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Journal articles on the topic '6220f'

Author: Grafiati

Published: 25 May 2024

Last updated: 31 July 2025

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1

Hobday, Timothy J., Rui Qin, Diane Lauren Reidy, et al. "Multicenter phase II trial of temsirolimus (TEM) and bevacizumab (BEV) in pancreatic neuroendocrine tumor (PNET)." Journal of Clinical Oncology 30, no. 4_suppl (2012): 260. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.260.

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260 Background: Recent placebo-controlled phase III trials of the mTOR inhibitor everolimus and the VEGF/ PDGF receptor inhibitor sunitinib in PNET noted improved progression-free survival (PFS). However, objective response rates (RR) with these agents are <10%. Preclinical studies suggest enhanced anti-tumor effects with combined mTOR and VEGF targeted therapy. Methods: We conducted a phase II trial of the mTOR inhibitor TEM (25 mg IV q week) and the VEGF-A monoclonal antibody BEV (10 mg/kg IV q 2 weeks) in patients (pts) with well or moderately differentiated PNET and progressive disease

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2

Cohen, Deirdre Jill, Paul J. Christos, Joseph A. Sparano, et al. "A randomized phase II study of vismodegib (V), a hedgehog (HH) pathway inhibitor, combined with FOLFOX in patients (pts) with advanced gastric and gastroesophageal junction (GEJ) carcinoma: A New York Cancer Consortium led study." Journal of Clinical Oncology 31, no. 4_suppl (2013): 67. http://dx.doi.org/10.1200/jco.2013.31.4_suppl.67.

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67 Background: The HH pathway is overexpressed in gastroesophageal (GE) tumors. Pre-clinically, HH inhibitors have demonstrated a reduction in GE tumor growth, cell motility and invasiveness. V, an oral small-molecule antagonist of the Hh pathway, has previously been safely combined with FOLFOX chemotherapy. Methods: Pts with untreated, metastatic or locally advanced gastric or GEJ adenocarcinoma were randomized 1:1, stratified by institution and disease status (with or w/o distant mets) to FOLFOX (ox 85 mg/m2, LV 200 mg/m2, 5-FU bolus 400 mg/m2, 5-FU infusion 2400 mg/ m2 over 48 hrs) q14d plu

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3

Cohen, Deirdre Jill, Paul J. Christos, Hedy Lee Kindler, et al. "Vismodegib (V), a hedgehog (HH) pathway inhibitor, combined with FOLFOX for first-line therapy of patients (pts) with advanced gastric and gastroesophageal junction (GEJ) carcinoma: A New York Cancer Consortium led phase II randomized study." Journal of Clinical Oncology 31, no. 15_suppl (2013): 4011. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.4011.

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4011 Background: The HH pathway is overexpressed in gastroesophageal (GE) tumors. Pre-clinically, HH inhibitors have demonstrated a reduction in GE tumor growth, cell motility and invasiveness. V, an oral small-molecule antagonist of the Hh pathway, has previously been safely combined with FOLFOX chemotherapy. Methods: Pts with untreated metastatic or locally advanced gastric or GEJ adenocarcinoma were randomized 1:1, stratified by institution and disease status (with or w/o distant mets) to FOLFOX (ox 85 mg/m2, LV 200 mg/m2, 5-FU bolus 400 mg/m2, 5-FU infusion 2400 mg/ m2 over 48 hrs) q14d pl

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4

Morgan, Robert, Amit M. Oza, Rui Qin, et al. "A multicenter phase II study of bevacizumab (B) and temsirolimus (T) in women with recurrent epithelial ovarian cancer (OC): A study of the Mayo, Chicago, California, New York, Southeast, and Princess Margaret Phase II Consortia." Journal of Clinical Oncology 31, no. 15_suppl (2013): 5517. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5517.

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5517 Background: Anti-angiogenic therapy is active in OC; the combination of VEGF and mTOR inhibitors is hypothesized to further improve activity. This report is the OC cohort of a multi-histology phase II study assessing the activity and toxicity of B/T. Methods: Patients (Pts) with recurrent epithelial OC who had received ≤ 2 chemotherapy regimens and no prior treatment with a VEGF or mTOR inhibitor were eligible. A two-stage design was used with second stage accrual if >6 pts had objective responses (OR) or >10 pts of the first 25 remained progression-free (PF) at six months (mo). Pre

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5

Ramalingam, S. S., M. Maitland, P. Frankel, et al. "Randomized, double-blind, placebo-controlled phase II study of carboplatin and paclitaxel with or without vorinostat, a histone deacetylase inhibitor (HDAC), for first-line therapy of advanced non-small cell lung cancer (NCI 7863)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 8004. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.8004.

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8004 Background: Vorinostat, a HDAC inhibitor, enhances paclitaxel and platinum-mediated anti-cancer activity in preclinical studies by enhanced tubulin acetylation and DNA fragmentation respectively. Promising activity with carboplatin (C), paclitaxel (P), and vorinostat in patients with advanced NSCLC in the phase I study (Ramalingam et al, Clin Cancer Res, 2007) prompted this placebo-controlled, randomized phase II study. Methods: Pts. with stage IIIB (wet) or IV NSCLC, performance status (PS) 0/1, no prior therapy and adequate bone marrow, renal and hepatic function were randomized (2:1) f

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6

Nedashkovskaya, Olga I., Seung Bum Kim, Dong Sung Shin, Irina A. Beleneva, and Valery V. Mikhailov. "Fulvivirga kasyanovii gen. nov., sp. nov., a novel member of the phylum Bacteroidetes isolated from seawater in a mussel farm." International Journal of Systematic and Evolutionary Microbiology 57, no. 5 (2007): 1046–49. http://dx.doi.org/10.1099/ijs.0.64641-0.

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A novel, strictly aerobic, heterotrophic, gliding, Gram-negative, oxidase-, catalase-, β-galactosidase- and alkaline phosphatase-positive marine bacterium, designated strain KMM 6220T, was isolated from seawater and studied by using a polyphasic taxonomic approach. The DNA G+C content of strain KMM 6220T was 59.9 mol%. The predominant fatty acids were iso-C15 : 1, iso-C15 : 0, iso-C15 : 0 3-OH, iso-C17 : 0 3-OH and C16 : 1 ω7/iso-C15 : 0 2-OH. Phylogenetic analysis based on 16S rRNA gene sequencing revealed that strain KMM 6220T formed a cluster with the misclassified strains [Flexibacter] agg

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7

PODHORN??, J., and KR??IAKM. "FANANSERIN (RR 62203), A POSSIBLE NOVEL ATYPICAL ANTIPSYCHOTIC?" Behavioural Pharmacology 7, Supplement 1 (1996): 89. http://dx.doi.org/10.1097/00008877-199605001-00202.

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8

Doble, A., O. Ferris, E. Heuillet, J. Ménager, and J. C. Blanchard. "3H-RP 62203: IN VITRO 5-HT2 BINDING STUDIES." Clinical Neuropharmacology 15 (1992): 581B. http://dx.doi.org/10.1097/00002826-199202001-01132.

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9

Malgouris, Christiane, Fabienne Flamand, and Adam Doble. "Autoradiographic studies of RP 62203, a potent 5-HT2 receptor antagonist. Pharmacological characterization of [3H]RP 62203 binding in the rat brain." European Journal of Pharmacology 233, no. 1 (1993): 37–45. http://dx.doi.org/10.1016/0014-2999(93)90346-j.

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10

Pinheiro, Gilson de Assis, Sérgio Henrique de Souza Alves, Pedro Paulo Murce, and Antonio Pedro de Mello Cruz. "Envolvimento dos receptores 5-HT2 da amígdala nos níveis de ansiedade induzidos pela exposição de ratos ao labirinto em cruz elevado." Psicologia: Teoria e Pesquisa 18, no. 3 (2002): 329–35. http://dx.doi.org/10.1590/s0102-37722002000300013.

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O efeito de microinjeções intra-amigdalóides do antagonista 5-HT2A/2C de receptores serotoninérgicos RP 62203 (1,0; 2,5; 5,0 mg) foi investigado em medidas tradicionais e etológicas (esquadrinhar, espreitar e explorações da extremidade) de ansiedade de ratos no labirinto em cruz elevado. A dose de 5,0 mg aumentou as porcentagens de entrada e de tempo nos braços abertos, sem alterar no número de entradas nos braços fechados. As categorias esquadrinhar, espreitar e explorações da extremidade também foram alteradas pela droga. As doses de 2,5 e 5,0 mg aumentaram o tempo gasto em esquadrinhar e di

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11

Tang, Liang, Yunliang Jiang, and Jungang Lou. "Reliability Architecture for Collaborative Robot Control Systems in Complex Environments." International Journal of Advanced Robotic Systems 13, no. 1 (2016): 17. http://dx.doi.org/10.5772/62201.

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12

El-Batal, Ahmed Ibrahim, Fatma Abd El-Lateef Gharib, Safia Mohammed Ghazi, Amal Zakaria Hegazi, and Asmaa Gamal Mohamed Abd El Hafz. "Physiological Responses of Two Varieties of Common Bean (Phaseolus VulgarisL.) to Foliar Application of Silver Nanoparticles." Nanomaterials and Nanotechnology 6 (January 2016): 13. http://dx.doi.org/10.5772/62202.

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13

Zhu, Qiuguo, Yichao Mao, Rong Xiong, and Jun Wu. "Adaptive Torque and Position Control for a Legged Robot Based on a Series Elastic Actuator." International Journal of Advanced Robotic Systems 13, no. 1 (2016): 26. http://dx.doi.org/10.5772/62204.

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14

Stutzmann, J. M., B. Eon, M. Roux, M. Lucas, J. C. Blanchard, and P. M. Laduron. "RP 62203, a 5HT2 antagonist, enhances slow wave sleep in rats." European Journal of Pharmacology 183, no. 4 (1990): 1394. http://dx.doi.org/10.1016/0014-2999(90)94522-y.

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15

Kaspi, Victoria M., R. N. Manchester, Simon Johnston, A. G. Lyne, and N. D'Amico. "PSR J1341-6220 - A young pulsar in a supernova remnant." Astrophysical Journal 399 (November 1992): L155. http://dx.doi.org/10.1086/186630.

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16

Stutzmann, Jean-Marie, Bertrand Eon, Michelle Lucas, Jean-Charles Blanchard, and PierreM Laduron. "RP 62203, A 5-Hydroxytryptamine2 Antagonist, Enhances Deep NREM Sleep in Rats." Sleep 15, no. 2 (1992): 119–24. http://dx.doi.org/10.1093/sleep/15.2.119.

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17

Frolova, Olena. "CAUSING HARM TO PHARMACEUTICAL ACTIVITY AS AN OBJECT OF CRIMINAL LAW PROTECTION." Scientific Journal of Polonia University 62, no. 1 (2024): 151–57. http://dx.doi.org/10.23856/6220.

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The article is devoted to the issue of causing harm to pharmaceutical activity as an object of criminal law protection. As the author notes, the current legislation regulating the procedure for pharmaceutical activity contains certain guidelines for determining harm to the specified social values or its individual fragments. In the opinion of the author, characterizing the formation of harm "within" pharmaceutical activity as an object of criminal law protection and its consideration in the composition of criminal offenses, it is necessary to determine the types of actions that affect pharmace

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18

Doble, A., D. Girdlestone, O. Piot, et al. "Pharmacological characterization of RP 62203, a novel 5-hydroxytryptamine 5-HT2 receptor antagonist." British Journal of Pharmacology 105, no. 1 (1992): 27–36. http://dx.doi.org/10.1111/j.1476-5381.1992.tb14206.x.

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19

Koch, Claudia, Stefan Hertwig, and Bernd Appel. "Nucleotide Sequence of the Integration Site of the Temperate Bacteriophage 6220, Which Carries the Shiga Toxin Gene stx1ox3." Journal of Bacteriology 185, no. 21 (2003): 6463–66. http://dx.doi.org/10.1128/jb.185.21.6463-6466.2003.

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ABSTRACT The integration site, attR, of the Shiga toxin-encoding phage 6220 (stx 1ox3) has been determined. The phage integrates into the chromosome of its Escherichia coli host strain, CB6220, within a gene that is homologous to gene Z2577 and encodes an oxidoreductase. This new integration site was found in different Stx1ox3-producing enterohemorrhagic E. coli strains, which were analyzed by PCR.

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20

Wang, Na, R. N. Manchester, R. Pace, et al. "Glitches in Southern Pulsars." International Astronomical Union Colloquium 177 (2000): 109–10. http://dx.doi.org/10.1017/s0252921100059194.

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AbstractParkes timing observations of 31 mostly young pulsars over nearly nine years are described. A total of 29 glitches were detected, of which 19 are previously unreported. Twelve glitches were seen in PSR J1341–6220, making this the most frequently glitching pulsar known, and the largest known glitch was detected in PSR J1614–5047. Distributions of glitch parameters were investigated.

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21

Dhasmana, Swati, Anupam Dhasmana, Stella Rios, et al. "Abstract 6220: TRIP13 augments pancreatic cancer progression- An integrated systems biology study." Cancer Research 84, no. 6_Supplement (2024): 6220. http://dx.doi.org/10.1158/1538-7445.am2024-6220.

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Abstract Background- Pancreatic cancer (PanCa) is one of the most aggressive forms of cancer and its incidence rate is continuously increasing every year. It is expected that by 2030, PanCa will become the 2nd leading cause of cancer related deaths in the United States due to the lack of understanding of the complexity of disease, early diagnostic methods, and extremely poor survival. Despite great advancements in biomedical research, there are very limited modalities available for the early detection of PanCa and its treatment. Thus, understanding of disease biology and identification of newe

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22

Kirby, Zamyat. "Dir: Farouk Ubaysi . Prod: Nazir Khaja and Bashir Matin for Islamic Information Services, PO Box 6220. Altadena, CA 91003-6220. Tel: 800-531-4447. Fax: 818-791-9824." Middle East Studies Association Bulletin 31, no. 2 (1997): 198–99. http://dx.doi.org/10.1017/s0026318400035951.

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23

Heuillet, Edith, François Petitet, Serge Mignani, et al. "The naphtosultam derivative RP 62203 (fananserin) has high affinity for the dopamine D4 receptor." European Journal of Pharmacology 314, no. 1-2 (1996): 229–33. http://dx.doi.org/10.1016/s0014-2999(96)00554-7.

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24

Lever, John R., and Suzanne M. Johnson. "Synthesis of a radioiodinated analogue of the serotonin 5-HT2A receptor ligand RP 62203." Journal of Labelled Compounds and Radiopharmaceuticals 41, no. 2 (1998): 143–50. http://dx.doi.org/10.1002/(sici)1099-1344(199802)41:2<143::aid-jlcr63>3.0.co;2-p.

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25

PEDRIALI, LUCA, MAURIZIO SOSSO, and BRUNO DELL’ANGELO. "Naticid gastropods from the middle Miocene of western Ukraine." Zootaxa 4700, no. 2 (2019): 151–95. http://dx.doi.org/10.11646/zootaxa.4700.2.1.

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The paper covers 11 species of naticid gastropods occurring in the lower Serravallian (Upper Badenian) strata of western Ukraine (Central Paratethys). The studied material (over 1,700 naticids) represents six genera and 11 species, of which eight are new: Cochlis odovychenorum, Cochlis ukrainensis, Tectonatica anistratenkorum, Tectonatica pseudoprietoi, Euspira sirenkoi, Payraudeautia ermesi, Payraudeautia sabrinae and Payraudeautia varovtsiana. Additionally, we have also identified Euspira protracta (Eichwald, 1830), Polinices staszici (Friedberg, 1923) and Sinum affinis (Eichwald, 1830). A l

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26

Wolfe, Rachel M., Al‐Walid Mohsen, Cate Walsh Vockley, et al. "Novel GUCY2C variant causing familial diarrhea in a Mennonite kindred and a potential therapeutic approach." American Journal of Medical Genetics Part A 185, no. 7 (2021): 2046–55. http://dx.doi.org/10.1002/ajmg.a.62207.

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27

Robin, Nathaniel H. "Choose your words carefully." American Journal of Medical Genetics Part A 185, no. 7 (2021): 1953. http://dx.doi.org/10.1002/ajmg.a.62206.

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28

Roebke, Logan J., Josh W. Vander Maten, and Ghattas Alkhoury. "Hyperbaric oxygen management of recurrent cellulitis in poikiloderma with neutropenia." American Journal of Medical Genetics Part A 185, no. 7 (2021): 2150–52. http://dx.doi.org/10.1002/ajmg.a.62204.

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29

Wang, Raymond Yu‐Jeang. "To John M. Graham Jr, who called me into a career in clinical genetics." American Journal of Medical Genetics Part A 185, no. 9 (2021): 2646–48. http://dx.doi.org/10.1002/ajmg.a.62200.

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30

De Luca, Chiara, Simonetta Picone, Matteo Cassina, et al. "Craniosynostosis is a feature of CHD7 ‐related CHARGE syndrome." American Journal of Medical Genetics Part A 185, no. 7 (2021): 2160–63. http://dx.doi.org/10.1002/ajmg.a.62208.

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31

Rosenfeld, Jill A., Rui Xiao, Mir Reza Bekheirnia, et al. "Heterozygous variants in SPTBN1 cause intellectual disability and autism." American Journal of Medical Genetics Part A 185, no. 7 (2021): 2037–45. http://dx.doi.org/10.1002/ajmg.a.62201.

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32

Coulie, Richard, Dmitriy M. Niyazov, Michael J. Gambello, Elodie Fastré, Pascal Brouillard, and Miikka Vikkula. "Hypotrichosis‐lymphedema‐telangiectasia syndrome: Report of ileal atresia associated with a SOX18 de novo pathogenic variant and review of the phenotypic spectrum." American Journal of Medical Genetics Part A 185, no. 7 (2021): 2153–59. http://dx.doi.org/10.1002/ajmg.a.62205.

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33

Ülgen Tekerek, Nazan, Başak Nur Akyıldız, and Muammer Hakan Poyrazoğlu. "Comparison Between Dead Space/Tidal Volume and Work of Breathing in Predicting Extubation Failure in Critically Ill Children." Turkish Journal of Pediatric Emergency and Intensive Care Medicine 5, no. 1 (2018): 1–5. http://dx.doi.org/10.4274/cayd.62207.

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34

Szubert, Sebastian, Artur Łojewski, Rafał Moszyński, Arkadiusz Lisowski, Stefan Sajdak, and Dariusz Szpurek. "Ultrasonographic features and CA125 levels of hormonally active ovarian tumors." Polish Gynaecology 87, no. 04 (2016): 254–59. http://dx.doi.org/10.17772/gp/62201.

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35

Kulik-Rechberger, Beata, Artur Kościesza, Elżbieta Szponar, and Justyna Domosud. "Hepcidin and iron status in pregnant women and full-term newborns in first days of life." Polish Gynaecology 87, no. 04 (2016): 288–92. http://dx.doi.org/10.17772/gp/62202.

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36

Kurzawińska, Grażyna, Magdalena Barlik, Krzysztof Drews, et al. "Coexistence of ACE (I/D) and PAI-1(4G/5G) gene variants in recurrent miscarriage in Polish population." Polish Gynaecology 87, no. 04 (2016): 271–76. http://dx.doi.org/10.17772/gp/62203.

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37

Trenkić, Milan, Jasmina Popović, Vesna Kopitović, Artur Bjelica, Radomir Živadinović, and Sonja Pop-Trajković. "Flexible GnRH antagonist protocol vs. long GnRH agonist protocol in patients with polycystic ovary syndrome treated for IVF: comparison of clinical outcome and embryo quality." Polish Gynaecology 87, no. 04 (2016): 265–70. http://dx.doi.org/10.17772/gp/62205.

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38

Zawiejska, Agnieszka, Ewa Wender-Ożegowska, and Jacek Brązert. "Chronic and gestational metabolic disorders have a different impact on late-pregnancy endothelial function in pregnant women." Polish Gynaecology 87, no. 04 (2016): 283–87. http://dx.doi.org/10.17772/gp/62209.

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39

Coloma, J. F., L. R. Valverde, and M. García. "Estimación de los costes de construcción de viviendas rústicas mediante Redes Neuronales Artificiales." Informes de la Construcción 71, no. 554 (2019): 293. http://dx.doi.org/10.3989/ic.62206.

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La Administración Pública y el promotor privado buscan tener un conocimiento previo de los costes de cualquier edificación. Existen en la literatura numerosas metodologías que permiten realizar la valoración de un inmueble, pero siempre se ha realizado para viviendas urbanas en ciudades grandes o medianas. Esta investigación propone el uso de Inteligencia Artificial para el estudio de viviendas rústicas en pequeñas ciudades como la de Cáceres (España). La investigación propone un procedimiento de Redes Neuronales Artificiales (RNA) para conseguir por un lado estimar a través de un método autom

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40

Sanchez‐Lara, Pedro A., Katheryn Grand, Maria K. Haanpää, et al. "Thinking outside “The Box”: Case‐based didactics for medical education and the instructional legacy of Dr John M. Graham, Jr." American Journal of Medical Genetics Part A 185, no. 9 (2021): 2636–45. http://dx.doi.org/10.1002/ajmg.a.62202.

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41

Di Fede, Elisabetta, Angela Peron, Elisa Adele Colombo, Cristina Gervasini, and Aglaia Vignoli. "SLC35F1 as a candidate gene for neurodevelopmental disorders resembling Rett syndrome." American Journal of Medical Genetics Part A 185, no. 7 (2021): 2238–40. http://dx.doi.org/10.1002/ajmg.a.62203.

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42

Ergen, Hüseyin, and Ferdi ÇOKKESER. "ÖZEL OKUL ÖĞRETMENLERİNİN YAŞADIĞI SORUNLAR." Uluslararası İnovatif Eğitim Araştırmacısı CİLT 2 SAYI 1, CİLT 2 SAYI 1 (2022): 111–36. http://dx.doi.org/10.29228/iedres.62209.

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43

Özdemir, Fulya, and Ayten AKATAY. "Zamansal Motivasyon Teorisi Ve Erteleme Davranışı." Social Sciences Studies Journal 98, no. 98 (2022): 1664–73. http://dx.doi.org/10.29228/sssj.62201.

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44

SUCU, Hakan, and Recep BOZYİĞİT. "Akıllı Botanik Park Uygulamasının Ortaöğretim Öğrenci Görüşlerine Göre Değerlendirilmesi." Social Sciences Studies Journal 98, no. 98 (2022): 1654–63. http://dx.doi.org/10.29228/sssj.62200.

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45

Kesgin, Makbule Tokur. "EDİTÖRDEN: Etki Büyüklüğü Gerekli mi?" Yaşam Boyu Hemşirelik Dergisi 1, no. 1 (2022): i—v. http://dx.doi.org/10.29228/llnursing.62208.

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46

Husser, Daniela, Vincent Pellissier, Sven Hohenstein, et al. "Hospital care of patients with inherited cardiomyopathies in Germany during the Covid‐19 pandemic insights from the German‐wide Helios hospital network." American Journal of Medical Genetics Part A 185, no. 7 (2021): 2278–82. http://dx.doi.org/10.1002/ajmg.a.62209.

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47

Çaltık Yılmaz, Aysun, and Sevgi Başkan. "İlköğretim ve Lise Öğrencilerinin AIDS’e İlişkin Bilgilerinin Değerlendirilmesi." Güncel Pediatri 12, no. 1 (2014): 9–15. http://dx.doi.org/10.4274/jcp.62207.

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48

Çonkar, Seçil, Recep Sancak, and Canan Aygün. "The Role of Neonatal Sepsis in the Development of Allergic Diseases in Childhood." Journal of Pediatric Research 3, no. 4 (2016): 175–79. http://dx.doi.org/10.4274/jpr.62207.

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49

Babayiğit, Münire, Zehra Baykal Tutal, Necla Dereli, Handan Güleç, Mustafa Alparslan Babayiğit, and Eyüp Horasanlı. "Are We Being Informed Correctly During the Patient Transfer to the Intensive Care Units?" Türk Yoğun Bakım Derneği Dergisi 14, no. 2 (2016): 54–58. http://dx.doi.org/10.4274/tybdd.62207.

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50

MOHAMMADI NEJAD, Solmaz, Hilal ÖZGÜNEŞ, and Nursen BAŞARAN. "Pharmacological and Toxicological Properties of Eugenol." Turkish Journal of Pharmaceutical Sciences 14, no. 2 (2017): 201–6. http://dx.doi.org/10.4274/tjps.62207.

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