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Dissertations / Theses on the topic '3D brain imaging'

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1

Matias, Correia T. M. "Assessment and optimisation of 3D optical topography for brain imaging." Thesis, University College London (University of London), 2010. http://discovery.ucl.ac.uk/19496/.

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Optical topography has recently evolved into a widespread research tool for non-invasively mapping blood flow and oxygenation changes in the adult and infant cortex. The work described in this thesis has focused on assessing the potential and limitations of this imaging technique, and developing means of obtaining images which are less artefactual and more quantitatively accurate. Due to the diffusive nature of biological tissue, the image reconstruction is an ill-posed problem, and typically under-determined, due to the limited number of optodes (sources and detectors). The problem must be re
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2

Law, Kwok-wai Albert, and 羅國偉. "3D reconstruction of coronary artery and brain tumor from 2D medical images." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31245572.

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3

Uthama, Ashish. "3D spherical harmonic invariant features for sensitive and robust quantitative shape and function analysis in brain MRI." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/438.

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A novel framework for quantitative analysis of shape and function in magnetic resonance imaging (MRI) of the brain is proposed. First, an efficient method to compute invariant spherical harmonics (SPHARM) based feature representation for real valued 3D functions was developed. This method addressed previous limitations of obtaining unique feature representations using a radial transform. The scale, rotation and translation invariance of these features enables direct comparisons across subjects. This eliminates need for spatial normalization or manually placed landmarks required in most convent
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4

Olivero, Daniel. "Traumatic brain injury biomarker discovery using mass spectrometry imaging of 3D neural cultures." Thesis, Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/41102.

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Biomarker research is of great interest in the field of traumatic brain injury (TBI), since there are numerous potential markers that may indicate central nervous system damage, yet the brain is normally well isolated and discovery is at its infancy. Traditional methods for biomarker discovery include time consuming multi step chromatographic mass spectrometery (MS) techniques or pre-defined serial probing using traditional assays, making the identification of biomarker panels limiting and expensive. These shortfalls have motivated the development of a MS based probe that can be embedded into
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5

MomayyezSiahkal, Parya. "3D stochastic completion fields for mapping brain connectivity using diffusion magnetic resonance imaging." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110445.

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This thesis proposes a novel probabilistic method for measuring anatomical connectivity in the brain based on measurements obtained from diffusion magnetic resonance imaging. We approach the problem of fibre tractography from the viewpoint that a computational theory should relate to the underlying quantity that is being measured--the anisotropic diffusion of water molecules in fibrous tissues. To achieve this goal, the prior probability of completion between two particular regions of interest is modelled by a 3D directional random walk, which is representative of the ensemble anisotropic disp
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Collins, D. Louis. "3D model-based segmentation of individual brain structures from magnetic resonance imaging data." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=28716.

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This thesis addresses a specific problem of model-based segmentation; namely, the automatic identification and delineation of gross anatomical structures of the human brain based on their appearance in magnetic resonance images (MRI). The approach developed in this thesis depends on a general, iterative, hierarchical registration procedure and a 3-D digital model of human brain anatomy that contains both volumetric intensity-based data and geometric atlas data that co-exist in a brain-based stereotaxic coordinate system. The model contains features derived from an MRI atlas of gross neuroanato
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7

Christopoulos, Charitos Andreas. "Brain disease classification using multi-channel 3D convolutional neural networks." Thesis, Linköpings universitet, Statistik och maskininlärning, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-174329.

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Functional magnetic resonance imaging (fMRI) technology has been used in the investigation of human brain functionality and assist in brain disease diagnosis. While fMRI can be used to model both spatial and temporal brain functionality, the analysis of the fMRI images and the discovery of patterns for certain brain diseases is still a challenging task in medical imaging. Deep learning has been used more and more in medical field in an effort to further improve disease diagnosis due to its effectiveness in discovering high-level features in images. Convolutional neural networks (CNNs) is a cla
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8

Mayerich, David Matthew. "Acquisition and reconstruction of brain tissue using knife-edge scanning microscopy." Texas A&M University, 2003. http://hdl.handle.net/1969.1/563.

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A fast method for gathering large-scale data sets through the serial sectioning of brain tissue is described. These data sets are retrieved using knife-edge scanning microscopy, a new technique developed in the Brain Networks Laboratory at Texas A&M University. This technique allows the imaging of tissue as it is cut by an ultramicrotome. In this thesis the development of a knife-edge scanner is discussed as well as the scanning techniques used to retrieve high-resolution data sets. Problems in knife-edge scanning microscopy, such as illumination, knife chatter, and focusing are discussed. Tec
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9

Heinzer, Stefan. "Hierarchical 3D imaging and quantification of brain microvasculature in a mouse model for Alzheimer's disease /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17293.

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10

Nguyen, Peter. "CANNABINOID RECEPTORS IN THE 3D RECONSTRUCTED MOUSE BRAIN: FUNCTION AND REGULATION." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2274.

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CB1 receptors (CB1R) mediate the psychoactive and therapeutic effects of cannabinoids including ∆9-tetrahydrocannabinol (THC), the main psychoactive constituent in marijuana. However, therapeutic use is limited by side effects and tolerance and dependence with chronic administration. Tolerance to cannabinoid-mediated effects is associated with CB1R adaptations, including desensitization (receptor-G-protein uncoupling) and downregulation (receptor degradation). The objectives of this thesis are to investigate the regional-specificity in CB1R function and regulation. Previous studies have invest
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11

Mercier, Chloé. "High-resolution 3D MRI reconstruction for brain development studies." Electronic Thesis or Diss., Ecole nationale supérieure Mines-Télécom Atlantique Bretagne Pays de la Loire, 2025. http://www.theses.fr/2025IMTA0466.

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L’IRM foetale est utilisée pour établir un diagnostic précoce en cas d’anomalies du développement cérébral. Cependant, les mouvements du foetus pendant l’acquisition induisent des artéfacts qui dégradent la qualité des images. Pour limiter ces artefacts, on utilise des séquences d’acquisition ultrarapides, acquérant plusieurs ensembles de coupes orthogonales (axial, sagittal, coronal). Cependant, le mouvement inter-coupes persiste. Si non corrigé, il engendre des artefacts dans la reconstruction 3D. Les méthodes traditionnelles de correction de mouvement reposent sur un processus itératif en d
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12

Rambani, Komal. "Thick brain slice cultures and a custom-fabricated multiphoton imaging system: progress towards development of a 3D hybrot model." Thesis, Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/22702.

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Development of a three dimensional (3D) HYBROT model with targeted in vivo like intact cellular circuitry in thick brain slices for multi-site stimulation and recording will provide a useful in vitro model to study neuronal dynamics at network level. In order to make this in vitro model feasible, we need to develop several associated technologies. These technologies include development of a thick organotypic brain slice culturing method, a three dimensional (3D) micro-fluidic multielectrode Neural Interface system (µNIS) and the associated electronic interfaces for stimulation and recording
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13

D'Souza, Aswin Cletus. "Automated counting of cell bodies using Nissl stained cross-sectional images." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-2035.

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14

Li, Fan. "Segmentation and Symbolic Representation of Brain Vascular Network : Application to ArterioVenous Malformations." Thesis, Paris Est, 2016. http://www.theses.fr/2016PESC1048/document.

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Le traitement et l’analyse d’images angiographiques rotationnelles 3D (3DRA) de haute résolution spatiale pour l’aide à la planification d’interventions en neuroradiologie interventionnelle est un domaine de recherche récent et en plein essor. Les neuroradiologues ont besoin d’outils interactifs pour la planification des procédures d’embolisation et l’optimisation du guidage de microcathéters durant les interventions endovasculaires. L’exploitation des données d’imagerie pour l’aide au diagnostic et la thérapeutique requiert le développement d’algorithmes robustes et de méthodes efficaces. Ces
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15

KAWAI, HISASHI, KIMINORI BOKURA, SHINJI NAGANAWA, and MASAHIRO YAMAZAKI. "VISUALIZATION OF BRAIN WHITE MATTER TRACTS USING HEAVILY T2-WEIGHTED THREE-DIMENSIONAL FLUID-ATTENUATED INVERSION-RECOVERY MAGNETIC RESONANCE IMAGING." Nagoya University School of Medicine, 2014. http://hdl.handle.net/2237/20547.

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16

Walker, Matthew David. "Quantitative dynamic 3D PET scanning of the body and brain using LSO tomographs." Thesis, University of Manchester, 2009. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:78135.

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17

Castelli, Filippo Maria. "3D CNN methods in biomedical image segmentation." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/18796/.

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A definite trend in Biomedical Imaging is the one towards the integration of increasingly complex interpretative layers to the pure data acquisition process. One of the most interesting and looked-forward goals in the field is the automatic segmentation of objects of interest in extensive acquisition data, target that would allow Biomedical Imaging to look beyond its use as a purely assistive tool to become a cornerstone in ambitious large-scale challenges like the extensive quantitative study of the Human Brain. In 2019 Convolutional Neural Networks represent the state of the art in Biomedic
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18

Gibert, Guillaume. "Quantification of the Cerebral Perfusion with the Arterial Spin Labelling 3D-MRI method. Quantification of the Cerebral Perfusion with the Arterial Spin Labelling 3D-MRI method." Thesis, KTH, Skolan för teknik och hälsa (STH), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-148020.

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The Arterial Spin Labelling (ASL) method is a Magnetic Resonance technique used toquantify the cerebral perfusion. It has the big advantage to be non-invasive so doesn’tneed the injection of any contrast agent. But due to a relatively low Signal-to-NoiseRatio (SNR) of the signal acquired (only approximately 1% of the image intensity), ithas been hampered to be widely used in a clinical setting so far.The primary objective of this project is to make the method more robust by improvingthe quality of the images, the SNR, and by reducing the acquisition time. DifferentASL protocols with different
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19

Dohmen, Melanie [Verfasser]. "Towards the Reconstruction of Fiber Tracts in the Human Brain by Means of 3D Polarized Light Imaging / Melanie Dohmen." Wuppertal : Universitätsbibliothek Wuppertal, 2013. http://d-nb.info/1045118958/34.

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20

Frost, Stephen Robert. "Diffusion-weighted magnetic resonance imaging with readout-segmented echo-planar imaging." Thesis, University of Oxford, 2012. https://ora.ox.ac.uk/objects/uuid:94421cdc-6bcb-49c2-b9d9-64e016b875f8.

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Diffusion-weighted (DW) magnetic resonance imaging is an important neuroimaging technique that has successful applications in diagnosis of ischemic stroke and methods based on diffusion tensor imaging (DTI). Tensor measures have been used for detecting changes in tissue microstructure and for non-invasively tracing white matter connections in vivo. The most common image acquistion strategy is to use a DW single-shot echo-planar imaging (ss-EPI) pulse sequence, which is attractive due to its robustness to motion artefacts and high imaging speed. However, this sequence has limited achievable spa
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21

Mercier, Corentin. "Geometrical modeling, simplification and visualization of brain white matter tractograms." Electronic Thesis or Diss., Institut polytechnique de Paris, 2020. http://www.theses.fr/2020IPPAT048.

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Les données de tractographie (fibres) obtenues à partir d'IRM de diffusion sont difficiles d'utilisation. Dans cette thèse, nous proposons des méthodes et algorithmes pour la simplification, la visualisation et la manipulation de ces données. Nous introduisons une représentation multi-résolution des tractogrammes, plus rapides et avec une meilleure précision géométrique que les approches de simplification existantes. Nous explorons aussi diverses représentations géométriques et nous nous concentrons sur les approches de projections aux moindres carrés (MLS) par l'intermédiaire des surfaces alg
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22

Manganas, Spyridon. "A Novel Methodology for Timely Brain Formations of 3D Spatial Information with Application to Visually Impaired Navigation." Wright State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1567452284983244.

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23

Morgan, Leah. "Development of a 3D radial MR Imaging sequence to be used for (self) navigation during the scanning of the fetal brain in utero." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22735.

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Imaging the fetal brain in utero is challenging due to the unpredictable motion of the fetus. Although ultra-fast MRI sequences are able to image a 2D slice in under a second, thus limiting the time in which fetal motion can corrupt images, Cartesian sampling makes these sequences sensitive to signal misregistration and motion-corruption. Corruption of a single 2D slice renders it impossible to reconstruct 3D volumes from these slices without complex slice-to-volume registration. There is a need for motion-robust sequences that can produce high-resolution 3D volumes of the fetal brain. The Sie
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24

Guardiola, Garcia Marta. "Multi-antenna multi-frequency microwave imaging systems for biomedical applications." Doctoral thesis, Universitat Politècnica de Catalunya, 2013. http://hdl.handle.net/10803/134967.

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Medical imaging refers to several different technologies that are used to view the human body in order to diagnose, monitor, or treat medical conditions. Each type of technology gives different information about the area of the body being studied depending on the radiation used to illuminate de body. Nowadays there are still several lesions that cannot be detected with the current methods in a curable stage of the disease. Moreover they present some drawbacks that limit its use, such as health risk, high price, patient discomfort, etc. In the last decades, active microwave imaging systems are
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25

Martin, Matthieu. "Reconstruction 3D de données échographiques du cerveau du prématuré et segmentation des ventricules cérébraux et thalami par apprentissage supervisé." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSEI118.

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Environ 15 millions d’enfants naissent prématurément chaque année dans le monde. Ces patients peuvent présenter des anomalies du développement cérébral qui peuvent causer des troubles du neuro-développement : paralysie cérébrale, surdité, cécité, retard du développement intellectuel, … Des études ont montrées que la quantification du volume des structures cérébrales est un bon indicateur qui permet de réduire ces risques et de les pronostiquer pour orienter les patients dans des parcours de soins adaptés pendant l’enfance. Cette thèse a pour objectif de montrer que l’échographie 3D pourrait êt
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Tounekti, Slimane. "Développements des méthodes d'acquisition à haute résolution spatiale en IRM de diffusion." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1008/document.

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L’IRM de diffusion (IRMd) est l’unique technique non invasive qui permet l’exploration de la microstructure cérébrale. En plus d’une large utilisation pour les applications médicales, l’IRMd est aussi utilisée en neuroscience pour comprendre l’organisation et le fonctionnement du cerveau. Toutefois, sa faible résolution spatiale et sa sensibilité aux artéfacts limitent son utilisation chez le primate non humain.L’objectif de cette étude est de développer une nouvelle approche qui permette d’acquérir des données d’IRMd à très haute résolution spatiale sur des cerveaux de macaques anesthésiés. C
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27

Habermehl, Christina Verfasser], Jens [Akademischer Betreuer] Steinbrink, Christoph [Akademischer Betreuer] Schmitz, Klaus-Robert [Akademischer Betreuer] [Müller, and Hamid [Akademischer Betreuer] Dehghani. "High-resolution 3D diffuse optical tomography for non-invasive functional brain imaging in the sub-centimeter range / Christina Habermehl. Gutachter: Klaus-Robert Müller ; Hamid Dehghani ; Jens Steinbrink. Betreuer: Jens Steinbrink ; Christoph Schmitz." Berlin : Technische Universität Berlin, 2014. http://d-nb.info/1066549095/34.

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Habermehl, Christina [Verfasser], Jens Akademischer Betreuer] Steinbrink, Christoph [Akademischer Betreuer] Schmitz, Klaus-Robert [Akademischer Betreuer] [Müller, and Hamid [Akademischer Betreuer] Dehghani. "High-resolution 3D diffuse optical tomography for non-invasive functional brain imaging in the sub-centimeter range / Christina Habermehl. Gutachter: Klaus-Robert Müller ; Hamid Dehghani ; Jens Steinbrink. Betreuer: Jens Steinbrink ; Christoph Schmitz." Berlin : Technische Universität Berlin, 2014. http://d-nb.info/1066549095/34.

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29

Murtin, Chloé Isabelle. "Traitement d’images de microscopie confocale 3D haute résolution du cerveau de la mouche Drosophile." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSEI081/document.

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La profondeur possible d’imagerie en laser-scanning microscopie est limitée non seulement par la distance de travail des lentilles de objectifs mais également par la dégradation de l’image causée par une atténuation et une diffraction de la lumière passant à travers l’échantillon. Afin d’étendre cette limite, il est possible, soit de retourner le spécimen pour enregistrer les images depuis chaque côté, or couper progressivement la partie supérieure de l’échantillon au fur et à mesure de l‘acquisition. Les différentes images prises de l’une de ces manières doivent ensuite être combinées pour gé
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30

Nazaran, Amin. "Ultra Short MR Relaxometry and Histological Image Processing for Validation of Diffusion MRI." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6348.

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Magnetic Resonance Imaging (MRI) is an imaging modality that acquires an image with little to no damage to the tissue. MRI does not introduce foreign particles or high energy radiation into the body, making it one of the least invasive medical imaging modalities. MRI can achieve excellent soft tissue contrast and is therefore useful for diagnosis of a wide variety of diseases. While there are a wide variety of available techniques for generating contrast in MRI, there are still many open areas for research. For example, many tissues in the human body exhibit such rapid signal decay that they a
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31

ARAÚJO, Caio Fernandes. "Segmentação de imagens 3D utilizando combinação de imagens 2D." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/21040.

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Submitted by Rafael Santana (rafael.silvasantana@ufpe.br) on 2017-08-30T18:18:41Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertacao Caio Fernandes Araujo Versão Biblioteca.pdf: 4719896 bytes, checksum: 223db1c4382e6f970dc2cd659978ab60 (MD5)<br>Made available in DSpace on 2017-08-30T18:18:42Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertacao Caio Fernandes Araujo Versão Biblioteca.pdf: 4719896 bytes, checksum: 223db1c4382e6f970dc2cd659978ab60 (MD5) Previous issue date: 2016-0
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Kadalie, Emile. "Development of multi-parametric human MRI at 3T." Electronic Thesis or Diss., Bordeaux, 2023. http://www.theses.fr/2023BORD0493.

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L'Imagerie par Résonance Magnétique (IRM) est une méthode de choix pour le diagnostic, le pronostic et le suivi de pathologies des tissus mous. En effet, les forts contrastes entre les tissus peuvent être modulés à la demande. Cette technique n’a jusqu’à présent montré aucune influence néfaste, permettant des examens répétitifs à haute résolution.L’IRM quantitative (IRMq) est extrêmement intéressante, car elle fournit des cartes dans lesquelles chaque pixel contient une mesure d’un paramètre physique. Contrairement aux images conventionnelles, cette quantification aide à l’interprétation objec
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Pinto, Sílvia Cristina Dias. "Análise de formas 3D usando wavelets 1D, 2D e 3D." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-02052007-085441/.

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Este trabalho apresenta novos métodos para análise de formas tridimensionais dentro do contexto de visão computacional, destacando-se o uso das transformadas wavelets 1D, 2D e 3D, as quais proporcionam uma análise multi-escala das formas estudadas. As formas analisadas se dividem em três tipos diferentes, dependendo da sua representação matemática: f(t)=(x(t),y(t),z(t)), f(x,y)=z e f(x,y,z)=w. Cada tipo de forma é analisado por um método melhor adaptado. Primeiramente, tais formas passam por uma rotina de pré-processamento e, em seguida, pela caracterização por meio da aplicação das transforma
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Abioui, Mourgues Myriam. "Dévelοppement d'un mοdèle préclinique chez la sοuris éveillée et stratégie thrοmbοlytique ciblée pοur l'AVC ischémique". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMC420.

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L’Accident Vasculaire Cérébral (AVC) ischémique, causé par l’obstruction d’une artère cérébrale, est l’une des principales causes de mortalité et d’invalidité dans le monde. Bien que des traitements comme le rtPA et la thrombectomie mécanique existent, seul un faible pourcentage de patients y a accès. Par ailleurs, malgré l’investissement de la recherche, les difficultés à transposer les résultats des modèles animaux aux essais cliniques humains limitent le développement de nouvelles thérapies. Cette thèse présente un modèle d’AVC chez la souris éveillée visant à améliorer la transposabilité d
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Bartikian, Mickael Varoujan. "3D atlas of the human brain : ex vivo magnetic resonance imaging." Master's thesis, 2020. http://hdl.handle.net/10451/48284.

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Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2020<br>Introdução: Os atlas 3D do cérebro são ferramentas essenciais na investigação em neurociências humanas, no ensino da neuroanatomia e no planeamento cirúrgico. Fornecem níveis macroscópicos/microscópicos de informação numa estrutura espacial e permitem a visualização de volumes reconstruídos a partir de dados de Ressonância Magnética (RM), bem como de estudos histológicos. A fusão das duas modalidades combina a precisão dimensional da RM com o detalhe das secções histológicas. Com a
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Lindsey, Brooks. "The Ultrasound Brain Helmet: Simultaneous Multi-transducer 3D Transcranial Ultrasound Imaging." Diss., 2012. http://hdl.handle.net/10161/6129.

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<p>In this work, I examine the problem of rapid imaging of stroke and present ultrasound-based approaches for addressing it. Specifically, this dissertation discusses aberration and attenuation due to the skull as sources of image degradation and presents a prototype system for simultaneous 3D bilateral imaging via both temporal acoustic windows. This system uses custom sparse array transducers built on flexible multilayer circuits that can be positioned for simultaneous imaging via both temporal acoustic windows, allowing for registration and fusion of multiple real-time 3D scans of cerebra
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Bouchard, Matthew Bryan. "2D and 3D high-speed multispectral optical imaging systems for in-vivo biomedical research." Thesis, 2014. https://doi.org/10.7916/D8D798G5.

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Functional optical imaging encompasses the use of optical imaging techniques to study living biological systems in their native environments. Optical imaging techniques are well-suited for functional imaging because they are minimally-invasive, use non ionizing radiation, and derive contrast from a wide range of biological molecules. Modern transgenic labeling techniques, active and inactive exogenous agents, and intrinsic sources of contrast provide specific and dynamic markers of in-vivo processes at subcellular resolution. A central challenge in building functional optical imaging systems i
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Eissa, Amir. "Investigation of gradient echo MRI for blood vessel imaging and susceptibility-weighted imaging in the human brain." Phd thesis, 2010. http://hdl.handle.net/10048/1131.

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Thesis (Ph. D.)--University of Alberta, 2010.<br>Title from pdf file main screen (viewed on July 17, 2010). A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Doctor of Philosophy, [Department of] Physics, University of Alberta. Includes bibliographical references.
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Chen, An-chia, and 陳安嘉. "Image Fusion and 3D Visualization for Head and Neck Magnetic Resonance Angiography and Brain Magnetic Resonance Imaging." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/86501586160936575238.

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碩士<br>雲林科技大學<br>工業工程與管理研究所碩士班<br>96<br>In Taiwan, there are about 13,000 people per year die from cerebrovascular diseases, the second highest cause of death. Magnetic Resonance Angiography (MRA) is one of the main tools for diagnosis of cerebrovascular diseases, which can provide a complete view of bilateral internal carotid artery and intracranial vessel. Because of the sampling constraints, MRA axial plane only presents a smaller scope of intracranial vessel imaging. Head and neck integrity of the vascular diagnostic information often need comparison with the axial and coronal plane MRA. Br
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Lindvere, Liis. "Functional Stimulation Induced Change in Cerebral Blood Volume: A Two Photon Fluorescence Microscopy Map of the 3D Microvascular Network Response." Thesis, 2011. http://hdl.handle.net/1807/31314.

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The current work investigated the stimulation induced spatial response of the cerebral microvascular network by reconstruction of the 3D microvascular morphology from in vivo two photon fluorescence microscopy (2PFM) volumes using an automated, model based tracking algorithm. In vivo 2PFM imaging of the vasculature in the forelimb representation of the primary somatosensory cortex of alpha-chloralose anesthetized rats was achieved via implantation of a closed cranial window, and intravascular injection of fluorescent dextran. The dilatory and constrictory responses of the cerebral microvascu
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