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Academic literature on the topic '1998 h-663'

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Published: 25 July 2024

Last updated: 31 July 2024

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Journal articles on the topic "1998 h-663"

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Kehoe, S. H., G. V. Krishnaveni, S. R. Veena, J. C. Hill, C. Osmond, Kiran, P. Coakley, S. C. Karat, and C. H. D. Fall. "Birth size and physical activity in a cohort of Indian children aged 6–10 years." Journal of Developmental Origins of Health and Disease 3, no. 4 (April 3, 2012): 245–52. http://dx.doi.org/10.1017/s2040174412000189.

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There is evidence of a reduction in children's physical activity in India in the last decade. Our objective was to assess whether size and body composition at birth are associated with physical activity in school-aged children. Children from a prospective observational cohort study born in Mysore, South India between 1997 and 1998 (n = 663) had neonatal anthropometric measurements made within 72 h of delivery [weight, mid-upper arm circumference (MUAC), chest, abdomen and head circumference, crown–heel, crown–buttock and leg length, triceps and subscapular skinfolds]. At 6–10 years, children (n = 449) were asked to wear AM7164 or GT1M Actigraph accelerometers for 7 days. Body composition was measured within 6 months of activity monitoring. Arm muscle area at birth and time of activity monitoring was calculated from MUAC and skinfold measurements.Activity outcome measures were: mean accelerometer counts per minute (cpm); counts per day and proportion of time spent in moderate and vigorous activity. The mean (s.d.) number of days with ⩾500 min of recorded accelerometer data was 7.0 (1.1). Linear regression models showed no significant associations between any of the neonatal anthropometric measures and the activity variables. Body fat percentage at 7.5 years was negatively associated with all activity variables (B = −4.69, CI: −7.31, −2.07 for mean cpm).In conclusion, this study showed no associations between body size and skinfold thickness at birth and objectively measured physical activity in childhood.

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Boomgaard, Peter, John Robert Shepherd, Bernice Jong Boers, Michael Hitchcock, Dwight Y. King, Audrey R. Kahin, Han Knapen, et al. "Book Reviews." Bijdragen tot de taal-, land- en volkenkunde / Journal of the Humanities and Social Sciences of Southeast Asia 152, no. 3 (1996): 483–508. http://dx.doi.org/10.1163/22134379-90003009.

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- Peter Boomgaard, John Robert Shepherd, Marriage and mandatory abortion among the 17th-century Siraya. Arlington: American Anthropological Association, 1995, iv + 99 pp. [American Ethnological Society Monograph Series 6.] - Bernice de Jong Boers, Michael Hitchcock, Islam and identity in Eastern Indonesia. Hull: The University of Hull Press, 1996, ix + 208 pp. - Dwight Y. King, Audrey R. Kahin, Subversion as foreign policy; The secret Eisenhower and Dulles debacle in Indonesia. New York: The New Press, 1995, 230 + 88 pp., George McT. Kahin (eds.) - Han Knapen, Harold Brookfield, In place of the forest; Environmental and socio-economic transformation in Borneo and the eastern Malay peninsula. Tokyo, New York, Paris: United Nations University Press, 1995, xiv + 310 pp. [UNU Studies on Critical Environmental Regions.], Lesley Potter, Yvonne Byron (eds.) - Niels Mulder, E. Paul Durrenberger, State power and culture in Thailand. New Haven: Yale University, Southeast Asia Studies, 1996, vii + 200 pp. [Monograph 43.] - Peter Pels, Margaret J. Wiener, Visible and invisible realms; Power, magic and colonial conquest in Bali. Chicago: University of Chicago Press, xiv + 445 pp. - Marie-Odette Scalliet, Annabel Teh Gallop, Early views of Indonesia; Drawings from the British Library. Pemandangan Indonesia di masa lampau; Seni gambar dari British Library. London: The British Library, Jakarta: Yayasan Lontar, 1995, 128 pp., 86 ill., 39 pl. - Cornelia M.I. van der Sluys, Marina Roseman, Healing sounds from the Malaysian rain forest; Temiar music and medicine. Berkeley, Los Angeles: University of California Press, 1993, xvii + 233 pp. - Cornelia M.I. van der Sluys, John D. Leary, Violence and the dream people; The Orang Asli in the Malayan emergency, 1948-1960. Athens, Ohio: Ohio University, Center for International Studies, 1995, xxiii + 238 pp. [Monographs in International Studies, Southeast Asia Series 95.] - H. Steinhauer, Darrell T. Tryon, Comparative Austronesian Dictionary; An introduction to Austronesian studies, Berlin, New York: Mouton de Gruyter, 1995, Part I, Fascicle I: xxviii pp + p.1-666; Fascicle II: xix pp + p.667-1197; Part II: xviii + 749 pp; Part III: xviii + 739 pp; Part IV: xviii + 767 pp. [Trends in Linguistics, Documentation 10 (Werner Winter and Richard A. Rhodes, eds).]

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Bojarska, Joanna, Waldemar Maniukiewicz, Lesław Sieroń, Andrzej Fruziński, Piotr Kopczacki, Krzysztof Walczyński, and Milan Remko. "Novel pseudopolymorph of the active metabolite of perindopril." Acta Crystallographica Section C Crystal Structure Communications 68, no. 9 (August 1, 2012): o341—o343. http://dx.doi.org/10.1107/s0108270112032349.

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The dimethyl sulfoxide hemisolvate of perindoprilat [systematic name: (1S)-2-((S)-{1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}azaniumyl)pentanoate dimethyl sulfoxide hemisolvate], C17H28N2O5·0.5C2H6OS, an active metabolite of perindopril, has been synthesized, structurally characterized by single-crystal X-ray diffraction and compared with its ethanol disolvate analogue [Pascardet al.(1991).J. Med. Chem.34, 663–669]. Both compounds crystallize in the orthorhombicP212121space group in the same zwitterionic form, with a protonated alanine N atom and an anionic carboxylate group at then-alkyl chain. The three structural units present in the unit cell (two zwitterions and the solvent molecule) are held together by a rich system of O—H...O, N—H...O and C—H...O hydrogen-bond contacts.

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Сычев, Константин Владимирович, Олег Рауфович Бадрутдинов, Рамзи Низамович Низамов, Руслан Рустамович Гайнуллин, and Фарит Хабуллович Калимуллин. "АДАПТИВНЫЙ ОТВЕТ БЕЛЫХ МЫШЕЙ И ИХ ПОТОМКОВ НА ХРОНИЧЕСКОЕ ПОСТУПЛЕНИЕ В ОРГАНИЗМ МАЛЫХ ДОЗ ЭКОТОКСИКАНТОВ." Российский журнал прикладной экологии, no. 3 (September 30, 2022): 50–62. http://dx.doi.org/10.24852/2411-7374.2022.3.51.63.

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Проведен анализ морфологического и функционального состояния ряда важнейших систем организма экспериментальных животных (белых беспородных мышей) и их потомства на фоне длительного регулярного поступления в организм продуктов, содержащих токсические агенты в виде продуктов разложения химических соединений (радиолиза). Моделирование экологического воздействия на организм было осуществлено путем длительного регулярного кормления животных и их потомков зерном озимой пшеницs, которое было подвергнуто гамма-облучению в дозе 400 Гр с 1-10-суточным хранением после облучения. У подвергнутых воздействию животных изучали развитие адаптивной реакции системы крови, регуляции и активности ферментов антиоксидантной защиты (состояние прооксидантно-антиоксидантной системы ПРОАС), репродуктивной системы, нестабильности генома и формирование адаптаций к используемому токсическому фактору. Исследования показали, что у животных и их потомства первого поколения (F1) существенных изменений в системе крови и других исследуемых системах не обнаружено. Однако, в соответствии с данными, полученными в ходе дальнейшего эксперимента, у животных второго поколения (F2), получавших в рационе облученное зерно с 1-суточным сроком хранения выявляются отклонения гематологических показателей, уменьшение относительной массы внутренних органов, увеличение содержания РБФ-продуктов с одновременным снижением активности антиоксидантного фермента супероксиддисмутазы и повышением процессов мутагенеза. Включение в рацион потомков второго поколения (F2) антимутагенного препарата (активной кормовой добавки, содержащей в своем составе пропионовокислые бактерии) привело к снижению выраженности гемотоксического, метаболического и мутагенетического процессов, а также способствовало адаптации организма к экотоксическому фактору. Список литературы Руководство по краткосрочным тестам для выявления мутагенных и канцерогенных химических веществ: гигиенические критерии оценки состояния окружающей среды. Женева: ВОЗ, 1989. 219 с. Патент № 2731521 Российская Федерация С1 МПК G01N 33/53 (2006.01), А 61К 9/44 (2006.01). Способ диагностики радиационных поражений организма и способ получения противолучевого антительного бентонитового препарата для диагностики радиационных поражений организма: №2019110695: заявл. 10.04.2019: опубл. 03.09.2020 / Низамов Р.Н. 11 с. Adler I.D. Cytogenetic tests in mammals // Mutagenecity testing: a practical approach. Oxford: IRL Press, 1985. P. 275–306. Baverstock K. Radiation-induced genomic instability: a paradigm-breaking phenomenon and its relevance to environmentally induced cancer // Mutation response. 2000. V. 454. P. 89‒109. Bulkley G. The role of oxygen free radicals in human disease processes // Surgery. 1993. V. 94. P. 407‒411. Chauhan P.S., Aravindakshan M., Sundaram A. Studies on dominant lethal mutations in third generation rats reared on an irradiated diet // International journal of radiation biology. 1975, V. 28, №3. P. 215‒223. Chopra V.L. Lethal and mutagenic effects of irradiated medium on E. coli // Mutation research. 1969. V. 8. P. 25-33. Coney H.M. Development of quarantine systems for host fruits of the medfly // Horticultural science. 1983. V. 18. P. 45‒47. Cousin F.J. Assessment of the probiotic potential of a dairy product fermented by Propionibacterium freudenreichii in piglets // Journal of agricultural and food chemistry. 2012. V. 60, №32. P. 7917‒7927. Delincee H. Recent advances in the radiation chemistry of proteins // Recent advances in food irradiation, Amsterdam: Elsevier Biomedical, 1983. P. 129‒147. Diehl J.F. Safety of irradiated food. New York: Marsel Dekker, 1990. 464 p. Escobar J., Rubio M., Lissi E. Sod and catalase inactivation by singlet oxygen and peroxyl radicals // Free radical biology & medicine. 1996. V. 20, №3. P. 285‒290. FAO codex general standard for irradiated foods and recommended international code of practice for the operation of radiation facilities used for the treatment of food. Rome: FAO, 1984. Fridovich I. Superoxide anion radical (O2), superoxide dismutases, and related matters // Journal of biological chemistry. 1997. V. 272, iss. 30. P. 18515‒18517. https://DOI.org/10.1074/jbc.272.30.18515. 15. Kader AA. Potential applications of ionizing radiation in postharvest handing of fresh fruits and vegetables // Food technology. 1986. V. 40. P. 117‒121. Kesavan P.C., Swaminathan M.S. Cytotoxic and mutagenic effects of irradiated substrate and food material // Radiation botany. 1971. V. 11. P. 253‒281. https://doi.org/10.1016/S0033-7560(71)90017-2. Kuzin A.M., Kopylov V.A., Vagabova M.E. On the role played by radiotoxins in stimulation of the growth and development of irradiation seeds // Stimulation newsletters. 1976. №9. P. 27‒31. Lee M.S., Yu M., Kim K.Y. Functional validation of rare human genetic variants involved in homologous recombination using Saccharomyces cerevisiae // PLoS ONE. 2015. V. 10, №5. e0124152. https://doi.org/10.1371/journal.pone.0127578. Little J.B. Radiation-induced genomic instability // Journal of radiation biology. 1998. V. 6. P. 663‒671. Meild L., Blay G.L., Thierry A. Safety assessment of dairy microorganisms: Propionibacterium and Bifidobacterium // International journal of food microbiology. 2008. V. 126, №3. P. 316‒320. https://doi.org/10.1016/j.ijfoodmicro.2007.08.019. Moy J.H. Radiation disinfestation of food and agricultural products // Proceedings of an International Conference held in Honolulu. University of Hawaii at Manoa, 1985. P. 332‒336 Nawar WW. Volatiles from food irradiation // Food reviews international. 1986. V. 2. P. 45‒78. https://doi.org/10.1080/87559128609540788. Palmer A.K., Newman A.J., Heywood R., Barry D.H., Edwards F.P., Worden A.N. The administration of monosodium l-glutamate to neonatal and pregnant rhesus monkeys // Toxicology. 1973. V. 1. P. 197‒204. https://doi.org/10.1016/0300-483X(73)90006-1. Poonam, Pophaly S.D., Tomar S.K., De S., Singh R. Multifaceted attributes of dairy propionibacteria: a review // World journal of microbiology and biotechnology. 2012. V. 28, №11. P. 3081‒3095. DOI:10.1007/s11274-012-1117-z Porter G., Festing M. A comparison between irradiated and autoclaved diets for breeding mice, with observations on palatability // Laboratory animals. 1970. V. 4(2). P. 203‒213. DOI: 10.1258/002367770781071590 Reddi O.S., Reddy P.P., Ebenezer D.N., Naidu N.V. Lack of genetic and cytogenetic effects in mice fed on irradiated wheat // International journal of radiation biology and related studies in physics, chemistry and medicine. 1977. V. 31(6). P. 589‒601. https://doi.org/10.1080/09553007714550681. Skoneczna A., Kaniak A., Skoneczny M. Genetic instability in budding and fission yeast sources and mechanisms // FEMS microbiology reviews. 1973. V. 2. P. 1713‒1722. https://doi.org/10.1093/femsre/fuv028 Vijayalaxmi J.P. Cytogenetic studies in monkeys fed irradiated wheat // Toxicology. 1978. V. 9. P. 181‒184. DOI: 10.1016/0300-483x(78)90043-4. Vorobjeva L.I., Iljasova O.V., Khodjaev E.V., Ponomareva G.M., Varioukhina S.V. Inhibition of induced mutagenesis in Salmonella typhimurium by the protein of Propionibacterium freudenreichii subsp. Shermanii // Anaerobe. 2001. V. 7. P. 37‒44. https://doi.org/10.1006/anae.2000.0365. Vorobjeva L.I., Khodjaev E.V., Cherdinceva T.A. Antimutagenic and reactivative activities of dairy propionibacteria // Lait. 1995. V. 75, №4‒5 P. 473‒487. https://DOI.org/10.1051/lait:19954-537. Vorobjeva L.I., Khodjaev E.Y., Vorobjeva N.V. Propionic acid bacteria as probiotics // Microbial ecology in health and disease. 2008. V. 20. P. 109‒112. https://doi.org/10.1080/08910600801994954. Yao Z., Jones J., Kohrt H., Strober S. Selective resistance of CD44hi T cells to p53-dependent cell death results in persistence of immunologic memory after total body irradiation // Journal of immunology. 2011. V. 187 (8). P. 4100‒4108. https://doi.org/10.4049/jimmunol.1101141. Zhu J., Pavelka N., Bradford W.D., Rancati G., Li R. Karyotypic determinants of chromosome instability in aneuploid budding yeast // PLoS Genetics. 2012. V. 8 (5). e1002719. DOI: 10.1371/journal.pgen.1002719.

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Kirk, Anne, Martin Entz, Stephen Fox, and Mario Tenuta. "Mycorrhizal colonization, P uptake and yield of older and modern wheats under organic management." Canadian Journal of Plant Science 91, no. 4 (July 2011): 663–67. http://dx.doi.org/10.4141/cjps10186.

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Kirk, A. P., Entz, M. H., Fox, S. L. and Tenuta, M. 2011. Mycorrhizal colonization, P uptake and yield of older and modern wheats under organic management. Can. J. Plant Sci. 91: 663–667. Arbuscular mycorrhizal fungi (AMF) are important for plant nutrient uptake, and mycorrhizal dependence varies between wheat genotypes. Cultivar selection under fertilized conditions may have reduced mycorrhizal associations in modern cultivars. This study investigated AMF colonization, tissue P and grain yield of five modern (post 1990) and five older (pre 1970) spring wheat cultivars over 4 site-years in Manitoba. Older cultivars actually had significantly lower AMF colonization and grain yield than modern cultivars, but no tissue P concentration differences were observed. The two highest yielding lines were released after 2004, and one of these (FBC Dylan) was selected for suitability in organic farming systems.

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Kirkpatrick, David T., Yuh-Hwa Wang, Margaret Dominska, Jack D. Griffith, and Thomas D. Petes. "Control of Meiotic Recombination and Gene Expression in Yeast by a Simple Repetitive DNA Sequence That Excludes Nucleosomes." Molecular and Cellular Biology 19, no. 11 (November 1, 1999): 7661–71. http://dx.doi.org/10.1128/mcb.19.11.7661.

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ABSTRACT Tandem repeats of the pentanucleotide 5′-CCGNN (where N indicates any base) were previously shown to exclude nucleosomes in vitro (Y.-H. Wang and J. D. Griffith, Proc. Natl. Acad. Sci. USA 93:8863–8867, 1996). To determine the in vivo effects of these sequences, we replaced the upstream regulatory sequences of the HIS4 gene ofSaccharomyces cerevisiae with either 12 or 48 tandem copies of CCGNN. Both tracts activated HIS4 transcription. We found that (CCGNN)12 tracts elevated meiotic recombination (hot spot activity), whereas the (CCGNN)48 tract repressed recombination (cold spot activity). In addition, a “pure” tract of (CCGAT)12 activated both transcription and meiotic recombination. We suggest that the cold spot activity of the (CCGNN)48 tract is related to the phenomenon of the suppressive interactions of adjacent hot spots previously described in yeast (Q.-Q. Fan, F. Xu, and T. D. Petes, Mol. Cell. Biol. 15:1679–1688, 1995; Q.-Q. Fan, F. Xu, M. A. White, and T. D. Petes, Genetics 145:661–670, 1997; T.-C. Wu and M. Lichten, Genetics 140:55–66, 1995; L. Xu and N. Kleckner, EMBO J. 16:5115–5128, 1995).

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Bojarska, Joanna, Waldemar Maniukiewicz, Lesław Sieroń, Piotr Kopczacki, Krzysztof Walczyński, and Milan Remko. "Perindoprilat monohydrate." Acta Crystallographica Section C Crystal Structure Communications 68, no. 11 (October 18, 2012): o443—o446. http://dx.doi.org/10.1107/s0108270112041583.

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The title compound [systematic name: (1S)-2-((S)-{1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}azaniumyl)pentanoate monohydrate], C17H28N2O5·H2O, (I)·H2O, the active metabolite of the antihypertensive and cardiovascular drug perindopril, was obtained during polymorphism screening of perindoprilat. It crystallizes in the chiral orthorhombic space groupP212121, the same as the previously reported ethanol disolvate [Pascard, Guilhem, Vincent, Remond, Portevin & Laubie (1991).J. Med. Chem.34, 663–669] and dimethyl sulfoxide hemisolvate [Bojarska, Maniukiewicz, Sieroń, Fruziński, Kopczacki, Walczyński & Remko (2012).Acta Cryst.C68, o341–o343]. The asymmetric unit of (I)·H2O contains one independent perindoprilat zwitterion and one water molecule. These interactviastrong hydrogen bonds to give a cyclicR22(7) synthon, which provides a rigid molecular conformation. The geometric parameters of all three forms are similar. The conformations of the perhydroindole group are almost identical, but then-alkyl chain has conformational freedom. A three-dimensional hydrogen-bonding network of O—H...O and N—H...O interactions is observed in the crystal structure of (I)·H2O, similar to the other two solvates, but because of the presence of different solvents the three crystal structures have diverse packing motifs. All three solvatomorphs are additionally stabilized by nonclassical weak C—H...O contacts.

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Lurie, Andrew J., Mark V. Mai, Martin S. Tallman, June McCoy, and Charles L. Bennett. "2006 RADAR Report Card on Conversion Rates from Accelerated FDA Approval to Regular FDA Approval for Drugs Used To Treat Hematologic Malignancies: Policy Changes Continue To Be Needed." Blood 108, no. 11 (November 16, 2006): 3318. http://dx.doi.org/10.1182/blood.v108.11.3318.3318.

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Abstract Background: At ASH 2004 and 2005, we reported < 20% rates of from accelerated approval (AA) to regular approval (RA) for drugs used to treat hematologic malignancies (HMs). The FDA convened Oncologic Drug Advisory Committee (ODAC) meetings with sponsors of these drugs in 2003 and 2005 outlining recommendations for completion of subpart H trials. Congressmen Markey and Hinchey have raised concern over low rates of completion of subpart H studies for all AA drugs. The Research on Adverse Drug Events and Reports (RADAR) project reviewed the current status of subpart H commitments for all cancer drugs that received AA prior to 2005. Methods: NDAs and supplements for new uses from the FDA, package inserts, and literature reviews were reviewed. Results: Of 19 cancer drugs receiving AA prior to 2005, conversion to RA has occurred for 2 of 9 drugs for HMs and 8 of 11 drugs for solid tumors (STs) (22% vs 73%, p<0.05). Subpart H studies have been ongoing for a median of 5 years for AA drugs for HMs; however, for ST drugs, these studies were completed in a median of 2.5 years. Of 7 subpart H studies reviewed at the 2005 ODAC meeting on AA, subpart H evaluations continue for all 4 for HMs versus 1 of 3 for STs. HMs are characterized by lower rates of target populations, most having > 25,000 newly diagnosed patients annually (25% vs 78%). Recruitment targets are smaller for AA studies for HMs (median, 82 vs 295 patients) and subpart H studies (median, 295 vs 535). Conclusions: Rates of conversion from AA to RA remain poor for drugs for hematologic malignancies but not for solid tumors drugs. In spite of ODAC meetings and two congressional inquiries, little progress ahs been made towards completing these trials. RADAR continues to urge policy makers to modify the AA process for drugs used to treat hematologic malignancies. Hematologic malignancy drugs receiving AA prior to 2005 and current status of subpart studies Drug AA Indication Pts in AA trial design AA year Target # of pts in Subpart H study RA Year Imatinib mesylate CML 1027 2001 1027 2003 Bortezomib MM 202 2003 669 2005 Denileukin difitox* CTCL** 71 1999 195 Pending Liposomal cytarabine* Lymphomatous meningitis** 33 1999 195 Pending Gemtuzumab ozogamicin* AML** 142 2000 342 Pending Alemtuzumab* B-Cell Chronic lymphocytic leukemia** 93 2001 197 Pending Ibritumomab tiuxetan Certain NHLs ** 230 2002 293 Pending Imatinib mesylate CML (pedatrics)** 39 2003 35 Pending Tositumomab Certain NHLs** 60 2003 N/A Pending Solid tumor cancer drugs receiving AA prior to 2005 and current status of subpart studies Drug AA Indication Pts in AA trial design AA year Target # of pts in Subpart H study RA year * Recommendations for completing trials were made at recent ODAC meetings ** Indications with >25,000 new diagnosis annually Irinotecan Colorectal 304 1996 535 1998 Docetaxel Breast 134 1996 326 1998 Capecitabine Breast 163 1998 511 2001 Temozolomide Brain 162 1999 573 2005 Liposomal Doxorubicin* Ovarian 85 1999 474 2005 Oxaliplatin Colorectal 463 2002 795 2004 Anastrozole Breast 9366 2002 6196 2005 Gefitinib Lung 221 2003 1700 2005 Liposomal Doxorubicin* Kaposi’s sarcoma** 77 1995 250 Pending Amifostine Non-small cell lung** 25 1996 366 Withdrawn Imatinib mesylate GI stromal tumors** 147 2002 946 Pending

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Boshoff, Helena I. M., and Valerie Mizrahi. "Expression of Mycobacterium smegmatisPyrazinamidase in Mycobacterium tuberculosis Confers Hypersensitivity to Pyrazinamide and Related Amides." Journal of Bacteriology 182, no. 19 (October 1, 2000): 5479–85. http://dx.doi.org/10.1128/jb.182.19.5479-5485.2000.

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ABSTRACT A pyrazinamidase (PZase)-deficient pncA mutant ofMycobacterium tuberculosis, constructed by allelic exchange, was used to investigate the effects of heterologous amidase gene expression on the susceptibility of this organism to pyrazinamide (PZA) and related amides. The mutant was highly resistant to PZA (MIC, >2,000 μg/ml), in accordance with the well-established role ofpncA in the PZA susceptibility of M. tuberculosis (A. Scorpio and Y. Zhang, Nat. Med. 2:662–667, 1996). Integration of the pzaA gene encoding the major PZase/nicotinamidase from Mycobacterium smegmatis (H. I. M. Boshoff and V. Mizrahi, J. Bacteriol. 180:5809–5814, 1998) or the M. tuberculosis pncA gene into the pncAmutant complemented its PZase/nicotinamidase defect. In bothpzaA- and pncA-complemented mutant strains, the PZase activity was detected exclusively in the cytoplasm, suggesting an intracellular localization for PzaA and PncA. ThepzaA-complemented strain was hypersensitive to PZA (MIC, ≤10 μg/ml) and nicotinamide (MIC, ≥20 μg/ml) and was also sensitive to benzamide (MIC, 20 μg/ml), unlike the wild-type andpncA-complemented mutant strains, which were highly resistant to this amide (MIC, >500 μg/ml). This finding was consistent with the observation that benzamide is hydrolyzed by PzaA but not by PncA. Overexpression of PzaA also conferred sensitivity to PZA, nicotinamide, and benzamide on M. smegmatis (MIC, 150 μg/ml in all cases) and rendered Escherichia colihypersensitive for growth at low pH.

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Wang, Lu, Robert Tepper, Joel L. Bert, Kenneth L. Pinder, Peter D. Paré, and Mitsushi Okazawa. "Mechanical properties of the tracheal mucosal membrane in the rabbit. I. Steady-state stiffness as a function of age." Journal of Applied Physiology 88, no. 3 (March 1, 2000): 1014–21. http://dx.doi.org/10.1152/jappl.2000.88.3.1014.

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Airway responsiveness is exaggerated in infancy and declines with maturation. These age-related differences (R.S. Tepper, T. Du, A. Styhler, M. Ludwig, and J.G. Martin. Am. J. Respir. Crit. Care Med. 151: 836–840, 1995; R.S. Tepper, S.J. Gunst, C.M. Doerschuk, Y. Shen, and W. Bray. J. Appl. Physiol.78: 505–512, 1995; R.S. Tepper, J. Stevens, and H. Eigen. Am. J. Respir. Crit. Care Med. 149: 678–681, 1994) could be due to changes in the smooth muscle, the lung, and/or the airway wall. Folding of the mucosal membrane can provide an elastic load (R.K. Lambert, J. Appl. Physiol. 71: 666–673, 1991), which impedes smooth muscle shortening. We hypothesized that increased stiffness of the mucosal membrane occurs during aging, causing an increased mechanical load on airway smooth muscle and a decrease in airway responsiveness. Forty female New Zealand White rabbits between 0.75 and 35 mo of age were studied. Rectangular mucosal membrane strips oriented both longitudinally and circumferentially to the long axis of the trachea were dissected, and the stress-strain relationships of each strip were tested. The results showed that the membrane was stiffer in the longitudinal than in the circumferential direction of the airway. However, there was no significant change with age in either orientation. We conclude that the mechanical properties of the airway mucosal membrane did not change during maturation and were not likely to influence age-related changes in airway responsiveness.

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Books on the topic "1998 h-663"

1

Caroline, Garland, ed. Understanding trauma: A psychoanalytical approach. London: Duckworth, 1998.

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Rules, United States Congress House Committee on. Providing for the consideration of H.R. 665, Victim Restitution Act of 1995: Report (to accompany H. Res. 60). [Washington, D.C.?: U.S. G.P.O., 1995.

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United States. Congress. House. Committee on Rules. Providing for the consideration of H.R. 665, Victim Restitution Act of 1995: Report (to accompany H. Res. 60). [Washington, D.C.?: U.S. G.P.O., 1995.

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Rules, United States Congress House Committee on. Providing for the consideration of H.R. 666, the Exclusionary Rule Reform Act of 1995: Report (to accompany H. Res. 61). [Washington, D.C.?: U.S. G.P.O., 1995.

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Rules, United States Congress House Committee on. Providing for the consideration of H.R. 668, Criminal Alien Deportation Improvements Act of 1995: Report (to accompany H. Res. 69). [Washington, D.C.?: U.S. G.P.O., 1995.

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United States. Congress. House. Committee on Rules. Providing for the consideration of H.R. 668, Criminal Alien Deportation Improvements Act of 1995: Report (to accompany H. Res. 69). [Washington, D.C.?: U.S. G.P.O., 1995.

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United States. Congress. House. Committee on Rules. Providing for the consideration of H.R. 666, the Exclusionary Rule Reform Act of 1995: Report (to accompany H. Res. 61). [Washington, D.C.?: U.S. G.P.O., 1995.

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Infrastructure, United States Congress House Committee on Transportation and. Sixteenth Annual National Peace Officers' Memorial Service: Report (to accompany H. Con. Res. 66) (including cost estimate of the Congressional Budget Office). [Washington, D.C.?: U.S. G.P.O., 1997.

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United States. Congress. House. Committee on Transportation and Infrastructure. Sixteenth Annual National Peace Officers' Memorial Service: Report (to accompany H. Con. Res. 66) (including cost estimate of the Congressional Budget Office). [Washington, D.C.?: U.S. G.P.O., 1997.

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United States. Congress. House. Committee on Transportation and Infrastructure. Sixteenth Annual National Peace Officers' Memorial Service: Report (to accompany H. Con. Res. 66) (including cost estimate of the Congressional Budget Office). [Washington, D.C.?: U.S. G.P.O., 1997.

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Book chapters on the topic "1998 h-663"

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Boening, John. "Gentlemen’s Magazine, 83 (1813), II: 460-462, 661-663. M/H No. 1996." In The Reception of Classical German Literature in England, 1760-1860, Volume 1, 531–33. Routledge, 2020. http://dx.doi.org/10.4324/9781003010500-93.

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Kirk, James. "Scotland Before The Union." In Annual Bibliography Of British And Irish History, 272–80. Oxford University PressOxford, 1991. http://dx.doi.org/10.1093/oso/9780199249176.003.0011.

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Abstract Ballantyne, John H.; Smith, Brian (eds.) Shetland documents 1195–1579 (Lerwick: Shetland Islands Council & the Shetland Times, 1999), xxii, 359p.Cowan, Edward J.; McDonald, Russell Andrew (eds.) Alba: Celtic Scotland in the middle ages(East Linton: Tuckwell, 2000), xiv, 282p.Cummins, Walter Arthur. The Picts and their symbols (Stroud: Sutton, 1999),218p.Emery, N. ‘The impact of the outside world on St Kilda:the artefact evidence’, A8, 161–66.Macdougall, Norman.‘L’Ecosse à la fin du XIIIe siècle: un royaume men-acé’, A130, 9–22.

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Tweeddale, Andrew, and Keren Tweeddale. "Privacy and Confidentiality." In Arbitration of Commercial Disputes, 349–70. Oxford University PressOxford, 2005. http://dx.doi.org/10.1093/oso/9780199265404.003.0011.

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Abstract The privacy and confidentiality of the arbitration process has traditionally been perceived as being a cornerstone of arbitration law. It has been stated that the privacy and confidentiality of arbitration is considered as being one of the main H Bagner, ‘Confidentiality—A Fundamental Principle in International Commercial Arbitration?’ (2001) 18 Journal of International Arbitration (No 2), 2003, 243–9. Cf Lew, Mistelis and Kröll, Comparative International Commercial Arbitration (2003) 660 at para 24–100 in which it is argued that until the early 1990s ‘no-one in England ever thought that arbitration was really “confidential”, as distinct from “private” ‘. See also P Neil QC, ‘Confidentiality in Arbitration’ (1996) 12 Arbitration International (No 3) 287–318, referring to Professor HR Trevor-Roper’s book Archbishop Laud 1573–1645 (1988) at 221–3, which gives details of an early arbitration case that was published. The case concerned an attempt by the English Crown to extract extra revenues from the creation of monopolies. The arbitral tribunal were asked to determine whether soap manufactured by a chartered company of soap-boilers washed whiter than soap produced by independent manufacturers. The arbitral tribunal found in favour of the chartered company of soap-boilers.

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Diggle, James. "The Manuscripts." In The Textual Tradition of Euripides’ Orestes, 5–16. Oxford University PressOxford, 1990. http://dx.doi.org/10.1093/oso/9780198147664.003.0002.

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Abstract Manuscripts dated certainly or possib y before 1261 H Jerusalem, Patriarchike Bibliotheke 36. Turyn 86–7, Matthiessen 41-2, Mastronarde 2. Facsimile: S. G. Daitz, The Jerusalem Palimpsest of Euripides. A Facsimile Edition with Commenta y (1970). Scholia (and corrigenda to the preceding work): S. G. Daitz, The Scholia in the Jerusalem Palimpsest of Euripides. A critical Edition (1979). A collation, made from photographs, was published by J. A. Spranger, CQ32 (1938) 200–2 10th–11th century. Lines 105–213, 313–412, 564–614, 716–66, 897–946, II52–1200, 1356–1556. Collated from the facsimile.

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"46 Kirchgeld, Nordelbische Ev.-Luth. Kirche. FG Hamburg, Urteil vom 2. 6. 1992 (IV 66/91 H)." In 1.1.1992–31.12.1992, 255–62. De Gruyter, 1997. http://dx.doi.org/10.1515/9783110893601-048.

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"BEDBOROUGH, D.R. & TROTT, P.E. 1979 The sensory measurement of odours by dynamic dilution. Report No LR 299 (AP). Warren Springs Laboratories, Stevenage. 13 BARTH, C.L., HILL, D.T. & POLKOWSKI, L.B. 1974 Correlating odour intensity index and odorous components in stored dairy manure. Transactions of the American Society of Agricultural Engineers 17(4), 742-4, 747. 14 SCHAEFER, J. 1977 Sampling, characterisation and analysis of malodours. Agriculture and Environment, 3(2,3), 121-128. 15 SCHAEFER, J. 1980 Development of instrumental methods for measuring odour levels in intensive livestock buildings. In: Effluents from Livestock (Gasser, J.K.R. (Ed.)). Applied Science Publishers, London pp 513-535. 16 KOWALEWSKY, H.H., SCHEV, R. & VETTER, H. 1980 Measurement of odour emissions and immissions. In: Effluents from Livestock (Gasser, J.K.R. (Ed)), Applied Science Publishers, London pp 609-626. 17 HARPER, R., BATESMITH, E.C. & LAND, D.G. 1968 Odour description and odour classification. J & A Churchill Ltd., London. 18 BELL, R.G. 1970 Fatty acid content as a measure of the odour potential of stored liquid poultry manure. Poultry Science, 49, 1126-9. 19 SOBEL, A.T. 1972 Olfactory measurement of animal manure odours. Transactions of the American Society of Agricultural Engineers. 15(4), 696-699 and 703. 20 AMOORE, J.E., VENSTROM, D. & DAVIS, A.R. 1968 Measurement of specific anosmia perceptual and motor skills 26, 143-164. 21 SPOELSTRA, S.F. (1980) Origin of objectionable odorous components in piggery wastes and the possibility of applying indicator components for studying odour development. Agriculture and Environments(3), 241-260. 22 OWENS, J.D., EVANS, M.R., THACKER, F.E., HISSETT, R. & BAINES S. 1973 Aerobic treatment of piggery waste. Water Research 7 1745-66. 23 EVANS, M.R., HISSETT, R., SMITH, M.P.W., THACKER, F.E. & WILLIAMS, A.G. (1980) Aerobic treatment of beef cattle and poultry waste compared with piggery waste. Agric. Wastes 2, 93-101." In Odour Prevention and Control of Organic Sludge and Livestock Farming, 329. CRC Press, 1986. http://dx.doi.org/10.1201/9781482286311-126.

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Conference papers on the topic "1998 h-663"

1

Poll, C. T., P. A. Kyrle, and J. Westwick. "ACTIVATION OF PROTEIN KINASE C INHIBITS THROMBIN AND FLUORIDE STIMULATED EICOSANOID PRODUCTION IN HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644633.

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Touqui et al (1986) have suggested that phosphorylation by protein kinase C of a 1ipomodulin-1 ike polypeptide extracted from platelets renders it inactive as an inhibitor of phospholipase A2. We have examined this suggestion by measuring thromboxane (Tx) B2 generation and cytosolic free calcium concentration ([Ca++]i) in stimulated, washed human platelets loaded with or without quin-2. Addition of thrombin (0.077, 0.23, 0.77, 2.3 and 7.7 nM) to control platelets produces a dose-related elevation of [Ca++]i (10±5, 50±7, 260±30, 550±25 and 1500±100 nM respectively) and generation of TxB2 (0, 9±4, 45±6, 194±10 and 375±30 pmoles/108 platelets respectively). Preincubation of platelets for 1 min with 1-oleoyl-2-acetyl-rac-glycerol (OAG, 22-198 μM), phorbol myristate acetate (PMA, 1.616 nM) or EGTA (2 mM) produces a marked inhibition of high and low dose thrombin (7.7 nM and 0.77 nM) or NaF (18 mM) induced elevation of [Ca++]i and TxB2 generation. Pretreatment of platelets with the protein kinase C inhibitor, H-7 (60 uM), prevented the inhibition of TxB2 formation induced by PMA (4.816 nM) or OAG (66-198 μM) in either thrombin (0.77 nM) or NaF (18 mM) stimulated platelets. When arachidonic acid (AA, 10 μM) is used as the stimulus, the Δ[Ca++]i is 190±15 nM and TxB2 generation is 35.9±2 pmoles/108 platelets. While pretreatment with 4.8 nM PMA obliterates the AA-induced Δ[Ca++]i and partially reduces (p< 0.05) the TxB2 generation to 27.8+3 pmoles/108 platelets. PMA and OAG pretreatment also inhibits TxB2 generation in thrombin-stimulated, non-quin-2-1oaded platelets. Thus, at least with intact, agonist- and NaF-stimulated platelets, activation of protein kinase C inhibits eicosanoid production.We thank the British Heart Foundation and Ciba-Geigy USA for financial support.

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