Academic literature on the topic '401-500'

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Journal articles on the topic "401-500"

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Bin-Jaliah, Ismaeel. "Natural Hypoxia is Not a Limiting Factor in Evaluating the Novel Arylidene Derivative MLT-401 Against an In Vitro Colorectal Cancer Model." Cellular Physiology and Biochemistry 46, no. 5 (2018): 2082–89. http://dx.doi.org/10.1159/000489448.

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Background/Aims: Cancer cells in vivo develop resistance to many anti-tumor drugs. One known factor to influence such drug resistance is hypoxia, which is an important component of the tumor microenvironment. Standard cancer lines mostly do not exhibit a cellular hypoxic microenvironment and there is a paucity of information on the efficacy of lead molecules in both cellular- and environment-induced hypoxic conditions. Therefore, in the present study, we have evaluated the efficacy of the arylidene derivative MLT-401, a lead molecule showing activity against colorectal cancer model using the HCT 116 cell line and CCD-80-C control cells in normoxic and natural (marginal) hypoxic conditions, which is usually observed in high-altitude regions. Methods: The efficacy of MLT-401 on HCT 116 and CCD-80-C cells were tested in both normoxia and marginal hypoxia conditions. MTT assay was used to evaluate cell proliferation, Annexin V binding assay for apoptotic cell quantification and PI staining for cell cycle were done by flow cytometry. Induction of pro-apoptotic marker BAX and anti-apoptotic Bcl-2 were assessed by western blot. Bcl-2/BAX ratio was calculated based on protein expression by western blotting and bands were quantified by Image J software. Results: Analysis of cell proliferation showed an average 10-fold reduction in the inhibition of HCT 116 cells in hypoxic conditions with approximately 500 nM MLT-401, while there was no significant change noted in marginal hypoxic conditions. A proportionate increase in the number of apoptotic cells and large M4 fraction of 10.5% and 26.7% of HCT116 against 6.3% of control cells in cell cycle assessment with MLT-401 concentrations ranging from 250 to 500 nM respectively clearly demonstrated anti-cancer activity. A Bcl-2/BAX ratio of < 1 showed that the induction of apoptosis was the gross mechanism underlying the inhibition of HCT 116 cells by MLT-401. Conclusion: Collectively, these results show MLT-401 as an effective anti-colorectal cancer lead molecule irrespective of normoxia or natural hypoxia.
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Cruz, Rosângela, Ady BARROS, Alba Valeria Alves Ignácio, and Marcelo Sergio da Luz Cruz. "Percepção das crianças da Escola Municipal “Centro de Promoção Educacional” do Estatuto Criança e Adolescente." Concilium 22, no. 4 (June 8, 2022): 933–44. http://dx.doi.org/10.53660/clm-401-500.

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Apresenta-se no Artigo o resultado da Pesquisa Bibliográfica e de Campo desenvolvida durante o Curso Gestão Escolar, na Escola Municipal de Ensino Fundamental, do Centro de Promoção Educacional, de Apiacás-MT, a percepção das crianças, a partir dos 10 anos, sobre o que sabem dos seus direitos previstos em Lei, especialmente no ECA. Foi de suma importância a pesquisa para a Gestão Escolar rever seu Projeto Político Pedagógico, bem como a sua relação compromisso ético, cidadão com as crianças/adolescentes e seus familiares/comunidade escolar.
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Yuliani, Yuliani, Ika Friscila, and Frani Mariana. "KONSUMSI JANTUNG PISANG TERHADAP RERATA PENINGKATAN PRODUKSI ASI PADA IBU MENYUSUI." Jurnal Kebidanan Khatulistiwa 9, no. 2 (December 11, 2023): 52. http://dx.doi.org/10.30602/jkk.v9i2.1210.

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Latar belakang : ASI eksklusif sangat bermanfaat bagi bayi, dampak yang dapat terjadi apabila bayi tidak diberikan ASI eksklusif adalah meningkatnya angka kesakitan dan kematian bayi. Pemberian ASI eksklusif 6 bulan merupakan investasi terbaik bagi kesehatan dan kecerdasan anak. Jantung pisang merupakan bagian dari tanaman pisang yang dimanfaatkan untuk meningkatkan produksi ASI. Dipilih karena harganya murah dan sangat mudah didapatkan. Tujuan: Mengetahui konsumsi jantung pisang terhadap rerata peningkatan produksi ASI pada ibu menyusui di Wilayah Kerja Puskesmas Murung Pudak. Metode: Menggunakan eksperimen semu dengan rancangan berbentuk pretest-posttest with control group design menggunakan dua jenis perlakuan. Kelompok konsumsi jantung pisang sebanyak 200 gr 2 kali sehari. Hasil Penelitian: Rerata produksi ASI sebelum perlakuan rentang 401-500 cc dengan nilai rerata 496,6667, rerata produksi ASI sesudah perlakuan rentang 801-900 cc dengan nilai rerata 816,6667, rerata produksi ASI pada kelompok kontrol rentang 401-500 cc dengan nilai rerata 453,333 pada ibu menyusui di Wilayah Kerja Puskesmas Murung Pudak. Kesimpulan : Konsumsi jantung pisang terbukti meeningkatkan produksi ASI pada kelompok perlakuan ibu menyusui di wilayah kerja Puskesmas Murung Pudak.
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Begg, Gavin A. "Reproductive biology of school mackerel (Scomberomorus queenslandicus) and spotted mackerel (S. munroi) in Queensland east-coast waters." Marine and Freshwater Research 49, no. 3 (1998): 261. http://dx.doi.org/10.1071/mf97187.

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Spatial and temporal spawning patterns of school mackerel (Scomberomorus queenslandicus) and spotted mackerel (S. munroi) in Queensland east-coast waters, Australia, (16˚S to 28˚S), were examined to provide reproductive parameters required for the management and protection of spawning stocks. School mackerel spawned along the Queensland coastline from October to January. Female school mackerel were sexually mature between 401 and 450 mm, and males between 351 and 400 mm LCF (length to caudal fork). In contrast, spotted mackerel spawned in northern Queensland waters from August to October. Females were between 451 and 500 mm, and males 401 and 450 mm LCF at first maturity. Both species were found to be dioecious. Differential spawning patterns of school and spotted mackerel may help the species coexist and maintain the integrities of the species and their respective stock structures.
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Xuzhang, Wendi, Huayan Huang, Yongfeng Yu, Lan Shen, Ziming Li, and Shun Lu. "Treatment strategies based on different oligoprogressive patterns after immunotherapy failure in metastatic NSCLC." Therapeutic Advances in Medical Oncology 15 (January 2023): 175883592311563. http://dx.doi.org/10.1177/17588359231156387.

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Background: Oligoprogressive disease is recognized as the overall umbrella term; however, a small number of progressions on imaging can represent different clinical scenarios. This study aims to explore the optimal treatment strategy after immunotherapy (IO) resistance in advanced non-small-cell lung cancer (NSCLC), especially in personalized therapies for patients with different oligoprogressive patterns. Methods: Based on European Society for Radiotherapy and Oncology/European Organization for Research and Treatment of Cancer consensus, metastatic NSCLC patients with cancer progression after IO resistance were divided into four patterns, repeat oligoprogression (REO, oligoprogression with a history of oligometastatic disease), induced oligoprogression (INO, oligoprogression with a history of polymetastatic disease), de-novo polyprogression (DNP, polyprogression with a history of oligometastatic disease), and repeat polyprogression (REP, polyprogression with a history of polymetastatic disease). Patients with advanced NSCLC who received programmed cell death-1/programmed cell death ligand-1 inhibitors between January 2016 and July 2021 at Shanghai Chest Hospital were identified. The progression patterns and next-line progression-free survival (nPFS), overall survival (OS) were investigated stratified by treatment strategies. nPFS and OS were calculated using the Kaplan–Meier method. Results: A total of 500 metastatic NSCLC patients were included. Among 401 patients developed progression, 36.2% (145/401) developed oligoprogression and 63.8% (256/401) developed polyprogression. Specifically, 26.9% (108/401) patients had REO, 9.2% (37/401) patients had INO, 27.4% (110/401) patients had DNP, and 36.4% (146/401) patients had REP, respectively. The patients with REO who received local ablative therapy (LAT) had significant longer median nPFS and OS compared with no LAT group (6.8 versus 3.3 months; p = 0.0135; OS, not reached versus 24.5 months; p = 0.0337). By contrast, there were no nPFS and OS differences in INO patients who received LAT compared with no LAT group (nPFS, 3.6 versus 5.3 months; p = 0.3540; OS, 36.6 versus 45.4 months; p = 0.8659). But in INO patients, there were significant longer median nPFS and OS using IO maintenance by contrast with IO halt treatment (nPFS, 6.1 versus 4.1 months; p = 0.0264; OS, 45.4 versus 32.3 months; p = 0.0348). Conclusions: LAT (radiation or surgery) is more important for patients with REO while IO maintenance plays a more dominant role in patients with INO.
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พงษ์สวัสดิ์, สืบพงษ์, and ธีรวิชญ์ วงษา. "การสำรวจแปลงปลูกป่าชาวบ้านในพื้นที่ศูนย์พัฒนาโครงการหลวงหมอกจ๋าม ด้วยเครื่องกำหนดพิกัดบนพื้นโลกด้วยดาวเทียมแบบมือถือ." Suranaree Journal of Social Science 15, no. 2 (September 21, 2021): 41–58. http://dx.doi.org/10.55766/midf3554.

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การวิจัยนี้มีวัตถุประสงค์เพื่อ 1) สำรวจแนวเขตแปลงปลูกป่าชาวบ้านด้วยเครื่องกำหนดพิกัดบนพื้นโลกด้วยดาวเทียมแบบมือถือ 2) จัดทำฐานข้อมูลแนวเขตแปลงปลูกป่าชาวบ้านด้วยระบบสารสนเทศภูมิศาสตร์ และ 3) วิเคราะห์อัตราการรอดตายของต้นพันธุ์ และความสัมพันธ์กับระยะห่างจากบ้านของเกษตรกร ความสูง และความลาดชัน ประชากรในการศึกษาครั้งนี้คือ เกษตรกรที่เป็นสมาชิกโครงการปลูกป่าชาวบ้านของศูนย์พัฒนาโครงการหลวงหมอกจ๋าม อำเภอแม่อาย จังหวัดเชียงใหม่ จำนวน 52 ราย ผลการวิจัยพบว่า การใช้เครื่องกำหนดพิกัดบนพื้นโลกด้วยดาวเทียมแบบมือถือเข้าไปสำรวจแนวเขตแปลงปลูกป่าของเกษตรกรทั้ง 52 ราย นำต้นพันธุ์ไปปลูกในที่ดินของตนเองจำนวน 61 แปลง รวมจำนวนต้นพันธุ์ 39,948 ต้น การปลูกแบ่งได้เป็น 2 แบบ คือ การปลูกแบบแนวรั้ว คิดเป็นร้อยละ 43 และการปลูกแบบแปลง คิดเป็นร้อยละ 57 โดยค่าพิกัดที่ได้จากเครื่องกำหนดพิกัดบนพื้นโลกด้วยดาวเทียมแบบมือถือมีความคลาดเคลื่อนเฉลี่ย 7.36 เมตร จากการวิเคราะห์ด้วยระบบสารสนเทศภูมิศาสตร์พบว่าทำเลที่ตั้งของแปลงปลูกป่าชาวบ้านมีการกระจุกตัวอยู่ใกล้กับชุมชน ที่มีระดับความสูงระหว่าง 401-500 เมตร จากระดับน้ำทะเลปานกลาง และมีร้อยละความลาดชันระหว่าง 35-50 ต้นจันทร์ทองเทศมีอัตราการรอดตายสูงที่สุด คือร้อยละ 77.59 อัตราการรอดตายมีความสัมพันธ์ในทิศทางเดียวกับระยะห่างจากบ้านของเกษตรกร ความสูง และความลาดชัน โดยมีค่าสหสัมพันธ์ (r) เท่ากับ 0.27 0.17 และ 0.26 ตามลำดับ แต่ค่าสัมประสิทธิ์การตัดสินใจ (r2) เท่ากับ 0.07 0.03 และ 0.07 จึงสรุปได้ว่าอัตราการรอดตายของต้นพันธุ์อาจไม่มีระดับความสัมพันธ์มากกับระยะห่างจากบ้านของเกษตกร ความสูง และความลาดชัน
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الصرصور, إبراهيم علي, محمد علي قاسم, and صابر السيد منصور. "امتزاز بعض أيونات المعادن الثقيلة على سطح طفلة مدينة درنة – ليبيا." Al-Mukhtar Journal of Sciences 20, no. 1 (December 31, 2008): 123–33. http://dx.doi.org/10.54172/mjsc.v20i1.825.

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تعد طفلة الكاولينيت من المواد رخيصة الثمن وتتواجد بوفرة كبيرة كما أن لها خواص سطحية مميزة تجعلها من المواد المازة الجيدة لذا تم أخذ عينات من طفلة الكاولينيت من مدينة درنة ومعالجتها حراريا عند درجة حرارة الغرفة و200 و 500 درجة مئوية . ولدراسة امتزاز العناصر الثقيلة على سطح الطفلة تم تحضير محاليل مائية من بعض أملاح الفلزات (النحاس ، النيكل والخارصين) وأظهرت نتائج أيزوثرم الإمتزاز أن السعة القصوى للإمتزاز هي 672 ، 620 و 589 (ppm) لأيونات النحاس والنيكل والخارصين على الترتيب بالنسبة لعينة الطفلة غير المعالجة حراريا ، وكانت 672 ، 500 و 459 (ppm) لعينة الطفلة المعالجة عند 200 درجة مئوية وكانت 427 ، 401 و 333 (ppm) لعينة الطفلة المعالجة عند 500 درجة مئوية . ومن خلال الدراسة كان ترتيب إمتزاز أيونات العناصر على الصورة التالية : النحاس > النيكل > الخارصين كما أن عينة الطفلة غير المعالجة حراريا أظهرت أعلى امتزاز وبمقارنة أيزوثرمات الإمتزاز لكل من فرندلك ولانجمير أظهرت النتائج أن امتزاز هذه العناصر يتبع أيزوثرم لانجمير نظرا لأنه يظهر أقل حيود .
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Hung-Lung, C., T. C. Chen, M. C. Tsai, and Y. L. Chen. "Adsorption characteristics of benzene on biosolid adsorbent." Water Science and Technology 47, no. 1 (January 1, 2003): 83–87. http://dx.doi.org/10.2166/wst.2003.0022.

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This study selected biosolids from a petrochemical wastewater treatment plant as the raw material. The sludge was immersed in 0 to 5 mol l-1 of ZnCl2 solutions and pyrolyzed at different temperatures. When the sludge was pyrolyzed for 30 min at temperatures of 400, 500, 600, and 700°C, the corresponding surface area of the biosolid adsorbent was 46, 401, 921, and 727 m2/g, respectively. Pore size analysis indicated that the mesopore (20 to 500 Å) contributed more than the macropore and micropore in the sludge pyrolytic residue. When the benzene influent concentration was 800 ppmv, the adsorption capacity ranged from 59 to 164 mg/g for different biosolid adsorbents. A larger BET surface area and smaller average pore diameter yielded a larger benzene adsorption capacity.
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Miura, Toshihiro, and Atsushi Kato. "Hypoglycemic Action of Embelia madagascariensis in Normal and Diabetic Mice." American Journal of Chinese Medicine 25, no. 02 (January 1997): 169–73. http://dx.doi.org/10.1142/s0192415x97000196.

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The hypoglycemic effect of Embelia madagascariensis (Myrsinaceae) was investigated in both normal and streptozotocin-induced diabetic mice. The methanol extract of leaves of Embelia madagascariensis (EL)(500 mg/kg) reduced the blood glucose of normal mice from 206 ± 9 to 137 ± 10 mg/100 ml 4 hours after intraperitoneal administration (P<0.001), and also significantly lowered the blood glucose of streptozotocin-induced diabetic mice from 570 ± 29 to 401 ± 59 mg/100 ml under similar conditions (P<0.05). EL also suppressed epinephrine-induced hyperglycemia in mice (control vs EL, P<0.01).
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Roy, Indranil, Manuel Marya, David Susnitzky, and Hong Qi Deng. "Comparative Performance of Three High-Strength Ni-Cr-Mo Alloys in Oilfield Simulated H2S Environment." Materials Science Forum 783-786 (May 2014): 1857–62. http://dx.doi.org/10.4028/www.scientific.net/msf.783-786.1857.

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Three Ni-Cr-Mo alloys with 140ksi minimum yield strength, namely 625Plus, 718, and 945X were tested in selected sour environments to evaluate and rank their environmentally-assisted cracking susceptibility. The testing revealed that none of the alloys, stressed to 90% of their actual yield point, cracked as a result of an agressive 30-day NACE level VII-modified environment (401 ± 9 oF, 500 psia H2S, 500 psia CO2 and 151,700 mg/liter chlorides). In a complementary attempt to rank the alloy cracking susceptiblity, quasi-static strain rate (SSR) tests per NACE TM0198-2004 were conducted in a modified H2S-saturated NACE TM0177 Solution A. Following a critical analysis of parameters such as time-to-failure (TTF), percentage reduction in ductility (%ε), percentage reduction of cross-sectional area (% RA) and fractomicrographs, 625Plus was confirmed to outperform its counterparts while some evidence of hydrogen embrittlement was found on 945X.
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Books on the topic "401-500"

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Tadmurī, ʻUmar. Tarājim al-ʻulamāʼ wa-al-aʻlām fī al-qarn al-khāmis al-Hijrī, 401-500 H. 8th ed. Bayrūt: al-Maktabah al-ʻAṣrīyah, 2010.

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Diodorus. The Persian wars to the fall of Athens : books 11-14.34 (480-401 BCE). Austin: University of Texas Press, 2009.

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Xenophon. Anabazis. Ni͡u︡ Ĭork: Naukove t-vo im. Shevchenka, 1986.

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Xenophon. Anabasis. Cambridge, Mass: Harvard University Press, 2001.

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Henkes, Kevin. Tal ŭl mŏgŭn agi koyangi. Sŏul-si: Piryongso, 2005.

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Xenophon. Anabasi. Torino: Unione tipografico-editrice torinese, 2002.

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Xenophon. Anabasis. Cambridge, Mass: Harvard University Press, 1998.

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Xenophon. Anabasis: Der Zug der Zehntausend : griechisch-deutsch. München: Artemis, 1990.

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Ingersoll, Glenn. Thousand 401-500. Independently Published, 2018.

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Powers, Christopher. Visual Exegesis Anthology, Vol. 5: 401 - 500. Independently Published, 2021.

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Book chapters on the topic "401-500"

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Rainsberger, Livia. "Fragen 401 bis 500: VERTRIEBSSTRATEGIE – 100 Fragen für die strategische Ausrichtung des Vertriebs." In Edition Sales Excellence, 145–82. Wiesbaden: Springer Fachmedien Wiesbaden, 2024. http://dx.doi.org/10.1007/978-3-658-43783-1_7.

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"Charters 401-500." In Diplomatarium of the Crusader Kingdom of Valencia, 344–444. Princeton University Press, 1991. http://dx.doi.org/10.1515/9781400860685.344.

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"Questions(401 - 500)." In Neurosurgery Practice Questions and Answers, edited by Mark Shaya, Remi Nader, and Anil Nanda. Stuttgart: Georg Thieme Verlag, 2005. http://dx.doi.org/10.1055/b-0034-87990.

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"Answers(401 - 500)." In Neurosurgery Practice Questions and Answers, edited by Mark Shaya, Remi Nader, and Anil Nanda. Stuttgart: Georg Thieme Verlag, 2005. http://dx.doi.org/10.1055/b-0034-87998.

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"(S. 401) - (S. 500)." In Das Danziger Pfundzollbuch von 1409 und 1411, 236–93. Köln: Böhlau Verlag, 2012. http://dx.doi.org/10.7788/boehlau.9783412214746.236.

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Abdul Mutalib, Noor Azira, Noor Aniza Abdul Rahim, and Ungku Fatimah Ungku Zainal Abidin. "Prevalence of Bacillus cereus in Ready-to-Eat Foods in Northern Perak, Malaysia." In Food Safety Practices in the Restaurant Industry, 26–40. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-7998-7415-7.ch002.

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Food poisoning cases in Malaysia showed an increasing trend every year where 496 episodes were reported in 2018 as compared to 401 episodes in the same week of the year 2017. Bacillus cereus is one of the foodborne pathogens related to food poisoning cases in Malaysia. The main cause for the outbreak of B. cereus is the unregulated temperature during holding time. This study was conducted to detect the presence of aerobic bacteria and B. cereus present in ready-to-eat food in Northern Perak. A total of 83 food samples were collected and analyzed for the microbial count. The result shows that aerobic bacteria and B. cereus were detected in 28% of the samples. B. cereus count in food samples tested ranged from 100 cfu/g to 42000 cfu/g, whereas the aerobic bacteria recorded a range of 500 cfu/g to 2100000 cfu/g. The highest percentage of B. cereus was found in rice-based food, followed by meat, poultry, and gravy dishes. Positive colonies of B. cereus were further tested for anti-microbial resistance profile. Most B. cereus isolates showed resistance to tetracycline and clindamycin.
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