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1

Mezeyová, Ivana, Alžbeta Hegedűsová, Marcel Golian, Alena Andrejiová, Miroslav Šlosár, and Ján Mezey. "Influence of Microgreens Biofortification with Selenium on Their Quantitative and Qualitative Parameters." Agronomy 12, no. 5 (April 30, 2022): 1096. http://dx.doi.org/10.3390/agronomy12051096.

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The study monitored the effect of differentiated mineral nutrition of microgreens species by solution of sodium selenate (2 mg Se/L) on the content of Se, chlorophylls, and other minerals. Chlorophylls were measured spectrophotometrically, Se by electrothermal atomic absorption method (ETAAS) with Zeeman-effect background and elements' concentration was performed by a dual Inductively coupled plasma atomic emission spectroscopy (ICP-OES) iCAP7600 instrument. The content of selenium in fresh weight moved on average from 0.013 to 12.556 μg/g. Selenisation increased the content of Se in all tested species significantly (p < 0.05) without impacting yield. The content of chlorophyll a moved from 249.9 mg/kg (Mizuna) to 604.4 mg/kg (Arugula) with significant differences between the species, without significance (p ≤ 0.05) between tested variants. The influence of selenisation on other minerals significantly differed (p < 0.05) due to the genetic variability. A significant (p ≤ 0.05) increase in Ca was observed in green basil (10.7%) and cress (20.9%); of Fe in green basil (1.6%) and cress (40.9%); of K in arugula (1.6%), green basil (3.9%) and cress (2.8%); of Zn in arugula (2.6%), green basil (8.6%), cress (2.7%) and radish (5.9%); and of Ba in green basil (5.6%) and cress (23.9%).
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Hinduja, Archana, Jamil Dibu, Eugene Achi, Anand Patel, Rohan Samant, and Shadi Yaghi. "Nosocomial Infections in Patients With Spontaneous Intracerebral Hemorrhage." American Journal of Critical Care 24, no. 3 (May 1, 2015): 227–31. http://dx.doi.org/10.4037/ajcc2015422.

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Background Nosocomial infections are frequent complications in patients with intracerebral hemorrhage. Objectives To determine the prevalence, risk factors, and outcomes of nosocomial infections in patients with intracerebral hemorrhage. Methods Prospectively collected data on patients with spontaneous intracerebral hemorrhage between January 2009 and June 2012 were retrospectively reviewed. Patients who had nosocomial infection during the hospital stay were compared with patients who did not. Poor outcome was defined as death or discharge to a long-term nursing facility. Results At least 1 nosocomial infection developed in 26% of 202 patients with intracerebral hemorrhage. The most common infections were pneumonia (18%), urinary tract infection (12%), meningitis or ventriculitis (3%), and bacteremia (1%). On univariate analysis, independent predictors of nosocomial infection were intraventricular hemorrhage, hydrocephalus, low score on the Glasgow Coma Scale at admission, hyperglycemia at admission, and treatment with mechanical ventilation. On multivariate regression analysis, the only significant predictor of nosocomial infection was intraventricular hemorrhage (odds ratio, 5.4; 95% CI, 1.2–11.4; P = .02). Patients with nosocomial infection were more likely than those without to require a percutaneous gastrostomy tube (odds ratio, 33.1, 95% CI, 23.3–604.4; P &lt; .001) and to have a longer stay in the intensive care unit or hospital without a significant increase in mortality. Patients with nosocomial pneumonia were also more likely to have a poor outcome (P &lt; .001). Conclusion Pneumonia was the most common infection among patients with intracerebral hemorrhage.
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Genanaw, Wubalem, Girum Gebremeskel Kanno, Dawit Derese, and Mekonnen Birhanie Aregu. "Effect of Wastewater Discharge From Coffee Processing Plant on River Water Quality, Sidama Region, South Ethiopia." Environmental Health Insights 15 (January 2021): 117863022110610. http://dx.doi.org/10.1177/11786302211061047.

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In Ethiopia, most of the coffee processing plants are generating large amounts of wastewater with high pollutant concentrations and discharge directly into the water bodies untreated or partially treated. The main objective of this study was to assess the effects of coffee wastewater discharged to river water quality using physicochemical parameters and macro-invertebrate indices. This study was conducted from November to the end of December 2019. Ten wastewater and river water samples were taken from coffee the processing plant and river. The macro-invertebrate samples were collected by kick sampling technique using a standard hand net. Shannon and Simpson diversity indices were examined at 3 sampling stations. The Pielou evenness index was also determined. It was found that except for TDS all the parameters of the raw wastewater and river water did not comply with the international discharge limit. The mean concentration of Faro coffee processing plant wastewater were BOD5 (2409.6 ± 173.1 mg/L), COD (4302 ± 437 mg/L), TSS (2824.6 ± 428.4 mg/L), TDS (3226 ± 623.6 mg/L), and TS (4183.3 ± 432.9 mg/L). Whereas from Bokaso coffee processing plant were BOD5 (3770 ± 604.4 mg/L), COD (4082.6 ± 921.9 mg/L), TSS (2766 ± 501.7 mg/L), TDS (3017 ± 747.6 mg/L), and TS (3874 ± 471.1 mg/L). A total of 392 macroinvertebrates belonging to 24 families and 7 orders were collected. The benthos assemblage communities in this river were 40, 56, and 296 at downstream 1, downstream 2, and upstream respectively. The value of the Simpson diversity index varies from 0.4 to 0.75. In the same manner, the value of the Shannon diversity index also varied from 0.5 to 1.36. Most of the physicochemical parameters of the raw wastewater were beyond the national and international discharge limits. The quality of Orsha river water downstream was more adversely affected compared to upstream.
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Carey, Sean, and Kathleen Maguire-Zeiss. "60404 HIV Tat Induced Neuroinflammation." Journal of Clinical and Translational Science 5, s1 (March 2021): 3. http://dx.doi.org/10.1017/cts.2021.410.

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ABSTRACT IMPACT: Demonstrate the role of astrocyte released MMPs in response to pathogenic HIV protein Tat. OBJECTIVES/GOALS: In the presence of the pathogenic HIV protein Tat, astrocytes have been demonstrated to adopt an inflammatory phenotype as well as release extracellular matrix degrading enzymes, MMPs. Our work aims to identify whether MMPs alter perineuronal net integrity and working memory in a mouse model of Tat-induced neuroinflammation. METHODS/STUDY POPULATION: Stereotaxic Injection: C57BL6/J mice were injected bilaterally with HIV-1 IIIB Tat 5ug in 5uL or Vehicle (0.2M KCl, 5mM DTT, 50mM Tris, pH 8.0), into the hippocampus (CA1; -1.9mm AP, ±1.6mm ML, -1.5mm DV from pial surface). All outcome measurements were performed 14-days post injection. Behavior: T-maze was used to assess working memory following Tat exposure. qRT-PCR: TaqMan probes were used according to manufacturer on extracted whole hippocampus mRNA. IF: GFAP and CD68 immunofluorescence was used to determine inflammation post injection. Inhibitory interneurons (parvalbumin positive) and peri-neuronal nets (WFA positive) were quantified. WB: Synaptosomes from whole hippocampi (Syn-PER) were isolated and synaptic excitatory markers were quantified (PSD-95, synaptophysin, GluR2a). RESULTS/ANTICIPATED RESULTS: Tat exposure resulted in impairments in working memory as measured by T-maze alternations and an increase in hippocampal mRNA expression of MMP-13 and IL-1β, indicative of neuroinflammation. We also noted an increase in GFAP+ injection site width 14 days post-Tat injection, suggesting robust gliosis. While there were no changes in the excitatory pre and post synaptic markers we found a significant decrease in the percent of PV+ interneurons with peri-neuronal nets (PNNs) following Tat exposure. Taken together, this preliminary data supports a role for inflammation and PNN integrity in Tat-induced alterations in working memory. DISCUSSION/SIGNIFICANCE OF FINDINGS: Our findings suggest that Tat contributes to cognitive impairment and that astrogliosis with elevated MMP-13 facilitates the degradation of peri-neuronal nets (PNNs) within the hippocampus. Since PNN degradation can alter neuronal circuitry future studies will focus on Tat-induced changes in hippocampal signaling.
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Majer, Vladimir, Lü Hui, Rosa Crovetto, and Robert H. Wood. "Volumetric properties of aqueous 1-1 electrolyte solutions near and above the critical temperature of water I. Densities and apparent molar volumes of NaCl(aq) from 0.0025 mol·kg−1 to 3.1 mol·kg−1, 604.4 K to 725.5 K, and 18.5 MPa to 38.0 MPa." Journal of Chemical Thermodynamics 23, no. 3 (March 1991): 213–29. http://dx.doi.org/10.1016/s0021-9614(05)80180-6.

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6

Kim, Doman, Jun-Seong Park, Hee-jung Lim, Thi Thanh Hanh Nguyen, Nahyun M. Kim, Ghahyun J. Kim, Kyeonghwan Hwang, and Atsuo Kimura. "Enhancement of water soluble wheat bran polyphenolic compounds using different steviol glucosides." Functional Foods in Health and Disease 6, no. 10 (October 31, 2016): 650. http://dx.doi.org/10.31989/ffhd.v6i10.302.

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Background: Production of wheat bran (WB) for human consumption is estimated to be about 90 million tons per year. WB contains abundant source of dietary fiber, minerals, vitamins, and bioactive compounds. WB is a by-product of milling and contains abundant source carbohydrate (60%), protein (12%), fat (0.5%), minerals (2%), and bioactive compounds such as phenolic acids, arabinoxylans, flavonoids, caroteinoids alkylresorcinol and phytosterols. These are known for health promoting properties such as controlling glycemic index, reducing plasma cholesterol level, and reducing the human colon cancer cell growth antioxidant, antimicrobial, anti-inflammatory, and anticarcinogenic activities. Several terpene glycosides such as mogroside V, paenoiflorin, geniposide, rubusoside (Ru), stevioside (Ste), rebaudioside A (RebA), steviol monoside, and stevioside glucoside have been discovered to enhance the solubility of a number of pharmaceutically and medically important compounds that normally show poor solubility in water.Context and purpose of this study: In this study, to increase soluble extraction of polyphenol compounds of WB using Ru, the expression of β-galactosidase from Thermus thermophilus was optimized with different E. coli hosts and with different concentration of lactose inducer instead of isopropyl-1-thio-β-D-galactopyranoside (IPTG) for industrial production. Furthermore, the effect of different steviol glucosides (Ru, Ste, RebA, and SG) on the enhancement of polyphenol compounds extraction from wheat bran was studied. Results: β-galactosidase from Thermus thermophilus was used for the specific conversion of stevioside (Ste) to rubusoside (Ru) with 92% productivity. The enzyme was optimized to be expressed in E. coli. With 7 mM lactose, the β-galactosidase activity expressed was 34.3, 14.2, or 34.4 ± 0.5 U/mL in E. coli BL21(DE3)plysS, Rosetta(DE3)plysS, or BL21(DE3) at 37°C, and 9.8 ± 0.2, 7.0 ± 0.5, or 7.4 ± 0.2 U/mL at 28°C, respectively. The expression of β-galactosidase was dependent on the lactose concentration and the highest activity was obtained with the conditions of 5 mM lactose in E. coli Rosetta(DE3)plysS, 53.3 ± 1.5 U/mL. 78% of the mesophilic proteins was eliminated by heating at 70°C for 15 min with 89% β-galactosidase activity recovery. The total polyphenol content of WB extracted by water, Ru, Ste, rebaudioside A (RebA), and steviol glucosides (SG) were 533.8 ± 9.6 µg/mL, 633.3 ± 1.25 µg/mL, 604.4 ± 10.1 µg/mL, 654.8 ± 26.5 µg/mL, and 601.2 ± 33.4 µg/mL, respectively. The DPPH radical scavenging activity prepared by water, Ru, Ste, RebA, and SG extraction were 8.76 ± 0.3 mg/mL, 4.87 ± 0.3 mg/mL, 5.34 ± 0.22 mg/mL, 7.27 ± 0.1 mg/mL, and 7.82 ± 0.02 mg/mL, respectively.Conclusions: To increase soluble extraction of polyphenol compounds of WB using Ru, the expression of β-galactosidase from Thermus thermophilus was optimized with different E. coli hosts and with different concentration of lactose inducer instead of isopropyl-1-thio-β-D-galactopyranoside (IPTG) for industrial production of the enzyme. The highest antioxidant activity was shown in WB extracted by Ru. The number of glucosyl units attached to steviol can possibly affect the efficiency of antioxidant activity of WB extracted by steviol glucosides. Keywords: Rubusoside, ß-galactosidase, lactose induction, immobilized enzyme, wheat bran, steviol glucosides
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Narang, Diksha. "Book review: Piliavsky, A (Ed.), Nobody’s People: Hierarchy as Hope in a Society of Thieves." Journal of Human Values 27, no. 3 (September 2021): 271–73. http://dx.doi.org/10.1177/09716858211039969.

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8

PEYTON JONES, SIMON. "4 Declarations and Bindings." Journal of Functional Programming 13, no. 1 (January 2003): 39–66. http://dx.doi.org/10.1017/s0956796803000613.

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4.1 Overview of Types and Classes 404.2 User-Defined datatypes 454.3 Type Classes and Overloading 494.4 Nested Declarations 554.5 Static Semantics of Function and Pattern Bindings 604.6 Kind Inference 66
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9

Vorselaars, Bart, Štěpán Růžička, David Quigley, and Michael P. Allen. "Correction: Folding kinetics of a polymer." Physical Chemistry Chemical Physics 19, no. 7 (2017): 5674–76. http://dx.doi.org/10.1039/c7cp90027a.

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10

Majer, Vladimir, Lü Hui, Rosa Crovetto, and Robert H. Wood. "Volumetric properties of aqueous 1-1 electrolyte solutions near and above the critical temperature of water II. Densities and apparent molar volumes of LiCl(aq) and NaBr(aq) at molalities from 0.0025 mol·kg−1 to 3.0 mol·kg−1, temperatures from 604.4 K to 725.5 K, and pressures from 18.5 MPa to 38.0 MPa." Journal of Chemical Thermodynamics 23, no. 4 (April 1991): 365–78. http://dx.doi.org/10.1016/s0021-9614(05)80091-6.

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Alfred, O. Ubalua, and Mbanaso Ena. "Somatic embryogenesis in two Nigerian cassava cultivars (Sandpaper and TMS 60444)." Journal of Evolutionary Biology Research 6, no. 3 (October 30, 2014): 9–12. http://dx.doi.org/10.5897/jebr2013.0054.

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He, Bing, and Lana Garmire. "Prediction of repurposed drugs for treating lung injury in COVID-19." F1000Research 9 (June 15, 2020): 609. http://dx.doi.org/10.12688/f1000research.23996.1.

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Background: Coronavirus disease (COVID-19) is an infectious disease discovered in 2019 and currently in outbreak across the world. Lung injury with severe respiratory failure is the leading cause of death in COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there still lacks efficient treatment for COVID-19 induced lung injury and acute respiratory failure. Methods: Inhibition of angiotensin-converting enzyme 2 (ACE2) caused by the spike protein of SARS-CoV-2 is the most plausible mechanism of lung injury in COVID-19. We performed drug repositioning analysis to identify drug candidates that reverse gene expression pattern in L1000 lung cell line HCC515 treated with ACE2 inhibitor. We confirmed these drug candidates by similar bioinformatics analysis using lung tissues from patients deceased from COVID-19. We further investigated deregulated genes and pathways related to lung injury, as well as the gene-pathway-drug candidate relationships. Results: We propose two candidate drugs, COL-3 (a chemically modified tetracycline) and CGP-60474 (a cyclin-dependent kinase inhibitor), for treating lung injuries in COVID-19. Further bioinformatics analysis shows that 12 significantly enriched pathways (P-value <0.05) overlap between HCC515 cells treated with ACE2 inhibitor and human COVID-19 patient lung tissues. These include signaling pathways known to be associated with lung injury such as TNF signaling, MAPK signaling and chemokine signaling pathways. All 12 pathways are targeted in COL-3 treated HCC515 cells, in which genes such as RHOA, RAC2, FAS, CDC42 have reduced expression. CGP-60474 shares 11 of 12 pathways with COL-3 and common target genes such as RHOA. It also uniquely targets other genes related to lung injury, such as CALR and MMP14. Conclusions: This study shows that ACE2 inhibition is likely part of the mechanisms leading to lung injury in COVID-19, and that compounds such as COL-3 and CGP-60474 have potential as repurposed drugs for its treatment.
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He, Bing, and Lana Garmire. "Prediction of repurposed drugs for treating lung injury in COVID-19." F1000Research 9 (August 26, 2020): 609. http://dx.doi.org/10.12688/f1000research.23996.2.

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Background: Coronavirus disease (COVID-19) is an infectious disease discovered in 2019 and currently in outbreak across the world. Lung injury with severe respiratory failure is the leading cause of death in COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there still lacks efficient treatment for COVID-19 induced lung injury and acute respiratory failure. Methods: Inhibition of angiotensin-converting enzyme 2 (ACE2) caused by the spike protein of SARS-CoV-2 is the most plausible mechanism of lung injury in COVID-19. We performed drug repositioning analysis to identify drug candidates that reverse gene expression pattern in L1000 lung cell line HCC515 treated with ACE2 inhibitor. We confirmed these drug candidates by similar bioinformatics analysis using lung tissues from patients deceased from COVID-19. We further investigated deregulated genes and pathways related to lung injury, as well as the gene-pathway-drug candidate relationships. Results: We propose two candidate drugs, COL-3 (a chemically modified tetracycline) and CGP-60474 (a cyclin-dependent kinase inhibitor), for treating lung injuries in COVID-19. Further bioinformatics analysis shows that 12 significantly enriched pathways (P-value <0.05) overlap between HCC515 cells treated with ACE2 inhibitor and human COVID-19 patient lung tissues. These include signaling pathways known to be associated with lung injury such as TNF signaling, MAPK signaling and chemokine signaling pathways. All 12 pathways are targeted in COL-3 treated HCC515 cells, in which genes such as RHOA, RAC2, FAS, CDC42 have reduced expression. CGP-60474 shares 11 of 12 pathways with COL-3 and common target genes such as RHOA. It also uniquely targets other genes related to lung injury, such as CALR and MMP14. Conclusions: This study shows that ACE2 inhibition is likely part of the mechanisms leading to lung injury in COVID-19, and that compounds such as COL-3 and CGP-60474 have potential as repurposed drugs for its treatment.
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Moscatelli, F. A., D. E. Murnick, and R. B. Robinson. "Field isotope shifts in the 3p54p-3p55d 604.3 nm transit argon I." Journal of Physics B: Atomic, Molecular and Optical Physics 21, no. 16 (August 28, 1988): L495—L499. http://dx.doi.org/10.1088/0953-4075/21/16/001.

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Парамонов, А. С. "LABORATORY STUDIES OF PROPERTIES OF SOFT MAGNETIC POWDER COMPOSITE MATERIALS." Южно-Сибирский научный вестник, no. 6(40) (December 20, 2021): 220–24. http://dx.doi.org/10.25699/sssb.2021.40.6.028.

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Изучение эффективности использования электротехнических материалов является актуальной проблемой в области изготовления электрических машин. Одним из важнейших аспектов изготовления электрических машин является проектирование магнитной системы машины. В качестве магнитной системы используют магнитопроводы из различных магнитомягких материалов. Эти материалы отличаются магнитной проницаемостью и удельными магнитными потерями. Данные параметры материалов влияют на нагрев, размер, стоимость и эффективность электрической машины. В целях экономии экспериментальная оценка параметров магнитомягких материалов производится на заготовках различных форм и размеров, на специальных измерительных стендах, согласно международным энергетическим стандартам. В данной статье предлагается экспериментальная установка для лабораторных исследований магнитных свойств магнитомягких материалов, методом кольцевых заготовок, в соответствие со стандартом МЭК-60404-6. В составе установки используется только стандартное недорогое оборудование. Необходимый коэффициент формы магнитной индукциидостигается последовательной коррекциейнапряжения вторичной обмотки с помощью цифрового регулятора. Подход к программной реализации алгоритма последовательной коррекции напряжения вторичной обмотки изложен в статье. С помощью предлагаемой установки проведено исследование свойств образца из магнитомягкого композиционного порошкового материала Somaloy 700-3p (800 MPa) и сравнение результатов с каталожными данными производителя. По итогам работы выявлено, что с помощью предлагаемойустановки могут производитьсяизмерения свойств магнитомягких материалов, в соответствие со стандартом МЭК-60404-6 с необходимой точностью. Предлагаемая установка может быть использована как в качестве учебного стенда, так и в качестве измерительной установки для идентификации свойств магнитомягких материалов при проектировании электрических машин. The study of the efficiency of using electrical materials is of great interest in the field of manufacturing electrical machines. One of the most important aspects of the manufacture of electrical machines is the design of the magnetic cores of the machine. Magnetic cores made of various magnetically soft materials are used as a magnetic system. These materials differ in magnetic permeability and specific magnetic losses. These material parameters affect the heating, size, cost and efficiency of electric machines. In order to reduce expenses, the experimental evaluation of the parameters of soft magnetic materials is carried out on samples of various shapes and sizes, on special experimental setups, in accordance with international electrotechnical standards. This article proposes an experimental setup for laboratory studies of the magnetic properties of soft magnetic materials by the method of ring specimens, in accordance with the IEC-60404-6 standard. The setup uses only standard inexpensive equipment. The required shape factor of the magnetic flux density is achieved by sequential correction of the secondary winding voltage using a digital regulator. The approach to the software implementation of the algorithm for sequential correction of the secondary winding voltage is described in the article. The proposed experimental setup was used to study the properties of a sample made of a soft magnetic composite powder material Somaloy 700-3p (800 MPa) and compare the results with the manufacturer's catalog data. Based on the results of the work, it was revealed that the proposed setup can be used to measure the properties of soft magnetic materials in accordance with the IEC-60404-6 standard with the required accuracy. The proposed experimental setup can be used both as a training stand and as a measuring installation for identifying the properties of soft magnetic materials in the design of electrical machines.
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Minkwitz, Rolf, and Thomas Hertel. "Kristallstruktur von Acetat-acidium- hexafluoroantimonat CH3C(OH)2SbF6 Crystal Structure of Acetate Acidium Hexafluoroantimonate CH3C(OH)2SbF6." Zeitschrift für Naturforschung B 52, no. 10 (October 1, 1997): 1283–86. http://dx.doi.org/10.1515/znb-1997-1022.

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The crystal structure of acetate acidium hexafluoroantimonate CH3C(OH)2+SbF6− has been determined on single crystals with MoKα radiation at -83 °C. The structure is triclinic, space group P1̄, Z = 2, and the cell dimensions are a = 604.7(1), b = 692.3(3), c = 951.7(2) pm, α = 102.13(2)°, β = 106.53(2)°, γ = 99.27(2)°. In the CH3C(OH)2+ cation the C-C distance is 147.8(6) pm , the C -O distances are 125.1(6) and 129.1(5) pm. The SbF6− anion is slightly distorted octahedral.
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Mizuno, O., M. Kumakura, A. Matsubara, and I. Yamamoto. "Inhibition of experimental allergic encephalomyelitis by MS-6044, a novel immunomodulating agent." International Journal of Immunopharmacology 10 (January 1988): 93. http://dx.doi.org/10.1016/0192-0561(88)90389-x.

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Valentini, V., C. Aristei, B. Glimelius, B. D. Minsky, K. Haustermans, H. J. Schmoll, D. Sebag-Montefiore, I. Taylor, E. van Cutsem, and C. Van de Velde. "6044 Multidisciplinary rectal cancer treatment: ‘Looking for an European Consensus’ (EURECA-CC2)." European Journal of Cancer Supplements 7, no. 2 (September 2009): 334–35. http://dx.doi.org/10.1016/s1359-6349(09)71139-5.

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Poirier, Jean-Paul. "CharlemagneJ. Favier Fayard, 1999 (769 pages). FF 180, hardback, ISBN 2 213 60404 5." European Review 8, no. 2 (May 2000): 269–71. http://dx.doi.org/10.1017/s1062798700004841.

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Fujita, Yoko, Ryo Murakami, Yasunori Muramatsu, Shunichi Miyakoshi, and Toshio Takatsu. "A-94964, Novel Inhibitor of Bacterial Translocase I, Produced by Streptomyces sp. SANK 60404." Journal of Antibiotics 61, no. 9 (September 2008): 545–49. http://dx.doi.org/10.1038/ja.2008.72.

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Hussein, Abdallah M., Mashhoor A. Al-Wardat, Ahmad Abushattal, Hatem S. Widyan, Enas M. Abu-Alrob, Oleg Malkov, and Martin A. Barstow. "Atmospheric and Fundamental Parameters of Eight Nearby Multiple Stars." Astronomical Journal 163, no. 4 (March 21, 2022): 182. http://dx.doi.org/10.3847/1538-3881/ac4fc7.

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Abstract We present the complete set of atmospheric and fundamental parameters, in addition to the masses, for the individual components of eight stellar systems. The list of the systems, whose orbital solutions were published recently, includes seven binaries (HIP 14524, HIP 16025, HIP 46199, HIP 47791, HIP 60444, HIP 61100, HIP 73085) and one triple system (HIP 28671). The systems were analyzed using a spectrophotometric computational technique known as Al-Wardats method for analyzing binary and multiple stellar systems, which makes use of ATLAS9 line-blanketed plane-parallel model atmospheres. Using these estimated parameters, the positions of the components were located on the Hertzsprung–Russell diagram, evolutionary tracks and isochrones to estimate their ages, the range depending on the uncertainties in their metallicities. Five systems were found to be pre-main-sequence stars (HIP 14524, HIP 46199, HIP 60444, HIP 61100, HIP 73085), two were main-sequence stars (the zero-age HIP 28671 and the 6.3 Gyr HIP 16025), and one is a subgiant system (HIP 47791) with an age of 1.4 Gyr. Fragmentation is proposed as the most probable formation process for the eight systems. A comparison between the estimated masses and the dynamical ones lead to new dynamical parallaxes for four systems: (28.63 ± 0.56) mas for HIP 14524, (15.6 ± 0.63) mas for HIP 16025, (9.73 ± 0.26) mas for HIP 47791, and (16.53 ± 0.59) mas for HIP 73085. Hence, the orbital solutions were reclassified. We conclude that Gaia DR3 parallaxes are more precise than those given by Gaia DR2 and Hipparcos 2.
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Torre-Bouscoulet, Luis, Óscar Arrieta-Rodriguez, Rogelio Pérez-Padilla, Abigail Guzmán-Barragán, Margarita Reyes-Zúñiga, David Martínez-Briseño, Rosario Fernández-Plata, and Cecilia García-Sancho. "Comorbilidades, calidad de sueño y calidad de vida en pacientes con cáncer pulmonar localmente avanzado." NCT Neumología y Cirugía de Tórax 74, no. 2 (2015): 87–94. http://dx.doi.org/10.35366/60414.

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Torre-Bouscoulet, Luis, Ranferi Ocaña-Guzmán, and Isabel Sada-Ovalle. "Humo de biomasa, inmunidad innata y Mycobacterium tuberculosis." NCT Neumología y Cirugía de Tórax 74, no. 2 (2015): 118–26. http://dx.doi.org/10.35366/60424.

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Fioriti, Vincenzo, Fabio Fratichini, Stefano Chiesa, and Claudio Moriconi. "Levy Foraging in a Dynamic Environment – Extending the Levy Search." International Journal of Advanced Robotic Systems 12, no. 7 (July 14, 2015): 98. http://dx.doi.org/10.5772/60414.

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Bogart, James P., and Michael W. Klemens. "Additional Distributional Records of Ambystoma Laterale, A. Jeffersonianum (Amphibia: Caudata) and Their Unisexual Kleptogens in Northeastern North America." American Museum Novitates 3627, no. 1 (2008): 1. http://dx.doi.org/10.1206/604.1.

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Anjanappa, Ravi B., Devang Mehta, M. N. Maruthi, Edward Kanju, Wilhelm Gruissem, and Hervé Vanderschuren. "Characterization of Brown Streak Virus–Resistant Cassava." Molecular Plant-Microbe Interactions® 29, no. 7 (July 2016): 527–34. http://dx.doi.org/10.1094/mpmi-01-16-0027-r.

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Cassava brown streak disease (CBSD) has become a major constraint to cassava production in East and Central Africa. The identification of new sources of CBSD resistance is essential to deploy CBSD mitigation strategies, as the disease is progressing westwards to new geographical areas. A stringent infection method based on top cleft–grafting combined with precise virus titer quantitation was utilized to screen 14 cassava cultivars and elite breeding lines. When inoculated with mixed infections of Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV), the scions of elite breeding lines KBH 2006/18 and KBH 2006/26 remained symptom-free during a 16-week period of virus graft inoculation, while susceptible varieties displayed typical CBSD infection symptoms at 4 weeks after grafting. The identified CBSD resistance was stable under the coinoculation of CBSV and UCBSV with cassava geminiviruses. Double-grafting experiments revealed that transmission of CBSV and UCBSV to CBSD-susceptible top scions was delayed when using intermediate scions of elite breeding lines KBH 2006/18 and KBH 2006/26. Nonetheless, comparison of virus systemic movement using scions from KBH2006/18 and a transgenic CBSD resistant 60444 line (60444-Hp9 line) showed that both CBSV and UCBSV move at undetectable levels through the stems. Further, protoplast-based assays of virus titers showed that the replication of CBSV is inhibited in the resistant line KBH2006/18, suggesting that the identified CBSD resistance is at least partially based on inhibition of virus replication. Our molecular characterization of CBSD resistance in cassava offers a robust virus-host system to further investigate the molecular determinants of CBSD resistance.
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Poirier, Jean-Paul. "Charlemagne. J. Favier. Fayard, 1999 (769 pages). FF 180, hardback, ISBN 2 213 60404 5." European Review 8, no. 2 (May 2000): 269–71. http://dx.doi.org/10.1017/s1062798700230251.

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Murakami, Ryo, Yoko Fujita, Masaaki Kizuka, Tomoka Kagawa, Yasunori Muramatsu, Shunichi Miyakoshi, Toshio Takatsu, and Masatoshi Inukai. "A-94964, a Novel Inhibitor of Bacterial Translocase I, Produced by Streptomyces sp. SANK 60404." Journal of Antibiotics 61, no. 9 (September 2008): 537–44. http://dx.doi.org/10.1038/ja.2008.71.

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Hertz, Daniel Louis, Chen Jiang, Kouros Owzar, Susan Halabi, William Kevin Kelly, Flora Mulkey, Jai Narendra Patel, et al. "A genome-wide association study (GWAS) of docetaxel-induced neutropenia in CALGB 90401/60404 (Alliance)." Journal of Clinical Oncology 32, no. 15_suppl (May 20, 2014): 9612. http://dx.doi.org/10.1200/jco.2014.32.15_suppl.9612.

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Lylova, E. S., A. V. Savinkova, E. M. Zhidkova, K. I. Kirsanov, M. G. Yakubovskaya, I. V. Budunova, and E. A. Lesovaya. "INHIBITION OF REDD1 EXPRESSION FOR THE REDUCTION OF GLUCOCORTICOID-INDUCED SIDE EFFECTS." Siberian journal of oncology 19, no. 6 (December 31, 2020): 73–81. http://dx.doi.org/10.21294/1814-4861-2020-19-6-73-81.

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Glucocorticoids (GC ) have been an integral component of the treatment of leukemias and lymphomas for several decades. Specific cytotoxic effect of GC on transformed lymphoblasts mediates their use at the stage of the remission induction as well as consolidation of treatment. However, the main problem of the long-term GC use is the development of atrophic and metabolic side effects as well as GC resistance. The biological effects of GC are realized via activation of the glucocorticoid receptor (GR) by two mechanisms: transrepression (TR) associated with the therapeutic effects of GC , and transactivation (TA ), which mediates the development of metabolic and atrophic complications. It was demonstrated that an increase in the expression of the GC - dependent gene REDD1 associated with GC -induced skin, muscle and bone atrophy of the skin, muscle and bone tissue was realized via the induction of transactivation. Therefore, identification of potential inhibitors of REDD1 expression and study of their biological effects in combination with GC in models of leukemia and lymphoma is of particular interest. In our recent study we have selected a number of drugs from the class of PI 3K/Akt/mTO R modulators using bioinformatic screening. These drugs effectively inhibited REDD1 expression, modulated GR activity and shifted it towards transrepression, and prevented the development of GC -induced side effects in mice. Here we aimed to study the effects of potential inhibitors of REDD1 expression from different pharmacological groups, the compounds Emetine and CGP -60474, on leukemia and lymphoma cells in combination with GC . We demonstrated antitumor effect of the compounds in vitro, a decrease in the expression of TA -associated genes and an increase in TR induction. Further studies of the antitumor effects of REDD1 expression inhibitors (Emetine and CGP -60474 is a promising area of research.
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Денисенко, Валерий, Valery Denisenko, Олег Якубайлик, and Oleg Yakubailik. "Taking account of topography when calculating the resistance of the global atmospheric conductor." Solnechno-Zemnaya Fizika 1, no. 1 (March 17, 2015): 104–8. http://dx.doi.org/10.12737/6044.

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The role of topography in the formation of the global electric circuit is analyzed. The topography of the Earth’s surface is determined using the GLOBE data-base providing data on height of the Earth’s surface above mean sea level in geodetic coordinates with spatial resolution of 30 angular seconds. The atmosphere is considered as a global conductor between the Earth’s surface and the ionosphere simulated as ideal conductors. Empirical models of air conductivity are used. To simplify the description of large-scale phenomena, the model is reduced to one-dimensional simulation of vertical columns of air. The inclusion of topography is shown to reduce the resistance of the atmosphere by 10 % and to reduce the local resistance above high mountains several times. Note that taking topography into account is also important in more general models of electrical conductivity of the atmosphere.
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KOLCUN, JOHN PAUL G., GEORGE M. GHOBRIAL, KENNETH M. CRANDALL, KEN HSUAN-KAN CHANG, GIACOMO PACCHIOROTTI, and MICHAEL Y. WANG. "Minimally Invasive Lumbar Interbody Fusion With an Expandable Meshed Allograft Containment Device: Analysis of Subsidence With 12-Month Minimum Follow-Up." International Journal of Spine Surgery 13, no. 4 (August 2019): 321–28. http://dx.doi.org/10.14444/6044.

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Luo, Saiyu, Xigun Yan, Qin Cui, Bin Xu, Huiying Xu, and Zhiping Cai. "Power scaling of blue-diode-pumped Pr:YLF lasers at 523.0, 604.1, 606.9, 639.4, 697.8 and 720.9 nm." Optics Communications 380 (December 2016): 357–60. http://dx.doi.org/10.1016/j.optcom.2016.06.026.

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Chen, Hui, Yu Lin Zhang, Ming Quan Shi, and Qing Hua Chen. "Numerical Simulation of Generator Air Duct Based on CFD Approach." Applied Mechanics and Materials 644-650 (September 2014): 678–83. http://dx.doi.org/10.4028/www.scientific.net/amm.644-650.678.

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Ventilation calculation is one of the important contents of generator design. Most researcher studies only on partial components or make important details simplified. They can’t accurately analyze the internal heat dissipation. In this paper the flow field was analyzed for a generator by CFD approach, using the package surface technology in order to keep the geometric characteristics. Based on the results of the analysis to improve its cooling duct. Before and after simulation results were contrasted, Cylinder head velocity distribution increases from 0.1-0.2m/s to 1-4m/s, Silencer, motor and cylinder head average heat transfer coefficient increased respectively by 78.2%, 116.4% and 604.7%, Flux on outlet1 is increased by 13.8%, The improved model cooling effect was significantly higher than the pre model. Research on the generator duct design has important reference value.
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KNUTSON, KATHLEEN M., ELMER H. MARTH, and MARY K. WAGNER. "Use of Microwave Ovens to Pasteurize Milk." Journal of Food Protection 51, no. 9 (September 1, 1988): 715–19. http://dx.doi.org/10.4315/0362-028x-51.9.715.

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High-temperature short-time (HTST) and low-temperature long-time (LTLT) pasteurization were simulated using uninoculated and inoculated milks that were heated in microwave ovens. Heating milk (76 ml) for 59 s at 700 W achieved a temperature of 71.7°C, but heating for 60–65 s and holding for 15 s failed to inactivate all added cells of Salmonella typhimurium, Escherichia coli or Pseudomonas fluorescens. Milk, 453.6 g (ca. one-half quart) or 604.8 g (ca. two-thirds quart), was heated to &gt;62.8°C, but &lt;71.7°C, in 4.5 to 5 min, depending on power (550 or 700 W) that was used, and refrigerated overnight. Such treatments failed to reduce the population of Streptococcus faecalis in the milks by the degree that occurred when inoculated milk was heated in a water bath at 62.8°C for 30 min.
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Dat Mai, Ngoc Xuan, Tan Le-Hoang Doan, Le Nguyen Bao Thu, and Bach Thang Phan. "EvaluationofremovalefficiencyofFe(III)andAl(III)ionsinacidsulfate waterusing agarose-basedmagnesiumoxidecomposite." Ministry of Science and Technology, Vietnam 63, no. 3 (September 21, 2021): 30–34. http://dx.doi.org/10.31276/vjste.63(3).30-34.

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Agarose/MgO composite adsorbents were developed through interspersing MgO nanoparticles with agarose to create an absorbent. The elimination capacity of the composite towards iron (Fe), aluminium (Al), and arsenate (As) in acid sulfate water was evaluated by means of batch method at room temperature. The constituents of the composite were characterized by thermal gravimetric analysis (TGA). The removal efficiency was determined through inductively coupled plasma (ICP) mass spectrometry. The composite adsorbent exhibited an excellent adsorption capacity towards three types of ions and heavy metals that are found in acid sulfate water. After treating with agarose/MgO, the concentrations of Fe and Al decreased from 60.28 and 604.84 μg/l, respectively, to under 3.42 and 1.78 μg/l, respectively. These exceptional results reveal the potential uses of agarose/MgO composites as adsorbents in the treatment of acid sulfate water.
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Heller, A. R., R. J. Litz, D. Wiener, C. Dammann, S. Weigel, J. Neidel, M. P. Wirth, and T. Koch. "Impact of thoracic epidural analgesia on revenue using G-DRG M01B, OPS-301 5-604.0 (radical retropubic prostatectomy)." European Journal of Anaesthesiology 22, Supplement 34 (May 2005): 114. http://dx.doi.org/10.1097/00003643-200505001-00406.

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38

Jang, Eun-Suk, and Chun-Won Kang. "Delignification Effects on Indonesian Momala (Homalium foetidum) and Korean Red Toon (Toona sinensis) Hardwood Pore Structure and Sound Absorption Capabilities." Materials 14, no. 18 (September 10, 2021): 5215. http://dx.doi.org/10.3390/ma14185215.

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Among the various methods used to improve the sound absorption capability of wood, we focused on delignification in Indonesian momala (Homalium foetidum) and Korean red toon (Toona sinensis). We performed gas permeability, pore size, and porosity analyses and evaluated how the change in the pore structure affects the sound absorption capabilities. Results show that delignification increased the through-pore porosity and improved sound absorption capability in both species. In addition, the air gap in the rear space maximized the sound absorption of momala and the red toon. The noise reduction coefficient (NRC) of delignified momala (90 min) with a 3 cm air gap was 0.359 ± 0.023. This is approximately 154.6% higher than that of untreated momala without an air gap. The NRC of delignificated red toon (90 min) with a 3 cm air gap was 0.324 ± 0.040, an increase of 604.3% over untreated red toon without an air gap.
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Standley, Laurel J., Ruthann A. Rudel, Christopher H. Swartz, Kathleen R. Attfield, Jeff Christian, Mike Erickson, and Julia G. Brody. "Wastewater‐contaminated groundwater as a source of endogenous hormones and pharmaceuticals to surface water ecosystems." Environmental Toxicology and Chemistry 27, no. 12 (December 2008): 2457–68. http://dx.doi.org/10.1897/07-604.1.

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40

Sinnett, Danielle E., Mark E. Hodson, and Tony R. Hutchings. "FOOD-CHAIN TRANSFER OF CADMIUM AND ZINC FROM CONTAMINATED URTICA DIOICA TO HELIX ASPERSA AND LUMBRICUS TERRESTRIS." Environmental Toxicology and Chemistry 28, no. 8 (2009): 1756. http://dx.doi.org/10.1897/08-604.1.

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41

Mulari, Heta. "Tyttöjä rajoilla. Transnationaalisuus ja seksuaalisuus elokuvissa Lilja 4-ever ja Sano että rakastat mua." Lähikuva – audiovisuaalisen kulttuurin tieteellinen julkaisu 29, no. 4 (January 17, 2017): 27–44. http://dx.doi.org/10.23994/lk.60474.

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Tyttöjä rajoilla. Transnationaalisuus ja seksuaalisuus elokuvissa Lilja 4-ever ja Sano että rakastat muaArtikkelissa tarkastellaan tyttöyttä, transnationaalisuutta ja seksuaalisuutta ruotsalaisissa tyttöelokuvissa Lilja 4-ever ja Sano että rakastat mua. Huomio kohdistuu siihen, kuinka elokuvissa määritellään melodraaman keinoin itäeurooppalaista tyttöyttä sekä urbaania, monikulttuurista nuorisokulttuuria suhteessa niin sanottuun ruotsalaiseen tasa-arvotyttöyteen.Artikkelissa esitetään, että molemmissa elokuvissa tyttöys – sekä etnisesti ruotsalainen että maahanmuuttajatyttöys – nostetaan esiin yhteiskunnallisen muutoksen symbolina sekä ja kansallisvaltion uusia kohtaamisia ilmentäen.Girls on the Frontier. Transnationalism and Sexuality in Lilya 4-ever and Say that You Love MeThis article discusses girlhood, transnationalism and sexuality in Swedish films Lilya 4-ever and Say that You Love Me. The article focuses on how these films imagine Eastern European girlhood, as well as urban, multicultural youth culture in relation to Swedish gender egalitarian girlhood.The films can be defined as youth melodramas: films that combine conventions from youth film and melodrama. The article suggests that in both of these films ethnically Swedish and immigrant girlhood is foregrounded as symbols of social change and new encounters in the Swedish nation state.
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Archambault, Amy, Thomas W. Major, Jason P. Carey, Giseon Heo, Hisham Badawi, and Paul W. Major. "A comparison of torque expression between stainless steel, titanium molybdenum alloy, and copper nickel titanium wires in metallic self-ligating brackets." Angle Orthodontist 80, no. 5 (September 2010): 884–89. http://dx.doi.org/10.2319/102809-604.1.

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43

Uysal, Tancan, Ayca Ustdal, Mehmet Fatih Sonmez, and Figen Ozturk. "Stimulation of Bone Formation by Dietary Boron in an Orthopedically Expanded Suture in Rabbits." Angle Orthodontist 79, no. 5 (September 1, 2009): 984–90. http://dx.doi.org/10.2319/112708-604.1.

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Abstract Objective: To evaluate the effects of dietary boron on bone regeneration in rabbits in response to expansion of the midpalatal suture during different retention periods. Materials and Methods: Twenty-eight 12-week-old New Zealand white male rabbits were separated into four equal groups: group 1 (B+10) and group 2 (B−10) had retention periods of 10 days with or without boron intake, respectively. Group 3 (B+20, with boron) and group 4 (B−20, without boron) were retained for 20 days. All groups had a 5-day expansion period. For both B+ groups, boron was prepared in distilled water and given to the rabbits during their (1) nursery phase (40 days), (2) expansion phase, and (3) retention period at a dosage of 3 mg/kg daily by oral gavage. Bone regeneration in the midpalatal suture was evaluated by a bone histomorphometric method, and the mineralized area (Md.Ar), fibrosis area (Fb.Ar), mineralized area/fibrosis area (Md.Ar/Fb.Ar), bone area (B.Ar) and osteoblast number (N.Ob) parameters were evaluated. Results: Statistical analysis showed significant differences between groups for all investigated measurements. Md.Ar (P &lt; .01), Md.Ar/Fb.Ar (P &lt; .001), B.Ar (P &lt; .01), and N.Ob (P &lt; .01) parameters were increased and Fb.Ar (P &lt; .01) was decreased in groups B+10 and B+20. No significant differences were observed during an additional 10-day retention period in all groups (P &lt; .05). Conclusions: Boron has a positive effect on the early phase of bone regeneration of the midpalatal suture in response to expansion and may be beneficial in routine maxillary expansion procedures.
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Kitahara, Toru, Akihiko Nakasima, Shinichi Kurahara, and Yuji Shiratsuchi. "Hard and Soft Tissue Stability of Orthognathic Surgery." Angle Orthodontist 79, no. 1 (January 1, 2009): 158–65. http://dx.doi.org/10.2319/122707-604.1.

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Abstract Objective: To test the hypothesis that there is no difference in the stability of the hard and soft tissue changes following a surgical mandibular setback using a sagittal split ramus osteotomy or an intraoral vertical ramus osteotomy. Materials and Methods: The samples consisted of 45 female patients with mandibular prognathism, who were divided into two groups. Twenty-three underwent a sagittal split ramus osteotomy (SSRO) with rigid fixation by titanium mini-screws and maxillomandibular fixation (MMF) for 14.0 ± 0.7 days. Twenty-two underwent intraoral vertical ramus osteotomy (IVRO) without rigid fixation, and MMF was released 21.5 ± 3.3 days after surgery. Data were collected from standardized cephalometric radiographs taken at the start of preoperative orthodontic treatment (T1), immediately after surgery (MMF, T2), and the completion of postoperative treatment (T3). Angular measurements were compared on each of T1, T2, and T3. Results: There were no significant differences in the pretreatment hard and soft tissue morphology between the SSRO and IVRO. However, when fixation was released, the mandible was posteriorly positioned in the IVRO group. In the soft tissue profile, the mental region was located backward in the IVRO group at postoperative stage (T3). Conclusions: The hypothesis is rejected. The soft tissue profile of the IVRO group especially showed a retromandibular position after postoperative treatment in comparison with the SSRO group. This tendency of the IVRO group would contribute to the database for treatment planning and prediction.
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Szczykowska, Joanna, Anna Siemieniuk, and Józefa Wiater. "DIVERSITY OF THE TSI INDICATORS OF THE MIDDLE-FOREST SMALL RETENTION RESERVOIR." Journal of Ecological Engineering 16 (2015): 54–61. http://dx.doi.org/10.12911/22998993/60454.

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46

Dębska, Anna, Krzysztof Jóźwiakowski, Magdalena Gizińska-Górna, Aneta Pytka, Michał Marzec, Bożena Sosnowska, and Agata Pieńko. "THE EFFICIENCY OF POLLUTION REMOVAL FROM DOMESTIC WASTEWATER IN CONSTRUCTED WETLAND SYSTEMS WITH VERTICAL FLOW WITH COMMON REED AND GLYCERIA MAXIMA." Journal of Ecological Engineering 16 (2015): 110–18. http://dx.doi.org/10.12911/22998993/60464.

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47

Bogdał, Andrzej, and Tomasz Kowalik. "VARIABILITY OF VALUES OF PHYSICOCHEMICAL WATER QUALITY INDICES ALONG THE LENGTH OF THE IWONICZANKA STREAM." Journal of Ecological Engineering 16 (2015): 168–75. http://dx.doi.org/10.12911/22998993/60474.

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48

WATANABE, Hikaru, Rohko TAKAKURA-YAMAMOTO, Mayumi KUROSE, Kenshi YOSHIDA, Kazuyuki OKU, Ikuo SAWATANI, Tomoyuki NISHIMOTO, Michio KUBOTA, Hiroto CHAEN, and Shigeharu FUKUDA. "Production of Isocyclomaltopentaose from Starch Using Isocyclomaltooligosaccharide Glucanotransferase." Bioscience, Biotechnology, and Biochemistry 70, no. 12 (December 23, 2006): 3013–18. http://dx.doi.org/10.1271/bbb.60404.

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49

ADACHI, Osao, Yoshitaka ANO, Hirohide TOYAMA, and Kazunobu MATSUSHITA. "Enzymatic Preparation of Metabolic Intermediates, 3-Dehydroquinate and 3-Dehydroshikimate, in the Shikimate Pathway." Bioscience, Biotechnology, and Biochemistry 70, no. 12 (December 23, 2006): 3081–83. http://dx.doi.org/10.1271/bbb.60414.

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50

YAMAKOSHI, Jun, Satoshi FUKUDA, Takuya SATOH, Ryouhei TSUJI, Makoto SAITO, Akio OBATA, Asahi MATSUYAMA, Mamoru KIKUCHI, and Terukazu KAWASAKI. "Antihypertensive and Natriuretic Effects of Less-Sodium Soy Sauce Containing γ-Aminobutyric Acid in Spontaneously Hypertensive Rats." Bioscience, Biotechnology, and Biochemistry 71, no. 1 (January 23, 2007): 165–73. http://dx.doi.org/10.1271/bbb.60424.

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