first half of this research was devoted to identifying optimal flux spectra for irradiating used nuclear fuel from light water reactors to meet fuel cycle objectives like those mentioned above. This was accomplished by applying the simulated annealing optimization methodology to a simple matrix exponential depletion code written in Fortran using cross sections generated from the SCALE code system. Since flux spectra cannot be shaped arbitrarily, the second half of this research applied the same methodology to material composition of fast reactor target assemblies to find optimal designs for minimizing the integrated decay heat production over various timescales. The neutronics calculations were performed using modules from SCALE and ERANOS, a French fast reactor transport code. The results of this project showed that a thermal flux spectrum is much more effective for transmuting used nuclear fuel. In the spectral optimization study, it was found that a thermal flux spectrum is approximately five times more effective at reducing long-term decay heat production than a fast flux spectrum. This conclusion was reinforced by the results of the target assembly material optimization study, which found that by adding an efficient moderator to a target assembly designed for minor actinide transmutation, the amount of decay heat generated over 10,000 years of cooling can be reduced by over 50% through a single pass in a fast reactor without exceeding standard cladding fluence limits.
by Mark Massie.
S.M.
11

Bimpikis, Kostas. "Strategic delay and information exchange in endogenous social networks." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/62405.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Sloan School of Management, Operations Research Center, 2010.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 160-165).
This thesis studies optimal stopping problems for strategic agents in the context of two economic applications: experimentation in a competitive market and information exchange in social networks. The economic agents (firms in the first application, individuals in the second) take actions, whose payoffs depend on an unknown underlying state. Our framework is characterized by the following key feature: agents time their actions to take advantage of either the outcome of the actions of others (experimentation model) or information obtained over time by their peers (information exchange model). Equilibria in both environments are typically inefficient, since information is imperfect and, thus, there is a benefit in being a late mover, but delaying is costly. More specifically, in the first part of the thesis, we develop a model of experimentation and innovation in a competitive multi-firm environment. Each firm receives a private signal on the success probability of a research project and decides when and which project to implement. A successful innovation can be copied by other firms. We start the analysis by considering the symmetric environment, where the signal quality is the same for all firms. Symmetric equilibria (where actions do not depend on the identity of the firm) always involve delayed and staggered experimentation, whereas the optimal allocation never involves delays and may involve simultaneous rather than staggered experimentation. The social cost of insufficient experimentation can be arbitrarily large. Then, we study the role of simple instruments in improving over equilibrium outcomes. We show that appropriately-designed patents can implement the socially optimal allocation (in all equilibria) by encouraging rapid experimentation and efficient ex post transfer of knowledge across firms. In contrast to patents, subsidies to experimentation, research, or innovation cannot typically achieve this objective. We also discuss the case when signal quality is private information and differs across firms. We show that in this more general environment patents again encourage experimentation and reduce delays. In the second part, we study a model of information exchange among rational individuals through communication and investigate its implications for information aggregation in large societies. An underlying state (of the world) determines which action has higher payoff. Agents receive a private signal correlated with the underlying state. They then exchange information over their social network until taking an (irreversible) action. We define asymptotic learning as the fraction of agents taking an action that is close to optimal converging to one in probability as a society grows large. Under truthful communication, we show that asymptotic learning occurs if (and under some additional conditions, also only if) in the social network most agents are a short distance away from "information hubs", which receive and distribute a large amount of information. Asymptotic learning therefore requires information to be aggregated in the hands of a few agents. We also show that while truthful communication is not always optimal, when the communication network induces asymptotic learning (in a large society), truthful communication is an equilibrium. Then, we discuss the welfare implications of equilibrium behavior. In particular, we compare the aggregate welfare at equilibrium with that of the optimal allocation, which is defined as the strategy profile a social planner would choose, so as to maximize the expected aggregate welfare. We show that when asymptotic learning occurs all equilibria are efficient. A partial converse is also true: if asymptotic learning does not occur at the optimal allocation and an additional mild condition holds at an equilibrium, then the equilibrium is inefficient. Furthermore, we discuss how our learning results can be applied to several commonly studied random graph models, such as preferential attachment and Erdos-Renyi graphs. In the final part, we study strategic network formation in the context of information exchange. In particular, we relax the assumption that the social network over which agents communicate is fixed, and we let agents decide which agents to form a communication link with incurring an associated cost. We provide a systematic investigation of what types of cost structures and associated social cliques (consisting of groups of individuals linked to each other at zero cost, such as friendship networks) ensure the emergence of communication networks that lead to asymptotic learning. Our result shows that societies with too many and sufficiently large social cliques do not induce asymptotic learning, because each social clique would have sufficient information by itself, making communication with others relatively unattractive. Asymptotic learning results if social cliques are neither too numerous nor too large, in which case communication across cliques is encouraged.
by Kostas Bimpikis.
Ph.D.
12

Korre, Hasan. "On the development of a low-cost lithographic interferometer." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/62105.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 61-63).
Interference lithography is a technique for making one- and two-dimensional periodic nanostructures using interference of two coherent light beams. Despite their successes, the size, maintenance, and cost of interference lithography tools have prevented periodic nanostructures from being ubiquitous in academia and industry. Here, a novel approach is described whereby the conventional optical source - a bulky and expensive metal-vapor laser - is replaced by a newly available, low-cost blue laser diode. Additionally, the passive alignment of a lens tube is utilized to simplify the construction of a spatial filter. The resulting custom-built interference lithography tool is able to print large-area (~ cm2 ) periodic patterns. The tool has a small footprint (~0.2 M2 ) and can be assembled for less than 6000 USD.
by Hasan Korre.
S.M.
13

Snella, Michael T. "Drift correction for scanning-electron microscopy." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/62605.

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Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student submitted PDF version of thesis.
Includes bibliographical references (p. 91-92).
Scanning electron micrographs at high magnification (100,000x and up) are distorted by motion of the sample during image acquisition, a phenomenon called drift. We propose a method for correcting drift distortion in images obtained on scanning electron and other scanned-beam microscopes by registering a series of images to create a drift-free composite. We develop a drift-distortion model for linear drift and use it as a basis for an affine correction between images in the sequence. The performance of our correction method is evaluated with simulated datasets and real datasets taken on both scanning electron and scanning helium-ion microscopes; we compare performance against translation only correction. In simulation, we exhibit a 12.5 dB improvement in SNR of our drift-corrected composite compared to a non-aligned composite, and a 3 dB improvement over translation correction. A more modest 0.4 dB improvement is measured on the real image sets compared to translation correction alone.
by Michael T. Snella.
M.Eng.
14

Liu, Junying M. Eng Massachusetts Institute of Technology. "Assembly cell layout and Kanban system design for an oilfield services company." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/62505.

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Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2010.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 46).
The thesis describes the layout design of new gauge assembly lab for an oilfield services company. A relationship diagram was created to categorize all the workstations and activities in the assembly line. Three layouts were proposed based on the categorization. One layout that facilitated the assembly flow best and met the requirement of human factors was selected. This new layout enables the company to meet the increased demand in 2011. In addition, Kanban system was also introduced to this assembly line to reduce lead time to one month and to reduce inventory by 40%, respectively.
by Junying Liu.
M.Eng.
15

CEDILLO, GONZALEZ ESTHER ALEJANDRA. "DOCUMENTACION DE LA TRANSFORMACION OPERATIVA DEL MODELO DE SERVICIO DE CAJEROS AUTOMATICOS." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2013. http://hdl.handle.net/20.500.11799/62605.

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Desde el inicio del proyecto debe quedar claro el alcance del proyecto, no solo ante quien contrata el servicio, sino también a todos los involucrados del proyecto, pues de no dejarse claro el alcance pueden generarse expectativas de cosas que no serán tocadas como parte del proyecto. El manejo de expectativas no siempre es sencillo, por lo que el consultor debe de estar siempre atento a los comentarios que realicen los involucrados y si identifica una expectativa que se encuentre fuera del alcance, debe indicarle al involucrado que se validará con los responsables del proyecto para determinar si debe ser considerado dentro del alcance, cuando se realice este tipo de compromisos el consultor debe dar la retroalimentación del punto lo antes posible al involucrado y en caso de que aun no se cuente con una retroalimentación indicar el motivo.
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Souza, Sara Kanter Pinto de. ""A função social da propriedade industrial e o direito à proteção da saúde"." Master's thesis, Faculdade de Medicina da Universidade do Porto, 2011. http://hdl.handle.net/10216/62205.

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17

Rebelo, Luís Francisco de Gouveia Durão Pina. "The Economics of Health and Health Care: Assessing health determinants and impacts on an aging population." Doctoral thesis, Faculdade de Economia da Universidade do Porto, 2010. http://hdl.handle.net/10216/62305.

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18

Dias, Ana Lucélia Silva. "As políticas públicas de juventude em descontinuidades : uma análise das práticas de evasão no ProJovem Urbano de Porto Alegre." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/62105.

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O presente trabalho investigou o ProJovem Urbano, tendo como objetivo analisar como a evasão se torna um problema para o Programa Nacional de Inclusão de Jovens. Desde sua implementação, em 2005, o ProJovem é apresentado como uma das principais iniciativas articuladas pela Política Nacional de Juventude para, dentre outros motivos, dar conta do grande número de jovens que estariam precocemente fora da escola. O ProJovem Urbano, uma das novas modalidades do programa que unificou outros projetos para juventude a partir de 2007, atende jovens de 18 a 29 anos, alfabetizados, mas que não concluíram o Ensino Fundamental. Apesar de configurar novas estratégias para reinserção escolar, o acompanhamento do ProJovem Urbano no município de Porto Alegre evidenciou que a grande desistência dos jovens atendidos adquire centralidade, mobilizando-se como problema a ser combatido pelos gestores e educadores. Nesse contexto, a partir dos referenciais de Michel Foucault, tomamos o procedimento genealógico como princípio analítico, apreendendo-o enquanto estratégia de pensamento. A partir do operador analítico “práticas”, domínio de análise Foucaulteana, buscamos desnaturalizar o conceito de evasão, problematizando como se constituem as práticas de criação, formação e implementação do ProJovem Urbano, que tornam a evasão um problema, no contexto do Município de Porto Alegre. Para o desenvolvimento da pesquisa consideramos documentos oficiais que compreendem o momento de elaboração e desenvolvimento do ProJovem Urbano; documentos do período em que as políticas públicas de juventude adquirem maior consistência no cenário nacional; diários de campo produzidos durante inserções realizadas em 3 núcleos do ProJovem Urbano em Porto Alegre; questionários respondidos por jovens atendidos pelo programa em 3 encontros de discussão; entrevistas com jovens, educadores e gestores envolvidos com a formação. Nossa análise remete que a evasão é produzida como problema na mediada em que as práticas de formação e criação do ProJovem Urbano são atravessadas por três eixos. A saber, a educação como meio de efetivar a cidadania e a inclusão social; como forma de proteção e controle sobre a vulnerabilidade; e como problema político condicionado ao desenvolvimento socioeconômico. Articulando efeitos de poder e jogos de verdade, ao prescrever modos de circulação dos jovens nos territórios sociais, estas práticas naturalizam o fracasso nas trajetórias juvenis, situando a evasão como problema também nas formas de gestão e no desenho das Políticas Públicas de Juventude.
This work investigated the program called ‘ProJovem Urbano’, analyzing how the evasion became a problem to the National Program for Youth Social Inclusion. Since its implementation in 2005, the ‘ProJovem’ program is presented as one of the greatest initiatives articulated by the National Youth Policy for, among other reasons, help the large number of young people prematurely out of school. The ‘ProJovem Urbano’, one of the new modalities of the program that unified other projects for youth since 2007, serves people from 18 to 29 years old, young literate people but that have not already completed de elementary school. Although new strategies for school reintegration were created, the monitoring of the ‘ProJovem Urbano’ in the city of Porto Alegre, Brazil, revealed that the large abandonment of youths attended in the program acquires centrality, mobilizing it as a problem to be solved by managers and teachers. In this context, based on Michel Foucault’s ideas, we took the genealogical procedure as an analytical principle, apprehending it as a strategy of thinking. From the analytical operator "practice", domain of Foucault’s analysis, we denaturalized the notion of evasion, discussing how are constituted the practices of creating, training and implementation of the ‘ProJovem Urbano’ that turn evasion a problem in the context of the Municipality of Porto Alegre. We considered official documents that comprise the moment of preparation and development of the ‘ProJovem Urbano’, documents of the period in which public policies for youth acquire greater consistency in the national scene, field journals produced during insertions performed in three centers of ‘ProJovem Urbano’ in Porto Alegre, questionnaires filled out by youth enrolled in the program in three discussion meetings and interviews with youth, teachers and managers involved with the education. Our analysis refers that the evasion is produced as a problem in the sense that the education practices and the creation of the ‘ProJovem Urbano Program’ are crossed by three axes: Namely, education as means of effecting social inclusion and citizenship; as a form of protection and control over the vulnerability and as a political problem associated to socioeconomic development. Articulating the effects of power and games of true and false, by prescribing modes of movement of young people in social territories, we notice practices that naturalize the failure in youth trajectories, setting the evasion as a problem also in management forms and to formulate Public Policies for Youth.
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Yapi, Litha. "Ammonium fluoride : transition metal purification." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/62805.

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Pelchem NF3 plant produces an ammonium acid fluoride waste stream. The material of construction for the piping and stirrer fabrication in the plant is Monel. As a predominantly nickel-copper alloy, with minute quantities of carbon, manganese, silicon, sulfur and iron, these may leach into process fluids involved. The two biggest constituents of Monel contaminate the ammonium acid fluoride waste stream. Despite being the lesser of the two in terms of the composition of the Monel, copper is higher in concentration than nickel in the waste stream: the solubility of copper (II) cation in ammonium fluoride is higher than that of nickel (II) cation. Additionally, the ammonium acid fluoride is stored in steel barrels because of the relatively high process temperature that preclude the use of polymeric drums. This results in the leaching of iron from the steel drum to the solution. Pelchem expressed an interest in a suitable method of purification of ammonium fluoride, with specific interest of removing nickel (II) cation, copper (II) cation as well as iron (II) cation. The constraints to consider when selecting the appropriate methods are operating costs as well as the capital costs, but the most important factor to consider is the effectiveness of the method in removing the contaminant. In this regard, cationic exchange resins are very suitable, and they are very practical for industrial applications. In its simplest form, ammonium fluoride solutions are prepared by bubbling ammonia gas through solutions of hydrofluoric acid. Quite a few interesting uses of ammonium fluoride are available, these include as a chemical modifier in lead analysis, synthesis of beta zeolites, etc. The most prominent use is as a technical grade etchant in the electronics industry. The main aim of this research was to investigate ion exchange as a method of removing contaminants from Pelchem ammonium acid fluoride. Static equilibrium/selectivity experiments reveal that Purolite S930 Plus and Lewatit TP207 show a great affinity for the copper cation. For the limiting step of the reaction, the analysis includes apparent kinetics modelling contrasted with mass transfer modelling. In the case of reaction kinetics, Arrhenius and Van’t hoff equations were used to determine reaction parameters: the activation energies are 14 368 J∙mol-1 and 24 116 J∙mol-1, for Purolite and Lewatit respectively. The pre-exponential constants are 2 213 and 269 682 L2∙min-1∙mol-2 for Purolite and Lewatit in that order. The heats of reaction are -26 555 and -4 696 J∙mol-1 for Purolite and Lewatit respectively. Whilst the equilibrium pre-exponential constants are 75 057and 150 for Purolite and Lewatit respectively. Diffusivities for the two resins were found to be in reasonable agreement with those recorded in literature. They follow a temperature dependency trajectory. Weisz-Prater analysis of the observed reaction rate and the diffusion rate, in the two resins, reveals that intraparticle diffusion is the limiting step in the reaction.
Dissertation (MEng)--University of Pretoria, 2017.
Chemical Engineering
MEng
Unrestricted
20

Schubart, Ondine Chantal. "A situation analysis of health education for young children to promote prevention and control of malaria in the Ha-Makuyu Village." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/62905.

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Malaria is a deadly disease transmitted by the female Anopheles mosquito in many tropical and subtropical regions. This disease kills more 500 000 people annually, yet these deaths can be prevented if malaria is diagnosed timeously and treated effectively. Despite many initiatives to fight this disease, the incidence of malaria remains high in the Mutale Municipality in the Limpopo Province where the majority of malaria cases have been diagnosed over the past decade. This study aimed to explore the current status of health education for the prevention and control of malaria in primary schools in the Ha-Makuya Village, Vhembe District in the Mutale Municipality. The possible existence of educational strategies in place to promote malaria awareness in schools was investigated. It was assumed that strategies such as collaboration between the Departments of Health and Education on health education, and policy provision on the topic could lead to children learning about malaria prevention and control, and in turn, inform their parents, leading to the broader community practicing preventive measures, leading to the reduction and eventual elimination of malaria in endemic areas. A qualitative research approach was employed in this study, informed by the interprevist paradigm, using a case study. Data was collected through interviews with relevant stakeholders in this matter, such as principals, teachers, nurses and a district official, in order to gain an understanding of their views on and perception of this disease, and to gauge their knowledge on practices to promote malaria awareness through health education. Existing policies were also analysed to examine possible content on this matter. It was found that even though some of the stakeholders’ knowledge on malaria-related issues was lacking, their attitude towards prevention strategies was positive. It was further found that, even though some effort was being made to work together, collaboration between the stakeholders was at best tenuous. Policy was also found to be lacking on provisions for the successful implementation of health education programmes for the prevention and control of malaria in schools. Recommendations to address these issues were made to the Departments of Health and Education, principals, teachers, policy-makers, as well as for further study.
Dissertation (MEd)--University of Pretoria, 2017.
Early Childhood Education
MEd
Unrestricted
21

Bertacchi, Pepe Mónica María. "Archeas halófilas como causa de alteraciones en tripas bovinas saladas." Doctoral thesis, Universitat Politècnica de València, 2016. http://hdl.handle.net/10251/62205.

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[EN] The main objective of this study was the analysis, description, characterization and impact of red-orange colorations observed in salted bovine casings (intestines), ready for marketing. To achieve this, over the course of three years, an investigation was conducted in two slaughterhouses to assess the industrial process of obtaining cattle intestines (primary process); and three tripe shops to study the secondary process of obtaining salted bovine casings. A salt processing establishment was also visited. A sensory evaluation of the contaminated products was performed, and samples of salt, bovine casings, and water were collected and subjected to physico-chemical, microbiological, molecular, and histological analyses. Our study concludes that the microorganisms responsible for the color alterations are extremely halophilic archae, Haloarcula, Halogranum or Haloterrígena and Haloferax being the identified Genus. Archaea enter the system by cross-contamination through food grade salt. Our studies show that an extremely low load of archaea is sufficient for its development. According to our observations, red-orange coloration can be found in the salt and brine from the surface of open-head drums with only 20 days of storage, and up to a year and a half. Furthermore, electron microscope scans reveal that these halophilic microorganisms can form biofilms, adhering to the casings' surface, altering its histological structure, and therefore their properties when making sausages. In the establishments surveyed it was found that, despite all the measures taken to ensure product quality and safety (GMP, SSOP and HACCP), quality changes in the product were present. We conclude that this is a problem underestimated at an industrial level, and where preventive measures play a major role.
[ES] El objetivo principal de este trabajo fue el análisis, descripción, caracterización e incidencia de las coloraciones rojo anaranjadas observadas en tripas bovinas saladas (intestinos), prontas para su comercialización. Para ello, en el curso de tres años, se realizó una investigación en dos establecimientos de faena para evaluar el proceso industrial de obtención de intestinos bovinos (proceso primario); y en tres triperías, para estudiar el proceso secundario de industrialización de las tripas bovinas saladas. También se asistió a un establecimiento procesador de sal. Se realizó evaluación sensorial de los productos contaminados y se recolectaron muestras de sal, tripas vacunas y agua para estudios microbiológicos, físico-químicos, moleculares e histológicos. Este trabajo concluye que los microorganismos responsables de las alteraciones son arqueas halófilas extremas identificándose los géneros Haloarcula, Halogranum o Haloterrígena y Haloferax. Las arqueas ingresan al sistema por contaminación cruzada a través de la sal de grado alimentario. Los estudios muestran que una carga extremadamente baja de arqueas es suficiente para su desarrollo. De acuerdo a las observaciones realizadas, se constatan coloraciones rojo anaranjadas en la sal y salmuera de la superficie de las tarrinas con tan sólo 20 días de almacenamiento y hasta un año y medio. Por otra parte, la microscopía electrónica muestra que estos microorganismos halófilos pueden formar biopelículas, adhiriéndose a la superficie de la tripa, alterando su estructura histológica y, por tanto, sus propiedades al momento de la elaboración de embutidos. En los establecimientos estudiados se constató que, a pesar de adoptar todas las medidas para garantizar la inocuidad del producto (GMP, SSOP y HACCP), se presentaban alteraciones de calidad en el producto. En conclusión, se trata de un problema subestimado a nivel industrial, y donde las medidas preventivas desempeñan un papel fundamental.
[CAT] L'objectiu principal d'este treball va ser l'anàlisi, descripció, caracterització i incidència de les coloracions roig ataronjades observades en budells bovins salats (intestins), promptes per a la seua comercialització. Per a això, en el curs de tres anys, es va realitzar una investigació en dos establiments de faena per a avaluar el procés industrial d'obtenció d'intestins bovins (procés primari); i en tres triperies, per a estudiar el procés secundari d'obtenció de budells bovins salats. També es va assistir a un establiment processador de sal. Es va realitzar avaluació sensorial dels productes contaminats i es van recol¿lectar mostres de sal, budells vacunes i aigua per a estudis microbiològics, fisicoquímics, moleculars i histològics. Este treball conclou que els microorganismes responsables de les alteracions són arqueges halòfiles extremes identificant-se els gèneres Haloarcula, Halogranum o Haloterrigena i Haloferax. Les arqueges ingressen al sistema per contaminació encreuada a través de la sal de grau alimentari. Els estudis mostren que una càrrega extremadament baixa d'arqueges és suficient per al seu desenrotllament. D'acord amb les observacions realitzades, es constaten coloracions roig ataronjades en la sal i salmorra de la superfície de les terrines amb tan sols 20 dies d'emmagatzemament i fins a un any i mig. D'altra banda, la microscòpia electrònica mostra que estos microorganismes halòfils poden formar biofilms, adherint-se a la superfície del budell, alterant la seua estructura histològica i, per tant, les seues propietats al moment de l'elaboració d'embotits. En els establiments estudiats es va constatar que, a pesar d'adoptar totes les mesures per a garantir la innocuïtat del producte (GMP, SSOP i HACCP), es presentaven alteracions de qualitat en el producte. En conclusió es tracta d'un problema subestimat a nivell industrial, i on les mesures preventives exercixen un paper fonamental.
Bertacchi Pepe, MM. (2016). Archeas halófilas como causa de alteraciones en tripas bovinas saladas [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/62205
TESIS
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Nikoi, Paul Ashaley. "Library e-resources and services to enable postgraduate studies at The Regional Maritime University (RMU), Ghana." Diss., University of Pretoria, 2016. http://hdl.handle.net/2263/62105.

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The Regional Maritime University (RMU) Ghana, pays between $5,000 and $8,000 in annual subscription for e-resources with the Consortium of Academic and Research Libraries in Ghana (CARLIGH) to support postgraduate studies and lecturers. However, statistics from the library and library research rooms indicate very low use of the e-resources by postgraduate students and lecturers. This study is therefore set to address the problem of low patronage of the e-resources. The study aimed at finding what library e-resources and services could be provided by the RMU library to enable postgraduate studies. The main research tool that was used to collect data was a questionnaire with both closed and open-ended questions. The total population for this study was 25 postgraduate students and five lecturers. Thirty (30) copies of the questionnaire were distributed to postgraduate students and their lecturers at the department of ports and shipping administration with a response rate of 66.66%. Undergraduate students were excluded from this study. The study revealed that the RMU library has enough e-resources to support both academic and research work and this is known to the majority (75%) of the respondents who use them occasionally. The main reasons for the occasional use of the e-resources were lack of user-education, user-training and lack of off-campus access to fully put the resources to maximum use. Apart from the study suggesting an extensive user education and awareness creation initiative, it also recommends the rolling out of new user services to enhance usage of the e-resources.
Mini Dissertation (MIT)--University of Pretoria, 2016.
Information Science
MIT
Unrestricted
23

Rebelo, Luís Francisco de Gouveia Durão Pina. "The Economics of Health and Health Care: Assessing health determinants and impacts on an aging population." Tese, Faculdade de Economia da Universidade do Porto, 2010. http://hdl.handle.net/10216/62305.

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24

Souza, Sara Kanter Pinto de. ""A função social da propriedade industrial e o direito à proteção da saúde"." Dissertação, Faculdade de Medicina da Universidade do Porto, 2011. http://hdl.handle.net/10216/62205.

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25

Меньщиков, В. А. "Совершенствование технологии переработки медьсодержащего сырья в ТРОФ-конвертере : автореферат диссертации на соискание ученой степени кандидата технических наук : 05.16.02." Thesis, б. и, 2018. http://hdl.handle.net/10995/62605.

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26

Lachos, Victor H., and Filidor V. Labra. "Multivariate skew-normal/independent distributions: properties and inference." Pontificia Universidad Católica del Perú, 2014. http://repositorio.pucp.edu.pe/index/handle/123456789/97108.

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Liu (1996) discussed a class of robust normal/independent distributions which contains a group of thick-tailed cases. In this article, we develop a skewed version of these distributions in the multivariate setting, and we call them multivariate skew normal/independent distributions. We derive several useful properties for them. The main virtue of the members of this family is that they are easy to simulate and lend themselves to an EM-type algorithm for maximum likelihood estimation. For two multivariate models of practical interest, the EM-type algorithm has been discussed with emphasis on the skew-t, the skew-slash, and the contaminated skew-normal distributions. Results obtained from simulated and two real data sets are also reported.
Liu (1996) discute una clase de distribuciones robustas a las que apela como normal/independiente, y que contiene un grupo de distribuciones de colas pesadas. En este artículo desarrollamos una versión asimétrica de tales distribuciones en un escenario multivariado, a las que llamaremos distruciones normales asimétricas independientes multivariadas. Para tales distribuciones derivamos algunas propiedades. La principal virtud de los miembros de esta familia es que son fáciles de simular y se prestan a un algoritmo de tipo EM para realizar estimaciones de máxima verosimilitud de sus parámetros. Para dos modelos multivariados de interés práctico se discute el algoritmo EM con énfasis en las distribuciones t-asimétrica, slash asimétrica y normal asimétrica contaminada. Los resultados obtenidos a partir de simulaciones y de dos conjuntos de datos reales son reportados.
27

Aranda, Joan. "Aportació als mètodes de seguiment tridimensional d'objectes d'alta velocitat d'operació mitjançant l'estereovisió." Doctoral thesis, Universitat Politècnica de Catalunya, 1997. http://hdl.handle.net/10803/6205.

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28

Gaspar, Ricardo. "Open Asset Managment : uma solução de gestão de ativos baseada em tecnologias Open Source." Master's thesis, Escola Superior de Tecnologia do Instituto Poitécnico de Setúbal, 2014. http://hdl.handle.net/10400.26/6205.

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Dissertação de Mestrado em Informática de Gestão
Nos dias que decorrem, uma correta e eficiente gestão de ativos faz toda a diferença quando é corretamente executada. A gestão de ativos pode aumentar a competitividade empresaral e trazer benefícios financeiros. Existem muitas soluções no mercado que permitem efetuar a gestão de ativos, no entanto são dispendiosas e as empresas menores acabam por não investir neste tipo de gestão. Este projeto tem como objetivo permitir com que micro, pequenas e médias empresas (PMEs) tenham acesso a uma solução, desenvolvido sobre tecnologia Open Source que seja acessível financeiramente. O software criado designa-se de Open Asset Management e permite fazer uma correta e eficiente gestão de ativos. É intuitivo e robusto, e possibilita uma adaptação rápida por parte dos utilizadores. O desenvolvimento do OpenAM foi baseado numa análise de mercado aos softwares para gestão de ativos já existentes. Reunindo toda a informação da análise foi possível o desenvolvimento enquadrado do software de gestão de ativos. Foi utilizada uma metodologia ágil de desenvolvimento, através do desenvolvimento do software por módulos, onde o seu controlo de qualidade foi verificado periodicamente. Após o desenvolvimento da solução Open Asset Management, esta foi divulgada a sete entidades distintas para que fosse recolhida Informação com o intuito de validar a qualidade do software.
29

Kito, Masao, Mitsuo Maehara, and Kazuyoshi Watanabe. "Three Types of Voltage-Dependent Calcium Currents Developing inCultured Human Neuroblastoma Cells." 名古屋大学医学部, 1999. http://hdl.handle.net/2237/6205.

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30

Chen, Jason I. "The Role of Threat-based Beliefs in Mental Health Help-Seeking Processes for Depression." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6205.

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Mental illness among college students is a significant public health concern. Among mental health issues, one of the most prevalent and impairing is depression. Although many students experience depression, the majority do not seek help. Past research has shown that stigma beliefs are associated with help-seeking, but interventions targeting stigma have been unsuccessful at increasing help-seeking prompting the need to explore alternative models. Currently, there has been little research evaluating the role of threat-based beliefs related to help-seeking processes. As well, it remains unclear how different threat-based beliefs may interact and be related to help-seeking intentions. The purpose of these studies was to develop new measures that assess threat-based beliefs based on facilitating threats, as defined by perceived severity, mortality, loss of functioning, and loss of control threats and obstructing threats, as defined by general stigma, interpersonal rejection, and workplace rejection beliefs. As well, it was hypothesized that facilitating threats would be positively associated with help-seeking intentions and that this relationship would be moderated by obstructing threats such that higher levels of obstructing threats would attenuate the relationship between facilitating threats and help-seeking. Data were analyzed using structural equation modeling. The measurement development phase (N = 240) supported the proposed factor structure with the exclusion of the stigma and severity threat measures. When testing the moderation hypothesis (N = 212), results did not support the hypothesized relationships between facilitating threats, obstructing threats, and help-seeking intentions. The implications of these results for future research, theory, and prevention program directions are discussed.
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de, Oliveira Jauvane Cavalcante. "Issues in large scale collaborative virtual environments." Thesis, University of Ottawa (Canada), 2002. http://hdl.handle.net/10393/6205.

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Collaborative Virtual Environments (CVE) are virtual reality spaces that enable participants to collaborate and share objects, as if physically present in the same place. CVE concepts have been used in many systems in the past few years. Applications of such technology range from military combat simulations to various civilian commercial applications. These collaboration spaces have strict performance requirements. Today, there are many such systems developed specifically for collaboration. At the same time, some relatively new standards that address multiuser virtual environments and shared spaces have become available; however, most of these standards have been developed assuming that a small number of users would be interacting at a given time. The architectures available today provide support for a modest number of users but they fail if too many users are "present" together in a small "space" in the Virtual World. In this work, we first evaluate the currently available standards for the case of a very large number of users. An Adaptive Hybrid Architecture for VEry Large Virtual EnvironmenTs (VELVET) is then introduced. VELVET allows a large number of users to interact in a CVE. It also supports small groups of users, but it is in the large environment case that shows its greatest potential. VELVET introduces a novel adaptive area of interest management, which supports heterogeneity amongst the various participants. That allows users in a supercomputer with a high-speed networking connection to successfully collaborate with others in not-so-powerful systems behind a slow dial-up connection. In order to make a Collaborative Virtual Environment more interesting to users, it is possible to "stitch" together copies of areas which users may have interest in from one Virtual World into another. This procedure augments the physical size of a Virtual World, and creates a potentially larger number of users within the World, first because of the "embedding" and second since the added attractions may work as an incentive for some more users to join the "embedded" World. On the other hand this procedure brings up a series of problems related with consistency, which are also addressed in the thesis. We introduce a methodology which ensures that all copies of a given area of a World are kept consistent among them, as well as with the original world. We also apply this methodology in VELVET, as well as in other Architectures. Additionally, we introduce other approaches to be used when a less strict consistency model is sufficient.
32

Lesio, Catherine Ann. "Accountability for mental health counseling in schools /." Online version of thesis, 2007. http://hdl.handle.net/1850/6205.

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33

O'Brien, S. "Jump cutting: tracing parkour as invisible spectacle through the filmic city." Thesis, University of Canterbury. Centre for Fine Arts, Music and Theatre, 2011. http://hdl.handle.net/10092/6205.

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Seen as the art of moving from one location to another in the most efficient manner possible, parkour is a physical discipline preoccupied with gymnastic efficiency through the surmounting of urban architectural features that are designed to both facilitate and impede everyday pedestrian movements in the city. This thesis is an examination of the practice, and its representation in various films, YouTube clips, documentaries and advertisements. Symbiotically linked with its own depiction in these mediated and narrativised depictions, parkour plays out as a contradictory interfacing with a metropolitan environment that it sees (and feels) as both delimiting and psycho-geographically malleable. The elemental contradiction addressed in this thesis is the practice’s emergence, making-visible and containment through and within the discussed media, even as it evolves as a system of total, bodily evasion from retinal powers of civic design and filmic surveillance. In investigating this topic, I was drawn to a number of popular texts that both document and reciprocally inspire a global echelon of parkour practitioners, called traceurs. In sequence, I will analyse YouTube videos posted by this expanding audience of enthusiasts; parkour narrative films that incorporate the practice’s stylized acrobatic idioms; and blockbuster feature films that both literally reference parkour through the use of explosive cameos, and metaphorically provoke the discipline’s desire for superhero transcendence of the city’s gridded matrix. Throughout my textual and performative enquiry, and through comparative, anecdotal experiences I have had everyday on the street, I have increasingly sensed that parkour’s radically kinetic approach to professed liberation in and from the city is only one of the most conspicuous of many locomotive rhythms in the city. It is both this nominal and physical conspicuousness that belies the traceur’s attempted, limpid escape from the interning and channeling structures of the built environment. It is the less photogenic, unnamed and sometimes accidental paces enacted in equally chance, pedestrian encounters that become an even more imaginative catalyst for ambivalent evasion and liberation.
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Provencher, David. "Imagerie 3D de l'anatomie interne d'une souris par dynamique de fluorescence." Mémoire, Université de Sherbrooke, 2012. http://hdl.handle.net/11143/6205.

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L'imagerie médicale sur petits animaux est d'une grande utilité en recherche préclinique, car elle permet d'imager in vivo et en 3D l'intérieur de l'animal. Ceci sert au développement de nouveaux médicaments et au suivi de l'évolution de certaines pathologies. En effet, les techniques d'imagerie éliminent la nécessité de sacrifier les animaux, ce qui permet le suivi de processus biomoléculaires sur un même individu et l'obtention de données statistiquement plus significatives. Cependant, l'information moléculaire recueillie s'avère généralement de faible résolution spatiale, notamment en imagerie optique à cause de la diffusion de la lumière, et donc difficile à localiser dans le corps de l'animal. Le jumelage de modalités d'imagerie complémentaires permet donc d'obtenir des images anatomiques et moléculaires superposées, mais cela s'avère toutefois relativement coûteux. Le projet présenté vise à améliorer une technique d'imagerie 2D toute optique à faible coût permettant d'obtenir une carte approximative 3D des organes internes d'une souris. Cette technique devrait permettre le recalage spatial automatique d'informations moléculaires obtenues sur le même appareil, bien que cela n'ait pas encore été démontré. L'amélioration apportée par le projet consiste à obtenir des images anatomiques 3D, plutôt que 2D, en utilisant une caméra tournante et des techniques de vision numérique stéréo. Pour ce faire, la technique existante est d'abord reproduite. Celle-ci consiste à injecter de l'ICG , un marqueur fluorescent non spécifique qui demeure confiné au réseau vasculaire une fois injecté, à une souris anesthésiée. De par leurs métabolismes distincts et le temps que met l'ICG à atteindre chacun d'eux, la dynamique de fluorescence varie entre les organes, mais demeure relativement uniforme à l'intérieur d'un même organe. Certains organes peuvent donc être segmentés par des techniques appropriées de traitement de signal, telles l'analyse en composantes principales et la régression par moindres carrés non négative. Un système d'imagerie à caméra rotative comme le QOS® de Quidd permet d'obtenir des images 2D segmentées de l'anatomie. interne de l'animal selon plusieurs plans de vue. Ces plans de vue servent à reconstruire l'information anatomique en 3D par des techniques de vision numérique. La procédure pourrait être répétée avec un ou plusieurs marqueurs fluorescents fonctionnalisés dans le but d'obtenir des images moléculaires 3D du même animal et de les superposer aux images anatomiques 3D. La technique développée devrait ainsi permettre d'obtenir à faible coût et de manière toute optique des images 3D anatomiques et moléculaires recalées spatialement automatiquement.
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Wilson, Adelyn Lorraine McKenzie. "Sources and method of the Institutions of the law of Scotland by Sir James Dalrymple, 1st Viscount Stair, with specific reference to the law of obligations." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/6205.

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This thesis examines the sources and method used by Sir James Dalrymple, 1st Viscount Stair, when writing and revising his seminal work, the Institutions of the Law of Scotland (1681). In doing so, it focuses particularly on Stair’s titles on the law of obligations. The thesis shows how Stair used learned authority and continental legal treatises. It demonstrates that Stair relied particularly upon Hugo Grotius’ De jure belli ac pacis (1625), Petrus Gudelinus’ De jure novissimo (1620), and Arnoldus Vinnius’ Commentarius academicus et forensis (1642), and, to a lesser extent, Vinnius’ Jurisprudentia contracta (1624-1631) and Arnoldus Corvinus’ Digesta per aphorismos (1642). It establishes when, in the process of writing and later revising the Institutions, Stair first used and when he returned to these continental legal treatises. It explains Stair’s pattern of borrowing from these treatises, and shows how his method and pattern of borrowing changed as he revised the Institutions. It establishes Stair’s purpose in consulting each of these works and how he was influenced by them. Overall, the thesis explains Stair’s method of writing and his use of sources and authorities, places his work in the context of continental jurisprudence, and thus significantly enhances current understanding of Stair’s Institutions.
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Levent, Eriskin. "Estimating inter-deployment training cycle performances." Thesis, Monterey, California. Naval Postgraduate School, 2003. http://hdl.handle.net/10945/6205.

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Approved for public release; distribution is unlimited
The objective of this thesis is to estimate Inter-Deployment Training Cycle (IDTC) performances of the US Pacific Fleet surface ships, which are evaluated at the end of the Basic Training Phase, by using Command Metrics Tool (COMET) metrics. The basic objective was primarily to decide whether the COMET database can be used to estimate performances of ships, and to build regression models to estimate Final Evaluation Problem (FEP) performances of ships. This study develops multivariate logit regression models to examine and explore the structure of the data sets. Most of the models developed according to statistical criteria include only the intercept, indicating that there is no real relationship between the COMET metrics and IDTC performances. The assessments made at the end of FEP are not good Measure of Performances (MOPs) by which to assess ships' IDTC performances.
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Silva, Ana Cristina Barbosa Gomes da. "Alemanha e China : estudo comparativo da evolução económica (1980-2011) e análise das relações bilaterais de comércio e IDE." Master's thesis, Instituto Superior de Economia e Gestão, 2013. http://hdl.handle.net/10400.5/6205.

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Mestrado em Economia Internacional e Estudos Europeus
A economia mundial está em mutação, tendência resultante das dinâmicas impostas pela globalização que transformou um mundo bipolar em multipolar, onde emergem agora novos protagonistas e novas parcerias estratégicas. Neste enquadramento, a dissertação compara as evoluções económicas da Alemanha e da China entre 1980 e 2011 e analisa as relações bilaterais sino-alemãs de comércio e IDE, procedendo: (i) à revisão teórica dos conceitos de crescimento económico, convergência, globalização, relações económicas internacionais e competitividade; e (ii) à análise de indicadores, entre os quais, macroeconómicos, setoriais, demográficos, competitividade, comércio e IDE. A capacidade de adaptação às exigências da globalização e os fatores competitivos nacionais são a base do sucesso destas performances. Com diferentes maturidades económicas, a Alemanha (gigante histórico) e a China (gigante emergente) estão entre as maiores economias do mundo e partilham a apologia histórica da industrialização, a estabilidade macroeconómica, a liderança do comércio internacional e o estatuto de economias superavitárias. Distinguem-se, designadamente, pelos ritmos de crescimento, pela posição líquida de investimento no estrangeiro, pela política cambial, pela composição da procura interna e pelo perfil de comércio internacional. As relações bilaterais demonstram uma parceria estratégica no comércio e no IDE com lucros recíprocos, afigurando-se, contudo, novos desafios resultantes do surgimento de argumentos de concorrência mútua e da reconfiguração da economia mundial. O estudo assume particular interesse perante a ainda reduzida panóplia de análises comparativas entre as economias alemã e chinesa e face a possibilidade de outras economias retirarem lições destas experiências de crescimento e cooperação económica.
The world economy is changing. This is a tendency resulting from the dynamics imposed by globalization, which transformed a bipolar world into a multipolar one, where new protagonists and new strategic partnerships are now emerging. In this framework, the paper compares the German and Chinese economic evolutions between 1980 and 2011 and analyzes Sino-German trade and FDI bilateral relations, proceeding: (i) to the theoretical review of the concepts of economic growth, convergence, globalization, international economic relations and competitiveness; and (ii) to the analysis of indicators, including, macroeconomics, sectorial, demographic, competitiveness, trade and FDI. The capacity of adaptation to the globalization requirements and the competitive national factors are the basis to the success of these performances. Having different economic maturities, Germany (historic giant) and China (emergent giant) are among the biggest economies in the world and share the historic defense of industrialization, the macroeconomic stability, the international trade leadership and the surplus economy status. They differ, namely, by their economic rates growth, net outward investment, exchange rate policies, domestic demand composition and profile of international trade. The bilateral relationships demonstrate a strategic partnership in trade and FDI with reciprocal profits drawing, however, new challenges resulting from the emergence of arguments to mutual competition and from the reconfiguration of the world economy. This paper assumes particular interest facing the still reduced panoply of comparative analyses between German and Chinese economies and the possibility of other economies learn lessons from these experiences of economic growth and cooperation.
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Sendim, Paula Joana Rodrigues. "Prática de ensino supervisionada em Ensino Pré-Escolar e Ensino do 1º Ciclo do Ensino Básico." Master's thesis, Instituto Politécnico de Bragança, Escola Superior de Educação, 2013. http://hdl.handle.net/10198/6205.

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O presente relatório final de estágio surge no âmbito da unidade curricular da Prática de Ensino Supervisionada e pretende descrever e analisar dois estágios pedagógicos: um na Educação Pré-escolar e outro no 1.º Ciclo do Ensino Básico, uma vez que estes constituem-se fundamentais para o desenvolvimento e construção de um ser humano integrado numa sociedade A prática profissional foi assumida como uma etapa fundamental para o nosso desempenho profissional futuro. As instituições nas quais realizámos a ação educativa foram ambas de rede pública, mas em cotextos geográficos distintos. Uma no litoral norte e a outro no interior norte. No decorrer deste percurso, promoveram-se experiências que potenciaram aprendizagens significativas, integradoras e muito enriquecedoras, quer do ponto de vista pessoal quer profissional. Ao longo da descrição e reflexão das experiências de aprendizagem, interpretam-se os dados, procurando evidenciar as opções educativas e valorizando sempre o papel da criança, bem como, evidenciar a interligação dos conteúdos. Ambos os estágios desenvolvidos permitiram-nos refletir sobre a ação educativa e também sobre as estratégias e motivações que levam as crianças a construir os seus próprios conhecimentos. Na reflexão, destaca-se a importância que esta experiência teve para nós, permitindo a construção de novos conhecimentos resultantes de toda a prática pedagógica e toda a convivência com as crianças. This internship final report arises in the context of the curricular unit of Supervised Teaching Practice, and aims to describe and analyze two educational internships: one in Preschool Education and another on the first Cycle of Basic Education, since these are essential for the development and construction of an integrated human being in a society. The professional practice was taken over as a fundamental step to our future professional performance. The institutions in which we had the educational activities were both from the public network, but in distinct geographic contexts. One on the North Coast and the other in the Northern interior. In the course of this journey, were promoted experiences with significant learning, integrative and enriching, both personally and professionally. During the description and reflection of learning experiences, date is interpreted, looking to evidence the educational options and always valuing role of the child, as well as highlight the interconnection of the contents. Both internships have allowed us to reflect on the educational action and also on the strategies and motivations that lead children to construct their own knowledge. On reflection, we highlight the importance that this experience meant for us, by acquiring new knowledge resulting from all the pedagogical practice and the close dealing with children.
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Rojas, Jaimes Jesús Eduardo. "Detección e identificación molecular de Leishmania (Viannia) guyanensis en garrapatas de la especie Rhipicehaulus (Boophilus) microplus colectadas de Pecari tajacu, Madre de Dios." Master's thesis, Universidad Nacional Mayor de San Marcos, 2017. https://hdl.handle.net/20.500.12672/6205.

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Examina una muestra de garrapatas obtenidas de porcinos silvestres, Tapirus terrestris (“tapir o sachavaca”) y tres Pecari tajacu (“sajino”) de los distritos de Tahuamanú y Las Piedras, respectivamente. Se obtuvieron 81 garrapatas: 14 Amblyomma naponense, 18 Amblyomma scalpturatum, 3 Amblyomma oblongoguttatum, 4 Amblyomma latepunctatu, 1 Amblyomma ovale, y 41 Rhipicephalus (Boophilus) microplus. Luego de la identificación macroscópica y microscópica de los especímenes, se procedió a extraer el DNA y se identificó por PCR el kDNA de Leishmania (Viannia) en tres Rhipicephalus (Boophilus) microplus colectadas de Pecari tajacu y en una de ellas por PCR-HRM se pudo identificar a Leishmania (V.) guyanensis, agente causal de la leishmaniasis cutánea. Por lo tanto estos hallazgos amplían la información y distribución de Leishmania (V) guyanensis encontrado en Rhipicephalus (Boophilus) microplus en zonas silvestres y que podrían vincularse a nuevas formas de transmisión del agente causal de la enfermedad, argumentando la importancia del estudio de las garrapatas y su relación como agente transmisor de Leishmania sp.
Tesis
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Welsh, Sasha. "Imagining what it means to be ''human'' through the fiction of J.M. Coetzee's Life & Times of Michael K and Cormac McCarthy's The Road." University of the Western Cape, 2018. http://hdl.handle.net/11394/6205.

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Magister Artium - MA
Through a literary analysis of two contemporary novels, J.M. Coetzee's Life & Times of Michael K (1983) and Cormac McCarthy's The Road (2006), in which a common concern seems to be an exploration of what it means to be human, the thesis seeks to explore the relationship between human consciousness and language. This dissertation considers the development of a conception of the human based on rationality, and which begins in the Italian Renaissance and gains momentum in the Enlightenment. This conception models the human as a stable knowable self. This is drawn in contrast to the novels, which figure the absence of a stable knowable self in the representation of their protagonists. The thesis thus interrogates language's capacity to provide definitional meanings of the ''human.'' On the other hand, although language's capacity to provide essential meanings is questioned, its abundant expressive forms give voice to the experience of human being. Drawing on a range of fields of enquiry, both philosophical, linguistic, and bio-ethical, this thesis seeks to explore the connection between human consciousness and the medium of language. It considers how the two novels in question play with the concept of language to produce or imagine other ways of thinking about human existence, and other ways of creating meaning to human existence through the representation of their novels.
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Souza, Luiz Fernando de. "Inosina extracelular como intermediária na silnalização do TNF-alfa em células de sertóli em cultura." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2004. http://hdl.handle.net/10183/6205.

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As purinas extracelulares ATP e adenosina têm sido extensivamente estudadas em diferentes modelos e tipos celulares na modulação de várias respostas fisiológicas e patológicas. No entanto, a inosina extracelular, produto da degradação da adenosina pela Adenosina Deaminase (ADA), foi considerada por muito tempo um simples metabólito inativo. Recentemente, diversos trabalho têm demonstrado que este nucleosídeo possui importante papel na regulação de inúmeros processos. As células de Sertóli são as células somáticas dos túbulos seminíferos, e possuem fundamental importância na espermatogênese. Estas células, expressam diferentes purinoreceptores, estando estes envolvidos na regulação de diversas funções destas células relacionadas ao controle do desenvolvimento das células germinativas. No testículo, o TNF-α é produzido pelas espermátides redondas e pelos macrófagos ativados presentes no espaço intersticial. As células de Sertóli expressam os dois receptores descritos para TNF-α, TNF-RI (p55) e TNF-RII (p75), e diversos trabalhos tem descrito a modulação de diferentes funções destas células por esta citocina, incluindo a modulação da produção de NO e da fosforilação das MAPKs. Recentemente, foi descrita a modulação purinérgica da sinalização por TNF-α, bem como, a atividade ATPásica do receptor TNF-R1. Assim, nesta dissertação, foi estudado o efeito do TNF-α nos níveis das purinas extracelulares, além da possível participação purinérgica na sinalização desta citocina, em células de Sertóli em cultura. O tratamento destas células com TNF-α leva a um rápido aumento (5minutos) da concentração extracelular da inosina, que se prolonga até seis horas de incubação, sem alterar a concentração dos demais nucleotídeos e seus metabólitos. A inosina modula a produção de NO e a fosforilação das MAPKs ERK½ e p38 em células de Sertóli em cultura, aparentemente, através de diferentes mecanismos, sendo o primeiro efeito independente do receptor para adenosina A1 e o segundo efeito dependente da ativação deste receptor. Além disso, a inosina extracelular está envolvida na modulação da produção de NO e da fosforilação da MAPK ERK½ em células de Sertóli em cultura pelo TNF-α. A inibição do acúmulo de inosina estimulado pelo TNF-α através da incubação com um inibidor da adenosina deaminase cancela o aumento da produção de NO estimulada por esta citocina. Além disso, o bloqueio do receptor para adenosina A1 por antagonistas específicos impede o aumento na fosforilação da ERK½ estimulada por esta citocina. Assim, nesta dissertação, é descrito um papel intermediário da inosina extracelular na sinalização do TNF-α em células de Sertóli em cultura.
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Бойко, Віталій, and Назарій Євгенович Бурак. "Інформаційна війна як загроза безпеці держави." Thesis, Львівський державний університет безпеки життєдіяльності, 2019. http://hdl.handle.net/123456789/6205.

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Tronchin, Enrico M. "The systematics, biology and distribution of the Gelidiaceae (Rhodophyta) of South Africa and related taxa." Doctoral thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/6205.

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Bibliography: leaves 194-214.
The diversity, biology and distribution of the red algal family Gelidiaceae (Rhodophyta) of South Africa (and related taxa) were investigated, being relatively poorly understood and taxonomically problematic. Prior to this study, 21 species in 6 genera were reported from South Africa Now there are 29 species in 3 genera (though molecular data indicates that there is possibly a new, undescribed genus) of which 16 are Gelidium species, 5 are Pterocladiella species and 8 are Ptilophora species. The phylogenetic relationships and taxonomic status of the genera Beekerella, Ptilophora, Onikusa and Suhria, and various species within Gelidium and Pterocladiella, were reassessed.
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Reder, Sheri Darlyn. "The interpersonal communication effects of humorous and fear-arousing public service announcements recommending condom use /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/6205.

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Doxey, Christopher Robert. "A Neuroimaging Investigation of the Effects of Age and Sleep on Pattern Separation." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6205.

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Effective memory representations must be specific to prevent interference between episodes that may overlap in terms of place, time, or items present. Pattern separation, a computational process performed by the hippocampus overcomes this interference by establishing non-overlapping memory representations. This project explores pattern separation and how it is impacted by age and sleep. Experiment 1. Structures of the medial temporal lobe (MTL) are known to be involved in declarative memory processes. However, little is known about how age-related changes in MTL structures, white matter integrity, and functional connectivity affect pattern separation processes in the MTL. In the present study, we used magnetic resonance imaging (MRI) to measure the volumes of MTL regions of interest, including hippocampal subfields (dentate gyrus, CA3, CA1, and subiculum) in healthy older and younger adults. Additionally, we used diffusion tensor imaging to measure white matter integrity for both groups. Finally, we used functional MRI to acquire resting functional connectivity measures for both groups. We show that, along with age, the volume of left CA3/dentate gyrus predicts memory performance. Differences in fractional anisotropy and the strength of resting functional connections between the hippocampus and other cortical structures implicated in memory processing were not significant predictors of performance. As previous studies have only hinted, it seems that the size of left CA3/dentate gyrus contributes more to successful discrimination between similar mnemonic representations than other hippocampal sub-fields, MTL structures, and other neuroimaging correlates. Accordingly, the implications of aging and atrophy on lure discrimination capacities are discussed. Experiment 2. Although it is widely accepted that declarative memories are consolidated during sleep, the effects of sleep on pattern separation have yet to be elucidated. We used whole-brain, high-resolution functional neuroimaging to investigate the effects of sleep on a task that places high demands on pattern separation. Sleep had a selective effect on memory specificity and not general recognition memory. Activity in brain regions related to attention, visual acuity, and visual recall demonstrated an interaction between sleep and delay. Surprisingly, there was no effect of sleep on hippocampal activity using a group-level analysis. To further understand the role of the hippocampus on our task, we performed a representational similarity analysis. We investigated whether hippocampal activity associated with looking at novel stimuli correlated more with similar-looking (lure) stimuli or repeated stimuli. Results indicate that while a single night's sleep does not significantly impact hippocampal responses, the hippocampus does treat lure stimuli similarly as it does novel stimuli.
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Cutler, Jared. "An Investigation of the Impact of Chld Care Quality on Child Outcomes Using Structural Equation Modeling." DigitalCommons@USU, 2004. https://digitalcommons.usu.edu/etd/6205.

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The quality of a child care setting is believed by many child care researchers to have an impact on the development of children in child care. While a considerable amount of research has been done regarding the impact of child care quality on child outcomes, an examination of literature reviews on the topic reveals that there is a lack of consensus in the field on the question of whether child care quality has a substantial impact on children's development. The present study assessed the impact child care quality has on child outcomes. A dataset from the NICHD Early Child Care Study involving 878 subjects was used. Analyses utilizing structural equation modeling indicated that child care quality has a substantial impact on children's development, even when the influence of demographic and family variables is taken into account.
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Gholz, Eric L. "Exploring Strategies Leaders Use to Engage Employees." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/6205.

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The purpose of this qualitative, single case study was to explore strategies that leaders used to engage employees. The conceptual framework for this study was Saks's multidimensional approach to employee engagement. Semistructured interviews were conducted with 5 leaders from an office design company in the midwestern region of the United States who had a minimum of 2 years of experience of engaging employees. Company archival documents related to employee engagement were also collected. Data analysis consisted of compiling the data, coding for emergent and a priori codes, disassembling the data into common codes, reassembling the data into themes, interpreting the meaning, and reporting the themes. Seven themes emerged from data analysis: (a) communication, (b) employee involvement, (c) employee development, (d) top-down approach with manager buy in, (e) flexibility with time, (f) tailored strategies for different demographics, and (g) engagement with the workspace/environment. The implications of this study for positive change are that organizational leaders can incorporate these strategies to engage employees to achieve a competitive edge over competition. Engaged employees could benefit local communities and could have the flexibility to participate in community activities and foster positive social change.
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McLaughlin, Jacob Ryan. "Control of swelling, electrochemical, and elongation properties of photopolymers through the modification of structure." Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6205.

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Modifying photopolymer structure on the molecular and nanoscale level permits tailoring materials for use in a wide variety of applications. Understanding the fundamentals behind polymer structure at these levels permits the control of material properties. This work gains insight into the modification of structure on two levels, the nanoscale by use of structure templates and the molecular scale through the modification of polymer network formation. Lyotropic liquid crystals (LLCs) are a type of self-assembling surfactant system, which in combination with photopolymerization can be used to template ordered nanostructure within polymer materials. This structure can be controlled and utilized to influence the properties of a polymer material. This research examines materials used as templating agents and the types of nanostructures that may be obtained. Additionally, their effects upon the LLC templating process and material properties is determined. Structured polymers are created using LLC templates in pursuit of materials for use in water purification processes and electrochemical devices. Through a more complete understanding of the fundamentals of the templating process, the work presented here extends the LLC templating technique to a greater variety of materials and applications in the water remediation and energy storage fields. The second portion of this research is the use of reversible addition fragmentation chain transfer (RAFT) to modify photopolymer networks. RAFT agents are utilized to control the propagation reaction to create networks with increased homogeneity between network crosslinks. By increasing the uniformity of the polymer network, increases in polymer elongation and toughness as well as decreases in polymer modulus are observed. The effects of RAFT agent addition on the network formation and the final properties of the photopolymer is examined. By understanding the mechanisms behind this modification technique, photopolymers can be extended into new applications where increased elongation and toughness is valued.
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Puglierin, Carlotta <1988&gt. "The position of the Italian port system in the changing European and international context: threats and opportunities." Master's Degree Thesis, Università Ca' Foscari Venezia, 2015. http://hdl.handle.net/10579/6205.

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The aim of this dissertation is to provide an overview of the modalities with which the major trends that have been wide spreading in the world of today have affected ports and the maritime sector in Europe. Firstly, a digression concerning the relevance of ports for intermodal transportation throughout the European area will be presented, focusing in particular on the function of those structures, usually determined by their nature and physical characteristics. Secondly, after a brief digression about the winds of change which have globally affected the transportation field in the last decades, the attention will be drawn to the existing geo-political and geo-economic differences between the Northern and the Southern European port systems. The lack of a European common regulation on the maritime subject, the ever more required adaptability to the continuously evolving commercial and economic sectors, the ever stricter environmental standards, and the problem of financing port reforms are among the most challenging problems that ports are called to face in the modern era. Thirdly, the attention will be focused on the Mediterranean sea and its international revaluation, that risks to be undermined by a tough competition between ports belonging to this same region. Then, some of the projects involving this area in recent years will be presented. Lastly, some considerations about the Italian situation will be provided, in order to understand what has already been done and what remains to do for the improvement of the position of our country in the international scenario.
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Weinert, Maria. "Regulation of cellular energy metabolism : implications for Parkinson's disease." Thesis, Imperial College London, 2017. http://hdl.handle.net/10044/1/62905.

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Abstract:
Mutations in DJ-1 (PARK7) gene cause recessive, early-onset Parkinson‘s disease. DJ-1 is a neuroprotective oncogene that translocates from the cytoplasm to mitochondria under cellular stress conditions. The neuroprotective role of DJ-1 against reactive oxygen species has been extensively studied but its normal, physiological function is not fully understood. 14-3-3beta is a conserved protein of the 14-3-3 family of chaperones that are implicated in regulation of metabolism in part through regulation of subcellular localisation of their targets. We found that 14-3-3beta interacts with DJ-1 in a phosphorylation-dependent manner. Furthermore, 14-3-3beta inhibits the translocation of DJ-1 to mitochondria under normal cell physiological conditions. The knockdown of 14-3-3beta leads to increased mitochondrial membrane potential, likely through the enhanced mitochondrial translocation of DJ-1. 14-3-3beta knockdown cells show increased proliferation rates under normoxia and hypoxia and are more sensitive to chemical inhibition of mitochondrial ATP production compared to control cell lines. These results suggest that the interaction between DJ-1 and 14-3-3beta plays a role in cellular metabolic balance by influencing the cellular preference for glycolysis or oxidative phosphorylation as the two main modes of ATP production. We also postulate that the neuronal metabolic balance, regulated by the interaction between DJ-1 and 14-3-3beta, is required for cellular adaptation to environmental stress or synaptic activity.

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