Dissertations / Theses on the topic '629.3.023:027'
To see the other types of publications on this topic, follow the link: 629.3.023:027.
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic '629.3.023:027.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
1
Бєлих, Віталій Ростиславович. "Конструкторсько-технологічне забезпечення електричної платформи "odi" для людей з інвалідністю (комплексна магістерська дисертація)." Master's thesis, КПІ ім. Ігоря Сікорського, 2019. https://ela.kpi.ua/handle/123456789/31365.
Full textAbstract:
На основі аналізу стану питання у сфері транспортування людей з обмеженими можливостями, визначено, що в розвинутих країнах, існують розробки, що дозволяють покращити умови транспортування, у тому числі оснащених електричними приводами руху. Такі технології вже доступні у більшості країн широкому загалу людей з середніми та високим рівнем достатку. Впроцесі роботи було створено дизайн транспортного засобу, проаналізовано та спроектовано систему задньої підвіски електричної платформи. Для перевірки отриманих результатів, було проведено комп’ютерну симуляцію підвіски. Виготовлений у масштабі 1:4 макет ферми задньої підвіски, та макет дизайну електричної платформи.Based on the analysis of the state of the issue in the field of transportation of people with disabilities, it is determined that in developed countries there are developments that can improve transportation conditions, including those equipped with electric movement drives. Such technologies are already available in most countries to a wide range of people with medium and high incomes.In the process, a vehicle design was created, the rear suspension system of the electric platform was analyzed and designed. To verify the results, a computer simulation of the suspension was carried out.Made in a 1: 4 scale layout of the rear suspension truss, and the layout design of the electric platform.
2
Bowd, Rebecca Elizabeth. "The purposes of reading in late Georgian Britain : science, medicine, industry and intellectual culture in the Leeds subscription libraries, 1768-1815." Thesis, University of Leeds, 2015. http://etheses.whiterose.ac.uk/11145/.
Full textAbstract:
This study of libraries in Leeds in the late Georgian era establishes why a range of subscription libraries came into being in the town in the mid eighteenth century, and provides a localised and integrated account of how several such libraries worked within the cultural economy of a provincial town. At the heart of this study is the question of how the Leeds libraries related to the reading and associate requirements of their first readers. Association, sociability, improvement and taste are words which usually describe the motivations for the establishment of subscription libraries but I argue for a new interpretation. The observation that a medical library was the first subscription library founded in Leeds in the eighteenth century raises the possibility that factors were at play in the decision to found these libraries other than those leisure purposes usually suggested by historians. I suggest that the Leeds libraries were founded to meet a range of practical purposes – professional, learned and industrial – as well as the leisure and other associated interests which have been discussed so widely in the prevailing literature.
3
Gauld, Craig. "The fantasy of the corroborative and transformative archive : the authority of archival beginnings." Thesis, University of Glasgow, 2010. http://theses.gla.ac.uk/1511/.
Full textAbstract:
What is the nature of the archive in the 21st century? What is the role of the archivist in a postmodern, electronic environment? To attain any absolute answers would be beyond the ability, or diplomacy, of any individual. Yet there are some questions, and subsequent dividing lines, which can be brought to the fore: • Is the archive a resting place for non-current records, a repository that provides the connection between inscription and preservation in order to ensure the veracity of the record as an authentic and reliability piece of evidence? • Should the archivist be distinct from the records manager? • Is the historical canon, if permitted to even use the term, a construct of the archive? If the answer is in the affirmative then does this legitimise the archivist in imparting overt value to a record/collection? • Is the archivist a custodian and keeper? • Should the archivist interact with wider societal needs and concerns? The ideal and idea of the archive and the archivist has become virtually unrecognisable from its early 20th century construct as questions such as these have been debated in the journals of archival science. The antiquated Jenkinsonian world-view has been dispensed with. The moral and physical defence of the archive is unsubstantial. Ensuring the preservation of the record and making it available to the public does not provide the archivist with a presence. Rather, the authority of archival beginnings has become the dominant, over-arching ideology. Through the advocacy of records continuum theorists and the proponents of postmodernism, we are to “stop rowing, start steering”. In order to be accountable, transparent, open, and representative, the archival profession is to control context and master reality. The archive is to define its own truth criteria. The archivist is an agent of accountability. The archivist is to openly negate his/her independent, neutral, non-political, non-ideological role: (1) There is an archive fever of audit culture. This is in response to the rise of the ‘consumer’ – “There is a risk, we’ll take care of it”. Continual monitoring, evaluation, and targets results in the record being a self-reflexive construct. Audit trails create a sense of truthfulness to the facts and of closeness to past reality. These perspectives have entered the archive. Perceived recordkeeping failures have made the archive unaccountable to wider society. The ‘right’ records are not reaching the archive. Records therefore must be programmed in advance by archivists working as records managers to produce acceptable outcomes. The archivist shapes the creation of the record. Archiving is auditing the recordkeeping systems of a record creating body. Archiving is the “active production of objectively truthful documents”. (2) Postmodernism sanctions a creative reconstruction of the past. The archive is to “fabricate metaphors…[tell] imaginings of history”. The archive overtly interprets the record and creates interfaces that reflect this interpretation and subjectivity, reifying cultural essentialism to appear representative of all elements of society. The archivist becomes a conscious participant in the construction and advancement of meaning. The perception of the user towards the records is moulded. The archive becomes a means of memory rather than memory itself. This thesis takes on what the author perceives as certain often rhetorical excesses of the records continuum theory and those of postmodernism. It engages on their terms, with their arguments, and with the interdisciplinary nature of today’s archival thinking. It shows that ‘traditional’ archival concepts and values are just as necessary and relevant today as in the supposedly homogenous and positivist society in which they arose. This thesis thus upholds the Jenkinsonian ideals for archives. However, it recognises the difficulty of achieving them, and that the proponents of postmodernism examined here do not intend to dispense with rigorous reasoning, balanced analysis, and truth seeking in favour of unrestrained ‘anything goes’ interpretations of records and archival concepts. Indeed, the author himself draws on leading postmodern thinkers such as Foucault and Derrida to develop his own socio-political analysis of audit records produced in the ‘audit culture’ of the past few decades. In so doing, the author hopes to show how postmodern analysis can be done in the spirit of the Jenkinsonian commitment to protection of evidential values through truth seeking. That said, the author believes that the archivist does not create life but holds the materials within its institution in a coma, awaiting the user to awake them from their perpetual slumber. This is a true re-assertion of archival value and responsibility. In caring more for a record’s corroborative power and transformative effect we have got too interested in the way we deliver what we do at the expense of what we deliver – engineering over content. Yet by acting responsibly the archive broadens perspectives and enlightens the individual. This is the responsible archival performance worth pursuing.
4
Fuchs, Thomas. "Bibliotheca Ilfeldensis: Die Bibliothek der ehemaligen Klosterschule Ilfeld." MVB, 2008. https://ul.qucosa.de/id/qucosa%3A71579.
Full text
5
Nale, Janet Yakubu. "Isolation and characterisation of temperate bacteriophages of the hypervirulent Clostridium difficile 027 strains." Thesis, University of Leicester, 2013. http://hdl.handle.net/2381/27918.
Full textAbstract:
Clostridium difficile 027 can be divided into several subclades which vary in their disease severity. Genomic studies of C. difficile 027 strains have established that they are rich in mobile genetic elements including prophages. Little is known about temperate bacteriophage carriage in C. difficile 027 clinical isolates. Therefore, this study was designed to induce and characterise temperate bacteriophages from C. difficile 027 subtypes’ clinical isolates as a first step to understanding their potential role in disease and diversity. Ninety-one C. difficile 027 clinical isolates were induced for prophage, and the bacteriophages present were characterised using transmission electron microscopy and pulsed-field gel electrophoresis. A correlation between phage morphology and subtype was established. Morphological and genetically distinct tailed bacteriophages belonging to Myoviridae and Siphoviridae were identified in 62 and three isolates, respectively. Dual phage carriage was observed in four isolates. There were inducible phage tail-like particles in all the isolates. The capacity of the two antibiotics norfloxacin and mitomycin C to induce prophages was compared and it was found that they induced specific prophages from C. difficile isolates. PCR assays targeting the capsid, holin and portal genes of the myoviruses were designed to examine molecular diversity of C. difficile myoviruses. Phylogenetic analysis of the genes sequences from ten ribotypes showed that all sequences found in the ribotype 027 strains were identical and distinct from other C. difficile ribotypes and other bacteria species. Sporulation which can be influenced by histidine kinase gene encoded by C. difficile phages was characterised in 41 isolates. The isolates sporulated within the first 96 h producing between 10[superscript 4] and 10[superscript 12] CFU/ml spores. The variation in sporulation characteristics did not correlate to the subtypes or prophage contents of the isolates examined. This study strongly suggests that phages and sporulation contribute to diversity, evolution and success of this pathogen.
6
Schneider, Ulrich Johannes. "Sammlungen, die Bibliothek, die Zukunft." Leipziger Universitätsverlag, 2012. https://ul.qucosa.de/id/qucosa%3A13034.
Full textAbstract:
In den letzten Jahren grassierte unter Geisteswissenschaftlern das Archivfieber: Man sucht, auch in der durch gedruckte Texte überlieferten Vergangenheit, nach Sammlungen und ihren inneren Zusammenhängen. Man möchte über bekannte Textzeugnisse hinausgehen, man erforscht Kontexte, die sich in der Zeit verfestigt haben und nun in allen Tiefendimensionen studierbar sind. Man tritt gewissermaßen aus den geistesgeschichtlichen Selbstverständlichkeiten
hinaus und nähert sich unbefangen dem, was man in anderen Formen
schon kennt. So werden auch Bibliotheken interessant, sobald man über die normalen Routinen der Bestandsabfragen und über die Erforschung einzelner Stücke hinausgeht. Welche Fragen kann eine Bibliothek beantworten, nachdem sie die Fragen der wissenschaftlichen Curiositas und der alltäglichen Neugier schon beantwortet hat? Das vom Archivfieber entzündete Interesse richtet sich auf Provenienzen, also auf Herkünfte von Einzelstücken bis zu ganzen Büchersammlungen, was auch immer in größere Sammlungen integriert wurde.
7
Schneider, Ulrich Johannes. "Universitätsbibliothek Leipzig." Leipziger Universitätsverlag, 2009. https://ul.qucosa.de/id/qucosa%3A13032.
Full textAbstract:
Die Universitätsbibliothek Leipzig ist zwar eines der ältesten Institute dieser Art in Deutschland. Ihre 466jährige Geschichte ist jedoch nur in Teilen erforscht. Der folgende Text fußt auf den Ergebnissen der bereits vorliegenden Publikationen und fokussiert zugleich die Darstellung auf die Dienstleistungsfunktion der Bibliothek für die Universität. Eine umfassendere historische Darstellung befindet sich in Vorbereitung.
8
Matook, Khaled Soliman. "The academic libraries of the future in Saudi Arabia and their manpower requirements." Thesis, Manchester Metropolitan University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270886.
Full text
9
Calixto, José António. "The educational roles of public libraries in Portugal : political and professional perceptions." Thesis, University of Sheffield, 2003. http://etheses.whiterose.ac.uk/14613/.
Full textAbstract:
This study examines the educational roles of public libraries in Portugal, as perceived by elected members and public librarians. The research was undertaken in 15 local authorities throughout the country, selected by purposeful sampling from the responses to a preliminary questionnaire. The methodology used a grounded theory approach and the core data were obtained via semi-structured interviews with 53 respondents. The data suggest that the respondents view public libraries as having well established roles in the fields of literacy, reading promotion and up to some extent, lifelong learning. Diverse sectors of the community are considered as beneficiaries of the library support to learning, including children and young people, higher education students, teachers and adult learners. The public library also helps vulnerable people overcome geographical, economic and age barriers to education. The evidence obtained by this study suggests that these roles are more relevant in a country such as Portugal that has generally low levels of literacy and poor socioeconomic indicators. The views of the respondents acknowledge this relevance, but differences of opinion emerge from the data suggesting some partial and limited opinions on the educational roles, especially the support for lifelong learning. This study suggests that several factors may influence the perceptions of the respondents. These factors include the socio-economic and educational context in which public libraries operate and a poor public perception of library roles, caused by the relative newness of public libraries in Portugal. Individual and local factors, such as the education and professional experience of the respondents and the size of the local authorities may also influence perceptions. The managerial and legal context is characterised by lack of legislation on public libraries and a traditionalist and bureaucratic organisational culture. The absence of an underlying philosophy on the roles of libraries in education is very apparent in the lack of research and publications in this field. A number of recommendations are put forward: legislation on public libraries, including on their educational roles, the publication of standards and guidelines, the increase of resources, especially staff and finance. Further research on the educational roles of public libraries is also recommended.
10
Klai, Amira. "Clostridium difficile : étude du processus de colonisation et d'hypervirulence de la souche épidémique 027." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00922985.
Full textAbstract:
Clostridium difficile est une bactérie entéropathogène responsable de diarrhées nosocomiales post-antibiotiques et de colites pseudomembraneuses. Ces dernières années, l'incidence et la gravité des infections à C. difficile ont significativement augmenté en Amérique et en Europe. Cette évolution semble être liée à l'émergence puis à la dissémination très rapide d'un clone particulièrement virulent de PCR-ribotype 027. Les facteurs de virulence majeurs de C. difficile sont les toxines TcdA et TcdB qui sont responsables des lésions intestinales. Cependant, l'étape de colonisation de l'intestin par la bactérie est considérée comme un pré-requis à l'infection. Afin de mieux comprendre les mécanismes d'hypervirulence de la souche 027, nous nous sommes focalisés sur l'étude du processus de colonisation intestinal de cette souche en le comparant à celui de la souche non épidémique 630∆erm. Dans un premier temps, nous avons étudié le rôle de la protéine de liaison à la fibronectine FbpA. La caractérisation in vitro et in vivo d'un mutant d'inactivation de fbpA, nous a permis de montrer l'implication de cette protéine dans le processus de colonisation de la souche non épidémique 630∆erm. La difficulté à obtenir un mutant dans la souche épidémique 027 R20291 ne nous a pas permis de comparer les propriétés adhésives de FbpA entre les deux souches. Dans un deuxième temps, nous avons étudié les caractéristiques des protéines flagellaires FliC, FliD, FlgE et MotB. Nous avons montré que les flagelles agissent en tant qu'adhésines chez la souche 027 et que ce rôle est moins important chez la souche 630∆erm. Nous avons également montré que les flagelles sont impliqués dans des processus cellulaires autres que l'adhésion et la colonisation. Selon une étude transcriptomique d'un mutant ∆FliC de la souche 027 R20291, il s'est avéré que la flagelline est aussi impliquée dans la production de toxines, la sporulation et dans l'adaptation de la bactérie aux conditions de stress. Une étude complémentaire serait nécessaire afin de mieux comprendre le système de régulation qui régi ces différents processus cellulaires.Finalement, nous avons effectué une analyse transcriptomique de la cinétique de colonisation in vivo de la souche 027. L'étude a révélé l'expression précoce des gènes de toxines et de sporulation au cours du processus d'infection. Elle nous a également permis d'identifier des gènes spécifiques à la souche 027 qui sont exprimés lors du processus infectieux. Ces gènes pourraient éventuellement être impliqués dans la virulence de C. difficile 027 et pourraient constituer de nouvelles pistes d'étude.
11
Barketi-Klai, Amira. "Clostridium difficile : étude du processus de colonisation et d’hypervirulence de la souche épidémique 027." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA114844/document.
Full textAbstract:
Clostridium difficile est une bactérie entéropathogène responsable de diarrhées nosocomiales post-antibiotiques et de colites pseudomembraneuses. Ces dernières années, l'incidence et la gravité des infections à C. difficile ont significativement augmenté en Amérique et en Europe. Cette évolution semble être liée à l'émergence puis à la dissémination très rapide d'un clone particulièrement virulent de PCR-ribotype 027. Les facteurs de virulence majeurs de C. difficile sont les toxines TcdA et TcdB qui sont responsables des lésions intestinales. Cependant, l’étape de colonisation de l’intestin par la bactérie est considérée comme un pré-requis à l’infection. Afin de mieux comprendre les mécanismes d’hypervirulence de la souche 027, nous nous sommes focalisés sur l’étude du processus de colonisation intestinal de cette souche en le comparant à celui de la souche non épidémique 630∆erm. Dans un premier temps, nous avons étudié le rôle de la protéine de liaison à la fibronectine FbpA. La caractérisation in vitro et in vivo d’un mutant d’inactivation de fbpA, nous a permis de montrer l’implication de cette protéine dans le processus de colonisation de la souche non épidémique 630∆erm. La difficulté à obtenir un mutant dans la souche épidémique 027 R20291 ne nous a pas permis de comparer les propriétés adhésives de FbpA entre les deux souches. Dans un deuxième temps, nous avons étudié les caractéristiques des protéines flagellaires FliC, FliD, FlgE et MotB. Nous avons montré que les flagelles agissent en tant qu’adhésines chez la souche 027 et que ce rôle est moins important chez la souche 630∆erm. Nous avons également montré que les flagelles sont impliqués dans des processus cellulaires autres que l’adhésion et la colonisation. Selon une étude transcriptomique d’un mutant ∆FliC de la souche 027 R20291, il s’est avéré que la flagelline est aussi impliquée dans la production de toxines, la sporulation et dans l’adaptation de la bactérie aux conditions de stress. Une étude complémentaire serait nécessaire afin de mieux comprendre le système de régulation qui régi ces différents processus cellulaires.Finalement, nous avons effectué une analyse transcriptomique de la cinétique de colonisation in vivo de la souche 027. L’étude a révélé l’expression précoce des gènes de toxines et de sporulation au cours du processus d’infection. Elle nous a également permis d’identifier des gènes spécifiques à la souche 027 qui sont exprimés lors du processus infectieux. Ces gènes pourraient éventuellement être impliqués dans la virulence de C. difficile 027 et pourraient constituer de nouvelles pistes d’étudeClostridium difficile is an enteropathogenic bacterium that causes post-antibiotic nosocomial diarrhea and pseudomembranous colitis. During the last decade, the incidence and the severity of C. difficile infections have significantly increased in America and Europe. This evolution seems to be related to the emergence and to the rapid dissemination of a particularly virulent clone of PCR-ribotype 027. The main virulence factors of C. difficile are the TcdA and TcdB cytotoxins which are responsible for intestinal lesions. However, the intestinal colonization by the bacterium is considered as an indispensible step for infection.To better understand the hypervirulence mechanisms of strain 027, we focused on the study of intestinal colonization process of this strain compared to the colonization process of the non-epidemic strain 630Δerm. First, we studied the role of the fibronectin binding protein FbpA. In vitro and in vivo characterization of a mutant FbpA showed the involvement of this protein in the colonization process of the non-epidemic strain 630Δerm. The difficulty of obtaining a mutant in the epidemic strain R20291 027 does not allow us to compare the adhesive properties of FbpA between the two strains.In a second step, we studied the characteristics of flagellar proteins FliC, FliD, FlgE and MotB. We showed that the flagella have a role in the adhesion and colonization of strain 027 and that this role is less important in strain 630Δerm. We also showed that flagella are involved in other cellular processes than adhesion and colonization. A transcriptomic study of a FliC mutant in 027 R20291 shows that flagellin is also involved in toxin production, sporulation and in the adaptation of bacteria to stress conditions. Further study should be performed to better understand the regulation system that governs these different cellular processes. Finally, we performed a transcriptomic analysis of the kinetic of in vivo colonization of the 027 R20291 strain. The study revealed a very early expression of toxin and sporulation genes during the first stages of the infection process. This analysis also allowed us to identify some genes, specific to 027 strains, which appeared regulated during the infection process. These genes could be involved in the virulence of C. difficile 027 strains and could provide new issues of study to better understand C. difficile virulence
12
Scholl, Heike. "Leseförderung in den Schulferien." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-39072.
Full textAbstract:
Für die Zeit der Sommerferien werden von Schulen und Bibliotheken Leseclubs ins Leben gerufen. Die Teilnehmer, Schülerinnen und Schüler ab der fünften Klasse, werden aufgefordert, in den Sommerferien drei Bücher von einer vorgegebenen Auswahl von hundert Titeln zu lesen. Der Inhalt wird in den mitwirkenden Bibliotheken abgefragt und im Leselogbuch bestätigt. Gleichzeitig können die Schüler eine Bewertung abgeben, wie Ihnen das Gelesene gefallen hat. Am Ende des Buchsommers erhalten die Teilnehmer bei der Abschlussparty ein Zertifikat für die erfolgreiche Teilnahme.
13
Steglich, Matthias [Verfasser], and Ulrich [Akademischer Betreuer] Nübel. "Evolutionsgenetik und Phylogeographie von Clostridium difficile Ribotyp 027 in Deutschland / Matthias Steglich ; Betreuer: Ulrich Nübel." Braunschweig : Technische Universität Braunschweig, 2017. http://d-nb.info/1175890553/34.
Full text
14
Martin, Melissa Jane. "Characterisation of the `agr' locus and naturally occurring membrane vessicles in `Clostridium difficile' 027 strains." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590512.
Full text
15
Johansson, Charlotta. "Safety and mobility of children crossing streets as pedestrians and bicyclists." Doctoral thesis, Luleå, 2004. http://epubl.luth.se/1402-1544/2004/027.
Full text
16
Al-Mahri, Bakhit Ahmed Rajhit. "An evaluation of the effectiveness of the learning resource centres in the colleges of education in Oman." Thesis, University of Glasgow, 2003. http://theses.gla.ac.uk/4847/.
Full textAbstract:
This study reports on an investigation of the effectiveness of the Learning Resource Centres (LRCs) in the Colleges of Education in Oman. It considers the aims of the LRCs/libraries and explored the extent to which the LRCs achieve their aims and identified the defects which represent obstacles to improving the LRCs. The extent to which the LRCs support the Colleges of Education to achieve their aims is also explored. Accordingly, this thesis examines the effectiveness of the LRCs and leads to recommendations, which if implemented, will improve the LRCs for the users. In order to achieve the research purposes the study surveys the LRCs in the Colleges of Education in Oman. The survey includes observation of all six LRCs, responses to questionnaires from 140 academics and 436 students and interviews with 24 employees from the staff ofLRCs. In consideration of the fact that the Ministry of Higher Education in Oman (MOHE) tries to benefit from the Canadian experience in LRCs/libraries, interviews were conducted with nine employees working in LRCs/libraries at six Canadian Universities. The study indicates that, in general, the LRCs have satisfactory factors such as the provision of resources, accessibility, support from personnel to users, training of users to develop their skills and increase the utilisation of facilities. Consequently these enhance the possibility of achieving the aims of the LRCs as well as supporting the Colleges to attain their aims. The availability of the previous factors also indicates to the reasonable effectiveness of the LRCs. On the other hand, the findings of the study consider that the main obstacles to improving the LRCs are: centralisation of acquisition of human and material resources at the MOHE, space, policy, and the incomplete classification system and catalogue. Finally the study proposes recommendations which can overcome the identified obstacles and improve the effectiveness of the LRCs in the Colleges of Education in Oman.
17
Sekulovic, Ognjen. "Étude de l'impact des prophages sur la biologie de Clostridium difficile." Mémoire, Université de Sherbrooke, 2010. http://savoirs.usherbrooke.ca/handle/11143/4049.
Full textAbstract:
La bactérie Clostridium difficile est maintenant considérée comme un pathogène majeur responsable d'infections nosocomiales en Amérique du Nord et en Europe. De plus, l'émergence de souches hypervirulentes, telle la souche NAP1/027 responsable de récentes épidémies, est un phénomène inquiétant. Un enjeu crucial au cours des prochaines années sera de mieux comprendre les mécanismes de virulence et d'évolution de C. difficile. Les bactériophages (c.-à-d. des virus bactériens, ou phages) sont des joueurs clés dans l'évolution de la plupart des bactéries, pathogènes ou non. Les données concernant l'impact des phages sur C. difficile sont très limitées. Par contre, deux études récentes démontrent que les phages semblent influencer la virulence de C. difficile en altérant la production de toxines TcdA et TcdB. L'objectif de mes travaux de recherche est donc d'étudier au niveau microbiologique et moléculaire les phages de C. difficile et de démontrer leur impact sur l'évolution et la virulence de ce pathogène. Dans ce contexte, plusieurs phages ont été induits à partir d'isolats cliniques de C. difficile. Dans cette collection, un phage en particulier, le (pCD38-2, a été choisi pour la caractérisation subséquente dû à sa divergence génomique par rapport aux autres phages et à sa capacité d'infecter la grande majorité des souches ayant le ribotype hypervirulent (027). Ces caractéristiques uniques ont justifié le séquençage complet de son génome. Par contre, aucun facteur de virulence évident n'a été identifié. À l'opposé, une analyse bio-informatique a permis l'identification d'une région spécifique comportant plusieurs gènes de conversion lysogénique potentiels. L'impact de ces gènes sur la virulence bactérienne reste à être déterminé. De plus, lorsqu'on introduit le phage cpCD38-2 dans la souche sensible CD274, on observe une accumulation plus rapide et plus grande des toxines après 48h dans le surnageant de la culture. Ce phénomène a été confirmé avec des tests ELISA sur des réplicas biologiques indépendants ainsi que par un immunodosage avec anticorps spécifiques aux deux toxines. Par ailleurs, une étude transcriptionelle par PCR en temps réel a permis de constater que le phage (pCD38-2 influence également l'expression des gènes tcdA et tcdB dans le temps. Par contre, l'effet du phage cpCD38-2 est variable lorsqu'on l'introduit dans d'autres souches de C. difficile. Donc, les résultats de nos travaux indiquent que certains phages auraient un impact sur la virulence de C. difficile en altérant la production et la transcription des gènes de toxines. Nos données laissent toutefois sous-entendre que cet effet peut varier selon les souches de C. difficile. [Symboles non conformes]
18
Schneider, Ulrich Johannes. "Sammlungen, die Bibliothek, die Zukunft." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-157024.
Full textAbstract:
In den letzten Jahren grassierte unter Geisteswissenschaftlern das Archivfieber: Man sucht, auch in der durch gedruckte Texte überlieferten Vergangenheit, nach Sammlungen und ihren inneren Zusammenhängen. Man möchte über bekannte Textzeugnisse hinausgehen, man erforscht Kontexte, die sich in der Zeit verfestigt haben und nun in allen Tiefendimensionen studierbar sind. Man tritt gewissermaßen aus den geistesgeschichtlichen Selbstverständlichkeiten
hinaus und nähert sich unbefangen dem, was man in anderen Formen
schon kennt. So werden auch Bibliotheken interessant, sobald man über die normalen Routinen der Bestandsabfragen und über die Erforschung einzelner Stücke hinausgeht. Welche Fragen kann eine Bibliothek beantworten, nachdem sie die Fragen der wissenschaftlichen Curiositas und der alltäglichen Neugier schon beantwortet hat? Das vom Archivfieber entzündete Interesse richtet sich auf Provenienzen, also auf Herkünfte von Einzelstücken bis zu ganzen Büchersammlungen, was auch immer in größere Sammlungen integriert wurde.
19
Sirard, Stéphanie. "Analyse génotypique et phénotypique d'isolats cliniques de Clostridium difficile et comparaison en fonction de la sévérité des symptômes." Mémoire, Université de Sherbrooke, 2011. http://hdl.handle.net/11143/5547.
Full textAbstract:
Clostridium difficile est la principale cause de diarrhées nosocomiales liées à la prise d'antibiotiques. La souche hypervirulente NAP1/027 est apparue récemment et a causé de nombreuses épidémies en Amérique du Nord et en Europe. On considère généralement que cette souche produit plus de toxines, sporule davantage, provoque des infections plus sévères menant à des complications et est souvent associée aux cas de récurrence. Toutefois, des études récentes ont montré des données contradictoires à ce sujet. L'objectif de mes travaux de recherche est donc de déterminer si l'issue clinique des infections à C. difficile (ICD) peut être prédite en fonction du génotype et de certains phénotypes bactériens associés à la virulence, comme la production de toxines et la sporulation. Pour ce faire, 21 isolats cliniques associés à des ICD de sévérité différente (légère à modérée, sévère, compliquée) ont été caractérisés par des méthodes de typage courantes, incluant le ribotypage par PCR, le typage des répétitions en tandem, l'analyse de loci multiples de répétitions en tandem polymorphe, la détection des toxines A, B et CDT, ainsi que le séquençage du gène tcdC. Les taux de sporulation et la production des toxines A et B ont aussi été évalués in vitro, de même que la résistance des isolats à certains antibiotiques. La mobilité, la sensibilité des isolats à certains bactériophages et leur contenu en prophages ont aussi été étudiés. Les résultats de mes travaux démontrent que les méthodes de typage utilisées ne permettent pas de prévoir avec certitude le phénotype bactérien ni de prédire la sévérité des ICD. En effet, les souches NAP1/027 peuvent autant provoquer des ICD non-sévères que mener à des complications. Le phénotype n'est pas non plus nécessairement un indice de la sévérité. Les souches NAP1/027 produisent généralement plus de toxines, mais ne possèdent pas forcément la capacité de sporulation qu'on leur attribue généralement. Par conséquent, les généralisations à propos des souches NAP1/027 devraient être évitées.
20
Swirtun, Linda R. "Anterior cruciate ligament injury : factors affecting selection of treatment and intermediate outcome /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7357-027-3/.
Full text
21
Werme, Martin. "On natural and drug-induced reward : genetic, biochemical and behavioral comparisons /." Stockholm : [Karolinska Univ. Press], 2001. http://diss.kib.ki.se/2001/91-7349-027-X/.
Full text
22
Tang, Lisa Eng. "Age-associated hepatic drug transporter expression and its implications for pediatric pharmacotherapy." View the abstract Download the full-text PDF version, 2007. http://etd.utmem.edu/ABSTRACTS/2007-027-Tang-Index.html.
Full textAbstract:
Thesis (Ph.D. )--University of Tennessee Health Science Center, 2007.Title from title page screen (viewed on June 19, 2008). Research advisor: Bernd Meibohm, Ph.D. Document formatted into pages (xiv, 100 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 96-100).
23
Nooh, Mohammed Mostafa. "Biochemical and immunological mechanisms underlying differential interaction of superantigens with host immunogenetic factors in streptococcal sepsis." View the abstract Download the full-text PDF version, 2008. http://etd.utmem.edu/ABSTRACTS/2008-027-Nooh-index.html.
Full textAbstract:
Thesis (Ph.D )--University of Tennessee Health Science Center, 2008.Title from title page screen (viewed on Sept. 17 2008). Research advisor: Malak Y. Kotb, Ph.D. Document formatted into pages (xvii, 189 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 161-189).
24
Robinson, Bridget K. "Determinants of physical activity behavior and self-efficacy for exercise among African American women." View the abstract Download the full-text PDF version, 2009. http://etd.utmem.edu/ABSTRACTS/2009-027-Robinson-index.htm.
Full textAbstract:
Thesis (M.S.)--University of Tennessee Health Science Center, 2009.Title from title page screen (viewed on September 18, 2009). Research advisor: Mona N. Wicks, Ph.D. Document formatted into pages (x, 85 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 63-71).
25
Capitanio, Lara. "Foglio 027 Bolzano. Studio petrografico delle vulcaniti permiane del settore Val di Tires – Passo Nigra, Alta Val d’Ega, Bolzano." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/14458/.
Full textAbstract:
Il presente lavoro di tesi si inquadra nel programma di rilevamento geologico del Foglio 027 Bolzano, nell’area della Val di Tires – Passo Nigra, Alta Val d’Ega (Bolzano), la cui realizzazione è in corso a cura della Provincia Autonoma di Bolzano, nell’ambito del progetto CARG.
Durante la campagna di rilevamento sono stati prelevati 33 campioni presso Tires, in Alta Val d’Ega, appartenenti alle vulcaniti permiane del Gruppo Vulcanico Atesino (GVA), 18 dei quali sono stati sottoposti ad analisi ottico-petrografica e chimica in XRF.
I campioni sono stati prelevati dalle tre principali formazioni geologiche affioranti nell’area: la Formazione di Gargazzone (IGG), la Formazione di Cornedo (COR) e la Formazione di Ora (ORA).
Dalle analisi è emerso che i campioni prelevati dalla Formazione di Gargazzone risultano di composizione riodacitica, quelli della Formazione di Cornedo hanno composizione andesitica e andesitico-dacitica, quelli della Formazione di Ora hanno composizione riolitica e riodacitica.
Sono state distinte tre litofacies all’interno della Formazione di Ora: una litofacies basale, caratterizzata da un’elevata concentrazione di componenti litiche; una litofacies intermedia, decisamente più massiccia ed omogenea, che presenta al suo interno sporadici corpi lenticolari di ignimbriti ricche in pomici; una litofacies di tetto, ricca in pomici.
Generalmente le ignimbriti della Formazione di Ora si caratterizzano per la composizione riolitica ricca in sanidino, ma la presenza di ignimbriti di composizione riodacitica all’interno della formazione e precisamente nell’area di studio, si può imputare alla modificazione della composizione mineralogica e chimica originaria a causa dei fenomeni metasomatici, particolarmente intensi lungo il bordo calderico.
Sono stati inoltre prelevati cinque campioni che tagliano le formazioni affioranti, due dei quali hanno composizione riolitica, due hanno composizione basaltica e uno ha composizione alcali-basaltica.
26
Gemein, Stefanie [Verfasser]. "Etablierung eines Testverfahrens zur Prüfung sporizider Flächendesinfektionsmittel: mit dem Schwerpunkt Clostridium difficile Ribotyp 027 / Stefanie Gemein. Mathematisch-Naturwissenschaftliche Fakultät." Bonn : Universitäts- und Landesbibliothek Bonn, 2011. http://d-nb.info/1017217394/34.
Full text
27
Schneider, Ulrich Johannes. "Über die Rolle von Bibliotheken in einer digitalisierten Welt." Klartext-Verl, 2010. https://ul.qucosa.de/id/qucosa%3A13056.
Full textAbstract:
Man denkt sich in der Zeit der digitalen Revolution die Bibliotheken als besonders betroffen von den technischen und kulturellen Umwälzungen, die das Internet mit sich bringt. Das ist richtig. Schon sind fast alle Kataloge online und damit weltweit auskunftsfähig. Bald sind auch große Teile der Bestände unserer Buchkultur digital erreichbar. Was erwartet uns im Jahr 2020? Lösen sich Bibliotheken in Webseiten auf? Wird alles Wissen, zu dem sie Zugang gewähren, nur noch elektronisch kommuniziert? Wenn wir genau wüssten, worin die Attraktivität von Bibliotheken heute liegt, fiele der Blick in die Zukunft leicht.
28
Schneider, Ulrich Johannes. "Universitätsbibliothek Leipzig." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-157007.
Full textAbstract:
Die Universitätsbibliothek Leipzig ist zwar eines der ältesten Institute dieser Art in Deutschland. Ihre 466jährige Geschichte ist jedoch nur in Teilen erforscht. Der folgende Text fußt auf den Ergebnissen der bereits vorliegenden Publikationen und fokussiert zugleich die Darstellung auf die Dienstleistungsfunktion der Bibliothek für die Universität. Eine umfassendere historische Darstellung befindet sich in Vorbereitung.
29
Rambelli, Daniele. "Studio petrografico delle vulcaniti permiane nell’area di Ponte Gardena – Barbiano (BZ)." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019.
Find full textAbstract:
Il lavoro di questa relazione di laurea consiste nello studio ottico, chimico e petrografico di 17 campioni di vulcaniti permiane appartenenti al gruppo vulcanico atesino (GVA). Il lavoro sperimentale è consistito nello studio petrografico in sezione sottile e geochimico dei campioni, con lo scopo di ottenere un'analisi precisa e una classificazione dei litotipi. Il lavoro di rilevamento geologico effettuato sulle vulcaniti permiane del settore Nord del Foglio 027-Bolzano richiede un accurato studio mineralogico-petrografico e geochimico dei campioni, mirato alla loro classificazione. Come evidenziato dal diagramma TAS, le rocce vulcaniche permiane affioranti in quest’area sono affette da profondi fenomeni metasomatici che hanno modificato la mineralogia di queste rocce e solo lo studio petrografico è in grado di consentirne la classificazione e la correlazione con le altre vulcaniti permiane.
I risultati di questo lavoro possono essere così riassunti:Il gruppo più numeroso di campioni appartiene alla Formazione di Sarentino. Questi campioni sono particolarmente alterati e i dati di campagna hanno ancora un relativo margine di incertezza. Questo è evidente dal diagramma TAS, in cui i punti rappresentativi dei campioni sono estremamente dispersi. Nel diagramma di W&F sono invece raggruppati nel campo delle daciti. I due campioni della formazione di Avelengo (AGO) cadono nel campo delle daciti (diagramma TAS) e a cavallo fra daciti e trachiandesiti (diagramma W&F). Il campione della formazione di ORA1 – Membro di Predonico è il più ricco in silice, in accordo con i dati di letteratura che indicano per gli eventi finali composizioni acide.
30
Schneider, Ulrich Johannes. "Über die Rolle von Bibliotheken in einer digitalisierten Welt." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-158226.
Full textAbstract:
Man denkt sich in der Zeit der digitalen Revolution die Bibliotheken als besonders betroffen von den technischen und kulturellen Umwälzungen, die das Internet mit sich bringt. Das ist richtig. Schon sind fast alle Kataloge online und damit weltweit auskunftsfähig. Bald sind auch große Teile der Bestände unserer Buchkultur digital erreichbar. Was erwartet uns im Jahr 2020? Lösen sich Bibliotheken in Webseiten auf? Wird alles Wissen, zu dem sie Zugang gewähren, nur noch elektronisch kommuniziert? Wenn wir genau wüssten, worin die Attraktivität von Bibliotheken heute liegt, fiele der Blick in die Zukunft leicht.
31
Ribeiro, Paulo Leonardo Lima. "Efeito da glicerina residual do biodiesel e de estirpes microbianas (Cupriavidus necator IPT 027 e Burkholderia cepacia IPT 438) na produção, propriedades e composição de copolímeros de polihidroxialcanoatos." Universidade Federal da Bahia. Escola Politécnica, 2012. http://repositorio.ufba.br/ri/handle/ri/18621.
Full textAbstract:
Submitted by LIVIA FREITAS (livia.freitas@ufba.br) on 2016-01-22T15:06:18Z
No. of bitstreams: 1
dissertacao_mestrado_andrews-sobral.pdf: 12939498 bytes, checksum: 704a2ed85ace914b87b98cfe77a6e38c (MD5)Approved for entry into archive by Uillis de Assis Santos (uillis.assis@ufba.br) on 2016-02-15T21:52:36Z (GMT) No. of bitstreams: 1 dissertacao_mestrado_andrews-sobral.pdf: 12939498 bytes, checksum: 704a2ed85ace914b87b98cfe77a6e38c (MD5)
Made available in DSpace on 2016-02-15T21:52:37Z (GMT). No. of bitstreams: 1 dissertacao_mestrado_andrews-sobral.pdf: 12939498 bytes, checksum: 704a2ed85ace914b87b98cfe77a6e38c (MD5)
Os polihidroxialcanoatos (PHAs) são poliésteres produzidos por um grande número de estirpes bacterianas, em condições de crescimento limitante. Estes polímeros são completamente biodegradáveis e, por conseguinte, materiais alternativos para fins de substituição dos temoplásticos sintéticos. No entanto, os PHAs, ainda, não têm sido capazes de competir com as resinas convencionais, devido ao elevado custo de processo. Uma forma possível de reduzir os custos de produção é a utilização de fontes de carbono mais baratas, como os coprodutos da indústria do biodiesel. Deste modo, estirpes de Cupriavidus necator IPT 027 e Burkholderia cepacia IPT 438 foram utilizadas, em estudo, a fim de sintetizar PHAs a partir de distintas glicerinas residuais do biodiesel (GRBs) derivadas, por sua vez, do processamento do biodiesel de soja (GRB I), óleos e gorduras residuais (GRB II) e mamona (GRB III). Diferentes variáveis foram mantidas constantes durante a produção de PHA, obtendo-se um percentual máximo de extração de 71,07 %, quando se fez uso da cepa Cupriavidus necator IPT 027 em cultivo com GRB II. As análises de CG-MS revelaram copolímeros de PHAs com hidroxiésteres de cadeia curta (3HB) e de cadeia média (3HTD, 15HPD e 11HHD), com distintas frações em %mol. Tais resultados relacionam-se com o meio de cultivo, as altas massas moleculares obtidas (552 kDa a 8240 kDa), as temperaturas de fusão (139,8 ºC a 175,9 ºC) e os graus de cristalinidade verificados por DRX (35,92 % a 66,07 %) e DSC (33,30 % a 57,80 %). Além disso, observou-se uma versatilidade da cepa Burkholderia cepacia IPT 438 perante as fontes de carbono estudadas, principalmente no que concerne às propriedades dos biopoliésteres. Portanto, majoritariamente, os biopolímeros produzidos obtiveram, segundo a literatura, propriedades aplicáveis em nível industrial, porém torna-se fundamental o controle otimizado do processo de cultivo, a fim de potencializar a produção e propriedades de copolímeros de PHAs, adequando-os as mais diversas aplicações tecnológicas.
32
Кириленко, Поліна Андріївна, and Валентин Олександрович Бутович. "Електронні бібліотеки: проблеми створення та перспективи розвитку." Thesis, Національний авіаційний університет, 2021. https://er.nau.edu.ua/handle/NAU/50510.
Full textAbstract:
1. Шрайберг. Я. Л. Основные положения и принципы разработки автоматизированных библиотечно-информационных систем и сетей: учеб. практ. пособие. изд. 2-е, испр. и доп. –М.: Либерия, 2001. –102 с
2. Lesk, Michael. Understanding Digital Libraries. Second Ed. Morgan Kaufmann Publisher, 2010The article deals with the generalization of existing research experience. Problems of creation, development and functioning of the electronic library as a component modern information-educational environment. The approaches to definition are considered the notion of "electronic library". The purpose of creating, specific features are determined, functional capabilities, basic functions of the electronic library.
У статті здійснено узагальнення існуючого досвіду дослідження проблем створення, розвитку та функціонування електронної бібліотеки як складової сучасного інформаційно-освітнього середовища. Розглянуто підходи до визначення поняття «електронна бібліотека». Визначено мету створення, специфічні особливості, функціональні можливості, основні функції електронної бібліотеки.
33
Hazel, Susan Jane. "Effects of treatment with IGF-I, GH and IGF-2 plus GH in a rat model of chronic renal failure /." Title page, contents and abstract only, 1995. http://web4.library.adelaide.edu.au/theses/09PH/09phh429.pdf.
Full text
34
Drost, Vincent. "Le monnayage de l'empereur Maxence (306-312 ap. J. -C. ) et l'histoire politique et économique de la fin de l'époque tétrarchique." Paris 1, 2011. http://www.theses.fr/2011PA010528.
Full textAbstract:
L'abondant monnayage frappé dans les ateliers contrôlés par Maxence (Carthage, Aquilée, Ticinum, Rome et Ostie) contribue de manière fondamentale à la connaissance de ce règne. Reflet du discours officiel de l'empereur, il offre un contrepoint aux jugements négatifs diffusés par la propagande constantinienne après la bataille du Pont Milvius. La présente étude se fonde sur un catalogue qui rassemble près de 5000 monnaies, dont plus de 1000 sont illustrées. Un corpus des rares monnaies d'or et d'argent est proposé. Quant au monnayage de bronze argenté, surabondant, il figure sous la forme d'un catalogue des types. Sur cette base, le classement des émissions monétaires est précisé de manière significative, ce qui ouvre la voie à une meilleure connaissance de certains aspects du règne. Le système monétaire maxentien est un système fort qui fut mis en place dans le cadre d'une autarcie économique presque complète. La numismatique, associée aux autres types de documents, permet de préciser certaines dates-clés (élévation de Maxence à l’ Augustat, reconquête de l’ Afrique, etc. ). Elle illustre aussi l'évolution de la politique diplomatique de Maxence, entre jeux d'alliances et rivalités, collégialité et indépendance. L'iconographie monétaire maxentienne, à la fois originale et traditionnelle, se situe en rupture avec les principes tétrarchiques pour marquer l'attachement de Maxence à la Romanitas.
35
Koop, Ulrike. "Wertzumessung für Öffentliche Bibliotheken." Doctoral thesis, Humboldt-Universität zu Berlin, 2017. http://dx.doi.org/10.18452/18125.
Full textAbstract:
Ziel dieser Arbeit ist die Ermittlung des ökonomischen Wertes einer Öffentlichen Bibliothek in einer deutschen Mittelstadt. Dabei werden die Wertschätzung beeinflussende Faktoren identifiziert und die Einschätzungen der Bevölkerung (Bibliotheksnutzer und Nicht-Nutzer) mit der der politischen und administrativen Vertreter kontrastiert.
Im theoretischen Teil wird der Forschungsstand zur Wert- und Wirkungsmessung dargelegt und in den Kontext der wirkungsorientierten Verwaltungsführung gestellt. Außerdem wird das Konzept der Lebensstile erläutert.
Im empirischen Hauptteil wird eine schriftliche Befragung zur ökonomischen Wertschätzung der Stadtbibliothek Melle ausgewertet. Zwei parallele Umfragen richteten sich zum einen an Einwohner der Stadt Melle und zum anderen an politische und administrative Vertreter. Neben der ökonomischen Wertzumessung, ausgedrückt als Zahlungsbereitschaft (Anwendung der Kontingenten Bewertungsmethode), stehen die Aspekte Lebensstil-Typen nach Gunnar Otte, Bibliotheksnutzung, sowie die Stellung im Familien-/Lebenszyklus als beeinflussende Faktoren im Mittelpunkt der Auswertung. Die geäußerten Zahlungsbereitschaften der Bevölkerung und der Politiker werden verglichen.
Es wird eine Relation von Zahlungsbereitschaft zu „Ergebnis je Einwohner“ (finanzbuchhalterische Kennzahl) als Indikator für die Wertschätzung gebildet.The aim of this study is to determine the economic value of a public library in a medium-sized town in Germany. The factors influencing the value must first be identified and the population’s (both library users and non-users) appreciation must be compared with those of their political and administrative representatives. In the theoretical section of this study the current state of research in value and impact assessment will be explained and presented within the context of impact-oriented administration (New Public Management). The concept of lifestyles will also be explained. The main, empirical section of the study concentrates on the assessment of a written questionnaire (mail survey) on the economic value of the Melle Public Library. Two parallel questionnaires were conducted; one for the population of the city of Melle and one for their political and administrative agents. In addition to the economic rating of the library, expressed as willingness-to-pay (under application of the contingent valuation method) at the core of the assessment, the analysis focuses on the aspects of lifestyle types according to Gunnar Otte, library use and position within the family or life cycle as influencing factors. The expressed willingness-to-pay of the population will be directly compared with that of the politicians. A ratio of willingness-to-pay and the result-per-resident (an economic value) will be generated and thereby an indicator of value determined.
36
Tournieroux, Anne. "Les bibliothèques privées en France et en Italie à la fin du Moyen Âge (1400-1520)." Thesis, Paris 1, 2017. http://www.theses.fr/2017PA01H103.
Full textAbstract:
Cette thèse a pour objet l’étude comparative des bibliothèques de laïcs et de clercs du nord de la France et de l’Italie septentrionale entre 1400 et 1520. Les rapports entre les territoires français et italien ne sont plus à démontrer, marqués pour le début de notre période par la résolution progressive du Grand Schisme et, pour la fin, par les guerres d’Italie menées entre 1494 et 1516. Au cours du quinzième siècle et jusqu’au début du seizième siècle, des phénomènes culturels de premier ordre tel que la diffusion de l’humanisme et, sur le plan matériel, l’invention de l’imprimerie se diffusent dans l’Europe entière. Nous avons choisi de nous intéresser à des catégories «traditionnelles» de possesseurs comme les membres du clergé séculier, mais aussi à de nouvelles catégories émergentes de possesseurs, notamment la bourgeoisieThis thesis aims at the comparative study of libraries of laity and clerics in the north of France and northern Italy between 1400 and 1520. The relations between the French and Italian territories are no longer to be demonstrated, marked for the beginning of our period by the progressive resolution of the Great Schism and, for the end, by the Italian wars between 1494 and 1516. In the fifteenth century and up to the beginning of the sixteenth century, cultural phenomena of the first order such as dissemination of humanism and, on the material level, the invention of printing spread throughout Europe. We have chosen to focus on "traditional" categories of possessors such as the secular clergy, but also to emerging categories of possessors, including the bourgeoisie
37
Hodgson, John. "Class acts : the twenty-fifth and twenty-sixth earls of Crawford and their manuscript collections." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/class-acts-the-twentyfifth-and-twentysixth-earls-of-crawford-and-their-manuscript-collections(3ed36c16-23f9-4b9c-85d5-21070eea9984).html.
Full textAbstract:
Throughout Victoria's reign, Lord Lindsay and his son Ludovic, respectively twenty-fifth and twenty-sixth earls of Crawford, created one of the largest private libraries ever assembled in Britain. The Bibliotheca Lindesiana included some six thousand manuscripts, which Ludovic sold to Enriqueta Rylands in 1901 for £155,000. The principal problematic that I address in this thesis is: Why did the earls of Crawford invest vast amounts of financial and cultural capital in this endeavour? In other words, what factors - both structural and specific - led to the formation of the library, what purposes did it serve, and what roles did its manuscript components in particular perform? Other questions include: How - and how successfully - did Lindsay and Ludovic maintain physical and intellectual control over the rapidly growing library? How did they position themselves within networks of connoisseurship and collecting in Victorian Britain? How was the formation of the Oriental manuscript collections connected with Lindsay's interest in racial classification and with wider racial discourses? And how did the library reflect and reinforce Lindsay's identity as a gentleman-scholar? Previous studies of this and other manuscript collections have adhered to an antiquarian, bio-bibliographical model, focusing on the detailed matter and mechanisms of collecting, rather than exploring the socio-cultural and epistemological contexts of their development. This thesis, by contrast, constitutes the first extended application of cultural theory to a manuscript collection, or indeed to any private library, in the nineteenth century. I combine close archival work with Bourdieu's concepts of field, capital and habitus to reveal the complex structuration and signification of the library, and to investigate the imbrication between the earls' personal agency and wider forces operating upon the library. My examination of the Bibliotheca Lindesiana has uncovered several key issues and themes hitherto unexplored in this or any other major private library of the nineteenth century. First, I argue that the reasons for the library's development reside principally in various forms of classification, which preoccupied Lindsay and reflected wider societal trends and taxonomies: the classification of libraries and the ramification of knowledge; Lindsay's deployment of the library to corroborate his and his family's social and cultural distinction (i.e. social classification); and an interest in racial classification, which reflected Orientalist discourses associated with imperialism. Secondly, while the dispersal of aristocratic collections in the late nineteenth and early twentieth centuries is a familiar trope, this study is the first to contextualize the decline of a private library within the struggle between the aristocracy and the bourgeoisie. Finally, this is the first examination of the impact of professionalization upon private as opposed to public libraries, revealing the tensions between amateur traditions and growing professionalism and specialization in the nineteenth century. I thus 'read' through the library some of the wider socio-economic and cultural issues operating in Victorian Britain and its empire.
38
Diouf, François Malik. "Les ressources numériques dans l'enseignement supérieur sénégalais : état des lieux et étude prospective." Thesis, Dijon, 2014. http://www.theses.fr/2014DIJOL042/document.
Full textAbstract:
C’est dans un contexte de pauvreté ou d’exclusion informationnelle, que la diffusion massive des outils informatiques et technologiques dans les bibliothèques de l’enseignement supérieur sénégalais, répond à un urgent besoin de transformation et d’amélioration des modes de fonctionnement et de modernisation des services offerts aux différents publics, notamment les étudiants. Actuellement, dans la quasi-totalité des bibliothèques de recherche et d’étude des universités du Sénégal, se développent des activités de numérisation qui ont culminé avec l’essor de l’Internet. Cette situation a engendré un véritable effet amplificateur des ressources numériques, par la mise en place de moyens de création, un accroissement des accès et le partage de l’information scientifique et technique dans les établissements d’enseignement supérieur. En tant que véritables vecteurs de transformation des usages et des pratiques documentaires des usagers dans les bibliothèques de l’enseignement supérieur du Sénégal, le développement des technologies de l’information et de communication, et la croissance des ressources numériques, vont inévitablement bouleverser les rapports traditionnels des étudiants aux bibliothèques. L’objectif de la présente thèse, est, dès lors, d’étudier la transformation de la professionnalité des bibliothécaires, la culture informationnelle des étudiants, et les usages qu’ils font réellement des ressources numériques, au regard des contextes socioculturel, politique, économique et sociotechnique du Sénégal, dans un contexte de société de l’information en construction. Ainsi, pourrons-nous, à travers cette étude, arriver à faire une analyse prospective consacrée au développement et à l’émergence des bibliothèquesIt is in the context of poverty or information exclusion that the massive dissemination of information and technology tools in Senegalese academic libraries responds to an urgent need for transformation and improvement of operational modes as well as modernization of services for different audiences, in particular students. Currently, in almost all academic and research libraries of Senegal digitization activities that crossed the rise of the Internet are being developed. This has created a real increasing effect of digital resources, by the establishment of means of creation and by expansion of access and of sharing of scientific and technical information in higher education institutions. The development of information technology and communication - the true vectors of documentary practices among Senegalese academic libraries users – together with the growth of digital resources, will inevitably turn the traditional relationship between students and libraries upside down. The objective of this thesis is, therefore, to study the transformation of the librarians’ profession, information culture of students, and their use of digital resources, with regard to sociocultural, political, economic, and sociotechnical contexts of Senegal; and in the context of the information society under construction. Thus, through this study, a prospective analysis devoted to the development and the emergence of libraries can be constructed
39
Malosse, Pierre-Louis. "Libanios, discours LIX : texte, traduction et commentaire." Montpellier 3, 1998. http://www.theses.fr/1998MON30047.
Full textAbstract:
L'eloge des empereurs constance et constante fils de constantin, est le premier discours compose par libanios, a nicomedie entre 344 et 348 apres j. -c. Il n'avait pas ete reedite depuis les travaux de forster au debut du siecle, et jamais traduit en francais. C'est un document historique d'un grand interet non seulement sur le regne des deux freres, periode pour laquelle les sources sont rares, mais aussi sur constantin. Il offre un point de vue a la fois traditionnel et personnel sur ce que pouvaient etre l'empereur, l'empire et les barbares (en particulier les francs et les perses) pour un sophiste grec de l'antiquite tardive. Dans ce modele de << basilikos logos >>, solennel, brillant mais aussi relativement concret, libanios a mis en oeuvre tous ses talents d'invention, de disposition et d'elocution, deja pleinement maitrises : connaissant parfaitement les regles scolaires, il n'en est pas pour autant l'esclave et son discours, loin de la gratuite purement rhetorique, exprime une veritable pensee morale et politique.
40
Bruhat, Marie-Odile. "Les Carmina Figurata de Publilius Optatianus Porfyrius : la métamorphose d'un genre et l'invention d'une poésie liturgique impériale sous Constantin." Paris 4, 1999. http://www.theses.fr/1998PA040320.
Full textAbstract:
Optatianus Porfyrius renouvelle le genre du poème figure alexandrin (technopaegnia). Ses poèmes carres font apparaitre, grâce à d'ingénieux versus intexti, un dessin intérieur : figures géométriques, inscriptions, figures emblématiques. Cette poésie figurée emprunte au domaine de l'épigraphie (jeux sur les dispositions de lettres et acrostiches), des arts décoratifs (motifs empruntes aux mosaïques) et des mathématiques (combinatoire et multiplication des possibilités de lecture). Pour décrire sa technique, le poète recourt au vocabulaire du tissage. Ses poèmes illustrent visuellement la conception du texte comme résultat d'un entrelacement. La métaphore du tissage appelle aussi la comparaison avec des étoffes brodées : le texte-tissu devient l'image de la toga picta du vainqueur. Composés dans les années 320-326, les Carmina d'Optatien accompagnent la marche de Constantin vers un pouvoir unique, dynastique et chrétien. La confrontation avec les monnaies révèle l'attention de l'auteur à l'actualité de la propagande impériale. Son éloge témoigne ainsi de la christianisation du pouvoir, à un moment où celui-ci garde des affinités avec la théologie solaire. Optatien développe particulièrement le thème de la lumière, qu'il met au service de l'idée dynastique en célébrant la gloria constantinienne. La poésie d'Optatien s'apparente à l'esthétique du bas-empire par son goût pour l'abstraction, le signe, et le stéréotype. Les vœux lies au renouvellement du charisme impérial confèrent une fonction liturgique aux carmina, susceptibles d'être associés aux grandes fêtes impérialesOptatianus Porfyrius transcended the Alexandrian figurated poem (technopaegnia). His square-like poems display internal pictures drawn by clever versus intexti : geometrical patterns, dedications, emblems. This poetry combines influences from epigraphy (characters placement, acrostiches), ornamental arts (mosaic patterns) and mathematics (combinatorics of reading paths and word permutations). To describe his art the poet uses the vocabulary of weaving. His works illustrate graphically this idea of the text as an intertwining. The weaving metaphor reminds of the embroidery: the text/fabric becomes the equivalent of the toga picta of the conqueror. Composed in the period 320-326, Optatianus' Carmina follow emperor Constantine steps toward a monarchic, dynastic and Christian rule. A parallel study of contemporary coins shows how Optatianus carefully exploits the evolution of the imperial propaganda. His praise give evidence of the Christianization of the executive power, precisely when it keeps connections with the cult of sol. Optatianus also emphasizes the theme of the light, with the purpose to celebrate the constantinian gloria. Optatianus poetry bears traits of the esthetics of the roman 4th century a. D. : a taste for abstraction, symbols and clichés. The vows associated to the renewal of the emperor's charisma give to the Carmina a liturgic value in harmony with the spirit of the main imperial celebrations
41
Li, Shi. "Hyper-heuristic cooperation based approach for bus driver scheduling." Phd thesis, Université de Technologie de Belfort-Montbeliard, 2013. http://tel.archives-ouvertes.fr/tel-00976554.
Full textAbstract:
The design of public transport system must take into account different dimensions to solve two main problems of optimization: the vehicles scheduling and driver scheduling. In our work, we focused on bus driver scheduling. Its objective is to minimize the number of drivers in accordance with social and environmental constraints. By its combinatorial nature, bus driver scheduling is considered a complex task in the design process of network transport. We have proposed an approach based on hyper-heuristics whose main advantage lies in their ability to adapt to different problems. We are particularly interested in a cooperative approach, which is able to take into account changes in the resolution process. We have extended the functionality and improved performance of the traditional framework of hyper- heuristics by proposing a pattern based on an organizational model. The proposed algorithm consists of a combination of several phases and several levels. The metaphor of the coalition is used to make cooperate several hyper-heuristics. The coalition is intended to favor diversified solutions and expand search capacity with decentralized control where each hyper-heuristic has certain autonomy. It is thus possible to consider different ways of cooperation between the hyper-heuristics: sharing solutions, learning by mimetism or carrying out different competitive search strategies. The experiment was carried out both on real-world instances and benchmarks. It gave good results on both quality of solution and execution time
42
Morlet, Sébastien. "L'apologétique chrétienne à l'époque de Constantin : la démonstration évangélique d'Eusèbe de Césarée." Paris 4, 2006. http://www.theses.fr/2006PA040220.
Full textAbstract:
La Démonstration évangélique est la seconde partie d’un grand diptyque apologétique composé par Eusèbe de Césarée (v. 265 – 339/340). Bien que ce diptyque constitue l’apologie chrétienne la plus longue de l’Antiquité, il n’a jamais fait l’objet d’une étude détaillée. La Démonstration évangélique est à la fois un écrit de polémique contre le judaïsme, un prolongement de la polémique antipaïenne ouverte dans la première partie de l’apologie (la Préparation évangélique) et surtout le point culminant d’une œuvre organique qu’Eusèbe conçoit comme un enseignement. Cette étude précise la place de la Démonstration évangélique dans les traditions antijuive et antipaïenne de l’Antiquité à travers une analyse approfondie de son contexte polémique et de son argumentation. Eusèbe innove par son projet de composer une apologie savante. À cette fin, il adapte à la polémique les méthodes et les commentaires de son maître spirituel Origène. La Démonstration évangélique est donc une œuvre originale située à mi-chemin entre la polémique et la recherche, dont l’influence est perceptible chez plusieurs polémistes postérieursThe Demonstratio evangelica is the second part of a large twofold apologia written by Eusebius of Caesarea (c. 265 – 339/340). Though this apologia is the longest one in all Antiquity, it has never been investigated in detail. The Demonstratio evangelica is at the same time an antijewish tract, a continuation of the antipagan controversy dealt with in the first part of the apologia (the Praeparatio evangelica), and above all the climax of an organic work which Eusebius conceived as a teaching process. This study emphasizes the place of the Demonstratio evangelica within the antijewish and antipagan traditions, by a throrough analysis of its polemical background and argumentation. Eusebius’ scholarly project is new within the apologetic tradition. The bishop of Caesarea applies to the controversy methods and commentaries he owes to his spiritual master Origen. In that respect, the Demonstratio evangelica is an original work, situated half-way between controversy and research, which influenced several later polemists
43
Mezin, Florent. "Des troupes alpines aux troupes de montagne : (1962-2012) : histoire d'un processus de légitimation professionnelleet d'affirmation d’une identité militaro-territoriale." Thesis, Université Grenoble Alpes (ComUE), 2016. http://www.theses.fr/2016GREAH035.
Full textAbstract:
Depuis leur création en 1888, les Alpins constituent une subdivision d’arme à part au sein de l’armée de terre française. Territorialement très marquées, ces unités ont pour mission originelle et spécifique de défendre la frontière alpine. En 1962, après deux guerres mondiales et deux guerres de décolonisation, la France entre dans une nouvelle ère. Face à l’évolution de la menace, le pays opte pour la nucléarisation de son armée. Dans ce contexte de guerre froide, les troupes alpines ne sont plus que des « troupes du territoire ». Elles se marginalisent et peinent à trouver leur place aussi bien dans le nouveau dispositif de sécurité et de défense nationale qu’au sein des territoires alpins en pleine mutation. Pourtant, en 1983, à la surprise générale, la 27e Division Alpine s’intègre dans la Force d’Action Rapide et participe à sa première opération extérieure. Cette OPEX au Liban marque le début d’une renaissance pour les Alpins. Le déploiement des soldats de montagne en Yougoslavie au cours des années 1990 puis en Afghanistan au cours des années 2000 assoit la légitimité opérationnelle des Alpins. Au XXIe siècle, l’armée des Alpes désormais professionnelle, occupe une nouvelle place dans les territoires de montagne et joue un rôle nouveau auprès des sociétés alpines. En effet, le combat de légitimation, de reconnaissance et de rayonnement de la « spécificité montagne » des troupes alpines ne se gagne pas seulement sur les champs de batailles. La quête de traditions nouvelles pour refonder une identité militaire et montagnarde, l’organisation de diverses cérémonies dans l’espace public, la construction d’un patrimoine commun sont autant d’armes aux mains du commandement de la 27e Brigade d’Infanterie de Montagne pour continuer d’exister malgré la « réforme perpétuelle » de la Défense française. La 27e Brigade d'Infanterie de Montagne reste aujourd’hui dépositaire des traditions des Alpins d’autrefois. La 27e BIM reste la brigade d’urgence de montagne de l’armée de Terre. De par ses capacités opérationnelles reconnues, la « 27 » met en œuvre des savoir-faire spécifiques sur les théâtres les plus divers, à l’intérieur ou à l’extérieur du territoire nationalSince their creation in 1888, the Alpins form a separate subdivision within the French Army. The primary and specific mission of these territorially very marked units is to defend the Alpine border. In 1962, after two world wars and two decolonization wars, France enters a new era. In response to the threat, the nuclearization of the army is decided by the country. In this context of cold war, the Alpines units are merely territory troops. They become marginalized and hardly find a place as well in the new safety and national defence features as within the Alpins territories which are undergoing profoundchange. However, in 1983, to widespread surprise, the 27e Division Alpine joins the Force d’Action Rapide and takes part in its first external operation. This OPEX (EXternal OPeration) in Lebanon marks a beginning of rebirth for the Alpins. Their operational legitimacy was established by the deployment of mountain soldiers in Yugoslavia in the 1990s and then in Afghanistan in the 2000s. In the XXIth century, the henceforth professional army of the Alps occupies a novel place in the mountain territories and plays a new role to the Alpin societies. Indeed, the struggle for legitimation, appreciation and influence of the “mountain specificity” of the Alpin troops is not to be won on the battlefields only. The search for new traditions in an attempt to rebuild a mountain military identity,the organisation of various ceremonies in the public space, the reconstruction of a common heritage are all weapons in the hands of the 27e Brigade d’Infanterie de Montagne command for the purpose of continuing to exist in spite of the “perpetual reform” of the “Défense française”. The 27e Brigade d'Infanterie de Montagne remains guardian of the traditions of the former Alpins. The 27e BIM stays the emergency brigade of the French land army. Due to its acknowledged operational capabilities, it implements its specific expertise in various theatres, within the national territory or outside
44
Teixeira, Manuel Ferreira Salavisa. "Infecção nosocomial por Clostridium difficile : caracterização da estirpe epidémica 027." Master's thesis, 2014. http://hdl.handle.net/10451/24359.
Full textAbstract:
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2014The incidence and severity of Clostridium difficile infection increased exponentially during the last decade, and is currently the third most prevalent nosocomial infection in the Western world. This phenomenon is directly correlated with the spread of an epidemic strain, classified as ribotype 027, characterized by the increased production of toxins A and B, production of another toxin (binary toxin) and high-level resistance to fluoroquinolones. Using a combination of strategies in the management of nosocomial Clostridium difficile infection that is focused not only on the application of barrier methods for preventing horizontal spread (hand washing, isolation, environmental hygiene), but also in reducing the consumption of " target- antibiotics " associated with a higher risk of Clostridium difficile infection was shown to be effective in reducing the incidence and severity of nosocomial C. difficile outbreaks. Currently one of the most significant limitations of therapeutic management of Clostridium difficile infection is the high rate of recurrence after treatment. In this respect , the emergence of new pharmacological agents such as fidaxomicin or research in the immune therapy with anti - toxin A and B vaccines and antibodies , has shown significant results reported by several clinical trials and could play in the future , a role first-line approach in the Clostridium difficile infection. This work reviews current literature regarding the particular characteristics associated with the epidemic strain 027, the prevention and control of nosocomial outbreaks of Clostridium difficile infection, current treatment options and new pharmacological approaches currently under investigation.
A incidência e gravidade da infecção por Clostridium difficile aumentaram exponencialmente no decorrer da última década, sendo actualmente a terceira infecção nosocomial mais prevalente no mundo ocidental. Este fenómeno correlaciona-se directamente com a disseminação de uma estirpe epidémica, classificada como ribótipo 027, caracterizada por uma produção aumentada de toxinas A e B, produção de uma terceira toxina (toxina binária) e elevada resistência a fluoroquinolonas. A utilização de uma combinação de estratégias na abordagem do surto nosocomial de infecção por Clostridium difficile que assente não só na aplicação de métodos barreira para prevenção da disseminação horizontal (lavagem das mãos, isolamento, higiene ambiental), mas também na redução do consumo de “antibióticos-alvo” associados a maior risco de colonização por C. difficile, mostrou ser efectivo na redução da incidência e gravidade da infecção por Clostridium difficile nosocomial. Actualmente uma das limitações mais significativas do manejo terapêutico da infecção por Clostridium difficile é a elevada taxa de recorrência pós-tratamento. Neste domínio, a emergência de novos agentes farmacológicos como a fidaxomicina ou a investigação no âmbito da terapia imunológica com anticorpos anti-toxina A e B e vacinas, tem revelado resultados significativos reportados por diversos ensaios clínicos, podendo vir a desempenhar no futuro, um papel de primeira linha na abordagem da infecção por Clostridium difficile. Este trabalho tem por objectivo a revisão literária das características particulares associadas à estirpe epidémica 027, medidas de prevenção e controlo de surtos nosocomiais de infecção por Clostridium difficile, opções terapêuticas actuais e novas abordagens farmacológicas em estudo.
45
Hill, Warren G. (Warren Gary) 1962. "Sulphation of glycosaminoglycans in cystic fibrosis / by Warren Gary Hill." 1995. http://hdl.handle.net/2440/18637.
Full textAbstract:
Erratum inserted on front fly leaf.Bibliography: p. 283-315.
xiv, 315 p., [3] leaves of plates : ill. (one col.) ; 30 cm.
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
To establish whether altered sulphation in cystic fibrosis could be demonstrated in different experimental systems, by focusing on glycosaminoglycans. The second aim was to establish the molecular basis for such a phenomenon.
Thesis (Ph.D.)--University of Adelaide, Dept. of Paediatrics, 1995
46
Montoya, Delilah. "Corazon Sagrado = Sacred Heart /." 1993. http://rmoa.unm.edu/docviewer.php?docId=nmupict2001-027.xml.
Full textAbstract:
Thesis (M.F.A.)--University of New Mexico, 1993.University of New Mexico, Dept. of Art and Art History, M.F.A. thesis project. Book (21 p. ; 23 cm.) is housed within the inside cover of portfolio and is held in place with a leather belt. Includes bibliographical references.
47
Paesler, Ferdinand. "Regionalentwicklung und Mensch-Umwelt-Interaktion - Zwei Fallbeispiele aus Kenia und der Demokratischen Republik Kongo." Doctoral thesis, 2015. https://doi.org/10.25972/WUP-978-3-95826-027-6.
Full textAbstract:
Der vielschichtige Begriff Entwicklung stellt die Basis für die multidisziplinäre Entwicklungsforschung, aber auch die Entwicklungspolitik und Entwicklungszusammenarbeit dar und wird demzufolge auf verschiedenste Art und Weise verwendet. Insbesondere zu den Auswirkungen regionaler Entwicklungsprozesse auf lokaler Ebene existieren innerhalb der entwicklungstheoretischen Ideengeschichte eine Vielzahl unterschiedlicher Zugänge, über die die vorliegende Arbeit einen kurzen Überblick gibt. Unter Berücksichtigung anthropogeographischer Ansätze zur Erforschung des Verhältnisses von Entwicklung und Raum werden im ersten (theoretischen) Teil die Konzepte der lokalen Partizipation sowie der Politischen Ökologie als geeignete Analyseinstrumente für das Verständnis konkreter lokaler Entwicklungsprozesse erarbeitet; Entwicklung wird hierbei akteurs- und kontextorientiert als Ergebnis von Mensch-Umwelt-Interaktionen angesehen. Im Rahmen eines case study research wird im zweiten Teil der Arbeit die Praxistauglichkeit dieser Analyseinstrumente überprüft. Hierfür werden in zwei Untersuchungsregionen regionale Entwicklungsdynamiken beschrieben und analysiert, um deren räumliche und soziale Auswirkungen zu verstehen. In beiden Gebieten (Mampu/Mbankana in der Demokratischen Republik Kongo sowie Wasini Island in Kenia) hat in den vergangenen Jahren eine durch unterschiedliche Prozesse verursachte rasante Regionalentwicklung stattgefunden, die die Gebiete jeweils deutlich von ihrem Umland abhebt. Im Fallbeispiel Wasini Island wurde die Entwicklung durch den (internationalen) Tourismus bedingt, in Mampu/Mbankana durch ein Entwicklungsprojekt der Hanns-Seidel-Stiftung (HSS). Für beide Gebiete wird zuerst der naturräumliche, politische und historische Kontext aufgezeigt, welcher die Rahmenbedingungen für die Analyse der einzelnen Akteure und Akteursgruppen darstellt. Sowohl für Wasini Island als auch für Mampu/Mbankana können während des Untersuchungszeitraums Ereignisse identifiziert werden, die von der einheimischen Bevölkerung (bzw. Teilen dieser) als stark situationsverändernd und zudem nicht endogen verursacht wahrgenommen werden (externe Krisen): in Wasini der drastische Einbruch der Touristenzahlen nach den Unruhen im Nachgang der Präsidentschaftswahlen (2007/08 Kenyan Crisis), im kongolesischen Untersuchungsgebiet der schrittweise Rückzug der HSS aus dem operativen Projekt ab 2009 und die damit einhergehende Übertragung von Verantwortung auf lokale Gremien und Organisationen. Durch die Zusammenführung der Ergebnisse aus beiden Fallbeispielen wird konstatiert, dass Entwicklung auf regionaler Ebene als ein kontext- und akteursabhängiger dynamischer Prozess anzusehen ist, der aus den kumulierten, in beide Richtungen wirksamen Mensch-Umwelt-Interaktionen in der betrachteten Region resultiert, und damit in der Tradition geopossibilistischer Perspektiven steht, in denen die natürliche bzw. geographische ebenso wie die gesellschaftliche Umwelt die Rahmenbedingungen für menschliches Handeln und damit Entwicklung vorgibt, jedoch nicht determiniertDevelopment as the fundamental concept of Development Studies, Politics and Cooperation is an inhomogeneously used term with a variety of different connotations. This dissertation gives in its theoretical part a short introduction to the history of development thought, focused especially on geographical approaches concerning regional development as well as the relationship between development and space. Thus, local participation and political ecology are identified as suitable instruments for analysing dynamics and actual processes of local development. So the stakeholder- and context-oriented approach leads to development as a result of human-environment interactions. To confirm the usability of the theoretical implications mentioned above, the second part contains a case study research to describe and analyse the regional development and its spatial and social effects in two field study areas. The actual developments in both regions ¬- Wasini Island in Kenya and Mampu/Mbankana in the Democratic Republic of the Congo - are thereby heavily affected by external influences, namely international tourism and nature conservation (Wasini), respectively a development cooperation project carried out by the Hanns Seidel Foundation (Mampu/Mbankana). The analyses also take into account the particular natural-spatial, political and historical context, being the framework for local stakeholders‘ actions. In both study areas events changing the situation can be found, which by large parts of local populations are experienced as exogenous crises: a dramatic decline of tourist arrivals due to the post-electoral riots (2007/08 Kenyan Crisis) in Wasini and the phasing out of Hanns Seidel Foundation‘s financial support in Mampu/Mbankana since 2009, including intraregional shifts of responsibilities and influence. As a result of both the theoretical and empirical findings, development on a regional level is analysed as a stakeholder- and context-dependent process which consists of the accumulated two-way human-environment interactions within a region. This perspective is founded on the tradition of geographical possibilism, because it shows the natural, geographical and social environments framing, but not determining, human actions and thus development processes
48
Wei, Wei. "Data mining using neural networks for large credit card record sites." Thesis, 2001. http://library1.njit.edu/etd/fromwebvoyage.cfm?id=njit-etd2001-027.
Full text
49
Petrov, Plamen V. "Applications of agent architectures to decision support in distributed simulation and training systems." Thesis, 2000. http://library1.njit.edu/etd/fromwebvoyage.cfm?id=njit-etd2000-027.
Full text
50
An, Yoo Jung. "Ontology learning for the semantic deep web." Thesis, 2008. http://library1.njit.edu/etd/fromwebvoyage.cfm?id=njit-etd2008-027.
Full text