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1
Gruner, J., J. vom Scheidt, and R. Wunderlich. "On the analytic representation of the correlation function of linear random vibration systems." Universitätsbibliothek Chemnitz, 1998. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-199801272.
Abstract:
This paper is devoted to the computation of statistical characteristics of
the response of discrete vibration systems with a random external excitation.
The excitation can act at multiple points and is modeled by a time-shifted
random process and its derivatives up to the second order. Statistical characteristics
of the response are given by expansions as to the correlation length
of a weakly correlated random process which is used in the excitation model.
As the main result analytic expressions of some integrals involved in the expansion terms are derived.
2
Walklate, Jonathan. "Kinetic characterisation of disease causing mutations in the embryonic and ß-cardiac myosin motor domain." Thesis, University of Kent, 2016. https://kar.kent.ac.uk/60910/.
Abstract:
Myosin myopathies are a growing area of research not only to understand the nature of the disease and how it can occur, but also to gain insight into how the myosin molecule works. Point mutations are a great way of examining how regions of myosin interact, however, given that there are over 800 amino acids in the motor domain alone, pinpointing key residues can be challenging. The missense mutations in the myosin molecule that lead to disease are ideal then to investigate residue changes that will have an effect on the function of the motor. The expression of recombinant skeletal myosin class II molecules has only recently become possible. Previous studies into the function of the embryonic myosin isoform have shown it to be a slow type myosin similar to the β-cardiac isoform. Here stopped-flow kinetic analysis of recombinant embryonic myosin S1 showed it has a tight ADP affinity and slow ADP release, characteristic of the β-cardiac myosin. Analysis of the three most common mutations in the embryonic myosin that cause Freeman-Sheldon syndrome (R672H, R672C, and T178I) showed a significantly reduced ATP hydrolysis, and ATPase Vmax and KM. Modelling of the cycle found that the mutations will be detached from actin for longer due to reduced ATP hydrolysis rate and a slower estimated phosphate release step. Another more common myopathy is hypertrophic cardiomyopathy (HCM) which can be cause by mutations in a multitude of sarcomeric proteins, most notably the β-cardiac myosin. HCM is usually found in adolescents and young adults; however cases are beginning to emerge involving young children. Stopped-flow kinetic analysis of one of these mutations, H251N, shows more significant effects on the myosin function than 'adult' HCM mutations, including; a weaker ADP affinity, tighter ATP affinity, and slower detachment from actin rate constant. However the difference in severity is not apparently clear from the stopped-flow data alone. These results highlight new key areas on the myosin molecule that are essential for its correct function. The myosin motor is an intricate machine with multiple parts that need further investigation to truly understand its function and the impact of disease causing mutations.
3
Mason, Amanda. "Integrating a focus on form into task-based language teaching : an investigation of four communicative tasks conducted by advanced learners of English using synchronous text-based computer-mediated communications." Thesis, Liverpool John Moores University, 2010. http://researchonline.ljmu.ac.uk/6010/.
4
Corte, Coi Claudio. "Metodologie per l'analisi statistica di dati di sequencing relativi a un esperimento di rna interference." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amslaurea.unibo.it/6010/.
Abstract:
La RNA interference è un processo attraverso il quale alcuni piccoli frammenti di RNA (19-25 nucleotidi) sono in grado di silenziare l'espressione genica. La sua scoperta, nel 1998, ha rivoluzionato le concezioni della biologia molecolare, minando le basi del cosiddetto Dogma Centrale. Si è visto che la RNAi riveste ruoli fondamentali in meccanismi di regolazione genica, nello spegnimento dell'espressione e funziona come meccanismo di difesa innata contro varie tipologie di virus. Proprio a causa di queste implicazioni richiama interesse non solo dal punto di vista scientifico, ma anche da quello medico, in quanto potrebbe essere impiegata per lo sviluppo di nuove cure.
Nonostante la scoperta di tale azione desti la curiosità e l'interesse di molti, i vari processi coinvolti, soprattutto a livello molecolare, non sono ancora chiari.
In questo lavoro si propongono i metodi di analisi di dati di un esperimento prodotto dall'Istituto di Biologia molecolare e cellulare di Strasburgo. Nell'esperimento in questione vengono studiate le funzioni che l'enzima Dicer-2 ha nel pathway - cioè la catena di reazioni biomolecolari - della RNA interference durante un'infezione virale nel moscerino della frutta Drosophila Melanogaster.
Per comprendere in che modo Dicer-2 intervenga nel silenziamento bisogna capire in quali casi e quali parti di RNA vengono silenziate, a seconda del diverso tipo di mutazione dell'enzima stesso.
Dunque è necessario sequenziare l'RNA nelle diverse condizioni sperimentali, ottenendo così i dati da analizzare.
Parte dei metodi statistici che verranno proposti risultano poco convenzionali, come conseguenza della peculiarità e della difficoltà dei quesiti che l'esperimento mette in luce.
Siccome le tematiche affrontate richiedono un approccio sempre più interdisciplinare, è aumentata considerevolmente la richiesta di esperti di altri settori scientifici come matematici, informatici, fisici, statistici e ingegneri. Questa collaborazione, grazie a una diversità di approccio ai problemi, può fornire nuovi strumenti di comprensione in ambiti che, fino a poco tempo fa, rientravano unicamente nella sfera di competenza dei biologi.
5
Stefanelli, Silvia <1983>. "Il potere normativo delle Corti sul processo." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/6010/.
Abstract:
La tesi intende offrire una riflessione in merito al potere degli organi giurisdizionali di disporre normativamente su determinati aspetti del processo che si svolge dinanzi ad essi, sostituendosi così al legislatore.
Il piano di indagine della tesi si sviluppa prevalentemente nella descrizione della realtà europea davanti alle autorità giurisdizionali di Lussemburgo, attraverso continui riferimenti a pronunce giurisprudenziali.
La candidata si sofferma, preliminarmente, definendo, in termini generali, l’origine e l’applicazione dei c.d. atti di soft law in ambito europeo e soffermandosi sul ruolo che ricopre la giurisprudenza nell’ordinamento europeo.
Sempre nel capitolo di apertura, un accenno è dedicato al panorama italiano che, alla luce delle recenti e continue riforme processuali ed, in particolare, della lettura costituzionalmente orientata del processo civile in forza della sua ragionevole durata, sta conoscendo, sempre più largamente, il fenomeno dei c.d. protocolli.
La tesi si sviluppa, poi, in altri tre capitoli, nei quali sono analizzati tre esempi di manifestazione del potere normativo degli organi giurisdizionali europei sul processo.
La candidata passa, così, all’esame delle “Istruzioni pratiche alle parti”, sviscerando le disposizioni ivi contenute alla luce di casi giurisprudenziali, al fine di poter definire la reale efficacia di tali atti e la loro vincolatività nei confronti dei rappresentanti delle parti.
A tale capitolo segue quello sull’applicazione del rinvio pregiudiziale tra soft law (c.d. Raccomandazioni) e giurisprudenza.
Infine, la candidata svolge le ultime riflessioni sul potere “eccezionale” della Corte di giustizia di limitare nel tempo gli effetti delle proprie sentenze interpretative. Potere che, in questo caso, si manifesta non mediante l’emanazione di atti di soft law, ma attraverso le proprie pronunce giurisprudenziali.The thesis aims to reflect on the power of the courts to provide normatively on some aspects of the proceedings that take place before them, thus replacing the legislator. The investigation plan of the thesis is developed considering the European situation before the courts of Luxembourg, through continuous references to cases law. The candidate focuses, firstly, defining, in general terms, origin and application of so-called soft law acts in Europe and focusing on the role of jurisprudence in the European system. In the first chapter, a hint is dedicated to the Italian overview, in the light of recent reforms of civil proceedings and with particular reference to the phenomenon of so-called “protocols”. The thesis is then developed in three other chapters, in which the candidate analyzes three examples of the manifestation of normative power of the European Courts on the proceedings. The candidate examines the "Practice Directions to parties": identifying the provisions contained in the light of cases law, in order to define the real effectiveness of these acts and their binding against parties’ representatives. The third chapter is about preliminary ruling procedure between soft law (so-called “Recommendation to national courts and tribunals in relation to the initiation of preliminary ruling proceedings) and jurisprudence. In the end, the candidate plays the latest reflections on "exceptional" power of the Court of Justice of the European Union to limit the temporal effects of its interpretative judgments. Power which, in this case, is manifested not through the enactment of soft law acts, but through its case law.
6
Tran, Grant. "Modeling drug efficacy in the tumour microenvironment with Saccharomyces cerevisiae genome-wide screens in hypoxic conditions." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/60210.
Abstract:
Hypoxia, the state of reduced oxygen, is a microenvironment found in many solid tumours and is correlated with an increased risk in patient mortality. This is due to an increase in resistance to radiotherapy and chemotherapy as well as a decrease in drug efficacy. The mechanisms and cellular factors (gene products) associated with this reduced chemotherapeutic efficacy in hypoxia remains unclear. This research looks to identify cellular processes and pathways that cancerous cells are able to exploit in order to survive and thrive in this microenvironment. The eukaryotic model baker’s yeast Saccharomyces cerevisiae combined with a genome-wide approach was used to screen the yeast knockout collection for specific genotypes that are sensitive to the hypoxic environment alone, and in combination with commonly used chemotherapeutics. Pathways and processes identified in these screens include transcriptional regulation, cytoskeleton maintenance, ribosomal biogenesis, macromolecular complex assembly and the heat shock response. The combination of heat and hypoxia was found to result in a synergistic effect that drastically affected cell fitness. DNA-damaging chemotherapeutics screened in hypoxic conditions showed reduced efficacy. Genotypes most sensitive to drugs in the hypoxic environment fall into Gene Ontology (GO) terms categorized in the response to the specific mechanism of the drug. This includes DNA repair processes such as homologous repair, post-replicative repair and mismatch repair. The mechanistic specificity uncovered in these screens suggests that the hypoxic environment exacerbates drug-specific stresses, and the identified genotypes highlight gene products and pathways critical for these responses. Cell survival and success in this microenvironment therefore requires adaptations to these exacerbated stresses, a phenomenon successfully accomplished by resistant tumour cells. This research contributes to our understanding of cellular biology under this cancer microenvironment, and provides data to highlight the challenges in using chemotherapeutics to treat tumours.Pharmaceutical Sciences, Faculty of
Graduate
7
Tafteh, Reza. "Three-dimensional super-resolution imaging: from cellular surface to interior." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/60910.
8
Wang, Da S. M. Massachusetts Institute of Technology. "Distinguishing codes from noise : fundamental limits and applications to sparse communication." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/60710.
Abstract:
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (p. 99-100).
This thesis investigates the problem of distinguishing codes from noise. We develop a slotted channel model where in each time slot, the channel input is either a codeword or a noise sequence. In this model, successful communication requires both correctly detecting the presence of a codeword and decoding it to the correct message. While the decoding problem has been extensively studied, the problem of distinguishing codes from noise is relatively new, and we ask the following question regarding the "distinguishability" of a channel code: given a noisy channel and a code with a certain rate, what are the fundamental limits of distinguishing this code from noise at the output of the channel? The problem of distinguishing codes from noise involves both detection and decoding. In our analysis, we first extend the classical channel coding problem to incorporate the requirement of detection, which admits both miss and false alarm errors. Then we investigate the fundamental limits of code distinguishing in terms of the error exponents of miss and false alarm error probabilities. In a scenario that miss probability is required to vanish asymptotically but not necessarily exponentially, we characterize the maximum false alarm error exponent at each rate, and show that an i.i.d. codebook with typicality decoding is sufficient to achieve the maximum exponent. In another scenario that requires certain miss error exponent, we show that for DMC channels, the i.i.d. codebook is suboptimal and the constant composition codebook achieves the best known performance. For AWGN channels, we develop a clustered spherical codebook that achieves the best known performance in all operating regimes. This code distinguishability problem is strongly motivated by the synchronization problem in sparse communication, a new communication paradigm where transmissions take place intermittently and each transmission consists of a small amount of data. Our results show that, in sparse communication, the traditional approach of conducting synchronization and coding separately is suboptimal, and our approach of designing codes for joint synchronization and information transmission achieves better performance, especially at high rates. Therefore, for systems with sparse transmissions such as sensor networks, it is beneficial to adopt the joint sync-coding architecture instead of the traditional separate sync-coding architecture.
by Da Wang.
S.M.
9
Nshimyimana, Jean Pierre. "Evaluating human fecal contamination sources in Kranji Reservoir Catchment, Singapore." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/60810.
Abstract:
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2010.Cataloged from PDF version of thesis.
Includes bibliographical references (p. 120-132).
Singapore government through its Public Utilities Board is interested in opening Kranji Reservoir to recreational use. However, water courses within the Kranji Reservoir catchment contain human fecal indicator bacteria above recreational water quality criteria; their sources and distribution under dry and wet weather are also unknown. The goal of this study was to evaluate the distribution of E. coli under dry and wet weather, to determine the sources of the human fecal contamination, and to validate the use of human-specific 16S rRNA Bacteroides marker for human fecal source tracking in Singapore and tropical regions. Environmental water and DNA water samples (332) collected in the Kranji catchment in January and July 2009, and January 2010 were analyzed for E. coli using Hach m-ColiBlue24@ and IDEXX Colilert Quanti-Tray*/2000. Touchdown PCR and Nested-PCR HF183F assays were used to assess the absence or presence of the HF marker in Kranji catchment. Selected positive HF marker samples were sequenced and mapped using a phylogenetic tree to confirm their similarity in base order to the human factor identified in the temperate climate. The indicator bacteria (E. coli) results showed consistently high E. coli concentrations (geometric mean 3240 CFU/100 ml) in dry and wet weather in residential, horticultural and animal farming areas. The DNA analysis results showed that 94% of the 34 environmental DNA water samples collected in residential, horticultural and animal farming areas were positive to the HF marker. Generally, 74% and 94% of DNA samples respectively collected in dry and wet weather in the Kranji catchment were positive. The sequence and phylogenetic tree analysis confirmed that the HF marker identified was similar to the HF marker identified in temperate climates. Based on the results we conclude that human fecal contamination sources are widespread in the animal farming, horticultural and residential areas of Kranji catchment. The HF marker analysis validated its applicability as 16S rRNA gene of human-specific Bacteroides for human fecal source tracking in Singapore and elsewhere in tropical climates.
by Jean Pierre Nshimyimana.
S.M.
10
Wong, Katherine Wing-Shan. "Design of a small-scale continuous linear motion pharmaceutical filtration module." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/60210.
Abstract:
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2010.Cataloged from PDF version of thesis.
Includes bibliographical references (p. 50).
A new small-scale continuous linear motion pharmaceutical filtration prototype was designed, fabricated, and tested. The goal of this unit is to filter an Active Pharmaceutical Ingredient (API) from a mixture of API molecules, ethyl acetate, and possible contaminants. This unit is important in the development of a small-scale continuous pharmaceutical manufacturing process by Novartis, which would lower costs and increase product flexibility and production. A compliant blade is mounted onto a linear guide assembly and driven by a stepper motor to filter the API mixture through a porous metal filter. The mixture enters into the middle of the filtration unit; the excess ethyl acetate and dissolved contaminants are pulled through the filter by a vacuum pump, leaving the desired API molecules on the filter surface. The API is then moved across the filter by the blade to output collectors at either end. The unit itself takes up 0.03 cubic meters, an eighth of the size of the current equivalent production model. This unit has been tested to successfully filter the API from the rest of the mixture and will help determine if a rotary or linear style filtration system should be used as the final design.
by Katherine Wing-Shan Wong.
S.B.
11
Winck, Cesar Augustus. "Impactos do pagamento pela qualidade na cadeia produtiva do leite na região oeste de Santa Catarina." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/60510.
Abstract:
A região Oeste de Santa Catarina é responsável por 72,4% do leite produzido no Estado e 5,8% do leite brasileiro e esta produção está baseada na agricultura familiar, predominando as cooperativas de produção agropecuária. A qualidade do leite é um dos fatores que mais preocupam toda a cadeia agronegocial do leite no país e os programas de pagamento por qualidade surgem como uma iniciativa para estimular todos os componentes da cadeia a investirem na melhoria da produção leiteira. Neste contexto, estão inseridas as Cooperativa “A” e “B” que possuíam entre as suas diversas atividades de produção e comércio, a área de coleta de leite entre seus sócios. A Cooperativa “B” não possuía programa de pagamento pela qualidade do leite e Cooperativa “A” implantou seu Programa de Pagamento pela Qualidade do Leite – PPQL em 2008. O objetivo do estudo foi analisar os impactos socioeconômicos e técnicos do sistema de pagamento por qualidade sobre a Cadeia Produtiva da região Oeste catarinense. Por meio de revisão de literatura, análise documental, aplicação de questionários com produtores e entrevistas com dirigentes, sob a luz da Teoria da Tomada de Decisão, identificou-se que o PPQL foi implantado na Cooperativa “A” para estimular os produtores a aumentarem o volume de produção e a cumprirem as exigências das Instruções Normativas 51 (2002) e 62 (2011). Após o início do PPQ, o número de produtores de leite estabilizou, houve um aumento na produtividade das propriedades (33,1%), no recolhimento de leite pela cooperativa (25,3%), na qualidade do leite entregue (redução de CCS e CBT), além da melhora dos preços pagos por litro aos produtores. A atividade leite é a principal atividade das propriedades (71,4%) na região, com uma produção média de 202,2 litros/dia e 14,5 litros/vaca em uma área média de 18,9 ha. Os produtores estão satisfeitos com a atividade leiteira (60,7%), conhecem o funcionamento do programa de pagamento pela qualidade (96,4%), reinvestem os valores recebidos do leite para a melhoria produtiva e consideram que o PPQL não os fideliza, pois entregariam leite à cooperativa, mesmo que este não estivesse implantado. Conclui-se que o PPQL impactou positivamente em diversos aspectos sociais, econômicos e técnicos na Cadeia Produtiva, melhorando a qualidade do leite coletado e incentivando a cooperativa e os produtores a investirem na produção.The West region of the Santa Catarina State is responsible for 72.4% of the milk produced in the state and 5.8% of the Brazilian milk and this production is based in family farming, prevailing cooperatives of agricultural production. The quality of the milk is one of the factors that most concerns the whole agribusiness chain of milk in the country and the payment programs for quality emerged as an initiative to encourage the whole chain to invest in improvements in the milk production. Are inserted in this context the Cooperatives “A” and “B” which had among their diverse activities of production and trade, the area of collecting milk among its members. The Cooperative “B” did not have a program of payment for the quality of the milk and the Cooperative “A” implanted its Program of Payment for the Quality of the Milk – PPQL in 2008. The aim of this study was to analyze the socioeconomic and technical impacts of the system of payment for quality over the Productive Chain of the West region of the Santa Catarina State. Through literature review, documentary analysis, questionnaire with producers and interviews with directors, and in the light of the Theory of Decision Making, it was identified that the PPQL was implemented in Cooperative “A” to encourage the producers to increase productions volume and meet the requirements of Instruction 62 (NI 62). After the beginning of the PPQL, the number of milk producers stabilized, there was an increase in the productivity in the farms (33.1%), in the collection of milk by the cooperative (25.3%), in the quality of the milk delivered (reduction of SCC and TBC), besides an improvement in the prices paid per liter to the producers. The milk activity is the main activity in the properties (71.4%) in this area, with an average production of 202.2 liters/day and 14.5 liters/cow in an average area of 18.9 ha. The producers are satisfied with the milk activity (60.7%), they know how the program to pay for quality works (96.4%), reinvest the amounts received of the milk to improve production and consider that the PPQL does not create loyalty because they would deliver milk to the Cooperatives even if the program had not been implemented. It was concluded that the PPQL positively impacted in many social, economical and technical aspects of the Productive Chain, improving the quality of the milk collected and encouraging the cooperative and the producers to invest in the production.
12
Frade, Edison Vlademir De Almeida. "Os direitos da vítima da criminalidade." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/60710.
Abstract:
No plano internacional têm sido reconhecidos direitos à vítimas da criminalidade, o que lhes possibilita a assunção de uma nova posição na resolução do conflito penal. Seja no âmbito das Nações Unidas, onde se destaca a Resolução n. 40/34 de 1985, da ONU, que trouxe consigo a Declaração de Princípios Básicos de Justiça relativos às Vítimas da Criminalidade e Abuso de Poder, seja no âmbito europeu, onde se destacam as iniciativas do Conselho da Europa e mais recentemente as iniciativas da União Européia, as vítimas da criminalidade têm visto redesenhadas sua posição, seus direitos e visto reconhecida sua condição de pessoa humana dotada de dignidade. A dissertação apresenta um primeiro capítulo contendo uma breve teoria geral sobre os principais aspectos relativos às vítimas e uma sintética evolução histórica de sua posição no conflito penal, em um segundo capítulo uma análise dos principais documentos relativos às vítimas de crimes no âmbito europeu e em um terceiro capítulo uma análise do principal documento no âmbito da ONU relativos às vítimas de crimes, Resolução n. 40/34 de 1985, da ONU e a Declaração de Princípios Básicos de Justiça relativos às Vítimas da Criminalidade e Abuso de PoderInternationally recognized rights have been victims of crime, enabling them to assume a new position in the penal settlement of the conflict. Whether at the United Nations, which highlights the Resolution No. 40/34 1985, the UN, which has brought the Declaration of Basic Principles of Justice for Victims of Crime and Abuse of Power is in the European context, where we highlight the initiatives of the Council of Europe and more recently of the Union's Union, crime victims have since redesigned their position, their rights and their status as recognized as human beings endowed with dignity. It is a draw in the first chapter a brief general theory about the main aspects related to the victims and a synthetic historical evolution of its position in the criminal conflict in a second chapter a review of key documents relating to victims of crimes within the European framework and in a third chapter an analysis of the main document at the UN on victims of crime, Resolution No. 40/34 1985, and the UN Declaration of Basic Principles of Justice for Victims of Crime and Abuse of Power.
13
Gwebu, Nomonde Nomfundo. "Estimating the value and economic contribution of agricultural production in the former homelands of South Africa." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/60810.
Abstract:
The value and economic contribution of agricultural production in the former homelands of South Africa has become increasingly important to measure because it is critical to our understanding of the role agriculture plays in household food security in these regions and the contribution by this section of the agricultural sector to the economy. Yet, two decades into the Democratic South Africa we still fail to consistently provide accurate estimates of this sectors value.
The fundamental premise of this dissertation is to estimate the value and economic contribution of agricultural production in the former homelands of South Africa so that the subsistence agricultural sector can be well understood in terms of its characteristics and its value. The main focus of this study is therefore placed on black subsistence farmers in the former homelands of South Africa, mostly because these areas are under great pressure to maintain food self-sufficiency.
The main hypothesis of this study is that, the value and economic contribution of agricultural production in the former homelands is significant when compared with the contribution by the commercial agricultural sector in South African. In order to test this hypothesis, three different data sets were analysed because none of these data sets individually provide exhaustive information for the purposes of this study. These data sets include primary data, such as the Agricultural Research Council (ARC) sample survey data from the OR Tambo District municipality conducted in 2015. The secondary data used in this study include the ARC sample survey 2013, the Income and Expenditure Survey (IES) 2010/2011 conducted by Statistics South Africa (Stats SA), and the National Income Dynamics Study (NIDS) waves 1 to 3 conducted by the Southern African Labour Development Research Unit (SALDRU).
The Gross Margin (GM) analysis approach was used in this study to estimate the economic contribution of agricultural production. In interrogating the NIDS waves and IES 2010/2011 data sets, two types of variables which can be used to estimate the economic contribution of agricultural production are provided. The first type of variables are the self-reported values of agricultural goods consumed from home production, which are found in both the NIDS and IES datasets. The second type of variables are quantities of agricultural goods harvested and the value of sales from home production, found in the NIDS datasets.
The variables to estimate the economic contribution of agricultural production would appear to be the self-reported values of agricultural goods consumed from home production. Using the NIDS data the estimated value of consumption from home production in current prices was R207 million based on wave 1 data, R80,5 million based on wave 2 data, and R529 million based on wave 3 data. Using the IES data the estimated value of production for home consumption in current prices was R359 million in 2010/2011. In investigating the 2010/2011 figures estimated in this study several issues arise with regard to the number of agriculturally active households and the value of agricultural goods consumed from home production. The most important issue, is that self-reported values of agricultural goods consumed by households introduce an added source of inequality to the measurement of output. According to the UNSD (2005), households can inaccurately assign values to self-produced goods because of a lack of information about local market prices. In order to avoid this source of inequality in the measurement of the agricultural sectors contribution, estimates of the economic contribution of agricultural production were pursued, based on local market prices.
It was determined that only the NIDS and the ARC data sets have variables to directly estimate the economic contribution of agricultural production based on the GM approach. The variables include: quantities of crop and livestock goods harvested and the value of sales from own production. Using the ARCs data it was estimated that the annual GM per household per year in 2012 prices was R1 985.32 based on the 2013 data and R8 892.85 based on the 2015 data. Using the NIDS waves 1 and 3 data, it was estimated that the annual GM per household was R1 017.85 based on wave 1 data and R3 535.42 based on wave 3 data in 2012 prices. The NIDS wave 2 data set does not provide farm input cost and livestock production variables. As a result, it was only possible to estimate the annual Gross Farm Income (GFI) per household which was R1 973 in 2010/2011 in 2012 prices. The latter results are somewhat consistent with the ARC 2013 and 2015 figures, although not directly comparable. The Agricultural Research Council-Department of Rural Development and Land Reform (ARC-DRDLR) project introduced in the OR Tambo District municipality has played a key role in terms of changing the mind-set of farmers. Therefore, programmes such as the ARC-DRDLR project should be introduced with more vigour. Such programmes should, however, not undermine subsistence households consumption type activates.Dissertation (MSc (Agric))--University of Pretoria, 2017.
Agricultural Economics, Extension and Rural Development
MSc (Agric)
Unrestricted
14
Van, Wyk Bianca Idalina. "State-owned entities and the impact on competition law." Diss., University of Pretoria, 2016. http://hdl.handle.net/2263/60110.
Abstract:
The South African Competition Act 89 of 1998, as amended addresses an array of principles
and issues surrounding competition policy. However, it has become apparent that the Act
remains silent regarding state-aid and moreover state owned entities in relation to competition
law. This paper analyses the development of competition policy within South Africa and the
origins of state-owned entities and state aid. The aim of this paper is to evaluate whether
state-owned entities encourage, strengthen or diminish the concept and purpose of
competition. Furthermore, a comparative analysis will be done between South Africa and
current and previous Member States of the European Union in an attempt to decipher whether
state-owned entities are efficiently regulated and utilised to promote the objectives set out in
the Competition Act. Lastly, this study will include possible recommendations which are on
par with global trends or models as to how state-owned entities and state aid should be
administered within the Republic.Mini Dissertation (LLM)--University of Pretoria, 2016.
Mercantile Law
LLM
Unrestricted
15
Tayob, Ilhaam. "Seeking spatial justice : empowering the everyday through an architecture that integrates the spatial and social realms." Diss., University of Pretoria, 2016. http://hdl.handle.net/2263/60210.
Abstract:
This dissertation explores Johannesburg's inner-city precinct of Joubert Park. It
intends to bridge the gap between the everyday community of the park and the
extraordinary heritage and memory of the site. Through a grassroots
investigation of 1he existing community, the project looks to empower the
everyday person and create a platform for their development, specifically
focusing on economy and education in the city. The project makes use of the
theories of spatial justice as a tool to analyse and understand the community's
relationship with the space they occupy and the social environment in which
they exist.
Architecturally, the project seeks to use this socio-spatial understanding as a
guideline of how to create a spatially just and empowering environment in the
inner city. Additionally, looking to establish a model for the development of the
existing inner-city fabric that begins to foster a relationship between building,
street edge, andl pedestrian. Exploring not just the physical upliftment of the
fabric, but the well-being and of the existing community and their needs, goals
and aspirations.Die verhandeling ondersoek die Johannesburg se middestad buurt van Joubertpark. Dit beoog om die gaping tussen die alledaagse gemeenskap van die Park en die buitengewone erfenis en geheue van die omgewing te oorbrug.Deur 'n voetsoolvlak ondersoek van die bestaande gemeenskap, is die projek se doel die bematigi111g van die alledaagse persoon en behels 'n platform vir die ontwikkeling daarvan,daar is n spesifike fokus op die ekonomie en onderwys in die stad. Die projek maak gebruik van die teoriee van ruimtelike geregtigheid as 'n 1instrument om te ontleed en te verstaan wat die gemeenskap se verhouding is met die ruimte wat hulle bewoon en die sosiale omgewing waarin hulle bestaan. Argitektonies, beoog die projek om hierdie sosio-ruimtelike begrip te gebruik as 'n riglyn om 'n ruimtelik net en bemagtigende omgewing te skep in die middestad. Daar word oak beoog om 'n model te vestig vir die ontwikkeling van die bestaande middestad konsepte om 'n verhouding te bevorder tussen die geboue, straat rand, en voetgangers. Ondersoek van nie net die fisiese opheffing van die struktuur nie, maar die welsyn van die bestaande gemeenskap en hul behoeftes, doelwitte en aspirasies.
Mini Dissertation (MArch (Prof))--University of Pretoria, 2016.
Architecture
MArch (Prof)
Unrestricted
16
Payne, Megan Gayle. "The relationship between psychological wellbeing and health-related physical fitness in professional rugby players." Diss., University of Pretoria, 2016. http://hdl.handle.net/2263/60410.
Abstract:
Rugby Union is a popular sport both internationally and nationally. The sport has seen a rise in high-intensity activity and is more physically demanding on players since turning professional in 1995. Over the past decade, professional rugby players have made frequent appearances in the media due to lapses in psychological, physical, and social wellbeing, suggesting professional rugby players may experience compromised health. Research has largely ignored rugby players' health when health is defined beyond injury. The present study aimed to provide insight into the health of professional rugby players by investigating two components of health, namely psychological and physical wellbeing and the relationship between these facets. Two hundred and thirty-eight (238) professional male rugby union players, situated at the Investec Rugby Academy participated in the study. Psychological wellbeing (PW) was measured by the State Trait Personality Inventory (form Y) (STPI-Y) and the Sport Competitive Anxiety Test (adult form) (SCAT-A). Physical wellbeing was defined as health-related physical fitness (HRPF). HRPF was assessed by measurements of the rugby players' body composition, physical fitness, and heart health. Pearson's correlation co-efficient was calculated between the variables used to measure HRPF and PW. The results showed the rugby players experience average levels of competitive anxiety, above average levels of anger, anxiety, and depression and a relatively high level of curiosity. The rugby players had a high level of HRPF, with the exception of body composition (particularly BMI), cardiovascular endurance, muscle strength and endurance, and heart health (when measured according to the CSI), which indicate a moderate risk to the players' health. Furthermore, the results show significant correlations between variables of HRPF and PW in the rugby players. The findings that indicate professional rugby players do not experience optimal PW and HRPF, as well as the significant correlations found between the variables of the rugby players PW and HRPF, suggest these players may be in a state of overtraining or experiencing overtraining syndrome.Mini Dissertation (MA)--University of Pretoria, 2016.
Psychology
MA
Unrestricted
17
Morallane, Mary Harriet. "The relationship between personality traits and cognitive adaptability of established entrepreneurs." Thesis, University of Pretoria, 2016. http://hdl.handle.net/2263/60510.
Abstract:
Cognitive adaptability has been conceptualised as the ability to effectively and appropriately change decision policies (i.e. to learn) given feedback (inputs) from the environmental context in which cognitive processing is embedded. Based on a large sample of 2650 established entrepreneurs in South Africa, this study attempts to determine how entrepreneurs cognitively adapt to unpredictable entrepreneurial environments. Multidimensional constructs representing cognitive adaptability and the Big Five personality traits were operationalised and empirically investigated. It was hypothesised that the Big Five personality trait dimensions of openness to experience, conscientiousness, extraversion and agreeableness are positively related to the cognitive adaptability dimensions of goal orientation, metacognitive knowledge, metacognitive experience, and metacognitive choice and monitoring. Neuroticism was hypthesised to be negatively related to the cognitive adaptability dimensions of goal orientation, metacognitive knowledge, metacognitive experience, metacognitive choice and monitoring. Hypotheses were tested using structured equation modelling and correlational and regression analysis. Results provide support for subcomponents of the Big Five personality traits. Intellectual interest (openness to experience), goal striving (conscientiousness), activity (extraversion), prosocial orientation (agreeableness) were found to be positively related to cognitive adaptability. They were found to be negatively related to prior metacognitive knowledge. Self-reproach (neuroticism) was found to be negatively related to cognitive adaptability. It was found to be positively related to prior metacognitive knowledge.
This research builds on and extends existing literature on cognitive adaptability in an entrepreneurial context by bringing together two streams of literature from psychology metacognition and personality traits. The implications of the process for dynamic, adaptable thinking are important in an emerging context such as that found in South Africa. The results of this study will inform the practice of policy makers who are trying to encourage start-up entrepreneurs to think about thinking in unpredictable entrepreneurial environments. In terms of methodology, the use of a sample of established entrepreneurs is desirable for this type of research since metacognition is better studied in entrepreneurs who are involved in a series of activities.Thesis (PhD)--University of Pretoria, 2016.
Business Management
PhD
Unrestricted
18
Donzelli, G. "Dynamics of spoke patterns in the solutal convective instability of a nanofluid." Doctoral thesis, Università degli Studi di Milano, 2008. http://hdl.handle.net/2434/60010.
19
Böhm, Walter, and Kurt Hornik. "On Two-Periodic Random Walks with Boundaries." Department of Statistics and Mathematics, WU Vienna University of Economics and Business, 2008. http://epub.wu.ac.at/936/1/document.pdf.
Abstract:
Two-periodic random walks are models for the one-dimensional motion of particles in which the jump probabilities depend on the parity of the currently occupied state. Such processes have interesting applications, for instance in chemical physics where they arise as embedded random walk of a special queueing problem. In this paper we discuss in some detail first passage time problems of two-periodic walks, the distribution of their maximum and the transition functions when the motion of the particle is restricted by one or two absorbing boundaries. As particular applications we show how our results can be used to derive the distribution of the busy period of a chemical queue and give an analysis of a somewhat weird coin tossing game.Series: Research Report Series / Department of Statistics and Mathematics
20
Kandji, Baye Matar. "Stochastic recurrent equations : structure, statistical inference, and financial applications." Electronic Thesis or Diss., Institut polytechnique de Paris, 2023. http://www.theses.fr/2023IPPAG004.
Abstract:
Nous nous intéressons à l'étude des propriétés théoriques des équations récurrentes stochastiques (SRE) et de leurs applications en finance. Ces modèles sont couramment utilisés en économétrie, y compris en économétrie de la finance, pour styliser la dynamique d'une variété de processus tels que la volatilité des rendements financiers. Cependant, la structure de probabilité ainsi que les propriétés statistiques de ces modèles sont encore mal connues, particulièrement lorsque le modèle est considéré en dimension infinie ou lorsqu'il est généré par un processus non indépendant. Ces deux caractéristiques entraînent de formidables difficultés à l'étude théorique de ces modèles. Dans ces contextes, nous nous intéressons à l'existence de solutions stationnaires, ainsi qu'aux propriétés statistiques et probabilistes de ces solutions.Nous établissons de nouvelles propriétés sur la trajectoire de la solution stationnaire des SREs que nous exploitons dans l'étude des propriétés asymptotiques de l'estimateur du quasi-maximum de vraisemblance (QMLE) des modèles de volatilité conditionnelle de type GARCH. En particulier, nous avons étudié la stationnarité et l'inférence statistique des modèles GARCH(p,q) semi-forts dans lesquels le processus d'innovation n'est pas nécessairement indépendant. Nous établissons la consistance du QMLE des GARCH (p,q) semi-forts sans hypothèses d'existence de moment, couramment supposée pour ces modèles, sur la distribution stationnaire. De même, nous nous sommes intéressés aux modèles GARCH à deux facteurs (GARCH-MIDAS); un facteur de volatilité à long terme et un autre à court terme. Ces récents modèles introduits par Engle et al. (2013) ont la particularité d'avoir des solutions stationnaires avec des distributions à queue épaisse. Ces modèles sont maintenant fréquemment utilisés en économétrie, cependant, leurs propriétés statistiques n'ont pas reçu beaucoup d'attention jusqu'à présent. Nous montrons la consistance et la normalité asymptotique du QMLE des modèles GARCH-MIDAS et nous proposons différentes procédures de test pour évaluer la présence de volatilité à long terme dans ces modèles. Nous illustrons nos résultats avec des simulations et des applications sur des données financières réelles.Enfin, nous étendons le résultat de Kesten (1975) sur le taux de croissance des séquences additives aux processus superadditifs. Nous déduisons de ce résultat des généralisations de la propriété de contraction des matrices aléatoires aux produits d'opérateurs stochastiques. Nous utilisons ces résultats pour établir des conditions nécessaires et suffisantes d'existence de solutions stationnaires du modèle affine à coefficients positifs des SREs dans l'espace des fonctions continues. Cette classe de modèles regroupe la plupart des modèles de volatilité conditionnelle, y compris les GARCH fonctionnelsWe are interested in the theoretical properties of Stochastic Recurrent Equations (SRE) and their applications in finance. These models are widely used in econometrics, including financial econometrics, to explain the dynamics of various processes such as the volatility of financial returns. However, the probability structure and statistical properties of these models are still not well understood, especially when the model is considered in infinite dimensions or driven by non-independent processes. These two features lead to significant difficulties in the theoretical study of these models. In this context, we aim to explore the existence of stationary solutions and the statistical and probabilistic properties of these solutions.We establish new properties on the trajectory of the stationary solution of SREs, which we use to study the asymptotic properties of the quasi-maximum likelihood estimator (QMLE) of GARCH-type (generalized autoregressive conditional heteroskedasticity) conditional volatility models. In particular, we study the stationarity and statistical inference of semi-strong GARCH(p,q) models where the innovation process is not necessarily independent. We establish the consistency of the QMLE of semi-strong GARCHs without assuming the commonly used condition that the stationary distribution admits a small-order moment. In addition, we are interested in the two-factor volatility GARCH models (GARCH-MIDAS); a long-run, and a short-run volatility. These models were recently introduced by Engle et al. (2013) and have the particularity to admit stationary solutions with heavy-tailed distributions. These models are now widely used but their statistical properties have not received much attention. We show the consistency and asymptotic normality of the QMLE of the GARCH-MIDAS models and provide various test procedures to evaluate the presence of long-run volatility in these models. We also illustrate our results with simulations and applications to real financial data.Finally, we extend a result of Kesten (1975) on the growth rate of additive sequences to superadditive processes. From this result, we derive generalizations of the contraction property of random matrices to products of stochastic operators. We use these results to establish necessary and sufficient conditions for the existence of stationary solutions of the affine case with positive coefficients of SREs in the space of continuous functions. This class of models includes most conditional volatility models, including functional GARCHs
21
Martorell, Bofill Xavier. "Dynamic Scheduling of Parallel Applications on Shared-Memory Multiprocessors." Doctoral thesis, Universitat Politècnica de Catalunya, 1999. http://hdl.handle.net/10803/6010.
22
Mir, Hasan S. "Source localization using airborne sensor arrays in the presence of manifold perturbations /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/6010.
23
川畑, 博昭, and Hiroaki Kawabata. "ペルーにおける「大統領中心主義」の統治構造(ニ) : 大統領の再選問題を手がかりに." 名古屋大学大学院法学研究科, 2002. http://hdl.handle.net/2237/6010.
24
Higgins, Kelly Jean. "Regulation of vascular endothelial growth factor receptor-2 in pancreatic and breast cancer cells by Sp proteins." Texas A&M University, 2003. http://hdl.handle.net/1969.1/6010.
Abstract:
Vascular endothelial growth factor receptor-2 (VEGFR2) is a key
angiogenic factor, and angiogenesis is an important physiological process
associated with neovascularization, growth, and metastasis of many different
tumors. The mechanism of VEGFR2 gene expression was investigated in
MiaPaCa-2, Panc-1, and AsPC-1 pancreatic cancer cells transfected with a
series of VEGFR2 promoter deletion/mutated constructs, and the results
indicated that the GC-rich âÂÂ60 to âÂÂ37 region of the promoter was essential for
VEGFR2 expression in these cell lines. EMSA and ChIP assays showed that Sp
proteins are expressed and bind to the proximal GC-rich region of the VEGFR2
promoter. RNA interference studies on Sp proteins demonstrated that Sp1, Sp3,
and Sp4 all contributed to VEGFR2 gene/protein expression in pancreatic
cancer cells.
VEGFR2 gene expression was also investigated in ZR-75 and MCF-7
breast cancer cells. ZR-75 cells treated with 10 nM 17b-estradiol (E2) increased
VEGFR2 mRNA levels/protein expression. The VEGFR2 promoter was induced
by E2 in ZR-75 cells, and analysis of the VEGFR2 promoter identified the GC rich -60 to -37 region that was required for E2-mediated transactivation. EMSA
and ChIP assays confirmed that Sp1, Sp3, and Sp4 proteins are expressed in
ZR-75 cells and bind the proximal GC-rich region of the VEGFR2 promoter.
RNA interference was used to determine the relative contributions of Sp proteins
on hormonal regulation of VEGFR2 through ER/Sp complexes, and interestingly,
in ZR-75 cells, hormone-induced activation of VEGFR2 involves ERa/Sp3 and
ERa/Sp4 but not ERa/Sp1.
In MCF-7 cells treated with 10 nM E2, VEGFR2 mRNA levels were
decreased. Analysis of the VEGFR2 promoter revealed that the same GC-rich
region important for E2-mediated upregulation in ZR-75 cells was responsible for
E2-dependent downregulation of VEGFR2 gene expression in MCF-7 cells.
EMSA and ChIP assays confirmed that Sp1, Sp3, and Sp4 proteins are
expressed in MCF-7 cells and bind to the proximal GC-rich region of the
VEGFR2 promoter. RNA interference studies showed that Sp1, Sp3, and Sp4
are involved in the E2-mediated downregulation of VEGFR2 in MCF-7 cells, and
ERa/Sp protein-promoter interactions are accompanied by recruitment of the
corepressor SMRT using the ChIP assay.
25
Lang, David J. "Taxation and regulation under the Canadian Constitution." Thesis, University of Ottawa (Canada), 1990. http://hdl.handle.net/10393/6010.
26
Parks, Ashley Ann. "Dissolved Nutrient Distributions in the Gulf of Mexico Following the Deepwater Horizon Oil Spill." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/6010.
Abstract:
The Deepwater Horizon (DWH) oil spill in the Gulf of Mexico (GoM) in the spring of 2010 introduced 4.4 million of barrels of oil to the ecosystem. Some biodegradation of the oil occurs when microorganisms, particularly bacteria, metabolize the oil as a carbon source. During this process, the microbes also require nutrients for energy. An introduction of oil at this magnitude has the ability to induce large blooms of microbes, which in turn can affect nutrient concentrations. Microbial petroleum degradation decreases nutrient concentrations, whereas the microbial assimilation and decay of organic matter increase nutrient concentrations. This study assessed whether any changes in nitrate, ammonium, and/or phosphate concentrations from historical levels could be attributed to the oil spill as a result of biodegradation, and how those changes can impact the GoM ecosystem. Nutrient samples were collected at discrete depths throughout the water column, in a cross-shelf transect inland from the spill site outside the DeSoto Canyon, in August 2010, February 2011, and May 2011 (four months to one year after the spill). In August 2010, a subsurface oil plume was found at depths of 1000 m to 1200 m. At the same depth of ~1000 m, a significant decrease in nitrate was observed, indicating the biodegradation of oil by heterotrophic bacteria of the aphotic zone, compared to earlier data during August 2000, when no known oils were present. Overall temporal increases in ammonium and dissolved organic nitrogen (DON) were observed both in near-surface waters and at an intermediate depth of ~400 m next to the walls of the DeSoto Canyon, suggesting an incremental die-off of both plankton and benthic organisms during accelerated recycling of nutrients. Continued decreases of phosphate were observed into February 2011, supporting ongoing biodegradation then as well. By May 2011, however, there were more increases in near-surface ammonium concentrations, compared to April 2000, with the implication that continued interseasonal recycled nitrogen accumulations may have been due to a decadal ecological regime shift, after a combination of top-down overfishing, petroleum perturbations, and/or increases of toxic harmful algal blooms (HABs).
27
Criswell, Leah. "Neutron diffraction and quasielastic neutron scattering studies of films of N-alkanes and a branched alkane absorbed on graphite." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/6010.
Abstract:
Thesis (Ph. D.)--University of Missouri-Columbia, 2007.The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on March 11, 2008) Includes bibliographical references.
28
Topuz, Rasim. "Web-based database applications : an educational, administrative management system for military academies." Thesis, Monterey, California. Naval Postgraduate School, 2002. http://hdl.handle.net/10945/6010.
Abstract:
Approved for public release; distribution is unlimited.Not only does a military academy have all the information overload of a normal university but it also has the extra burden of the military environment. Without a reliable information system, administrative and educational functions cannot be performed. This thesis deals with the problem of administrative overload in managing student, faculty, regiment personnel and course data in a military academy. It proposes an Educational Administrative Management System (EAMS), a Web-based data management system, as a solution. With this goal in mind, existing client-server architectures, server side application development tools and database technologies are explored, and the best configuration of these tools is selected. Some of them are recommended. As a result of the study, Java Servlets and Java Server Pages are found as the optimal server-side programming tool for the application. A working prototype of the system is provided based on Oracle 8i DBMS, Apache Tomcat Web server, Java Servlets and Java Server Pages. Suggestions are provided for coping with change management issues during the implementation of the system.
29
Coulombe, Geneviève. "Rôles de la protéine tyrosine phosphatase SHP-2 dans l'inflammation intestinale et le cancer colorectal associé à la colite." Thèse, Université de Sherbrooke, 2015. http://hdl.handle.net/11143/6010.
Abstract:
SHP-2 est une tyrosine phosphatase impliquée dans la signalisation intracellulaire déclenchée par des facteurs de croissance, des cytokines pro-inflammatoires et des produits bactériens. Bien que cette phosphatase soit exprimée de manière ubiquiste et donc dans l’épithélium intestinal, son rôle dans ce tissu n'était pas connu. Afin de mieux comprendre les rôles joués par cette phosphatase dans l’intestin, nous avons généré un modèle murin de délétion conditionnelle de Shp-2 spécifiquement dans les cellules épithéliales intestinales (SHP-2[indice supérieur CEI-KO]). Nos résultats montrent que dès l'âge de 1 mois, toutes les souris expérimentales ont développé spontanément de l'inflammation au niveau du côlon. En fait, dans les cellules épithéliales intestinales, SHP-2 contrôle le niveau d’activation d’effecteurs de signalisation importants tels que les kinases ERK1/2 de même que les facteurs de transcription NFκB, STAT3 et β-caténine. En modulant ces voies de signalisation, SHP-2 contrôle des processus cellulaires primordiaux pour le maintien de l’homéostasie intestinale: la détermination des cellules à mucus et des cellules de Paneth, la composition de la flore, la perméabilité paracellulaire et la restitution épithéliale. La dérégulation de ces processus cellulaires peut expliquer l'apparition rapide d'inflammation colique chez les souris SHP-2C[indice supérieur EI-KO]. De plus, l'inflammation chronique observée chez les souris SHP-2[indice supérieur] CEI-KO entraîne avec l'âge le développement de cancer colorectal associé à la colite. Finalement, nos résultats chez l'humain montrent qu'il y a une diminution significative d'expression de SHP-2 chez les patients atteints de maladies inflammatoires intestinales comparativement aux patients témoins. Également, deux polymorphismes de PTPN11 sont retrouvés préférentiellement chez les patients atteints de colite ulcéreuse. En conclusion, nos résultats démontrent que la phosphatase SHP-2 protège l'épithélium intestinal contre l'inflammation et le cancer colorectal associé à la colite.
30
Calvo, Inês da Conceição Madaleno. "Descrição, Organização e Inventariação da colecção de Almeida Faria." Master's thesis, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa, 2011. http://hdl.handle.net/10362/6010.
Abstract:
Relatório de Estágio apresentado para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Edição de TextoO presente trabalho constitui o relatório de estágio curricular, efectivado como parte conclusiva do Mestrado em Edição de Texto, ministrado na FCSH-UNL. Este estágio, realizado na BNP-ACPC, teve como objectivos de trabalho a descrição, organização e inventariação da colecção de Almeida Faria e como objectivo final a elaboração de entradas de inventário. O presente relatório começa com uma Introdução, estando estruturado em quatro capítulos, ao longo dos quais se apresenta o trabalho realizado. O primeiro capítulo apresenta a instituição onde foi realizado o estágio tal como as bases teóricas em que o mesmo se fundamentou. No segundo capítulo é introduzido o Autor trabalhado e duas das suas obras. O terceiro capítulo apresenta todo o trabalho de descrição, organização e inventariação, enquanto o capítulo final, o quarto, expõe algumas questões e reflexões sobre o trabalho de análise efectuado. O relatório termina com uma Conclusão, sendo depois apresentadas algumas digitalizações de documentos e várias tabelas em anexo. PALAVRAS
31
Huamanchumo, Gutiérrez María del Carmen. "Nivel de conocimientos sobre autoexamen de mamas de mujeres que acuden a un centro de salud. Lima, 2014." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2017. https://hdl.handle.net/20.500.12672/6010.
Abstract:
Determina el nivel de conocimiento sobre autoexamen de mamas en mujeres. El estudio es de tipo cuantitativa, nivel aplicativo, descriptivo de corte transversal. Se realiza en el Centro de Salud Conde de la Vega Baja a mujeres entre 20 a 60 años que acuden al Centro de Salud. Se utiliza como técnica la entrevista y como instrumento un cuestionario, el cual es aplicado a una muestra de 131 mujeres.Tesis
32
Oliveira, Fernanda de Assis. "Materiais didáticos nas aulas de música : um survey com professores da Rede Municipal de Ensino de Porto Alegre - RS." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2005. http://hdl.handle.net/10183/6010.
Abstract:
Esta pesquisa teve como objetivo investigar as concepções que fundamentam o uso de materiais didáticos pelos professores de música em suas práticas pedagógico-musicais. Mais especificamente buscou identificar o que os professores consideram materiais didáticos, mapear os tipos de materiais didáticos utilizados pelos professores de música, identificar os critérios que fundamentam a seleção dos materiais didáticos, mapear o acesso aos materiais didáticos, analisar a opinião dos professores sobre os materiais didáticos disponíveis e examinar a produção dos materiais didáticos pelos professores de música. Para compreender as concepções dos professores de música sobre os materiais didáticos, me apoiei nos conceitos utilizados pelo campo de pesquisa sobre o pensamento do professor. O método escolhido foi o survey de pequeno porte, com desenho interseccional. Fizeram parte da amostra vinte professores de música atuantes no ensino fundamental da Rede Municipal de Ensino de Porto Alegre-RS. A técnica de coleta de dados foi a entrevista semi-estruturada. Os resultados revelaram as concepções dos professores sobre os materiais didáticos disponíveis, além de sugerirem as características necessárias aos materiais didáticos a serem utilizados na aula de música, no ensino fundamental.
33
Margolin, Emmanuel Aubrey. "An investigation into improved HIV-1 subtype C envelope based vaccine design." Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/6010.
34
Morais, Ana Catarina Coelho. "Prevalência da automedicação em estudantes da Universidade de Aveiro." Master's thesis, Universidade de Aveiro, 2011. http://hdl.handle.net/10773/6010.
Abstract:
Mestrado em Psicologia - Psicologia Clínica e da SaúdeSendo um problema de saúde pública mundial e uma prática bastante actual nos dias de hoje, a automedicação constitui-se como um dos principais comportamentos de risco. Nesse sentido, o presente estudo objectiva caracterizar o padrão de medicamentos não prescritos na população estudantil da Universidade de Aveiro. Para isso, realizou-se um estudo descritivo e transversal numa amostra de conveniência, constituída por 511 alunos, aos quais foi realizado em contexto de sala de aula um questionário para obtenção de informação relativa ao consumo de medicamentos não prescritos. A prevalência da automedicação foi de 44.2% e revelou-se independente do sexo, da idade e das habilitações académicas. O estudo revelou ainda que os estudantes da área da saúde se automedicam com mais frequência e que os estudantes que recorrem à automedicação o fazem por influência de familiares, amigos ou outra pessoa (53.4%) e/ou por prescrições anterior do próprio (52.3%). O presente estudo pretende contribuir para o aumento de conhecimento sobre o uso de medicamentos não prescritos. Além disso, são referidas também algumas implicações visando a promoção da saúde do estudante universitário.
As a worldwide public health problem and a fairly current practice today, self-medication was a established as a major health risk behavior. Thus, this study pretends to characterize the pattern of consumption of non-prescribed drugs among the student population at the University of Aveiro. A descriptive and transversal study was made in a convenience sample consisting of 511 students, with questionnaires being accomplished in the context of classroom a questionnaire to obtain data on consumption of non-prescribed drugs. The prevalence of self-medication was 44.2% and proved to be independent of sex, age and academic qualifications. The survey also revealed that health students self-medicate themselves more frequently and that students who self-medicate do it under the influence of family, friends or someone else (53.4%) and/or previous prescriptions of their own (52.3%). This study intends to contribute to increasing knowledge about the use of non-prescription medicines. Moreover, in the course of this work are also referred to some implications in order to promote college student health.
35
MacDonald, Elizabeth Z. "Validity and Reliability of a Photographic Method of Assessing Body Composition." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6010.
Abstract:
The LeanScreenTM app uses photographs and touchscreen technology of an iPad or iPhone to estimate body composition using the Department of Defense (DoD) prediction equations that use cirumference measurements of the neck, abdomen, waist, and hips. The purpose of this study was to determine the validity and reliability of the LeanScreenTM app in 148 weight-stable adults (82 men, 66 women) who were normal weight, overweight, or obese as defined by body mass index. The percent body fat (%BF) of each subject was estimated during one visit using dual-energy x-ray absorptiometery (DXA) as the criterion measure, and three field methods: the LeanScreenTM app, manually measured circumferences, and an OMRON bioelectical impedance (BIA) device. The %BF of each subject was determined once using DXA. Each of two administrators assessed the %BF of each subject twice using the LeanScreenTM app, manually measured circumferences, and the OMRON BIA device. When using the LeanScreenTM app, administrators assessed body composition using photographs they had taken and the photographs taken by the other administrator. Validity was established by comparing estimates of %BF from the LeanScreenTM app, manually measured circumferences, and the OMRON BIA device to %BF values obtained from DXA. Inter- and intrarater reliability was determined using mutliple measurements taken by each of two administrators. The three field methods were compared to DXA using mixed model ANOVA and Bland-Altman analyses. Analysis of the data revealed that the LeanScreenTM app, manually measured circumferences, and the OMRON BIA device significantly underestimated (p < 0.05) the %BF determined by DXA by an average of -3.26 ± 3.57 %BF, -4.82 ± 3.45 %BF, and -8.45 ± 3.48 %BF, respectively. Limits of agreement (LOA) for the LeanScreenTM app (6.99 %BF), manually measured circumferences (6.76 %BF), and the OMRON BIA device (6.82 %BF) were large. Slopes of the line-of-best-fit through the data in the Bland-Altman plots indicate that bias of %BF estimates using the LeanScreenTM app (slope = 0.06; p = 0.008) and the OMRON BIA device (slope = 0.15; p < 0.0001) increased as %BF increased. For each method of assessment, minimal variance could be attributed to different administrators peforming the assessment and each administrator performing multiple assessments. All inter- and intrarater reliability coefficients of the LeanScreenTM app, manually measured circumferences, and OMRON BIA estimates of %BF exceeded 0.99. The results of this study indicate that all three field methods of body composition assessments were highly reliable, however, these field measures are not recommended for use in the assessments of %BF due to a significant bias and large limits of agreements.
36
Wang, Yifei. "Magnetic field effects in exciplex- and exciton-based organic light emitting diodes and radical-doped devices." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/6010.
Abstract:
Organic semiconductors (OSCs) have already been shown to have great potential to play an important role in the future of clean energy generation (organic solar cells) and provide energy efficient lighting (organic light-emitting diodes, OLED). Prior research has found that the light-emission efficiency of OLED is severely limited by the magnetic state (technically the spin-configuration) of the light-emission process. In this thesis, we work on the processes using external magnetic fields that can overcome these magnetic limitations. A major focus of this research is to enhance the performance of OLED, while at the same time to unravel the scientific mechanisms by which magnetic fields act on OSCs devices.
Thermally activated delayed fluorescence (TADF) is a next-generation OLED emission technology which enables nearly 100% light-emission efficiency without using heavy precious metals. TADF characteristics depend on the probability of reverse intersystem crossing (RISC) from the triplet excited states (T1) to singlet excited states (S1). The conversion (T1 to S1) process depends strongly on spin dynamics, thus we predict a dramatic magnetic field effects (MFEs) in such TADF OLED devices. In subsequent experiments we observed that changes in TADF devices due to various forms of electrical stress can lead to enormous increases in magnetic field effects (MFEs) on the current (> 1400%) and electroluminescence (> 4000%). Our work provides a flexible and inexpensive pathway towards magnetic functionality and field sensitivity in current organic devices. Such OLED pave the way for novel magnetic sensitive OSCs devices with integrated optical, electronic and magnetic characteristics.
Organic magnetoresistance (OMAR) has been observed to alter the current and efficiency of OLED without any ferromagnetic components. Here we utilizes slight alterations to the device properties, the addition of a radical-doped functional layer, in which the spin-relaxing effects of localized nuclear spins and electronic spins interfere, to address the assumption about the importance of the hyperfine interaction and to attempt to differentiate between the different models for OMAR. A feature where the magnitude of OMAR exhibits a plateau over a wide range of doping fraction was observed at all temperatures investigated. This phenomenon is well explained by a theory in which a single dopant spin strongly interacts, by exchange, with one of the bottleneck sites. A similar can be used to explain the efficiency increases observed in organic solar cells for certain doping fractions.
37
Summers, Carl R. "Interactions in Sibling Dyads With One Preschool-Aged Child With a Disability." DigitalCommons@USU, 1992. https://digitalcommons.usu.edu/etd/6010.
Abstract:
A number of previous researchers have concluded a higher incidence of behavioral and psychological problems exists among children who are siblings of children with disabilities than among children whose siblings have no disabilities. There is some evidence in previous research that the incidence of behavioral and psychological problems may be attributable to differences in sib ling interaction patterns; specifically, frequency of interaction, imitation, agonism, dominance, and prosocial behavior. In this study, observational techniques were used to determine imitation, agonism, dominance, and prosocial behavior for two groups of children: 1) those whose siblings were disabled, and 2) those whose siblings had no disabilities. Non-observational techniques were used to assess several family factors. The Battelle Developmental Inventory was used to measure severity of disability.
ANCOVA comparisons (using family variable s as covariates) showed a higher frequency of agonism (F1,70 = 9.69, p = .003), and a low frequency of dominance (F1,64 = 5.24, p = .025) in children with a disability as opposed to their non-disabled comparisons. However, no significant differences were found among the siblings of these children. Statistically significant differences in behavior were found in comparisons between children without disabilities and children with specific disabilities (hearing impaired, Down syndrome, and developmentally delayed) for agonism (F3,70 = 6.371, p = .001) and dominance (F3,71 = 3.087, p = .033). Statistically significant differences between levels of dominance (F3,69 = 2.798, p = .046) and prosocial behavior (F3,69 = 4.206, p = .009) to the siblings without disabilities as compared to children with hearing impairments, Down syndrome, or developmental delay were found. Severity of disability was not statistically significantly related to any of the dependent variables.
Differences in interaction patterns can only be viewed as a potential contributing factor in an elevated incidence of behavior only as it relates to specific disabilities. The practice of grouping subjects from various disability groups for research purposes can be misleading.
38
Alsane, Danah. "Determining Success Factors in Interprofessional Practice with Dynamic Teams." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/6010.
Abstract:
Background: The interprofessional healthcare team is dynamic to cope with complex issues and needs existing in the healthcare environment. Understanding the important factors that predict dynamic team effectiveness helps health educators to establish team training models that focus on improving collaborative student performance that facilitates their transition to practice and helps to improve the health and system outcomes.
Objectives:1) Assess the impact of a practice-based interprofessional education (IPE) model on student attitudes and knowledge toward interprofessional teamwork.2) Evaluate predictors associated with team effectiveness among dynamic student teams participating in a practice-based IPE setting.
Methods: This was an exploratory cross-sectional study using a multi-measures approach to evaluate dynamic student teams in a real-life environment. Measures include self-reported surveys, a knowledge test, video recording of team encounters, and an assessment of team healthcare plans. Regression analyses were conducted to assess predictors associated with team effectiveness.
Results: The sample size was equal to 72 students and 48 clients who participated in 100 clinical sessions. Among the evaluation approaches, faculty and client ratings were robust to evaluate dynamic student team effectiveness (R-squared = 53.6 % and 41.7 %, respectively). The significant team predictors were related to team size and clinic site.
Conclusion: Practice-based IPE models are an excellent opportunity for health professions students to improve their skills, knowledge, and attitudes toward interprofessional teamwork, preparing them for the collaborative-practice environment. The results of this study suggests that in practice-based IPE models faculty and client ratings can be used as an approach to evaluate dynamic student team effectiveness.
39
Dodge, Tanya A. "Parental Involvement in Individual Education Plan Development for Students with Significant Intellectual Disabilities." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/6010.
Abstract:
Research indicates a connection between successful outcomes for students with significant intellectual disabilities and the individual education program (IEP) team's efforts in the IEP development process. However, little research has been conducted on the perceptions of parents and teachers of students with significant disabilities about parent participation in the IEP development process. Therefore, the purpose of this phenomenological study was to explore parent and teacher perceptions of parent participation in the IEP development process. The conceptual framework of this study was ecological design theory, based on Bronfenbrenner's theory of human development and Neal and Neal's theory of networked systems. Participants consisted of 4 parents and 5 teachers of students with significant intellectual disabilities who have participated in the IEP development process. The interviews conducted with participants were analyzed for patterns and themes. Findings showed that teacher descriptions centered on actions connected with fulfillment of state guidelines, which create the setting in which the IEP development takes place. Parent participants acknowledged compliance to state guidelines based on teacher actions, but parent commentary was centered on elements of the parent-teacher relationship. Responses indicated that actions to strengthen the school-parent partnership may improve parent and teacher experiences of IEP development. This study contributes to positive social change by providing administrators and teachers information to better support the IEP development process toward improved outcomes for students with significant intellectual disabilities.
40
Salvador, Stephan <1989>. "Evoluzione normativa nel mondo dello sport. Dalla sentenza Walrave al Financial Fair Play." Master's Degree Thesis, Università Ca' Foscari Venezia, 2015. http://hdl.handle.net/10579/6010.
Abstract:
La tesi vuole mostrare l'evoluzione normativa in ambito sportivo partendo dalla sentenza Walrave del 1974 arrivando alla prima applicazione del Financial Fair Play.
In questo elaborato verranno affrontate le più importanti sentenze che hanno influenzato il mondo dello sport completandole con la parallela evoluzione legislativa italiana.
L'analisi del libro bianco sullo sport e di "The Economic and Legal Aspects of Transfer of Players" condurrà all'analisi del Financial Fair Play.
La tesi vuole dare evidenza dell’importanza economica del mondo dello sport professionistico partendo dal presupposto che, almeno in Italia, solamente negli ultimi anni si sta assistendo a questo fondamentale cambio di mentalità per permettere a questa attività economica di sfruttare le sue enormi potenzialità.
41
Rowlinson, Zachary James. "Dismantling the face in Thomas Pynchon's fiction." Thesis, University of Sussex, 2016. http://sro.sussex.ac.uk/id/eprint/60110/.
Abstract:
Thomas Pynchon has often been hailed, by those at wont to make such statements, as the most significant American author of the past half-century. What is indisputable about this simultaneously beguiling and frustrating, prodigiously sophisticated and irrevocably juvenile, not to say admired and reviled writer, is that his fiction has inspired critical readings that are now as appositely voluminous as his novels themselves. Yet no prior critical effort does full justice to the importance of the face in the work of this notoriously “faceless” author, who even had a brown paper bag over his head when depicted in cartoon form on The Simpsons. In light of this oversight, this thesis seeks to address what might be called—to borrow from his 1990 novel, Vineland—the ‘not-yet-come-to-terms-with face' in Pynchon's corpus. Though always driven by the workings of Pynchon's writing, various theorists—such as Theodor Adorno, Walter Benjamin, Erving Goffman, and Emmanuel Levinas—are called-upon throughout this study in order to aid the conceptualisation of this ‘not-yet-come-to-terms with face'. Particular inspiration is taken from Gilles Deleuze and Félix Guattari's call to ‘dismantle the face' in A Thousand Plateaus. Albeit not in strict adherence to this summons, the first three chapters of this project butcher the face into its dominant component features: eyes, nose, and mouth. These features—as well as the central issues of the final two chapters, the mask and the face respectively—are then traced across Pynchon's entire oeuvre, including his most recent novel, Bleeding Edge, published when this project was already underway. What emerges is a picture of the integral role the face plays in Pynchon's manifold concerns: surveillance, surgery, dentistry, identity, cinema, drugs, the senses, and so on. This thesis ultimately contends that although frequently defaced and effaced in Pynchon's writing, the face is nevertheless a prime locus at which ethical and political possibility surface.
42
Васильєва, Тетяна Анатоліївна, Татьяна Анатольевна Васильева, and Tetiana Anatoliivna Vasylieva. "Принципы оценки эффективности инвестиций." Thesis, Сумський державний університет, 1997. http://essuir.sumdu.edu.ua/handle/123456789/60710.
43
Bowrin, A. "Corporate governance in commonwealth caribbean banks." Thesis, Українська академія банківської справи Національного банку України, 2007. http://essuir.sumdu.edu.ua/handle/123456789/60610.
Abstract:
Корпоративне управління зараз є головним питанням у світовому порядку денному
кілька серйозних фінансових скандалів у США, Великобританії, Франції та інших
розвинені країни. У Карибському басейні, де компанії сильно покладаються на борг
банківський сектор тісно бере участь у процесі КГ в
кількість способів.Corporate governance is now a major issue on the global agenda following several high-profile financial scandals in the USA, UK, France and other developed countries. In the Caribbean, where companies rely heavily of debt financing, the banking sector is intimately involved in the process of CG in a number of ways.
44
Васильєва, Тетяна Анатоліївна, Татьяна Анатольевна Васильева, Tatiana Anatolevna Vasyleva, Сергій Вячеславович Лєонов, Сергей Вячеславович Леонов, and Serhii Viacheslavovych Lieonov. "Суб’єктно-об’єктний взаємозв’язок банківської системи та ринку інноваційного інвестування." Thesis, Мрія-1, 2009. http://essuir.sumdu.edu.ua/handle/123456789/60110.
Abstract:
Однією з причин неефективного фінансово-кредитного забезпечення
інноваційного процесу є невпорядкованість руху капіталу від його власників
до споживачів, неокресленість інституційного й правового поля та ринкового
простору акумуляції ресурсів, їх трансформації в продуктивний капітал, невідповідність між попитом та пропозицією, а також неврегульованість дій
учасників комерційних угод в цій сфері. Для вирішення цієї проблеми пропонується в структурі фінансового ринку виокремити ринок інноваційного інвестування та визначити його як сукупність економічних відносин між постачальниками інвестиційних ресурсів, їх споживачами (суб’єктами інноваційної діяльності), посередниками з приводу акумуляції розрізнених інвестиційних потоків та трансформації їх у продуктивний капітал на основі взаємодії попиту та пропозиції в межах інституційного й правового поля з метою
подальшого використання його для виробництва інновації та еквівалентного
обміну платоспроможного попиту покупця права володіння, користування і
розпорядження нею на споживчу цінність, укладену в ній.
45
Деревянко, Богдан Володимирович, Богдан Владимирович Деревянко, and Bohdan Volodymyrovych Derevianko. "Пропозиції змін Господарського та Податкового кодексів України." Thesis, Хмельницький університет управління та права, 2013. http://essuir.sumdu.edu.ua/handle/123456789/60810.
Abstract:
Для стимулювання економічного інтересу наявних і потенційних інвесторів, які передають українським суб’єктам господарювання перспективні майнові активи, пропонуємо закріпити у ГК України їх визначення, а в ПК України – їх визначення та податкові пільги для інвесторів. Можна запропонувати норму, згідно з якою при обчисленні витрат, понесених платником податку на прибуток, вартість прогресивних майнових активів обраховується у подвійному розмірі (у звичайному випадку – в одинарному).
У відповідність із нормами ГК України та ПК України у майбутньому повинні бути приведені закони та підзаконні НПА України.To stimulate the economic interest of existing and potential investors who transfer promising property assets to Ukrainian business entities, we propose to fix them in the GK of Ukraine, and in the PC of Ukraine - their definition and tax privileges for investors. It is possible to propose a norm according to which in the calculation of expenses incurred by the taxpayer, the cost of progressive property assets is calculated in double size (in the usual case - in single). In accordance with the norms of the Civil Code of Ukraine and the PC of Ukraine in the future, the laws and subordinate legislation of the NPO of Ukraine should be brought.
46
Нестеренко, Ю. В. "Застосування функцій в економічній теорії." Thesis, Українська академія банківської справи Національного банку України, 2006. http://essuir.sumdu.edu.ua/handle/123456789/60210.
Abstract:
Функції знаходять широке застосування в економічній теорії та
практиці. Спектр функцій, що використовуються в економіці, достатньо
широкий: від лінійних до функцій, які одержуються за певним алгоритмом за
допомогою так званих рекурентних співвідношень, що пов’язують стани
об’єктів, які вивчаються в різни періоди часу.Functions are widely used in economic theory and practice. The spectrum of functions used in the economy is sufficient wide: from linear to functions that are obtained by a certain algorithm for help with the so-called recurring relations that bind states objects that are studied in different periods of time.
47
Нідзельська, І. А. "Наслідки волатильності обмінного курсу гривні для банківської системи." Thesis, Українська академія банківської справи Національного банку України, 2008. http://essuir.sumdu.edu.ua/handle/123456789/60910.
Abstract:
Волатильність обмінного курсу в умовах надання більшої гнучкості
національній валюті може сприяти як отриманню позитивного ефекту, так і
призвести до певних втрат для суб’єктів валютного ринку.Volatility of the exchange rate in conditions of greater flexibility the national currency can contribute both to a positive effect, and so on lead to certain losses for the subjects of the foreign exchange market.
48
Жуков, Е. Ф. "Ипотечный кризис в США и его влияние на накопление денежного капитала в мировой экономике." Thesis, Українська академія банківської справи Національного банку України, 2008. http://essuir.sumdu.edu.ua/handle/123456789/60310.
Abstract:
Предшественником ипотечного кризиса в США был Азиатский
финансовый кризис, который негативно повлиял на рынок ценных бумаг и
банковскую систему стран Юго-Восточной Азии. Дефолт в августе 1998 г.
в России привел к развертыванию глубокого кризиса банковской системы и
краху крупных коммерческих банков.
49
Kho, Kim Lee. "Attachment-based family intervention for childhood anxiety and depression: A mixed methods evaluation." Thesis, Kho, Kim Lee (2020) Attachment-based family intervention for childhood anxiety and depression: A mixed methods evaluation. Professional Doctorate thesis, Murdoch University, 2020. https://researchrepository.murdoch.edu.au/id/eprint/60110/.
Abstract:
Parent-child attachment and family relationships significantly contribute to the development of childhood depression and anxiety disorders. However, clinical applications of such findings are currently limited. The overarching objective of this dissertation was to conduct a pilot trial and examine the feasibility of a novel attachment-based family intervention, Behaviour Exchange Systems Therapy- Foundations (BEST-F) in treating internalising symptoms of depression and anxiety disorders in children aged between 3 and 11 years. The first study systematically reviewed studies to describe core features of existing psychological interventions referring to themselves as ‘attachment-based’, which revealed that there were limited attachment-based interventions primarily aimed at improving child and adolescent mental health outcomes. Empirical study two reported quantitative outcomes of an uncontrolled study of 17 families who undertook BEST-F based on parent-report CBCL measures completed at four-timepoints (baseline, pre-, post-intervention, and follow-up). Empirical study three explored qualitative outcomes reported by participants. Results suggested that BEST-F reduced child internalising symptoms by 1 to 1.2 standard deviations, and moved children from the borderline clinical to normal range. Notably, additional reduction in symptoms were reported two months after cessation of treatment. Furthermore, there were reductions in child externalising symptoms and other problems, parental mental health symptoms and disorganised caregiving behaviours. Qualitative reports suggested that participants derived considerable benefits at both dyadic and systemic levels. Finally, translational study four evaluated a BEST training program to ensure effective dissemination of the intervention model to clinical practice. Results revealed that the training was well-received and trainees reported further development in clinical skills including family systems approach, risk assessment and management, and facilitation skills. The findings add to the limited body of literature on attachment-based family interventions designed to treat childhood depression and anxiety disorders.
50
Jackson, John Anthony. "Carbonate cementation in sandstones of the Plover Formation, North West Shelf, W.A." Thesis, Queensland University of Technology, 2012. https://eprints.qut.edu.au/60110/1/John_Jackson_Thesis.pdf.
Abstract:
Ancient sandstones include important reservoirs for hydrocarbons (oil and gas), but, in many cases, their ability to serve as reservoirs is heavily constrained by the effects of carbonate cements on porosity and permeability. This study investigated the controls on distribution and abundance of carbonate cements within the Jurassic Plover Formation, Browse Basin, North West Shelf, Australia. Samples were analysed petrographically with point counting of 59 thin sections and mineralogically with x-ray diffraction from two wells within the Torosa Gas Field. Selected samples were also analysed for stable isotopes of O and C. Sandstones are classified into eleven groups. Most abundant are quartzarenites and then calcareous quartzarenites. Lithology ranged between sandstones consisting of mostly quartz with scant or no carbonate in the form of cement or allochems, to sandstones with as much as 40% carbonate. The major sources of carbonate cement in Torosa 1 and Torosa 4 sandstones were found to be early, shallow marine diagenetic processes (including cementation), followed by calcite cementation and recrystallisation of cements and allochems during redistribution by meteoric waters. Blocky and sparry calcite cements, indicative of meteoric environments on the basis of stable isotope values and palaeotemperature assessment, overprinted the initial shallow marine cement phase in all cases and meteoric cements are dominant. Torosa 4 was influenced more by marine settings than Torosa 1, and thus has the greater potential for calcite cement. The relatively low compaction of calcite-cemented sandstones and the stable isotope data suggest deep burial cementation was not a major factor. Insufficient volcanic rock fragments or authigenic clay content infers alteration of feldspars was not a major source of calcite. Very little feldspar is present, altered or otherwise. Hence, increased alkalinity from feldspar dissolution is not a contributing factor in cement formation. Increased alkalinity from bacterial sulphate reduction in organic–rich fine sediments may have driven limited cementation in some samples. The main definable and significant source of diagenetic marine calcite cement originated from original marine cements and the nearby dissolution of biogenic sources (allochems) at relatively shallow depths. Later diagenetic fluids emplaced minor dolomite, but this cement did not greatly affect the reservoir quality in the samples studied.