Academic literature on the topic '3807th'
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Journal articles on the topic "3807th"
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Fitriyani, Hilda, Delyuzar, and Hidayat. "Identification of CYP1A1 Gene Polymorphism in Squamous Cell Carcinoma and Cervical Adenocarcinoma." Majalah Patologi Indonesia 29, no. 2 (May 1, 2020): 65–70. http://dx.doi.org/10.55816/mpi.v29i2.410.
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BackgroundCervical cancer is the third most common cancer in women with risk factor of smoking, high parity, long term use of oralcontaception that are associated with chemical carcinogenesis. Chemical carcinogenesis require biotransfor-mation of lipophilicsubstrates to hydrophilic metabolites, therefore facilitating their secretion from the human body. Cytochrome P450 (CYP) is one ofgenes that have important role in this process. Benzo[α]pyrene and estrogen have a common biotransformation process which ismetabolized by CYP, particularly CYP1A1. The objectives to identify the frequency and distribution of CYP1A1 gene polymorphismin squamous cell carcinoma and adenocarcinoma of the cervix.MethodsThis is an analytical descriptive study with cross sectional approach. CYP1A1 gene polymorphism (3801T/C or Ile462Val) wasanalyzed using PCR-RFLP method followed by gel electrophoresis.ResultsCYP1A1 gene polymorphisms (3801TC) in squamous cell carcinoma were 50% heterozygote T/C, 36% wild-types T/T and 14%homozygote C/C. CYP1A1 gene polymorphisms (3801TC) in adenocarcinoma were 60% heterozygote T/C and 40% wild-types T/T.CYP1A1 gene polymorphisms (Ile462Val) in squamous cell carcinoma were 97.2% heterozygote Ile/Val, and 2.8% homozygoteVal/Val. CYP1A1 gene polymorphisms (Ile462Val) in adenocarcinoma were 100% heterozygote Ile/ValConclusionThe most common type of CYP1A1 gene polymorphism (3801TC and Ile462Val) in squamous cell carcinoma and adenocarcinomaof the cervix were heterozygote.
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Trombold, Charles D. "Ian Graham. Alfred Maudslay and the Maya: A Biography. 323 pp., illus., bibl., index. Norman: University of Oklahoma Press, 2002. $39.95 (cloth)." Isis 94, no. 3 (September 2003): 538–39. http://dx.doi.org/10.1086/380700.
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Matless, David. "Volker M. Welter. Biopolis: Patrick Geddes and the City of Life. 328 pp., illus., index. Cambridge Mass.: MIT Press, 2001. $39.95 (cloth)." Isis 94, no. 3 (September 2003): 539–40. http://dx.doi.org/10.1086/380701.
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Rothstein, William G. "John S. Haller, Jr. A Profile in Alternative Medicine: The Eclectic Medical College of Cincinnati, 1845–1942. xii + 212 pp., illus., app., bibl., index. Kent, Ohio/London: Kent State University Press, 1999. $35." Isis 94, no. 3 (September 2003): 540–41. http://dx.doi.org/10.1086/380702.
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Weiss, Sheila Faith, and Thomas M. Berez. "Francis R. Nicosia;, Jonathan Huener (Editors). Medicine and Medical Ethics in Nazi Germany: Origins, Practices, Legacies. viii + 160 pp., illus., table, app., bibl., index. New York/Oxford: Berghahn Books, 2002. £40, $59.95 (cloth); £13.50, $19.95 (paper)." Isis 94, no. 3 (September 2003): 541–43. http://dx.doi.org/10.1086/380703.
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Chinard, Francis P. "Jean Adrian. Louis C. Maillard: De la médecine à l’alimentation. vi + 154 pp., illus., figs., tables, app., index. Paris: Éditions Tec & Doc, 1999. Fr 350." Isis 94, no. 3 (September 2003): 543–44. http://dx.doi.org/10.1086/380704.
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Paton, Miranda. "Charles Musser. Edison Motion Pictures, 1890–1900: An Annotated Filmography. 720 pp., frontis., illus., figs., apps., bibl., indexes. Washington, D.C.: Smithsonian Institution Press, 1997. $75." Isis 94, no. 3 (September 2003): 544–45. http://dx.doi.org/10.1086/380705.
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Platt, Harold L. "Robert W. Jackson. Rails across the Mississippi: A History of the St. Louis Bridge. ix + 280 pp., illus., figs., notes, index. Champaign: University of Illinois Press, 2001. $34.95 (cloth)." Isis 94, no. 3 (September 2003): 545–46. http://dx.doi.org/10.1086/380706.
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Seidel, Robert W. "Michel Cotte. Le fonds d’archives Seguin: Aux origines de la révolution industrielle en France 1790–1860. 192 pp., illus., bibl. Privas, France: Archives Départementales de l’Ardèche, 1997." Isis 94, no. 3 (September 2003): 546–47. http://dx.doi.org/10.1086/380707.
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Oslund, Karen. "David Thomas Murphy. German Exploration of the Polar World: A History, 1870–1940. xiv + 273 pp., illus., tables, bibl., index. Lincoln/London: University of Nebraska Press, 2002. $49.95 (cloth)." Isis 94, no. 3 (September 2003): 547–49. http://dx.doi.org/10.1086/380708.
Full textDissertations / Theses on the topic "3807th"
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Bonafont, Pujol Xavier. "Variabilidad de los niveles de hemoglobina en pacientes tratados con agentes estimulantes de la eritropoyesis en pre-diálisis." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/380737.
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La variabilidad de los niveles de hemoglobina (Hb) está relacionada con la mortalidad y la morbilidad en los pacientes en hemodiálisis tratados con agentes estimulantes de la eritropoyesis (AEE). La evidencia científica sobre los efectos de la variabilidad de Hb en los pacientes en prediálisis tratados con AEE es escasa e incompleta.
OBJETIVOS: El objetivo principal de este estudio es determinar la influencia de la variabilidad de los niveles Hb con la mortalidad y la morbilidad de los pacientes. Los objetivos secundarios son: determinar la correlación de los métodos de determinación de la variabilidad (desviación estándar (DE) de Hb, desviación estándar residual (DE residual) de Hb, niveles fuera del objetivo de Hb 10-12,5g/dL), la influencia de las variables demográficas, hematológicas, bioquímicas, farmacológicas y de la comorbilidad con la variabilidad.
METODOLOGÍA: Estudio observacional prospectivo realizado en el Hospital Universitari Germans Trias i Pujol que incluyó 229 pacientes con enfermedad renal crónica tratados con AEE en prediálisis. Los criterios de exclusión fueron: pacientes con cambios de tratamiento durante 6 meses previos, estadios I y II, trasplante renal, talasemia, déficit de glucosa-6-fosfato deshidrogenasa y pacientes con menos de 3 determinaciones de Hb. El periodo de observación fue de 18 meses.
RESULTADOS: De los 229 pacientes, 109 eran mujeres (47,6%), con una edad media de 70,44 años (25-94) y un IMC de 28,29Kg/m2 (16,40-46,86).El 34% tenía un estadio III, el 52% estadio IV y el 14% estadio V. Veintitrés pacientes se trataron con eritropoyetina beta,149 con darbepoetina alfa y 57 con CERA. Solo el 24% y el 29,3% de los pacientes mantuvieron 4 ó 3 determinaciones de Hb en el objetivo. Los métodos para determinar la variabilidad se correlacionaron entre sí (p=0,000). No se pudo demostrar su influencia sobre la mortalidad (p=0,569). Se obtuvo un incremento de los índices de hospitalización (p=0,05) y del número de días de estancia (5 días aproximadamente). El deterioro de la función renal también fue mayor en los pacientes con mayor variabilidad (p=0,05). Los niveles séricos de calcio DE, urato DE, fibrinógeno, albúmina y ferritina se relacionaron con la variabilidad (p≤0,05). El intervalo prolongado de administración de los AEE se relacionó con una menor variabilidad (p=0,001). La administración concomitante de IECA, antirretrovirales y citostáticos aumentó la variabilidad (p≤0,05). Solo la enfermedad cerebro vascular, las hemorragias y las transfusiones afectaron la variabilidad (p≤0,05).
CONCLUSIONES: La variabilidad de Hb aumenta la morbilidad de los pacientes tratados con AEE en prediálisis (hospitalización y deterioro renal). La pauta de los AEE y cierta medicación concomitante puede afectar la variabilidad de los niveles de Hb.Hemoglobin (Hb) variability is related with mortality and morbidity in hemodialysis patients treated with erythropoietic agents (EA). Evidence of possible effects of Hb variability in pre-dialysis patients is scarce and incomplete. Objectives: The primary endpoint of this study is to determine the influence of Hb variability with mortality and morbidity of patients. Secondary endpoints are to determine the correlation of methods used to determine Hb variability (Hb standard deviation (SD), Hb residual SD, Hb levels out target 10-12,5g/dL) and the influence of demographic, biochemistry, hematological, and pharmacological variables and co morbidities over Hb variability. Methods: This observational and prospective study carried out in University Hospital Germans Trias i Pujol (Badalona, Spain) included 229 chronic kidney disease (CKD) patients treated with EA in pre-dialysis. Exclusion criteria were: patients with any change in EA treatment during previous 6 months, CKD stages I and II, renal transplantation, thalassemia, glucose-6-phosphate dehydrogenase deficiency, and patients with less than 3 Hb determinations. Observation period was 18 months. Results: Out 229, 109 (47,6%) were females, with 70.44 years of median age (range 25-94),median BMI of 28.29 kg/m2(range 16.40-46.86), with 34% , 52% and 14% of CKD stages III, IV and V respectively.23 patients were treated with EPO beta, 149 with darbepoetina alpha and 57 with CERA. Only 24% and 29.3% of patients achieved 4 or 3 Hb determinations on target (10-12,5g/dL). Methods for Hb variability determination were correlated (p=0.000). No Hb variability correlation with mortality were found (p=0.569. An increase of hospitalization rate was obtained (p=0.05) and with a longer inpatient stay (5 days). Also renal function decline was higher in patients with high Hb variability (p=0.05). Plasma levels of calcium SD, urate SD, fibrinogen, albumin and ferritin were correlated with Hb variability (p≤0.05). More prolonged EA administration were related with less Hb variability ( p=0.001) and concomitant administration of ACEI, antiretrovirals and cytostatics increase Hb variability (p≤0.05). Only cerebral vascular disease, bleeding and transfusions were affected Hb variability (p≤0.05). Conclusions: In pre-dyalisis EA treated patients, high Hb variability increase morbidity (hospitalization and renal function decline). Therapeutic regime of EA and concomitant medication as ACEI, antiretrovirals and cytostatics may affect Hb variability.
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Torrens, Armengol Antonina. "Subsurface flow constructed wetlands for the treatment of wastewater from different sources. Design and operation." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/380738.
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The aim of the thesis is to examine the viability of the subsurface constructed wetlands for the treatment of wastewater derived from three different sources (treatment ponds, pig farms and car wash facilities), and to evaluate the influence of design (size, type and depth of media, presence of Phragmites australis) and operational parameters (hydraulic load, dosing and feeding modes) on treatment efficiency and hydraulic behavior.
Several studies were done in the framework of different national and European R+D projects in 4 study sites. The viability of constructed wetlands with vertical and/or horizontal subsurface flow to treat the effluent from wastewater treatment pond systems (facultative and tertiary ponds) for discharge or reuse was evaluated in two municipal wastewater treatment plants, one in Aurignac (France) and the other in Santa Eugènia (Mallorca, Spain). The evaluation of the viability of hybrid subsurface flow constructed wetlands to treat swine slurry for land application or discharge in water bodies was performed in small farm was Can Corominas located in Viver i Serrateix (Barcelona, Spain). Finally, the viability of vertical and horizontal flow constructed wetlands to treat the effluent from car wash facilities for recycling was evaluated at a car wash station located in Montfullà (Girona, Spain), using an infiltration-percolation system as reference. A monitoring of the water quality (physicochemical and microbiological parameters) and the filters’ hydraulic (monitoring of flows, infiltration rates and tracer tests experiments) were performed.
The main outcome of the thesis is the viability of the application of different configurations of subsurface flow constructed wetlands to treat the effluents from a wastewater treatment pond, a pig farm, and a car wash facility, once design and operation have been optimized. Subsurface flow constructed wetlands have shown resilience to load and hydraulic fluctuations, to new pollutants and to variable environmental conditions; being simple to operate and maintain with null or minimum energy requirements and with an added aesthetical value.
From the case studies several points can be indicated as main conclusions. Paying special attention to the pond effluent study, it was characterised by a large quantity of algae and a high effluent variability that mainly depends temperature and solar irradiation. The experimental results demonstrated the effectiveness of vertical and horizontal flow constructed wetlands to upgrade pond effluent quality by retaining algae and suspended solids, completing organic matter degradation, and nitrifying the pond effluent in the case of vertical flow and partially removing total nitrogen in the case of horizontal flow. The filtering media size (sand or gravel) was the key parameter for algae retention. The presence of plants did not significantly affect the filter performance. The filtering media size (sand or gravel) was the key parameter for algae retention. The removal of microbial indicators depended mainly on the water retention time in the filter, which in turn depended on the media granulometry and hydraulic load, and on the depth of the filter and the dose volume per batch.
The swine slurry presented high concentrations of suspended solids, organic matter, nitrogen and phosphorous, with high variability depending. The high ammonia contents interfered with the growth of Phragmites australis, while the high concentration of suspended solids and organic matter also limited the type of subsurface flow constructed wetland to be implemented. The hybrid configuration, which combines vertical and horizontal flow constructed wetlands, had a dual function for simultaneous solid-liquid separation and biological treatment. Removal of organic matter and suspended solids was very high, while the overall nitrogen load removal was around 65%, due to the combined nitrification/denitrification processes. The maximum number of feeding days was a key factor to avoid clogging. Some of the contaminants were retained and mineralised in the surface deposit layer of the vertical flow filter, increasing around 20 cm each year.
Finally, car wash effluent had a high concentration of inorganic suspended solids, very variable concentrations of E. coli and organic matter, low concentrations of nutrients, and the presence of hydrocarbons, fats and oils and non-ionic surfactants. The three technologies evaluated performed very efficiently with respect to turbidity, organic material, and suspended solids. Non-ionic detergents, hydrocarbons, fats and oils were also completely removed, but their concentrations in the influent were already very low. E. coli was also removed to acceptable limits for recycling, with concentrations lower than the limits established in the Royal Decree guidelines for reuse in Spain. The oil and fats contents of the car wash effluents as well as the inorganic suspended solids made pre-treatment necessary in order to avoid media clogging. The low concentrations of nutrients resulted in a slow growth of Phragmites australis especially in horizontal flow constructed wetlands.L'objectiu principal de la tesi és l’estudi de la viabilitat dels aiguamolls construïts amb flux subsuperficial per al tractament d'aigües residuals de diferents orígens (llacunatges, granges de porcs i instal·lacions de rentat de cotxes), i avaluar la influència dels paràmetres de disseny i d’operació en l'eficiència del tractament i el comportament hidràulic. Els estudis experimentals es van realitzar en el marc de diversos projectes de R+D+I nacionals i europeus R+D+I. La viabilitat dels aiguamolls construïts amb flux subsuperficial vertical i/o horitzontal per al tractament dels efluents de sistemes de llacunatges (facultatiu i terciari) es va avaluar en dues plantes de tractament d'aigües residuals urbanes, a Aurignac (França) i a Santa Eugènia (Mallorca, Espanya). Per al tractament de purins es va construir una planta pilot d'aiguamolls de tipus híbrid en una granja situada a Viver i Serrateix (Barcelona, Espanya). Finalment, es va realitzar un estudi de la viabilitat dels aiguamolls construïts de flux vertical i horitzontal per al tractament i reciclatge dels efluents d’instal·lacions de rentat de cotxes en una estació situada a Montfullà (Girona, Espanya), utilitzant un sistema d'infiltració-percolació com a referència. Es va fer el seguiment de la qualitat de l'aigua (paràmetres fisicoquímics i microbiològics) i de la hidràulica d’aquestes tecnologies (control de cabals, velocitats d'infiltració i experiments amb traçadors). La principal conclusió de la tesi és que l'aplicació de diferents configuracions d’aiguamolls construïts de flux subsuperficial per tractar els tres tipus d’aigües residuals estudiades és viable, malgrat que se n'ha d'optimitzar el disseny i l’operació. S'ha constatat que els aiguamolls construïts de flux subsuperficial vertical i horitzontal milloren la qualitat dels efluents de llacunatges, mitjançant la retenció de les algues i dels sòlids suspesos i completant la degradació de la matèria orgànica. La granulometria del medi filtrant és un paràmetre clau per a la retenció d'algues. L'eliminació dels indicadors microbiològics depèn principalment del temps de retenció d'hidràulica, que depèn, alhora, de la granulometria dels filtres, de la profunditat del medi, de la càrrega hidràulica i del fraccionament d’aquesta. Per altra banda, la configuració híbrida d'aiguamolls construïts, que combina flux vertical i horitzontal, presenta uns elevats rendiments d'eliminació de matèria orgànica i sòlids en suspensió dels purins. El nitrogen s'elimina al voltant del 65% gràcies als processos combinats de nitrificació (al filtre vertical) i desnitrificació (a l'horitzontal). L’elevada concentració d'amoníac dels purins va interferir en el creixement de Phragmites australis. Alguns dels contaminants van ser retinguts i mineralitzats i van formar una capa a la superfície del filtre de flux vertical. Aquesta capa ajuda a la depuració augmentant la filtració i els temps de retenció hidràulica, però cal limitar-ne el creixement mitjançant el control de la càrrega orgànica i dels períodes de descans per tal que no es produeixi una disminució massa gran de la infiltració. Finalment, les tres tecnologies avaluades per tractar els efluents de rentat de cotxes van resultar molt eficients pel que fa a la reducció de la terbolesa, de la matèria orgànica i dels sòlids suspesos. Els detergents no iònics, els hidrocarburs, els greixos i els olis també es van eliminar completament, però les seves concentracions en l'influent eren molt baixes. L’eliminació d’E. coli també va resultar elevada, especialment al sistema d’infiltració-percolació i a l'aiguamoll construït de flux vertical, de manera que es van assolir límits de qualitat aptes per al reciclatge. Les baixes concentracions de nutrients van donar com a resultat un creixement lent de Phragmites australis. El contingut d'oli i de greixos d’aquests efluents, així com els sòlids inorgànics en suspensió, fan necessari un pretractament.
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San, Lucas Ceballos Malka Andrea. "Los derechos de los pueblos indígenas ante la explotación petrolera del Yasuní-ITT." Doctoral thesis, Universitat Rovira i Virgili, 2015. http://hdl.handle.net/10803/380742.
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El Yasuní, és l'àrea protegida més gran de l'Equador continental i una de les zones de major diversitat genètica del planeta. A més, és la llar de diversos pobles indígenes, entre ells pobles en aïllament voluntari. Així mateix, és un espai sotmès a l'extracció petroliera ja que se situa en una zona estratègica per l'Equador en matèria energètica. L'Estat, en el seu afany de satisfer la necessitat energètica i sostenir les finances i l'economia nacional, promou l'aprofitament de recursos naturals no renovables com el petroli, la qual cosa ha implicat no solament degradacions ambientals en tot el país, sinó també afectacions directes als drets dels pobles indígenes, per la coincidència de zones mega diverses i territoris indígenes amb les instal•lacions petrolieres.
En aquest context, el 2007 va sorgir la Iniciativa Yasuní-ITT, que buscava, entre altres objectius, respectar el territori de les comunitats indígenes que viuen al Yasuní abstenint-se d’explotar les reserves petrolieres del bloc ITT per temps indefinit. No obstant això, aquesta Iniciativa va finalitzar el 2013 al no complir-se amb els objectius econòmics previstos per tal què la seva execució fos viable.
La present tesi explora la relació existent a l’Equador entre explotació petroliera i drets dels pobles indígenes, concretament al Yasuní i més específicament davant la decisió d'explotació del bloc ITT. Mitjançant l'estudi del marc jurídic nacional i internacional dels drets dels pobles indígenes es busca determinar la seva situació jurídica per així establir si l'explotació del ITT posa en risc la seva supervivència física i cultural o interfereix amb els seus drets, tals com el dret a la propietat, a la participació, a la consulta i els drets específics dels pobles en aïllament voluntari. A més de considerar de manera general les implicacions per a la resta dels equatorians.El Yasuní es el área protegida más grande del Ecuador continental y una de las zonas de mayor diversidad genética del planeta. Además, es el hogar de varios pueblos indígenas, entre ellos, pueblos en aislamiento voluntario. Asimismo, es un espacio sometido a la extracción petrolera por encontrarse ubicado en una zona estratégica para el Ecuador en materia energética. El Estado en su afán de satisfacer la necesidad energética y sostener las finanzas y la economía nacional, promueve el aprovechamiento de recursos naturales no renovables como el petróleo, lo que ha implicado no solo degradaciones ambientales en todo el país sino también afectaciones directas a los derechos de los pueblos indígenas, por la coincidencia de zonas mega diversas y territorios indígenas con las instalaciones petroleras. En este contexto surgió en 2007 la Iniciativa Yasuní-ITT, que buscaba entre otros objetivos, respetar el territorio de las comunidades indígenas que viven en el Yasuní mediante la abstención de explotación de las reservas petroleras del bloque ITT por tiempo indefinido. No obstante, dicha Iniciativa finalizó en 2013 al no cumplirse con los objetivos económicos previstos para que su ejecución fuera viable. La presente tesis explora la relación existente en Ecuador entre explotación petrolera y derechos de los pueblos indígenas, concretamente en el Yasuní y más específicamente ante la decisión de explotación del bloque ITT. Mediante el estudio del marco jurídico nacional e internacional de los derechos de los pueblos indígenas se busca determinar su situación jurídica para así establecer si la explotación del ITT pone en riesgo su supervivencia física y cultural o interfiere con sus derechos, tales como el derecho a la propiedad, a la participación, a la consulta y los derechos específicos de los pueblos en aislamiento voluntario. Además de considerar de manera general las implicaciones para el resto de los ecuatorianos también.
Yasuní is the largest protected area of continental Ecuador and one of the world’s greatest genetically diverse areas. It is also home to several indigenous peoples, including those in voluntary isolation. At the same time it is an area subject to oil extraction since it is located in a zone considered strategic for Ecuador’s energy sector. On its effort to meet its energy needs and sustaining its finances and the country’s economy, the State encourages the use of the non-renewable natural resources such as oil, situation that has led not only to environmental degradation all over the country but has also had effects on the rights of indigenous populations, as mega diverse areas and indigenous territories often coincide with oil extraction facilities. It is within this context that in 2007 the Yasuní-ITT Initiative was launched. Among others, one of the objectives of the Initiative was to respect the territories of the indigenous communities that inhabit the Yasuní by leaving the oil reserves in the ITT oil block underground indefinitely. Nevertheless, this Initiative was abandoned in 2013 after not meeting the established economic goals required for its implementation to be feasible. This thesis explores the relationship between oil exploitation and indigenous peoples’ rights in Ecuador, particularly in the Yasuní and more specifically in relation with the decision of exploiting the ITT oil block. By studying the international and national legal frameworks of the rights of indigenous peoples we intend to determine their legal status in order to establish whether the ITT exploitation jeopardizes their physical and cultural survival or interferes with their rights, such as property right, the right to participate, to be consulted and the specific rights of peoples in voluntary isolation. Plus, we will also take into account the general implications for the rest of the Ecuadorians.
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Ng, Choi I.-teng Montserrat. "Solid-phase synthesis of 5-arylhistidine-containing peptides: from linear antimicrobial peptides to cyclic peptides derived from arylomycins and aciculitins." Doctoral thesis, Universitat de Girona, 2015. http://hdl.handle.net/10803/380739.
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The incorporation of unsymmetrical biaryl systems into peptide sequences is a strategy that can improve their biological activity. Due to the difficulty of arylating the 4(5}-position of the imidazole ring, this doctoral thesis was focused on the development of efficient methodologies for the solid-phase synthesis of 5-arylhistidine-containing antimicrobial undecapeptides through a Suzuki-Miyaura reaction under microwave irradiation. The extension of this protocol allowed the preparation of biaryl cyclic peptides of different ring sizes bearing a His-Phe or His-Tyr biaryl linkage. Then, it was developed a procedure for the total solid-phase synthesis of biaryl cyclic lipopeptides derived from arylomycins. These strategies were extended to the preparation of biaryl cyclic analogues of the marine bicyclic pptides aciculitins. In particular, it was achieved the synthesis of analogues of the northern and the southern hemispheres of aciculitins as well as biaryl bicyclic peptides incorporating a Phe-Phe, a Phe-Tyr, a His-Tyr or a Tyr-Tyr biaryl bridgeLa incorporació de sistemes biarílics asimiètrics en seqüències peptídiques es considera un enfocament útil per a millorar l'activitat biològica de pèptids. Tenint en compte la dificultat d'arilar la posició 4 (5) de l'anell d'imidazole, aquesta tesi doctoral es centra en el desenvolupament de noves estratègies eficients per a la preparació en fase sòlida d'undecapèptids antimicrobians contenint una 5-arilhistidina a través d'una reacció de Suzuki-Miyaura sota irradiació microones. L'extensió d'aquesta metodologia ha permès la síntesi de pèptids biarílics cíclics de diferents mides que incorporen un enllaç His-Phe 0 His-Tyr. Posteriorment, s'ha desenvolupat un procediment per la síntesi total en fase sòlida de lipopèptids biarílics cíclics derivats de les arilomicines. Les estratègies anteriors s'han estès a la preparació de compostos biarílics anàlegs dels pèptids bicíclics marins aciculitines. Concretament, s'ha preparat anàlegs dels hemisferis nord i sud de las aciculitines així com pèptids biarílics bicíclics que incorporen un pont Phe-Phe, Phe-Tyr, Tyr-His 0 Tyr-Tyr.
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Horra, Pueyo Alfons. "Evidències en teixit adipós d'alteracions gèniques dels vasos limfàtics en l'obesitat." Doctoral thesis, Universitat Rovira i Virgili, 2016. http://hdl.handle.net/10803/380741.
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L’obesitat es caracteritza per una excessiva acumulació de teixit adipós, tant en els seus dipòsits subcutanis com viscerals. Esdeveniments sistèmics i locals tenen lloc en aquesta morbiditat. El drenatge intersticial per part dels vasos limfàtics és una de les modificacions estructurals, que, fins ara, ha estat escassament considerada.
En el nostre estudi hem analitzat l’expressió en teixit adipós de diversos gens relacionats amb la formació dels vasos limfàtics de diferents maneres, per mitjà de l'anàlisi de microarrays i estudis d'expressió gènica RT PCR en diverses cohorts, incloent prims, obesos i pacients amb resistència a la insulina i diabetis mellitus tipus 2. Hem plantejat la hipòtesi que hi hagi diferències associables a les disfuncions metabòliques valorades.
L’anàlisi dels dos gens implicats en l’estructuració dels vasos limfàtics; prox1 i pdpn, ens permet establir un vincle indirecte entre l'obesitat i les modificacions de l'expressió gènica del teixit adipós, tant en l’àmbit subcutani com visceral.
Una major expressió d'ARNm d'ambdós gens s'observa en el teixit adipós visceral en totes les condicions metabòliques estudiades. De la mateixa manera, es descriu una sèrie d'associacions amb variables clíniques, analítiques i d’expressió gènica per part d’aquests dos gens seleccionats, sent el mRNA d’atg7 (autophagy related 7) i d’atg3 (autophagy related 3) els principals determinants de l’expressió de prox1 i pdpn, respectivament.
Arribem a la conclusió que l’alteració hidrodinàmic del interstici podria ser considerada potencialment com un nou element a tenir en compte en el teixit adipós, principalment en les persones obeses. Nous estudis, mecanicistes, estan garantits.La obesidad se caracteriza por una excesiva acumulación de tejido adiposo, tanto a nivel de la localización subcutánea como visceral. Se han descrito alteraciones tanto sistémicas como locales en esta morbilidad. El drenaje intersticial por parte de los vasos linfáticos es una de las modificaciones estructurales, que hasta el momento ha sido escasamente considerada. En nuestro estudio se han analizado la expresión en tejido adiposo de diversos genes relacionados con la formación de los vasos linfáticos utilizando diversas estrategias, mediante análisis de expresión utilizando microarrays y por estudios de expresión génica RT-PCR en diversas cohortes, incluyendo delgados, obesos i pacientes con resistencia a la insulina y diabetes mellitus. Hemos planteado la hipótesis de que existan diferencias asociadas a las alteraciones metabólicas valoradas. El análisis de los dos genes implicados en la estructuración de los vasos linfáticos; prox1 y pdpn, nos ha permitido establecer vínculos indirectos entre la obesidad y las modificaciones de la expresión génica del tejido adiposo, tanto a nivel subcutáneo como visceral. Una mayor expresión de ARNm de ambos genes se observa en el tejido adiposo visceral en todas las condiciones metabólicas estudiadas. De la misma manera, se describen una serie de asociaciones con variables clínicas, analíticas y de expresión génica por parte de estos dos genes seleccionados, siendo el ARNm de atg7 (autophagy related 7) y de atg3 (autophagy related 3) los principales determinantes de la expresión de prox1 i pdpn respectivamente. Concluimos que la alteración hidrodinámica del intersticio podría ser considerada, potencialmente, como un nuevo elemento a considerar en el tejido adiposo, principalmente en las personas obesas. Nuevos estudios relacionados con los mecanismos de dichas alteraciones serán necesarios en el futuro.
Obesity is characterized by an excessive adipose tissue accumulation both in subcutaneous and visceral depots. Systemic and local events, take part in this morbidity. Interstitial drainage by lymphatic vessel in adipose tissue is one of the structural modifications, that has been scarcely considered up to now. In our study we have screened adipose tissue expression of several genes linked with lymphatic vessels in different ways, by means of microarray analyses and RT PCR gene expression studies in several cohorts, including lean, obese and patients with insulin resistance and type 2 diabetes mellitus. We have hypothesized that differences could be found considering the diverse metabolic dysfunctions mentioned above. Joined analysis of the two main genes involved in the lymphatic context; prox1 and pdpn, allows us to establish an indirect link between obesity and modifications of the adipose tissue gene expression, both in subcutaneous and visceral fat. A higher mRNA expression of both genes, is observed in visceral fat in all of the studied metabolic conditions. Likewise, we describe a number of associations with clinical, analytical and gene expression variables regarding these two selected genes, being the autophagy related 7 (atg7) and autophagy related 3 (atg3) mRNA gene expression the main determinants of prox1 and pdn expression in adipose tissue, respectively. We conclude that hydrodynamic dysfunction could be considered as a new potential player in adipose tissue mainly in obese people. New mechanistic studies are guaranteed.
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Dimitriadis, Caterina. "Towards the implementation of ecosystem management: a multi-level assessment of a small scale Mediterranean multi-specific fishery." Doctoral thesis, Universitat de Girona, 2015. http://hdl.handle.net/10803/380743.
Full textAbstract:
Fisheries are complex systems, in which the process of assessment and management should explicitly consider the ecological, social and economic attributes of the system. For a responsible and sustainable management of marine resources and their interaction with the fishing activity, both, managers and scientists, are necessary. The multidimensional view of the Ecosystem Approach to Fisheries Management (EAFM:) provides the most suitable context for managing small-scale fisheries, promoting-the participation of all members of society linked to the fishing activity, as co-management is a key factor in their development. In Catalonia, the fishermen guild of the port of Palam6s is one of the most important in the region of Baix Emporda and holds ample historical record of local fishing activity information. This PhD dissertation applies the information from the fishermen guild of the port of Palam6s, through a vision of EAFM:, considering fisheries as a socio-economic unit (systemic approach), but also as different ecosystem components representing different levels of the hierarchy on the biological organization (communities and individual species). From a systemic context, the use of the Living Planet Index (LPI) is proposed to describe the fishe:r:y dynamics in order to assess the performance of the fishery targeted by the fishermen guild of Palam6s, analyzing simultaneously the degree of compliance with the objectives of the Aichi Biodiversity Targets. The LPI index is suitable for multi-specific fisheries using different fishing strategies as the smallscale fisheries of the Palam6s port. At the level of the biological communities and through a network approach, potential management units were identified based on the analysis of by-catch, thus incorporating non-target species. According to the characteristics of each module, at least some of these could be considered management units not evident using a different approach. Finally, the effects of SSF were evaluated on a commercial interest species, Pagellus erythrinus. In that sense, it has been re-evaluated the reproductive cycle by means of an histological approach, various population parameters were estimated and the vulnerability of this species in relation to the activities of SSF was evaluated, in an attempt to show a practical application of the third hierarchical management level, that must be considered in an ecosystem approach to fisheries on the biological strategy of the species, since species individually, respond differently to different types of fishing pressure and any management carried out considering all the species as a whole, would probably fail.Les pesqueres constitueixen sistemes complexos, en el quals el procés d'avaluació i gestió hauria de considerar explícitament els atributs ecològics, socials i econòmics del sistema. Per aconseguir una gestió responsable i sostenible del recursos marins és necessària la interacció de pescadors, gestors i científics. La visió multi-dimensional de l'Enfocament Ecosistémic de la Pesca (EEP) proporciona el context general més adequat per a la gestió de pesqueres a petita escala. El EEP promou la participació de tots els membres de la sacietat relacionats amb l'activitat pesquera, i per tant la cogestió és un element clau per al seu desenvolupament. A Catalunya, la Confraria del port de Palamós és una de les més importants de la regió del Baix Empordà i compta amb un ampli registre històric d' informació pesquera local. En aquesta tesi s'avalua com maximitzar l'ús de la informació provinent de la Confraria del part de Palamós, a través d'una visió d' EEP considerant a la pesquera com una unitat socioeconòmica (enfocament sistèmic) però també considerant els diferents components de l'ecosistema, representant diferents nivells de la jerarquia de l'organització biològica (com u ni ta ts i espècies individuals). En un context sistèmic, es proposa l'ús de l'Índex Planeta Viu (LPI per les seves sigles en anglès) per descriure la dinàmica pesquera, de Palamós, simultàniament analitzant el grau d'acompliment dels objectius d'Aichi Biodiversitat. Aquest índex, és adequat per pesqueres multi-específiques que fan servir diverses estratègies de pesca, com és el cas la pesca artesanal de Palamós. A nivell de comunitats biològiques, i través d'un enfocament de xarxes es van identificar possibles unitats de gestió, partint de l'anàlisi del descart, i incorporant d'aquesta manera les espècies no objectiu. D'acord a les característiques de cada mòdul, alguns podrien ser considerats com a unitats de gestió, fins ara no evidents com a tals eines de gestió. Finalment es van avaluar els efectes de la pesca a petita escala sobre una espècie d'interès comercial, Pagellus erythrinus. En aquest sentit, es va revaluar el cicle reproductiu a través d'una anàlisi histològica, es van estimar diversos paràmetres poblacionals i es va avaluar la vulnerabilitat d'aquesta espècie en relació a les activitats de la pesca artesanal. Aquest exemple pretén demostrar que l'estratègia biològica de l'espècie, és el tercer nivell jeràrquic que cal tenir present en un enfoc ecosistèmic de la pesca, atès que les espècies, individualment, responen de manera diferent als diferents tipus de pesca i a la pressió, i qualsevol gestió que es van estimar diversos paràmetres poblacionals i es va avaluar la vulnerabilitat d'aquesta espècie en relació a les activitats de la pesca artesanal. Aquest exemple pretén demostrar que l'estratègia biològica de l'espècie, és el tercer nivell jeràrquic que cal tenir present en un enfoc ecosistèmic de la pesca, atès que les espècies, individualment, responen de manera diferent als diferents tipus de pesca i a la pressió, i qualsevol gestió que es dugui a terme considerant les espècies com un conjunt, fracassarà.
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Monné, Alexandra. "Factors psicosocials implicats en la construcció de la identitat nacional: un estudi empíric en el context del Principat d'Andorra." Doctoral thesis, Universitat de Girona, 2015. http://hdl.handle.net/10803/380744.
Full textAbstract:
This thesis examines national identity in order to understand the psychological mechanisms underlying social and cultural nature of its
construction. The study presented here aims to describe in greater detail and depth as knowledge and attitudes, the curriculum and language, among other factors relate to national identities and attitudes. The empirical study takes place in the context of the Principality of Andorra where coexist several languages besides characterized by having different educational styles. National identity,, like many other identities depends on the context in which it is expressed and experienced and that is why we think that should be treated from a psychosocial perspective. Analysis and understanding of the factors involved in the construction of national identity, can help to clarify the nature of psychological theories and social challenges face greater guarantees of capital importance such as the maintenance of social cohesion.En aquesta tesi s'analitza la identitat nacional amb l'objectiu de comprendre'n els mecanismes psicològics de naturalesa social i cultural subjacents a la seva construcció. L'estudi té l'objectiu de descriure amb major deta.11 i profunditat com el coneixement i les actituds, el currículum escolar i la llengua, entre altres factors, es relacionen amb les identificacions i actituds nacionals. L'estudi empíric té lloc en el context del' Principat d'Andorra on hi.conviuen diferents llengües, a més de caracteritzar-se per disposar de diferents estils educatius. La identitat nacional, com moltes altres identitats, depèn del context en què s'expressa i s'experimenta i és per això, pensem, que s'ha de tractar des d'una perspectiva psicosocial. L'anàlisi i comprensió dels factors implicats en la construcció de la identitat nacional pot contribuir a aclarir la naturalesa de teories psicològiques, així com afrontar amb majors garanties reptes socials de capital importància com són el manteniment de la cohesió social.
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Pino, León Manuel. "Anamorfosis y artificios perspectivos en la Península Ibérica entre los siglos XVI y XVIII." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/380740.
Full textAbstract:
Con el nombre “anamorfosis” se conoce un artificio perspectivo, pensado para ser contemplado desde un lugar concreto, que da la impresión de presentar una imagen real pero que en realidad no existe como tal, sino que es una especie de ilusión óptica. Utilizado actualmente como curiosidad o reclamo publicitario en algunos recintos al aire libre (estadios de fútbol, canchas de baloncesto), este juego óptico es tan antiguo como la propia perspectiva. Se relaciona con otros como la cuadratura, arquitecturas pintadas en trampantojo que parecen continuar el espacio real al ser vistas desde cierto lugar; también la escenografía teatral barroca utilizaría esta clase de recursos ilusionistas. Cuando el punto de vista es el correcto, estas imágenes son tan reales que parecen flotar en el espacio y crean la duda sobre lo que es real o lo que es pintado.
El estudio de las anamorfosis es un tema arriesgado, pues esa espectacularidad puede hacer que un trabajo como éste se quede en la superficie, deslumbrado por la vistosidad del asunto. Lo que nos proponemos aquí no es tanto hacer un muestrario de curiosidades visuales como explorar el papel que este tipo de artificios tuvo ya desde el mismo origen de la perspectiva cónica, a principios del siglo XV.
Para ello empezaremos con un apartado de contextualización, en el que se intentará hacer un catálogo de la mayoría de los autores europeos que plantearon estas cuestiones. Además se incluyen referencias extraídas de textos sobre teoría del arte y la literatura, que nos aportarán pistas sobre el trasfondo social, cultural, científico, artístico y filosófico en el que se produjeron en estas obras. Para finalizar este bloque inicial, incluiremos un resumen sistemático de las posibles clasificaciones de las anamorfosis, tanto por lo que hace a su método de trazado como por la temática.
El segundo bloque, que es el fundamental de la tesis, analiza los textos de los siglos XVI al XVIII, escritos en castellano o portugués, que tratan de lo que hoy en día conocemos como anamorfosis o de cuadratura. Entre ellos se incluyen tratados de pintura, arquitectura o matemáticas, aunque también se han estudiados algunas cartillas de dibujo y un cuaderno de artista (el “Cuaderno italiano” de Goya).
Finalmente, se ha incluido un apartado sobre referencias a la anamorfosis en fuentes literarias. Aunque se nos había planteado la duda de hasta qué punto tenía sentido incluir aquí estos contenidos, pero las menciones literarias (novelas, obras teatrales o poemas) no dejan de ser referencias escritas que aportan información sobre el aspecto, origen, difusión e intencionalidad que este tipo de artificio tuvieron durante el periodo que nos interesa.
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Bonafont, Pujol Xavier. "Variabilitat dels nivells d’hemoglobina en pacients tractats amb agents estimulants de l’eritropoesi en pre-diàlisi." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/380737.
Full textAbstract:
Amb la participació de l'Hospital Germans Tries i PujolLa variabilidad de los niveles de hemoglobina (Hb) está relacionada con la mortalidad y la morbilidad en los pacientes en hemodiálisis tratados con agentes estimulantes de la eritropoyesis (AEE). La evidencia científica sobre los efectos de la variabilidad de Hb en los pacientes en prediálisis tratados con AEE es escasa e incompleta. OBJETIVOS: El objetivo principal de este estudio es determinar la influencia de la variabilidad de los niveles Hb con la mortalidad y la morbilidad de los pacientes. Los objetivos secundarios son: determinar la correlación de los métodos de determinación de la variabilidad (desviación estándar (DE) de Hb, desviación estándar residual (DE residual) de Hb, niveles fuera del objetivo de Hb 10-12,5g/dL), la influencia de las variables demográficas, hematológicas, bioquímicas, farmacológicas y de la comorbilidad con la variabilidad. METODOLOGÍA: Estudio observacional prospectivo realizado en el Hospital Universitari Germans Trias i Pujol que incluyó 229 pacientes con enfermedad renal crónica tratados con AEE en prediálisis. Los criterios de exclusión fueron: pacientes con cambios de tratamiento durante 6 meses previos, estadios I y II, trasplante renal, talasemia, déficit de glucosa-6-fosfato deshidrogenasa y pacientes con menos de 3 determinaciones de Hb. El periodo de observación fue de 18 meses. RESULTADOS: De los 229 pacientes, 109 eran mujeres (47,6%), con una edad media de 70,44 años (25-94) y un IMC de 28,29Kg/m2 (16,40-46,86).El 34% tenía un estadio III, el 52% estadio IV y el 14% estadio V. Veintitrés pacientes se trataron con eritropoyetina beta,149 con darbepoetina alfa y 57 con CERA. Solo el 24% y el 29,3% de los pacientes mantuvieron 4 ó 3 determinaciones de Hb en el objetivo. Los métodos para determinar la variabilidad se correlacionaron entre sí (p=0,000). No se pudo demostrar su influencia sobre la mortalidad (p=0,569). Se obtuvo un incremento de los índices de hospitalización (p=0,05) y del número de días de estancia (5 días aproximadamente). El deterioro de la función renal también fue mayor en los pacientes con mayor variabilidad (p=0,05). Los niveles séricos de calcio DE, urato DE, fibrinógeno, albúmina y ferritina se relacionaron con la variabilidad (p≤0,05). El intervalo prolongado de administración de los AEE se relacionó con una menor variabilidad (p=0,001). La administración concomitante de IECA, antirretrovirales y citostáticos aumentó la variabilidad (p≤0,05). Solo la enfermedad cerebro vascular, las hemorragias y las transfusiones afectaron la variabilidad (p≤0,05). CONCLUSIONES: La variabilidad de Hb aumenta la morbilidad de los pacientes tratados con AEE en prediálisis (hospitalización y deterioro renal). La pauta de los AEE y cierta medicación concomitante puede afectar la variabilidad de los niveles de Hb.
Hemoglobin (Hb) variability is related with mortality and morbidity in hemodialysis patients treated with erythropoietic agents (EA). Evidence of possible effects of Hb variability in pre-dialysis patients is scarce and incomplete. Objectives: The primary endpoint of this study is to determine the influence of Hb variability with mortality and morbidity of patients. Secondary endpoints are to determine the correlation of methods used to determine Hb variability (Hb standard deviation (SD), Hb residual SD, Hb levels out target 10-12,5g/dL) and the influence of demographic, biochemistry, hematological, and pharmacological variables and co morbidities over Hb variability. Methods: This observational and prospective study carried out in University Hospital Germans Trias i Pujol (Badalona, Spain) included 229 chronic kidney disease (CKD) patients treated with EA in pre-dialysis. Exclusion criteria were: patients with any change in EA treatment during previous 6 months, CKD stages I and II, renal transplantation, thalassemia, glucose-6-phosphate dehydrogenase deficiency, and patients with less than 3 Hb determinations. Observation period was 18 months. Results: Out 229, 109 (47,6%) were females, with 70.44 years of median age (range 25-94),median BMI of 28.29 kg/m2(range 16.40-46.86), with 34% , 52% and 14% of CKD stages III, IV and V respectively.23 patients were treated with EPO beta, 149 with darbepoetina alpha and 57 with CERA. Only 24% and 29.3% of patients achieved 4 or 3 Hb determinations on target (10-12,5g/dL). Methods for Hb variability determination were correlated (p=0.000). No Hb variability correlation with mortality were found (p=0.569. An increase of hospitalization rate was obtained (p=0.05) and with a longer inpatient stay (5 days). Also renal function decline was higher in patients with high Hb variability (p=0.05). Plasma levels of calcium SD, urate SD, fibrinogen, albumin and ferritin were correlated with Hb variability (p≤0.05). More prolonged EA administration were related with less Hb variability ( p=0.001) and concomitant administration of ACEI, antiretrovirals and cytostatics increase Hb variability (p≤0.05). Only cerebral vascular disease, bleeding and transfusions were affected Hb variability (p≤0.05). Conclusions: In pre-dyalisis EA treated patients, high Hb variability increase morbidity (hospitalization and renal function decline). Therapeutic regime of EA and concomitant medication as ACEI, antiretrovirals and cytostatics may affect Hb variability.
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Vázquez, Fernández Iago. "Aprendizaje histórico en gestión de bienes comunales: los pastos en Cantabria (España)." Doctoral thesis, Universidad de Cantabria, 2016. http://hdl.handle.net/10803/380745.
Full textAbstract:
Los montes de Cantabria albergan bienes comunales de indudable valor económico para las poblaciones rurales, uno lo suministra el bosque, es la leña que se emplea para proveer de fuego y calor a los hogares; otro son los pastos, recursos forrajeros para la alimentación del ganado doméstico. De ambos vienen disponiendo consuetudinariamente los vecinos vinculados a ayuntamientos o juntas vecinales titulares de los montes, lo que popularmente se conoce como el derecho a pastos y leñas. Esta investigación trata sobre los primeros, los denominados pastos comunales, ante la constatación de una progresiva degradación del recurso con graves repercusiones económicas, pero también ambientales, debido a su consideración de hábitats de interés para la conservación a nivel europeo y su localización preferente en espacios naturales protegidos. Tras constatar la dificultad que implica la transferencia de propuestas de mejora, aun sometiéndolas a procesos participativos, se avanza un enfoque metodológico innovador que permita incorporar a la planificación la experiencia histórica de gestión de las poblaciones locales. Con ello se contribuye a formular criterios de gestión coherentes no solo con la naturaleza semi-natural de los pastos, creada y reproducida secularmente por la acción del hombre y el ganado, sino también con los usos y costumbres de la población arraigada en el territorio, hacia quienes es fácil transferir prácticas que perciben como propias.The mountains of Cantabria include Commons of undoubted economic value for the rural population, one of which is provided by the forest, being the firewood that is used to heat the homes; another is the pastures to feed the domestic livestock. Both have been used by customary right by the residents in the municipalities or parishes which are the titleholders of the land. This research concerns the former, those known as common pastures, due to progressive degradation of the resource with serious economic repercussions, and also environmental consequences, as a result of their status as habitats of interest for conservation at a European level, and their location mainly in protected areas. After recognizing the difficulty of the transmission of proposals for improvement, even when they are submitted to participatory processes, an innovative methodological approach has been started, which allows the inclusion in the planning of the historical experience of management of the local population. In this way a contribution is made both to the planning, coherent with the semi-natural nature of the pastures, created and maintained for centuries by the action of man and livestock, and also in accordance with the traditional uses of the local population, to whom it is easy to transmit practices which they perceive as their own.
Books on the topic "3807th"
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Dougherty, Bernard J. "The history of 3807 Quarter Master Truck Company". [Place of publication not identified]: [publisher not identified], 2005.
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Williams, Theodore Joseph. We went to war. West Lafayette, IN: T.J. Williams, 1999.
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Gomm, Kevin. Red sun on the Kangaroo Paw: Japanese air raids and attacks on Western Australia during World War II. 3rd ed. Perth, W.A: Helvetica Pub., 2011.
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Manolopoulos, Yannis, Skevos Evripidou, and Antonis C. Kakas, eds. Advances in Informatics. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0.
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Scott, Jill, ed. Artists-in-Labs Processes of Inquiry. Vienna: Springer Vienna, 2006. http://dx.doi.org/10.1007/3-211-38072-8.
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Armenio, Vincenzo, and Sutanu Sarkar, eds. Environmental Stratified Flows. Vienna: Springer Vienna, 2005. http://dx.doi.org/10.1007/3-211-38078-7.
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Breitschwerdt, Lisa. Professionalitätsentwicklung in der Erwachsenenbildung & Weiterbildung als Mehrebenen-Phänomen. Wiesbaden: Springer Fachmedien Wiesbaden, 2022. http://dx.doi.org/10.1007/978-3-658-38076-2.
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Wehrspohn, Uwe, and Dietmar Ernst. Verteilungen als Grundlage des quantitativen Risikomanagements. Wiesbaden: Springer Fachmedien Wiesbaden, 2022. http://dx.doi.org/10.1007/978-3-658-38078-6.
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Wendt, Wolf Rainer. Doing care and doing economy. Wiesbaden: Springer Fachmedien Wiesbaden, 2022. http://dx.doi.org/10.1007/978-3-658-38071-7.
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Giesen, Kristian. Quick Guide Krisenfrüherkennung im Unternehmen. Wiesbaden: Springer Fachmedien Wiesbaden, 2022. http://dx.doi.org/10.1007/978-3-658-38074-8.
Full textBook chapters on the topic "3807th"
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Kumar, M. "3807 Chemical Shifts and Coupling Constants for C16H19N2O3PS." In Chemical Shifts and Coupling Constants for Phosphorus-31, 3816. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-32069-9_3809.
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Corral, Antonio, Joaquin Cañadas, and Michael Vassilakopoulos. "Processing Distance-Based Queries in Multidimensional Data Spaces Using R-trees." In Advances in Informatics, 1–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_1.
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Potamias, George. "Adaptive Classification of Web Documents to Users Interests." In Advances in Informatics, 147–58. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_10.
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Theodoridis, Yannis. "Seismo-Surfer: A Prototype for Collecting, Querying, and Mining Seismic Data." In Advances in Informatics, 159–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_11.
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Tsadiras, Athanasios K., Ilias Kouskouvelis, and Konstantinos G. Margaritis. "Using Fuzzy Cognitive Maps as a Decision Support System for Political Decisions." In Advances in Informatics, 172–82. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_12.
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Avgeriou, Paris, Simos Retalis, and Manolis Skordalakis. "An Architecture for Open Learning Management Systems." In Advances in Informatics, 183–200. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_13.
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Kokkoras, Fotios, Dimitrios Sampson, and Ioannis Vlahavas. "A Knowledge Based Approach on Educational Metadata Use." In Advances in Informatics, 201–16. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_14.
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Avouris, Nikolaos, Nikolaos Tselios, Christos Fidas, and Eleftherios Papachristos. "Website Evaluation: A Usability-Based Perspective." In Advances in Informatics, 217–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_15.
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Vrasidas, Charalambos. "Concepts to Consider when Studying Computer-Mediated Communication and Online Learning." In Advances in Informatics, 232–47. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_16.
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Zaphiris, Panayiotis, and Giorgos Zacharia. "Website Content Accessibility of the Cyprus Domain." In Advances in Informatics, 248–61. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-38076-0_17.
Full textConference papers on the topic "3807th"
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Arriagada, Jaime, Mattia Costantini, Pernilla Olausson, Mohsen Assadi, and Tord Torisson. "Artificial Neural Network Model for a Biomass-Fueled Boiler." In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38070.
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In order to operate plants fueled with biomass in an optimum manner, it is important to create thermodynamic models of the same. However, these kind of plants are hard to model by “traditional” methods such as heat and mass balance programs. Some difficulties are the large inertia of some sub-systems, as well as the fact that many important parameters are not constant nor unequivocally determined. For this reason, Artificial Neural Networks (ANNs), a technique within the field of Artificial Intelligence (AI), have been chosen as the main candidates to build an adequate model of these kind of plants. Data from an existing plant is used to train, validate and test the ANNs. More specifically, an ANN-based model of the biomass-fired boiler of the plant is implemented which is able to catch the non-linear behavior of the system at different operational conditions with a satisfying accuracy. A conclusion of this work is that ANNs can be considered as a useful tool to model the biomass-fueled boiler. Several sensitivity analyses and pruning of unnecessary inputs were carried out. For instance, some input parameters revealed themselves to not have significant influence on the accuracy of the ANN-model, while in physical modeling they are to be considered as essentials. One possible outcome of ANN modeling is to gain insight about which sensors could be excluded from the existing sensor configuration without lowering the reliability of the plant. A good plant model will supply the personnel in the control room with information necessary to make reliable predictions and arrive at correct decisions. This can lead to a considerable reduction of operational and maintenance costs and improved performance of the plant.
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Syverud, Elisabet, Lars E. Bakken, Kyrre Langnes, and Frode Bjo̸rna˚s. "Gas Turbine Operation Offshore: On-Line Compressor Wash at Peak Load." In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38071.
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On-line compressor wash is discussed for a RB211 compressor driver running at peak load at the Statoil Heidrun offshore platform. The oil field’s economy is directly linked to oil production; however, the production rate is limited by driver and gas compressor capacity. From this perspective, the power output and gas turbine uptime become decisive economic factors. The economic potentials related to successful on-line washing are given. This work is based on a series of trials with on-line compressor washing over a two-year period. Results include effect of different on-line washing procedures and washing fluids. The field test campaign has shown no significant improvements with on-line compressor washing at peak load. Understanding the gas turbine performance deterioration is of vital importance. Trending of its deviation from the engine baseline (datum maps) facilitates load-independent monitoring of the gas turbine’s condition. Peak load turbine response to compressor deterioration is analyzed. Instrument resolution and repeatability are key factors that sometimes are more important than absolute accuracy in condition trending. As a result of these analyses, a set of monitoring parameters is suggested for effective diagnostics of compressor degradation in peak load operation. Avenues for further research and development are suggested as our understanding of the deterioration mechanisms at peak load remains incomplete.
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Johnson, Mark W. "A Receptivity Based Transition Model." In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38073.
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A numerical procedure for predicting the receptivity of laminar boundary layers to freestream turbulence, consisting of vortex arrays with arbitrary orientation, has been developed previously. In the current paper this method is refined to improve accuracy using an unstructured computational grid. Results show that boundary layers only have high receptivity to a narrow band of normal and spanwise frequencies. The computed near wall gains have similar values to those obtained by experiment for zero pressure gradient boundary layers. Near wall gains are also obtained for a wide range of favourable and adverse pressure gradients for both attached and separated boundary layers. The gain values are used to predict start of transition values which are in reasonable agreement with Reθ values which are in reasonable agreement with the Abu-Ghannam and Shaw correlations. The current results extend transition inception prediction into the separated flow regime.
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Nair, Suraj, and Tim Lieuwen. "Acoustic Detection of Imminent Blowout in Pilot and Swirl Stabilized Combustors." In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38074.
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This paper describes an experimental effort to characterize the acoustic emissions of lean, premixed combustors operating near blowout conditions. Its objective is to use measurements of the flame’s acoustic signature to determine the proximity of the combustor to incipient blowout. The feasibility of the method was performed on two combustors with fundamentally different flame holding methods: externally anchored pilot and swirl-stabilized. Acoustic measurements indicate that the low frequency spectrum exhibits a strong dependence upon the degree of flame stabilization. High speed intensified camera images of the flame were also taken to get a better understanding of the unsteady flame dynamics. In the piloted burner, it became visibly obvious that the flame was approaching blowoff by increased flickering, unsteadiness, and non-symmetric flame attachment. The results from the swirl burner, however, show that the blow-off transient was characterized by short duration, localized extinction and re-ignition events. These events increase in frequency and duration as blowout is approached. Several data analysis approaches using spectral, statistical and wavelet techniques with varying degrees of sensitivity are shown to be capable of detecting precursors to blowout for both burners.
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Orsagh, Rolf F., Jeremy Sheldon, and Christopher J. Klenke. "Prognostics/Diagnostics for Gas Turbine Engine Bearings." In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38075.
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Development of robust in-flight prognostics or diagnostics for oil wetted gas turbine engine components will play a critical role in improving aircraft engine reliability and maintainability. Real-time algorithms for predicting and detecting bearing and gear failures are currently being developed in parallel with emerging flight-capable sensor technologies including in-line oil debris/condition monitors, and vibration analysis MEMS. These advanced prognostic/diagnostic algorithms utilize intelligent data fusion architectures to optimally combine sensor data, with probabilistic component models to achieve the best decisions on the overall health of oil-wetted components. By utilizing a combination of health monitoring data and model-based techniques, a comprehensive component prognostic capability can be achieved throughout a components life, using model-based estimates when no diagnostic indicators are present and monitored features such as oil debris and vibration at later stages when failure indications are detectable. Implementation of these oil-wetted component prognostic modules will be illustrated in this paper using bearing and gearbox test stand run-to-failure data.
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Jahanian, Omid, and Seyed Ali Jazayeri. "The Effects of Using Formaldehyde as an Additive on the Performance of an HCCI Engine Fueled With Natural Gas." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-38074.
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In this paper, the performance of a natural gas HCCI engine is studied through a thermodynamic model including detailed chemical kinetics. Then the influence of using formaldehyde as an additive on the engine characteristics has been investigated. Results show that it is possible to change engine working limits using this additive. Furthermore, there is an optimum additive content for each operating condition which leads to higher output work and power. It is also shown that the air/fuel mixture will ignite earlier using this additive so it is conceivable to reduce inlet mixture temperature resulting in better performance due to higher volumetric efficiency.
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Yonebayashi, H., K. Ono, H. Enomoto, T. Chida, C.-X. Hong, and K. Fujiwara. "Microbial Enhanced Oil Recovery Field Pilot in a Waterflooded Reservoir." In SPE Asia Pacific Oil and Gas Conference and Exhibition. Society of Petroleum Engineers, 1997. http://dx.doi.org/10.2118/38070-ms.
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Hatch, C. B., and A. O. Dixon. "Trade/Investment in LNG - Asia/Pacific Region." In SPE Asia Pacific Oil and Gas Conference and Exhibition. Society of Petroleum Engineers, 1997. http://dx.doi.org/10.2118/38071-ms.
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Fujita, Kazuo. "Overview And Outlook Of Natural Gas Supply And Demand For Japan." In SPE Asia Pacific Oil and Gas Conference and Exhibition. Society of Petroleum Engineers, 1997. http://dx.doi.org/10.2118/38073-ms.
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Seong, Chen Kah, and Mohamad bin Abdullah. "Peninsular Gas Utilisation Project: Planning And Challenges to Meet Customers Demand From the Perspective of a National Oil Company." In SPE Asia Pacific Oil and Gas Conference and Exhibition. Society of Petroleum Engineers, 1997. http://dx.doi.org/10.2118/38074-ms.
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