Academic literature on the topic '1926-2024'
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Journal articles on the topic "1926-2024"
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Kochanowicz, Jerzy Eugeniusz. "Respektowanie potencjału rozwojowego uczniów i refleksja nad własnym doświadczeniem – bycie nauczycielem i wychowawcą według Stanisława Dunina-Borkowskiego (1864–1934)." Studia Paedagogica Ignatiana 27, no. 2 (June 24, 2024): 39–53. http://dx.doi.org/10.12775/spi.2024.2.002.
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W 2024 roku mija 160. rocznica urodzin i 90. rocznica śmierci ks. Stanisława Dunina-Borkowskiego SJ, cenionego w krajach niemieckojęzycznych filozofa, nauczyciela, wychowawcy i autora poczytnych prac poświęconych wychowaniu. Myśl pedagogiczna tego jezuity, urodzonego we wpływowej polskiej rodzinie szlacheckiej spod Lwowa, nie jest szerzej znana w Polsce. Celem artykułu jest zaprezentowanie wybranych wątków pedeutologii Stanisława Dunina-Borkowskiego na podstawie analizy jego pedagogicznej autobiografii wydanej w 1926 roku. Autor, posługując się metodą analizy dokumentów osobistych, skoncentrował się na podkreślanym przez Stanisława Dunina-Borkowskiego osobotwórczym znaczeniu autorytetów edukacyjnych dla bycia nauczycielem, na jego predylekcji do jednostek ponadprzeciętnych przygotowywanych do bycia liderami życia społecznego oraz na postulowanym przez niego poszanowaniu potencjału rozwojowego wychowanków, które pozostaje do dzisiaj trwałym dziedzictwem europejskiej myśli pedagogicznej przełomu XIX i XX wieku.
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Alex, Dr Jincy, Dr Rejula F, Dr Mali G. Nair, and Dr Sambath K. "Management of extraoral draining sinus of odontogenic origin: A case report." International Journal of Applied Dental Sciences 10, no. 2 (January 1, 2024): 81–84. http://dx.doi.org/10.22271/oral.2024.v10.i2b.1926.
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Ramos Cardenas, Edith Stephany, Soledad Jackeline Zegarra Ugarte, Lourdes Lacuta Sapacayo, and Juana Victoria Bustinza Vargas. "Influencia de los factores socioculturales en la violencia contra la mujer en las usuarias del programa social juntos del Distrito de Cabana – 2023." Revista de Climatología 24 (May 2, 2024): 1926–38. http://dx.doi.org/10.59427/rcli/2024/v24cs.1926-1938.
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La investigación tuvo como objetivo determinar la influencia de los factores socioculturales en la violencia contra la mujer. El tipo de investigación fue la básica o teórica, con enfoque cuantitativo de alcance explicativo, diseño no experimental, corte transversal, con el método hipotético – deductivo. La población estuvo constituida por 123 usuarias del programa social JUNTOS, se utilizó la muestra no probabilística, se trabajó con las 123 usuarias por decisión de los investigadores. Para la recolección de datos se utilizó la técnica de la encuesta y como instrumento el cuestionario; así mismo, se validó la hipótesis a través de la Chi – Cuadrada. El resultado principal a la que arribo la investigación es que los factores socioculturales influyen significativamente en la violencia contra la mujer en las usuarias del programa social JUNTOS del distrito de Cabana – 2023, bajo un valor de xc 2 (12,916 > 5,9915) con 3 grados de libertad, significancia de vp (0.000) probabilidad menor a (α = 0.05), con un nivel de confianza del 95%, se demuestra que los factores socioculturales influyen significativamente en la violencia contra la mujer, presentando mayor influencia en los roles de género y el machismo. En conclusión se identificó que los roles de género arraigados y el machismo juegan un papel destacado en la perpetuación de la violencia contra las mujeres en esta comunidad. Estos resultados subrayan la importancia de abordar las normas culturales y sociales que sustentan la violencia de género, y destacan la necesidad de intervenciones específicas dirigidas a cambiar estas percepciones y comportamientos en aras de promover relaciones más igualitarias y libres de violencia.
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Hájek, Michal, Tomáš Peterka, Petra Hájková, Dirk Hinterlang, Harald Zechmeister, and Milan Chytrý. "Proposal (36) to conserve the name Philonotidion seriatae Hinterlang 1992 for the species-poor, bryophyte-dominated, non-calcareous arctic-alpine spring vegetation of Europe." Vegetation Classification and Survey 5 (March 1, 2024): 11–15. http://dx.doi.org/10.3897/vcs.103154.
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According to the International Code of Phytosociological Nomenclature, a younger name of a syntaxon may be conserved against its older name to improve the stability of the nomenclature and avoid misunderstandings in scientific communication. Here, we propose conserving the name Philonotidion seriataeHinterlang 1992 for arctic-alpine, bryophyte-dominated, non-calcareous spring vegetation against the names Cardamino-MontionBraun-Blanquet 1925, Cardamino-MontionBraun-Blanquet 1926, and MontionMaas 1959. In current vegetation classification systems, the two name-giving taxa of Cardamino-Montion no longer indicate the character of the vegetation corresponding to the nomenclatural type of this alliance and are instead characteristic of other currently distinguished alliances. Maintaining the oldest name Cardamino-Montion in strict adherence to the Code would be a source of errors. In the current vegetation classification systems, two similar but counter-intuitive names would then have to be used: Cardamino-Montion for arctic-alpine springs (although the name-giving taxa are more indicative of montane springs) and Epilobio nutantis-Montion for montane springs (although the name-giving taxon Epilobium nutans is indicative of arctic-alpine vegetation). Hence, there is a risk that the name Cardamino-Montion may gradually become ambiguous. We also propose conserving the name Philonotidion seriatae against Mniobryo-Epilobion hornemanniiNordhagen 1943 to prevent confusion in case of a merger of these alliances. (36) Philonotidion seriataeHinterlang 1992 Typus: Cratoneuro-PhilonotidetumGeissler 1976 (holotypus) (=) Cardamino-MontionBraun-Blanquet 1925 Typus: Bryetum schleicheriBraun-Blanquet 1925 [≡ Montio fontanae-Bryetum schleicheriBraun-Blanquet 1925 nom. corr. et invers. (alternative name)] (holotypus) (=) Cardamino-MontionBraun-Blanquet 1926 nom. superfl. [≡ Cardamino-MontionBraun-Blanquet 1925] (=) Mniobryo-Epilobion hornemanniiNordhagen 1943 Typus: Mniobryo-Epilobietum hornemanniiNordhagen 1943 (lectotypus selected by Zechmeister & Mucina 1994) (=) MontionMaas 1959 nom. superfl. [≡ Cardamino-MontionBraun-Blanquet 1925] Taxonomic reference: Euro+Med PlantBase (http://europlusmed.org; accessed 4 January 2024)
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Thatikonda, Venu, Kaja Kostyrko, Sabine Jurado, Simone Lieb, Melanie Hinkel, Donat Alpar, Oliver Bergner, Astrid Jeschko, Mark Pearson, and Marco H. Hofmann. "Abstract 1926: MRAS the forgotten member of the GTPase superfamily plays a role in KRASG12Ci resistance." Cancer Research 84, no. 6_Supplement (March 22, 2024): 1926. http://dx.doi.org/10.1158/1538-7445.am2024-1926.
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Abstract KRASG12C inhibitors have achieved impressive results in the clinic. However, intrinsic or acquired resistance to therapy invariably develops leading to disease progression in most treated patients. Emerging pre-clinical and clinical evidence points to multiple mechanisms being responsible for resistance to KRASG12C inhibitors, including receptor tyrosine kinase (RTK) activation, KRASG12C amplification, activation of alternative signaling pathways including PI3K, mTOR, YAP/TAZ, acquisition of KRAS mutations that would preclude compound binding (e.g. R68S, Y96C/D, H95D/Q/R), conversion of the G12C codon mutation, and additional activating KRAS mutations (G13D, Q61H). In the clinic, many of the described mutations were detected at low frequency, some patients displayed multiple mutations and in 40% of patients no potential driving mutations were identified. It is therefore likely that other non-genetic alterations are also involved in resistance to KRASG12Ci monotherapy. Here, we used preclinical models of KRASG12C non-small cell lung cancer (NSCLC) and colorectal cancer (CRC) to study intrinsic and acquired resistance to KRASG12C inhibitors. Increased expression of the RAS superfamily gene MRAS was observed in most KRASG12C-naïve tumor cells upon treatment with a KRASG12C inhibitors. In line with this, we observed an increase of MRAS-GTP levels in cells treated with KRASG12Ci in vitro. Interestingly, the increase in active MRAS did not lead to concomitant upregulation of MAPK signaling. Long term treatment with adagrasib was used for generating in vitro and in vivo KRASG12C models with acquired resistance to KRASG12Ci. A strong increase in MRAS expression was observed under these conditions, that surpassed the levels seen with short term treatment in naïve models. This data suggests that activation of MRAS-SHOC2-PP1C complex may play a role in compensating for the KRASG12C-driven signaling in both the intrinsic and acquired resistance setting. Knockdown of SHOC2 to baseline levels resulted in re-sensitization to KRASG12Ci monotherapy and to the effects of combinations in adagrasib-resistant NCI-H358 NSCLC cells. Pathway suppression was deepened by combining adagrasib with either a SOS1i (e.g. BI-3406) or SHP2i (e.g. TNO155) resulting in enhanced anti-tumor effects observed in the KRASG12Ci-resistant models. Our findings underscore the role of MRAS in acquired resistance in KRASG12Ci and the potential to overcome this with vertical pathway combinations, such as SOS1i or SHP2i. Citation Format: Venu Thatikonda, Kaja Kostyrko, Sabine Jurado, Simone Lieb, Melanie Hinkel, Donat Alpar, Oliver Bergner, Astrid Jeschko, Mark Pearson, Marco H. Hofmann. MRAS the forgotten member of the GTPase superfamily plays a role in KRASG12Ci resistance [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 1926.
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ROMERO-RINCON, JUAN, and SANTIAGO ALVEAR. "On the identity of the enigmatic millipede genus Inodesmus Cook, 1896 (Polydesmida: Haplodesmidae)." Zootaxa 5437, no. 3 (April 15, 2024): 433–40. http://dx.doi.org/10.11646/zootaxa.5437.3.8.
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The identity of Inodesmus Cook, 1896 and its single species, Inodesmus jamaicensis Cook, 1896, has been a mystery for decades. This species was described from a Jamaican cave but not only did the repository of the type material remain unknown, but also the types were believed to be lost. Here we redescribe the species and designate a lectotype and a paralectotype from the newly found type material. The genus Agathodesmus Silvestri, 1910 from Australia and New Caledonia is presented as a new junior subjective synonym of Inodesmus. Besides I. jamaicensis, the genus Inodesmus includes 23 species: I. adelphus (Mesibov, 2013) comb. nov.; I. aenigmaticus (Mesibov, 2013) comb. nov.; I. agnus (Mesibov, 2013) comb. nov.; I. anici (Mesibov, 2013) comb. nov.; I. baccatus (Carl, 1926) comb. nov.; I. bonang (Mesibov, 2013) comb. nov.; I. bucculentus (Jeekel, 1986) comb. nov.; I. carorum (Mesibov, 2013) comb. nov.; I. chandleri (Mesibov, 2013) comb. nov.; I. gayundah (Mesibov, 2013) comb. nov.; I. hahnensis (Mesibov, 2013) comb. nov.; I. johnsi (Mesibov, 2009) comb. nov.; I. kerensis (Mesibov, 2013) comb. nov.; I. kirrama (Mesibov, 2013) comb. nov.; I. millaa (Mesibov, 2013) comb. nov.; I. morwellensis (Mesibov, 2013) comb. nov.; I. parapholeus (Mesibov, 2013) comb. nov.; I. quintanus (Mesibov, 2013) comb. nov.; I. sagma (Mesibov, 2013) comb. nov.; I. steeli (Silvestri, 1910) comb. nov.; I. summus (Mesibov, 2013) comb. nov.; I. urbanus (Romero-Rincon & Douch, 2024) comb. nov.; I. yuccabinensis (Mesibov, 2013) comb. nov. The bizarre disjunct distribution of Inodesmus is briefly discussed.
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Baskaran, G., and A. R. May. "Boson bloom." Journal of Physics B: Atomic, Molecular and Optical Physics 57, no. 14 (June 17, 2024): 142001. http://dx.doi.org/10.1088/1361-6455/ad3ff4.
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Abstract The year 2024 marks the 100th anniversary of the first article on Bose statistics. Bose breathed life into the Planck distribution of radiation by a microscopic derivation (Bose 1924 Z. Phys. 26 178), adding a new insight, namely indistinguishability into the then evolving quantum theory. Einstein recognized the importance of this article and got it published. Using Bose statistics Einstein wrote an article on the theory (Einstein 1924 Sutzungsber. Preuss. Akad. Wiss Phys.-Math Kl. 261) of an ideal Bose gas and Bose–Einstein condensation. The groundbreaking discovery of Bose, an unveiling of a secret of quantum mechanics, continues to reverberate after a century. Bose’s paper is considered the fourth important paper in old quantum theory, following Planck’s (1900) article (Planck 1900 Verh. Disch Phys. Ges. 2 202), Einstein’s (1905) photoelectric effect (Einstein 1905 Ann. Phys., Lpz. 17 132) and Bohr’s model (1913) of the atom (Bohr 1913 London, Edinburgh Dublin Phil. Mag. J. Sci. 26 1). Dirac (1926 Proc. R. Soc. A 112 661) coined the name boson for one of the two families of indistinguishable particles, the other family being fermion. The edifice of modern quantum field theory, many-body quantum theory, quantum-information and quantum-computing are built on bosons, fermions and anyons. The ever-blooming quantum garden of bosons has photons, gluons, W-bosons, mesons, Higgs-bosons, gravitons, phonons, magnons, excitons, plasmons, polaritons and so on. We present a brief historical account of Bose’s life and his discovery, followed by a bird’s eye view of the impacts of bosons in modern science and technology: from Bose’s distribution of 3-degree background radiation reaching us in the form of cosmic microwave background from the big bang era to boson sampling, a novel quantum computing method. Bosogenesis before Baryogenesis?: And God said, Let there be light: and there was light (Genesis, 1:4)
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Whelan, Jeremy, Jane Hook, Stefan S. Bielack, Neyssa Marina, Sigbjorn Smeland, Gordana Jovic, Mark D. Krailo, et al. "EURAMOS-1 study: Recruitment, characteristics, and initial treatment of more than 2,000 patients (pts) with high-grade osteosarcoma." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 10081. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.10081.
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10081 Background: EURAMOS is a transAtlantic collaboration formed to improve survival in osteosarcoma by conducting RCTs in a clinically relevant timeframe. EURAMOS-1, the largest study conducted in this rare cancer, has completed accrual. It includes two randomized comparisons investigating treatment optimization on the basis of histological response to neoadjuvant chemotherapy. Methods: Pts ≤40yrs with resectable, high grade extremity or axial osteosarcoma were eligible for registration. All were planned for 2 cycles of neoadjuvant methotrexate, doxorubicin, cisplatin (MAP) then surgical resection of the primary tumour. Pts with complete macroscopic resection and no disease progression were eligible for randomization: [i] “good responders”, <10% viable tumor, MAP +/- 18m maintenance pegylated interferon; [ii] “poor responders”, ≥10% viable tumor, MAP vs MAPIE (MAP + ifosfamide, etoposide). Target sample size was ~1,260 pts randomized requiring ~2000 pts registered estimating a non-randomization rate of 30-35%. Results: From Apr 2005 to Dec 2011, 2,260 pts were registered and 1,332 randomized from 17 countries, 320 sites: median age 14yrs (IQR 11-17); 59% male; 50% femoral site; 23% definite/possible metastases; 92% conventional osteosarcoma (diagnostic biopsy). At Sep 2011 planned IDMC review, neoadjuvant treatment data were known for 2024 pts; 1926 (95%) completed 2 cycles pre-operative MAP with 3 treatment related deaths. 59% pts were randomized; non-consent was the most frequent reason for non-randomization. Relative to expected age-specific incidence (UK NCIN 1979-2007) there was apparent under recruiting of older pts: females ≥15yrs and all pts >19yrs, with greater under recruitment of females than males <35yrs. Pts 20-29yrs were less likely to be randomized than those aged 5-19 and ≥30 yrs, 52% vs 57-62%. Conclusions: EURAMOS-1 demonstrates that large RCTs are feasible in rare cancers with inter-continental collaboration and is a model for future trials. Neoadjuvant MAP was safe in a geographically diverse cohort. Improving clinical trial access and randomization rates for young people is still required. Multiple funders detailed at bit.ly/ymUR9w.
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Kim, Kyung-Nyun. "Dental education toward 2050 in Korea." Journal of The Korean Dental Association 62, no. 6 (June 30, 2024): 389–98. http://dx.doi.org/10.22974/jkda.2024.62.6.003.
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Modern dentistry began as a descendant of barber-surgeons. In 1728, Fauchard of France published Dentist (Le chirurgien dentiste au traité des dents), who defined the scope and nature of modern dentistry. In 1926, Gies of the United States proposed the standardization of the dental curriculum and set goals for dentist education. However, although the framework of the dental curriculum proposed by Gies was excellent, that was ahead of his time, nearly 100 years have already passed. Therefore, we would like to predict the changes in oral care in about 30 years from now in 2024, and look for clues to the direction of change in dental education in Korea accordingly.</br>Due to changes in technology, it is expected that teaching methods using virtual and augmented reality will be universally implemented in dental education. Artificial intelligence is expected to be widely applied in dental care system. The relationship between oral health and systemic health will become clearer, and the importance of preventive dentistry will be further emphasized. The use of digital dentistry and 3D printing is expected to increase, and related education is needed. The dental education system should go beyond the scope of barber dentists and consider further on periodontics and systemic health. As interest in overall health and quality of life will increase, cooperation not only between dentists but also among other professionals such as medical doctors and para-medical/dental specialists will become common and the composition of the Korean population is expected to become diverse. The importance of leadership, communication, and cultural sensitivity in clinical care should be emphasized and educated. Ethics and professionalism must be prioritized in dental care, and students must be educated to become dentists. I think it may be more efficient to focus on improving educational competences and educational content rather than revolutionary change in the curriculum.</br>However, the current society is changing rapidly, and dental medicine at the time when students currently attending dental school become active dentists, will be different from what it is now, and dental education in Korea should be provided to prepare for this.
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Allen, Isaac, Hend Hassan, Yvonne Walburga, Catherine Huntley, Lucy Loong, Tameera Rahman, Beth Torr, et al. "Abstract 7321: Second primary cancer risks following breast cancer in BRCA1/2 pathogenic variant carriers." Cancer Research 84, no. 6_Supplement (March 22, 2024): 7321. http://dx.doi.org/10.1158/1538-7445.am2024-7321.
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Abstract Background: Second primary cancer (SPC) risk estimates in breast cancer (BC) survivors carrying germline BRCA1/2 pathogenic variants (PVs) remain uncertain. We estimated relative and absolute SPC risks following BC in BRCA1/2 PV carriers using genetic testing laboratory data in England, linked for the first time to population-scale electronic health records data from the National Disease Registration Service and Hospital Episode Statistics. Material and methods: The cohort contained 27,154 women diagnosed with primary BC and tested for germline BRCA1/2 PVs between 1995-2019. Follow-up began at the latest of the genetic test dates and one year following the BC diagnosis and continued until the first SPC diagnosis, death, migration, relevant surgery, and the end of 2020, whichever came first. We estimated overall and site-specific standardized incidence ratios (SIRs) by comparing observed and expected SPC counts, with expected counts calculated using incidences for the general English population accounting for calendar year, SPC site, age, and gender. We stratified the SIRs by age, estrogen-receptor status, and cancer site. We further assessed associations using Cox regression adjusted for age at BC diagnosis and estrogen-receptor status of the first BC, and estimated 10-year absolute SPC risks with Kaplan-Meier analysis. Results: There were 1909 BRCA1 (138 with SPCs) and 1926 BRCA2 (101 with SPCs) PV carriers, with mean follow-up lengths of 4.2 and 4.4y and median follow-up lengths of 3.4 and 3.6y. In BRCA1 PV carriers, there were elevated contralateral BC (SIR:15.3, 95%CI:11.5-19.8), ovarian (SIR:43.3, 95%CI:30.9-58.9), non-breast and non-ovarian combined (SIR:2.23, 95%CI:1.63-2.98), colorectal (SIR:4.72, 95%CI:2.58-7.92) and uterine (SIR:3.42, 95%CI:1.25-7.44) SPC risks. In BRCA2 PV carriers, there were increased contralateral BC (SIR:7.53, 95%CI:5.33-10.3), ovarian (SIR:16.5, 95%CI:10.1-25.5), non-breast and non-ovarian (SIR:1.72, 95%CI:1.27-2.27) and pancreatic (SIR:6.57, 95%CI:2.63-13.5) SPC risks. Consistently, when we compared BC survivors carrying a BRCA1 PV to BC survivors without a PV in either gene, they were at elevated contralateral BC (HR:3.94, 95%CI:2.91-5.33), ovarian (HR:35.7, 95%CI:21.3-60.0), non-breast and non-ovarian (HR:1.53, 95%CI:1.11-2.12) and colorectal (HR:2.95, 95%CI:1.56-5.55) SPC risks, whereas BRCA2 PV carriers were at increased contralateral BC (HR:2.59, 95%CI:1.83-3.65), ovarian (HR:12.3, 95%CI:6.93-21.9) and pancreatic (HR:5.32, 95%CI:2.30-12.3) SPC risks. We estimated 10-year cumulative contralateral BC, ovarian, and non-breast and non-ovarian SPC risks of 15%, 6.3%, and 7.8% in BRCA1 PV carriers and 12%, 2.9%, and 6.2% in BRCA2 PV carriers. Conclusions: Cancer risks were increased, at combined and specific sites, following BC in BRCA1/2 PV carriers. These findings could aid the clinical management of BC survivors carrying BRCA1/2 PVs. Citation Format: Isaac Allen, Hend Hassan, Yvonne Walburga, Catherine Huntley, Lucy Loong, Tameera Rahman, Beth Torr, Andrew Bacon, Craig Knott, Sophie Jose, Sally Vernon, Margreet Lüchtenborg, Joanna Pethick, Francesco Santaniello, Shilpi Goel, Sophie Allen, Katrina Lavelle, Fiona McRonald, Diana M. Eccles, Eva Morris, Steven Hardy, Clare Turnbull, Marc Tischkowitz, Paul Pharoah, Antonis C. Antoniou. Second primary cancer risks following breast cancer in BRCA1/2 pathogenic variant carriers [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 7321.
Conference papers on the topic "1926-2024"
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Alunno, A., P. Altieri, A. Cecchini, D. Colella, M. Litterio, A. Paolucci, E. DI Ruscio, F. M. Mariani, C. Ferri, and F. Carubbi. "AB0131 NOT ALL THAT HURTS IS FIBROMYALGIA: THE CHALLENGE OF DIFFERENTIAL DIAGNOSIS IN PATIENTS WITH A PRE-EXISTING DIAGNOSIS OR A CLINICAL SUSPICION FOR FIBROMYALGIA." In EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria. BMJ Publishing Group Ltd and European League Against Rheumatism, 2024. http://dx.doi.org/10.1136/annrheumdis-2024-eular.1926.
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Zheng, Andy X., Robert Knepper, David Damm, and Yi C. Mazumdar. "Optical Digital Image Correlation for the Study of Thermal Cycling and Mechanical Fracture of Energetic Materials." In AIAA SCITECH 2024 Forum. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2024. http://dx.doi.org/10.2514/6.2024-1926.
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Purdy, William. "Anchors Aweigh, Time for Class: The First Naval ROTC Units on College Campuses, 1926–1941." In 2024 AERA Annual Meeting. Washington DC: AERA, 2024. http://dx.doi.org/10.3102/2110432.
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