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Journal articles on the topic "363.738 498":
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Ditschun, Scott, Nader Soltani, Darren E. Robinson, François J. Tardif, Allan C. Kaastra, and Peter H. Sikkema. "Control of glyphosate-resistant Canada fleabane [Conyza canadensis (L.) Cronq.] with isoxaflutole and metribuzin tank mix." Canadian Journal of Plant Science 96, no. 1 (February 1, 2016): 72–80. http://dx.doi.org/10.1139/cjps-2015-0121.
Abstract:
The future release of ‘Balance GT’ soybean, which is resistant to isoxaflutole and glyphosate, opens up the possibility for control of glyphosate-resistant (GR) Canada fleabane using HPPD-inhibiting herbicides (Group 27) in soybean. Field trials were conducted over two years to evaluate the dose response of an isoxaflutole plus metribuzin tank mix, as well as each chemical applied alone, to assess their response using Flint's adaptation of Colby's equation. Factorial experiments were performed in growth room and greenhouse environments to assess isoxaflutole versus glyphosate, isoxaflutole versus metribuzin, and isoxaflutole plus metribuzin versus glyphosate. Tank mixes of isoxaflutole plus metribuzin in a 1:4 ratio provided 80% control of GR Canada fleabane at a dose range between 420 (84 + 336) and 611 (122 + 489) g a.i. ha−1 at 8 WAA (weeks after application). Tank mixes achieved an 80% reduction in biomass at a dose range between 498 and 738 g a.i. ha−1, while 80% reduction in density was obtained with doses from 96 to 423 g a.i. ha−1, 8 WAA. With glyphosate as a constant tank partner, field treatments of isoxaflutole plus metribuzin were mostly synergistic with some analyses showing an additive response. When tested in the growth room, isoxaflutole plus glyphosate tank mixes indicate additivity in the majority of treatments on glyphosate-susceptible (GS) fleabane.
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Schroter, Sara, Amy Price, Mario Malički, Tessa Richards, and Mike Clarke. "Frequency and format of clinical trial results dissemination to patients: a survey of authors of trials indexed in PubMed." BMJ Open 9, no. 10 (October 2019): e032701. http://dx.doi.org/10.1136/bmjopen-2019-032701.
Abstract:
ObjectiveDissemination of research findings is central to research integrity and promoting discussion of new knowledge and its potential for translation into practice and policy. We investigated the frequency and format of dissemination to trial participants and patient groups.DesignSurvey of authors of clinical trials indexed in PubMed in 2014–2015.ResultsQuestionnaire emailed to 19 321 authors; 3127 responses received (16%). Of these 3127 trials, 2690 had human participants and 1818 enrolled individual patients. Among the 1818, 498 authors (27%) reported having disseminated results to participants, 238 (13%) planned to do so, 600 (33%) did not plan to, 176 (10%) were unsure and 306 (17%) indicated ‘other’ or did not answer. Of the 498 authors who had disseminated, 198 (40%) shared academic reports, 252 (51%) shared lay reports, 111 (22%) shared both and 164 (33%) provided individualised study results. Of the 1818 trials, 577 authors (32%) shared/planned to share results with patients outside their trial by direct contact with charities/patient groups, 401 (22%) via patient communities, 845 (46%) via presentations at conferences with patient representation, 494 (27%) via mainstream media and 708 (39%) by online lay summaries. Relatively few of the 1818 authors reported dissemination was suggested by institutional bodies: 314 (17%) of funders reportedly suggested dissemination to trial participants, 252 (14%) to patient groups; 333 (18%) of ethical review boards reportedly suggested dissemination to trial participants, 148 (8%) to patient groups. Authors described many barriers to dissemination.ConclusionFewer than half the respondents had disseminated to participants (or planned to) and only half of those who had disseminated shared lay reports. Motivation to disseminate results to participants appears to arise within research teams rather than being incentivised by institutional bodies. Multiple factors need to be considered and various steps taken to facilitate wide dissemination of research to participants.
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Zhang, Chuhang. "Fabricating Dispersed Fine Silver Nanoparticles on Liquid Substrate for Improved Photocatalytic Water Splitting Efficiency." Catalysts 13, no. 6 (May 28, 2023): 946. http://dx.doi.org/10.3390/catal13060946.
Abstract:
Dispersed silver nanoparticles (NPs) are synthesized on a silicone oil substrate under varied substrate temperature T by thermal vaporization method. Scanning electron microscopic investigation demonstrates that the mean size of the NPs are around 7.8 nm with a standard deviation of 1.0 nm. The NPs are transferred to a strontium titanate (STO) crystal as co-catalyst for water splitting efficiency test. The photoelectrochmical (PEC) measurement reveals the photocatalytic activity of NP co-catalyst sensitively relies on T during deposition process: the relative current density jr increases from 4.8 μA/cm2 to 25.4 μA/cm2 as T goes up from 253 K to 333 K. However, a slight decrease of jr from 25.4 μA/cm2 to 22.8 μA/cm2 is found as T further increases to 353 K. The dependent behavior of jr on T is explained in term of a competition mechanism between microstructure evolution and growth model of the NPs under different T: for T ranging from 253 K to 333 K, the effect of a higher crystalline structure for NPs fabricated under higher T improves the electron transfer rate from STO to NPs is dominant. As T increases to 353 K, the overlapping of NPs become a factor for photocatalytic activity of NP/STO system: the diffusion distance of electrons becomes larger and the apparent contact area between NPs and STO is reduced which in turn reduce the photocatalytic activity of NP/STO. The experimental method to synthesize NPs in this report may open up a way to further apply fine NPs in enhancing photocatalytic water splitting efficiency.
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Demetrio, D., A. Magalhaes, M. Oliveira, R. Santos, and R. Chebel. "11 Invivo-derived embryo pregnancy rates at Maddox Dairy from 2008 to 2018." Reproduction, Fertility and Development 32, no. 2 (2020): 130. http://dx.doi.org/10.1071/rdv32n2ab11.
Abstract:
Maddox Dairy, located in Riverdale, CA, USA, is a Holstein herd that milks 3500 cows with a 305-day mature-equivalent milk production of 12 800 kg, and they have been producing high genetic animals by embryo transfer (ET) since the early 1980s. Invivo-derived embryos from Holstein donors were transferred fresh (grade 1 or 2) or frozen (grade 1), at morula (4), early blastocyst (5), or blastocyst (6) stage, to virgin heifers (VH, natural oestrus, 13-15 months old) or lactating cows (LC, Presynch-Ovsynch, 86 days in milk, first or second lactation) 6 to 9 days after oestrus. Pregnancy diagnosis was done by transrectal ultrasonography at 32-46 days in VH and by the IDEXX PAG test at 30 days in LC. June, July, August, September, and October were called critical months (first service AI conception rate drops below 44%) and compared with the other months. The data from 32 503 ETs between January 2008 and December 2018 are summarised on Table 1. Pregnancy rates (PR) are lower for LC recipients than for VH. Embryo transfers performed 7 or 8 days after oestrus had higher PR in both types of recipients and embryos, but Day 6 and 9 oestrus are also used with fair results. The season does not seem to affect PR. There is not enough difference in the combination of stage and days from oestrus for invivo-derived embryos. These numbers do not belong to a planned experiment. Several management changes during the years were made, which make it very difficult to apply statistical methods to analyse the data correctly. They are used as a tool to make decisions in an attempt to improve future results. Table 1.Pregnancy rate (PR) of virgin heifers (top) and lactating cows (bottom)-fresh (SH) and frozen (OZ) invivo-derived embryo transfer1 Heat-months SH-ST4 SH-ST5 SH-ST6 SH-All OZ-ST4 OZ-ST5 OZ-ST6 OZ-All PR% n PR% n PR% n PR% n PR% n PR% n PR% n PR% n Heifers 6 d-CM 62 934 66 243 68 69 63 1246 56 473 58 219 62 42 57 734 6 d-OM 62 1623 67 489 69 211 64 2323 56 600 55 296 48 137 55 1033 6 d-T 62 2557 67 732 69 280 63 3569 56 1073 57 515 51 179 56 1767 7 d-CM 64 1506 68 495 67 221 65 2222 60 822 62 340 63 156 61 1318 7 d-OM 66 2723 68 1021 69 510 67 4254 57 1120 59 581 57 231 58 1932 7 d-T 66 4229 68 1516 69 731 67 6476 58 1942 60 921 60 387 59 3250 8 d-CM 65 1348 64 518 67 322 65 2188 59 595 64 258 63 108 61 961 8 d-OM 66 2166 68 886 70 510 67 3562 61 770 60 364 51 130 60 1264 8 d-T 66 3514 67 1404 69 832 66 5750 60 1365 62 622 56 238 60 2225 9 d-CM 60 109 56 43 70 20 60 172 60 5 33 6 50 4 47 15 9 d-OM 58 129 63 57 60 40 60 226 63 16 50 18 75 4 58 38 9 d-T 59 238 60 100 63 60 60 398 62 21 46 24 63 8 55 53 All-CM 64 3897 66 1299 67 632 65 5828 58 1895 61 823 63 310 60 3028 All-OM 65 6641 67 2453 69 1271 66 10 365 58 2506 58 1259 53 502 58 4267 All-T 65 10 538 67 3752 69 1903 66 16 193 58 4401 60 2082 57 812 59 7295 Lactating cows 6 d-CM 54 265 48 86 50 12 53 363 38 141 31 77 50 10 36 228 6 d-OM 49 463 52 203 45 56 50 723 46 101 48 54 59 27 48 182 6 d-T 51 728 51 289 46 68 51 1086 41 242 38 131 57 37 42 410 7 d-CM 54 755 59 274 56 103 55 1137 43 928 48 450 43 192 45 1570 7 d-OM 55 914 66 367 54 109 58 1393 46 1052 45 564 47 353 46 1969 7 d-T 55 1669 63 641 55 212 57 2530 45 1980 46 1014 46 545 45 3539 8 d-CM 63 252 68 82 76 33 65 368 48 219 56 80 42 33 50 332 8 d-OM 61 257 64 161 53 47 61 466 50 191 53 77 56 16 51 284 8 d-T 62 509 65 243 63 80 63 834 49 410 55 157 47 49 50 616 All-CM 56 1272 58 442 60 148 57 1868 44 1288 47 607 43 235 45 2130 All-OM 55 1634 62 731 51 212 56 2582 47 1344 46 695 48 396 47 2435 All-T 55 2906 60 1173 55 360 57 4450 45 2632 47 1302 46 631 46 4565 1ST=stage; CM=critical months (June, July, August, September, and October); OM=other months.
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Pinderhughes, Dianne. "DISGUST, VISIBLE VENERATION, AND ROSA PARKS: African American Visions of a Democratic America." Du Bois Review: Social Science Research on Race 2, no. 2 (September 2005): 303–17. http://dx.doi.org/10.1017/s1742058x05050228.
Abstract:
Melissa Victoria Harris-Lacewell, Barbershops, Bibles, and BET: Everyday Talk and Black Political Thought. Princeton, NJ: Princeton University Press, 2004, 336 pages, ISBN: 0-691-11405-6, Cloth, $37.95.Barbara Ransby, Ella Baker and the Black Freedom Movement: A Radical Democratic Vision. Chapel Hill, NC: University of North Carolina Press, 2003, 496 pages, ISBN: 0-8078-2778-9, Cloth, $34.95, ISBN: 0-8078-5616-9, Paper, $19.95.Ange-Marie Hancock, The Politics of Disgust: The Public Identity of the Welfare Queen. New York: New York University Press, 2004, 210 pages, ISBN: 0-814-736-580, Cloth, $60.00, ISBN: 0-814-736-70X, Paper, $20.00.
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Maharani, Puspita Laksmi, Prijanto Pamoengkas, and Irdika Mansur. "PEMANFAATAN POME SEBAGAI PUPUK ORGANIK PADA LAHAN PASCATAMBANG BATUBARA The Application of POME (Palm Oil Mill Effluent) as Organic Fertilizer for Ex-Coal Mine Soil." Journal of Tropical Silviculture 8, no. 3 (March 19, 2018): 177–82. http://dx.doi.org/10.29244/j-siltrop.8.3.177-182.
Abstract:
Processing of palm oil generates enormous quantities of wastewater commonly called palm oil mill effluent (POME). The aim of the research was to evaluate the effect of POME as organic fertilizer on Melaleuca cajuputi seedling. The research was conducted at PT. Bukit Asam from November 2016 until March 2017. POME used was from PT. Bumi Sawindo Permai at Tanjung Enim, South Sumatera. POME from Fat pit, cooling pond, anaerob pond and maturity pond were applied to seedlings at nursery with different concentrations of POME Fat pit (625, 417, and 208 mL), Cooling pond (695, 463, dan 232 mL), Anaerob pond (738, 492, dan 246 mL), and Maturity pond (968, 645, dan 323 mL). The result showed that POME from Anaerob pond 246 mL increased the growth of M. cajuputi with plant high 47.35 cm and stem diameter 5.57 mm and total dry weight of CM (Calopogonium mucunoides) was 26.83 g.Key words: ex-coal mine soil, Melaleuca cajuputi, POME
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Prynne, CJ, AA Paul, GM Price, KC Day, WS Hilder, and MEJ Wadsworth. "Food and nutrient intake of a national sample of 4-year-old children in 1950: comparison with the 1990s." Public Health Nutrition 2, no. 4 (April 1999): 537–47. http://dx.doi.org/10.1017/s1368980099000725.
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AbstractObjective:To evaluate the food and nutrient intake of members of a birth cohort study when young children in 1950 and investigate differences from present-day children's diets.Design:One-day recall diet records from the MRC National Survey of Health and Development (NSHD) (1946 Birth Cohort) at age 4 years were analysed for energy and selected nutrients and compared to the published results for 4-year-olds in the 1992/93 National Diet and Nutrition Survey (NDNS).Setting:England, Scotland and Wales in 1950 and 1992/93.Subjects:4599 children in 1950 and 493 children in 1992/93.Results:Mean (SD) daily intakes in 1950 were energy 1445 (343) kcal, or 6.1 (1.4) MJ, protein 46 (11)g, fat 64 (20)g, starch 117 (33)g, sugar 62 (24)g, unavailable carbohydrate 13 (4)g, calcium 736 (230)mg, iron 7.7 (2.1)mg, retinol 738 (1273) μg, carotene 1049 (1130) μg and vitamin C 40 (26) mg. Compared to 1992/93, the 1950 diet contained substantially more bread and vegetables and less sugar and soft drinks, giving it a higher starch and fibre content and making it more in line with current recommendations on healthy eating. However, fat provided 40% of energy in 1950, compared to 35% in 1992/93. In 1950, red meat was an important source of iron, but by 1992 most iron came from fortified breakfast cereals. Vitamin C came mainly from vegetables in 1950, but from soft drinks in 1992.Conclusions:The relative austerity of post-war food supplies resulted in food and nutrient intakes in 1950 which in many respects may well have been beneficial to the health of young children, despite fat intake being higher than present-day recommendations.
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Bateman, Francis, Oluwatobi Arisa, Natalia Corvalan Cabanas, Yi Zeng, Cody Peer, Keith Schmidt, and William Douglas Figg. "Abstract 7184: Simulating extended dosing intervals for atezolizumab: A comparative analysis between NONMEM and Pumas." Cancer Research 84, no. 6_Supplement (March 22, 2024): 7184. http://dx.doi.org/10.1158/1538-7445.am2024-7184.
Abstract:
Abstract The initially approved dosage regimens of 840 mg every 2 weeks, 1200 mg every 3 weeks, and 1680 mg every 4 weeks are considered excessive concerning the specified minimum effective concentration of 6 ug/mL and the significant exposure-response relationship with Adverse Events of Special Interest (AESI). Our previous research, demonstrated through simulation, indicated that an extended-interval dosing regimen (840 mg every 6 weeks) after two standard loading doses maintained efficacy with a nonsignificant exposure-response relationship with AESI.In alignment with the FDA's initiative "Project Optimus," which aims to optimize drug dosing for improved therapeutic outcomes, we explore alternative dosage regimens for atezolizumab. Through a comparison of the traditional 30-year-old industry standard NONMEM software and the recently developed PumasAI software, we simulate these regimens, utilizing our previously published article as a benchmark. Given the rapid evolution of artificial intelligence (AI) and machine learning, it is crucial for pharmacokinetic modeling to adapt and leverage these advancements. We anticipate that this paper will contribute to the integration of AI and machine learning software in pharmacokinetic analysis, aligning with the goals of "Project Optimus" to ensure that drug concentrations are optimized for efficacy and safety. Table 1: Comparative Summary of Simulated Pharmacokinetic Parameters: Pumas vs. NONMEM Pumas NONMEM Regimen Cycle Week Cmax (ug/mL) Cmax (ug/mL) Cmax (ug/mL) Cmax (ug/mL) Cmin (ug/mL) Weekly AUC (ug*day/mL) 1200 mg q3w 1st 3 384(278-533) 64.1(31.4-112) 919(640-1290) 394 (278-559) 75.6 (44.5-121) 1003 (755-1342) 7th 21 541(371-795) 146(53.8-349) 1750(977-3210) 583 (414-847) 180 (75.9-396) 2014 (1169-3535) 840 mg q2w x2, 840 mg q6w 1st 2 270(195-379) 61.6(35.5-100) 775(570-1085) 275 (184-397) 71.2 (46.4-108) 834 (620-1131) 7th 38 314(221-448) 33.6(8.8-127) 650(357-1375) 336 (235-487) 46.9 (13.5-150) 774 (441-1562) 1200 mg q3w x2, 840 mg q6w 1st 3 384(278-533) 64.1(31.4-112) 919(640-1290) 394 (278-559) 75.6 (44.5-121) 1003(755-1342) 7th 39 316(224-459) 36.0(8.4-129) 670(340-1406) 327 (217-492) 46.6 (13.4-157) 763 (411-1594) 1680 mg q4w x2, 840 mg q6w 1st 4 545(380-779) 63.1(26.9-122) 1096(735-1555) 552 (375-793) 78.1 (40.7-135) 1203(869-1651) 7th 40 318(222-469) 33.9(7.7-126) 657(343-1385) 332 (227-491) 46.5 (13.6-140) 771 (436-1464) Citation Format: Francis Bateman, Oluwatobi Arisa, Natalia Corvalan Cabanas, Yi Zeng, Cody Peer, Keith Schmidt, William Douglas Figg. Simulating extended dosing intervals for atezolizumab: A comparative analysis between NONMEM and Pumas [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 7184.
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Zanaboni, Paolo, Per Egil Kummervold, Tove Sørensen, and Monika Alise Johansen. "Patient Use and Experience With Online Access to Electronic Health Records in Norway: Results From an Online Survey." Journal of Medical Internet Research 22, no. 2 (February 7, 2020): e16144. http://dx.doi.org/10.2196/16144.
Abstract:
Background The electronic health record (EHR) has been fully established in all Norwegian hospitals. Patient-accessible electronic health records (PAEHRs) are available to citizens aged 16 years and older through the national health portal Helsenorge. Objective This study aimed at understanding how patients use PAEHRs. Three research questions were addressed in order to explore (1) characteristics of users, (2) patients’ use of the service, and (3) patient experience with the service. Methods We conducted an online survey of users who had accessed their EHR online at least once through the national health portal. Patients from two of the four health regions in Norway were invited to participate. Quantitative data were supplemented by qualitative information. Results A total of 1037 respondents participated in the survey, most of whom used the PAEHR regularly (305/1037, 29.4%) or when necessary (303/1037, 29.2%). Service utilization was associated with self-reported health, age, gender, education, and health care professional background. Patients found the service useful to look up health information (687/778, 88.3%), keep track of their treatment (684/778, 87.9%), prepare for a hospital appointment (498/778, 64.0%), and share documents with their general practitioner (292/778, 37.5%) or family (194/778, 24.9%). Most users found it easy to access their EHR online (965/1037, 93.1%) and did not encounter technical challenges. The vast majority of respondents (643/755, 85.2%) understood the content, despite over half of them acknowledging some difficulties with medical terms or phrases. The overall satisfaction with the service was very high (700/755, 92.7%). Clinical advantages to the patients included enhanced knowledge of their health condition (565/691, 81.8%), easier control over their health status (685/740, 92.6%), better self-care (571/653, 87.4%), greater empowerment (493/674, 73.1%), easier communication with health care providers (493/618, 79.8%), and increased security (655/730, 89.7%). Patients with complex, long-term or chronic conditions seemed to benefit the most. PAEHRs were described as useful, informative, effective, helpful, easy, practical, and safe. Conclusions PAEHRs in Norway are becoming a mature service and are perceived as useful by patients. Future studies should include experimental designs focused on specific populations or chronic conditions that are more likely to achieve clinically meaningful benefits. Continuous evaluation programs should be conducted to assess implementation and changes of wide-scale routine services over time.
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Senturk, V., M. Abas, M. Dewey, O. Berksun, and R. Stewart. "Antenatal depressive symptoms as a predictor of deterioration in perceived social support across the perinatal period: a four-wave cohort study in Turkey." Psychological Medicine 47, no. 4 (November 22, 2016): 766–75. http://dx.doi.org/10.1017/s0033291716002865.
Abstract:
BackgroundIn a perinatal cohort of women in urban and rural Turkey, we investigated associations between antenatal depressive symptoms and subsequent changes in perceived quality of key family relationships.MethodOf 730 women recruited in their third trimester (94.6% participation), 578 (79.2%) were reassessed at a mean of 4.1 (s.d. = 3.3) months after childbirth, 488 (66.8%) were reassessed at 13.7 (s.d. = 2.9) months, and 448 (61.4%) at 20.8 (s.d. = 2.7) months. At all four examinations, self-reported quality of relationship with the husband, mother and mother-in-law was ascertained using the Close Persons Questionnaire with respect to emotional support, practical support and negative aspects of the relationship. Antenatal depressive symptoms were defined using the Edinburgh Postnatal Depression Scale. A range of covariates in mixed models was considered including age, education, number of children, family structure, physical health, past emotional problems and stressful life events.ResultsKey findings were as follows: (i) reported emotional and practical support from all three relationships declined over time in the cohort overall; (ii) reported emotional support from the husband, and emotional and practical support from the mother-in-law, declined more strongly in women with antenatal depressive symptoms; (iii) associations between depressive symptoms and worsening spouse relationship were more pronounced in traditional compared with nuclear families.ConclusionsAntenatal depressive symptoms predicted marked decline in the quality of key relationships over the postnatal period. This may account for some of the contemporaneous associations between depression and worse social support, and may compound the risk of perinatal depression in subsequent pregnancies.
Books on the topic "363.738 498":
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Innovación Docente y Calidad Institucional : Jornadas de Innovación Docente e Investigación Educativa UZ, Zaragoza, 5 y 6 de septiembre de 2019. Universidad de Zaragoza, 2021. http://dx.doi.org/10.26754/uz.978-84-09-29715-3.
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Índice de Contenidos Aplicación de metodologías activas I 9 Estrategias de gamificación, y aprendizaje entre pares, para la adquisición de competencias 13 Herramientas para la gestión de los recursos digitales en los procesos de enseñanza-aprendizaje 28 Gamificación de la Cristalografía mediante la App XtereO 40 Educación Visual y Plástica comprometida con el entorno próximo 49 Experiencias de coordinación entre el profesorado 67 Diseño de actividades multidisciplinares de Ciencias de la Naturaleza y Matemáticas 71 Evaluación del aprendizaje 99 Impacto del Concurso de Cristalización en la Escuela en Aragón en el profesorado participante. 103 ¿Influye el género en la evaluación entre iguales? 113 Acciones de integración y orientación de estudiantes 133 Competencias digitales para estudiantes de la Universidad de Zaragoza 158 La organización emocional del aula en la gestión de la actividad docente 164 La motivación como herramienta para mejorar la tasa de aprobados en la asignatura de Contabilidad Financiera II. 20 Gamificación a través de diferentes aplicaciones como innovación docente en el grado de Ciencias de la Actividad Física y del Deporte 33 Utilización de vídeos y cuestionarios para la mejora del proceso de enseñanza-aprendizaje de conocimientos requeridos en la asignatura “Criterios de diseño de máquinas” 58 Acercando a los estudiantes de magisterio una experiencia colaborativa realizada en Educación Primaria 78 La formación de los futuros maestros desde un modelo interdisciplinar para las enseñanzas de Lengua Castellana y LIJ. 88 Evaluación de necesidades y seguimiento del aprendizaje en competencias de comunicación académica en inglés a través de un focus group en ADEi 121 Percepción de los estudiantes de los grados de la Facultad de Economía y Empresa sobre el uso y utilidad de las tutorías 137 Integración de los estudiantes de ADE en el mercado laboral a través del programa de prácticas y actividades externas. 148 Promoviendo la reflexión entre docentes acerca delas bases fundamentales sobre las que construirla ciudadanía digital 171 Estudio de opinión de los alumnos del Grado en Medicina sobre las limitaciones éticas de la ciencia 179 Percepción social de la ciencia por los alumnos del Grado en Medicina 185 La dirección de Trabajos Fin de Grado (TFG) en el marco de las nuevas modalidades de educación universitaria a distancia: algunas claves metodológicas para su adecuada ejecución 191 Experiencia piloto para mejorar las competencias de trabajo en equipo y comunicación oral en asignaturas de ingeniería 198 Otras metodologías activas II. 207 Metodologías activas basadas en juegos de razonamiento para fomentar el aprendizaje 211 El dispositivo móvil en el aula, ¿herramienta educativa o distracción? 217 Mejora de la adquisición de competencias a través del modelo de aula inversa 224 El customer journey map en la formación de la empatía y la innovación 232 La gamificación en el aula para la mejora de la participación del alumno en el estudio de la asignatura de Esplacnología. 239 Los cuestionarios Moodle como una herramienta para mejorar la calidad de la docencia y fomentar el aprendizaje en el aula universitaria 246 Un canal de YouTube como mecanismo de adquisición de competencias transversales 251 Arte y reciclaje en los entornos educativos (Trash art) 260 Didáctica con la gamificación y el videojuego mediante una intervención multidisciplinar para estudiantes del Grado de Maestro 270 YouTube como repositorio de vídeos docentes de apoyo a la docencia 278 Aplicación de Metodologías Activas III 287 Combinación de la Técnica Just in Time Teaching y los Serious Games con el enfoque pedagógico Flipped Learning en Educación Superior 291 Aprendizaje de lenguas para la inclusión social 303 Gamificación y role playing en la enseñanza de Derecho Procesal Penal, intervención de la Persona Jurídica y cumplimiento normativo 310 Integrando diferentes aplicaciones TIC en la docencia universitaria: uso de Screencast-o-matic, Canva y Pocket 317 Evaluación del uso de diferentes TIC en la docencia universitaria: grupo MultiFlipTech 323 Experiencias de mejora de la calidad de las titulaciones 335 Coordinación de agentes y mejora de los instrumentos de evaluación de las prácticas escolares: selección de las dimensiones a calificar 339 Enseñanza a distancia en el grado en Gestión y Administración Pública 345 Selección y rendimiento de los estudiantes en la asignatura Organización y Gestión Interna 356
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Certain sodium sulfur chemical compounds from the Federal Republic of Germany, the People's Republic of China, Turkey, and the United Kingdom: Determination of the Commission in investigation no. 701-TA-303 (preliminary) under the Tariff Act of 1930, together with the information obtained in the investigation; determinations of the Commission in investigations nos. 731-TA-465-468 (preliminary) under the Tariff Act of 1930, together with the information obtained in the investigations. Washington, D.C: U.S. International Trade Commission, 1990.
Book chapters on the topic "363.738 498":
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Dorf, Michael C. "Abstract and Concrete Review." In Global Perspectives on Constitutional Law, 3–14. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195328103.003.0001.
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Abstract The U.S. Supreme Court has interpreted the case-or-controversy language of Article III to impose rigorous standing requirements for adjudication in all federal courts, including constitutional cases in the Supreme Court itself. “At a minimum, the standing requirement is not met unless the plain- tiff has ‘such a personal stake in the outcome of the controversy as to assure that concrete adverseness which sharpens the presentation of issues upon which the court so largely depends. . . .’ “ Allen v. Wright, 468 U.S. 737, 770 (1984) (quoting Baker v. Carr, 369 U.S. 186, 204 (1962)). Standing and related doctrines such as ripeness and mootness implement a broader prohibition on the issuance of advisory opinions. In constitutional litigation, these limits on the powers of Article III courts collectively characterize the American version of a practice that sometimes goes by the name of “concrete review.”
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Taber, Douglass F. "C-O Ring Construction: (-)-Sclerophytin A (Morken), (+)-Dictyosphaeric Acid (Taylor), Goniothalesdiol A (Xie/She), (-)-7-Deoxyloganin (Lupton), (-)-Apicularen A (Uenishi), L-783, 277(Banwell) 100." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0052.
Abstract:
In the course of a synthesis of (-)-sclerophytin A 3, James P. Morken of Boston College showed (J. Am. Chem. Soc. 2010, 132, 16380) that Oshima-Utimoto conditions transformed 1 into 2 with high stereo-and regiocontrol. En route to (+)-dictyosphaeric acid 6, Richard J. K. Taylor of the University of York found (Angew. Chem. Int. Ed. 2010, 49, 5574) that the intramolecular Michael cyclization of 4 proceeded smooothly to give 5. Xingang Xie and Xuegong She of Lanzhou University devised (Synlett 2010, 2283) the In-mediated cyclization of 7 with benzaldehyde, to effect an elegant synthesis of goniothalesdiol A 9. The carbene-mediated cyclization of 10 to 11 developed (Org. Lett. 2010, 12, 4836) by David W. Lupton of Monash University set the stage for the synthesis of (-)-7-deoxyloganin 12. Jun’ichi Uenishi of Kyoto Pharmaceutical University showed (Org. Lett. 2010, 12, 4160) that the Pd-mediated cyclization of 13 proceeded with high diastereocontrol. Intramolecular esterification than led to (-)-apicularen A 15. Martin G. Banwell of the Australian National University established (Heterocycles 2010, 82, 313) that LiHMDS was effective for the cyclization of the alkynyl Weinreb amide 16 to 17. Reduction and deprotection completed the synthesis of the resorcylic lactone L-783, 277 18.
3
Taber, Douglass F. "Organocatalysis of Carbocyclic Construction: The MacMillan Synthesis of (+)-Frondosin B." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0071.
Abstract:
One of the more powerful applications of organocatalysis has been the enantioselective transformation of preformed prochiral rings. In the five-membered ring series, Nobuyuki Mase of Shizuoka University effected (Synlett 2010, 2340) enantioselective addition of malonate to cyclopentenone 1, and Eric N. Jacobsen of Harvard University devised (Angew. Chem. Int. Ed. 2010, 49, 9753) a guanidinium catalyst for the Claisen rearrangement of 4 to 5. Jacek Mlynarski of Jagiellonian University accomplished (Tetrahedron Lett. 2010, 51, 4088) the enantioselective hydroxymethylation of 6. This worked equally well for cyclopentanone and cycloheptanone. The dynamic kinetic resolution/reductive amination of 8 described (Angew. Chem. Int. Ed. 2010, 49, 4612) by Benjamin List of the Max-Planck-Institut Mülheim worked best with cyclohexanones such as 8. Organocatalysts can also be effective for the construction of carbocyclic rings. Teck-Peng Loh of Nanyang Technological University found (Chem. Sci. 2010, 1, 739) a commercial phosphine catalyst that efficiently mediated the condensation of 10 with 11. David W. C. MacMillan of Princeton University used (J. Am. Chem. Soc. 2010, 132, 10015) a SOMO catalyst to combine 13 with 14 to make 15. Dawei Ma of the Shanghai Institute of Organic Chemistry employed (Org. Lett. 2010, 12, 3634) the Hayashi catalyst in the double Michael condensation of 16 with 17. Daniel Romo of Texas A&M University showed (Org. Lett. 2010, 12, 3764) that the appropriate organocatalyst could direct 19 to either diastereomer of the β-lactone 20. Professor Romo also reported (Angew. Chem. Int. Ed. 2010, 49, 9479) the desymmetrization of 2-alkyl cyclohexane-1,3-diones using a similar approach. In the six-membered ring series, José Alemán and José Luis García Ruano of the Universidad Autónoma de Madrid carried out (Eur. J. Org. Chem. 2010, 4482) Robinson annulation of 17 with 21. Ying-Chun Chen of Sichuan University, again using the Hayashi catalyst, reported (Angew. Chem. Int. Ed. 2010, 49, 6418) the addition of 17 to 23 to give 24. In another elegant application of visible light–mediated organocatalysis, Professor MacMillan described (Chem. Sci. 2010, 1, 37) the addition of the commercial boronic acid 25 to 17.
4
Taber, Douglass. "Preparation of Heteroaromatic Derivatives." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0067.
Abstract:
Several new routes to furans and to pyrroles have recently been put forward. Inspired by the Achmatowicz ring expansion, Patrick J. Walsh of the University of Pennsylvania developed (J. Am. Chem. Soc. 2008, 130, 4097) the oxidative rearrangement of 3-hydrox-alkyl furans such as 1 to the 3-aldehyde 2. José M. Aurrecoechea of the Universidad del País Vasco established (J. Org. Chem. 2008, 73, 3650) that cumulated alcohols, available by reduction of alkynes such as 3 with SmI2, rearrange under Pd catalysis, and then add to an acceptor alkene such as 4, to give the furan 5. Vladimir Gevorgyan of the University of Illinois at Chicago used (J. Am. Chem. Soc. 2008, 130, 1440) an Au catalyst to rearrange an allene such as 6 to the bromo furan 7. Fabien L. Gagosz of the Ecole Polytechnique, Palaiseau, also found (Organic Lett. 2007, 9, 3181) that an Au catalyst rearranged the eneyne 8 to the pyrrole 9. Azido esters such as 10 are readily prepared from the corresponding aldehyde by phosphonate condensation. Shunsuke Chiba and Koichi Narasaka of Nanyang Technology University demonstrated (Organic Lett. 2008, 10, 313) that thermal condensation of 10 with acetyl acetone 11 gave the pyrrole 12, while Cu catalyzed condensation with acetoacetate 13 gave the complementary pyrrole 14. Huan-Feng Jiang of South China University of Technology observed (Tetrahedron Lett. 2008, 49, 3805) that condensation of an acid chloride 15 with an alkyne 16, presumably to give the alkynyl ketone, followed by the addition of hydrazine delivered the pyrazole 17. Masanobu Uchiyama of RIKEN and Florence Mongin of the Université de Rennes 1 established (J. Org. Chem. 2008, 73, 177) that a pre-formed pyrazole 18 could be metalated and then iodinated, to give 19. Xiaohu Deng of Johnson & Johnson, San Diego reported (Organic Lett. 2008, 10, 1307; J. Org. Chem. 2008, 73, 2412) complementary routes to pyrazoles, combining 20 and 21 under acidic conditions to give 22, and under basic conditions to give 23.
5
Taber, Douglass F. "C-H Functionalization: The White Synthesis of 6-Deoxyerythronolide B." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0018.
Abstract:
Masayuki Inoue of the University of Tokyo designed (Organic Lett. 2009, 11, 3630) a linker that specifically directed C-H hydroxylation, as illustrated by oxidation of 1 to 2. Phil S. Baran of Scripps/La Jolla detailed (Nature 2009, 459, 824; Angew. Chem. Int. Ed. 2009, 48, 9705) some of the factors that direct reactivity in intermolecular C-H hydroxylation. Ning Jiao of Peking University devised (Angew. Chem. Int. Ed. 2009, 48, 7094) a protocol for the direct oxidation of a methylated aromatic 3 to the nitrile 4. Armando J. L. Pombeiro of TU Lisbon developed (Adv. Synth. Cat. 2009, 351, 2936) a procedure for C-H carboxylation, converting 5 into 6. Maurizio Fagnoni of the University of Pavia showed (Chem. Commun. 2009, 7351) that sunlight was sufficient to promote the addition of cyclohexane 7 to methyl acrylate to give 8. Jin-Quan Yu, also of Scripps/La Jolla, established (J. Am. Chem. Soc. 2009, 131, 9886) conditions for the selective Pd-mediated coupling of 9 to iodobenzene to give 10. Alexei V. Novikov of the University of North Dakota demonstrated (Tetrahedron Lett. 2009, 50, 6963; Heterocycles 2009, 78, 2531) that both diazo sulfonates such 11 and the related diazo sulfones cyclized smoothly under Rh catalysis to give the six-membered ring products. In the course of a synthesis of the Psoralea corylifolia –derived bakuchiol, the adduct from the cyclization of 11 was converted into the vinylated product 12. C-H bonds can also be activated electronically by proximal functional groups. Yong-Min Liang of Lanzhou University observed (J. Org. Chem. 2009, 74, 7464) that an N-aryl cyclic amine 13 could be oxidized to the syn diacetoxylated product 14. Note that the α-acetoxy group of 14 is activated for ionization and further bond formation. Yuhong Zhang of Zhejiang University, Hangzhou, found (Organic Lett. 2009, 11, 3730) that the activated intermediate from the oxidation of 15 coupled with a silyl enol ether to deliver the coupled product 16. Bernd Plietker of the Universität Stuttgart devised (Angew. Chem. Int. Ed. 2009, 48, 5752) a Ru catalyst for the coupling of an alkyne 18 to an α,β-unsaturated ester 17 to give the diene 19. Both disubstituted alkynes and more complex α,β-unsaturated esters participated as well. Gregory K. Friestad of the University of Iowa observed (Organic Lett. 2009, 11, 819) that an N-vinyl amide 20 could be homologated to the ester 22.
Conference papers on the topic "363.738 498":
1
Velasquez, Joshua D., Boian T. Alexandrov, and Steven L. McCracken. "Hydrogen Induced Cracking Susceptibility in the Heat Affected Zone of SA-508 Pressure Vessel Steel." In ASME 2022 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/pvp2022-84781.
Abstract:
Abstract ASME Case N-888, Similar and Dissimilar Metal Welding Using Ambient Temperature SMAW and Machine GTAW Temper Bead Technique, requires a 48-hour hold time before nondestructive examination (NDE) can be performed to ensure hydrogen-induced cracking (HIC) did not occur. The aim of this work is to assess and characterize the HIC susceptibility of SA-508 pressure vessel steel. The results from this study will be used to consider potential elimination of the NDE hold time requirement in Case N-888. The Gleeble™ thermo-mechanical simulator was used to recreate CGHAZ for five weld conditions; as-welded, post-weld heat treated (PWHT), and four single-reheat temperatures of 675 °C, 700 °C, 725 °C, and 735 °C to simulate temper bead welding (TBW). Metallurgical characterization revealed a tempered martensitic microstructure for all TBW and the PWHT conditions. The 735 °C TBW sample developed ferrite along the prior austenite grain boundaries. The single reheats to 675 °C, 700 °C and 735 °C reduced the as-welded CGHAZ hardness from 425HV0.5 respectively to 313, 298, and 278HV0.5. A fourth TBW condition was added at 725 °C to eliminate ferrite formation seen at 735 °C. The TBW at 725 °C produced a microstructure of tempered martensite with a hardness of 298HV0.5. The HIC susceptibility is being evaluated using the Delayed Hydrogen Crack Test (DHCT) developed at the Ohio State University. Samples of SA-508 steel with the five CGHAZ microstructural conditions are loaded at 90% of the base metal yield strength and simultaneously electrolytically charged with hydrogen. The HIC susceptibility is ranked by the time to failure (full specimen separation) and sustained mechanical energy.
2
Woods, A. I., and M. A. Lazzari. "ASPIRIN FAILURE TO INHIBIT THE RELEASE OF PLASMINOGEN ACTIVATORS-INHIBITORS BY HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643126.
Abstract:
Platelet-PA-Inhibitors can be released by thrombin, Col laaen( Col) and others.If they are physiologically important,inhibition of their release might facilitate thrombolysis.Intrinsic PA were tested in euclobulins (eug)of PPP and PPP+Washed platelets(WP) ,with and without aspirinf ASA) .treated with UK,SK and Col(20 atfd l2uo/ml) Results(mm2)were:euaPPP:232+78;+3×106WP/ul:217+71;+10%7ul:188+/5 +2×106MP/ul: 157+69:With UK:eugPPP:283+76;+3×l0517P/ul :234+69;+106 WP/ul :172+55;+2×l(PWP/ul :154+48; With SK:euoPPP:303+99;+3×l05WP/ul 252+65;+1067P/ul:203+68;+2×106UP/ul: 174+85;Wi th Col (20ug/ml) :eur PPP:234+97;+3×105WP/ul:160+63;+106WP/ul:141+73;+2×l06WP/ul:129+81; +2×106WP/ul+ASA: 105+31;Wi th Col uc/ml) :euaPPP:230+56;+3×l05NP/ul: 160+52;+106WP/ul:139+44;+2×106wp/ul:126+21;+2×106WP/ul+ASA:118+28. EugPPP+l/P showed lower lysis area.Col induced more decrease of lysis area in euc with WP.ASA did not modify this effect.UK and SK produced higher lysis area only in euoPPP.No difference was observed between high and low doses of Col-effect upon WP.Combined treatment of eucPPP+WP+Col, with UK and SK showed:(mm2):UK-treated eugPPP+2×106WP/ul+Col(29ug/ml):134+25;+ASA and Col(20ug/ml):115+65;+Col(2uc/ml):157+50;+ASA and Col(2uo/ml):133+49; SK-treated eupPPP+2×106WP/ul:+Col(20uo/ml):144+49;+ASA and Col(20ug/ml):128+ 60;+Co1(2ug/ml):173+66;+ASA and Col(2ug/ml):142+36.Col (20ug/ml) produced slight lower lysis area of UK and SK-treated eugPPP+WP. (p:ns). ASA did not modify this effect.Col (2uc/ml) did not produce changes in lysis area of UK and SK-treated eupPPP +WP. ASA produced slight lower lysis area(p:ns).Conclusion: high dosis of Col could release anti UK,anti SK and intrinsic PA-inhibitors from platelets;low dosis of Col could only release fntrinsic PA-inhibi tors. It suggests that anti UK and anti SK release might be triggered by stronger stimuli than intrinsic PA inhibitors.ASA could not inhibit any inhibitors release.We must consider that PA-inhibi tors could be released by different metabolic pathways other than cyclooxygenase pathway.
3
Frasson, Antônio Luiz, Martina Lichtenfels, Ana Beatriz Falcone, Carolina Malhone, and Isabela Miranda. "COMPLICATIONS FOLLOWING 1001 NIPPLESPARING MASTECTOMIES: A BRAZILIAN COHORT." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1018.
Abstract:
Introduction: Nipple-sparing mastectomy (NSM) is a conservative mastectomy approach for breast cancer with oncological safety and good aesthetic satisfaction; however, many surgeons still have concerns about complication rates, especially nipple-areolar complex (NAC) necrosis. Objective: The aim of this study was to analyze the complication rates of 1001 NSM performed in a Brazilian cohort. Methods: Between January 2004 and August 2020, we evaluated 534 patients who underwent 1001 NSMs. All patients were operated by the same surgeon; the data were retrospectively evaluated by the medical chart and the patient’s follow-up was updated during the appointments. Results: The majority of indications for NSM were for breast cancer treatment (78%), followed by bilateral risk-reducing mastectomy (BRRM) (18.7%) and contralateral prophylactic mastectomy (3.3%). In total, 416 patients underwent therapeutic NSM, 85.3% for primary tumor treatment, 9.2% presented recurrence of a previous breast cancer, and 5.5% had compromised margins after previous breast-conserving surgery (BCS). Bilateral NSM was performed in 367 (88.2%) patients and unilateral surgery in 49 (11.8%) patients. Among the 100 patients who underwent BRRM, 27% had a previous breast cancer and 55% presented a genetic mutation in highly penetrant genes. Breast reconstruction was performed using silicon prosthetic implants for 91.8%, tissue expander for only 6.8% of patients, and for 1.4% of patients we do not have the data. In the 1001 NSM performed, we observed 4.4% of overall complications, including 1.1% of hematoma needing operation, 1.5% of infection, 1% of partial, and 0.2% of total nipple necrosis. Patients with previous breast cancer treated with BCS and radiotherapy had higher complication rates (21%) than in patients with no previous breast cancer treatment (6.4%), and patients >50 years old presented twofold more chance of having postoperative complications than patients <50 years old. Conclusion: We observed an overall postoperative complication rate of 4.4% and low nipple necrosis in 1001 NSM performed by the same surgeon. Older age and previous breast cancer history might be risk factors for increased complication rates following this procedure.
4
Демидова, Т. Ю., К. Г. Лобанова, and А. С. Кочина. "КЛИНИЧЕСКИЕ И ЛАБОРАТОРНЫЕ ОСОБЕННОСТИ ПАЦИЕНТОВ С САХАРНЫМ ДИАБЕТОМ 2 ТИПА, ГОСПИТАЛИЗИРОВАННЫХ В ЦЕНТР СПАСЕНИЯ КОНЕЧНОСТЕЙ В 2019-2020 ГГ." In X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-100.
Abstract:
Поражение нижних конечностей (НК) при сахарном диабете (СД) является частой причиной ампутации,
что приводит к значительному снижению качества жизни пациентов. Несмотря на широкий спектр совре-
менных методов лечения СД, прогрессивный рост количества ампутаций у данных пациентов является
актуальной проблемой.
ЦЕЛЬ: изучить клинико-лабораторные характеристики пациентов центра спасения конечностей (ЦСК)
с сахарным диабетом 2 типа (СД2).
МАТЕРИАЛЫ И МЕТОДЫ: проведен ретроспективный анализ 729 историй болезни пациентов, имею-
щих СД2 и госпитализированных в ЦСК ГБУЗ ГКБ им. В.П. Демихова в период с 2019 по 2020 гг.
РЕЗУЛЬТАТЫ: всего в анализ вошло 729 пациентов. Медиана возраста – 66,0 лет [59,0; 73,0]. У 50,89%
(n=371) пациентов стаж СД2 более 10 лет. Средний ИМТ составил 31,82±0,43 (95% ДИ 30,96-32,67).
Наиболее частой сопутствующей патологией являлась артериальная гипертензия (АГ) – 89,57% (n=653).
У 63,24% (n=461) пациентов имелась ИБС, из них у 19,62% (n=143) был инфаркт миокарда в анамнезе.
У 16,87% (n=123) наблюдалось острое нарушение мозгового кровообращения, у 44,31% (n=323) – хрони-
ческая болезнь почек (ХБП).
Медиана гликированного гемоглобина (HbA1c) составляла 7,8% [6,7; 9,1]. Медиана гликемии –
9,9 [7,2; 13,8] ммоль/л.
На инсулинотерапии находились 75,99% (n=554) пациентов, из них 14,9% получали только инсулин
(n=83), а 85,01% (n=471) – базальный инсулин и пероральные сахароснижающие препараты (ПССП). Только
ПССП получали 14,95% (n=109) пациентов. 14,13% (n=103) получали метформин, 6,31% (n=46) – ингиби-
торы дипептидилпептидазы-4 (иДПП-4), 0,41% (n=3) – агонисты глюкагоноподобного пептида (аГПП-1),
3,70% (n=27) – ингибиторы натрий-глюкозного ко-транспортера (иНГЛТ-2), 16,46% (n=120) – препараты
сульфонилмочевины. Лечение статинами получали 38,59% пациентов (n=225). Среди имевших АГ терапия
ингибиторами ренин-ангиотензин-альдостероновой системы была назначена 79,46% (n=472) пациентам,
блокаторами кальциевых каналов – 20,55% (n=128).
При поступлении у 72,7% пациентов (n=530) был диагностирован СДС. У 27,2% (n=199) – облитериру-
ющий атеросклероз артерий НК, из них у 66% (n=133) – критическая ишемия НК. У 26% пациентов с СДС
(n=244) имела место гангрена, у 34,5% (n=183) – язва, у 23,9% (n=127) – флегмона, у 9,05% (n=48) – абсцесс,
остеомиелит встречался у 11,8 (n=63) пациентов данной группы.
В отделении 15,5% (n=113) пациентам провели реваскуляризацию, 14,4% (n=105) было проведено стен-
тирование, 1,1% (n=8) – шунтирование. Ампутация НК была выполнена 51% пациентов (n=372), из них 9,95%
(n=37) – высокая ампутация, 90,05% (n=335) – низкая ампутация. Среди пациентов с СДС только местное
лечение получили 33,5% (n=244), антибактериальную терапию получали 7,2% пациентов (n=53). Выписаны
с улучшением 98,5% (n=718) пациентов, летальность стала исходом госпитализации в 1,5% случаев (n=11).
ВЫВОДЫ: большинство пациентов ЦСК с СД2, госпитализированных в 2019-2020 г., были старше 60 лет
(68,86% (n=502)), имели ожирение (64,14% (n=127)), а также атеросклеротические сердечно-сосудистые за-
болевания (АГ – 89,57% (n=653), ИБС – 63,24% (n=461), ОНМК в анамнезе – 16,87% (=123)). У 50,89% (n=371)
пациентов стаж СД2 составлял более 10 лет, у 44,31% (n=323) имелась ХБП. Исходом 51% (n=372) госпита-
лизаций стала ампутация НК, что требует более тщательного подхода к профилактике и своевременной
диагностике поражения НК у пациентов с СД.
5
Pereira, Douglas Alves, Fabiano Marques Rosa, Larissa Araújo Leal Reis, Sonaide Faria Ferreira Marques, and Lucas Edel Donato. "ANÁLISE RETROSPECTIVA DE LEISHMANIOSE VISCERAL HUMANA E CANINA EM TERESINA DE GOIÁS, GOIÁS, BRASIL DE 2007 A 2021." In II Congresso Brasileiro de Parasitologia Humana On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbrapah/24.
Abstract:
Introdução: A Leishmaniose Visceral (LV) trata-se de uma zoonose negligenciada, causada pelo protozoário do gênero Leishmania, considerada um grande problema de saúde pública em diferentes países, podendo ser fatal. Objetivo: Desse modo, o objetivo deste estudo foi analisar retrospectivamente a casuística de Leishmaniose Visceral Humana (LVH) e Leishmaniose Visceral Canina (LVC) no município de Teresina de Goiás entre os anos de 2007 a 2021. Material e métodos: Os dados foram obtidos por meio do banco de dados do Sistema de Informação de Agravos de Notificação (SINAN), do Ministério da Saúde (MS), Instituto Brasileiro de Geografia e Estatística (IBGE) e da Coordenação Estadual de Zoonoses do estado de Goiás. Na análise estatística, somente os casos do município de Teresina do Goiás foram compilados. Utilizou-se o programa EpiInfoTM 7 para execução dos cálculos. O município de Teresina de Goiás possui uma população estimada de 3.583 habitantes de acordo com a estimativa do IBGE de 2021, durante o período analisado foram diagnosticadas 19 pessoas infectadas com LVH, sendo uma média de 2 indivíduos por ano, sem nenhum caso de óbito. A maior prevalência foi em 2014 com seis indivíduos infectados. Não foram reportados casos para no período de 2007 a 2012. Estimou-se na última campanha antirrábica no município uma população canina de 783 animais no ano de 2020. Durante o período avaliado foram diagnosticados 373 cães infectados, uma média de 27 casos/ano, com uma taxa de mais de 48% animais positivos, ou seja, quase metade da população canina. Resultado: Assim como nos humanos, os casos de LVC foi mais prevalente no ano de 2014, com 88 casos confirmados, não sendo reportado nenhum caso para os anos de 2007 a 2013. No ano de 2021 coleiras a base de Deltametrina a 4% foram incorporadas ao Programa de Vigilância e Controle da Leishmaniose Visceral (PVC-LV) do MS como ferramenta adicional no controle da doença e no estado de Goiás apenas dois municípios foram contemplados, sendo Teresina de Goiás um deles. Os resultados desta campanha serão divulgados quando em momento oportuno. Conclusão: Informações sobre os aspectos da cadeia epidemiológica e população afetada por essa doença se faz necessário para estabelecer medidas profiláticas efetivas.
6
Zhou, Yifeng, Paul Ponomaryov, Cristina Mazza, and Igor Pioro. "Investigation of Thermal Efficiency of Generic Pressure-Channel Reactors With Steam Reheat." In 2016 24th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/icone24-60442.
Abstract:
Currently, i.e., in 2016, 4361 nuclear-power reactors operate in the world. 96.6% of these reactors are water-cooled (373 reactors (280 PWRs, 78 BWRs and 15 LGRs are cooled with light water and 48 reactors — PHWRs are cooled with heavy water. 15% of all water-cooled reactors are pressure-channel or pressure-tube design, the rest — pressure-vessel design. All current NPPs with water-cooled reactors have relatively low thermal efficiencies within 30–36% compared to that of current NPPs with AGRs (42%) and SFR (40%) and compared to that of modern advanced thermal power plants: combined-cycle plants (up to 62%) and supercritical-pressure coal-fired plants (up to 55%). Therefore, it is very important to propose ways of improvement of thermal efficiency for this largest group of nuclear-power reactors. It should be noted that among six Generation-IV nuclear-reactor concepts one concept is a SCWR, which might reach thermal efficiencies within the range of 45–50% and even beyond. However, this concept has been never tested, and the most difficult problem on the way of implementation of this type of reactor is the reliability of materials at supercritical pressures and temperatures, very aggressive reactor coolant – supercritical water, and high neutron flux. Up till now, no experiments on behavior of various core materials at these conditions have been reported so far in the open literature. As an interim way of thermal-efficiency improvement for water-cooled NPPs nuclear steam reheat can be considered. However, this way is more appropriate only for pressure-channel reactors, for example, CANDU-type or PHWRs. Moreover, in the 60’s and 70’s, Russia, the USA and some other countries have developed and implemented the nuclear steam reheat in subcritical-pressure experimental boiling reactors. Therefore, an objective of the current paper is to summarize this experience and to estimate effect of a number of parameters on thermal efficiencies of a generic pressure-channel reactors with nuclear steam reheat. For this purpose the DE-TOP program has been used.
7
Коротина, М. А., И. Г. Починка, and Л. Г. Стронгин. "ВЛИЯНИЕ ВАРИАБЕЛЬНОСТИ ГЛИКЕМИИ НА ПРОГНОЗ БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 2 ТИПА ВО ВРЕМЯ СТАЦИОНАРНОГО ЛЕЧЕНИЯ ОСТРОГО ИНФАРКТА МИОКАРДА." In Сборник тезисов III Конференции по лечению и диагностике сахарного диабета «Фундаментальная и клиническая диабетология в 21 веке: от теории к практике». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/diaconfiii25-26.05.23-49.
Abstract:
ЦЕЛЬ: оценить влияние вариабельности гликемии у больных сахарным диабетом 2 типа (СД2) во время
стационарного лечения по поводу острого инфаркта миокарда (ОИМ) на прогноз.
МАТЕРИАЛЫ И МЕТОДЫ: в одноцентровое исследование включались больные СД2, госпитализиро-
ванные в Региональный сосудистый центр «Городской клинической больницы №13» г. Нижнего Новгорода
по поводу ОИМ, подвергнутые чрескожному коронарному вмешательству (ЧКВ) за период с января по ав-
густ 2021 года. Всего включен 161 пациент. Средний возраст по группе составил 66±9 лет. Медиана длитель-
ности СД2 - 7 [1; 10] лет. Медиана количества измерений гликемии в течение госпитализации составила
21 [14; 29] раз. Гликемический контроль оценивался по показателям средней гликемии, стандартному от-
клонению (SD), коэффициенту вариации (Coefficient of Variation, CV), который определялся как отношение
SD гликемии к показателю средней гликемии в течение госпитализации. Под низкой вариабельностью
гликемии понимали утвержденное рекомендациями целевое значение CV ≤36% Отдалённые исходы
оценивались через 12 месяцев после выписки из стационара. Статистическая обработка проводилась
в программе Statistica 10.0.
РЕЗУЛЬТАТЫ: летальные исходы в исследуемой когорте зафиксированы в 11 случаях (7%). В течение
12 месяцев после выписки наступили еще 12 смертельных исходов (8%), то есть за весь период наблюдения
23 случая. Выжившие пациенты имели лучшие показатели средней гликемии 9,4±1,7 vs 12,1±2,5 ммоль/л
(p<0,001), SD гликемии 2,9±1,1 vs 4,2±1,5 ммоль/л (p< 0,001), CV 29,9±9 vs 36,3±14,2% (p=0,01, t-тест). Среди
пациентов с благоприятным исходом низкую вариабельность (CV≤36%) во время стационарного этапа
лечения ОИМ имели 107 (78%) против 11 (48%) умерших, (p=0,009, χ2 Pearson). При проведении много-
факторного анализа CV≤36% достоверно ассоциируется со снижением риска наступления сердечно-со-
судистой смерти в течение 12 месяцев после выписки по поводу ОИМ (ОР 0,29; 95% ДИ 0,09-0,89, р=0,03,
Cox regression).
ВЫВОДЫ: у больных СД2 во время стационарного лечения по поводу ОИМ низкая вариабельность
гликемии (СV≤36%) достоверно ассоциируется со снижением риска наступления летального исхода в те-
чение года после выписки.
Reports on the topic "363.738 498":
1
Wersal, Ryan, Bradley Sartain, Kurt Getsinger, John Madsen, John Skogerboe, Justin Nawrocki, Robert Richardson, and Morgan Sternberg. Improving chemical control of nonnative aquatic plants in run-of-the-river reservoirs. Engineer Research and Development Center (U.S.), March 2024. http://dx.doi.org/10.21079/11681/48350.
Abstract:
Current dam discharge patterns in Noxon Rapids Reservoir reduce concentration and exposure times (CET) of herbicides used for aquatic plant management. Herbicide applications during periods of low dam discharge may increase herbicide CETs and improve efficacy. Applications of rhodamine WT dye were monitored under peak (736 to 765 m³ s⁻¹) and minimum (1.4 to 2.8 m³ s⁻¹) dam discharge patterns to quantify water-exchange processes. Whole-plot dye half-life under minimal discharge was 33 h, a 15-fold increase compared with the dye treatment during peak discharge. Triclopyr concentrations measured during minimum discharge within the treated plot ranged from 214 ± 25 to 1,243 ± 36 μgL⁻¹ from 0 to 48 h after treatment (HAT), respectively. Endothall concentrations measured during minimum discharge in the same plot ranged from 164 ± 78 to 2,195 ± 1,043 μgL⁻¹ from 0 to 48 HAT, respectively. Eurasian watermilfoil (Myriophyllum spicatum L.) occurrence in the treatment plot was 66%, 8%, and 14% during pretreatment, 5 wk after treatment (WAT), and 52 WAT, respectively. Myriophyllum spicatum occurrence in the nontreated plot was 68%, 71%, and 83% during pre-treatment, 5 WAT, and 52 WAT, respectively. Curlyleaf pondweed (Potamogeton crispus L.) occurrence in the treatment plot was 29%, 0%, and 97% during pretreatment, 5 WAT, and 52 WAT, respectively. Potamogeton crispus increased from 24% to 83% at 0 WAT to 52 WAT, respectively, in the nontreated plot. Native species richness declined from 3.3 species per point to 2.1 in the treatment plot in the year of treatment but returned to pretreatment numbers by 52 WAT. Native species richness did not change during the study in the nontreated reference plot. Herbicide applications during periods of low flow can increase CETs and improve control, whereas applications during times of high-water flow would shorten CETs and could result in reduced treatment efficacy.
2
Heard, Helen. Consumer Handwashing Tracker. Food Standards Agency, August 2022. http://dx.doi.org/10.46756/sci.fsa.wiy863.
Abstract:
Between April 2020 and January 2022, the Food Standards Agency (FSA) commissioned a quarterly survey on consumer handwashing. Key findings from this survey are: Across all waves of the handwashing tracker, participants were most likely to report washing their hands with soap and warm water. However, the proportion who reported handwashing with soap and warm water ‘always’ or ‘most of the time’ declined over time (79% April 2020, compared to 68% in January 2022). Most participants reported washing their hands for between 20 and 24 seconds across all waves. However, the proportion who reported this significantly declined over time (was 35% in April 2020, down to 27% in January 2022). Over time, there was a significant decrease in the proportion of participants who reported ‘always’ washing their hands in the following scenarios inside the home: before cooking/preparing food (72% in April 2020, 62% in January 2022) before eating (48% in April 2020, 42% in January 2022) after handling rubbish (73% in April 2020, 65% in January 2022) when arriving home, after a trip outside of the home (55% in April 2020, 47% in January 2022) Reported handwashing after contact with animals (including pets) remained broadly stable over time. On average, across all waves, 36% of participants with a pet reported washing their hands ‘always’ after contact with animals, (whilst 26% reported doing this ‘most of the time’, 30% reported doing this ‘sometimes’ and 7% reported ‘never’ washing their hands after contact with animals). Over time, there was a significant decrease in the proportion of participants who reported ‘always’ washing their hands in the following scenarios outside of the home: when eating a picnic (35% in July 2020, 29% in January 2022) when consuming a takeaway outside of the home (35% in July 2020, 30% in January 2022) Since a peak in October 2020 (43%), the proportion of participants who reported ‘always’ washing their hands after blowing their nose, sneezing or coughing into their hands gradually declined and was significantly lower in January 2022 (35%). The proportion of participants who reported ‘always’ washing their hands after using the toilet also declined over time. In April 2020 87% of participants reported ‘always’ washing their hands after using the toilet, decreasing significantly to 80% in January 2022. Across all waves, most participants reported carrying and using hand sanitising gel as a hand washing alternative in a range of scenarios, but the proportion who reported doing this declined over time. For example: 55% of participants reported using hand sanitising gel after using public transport in October 2020, declining significantly to 44% in January 2022 54% of participants reported using hand sanitising gel when attending a social event in October 2020, declining significantly to 45% January 2022.
3
Hall, Linnea, Peter Larramendy, Lena Lee, and Annie Little. Landbird monitoring 2020 annual report: Channel Islands National Park. National Park Service, 2023. http://dx.doi.org/10.36967/2301088.
Abstract:
The National Park Service (NPS) began monitoring landbirds at Channel Islands National Park in 1993 as part of its long-term inventory and monitoring program. The park?s landbird monitoring later became part of the NPS Inventory and Monitoring Division?s Mediterranean Coast Network long-term monitoring programs. Consequently, landbird monitoring has been conducted in the park during every breeding season since 1993. In this report, we summarize data collected during the 2020 breeding season. Landbird monitoring was conducted between 1 April and 30 June 2020. Using distance-based sampling methods in a standardized protocol, birds were counted on 7 of 10 permanent line transects (70%) (2 of 3 on Santa Barbara Island, 1 of 1 on East Anacapa Island, and 4 of 5 on San Miguel Island). Two transects were not sampled in 2020 because of nesting California Brown Pelicans (Pelecanus occidentalis) on Santa Barbara Island (i.e., Canyons Transect) and reduced person hours and unfavorable winds on San Miguel Island (i.e., San Miguel Hill Transect). For point counts, 225 of 338 (67%) permanent stations were counted (i.e., 30 of 33 points on Santa Barbara Island, 8 of 8 on East Anacapa Island, 100 of 112 on Santa Cruz Island, 40 of 40 on San Miguel Island, and 47 of 145 on Santa Rosa Island). The 8 Prisoners? Cove points were not counted in 2020. Three points were not counted on Santa Barbara Island due to nesting pelicans: these points and the transect were also not counted in 2016?2019 to avoid disturbing breeding pelicans. Other points (i.e., on east Santa Cruz Island and Santa Rosa Island) were not counted due in large part to the global COVID-19 pandemic. Traveling to and from the park was only granted to essential NPS staff for the majority of the landbird season. Fifty-one bird species were counted from points and transects across all of the islands in 2020; 39 of these are breeding species on the island. Parkwide, the 10 most commonly detected breeding landbirds in 2020 were, in descending order: Horned Lark, Spotted Towhee, Song Sparrow, White-crowned Sparrow, Western Meadowlark, Orange-crowned Warbler, Bewick?s Wren, Island Scrub-Jay, House Finch, and Common Raven. On East Anacapa Island, 26 landbird species have been counted since 1993; 5 species were counted in 2020. No new transient species were detected in 2020; 10 transient or visiting species (nonbreeding, native species recorded only once or twice during surveys) have been counted on the island overall since 1993. On Santa Barbara Island, 49 landbird species have been counted since 1993; 15 species were counted in 2020. The highest number of Horned Lark since 1993 were counted in 2020 (n = 451). Warbling Vireo was a new transient species counted in 2020 on Santa Barbara; 30 transient or visiting species have been counted on the island since 1993. On Santa Cruz Island, 74 landbird species have been counted since 2013; 34 species were counted in 2020. Bullock?s Oriole was a new transient species counted in 2020 on Santa Cruz; 21 transient or visiting species have been counted on this island since 2013. On San Miguel Island, 69 landbird species have been counted since 1993; 14 were counted in 2020. No transient species were counted in 2020; 34 transient or visiting species have been counted on the island since 1993. On Santa Rosa Island, 75 landbird species have been counted since 1994; 26 were detected in 2020. Rose-breasted Grosbeak was a new transient species counted in 2020 on Santa Rosa Island; 30 transient or visiting species have been counted on the island since 1994. Across all the 5 islands, 3 transient or visiting bird species were newly counted in 2020, for a total of 77 such species counted since NPS monitoring began on the islands. Nonnative and invasive birds were counted on only 1 of the 5 islands in 2020: 4 European Starlings on Santa Rosa Island. However, anecdotal sightings of nonnative species occurred much more frequently (i.e., outside of the point and transect counts), and were made on all islands except Anacapa in 2020. The highest numbers of nonnative species detections occurred on Santa Cruz Island, with 33 detections of Eurasian Collared Dove (primarily at the Main Ranch area in the Central Valley), 15 detections of Brown-headed Cowbird (primarily at Scorpion Harbor), and 15 detections of European Starling (primarily at the Main Ranch and Scorpion Harbor). House Sparrows were observed fewer times, but on all islands except Anacapa; cowbirds occurred on all islands except Anacapa and San Miguel; and Rock Pigeon occurred on Santa Barbara and Santa Cruz Islands. In 2020, despite the COVID-19 pandemic, 67% of all points and 77% of all transects were counted among the 5 islands. Santa Rosa received the lightest sampling of points (32%), due to the difficulty of getting observers onto the island. Even with diminished sampling, species richness (number of species) values fell in predictable patterns: richness was greatest on the larger islands (75 on Santa Rosa, 73 on Santa Cruz) and least on the smallest islands (26 on Anacapa, 48 on Santa Barbara). We continue to recommend that nonnative invasive species, such as European Starlings on Santa Rosa Island, be removed before their numbers become harder to manage. Also, because Distance analyses assist statistically with evaluations of trends, we continue to recommend that a trend analysis using program DISTANCE, or newer hierarchical distance analyses, should be used after the 2020 season to assess 5-year trends in breeding species? numbers following the 2015 trend analysis conducted by Coonan and Dye (2016).