Journal articles: '46L55'

1

Farsi, Carla. "SOFT C*-ALGEBRAS." Proceedings of the Edinburgh Mathematical Society 45, no. 1 (February 2002): 59–65. http://dx.doi.org/10.1017/s0013091500000547.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractIn this paper we consider soft group and crossed product $C^*$-algebras. In particular we show that soft crossed product $C^*$-algebras are isomorphic to classical crossed product $C^*$-algebras. We also prove that large classes of soft $C^*$-algebras have stable rank equal to infinity.AMS 2000 Mathematics subject classification: Primary 46L80; 46L55

2

Deicke, Klaus. "THE CROSSED PRODUCT BY A POINTWISE UNITARY ACTION ON A C*-ALGEBRA WITH CONTINUOUS TRACE." Proceedings of the Edinburgh Mathematical Society 44, no. 1 (February 2001): 215–18. http://dx.doi.org/10.1017/s0013091500000195.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractLet $G$ be a locally compact group, $A$ a continuous trace $C^*$-algebra, and $\alpha$ a pointwise unitary action of $G$ on $A$. It is a result of Olesen and Raeburn that if $A$ is separable and $G$ is second countable, then the crossed product $A\times_\alpha G$ has continuous trace. We present a new and much more elementary proof of this fact. Moreover, we do not even need the separability assumptions made on $A$ and $G$.AMS 2000 Mathematics subject classification: Primary 46L55

3

ㅤ. "Vos / Vos (TvAR 1993/4655)." Tijdschrift voor Agrarisch Recht 53, no. 11 (November 1, 1993): ㅤ. http://dx.doi.org/10.5117/tvar1993.11.008.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Kretschmer, A. E., R. M. Sonoda, R. C. Bullock, and T. C. Wilson. "Registration of IRFL 4655 Macroptilium Atropurpureum Germplasm." Crop Science 32, no. 3 (May 1992): 836. http://dx.doi.org/10.2135/cropsci1992.0011183x003200030066x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Harapan Parlindungan Ringoringo, Jun Rahmawati Surya Mentari, Roselina Panghiyangani, Edi Hartoyo, and Rahmiati Lao. "Hematological profile of children under five years with typhoid fever at Idaman Banjarbaru Hospital, Indonesia." Bali Medical Journal 11, no. 2 (July 30, 2022): 775–78. http://dx.doi.org/10.15562/bmj.v11i2.2669.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Introduction: Typhoid fever is a disease caused by Salmonella typhi, Salmonella paratyphi A, B, C. An estimated 200,000 people die each year from about 21.6 million people infected with typhoid fever. This study aims to determine the hematological profile in typhoid fever cases in children under five at Idaman Banjarbaru Hospital. Methods: The research was carried out with a retrospective descriptive approach with a consecutive sampling technique. The research subjects were children under five diagnosed with typhoid fever recorded in the Idaman Banjarbaru Hospital's medical records for July 2018 to January 2019. Results: The sample consisted of 58 patients, 32 boys, and 26 girls. Most patients were found in 12 - <36 months, namely 28 (48.28%) children. Thirty-eight (65.52%) children have a normal weight. The hematological profile showed that 46.55% of the patients had iron deficiency anemia (IDA). Hematocrit levels decreased in 51.72% of patients. Erythrocyte levels in 86.21% of patients were normal. Low MCV, low MCH, IDA were found in 46.55%, 36.21%, 46.55% of patients. Leukopenia was present in 17.24% of children. All patients had normal basophil values. Eosinopenia, band neutropenia, segmented neutropenia, lymphocytosis, monocytosis were found in 69.09%, 90.90%, 56.37%, 58.18%, 58.18% of children, respectively. Thrombocytopenia and thrombocytosis were found in the same percentage, 13.80%. Conclusion: The haematological profile of typhoid fever patients in children under five can have different results depending on each child's body's response to S. typhi and S. paratyphi that enter the body.

6

González, N. Castro, J. J. Koliha, and Yimin Wei. "ON INTEGRAL REPRESENTATIONS OF THE DRAZIN INVERSE IN BANACH ALGEBRAS." Proceedings of the Edinburgh Mathematical Society 45, no. 2 (June 2002): 327–31. http://dx.doi.org/10.1017/s0013091500000523.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractThe purpose of this paper is to derive an integral representation of the Drazin inverse of an element of a Banach algebra in a more general situation than previously obtained by the second author, and to give an application to the Moore–Penrose inverse in a $C^*$-algebra.AMS 2000 Mathematics subject classification:Primary 46H05; 46L05

7

Kumar, Ajay. "INVOLUTION AND THE HAAGERUP TENSOR PRODUCT." Proceedings of the Edinburgh Mathematical Society 44, no. 2 (June 2001): 317–22. http://dx.doi.org/10.1017/s0013091599000772.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractWe show that the involution $\theta(a\otimes b)=a^*\otimes b^*$ on the Haagerup tensor product $A\otimes_{\mrm{H}}B$ of $C^*$-algebras $A$ and $B$ is an isometry if and only if $A$ and $B$ are commutative. The involutive Banach algebra $A\otimes_{\mrm{H}}A$ arising from the involution $a\otimes b\to b^*\otimes a^*$ is also studied.AMS 2000 Mathematics subject classification: Primary 46L05; 46M05

8

Deussen, Heinz-Josef, Lone Jeppesen, Norbert Schärer, Finn Junager, Bjørn Bentzen, Beat Weber, Volker Weil, Sandor Josef Mozer, and Per Sauerberg. "Process Development and Scale-Up of the PPAR Agonist NNC 61-4655." Organic Process Research & Development 8, no. 3 (May 2004): 363–71. http://dx.doi.org/10.1021/op034048j.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Raeburn, Iain, Aidan Sims, and Trent Yeend. "HIGHER-RANK GRAPHS AND THEIR $C^*$-ALGEBRAS." Proceedings of the Edinburgh Mathematical Society 46, no. 1 (January 27, 2003): 99–115. http://dx.doi.org/10.1017/s0013091501000645.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractWe consider the higher-rank graphs introduced by Kumjian and Pask as models for higher-rank Cuntz–Krieger algebras. We describe a variant of the Cuntz–Krieger relations which applies to graphs with sources, and describe a local convexity condition which characterizes the higher-rank graphs that admit a non-trivial Cuntz–Krieger family. We then prove versions of the uniqueness theorems and classifications of ideals for the $C^*$-algebras generated by Cuntz–Krieger families.AMS 2000 Mathematics subject classification: Primary 46L05

10

Kribs, David W. "QUANTUM CHANNELS, WAVELETS, DILATIONS AND REPRESENTATIONS OF $\mathcal{O}_{n}$." Proceedings of the Edinburgh Mathematical Society 46, no. 2 (June 2003): 421–33. http://dx.doi.org/10.1017/s0013091501000980.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractWe show that the representations of the Cuntz $C^*$-algebras $\mathcal{O}_n$ which arise in wavelet analysis and dilation theory can be classified through a simple analysis of completely positive maps on finite-dimensional space. Based on this analysis, we find an application in quantum information theory; namely, a structure theorem for the fixed-point set of a unital quantum channel. We also include some open problems motivated by this work.AMS 2000 Mathematics subject classification: Primary 46L45; 47A20; 46L60; 42C40; 81P15

11

Ozawa, Narutaka. "A NON-EXTENDABLE BOUNDED LINEAR MAP BETWEEN C*-ALGEBRAS." Proceedings of the Edinburgh Mathematical Society 44, no. 2 (June 2001): 241–48. http://dx.doi.org/10.1017/s0013091599000978.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractWe present an example of a $C^*$-subalgebra $A$ of $\mathbb{B}(H)$ and a bounded linear map from $A$ to $\mathbb{B}(K)$ which does not admit any bounded linear extension. This generalizes the result of Robertson and gives the answer to a problem raised by Pisier. Using the same idea, we compute the exactness constants of some Q-spaces. This solves a problem raised by Oikhberg. We also construct a Q-space which is not locally reflexive.AMS 2000 Mathematics subject classification: Primary 46L05. Secondary 46L07

12

Kodaka, Kazunori. "C*-ALGEBRAS THAT ARE ISOMORPHIC AFTER TENSORING AND FULL PROJECTIONS." Proceedings of the Edinburgh Mathematical Society 47, no. 3 (October 2004): 659–68. http://dx.doi.org/10.1017/s001309150200024x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractLet $A$ be a unital $C^*$-algebra and for each $n\in\mathbb{N}$ let $M_n$ be the $n\times n$ matrix algebra over $\mathbb{C}$. In this paper we shall give a necessary and sufficient condition that there is a unital $C^*$-algebra $B$ satisfying $A\not\cong B$ but for which $A\otimes M_n\cong B\otimes M_n$ for some $n\in\mathbb{N}\setminus\{1\}$. Also, we shall give some examples of unital $C^*$-algebras satisfying the above property.AMS 2000 Mathematics subject classification: Primary 46L05

13

Paulsen, Vern I., and Roger R. Smith. "DIAGONALS IN TENSOR PRODUCTS OF OPERATOR ALGEBRAS." Proceedings of the Edinburgh Mathematical Society 45, no. 3 (October 2002): 647–52. http://dx.doi.org/10.1017/s0013091500001073.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractIn this paper we give a short, direct proof, using only properties of the Haagerup tensor product, that if an operator algebra $A$ possesses a diagonal in the Haagerup tensor product of $A$ with itself, then $A$ must be isomorphic to a finite-dimensional $C^*$-algebra. Consequently, for operator algebras, the first Hochschild cohomology group $H^1(A,X)=0$ for every bounded, Banach $A$-bimodule $X$, if and only if $A$ is isomorphic to a finite-dimensional $C^*$-algebra.AMS 2000 Mathematics subject classification: Primary 46L06. Secondary 46L05

14

Murakami, Hideki, Norio Kawahara, Satoru Demura, and Katsuro Tomita. "4:46155. Surgical strategy for spinal metastasis of lung cancer: indication of total en bloc spondylectomy." Spine Journal 5, no. 4 (July 2005): S81. http://dx.doi.org/10.1016/j.spinee.2005.05.158.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Cheon, Chan Sup Shim;Young Koog, Jong Ho Moon;Young Deok Cho, and Moon Sung Lee. "4655 Preliminary results of the new membrane covered self-expandable nitinol biliary metal stent." Gastrointestinal Endoscopy 51, no. 4 (April 2000): AB194. http://dx.doi.org/10.1016/s0016-5107(00)14502-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Dykema, Kenneth J., and Dimitri Shlyakhtenko. "EXACTNESS OF CUNTZ–PIMSNER C*-ALGEBRAS." Proceedings of the Edinburgh Mathematical Society 44, no. 2 (June 2001): 425–44. http://dx.doi.org/10.1017/s001309159900125x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractLet $H$ be a full Hilbert bimodule over a $C^*$-algebra $A$. We show that the Cuntz–Pimsner algebra associated to $H$ is exact if and only if $A$ is exact. Using this result, we give alternative proofs for exactness of reduced amalgamated free products of exact $C^*$-algebras. In the case in which $A$ is a finite-dimensional $C^*$-algebra, we also show that the Brown–Voiculescu topological entropy of Bogljubov automorphisms of the Cuntz–Pimsner algebra associated to an $A,A$ Hilbert bimodule is zero.AMS 2000 Mathematics subject classification: Primary 46L08. Secondary 46L09; 46L54

17

Baaj, Saad, and Stefaan Vaes. "DOUBLE CROSSED PRODUCTS OF LOCALLY COMPACT QUANTUM GROUPS." Journal of the Institute of Mathematics of Jussieu 4, no. 1 (January 2005): 135–73. http://dx.doi.org/10.1017/s1474748005000034.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

For a matched pair of locally compact quantum groups, we construct the double crossed product as a locally compact quantum group. This construction generalizes Drinfeld’s quantum double construction. We study the modular theory and the $\mathrm{C}^*$-algebraic properties of these double crossed products, as well as several links between double crossed products and bicrossed products. In an appendix, we study the Radon–Nikodym derivative of a weight under a quantum group action (following Yamanouchi) and obtain, as a corollary, a new characterization of closed quantum subgroups. AMS 2000 Mathematics subject classification: Primary 46L89. Secondary 46L65

18

Bori, Haoua, Harouna Ambouta Karimou, Iro Guimbo Dan, and Toudou Adam. "Production foliaire de <i>Senna obtusifolia</i> (L.) Irwin & Barneby en culture irriguée dans le Sahel nigérien, Niger." International Journal of Biological and Chemical Sciences 17, no. 4 (September 19, 2023): 1486–96. http://dx.doi.org/10.4314/ijbcs.v17i4.16.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Longtemps considérée au Niger, comme une rudérale mais aussi un adventice des cultures, Senna obtusifolia est désormais une espèce utile, conservée délibérément dans les champs en saison des pluies. Elle est utilisée en alimentation animale et encore plus en alimentation humaine, et génère des revenus substantiels aux populations vulnérables surtout en zones rurales. La présente étude conduite sur la parcelle expérimentale de la Faculté d’Agronomie de l’Université Abdou Moumouni de Niamey avait pour objectif d’étudier les possibilités de la culture de Senna obtusifolia pendant la période sèche de l’année. Le dispositif expérimental utilisé était composé de 16 parcelles de 6 m2 dont 8 exploitées et 8 autres non exploitées considérées comme des témoins. Les semences utilisées ont été récoltées en fin septembre 2020. La levée des plantules a été observée à partir du 4 e jour après semis (75%). Elle a été poursuivie jusqu’à 8 jours où toutes les graines viables ont germé (96%). La hauteur des plants la plus élevée a été enregistrée au niveau des parcelles témoin avec l’écartement de 30 cm (46,55±7,16 cm) suivi des parcelles témoin de l’écartement de 20 cm (42,75±4,68cm). Dans ces parcelles, les plants de S. obtusifolia avaient atteint la sénescence avant ceux des parcelles exploitées. Les taux de floraison des plants des parcelles exploitées (72,00±6 et 68,00±7) étaient supérieurs à ceux des parcelles qui n’ont pas fait l’objet d’exploitation (48,00±4 et 50,00±5). A chaque récolte, la production foliaire était significativement différente entre les parcelles exploitées. La production totale était de 1304,20 et 745,70 kg/ha respectivement pour les parcelles d’écartement de 20 cm et 30 cm. Long time considered in Niger as a ruderal but also a weed of crops, Senna obtusifolia is now a useful species, deliberately kept in fields during the rainy season. It is used in animal feed and even more in human food, and has generated substantial income for vulnerable populations, especially in rural areas. The present study conducted on the experimental plot of the Faculty of Agronomy of the Abdou Moumouni University of Niamey aimed to study the possibilities of growing Senna obtusifolia during the dry period of the year. The experimental device was used composed of 16 plots of 6 m2 including 8 exploited and 8 others not exploited as controls. The seeds used were observed at the end of September 2020. Seedling emergence was observed from the 4th day after sowing (75%). It was continued until 8 days when all viable seeds germinated (96%). The highest plant height was recorded at the level of the control plots with the spacing of 30 cm (46.55 ± 7.16 cm) followed by the control plots with the spacing of 20 cm (42.75 ± 4. 68cm). In these plots, the plants of S. obtusifolia had reached senescence before those of the exploited plots. The flowering rates of the plants in the exploited plots (72.00±6 and 68.00±7) were higher than those of the plots that were not exploited (48.00±4 and 50.00± 5). At each harvest, foliar production was significantly different between the exploited plots. The total production was 1304.20 and 745.70 kg/ha respectively for the 20 cm and 30 cm spacing plots

19

Zhou, B., and D. Luo. "734 Exosome-mediated miR-4655-3p contributes to UV-radiation induced bystander effects by targeting E2F2." Journal of Investigative Dermatology 139, no. 5 (May 2019): S127. http://dx.doi.org/10.1016/j.jid.2019.03.810.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Chen, Y., B. Zhou, and D. Luo. "744 Exosome-mediated miR-4655-3p contributes to UV-radiation induced bystander effects by targeting E2F2." Journal of Investigative Dermatology 139, no. 5 (May 2019): S128. http://dx.doi.org/10.1016/j.jid.2019.03.820.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Chen, Xian, Li Wang, Hui Yu, Qi Shen, Yu Hou, Yao-Xiong Xia, Lan Li, Li Chang, and Wen-Hui Li. "Irradiated lung cancer cell-derived exosomes modulate macrophage polarization by inhibiting MID1 via miR-4655-5p." Molecular Immunology 155 (March 2023): 58–68. http://dx.doi.org/10.1016/j.molimm.2023.01.009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Shanley, Jack, Danny Michael, and Patrick Senft. "Book Reviews." Armax: The Journal of Contemporary Arms VII, no. 1 (2021): 97–102. http://dx.doi.org/10.52357/armax02539.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

A History of the Small Arms Made by the Sterling Armament Company: Excellence in Adversity Reviewed by: Jack Shanley Peter Laidler, James Edmiston & David Howroyd. Barnsley: Pen & Sword, 2020. ISBN 978-15-26773-30-2. xv + 352 pp., 32 col. illus., 350 b. & w. illus. £40. Winchester Model 1895: Last of the Classic Lever Actions Reviewed by: Danny Michael Rob Kassab & Brad Dunbar. Boca Raton: Buffalo Cove Publishing, 2019. ISBN 978-0-578-46655-2. 432 pp., numerous col. illus. $89.99. Firearms of the Texas Rangers: From the Frontier Era to the Modern Age Reviewed by: Patrick Senft Doug Dukes. Denton: University of North Texas Press, 2020. ISBN 978-1-574-41810-1. 640 pp., 182 b. & w. illus. $45.

23

Xue, Yifeng. "Classification of the crossed product C(m) × θZp for certain pairs (M, θ)." Filomat 24, no. 2 (2010): 131–42. http://dx.doi.org/10.2298/fil1002131x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Let M be a separable compact Hausdorff space with dim M ? 2 and ? : M ? M be a homeomorphism with prime period p (p ? 2). Set M? = {x ( M|?(x) = x} = ( and M0 = M\M? . Suppose that M0 is dense in M and H2(M0/?, Z) ( 0, H2(?(M0/?), Z) ( 0. Let M' be another separable compact Hausdorff space with dim M' ? 2 and ?' be the self-homeomorphism of M' with prime period p. Suppose that M'0 = M'\M'?' is dense in M'. Then C(M) ? ?Zp ( C(M') ? ?'Zp if there is a homeomorphism F from M/? onto M'/?' such that F(M?) = M'?'. Thus, if (M, ?) and (M', ?') are orbit equivalent, then C(M) ? ?Zp ( C(M') ? ?'Zp. 2010 Mathematics Subject Classifications. 46L05. .

24

Perkins, Chris. "Book review: Crampton, J.W. and Elden, S., editors 2007: Space, knowledge and power: Foucault and geography. Aldershot: Ashgate. 377 pp. £60 cloth, £22.50 paper. ISBN: 978 0 7546 4655 6 cloth, 978 0 7546 4655 6 paper." Progress in Human Geography 33, no. 3 (May 26, 2009): 425–28. http://dx.doi.org/10.1177/03091325090330031602.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Timoney, Richard M. "AN INTERNAL CHARACTERIZATION OF COMPLETE POSITIVITY FOR ELEMENTARY OPERATORS." Proceedings of the Edinburgh Mathematical Society 45, no. 2 (June 2002): 285–300. http://dx.doi.org/10.1017/s0013091500000687.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

AbstractComplete positivity of ‘atomically extensible’ bounded linear operators between $C^*$-algebras is characterized in terms of positivity of a bilinear form on certain finite-rank operators. In the case of an elementary operator on a $C^*$-algebra, the approach leads us to characterize k-positivity of the operator in terms of positivity of a quadratic form on a subset of the dual space of the algebra and in terms of a certain inequality involving factorial states of finite type I.As an application we characterize those $C^*$-algebras where every k-positive elementary operator on the algebra is completely positive. They are either k-subhomogeneous or k-subhomogeneous by antiliminal. We also give a dual approach to the metric operator space introduced by Arveson.AMS 2000 Mathematics subject classification: Primary 46L05. Secondary 47B47; 47B65

26

Gutekunst, Kevin R., and Richard J. Cruise. "Human Factors Simulation to Support Software Design." Proceedings of the Human Factors Society Annual Meeting 31, no. 12 (September 1987): 1416–20. http://dx.doi.org/10.1177/154193128703101225.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Computer simulation of the operator/system interface is a useful tool for supporting system software design. Simulation is also a flexible and cost effective method for applying human engineering analysis techniques as required by MIL-H-46855 (Human Engineering Requirements for Military Systems, Equipment and Facilities). This paper describes the integrated methodology used to model the operator/computer interaction for a newly developed military system. The operator/computer interface was potentially complex since the operators were required to control several sensors as well as communicate intelligence information within specified time constraints. In order to focus the design process and optimize the operator/computer interface, a computer simulation using the Micro SAINT software package was performed. This simulation provided a dynamic and integrated approach for performing subsequent design trade offs and developing software interface specifications and requirements.

27

Chadwick, Andrew J. "Risk and Reliability: Coastal and Hydraulic Engineering ReeveDominic Abingdon, UKTaylor & Francis, 2009, 978-0-415-46755-1, £60.00, 302." Proceedings of the Institution of Civil Engineers - Maritime Engineering 165, no. 1 (March 2012): 41. http://dx.doi.org/10.1680/maen.2012.165.1.41.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Johansen, Steen K., and Lars Martiny. "Synthesis of tritium and carbon-14 labelled NNC 61-4655: a potent dual-acting PPAR? and PPAR? agonist." Journal of Labelled Compounds and Radiopharmaceuticals 46, no. 9 (2003): 861–71. http://dx.doi.org/10.1002/jlcr.725.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Zhang, Baoyuan, Zhixiang Zhang, Jiaming Gao, Shiqiang Lu, Ran Pang, Dongfang Li, Xun Huang, Natasha Qin, Leo Liu, and Zaiqi Wang. "Abstract 4655: Targeting FAK improves the tumor penetration of antibody-drug conjugates to strengthen the anti-cancer responses." Cancer Research 84, no. 6_Supplement (March 22, 2024): 4655. http://dx.doi.org/10.1158/1538-7445.am2024-4655.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Abstract Antibody-drug conjugates (ADCs) such as HER2 ADC Enhertu and TROP2 ADC Trodelvy have been proved to be the promising therapeutic agents in portion of cancer diseases. However, there are still numerous patients refractory to the therapy, indicating that the efficacy of ADCs may need to be further optimized. Here, we report that the excessive cancer-associated fibroblasts (CAFs) can serve as a fibrotic barrier, to the detriment of anti-tumor effects from ADCs by alleviating their tissue penetration. Mechanistically, the cancer cells can transform the normal fibrotic cells into CAFs which are featured by the hyperactivated focal adhesion kinase (FAK) signaling. The fast-growing CAFs would decrease the tumor uptake of the big molecules, conferring drug resistance of ADCs to the cancer cells. Targeting FAK with a small molecule inhibitor IN10018 is capable to reduce CAFs associated tumor barrier, elevating the tissue penetration of different types of ADCs regardless their respective targets. The combination regimen comprising IN10018 and the ADCs targeting either HER2 or TROP2 outperformed each monotherapy with respect to antitumor outcomes in different animal experiments. The preclinical evidence for the dual regimen of IN10018 and ADCs warrants a further validation in clinical settings. Citation Format: Baoyuan Zhang, Zhixiang Zhang, Jiaming Gao, Shiqiang Lu, Ran Pang, Dongfang Li, Xun Huang, Natasha Qin, Leo Liu, Zaiqi Wang. Targeting FAK improves the tumor penetration of antibody-drug conjugates to strengthen the anti-cancer responses [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 4655.

30

Mir, Amin, Anuj Kumar, Reeta Chauhan, and Mohammad Waqar Ashraf. "Screening of Stem Extracts of Plumbago Zeylanica for Phytochemical, Antimicrobial and Anti-Arthritis Activity." Biomedical and Pharmacology Journal 13, no. 4 (December 30, 2020): 1709–18. http://dx.doi.org/10.13005/bpj/2045.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

The plant Plumbago Zeylanica is known for its traditional medicinal use because of its wide phytochemical constituency. On same basis its screening for anti-microbial and anti-arthritis activity was carried out. The results showed that the stem of Plumbago Zeylanica could be used as best remedy against bacterial and fungal originated diseases. Among plant extracts, chloroform extract showed highest rate of inhibition against all the concerned bacterial strains followed by petroleum ether extract. The water extract did not show much response as an antimicrobial agent. Also the antifungal activity was observed for all the extracts, but ethanolic extract showed more inhibition potential followed by petroleum ether extract. The results of anti-arthritis activity shows, lowest IC50 (46.55) value for water extract, hence high inhibition potential, followed by ethanolic extract (IC50) 48.50. Over all the plant showed good response as biomedicine against microbial originated diseases and against arthritis.

31

Al-Din Abdul Rahman, Harith B., and Hassan H. Hajim. "Effect of Organic Fertilization and Mulching on Growth and Yield of Brassica Olerracea L. Var. Capitata." IOP Conference Series: Earth and Environmental Science 910, no. 1 (November 1, 2021): 012079. http://dx.doi.org/10.1088/1755-1315/910/1/012079.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Abstract The experiment was carried out at the Research Station of the Department of Horticulture dept. of Tikrit University for the season 2020-2021 to investigate the effect of organic fertilization with treatments (control, poultry manure, and Humobacter fertilizer) and mulching type with four Mulching type (no mulching, black mulch, white mulch, and yellow mulch). A randomized complete blocks (RCBD) design and a split-plot method were used in the experiment, which included three replications. The Humobacter fertilizer treatment considerably outperformed of plant height, and overall plant yield, which were 21.69 cm, and 46.55 tons -1, respectively, compared to 19.03 cm, and 28.10 tons -1, respectively, As for the mulch treatments, the yellow mulch treatments were achieved the best values of number leaves, plant yield for one plant and the total plant yield, 16.81 leaf-1, 50.38 cm, 1.42 kg and 47.31 tons -1, respectively.

32

Sharma, Indu, and Rani Dhanze. "A checklist of the ornamental fishes of Himachal Pradesh, the western Himalaya, India." Journal of Threatened Taxa 10, no. 8 (July 26, 2018): 12108. http://dx.doi.org/10.11609/jott.3716.10.8.12108-12116.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Fifty-eight ornamental fish species belonging to five orders, 13 families and 36 genera occur in Himachal Pradesh. The dominant family is Cyprinidae (46.55%) followed by Nemacheilidae (15.51%); Sisoridae, Poeciliidae, Osphronemidae (9.89%); Cobitidae (5.17%); Amblycipitidae, Ambassidae, Badidae, Gobiidae, Helostomatidae, Cichlidae and Characidae (1.72%). Of the 58 species, 27.58% are exotic and have been mainly imported for aquarium keeping. The exotic species are being introduced in the region without any regulation, subsequently turning invasive and threatening the indigenous fauna. Thus, there is a need for developing scientific guidelines and regulatory mechanisms for importing exotic aquarium fishes. On the other hand, the breeding and culture of indigenous fishes can be a profitable venture, provided there is an availability of a standardized breeding technology. Such an enterprise will go a long way in conservation of native fishes, improving livelihoods as well as raising the socio-economic status of local communities.

33

Rochelle, Tina L., Steven M. Shardlow, and Sik Hung Ng. "Using the Theory of Planned Behaviour to Explain Use of Traditional Chinese Medicine among Hong Kong Chinese in Britain." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–6. http://dx.doi.org/10.1155/2015/564648.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

The UK Chinese are known for their underutilisation of western healthcare services. Reasons for this underutilisation are complex. The Theory of Planned Behaviour (TPB) is a widely used model of social cognition, which in the present study is being applied to traditional Chinese medicine (TCM) utilisation and satisfaction with TCM services. Two hundred and seventy-two UK Chinese aged between 15 and 91 years (M=46.55; SD = 18.53) enrolled in the study. TCM utilisation was associated with gender, age, cultural attachment, and subjective norms. TCM users were more likely to be female and older and have a strong attachment to Chinese culture, and be influenced by the views of important others. Findings highlight the potential of the TPB in exploring TCM utilisation, whilst also throwing light on other factors influential in the use of TCM and satisfaction with TCM service provision among Chinese in the UK.

34

COHEN, ROSA GRACIELA. "A new species of Branchinecta (Crustacea: Branchiopoda: Anostraca) from the Argentinian Tierra del Fuego." Zootaxa 1884, no. 1 (September 24, 2008): 60. http://dx.doi.org/10.11646/zootaxa.1884.1.4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Branchinecta fueguina, a new species of fairy shrimp, was found together with B. granulosa in a temporary pond beside Laguna de los Cisnes, 53°47'12''S, 67°46'55''W, Tierra del Fuego, Antártida e Islas del Atlántico Sur Province (Argentina). The male second antennal basal article has a proximal, anteriomedial auriculate welt, covered with sensory setae and a hanging posteriomedial ornamented apophysis bending abruptly anteriorly with a rounded apex. Distally, the basal article has a longitudinal medial crest, proximally produced into a blunt posteriomedially directed point. The distal article is strongly rotated, articulating almost perpendicular to the basal article. The anterior surface of the article is triangular, from its proximal joint to the broadly explanate apex. Distally, the broadened article bends anteriorly forming a complex three-lobed apex. The peculiar joint with the basal article and the distal article shape are unique in the genus.

35

Mir, Amin, Anuj Kumar, Reeta Chauhan, and Mohammad Waqar Ashraf. "Screening of Stem Extracts of Plumbago Zeylanica for Phytochemical, Antimicrobial and Anti-Arthritis Activity." Biomedical and Pharmacology Journal 13, no. 4 (December 30, 2020): 1709–18. http://dx.doi.org/10.13005/bpj/2045.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

The plant Plumbago Zeylanica is known for its traditional medicinal use because of its wide phytochemical constituency. On same basis its screening for anti-microbial and anti-arthritis activity was carried out. The results showed that the stem of Plumbago Zeylanica could be used as best remedy against bacterial and fungal originated diseases. Among plant extracts, chloroform extract showed highest rate of inhibition against all the concerned bacterial strains followed by petroleum ether extract. The water extract did not show much response as an antimicrobial agent. Also the antifungal activity was observed for all the extracts, but ethanolic extract showed more inhibition potential followed by petroleum ether extract. The results of anti-arthritis activity shows, lowest IC50 (46.55) value for water extract, hence high inhibition potential, followed by ethanolic extract (IC50) 48.50. Over all the plant showed good response as biomedicine against microbial originated diseases and against arthritis.

36

Colquhoun, David. "Unfair exchange." Nature 402, no. 6759 (November 1999): 230. http://dx.doi.org/10.1038/46155.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Jones, David. "Internal ecology." Nature 402, no. 6760 (November 1999): 367. http://dx.doi.org/10.1038/46455.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Burt, David W., Charlotte Bruley, Ian C. Dunn, Cheryl T. Jones, Anne Ramage, Andy S. Law, David R. Morrice, et al. "The dynamics of chromosome evolution in birds and mammals." Nature 402, no. 6760 (November 1999): 411–13. http://dx.doi.org/10.1038/46555.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Dalton, Rex. "Geographer sues critics of his rock-dating methods." Nature 401, no. 6752 (September 1999): 419. http://dx.doi.org/10.1038/46655.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Cherry, Michael. "South Africa says AIDS drug ‘toxic’." Nature 402, no. 6757 (November 1999): 3. http://dx.doi.org/10.1038/46855.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Yano, Rina, Junko Terada-Hirashima, Yukari Uemura, Noriko Tomita, Yosuke Shimizu, Haruka Iwasaki, Nobumasa Okumura, et al. "Efficacy and Safety of the Smallpox Vaccine for Postexposure Prophylaxis in Monkeypox: Protocol for an Open-Labeled, Single-Armed Study." JMIR Research Protocols 12 (August 25, 2023): e46955. http://dx.doi.org/10.2196/46955.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Background In May 2022, a case of monkeypox (currently known as “mpox”) with no history of overseas travel was reported in the United Kingdom, followed by reports of infections reported in Europe, the United States, and other countries worldwide. Due to the significant overlap in immune responses among viruses of the genus Orthopoxvirus (including smallpox virus, mpox virus, and vaccinia virus), it is believed that cross-immunity can be achieved by administering the smallpox virus vaccine. In Japan, a smallpox vaccine (LC16m8 strain vaccine) has been approved; however, there was no regulatory approval for the mpox vaccine during the design of this study. Although it is believed that individuals exposed to the mpox virus may receive smallpox vaccination as mpox prophylaxis, the existing evidence is not clear. Objective The primary objective was to evaluate the efficacy of the LC16m8 strain vaccine, approved for smallpox in Japan, for postexposure prophylaxis against mpox when administered to close contacts of individuals with mpox. The secondary objective was to investigate the safety of the vaccine for postexposure prophylaxis against mpox. Methods The study aimed to enroll 100 vaccinated participants who had been identified as close contacts of individuals with mpox. Consent was obtained, and the participants are inoculated with the vaccine. Daily recordings of symptoms (body temperature, headache, rash, and side effects) were made until day 21 and then again on day 28. Furthermore, additional evaluations of adverse events were performed by the investigators on days 7, 14, 21, and 28. Considering that the maximum incubation period for mpox is 21 days, the primary end point is the presence or absence of the disease 21 days after close contact. The primary analysis focused on cases within 4 days of intense contact as it has been reported that vaccination within this timeframe can reduce the incidence of the disease. Results The first trial participant was enrolled on July 28, 2022, and the research period concluded in March 2023. The study results will be published in a peer-reviewed scientific journal. Conclusions This study allowed us to investigate the efficacy and safety of the LC16m8 strain vaccine in postexposure prophylaxis against mpox. Trial Registration Japan Registry of Clinical Trials jRCTs031220137; https://jrct.niph.go.jp/en-latest-detail/jRCTs031220137 International Registered Report Identifier (IRRID) DERR1-10.2196/46955

42

Weitzman, Elissa R., Machiko Minegishi, Rachele Cox, and Lauren E. Wisk. "Associations Between Patient-Reported Outcome Measures of Physical and Psychological Functioning and Willingness to Share Social Media Data for Research Among Adolescents With a Chronic Rheumatic Disease: Cross-Sectional Survey." JMIR Pediatrics and Parenting 6 (December 6, 2023): e46555-e46555. http://dx.doi.org/10.2196/46555.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Abstract Background Social media data may augment understanding of the disease and treatment experiences and quality of life of youth with chronic medical conditions. Little is known about the willingness to share social media data for health research among youth with chronic medical conditions and the differences in health status between sharing and nonsharing youth with chronic medical conditions. Objective We aimed to evaluate the associations between patient-reported measures of disease symptoms and functioning and the willingness to share social media data. Methods Between February 2018 and August 2019, during routine clinic visits, survey data about social media use and the willingness to share social media data (dependent variable) were collected from adolescents in a national rheumatic disease registry. Survey data were analyzed with patient-reported measures of disease symptoms and functioning and a clinical measure of disease activity, which were collected through a parent study. We used descriptive statistics and multivariate logistic regression to compare patient-reported outcomes between youth with chronic medical conditions who opted to share social media data and those who did not opt to share such data. Results Among 112 youths, (age: mean 16.1, SD 1.6 y; female: n=72, 64.3%), 83 (74.1%) agreed to share social media data. Female participants were more likely to share (P=.04). In all, 49 (43.8%) and 28 (25%) participants viewed and posted about rheumatic disease, respectively. Compared to nonsharers, sharers reported lower mobility (T-score: mean 49.0, SD 9.4 vs mean 53.9, SD 8.9; P=.02) and more pain interference (T-score: mean 45.7, SD 8.8 vs mean 40.4, SD 8.0; P=.005), fatigue (T-score: mean 49.1, SD 11.0 vs mean 39.7, SD 9.7; P<.001), depression (T-score: mean 48.1, SD 8.9 vs mean 42.2, SD 8.4; P=.003), and anxiety (T-score: mean 45.2, SD 9.3 vs mean 38.5, SD 7.0; P<.001). In regression analyses adjusted for age, sex, study site, and Physician Global Assessment score, each 1-unit increase in symptoms was associated with greater odds of willingness to share social media data, for measures of pain interference (Adjusted Odds Ratio [AOR] 1.07, 95% CI 1.001-1.14), fatigue (AOR 1.08, 95% CI 1.03-1.13), depression (AOR 1.07, 95% CI 1.01-1.13), and anxiety (AOR 1.10, 95% CI 1.03-1.18). Conclusions High percentages of youth with rheumatic diseases used and were willing to share their social media data for research. Sharers reported worse symptoms and functioning compared to those of nonsharers. Social media may offer a potent information source and engagement pathway for youth with rheumatic diseases, but differences between sharing and nonsharing youth merit consideration when designing studies and evaluating social media–derived findings.

43

Orlando, Tânia das Graças Silva, Mário José Pedro Júnior, Antônio Odair Santos, and José Luiz Hernades. "Comportamento das cultivares Cabernet Sauvignon e Syrah em diferentes porta-enxertos." Ciência e Agrotecnologia 32, no. 3 (June 2008): 749–55. http://dx.doi.org/10.1590/s1413-70542008000300007.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

As cultivares Cabernet Sauvignon e Syrah são destinadas à elaboração de vinhos tintos jovens ou de guarda bastante difundidas em diversas zonas vitivinícolas de todo o mundo. No Brasil, são utilizadas principalmente no Rio Grande do Sul e Vale do Rio São Francisco. Atualmente, produtores da região de Jundiaí, SP, têm demonstrado interesse na utilização de tais cultivares com intuito de obter vinhos de qualidade superior aos originários de cultivares americanas. Por isso, realizou-se o estudo do comportamento das cultivares Cabernet Sauvignon e Syrah em diferentes porta-enxertos, na região de Jundiaí, SP (23º06' S; 46º55' W, 715 m). Não houve influência dos diferentes porta-enxertos sobre o comportamento da cultivar Cabernet Sauvignon. O porta-enxerto IAC 571-6 'Jundiaí' tendeu a conferir colheita tardia na cultivar Syrah. Os porta-enxertos IAC 572 'Jales' e IAC 571-6 'Jundiaí' conferiram maior produção a cultivar Syrah. A cultivar Syrah apresentou-se como boa opção de plantio para obtenção de vinho de qualidade na região.

44

Uddin, A. B. M. Sharif, M. M. Rahman, M. B. Alam, and M. H. K. Kamaly. "Adoption of production technologies by potato growers in northwest Bangladesh." Rajshahi University Journal of Life & Earth and Agricultural Sciences 41 (December 19, 2015): 29–39. http://dx.doi.org/10.3329/rujleas.v41i0.21622.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Determining the extent of adoption of modern variety potato production technologies by the potato growers was the main focus of the study. The study was conducted in the Rajshahi district. Out of 1547 potato growers, 232 respondents were randomly selected as a sample for data collection from twenty villages. A pre-tested interview schedule was used to collect data from the respondents during July 2010 to February 2011. For measuring the adoption of modern variety potato production technologies by the potato growers, 11 technologies on modern potato production were considered. Majority (46.55%) of the growers had medium adoption compared to high (29.74%) and low (23.71%) adoption. Among the extent of adoption of eleven selected technologies recommended irrigation was at top highest ranking as indicated by the adoption index where as plant spacing was bottom lowest. The adoption variations in different technologies will not be improved unless effective steps are taken to increase growers exposure to get benefits of using such technologies as per recommendations.

45

DADARLAT, MARIUS, and SØREN EILERS. "ON THE CLASSIFICATION OF NUCLEAR C*-ALGEBRAS." Proceedings of the London Mathematical Society 85, no. 1 (March 2002): 168–210. http://dx.doi.org/10.1112/s0024611502013679.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

We employ results from KK-theory, along with quasidiagonality techniques, to obtain wide-ranging classification results for nuclear C*-algebras. Using a new realization of the Cuntz picture of the Kasparov groups we show that two morphisms inducing equal KK-elements are approximately stably unitarily equivalent. Using K-theory with coefficients to associate a partial KK-element to an approximate morphism, our result is generalized to cover such maps. Conversely, we study the problem of lifting a (positive) partial KK-element to an approximate morphism. These results are employed to obtain classification results for certain classes of quasidiagonal C*-algebras introduced by H. Lin, and to reprove the classification of purely infinite simple nuclear C*-algebras of Kirchberg and Phillips. It is our hope that this work can be the starting point of a unified approach to the classification of nuclear C*-algebras.2000 Mathematical Subject Classification: primary 46L35; secondary 19K14, 19K35, 46L80.

46

Ashraf Jamal Mahmoud, Alae Imad Tawfiq, Alham Aied Assad, and Thabt Muthehar Khalaf. "parasitic infection in Musca domestica which isolated from Tikrit city." Tikrit Journal of Pure Science 23, no. 5 (January 18, 2023): 7–12. http://dx.doi.org/10.25130/tjps.v23i5.580.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

The targeted of this research is investigating the parasitic stages transmitted by body houseflies parts Musca domestica. Where samples were collected from some areas of Tikrit city in Salahuddin province. from October 2013 until January 2014. through immersion insect in physiological solution to see the types of parasitic stages.where the proportion for sites of outside home 37.93% while the sites of inside house rate was 15.51%, and samples of butcher shops rate was 46.55%.And diagnosed some parasitic stages and the rate of infection was 24%, the parasites are: Entamoeba histolytica 9.33%, Endolamix nana 2% , Iodamoeba butschlii 7.33% and egg Ascaris lumbricoides 5.33%. The results also show that the number of parasitic flies on the body of roles after dipping lower than before dowsing, and these numbers vary from part to part, where the setup was more, especially in the rest of the body samples flies right wing and the left wing and legs samples were prepared less.

47

Мальчиков, Роман, Юсупжан Юлдашбаев, Турсумбай Кубатбеков, Ринат Гадиев, Наиль Губайдуллин, Вадим Яремко, and Абдугани Абдурасулов. "ВЕСОВОЙ РОСТ БАРАНЧИКОВ РОМАНОВСКОЙ ПОРОДЫ И ЕЁ ПОМЕСЕЙ С ЭДИЛЬБАЕВСКОЙ." Вестник Ошского государственного университета. Сельское хозяйство: агрономия, ветеринария и зоотехния, no. 1 (November 30, 2022): 68–78. http://dx.doi.org/10.52754/16948696_2022_1_8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Приводятся результаты изучения абсолютного, среднесуточного прироста живой массы, относительной скорости роста и коэффициента увеличения массы тела чистопородных баранчиков романовской породы и её помесей первого и второго поколений с эдильбаевской породой. Установлено, что величина абсолютного прироста живой массы за период выращивания от рождения до 10 мес у чистопородных баранчиков романовской породы составляла 35,56 кг, помесей первого поколения с эдильбаевской породой (½ эдильбай × ½ романовская) – 46,55 кг, помесей второго поколения (¾ эдильбая × ½ романовская). Аналогичный ранг распределения баранчиков подопытных групп отмечался и по уровню среднесуточного прироста живой массы. При этом у чистопородных баранчиков романовской породы его величина за период выращивания от рождения до 10 мес составляла 118,5 г, помесей первого поколения – 155,2 г, помесей второго поколения – 159,7 г. Аналогичные межгрупповые различия отмечались по относительной скорости роста и уровню коэффициента увеличения живой массы с возрастом. Так за период опыта от рождения до 10 мес. у чистопородных баранчиков романовской породы величина первого показателя составляла 166,71 %, второго – в 10 мес. – 11,02, у помесей первого поколения соответственно 170,61 % и 12,61, помесей второго поколения – 169,69 % и 12,20.

48

Lan, K., J. Zhou, F. Yang, and J. Wang. "P1.14-21 Propensity-Matched Genomic Profiling Comparison of Lung Adenocarcinomas Among 3 Races, a Multicenter Study of 4655 Patients." Journal of Thoracic Oncology 14, no. 10 (October 2019): S561. http://dx.doi.org/10.1016/j.jtho.2019.08.1172.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Abushukair, Hassan Mohammed, Ayah Al-Bzour, Andrew Knight, Walter J. Storkus, John M. Kirkwood, and Lilit Karapetyan. "Abstract 4655: The prognostic significance of a 12-chemokine tertiary lymphoid structure (TLS) gene signature in uveal melanoma (UM)." Cancer Research 83, no. 7_Supplement (April 4, 2023): 4655. http://dx.doi.org/10.1158/1538-7445.am2023-4655.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Abstract Introduction Lymphoid aggregates are commonly associated with better prognosis and enhanced response to immune modulators in several cancers. Considering the immune-privileged status of the eye we sought to investigate the immune, genomic and prognostic significance of 12-chemokine TLS gene signature in UM patients. Methods A previously validated 12-chemokine gene signature established in cutaneous melanoma was used (CCL2-5, CCL8, CCL18, CCL19, CCL21, CXCL9-11, CXCL13). Clinical, genomic and transcriptomic data was retrieved from The Cancer Genomic Atlas UM cohort (n = 80) and the GSE22138 dataset (n = 63) from the gene expression omnibus. The signature was constructed using principal component (PC) analyses based on the first PC1. Patients with a PC1 score > +4 or < -4 were considered gene expression profile (GEP) high and low, respectively. The CIBERSORT algorithm was used to estimate the immune composition in tumor tissue. Gene Set Enrichment Analysis (GSEA) was conducted using the Hallmarks gene sets. A cytotoxic T cell (CTL) score was calculated based on the coordinate expression of CD8A, CD8B, GZMA, GZMB and PRF1. Results The 12-chemokine score was higher among epithelioid vs. spindle cell or mixed histology (mean: 7.84 vs -4.91 vs 1.22, p = 0.038) and there were no differences across different tumor sites or stages. GEP low patients had significantly better overall survival (HR: 0.10, 95% CI: 0.03-0.36, p < 0.001) and disease-free survival (HR: 0.23, 95% CI: 0.06-0.88, p = 0.031) compared to GEP high. Metastasis-free survival was not significantly different in the second cohort (0.47, 95% CI: 0.16-1.42, p = 0.182). The EIF1AX and SF3B1 driver mutations were significantly more frequent among GEP low (22.5% and 35%) compared to GEP high patients (3.7% and 7.4%). Tumor mutational burden and other driver mutations (BAP1, GNA11, GNAQ) were similar between both groups. GSEA revealed significant enrichment of inflammatory response (IFN-α/γ, TNF-α signalling via NF-κB, IL2-STAT5, IL6-JAK-STAT3 signalling), Epithelial Mesenchymal Transition (EMT), reactive oxygen species, and angiogenesis pathways in GEP high patients. GEP low patients had lower CTL scores compared to GEP high patients (31.3 vs 11.4, p < 0.001). M1 macrophages, CD8+ and regulatory T cells were enriched in GEP high patients whereas CD4+ memory T cells and activated dendritic cells were more prevalent in GEP low patients. Conclusion Uveal melanoma patients with a high GEP score had inferior survival and were enriched for inflammatory, angiogenic, and EMT pathways, while patients with a low GEP score were more likely to express prognostically favourable driver mutations (EIF1AX, SF3B1). Our results suggest a variable prognostic role of lymphoid aggregates in the setting of UM compared to other solid tumors, warranting further investigation for their differential underlying mechanisms. Citation Format: Hassan Mohammed Abushukair, Ayah Al-Bzour, Andrew Knight, Walter J. Storkus, John M. Kirkwood, Lilit Karapetyan. The prognostic significance of a 12-chemokine tertiary lymphoid structure (TLS) gene signature in uveal melanoma (UM). [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 4655.

50

Iavinskii, A. V. "Influence of anthropogenic waste of different genesis on properties of fine-grained concrete." Russian Automobile and Highway Industry Journal 20, no. 3 (July 18, 2023): 396–404. http://dx.doi.org/10.26518/2071-7296-2023-20-3-396-404.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Abstract:

Introduction. The growing amount of stored waste from TPPs has a negative impact on the environmental and economic situation in Russia. The content of ash dumps leads to pollution of nearby areas and increase in energy prices. To solve this problem, it is proposed to use TPP waste as a component of solutions. Materials and methods. The equipment on which the experiment was performed is listed. For the test of compressive strength, the press TP-1-350 Universal was used. For the test of flexural strength, MII-100 machine was used. Specific surface area of TPP waste was determined on PSKh-12 device. The samples gained the strength in the chamber of normal hardening. The chemical composition of TPP waste was determined by the X-ray fluorescent method. Results. The experimental data on the strength of specimens with the replacement of part of the cement by waste thermal power plants of different genesis are presented. The part of the samples were cured under normal conditions, and part was subjected to heat and humidity treatment. Specific cement consumption per unit of compressive and flexural strength was calculated. Compressive strength of mortars with replacement of 20% of cement by Kuznetsky TPP ash makes it possible to obtain samples with strength by 8% less than the control sample under normal curing conditions. The use of acid ash from Omsk TPP and Kuznetsky TPP under heat and moisture treatment makes it possible to obtain the samples with compressive strength higher than the control sample up to 13%. The introduction of 30 % of the basic ash from Novosibirsk TPP instead of cement allows to obtain samples with compressive strength up to 46,55 MPa. The calculation of specific consumption of cement per unit strength showed that the use of the proposed compositions is more cost-effective than the control ashless sample up to 30%. Discussion and conclusions. It has been proved that replacement of up to 30% of cement by TPP wastes makes it possible to obtain mortars with strength not lower than that of the control cement sample. Depending on curing conditions and the type of used TPP waste it is possible to receive samples with compressive strength up to 46,55 MPa and bending strength up to 9,31 MPa. It was found that the use of heat and moisture treatment for the samples using basic ash does not give an increase in strength, compared to acidic ash.

Journal articles on the topic '46L55'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles