Academic literature on the topic '153.3/5'

Superhydrophobic surfaces wit ordered hierarchical microstructures were prepared on copper substrates by combining thermal transfer and etching. The surface morphology, wettability, chemical composition and corrosion resistance were, respectively, characterized via scanning electron microscopy, a three-dimensional confocal microscope, contact angle measurement, X-ray diffraction, X-ray photoelectron spectroscopy, electrokinetic polarization and electrochemical impedance spectroscopy techniques. The contact angle of the obtained superhydrophobic surface is up to 153.3° with a reduction in the corrosion current density from 3.9105 × 10−5 A/cm2 to 3.5421 × 10−6 A/cm2 via the electrokinetic polarization curve test, and the maximum capacitive arc radius of the superhydrophobic surface is about 2.5 × 104 Ω cm2 via the electrochemical impedance spectroscopy test, which is two orders of magnitude higher than that of bare copper substrate, and the maximum modulus value |Z| is also two orders of magnitude higher than that of bare copper substrate, indicating that the superhydrophobic surface has better corrosion resistance. This method provides an effective etching approach toward preparing superhydrophobic surfaces with ordered microstructures.

Mixed matrix membranes (MMMs) containing zeolitic imidazolite framework-8 (ZIF-8) and UiO-66 as microporous fillers were prepared and evaluated their potential for the separation of a gas mixture produced by a methane reforming process. Hydrothermal synthesis was performed to prepare both the ZIF-8 and UiO-66 crystals, with crystal sizes ranging from 50 to 70 nm for ZIF-8 and from 200 to 300 nm for UiO-66. MMMs were prepared with 15% filler loading for both MMM (ZIF-8) and MMM (UiO-66). MMM (UiO-66) exhibited H2 permeability of 64.4 barrer and H2/CH4 selectivity of 153.3 for single gas permeation, which are more than twice the values that were exhibited by a neat polymer membrane. MMM (ZIF-8) also showed better separation properties than that of a neat polymer membrane with H2 permeability of 27.1 barrer and H2/CH4 selectivity of 123.2. When a gas mixture consisting of 78% Ar/18% H2/4% CH4 flowed into the membranes at 5 bar, the H2 purity increased to as high as 93%. However, no improvement in the mixture gas separation performance was achieved by the MMMs as compared to that of a neat polymer membrane.

Cyclooxygenase-2 (COX-2) is constitutively expressed and highly regulated in the thick ascending limb (TAL). As COX-2 inhibitors (Coxibs) increase COX-2 expression, we tested the hypothesis that a negative feedback mechanism involving PGE2 EP3 receptors regulates COX-2 expression in the TAL. Sprague-Dawley rats were treated with a Coxib [celecoxib (20 mg·kg−1·day−1) or rofecoxib (10 mg·kg−1·day−1)], with or without sulprostone (20 μg·kg−1·day−1). Sulprostone was given using two protocols, namely, previous to Coxib treatment (prevention effect; Sulp7-Coxib5 group) and 5 days after initiation of Coxib treatment (regression effect; Coxib10-Sulp5 group). Immunohistochemical and morphometric analysis revealed that the stained area for COX-2-positive TAL cells (μm2/field) increased in Coxib-treated rats (Sham: 412 ± 56.3, Coxib: 794 ± 153.3). The Coxib effect was inhibited when sulprostone was used in either the prevention (285 ± 56.9) or regression (345 ± 51.1) protocols. Western blot analysis revealed a 2.1 ± 0.3-fold increase in COX-2 protein expression in the Coxib-treated group, an effect abolished by sulprostone using either the prevention (1.2 ± 0.3-fold) or regression (0.6 ± 0.4-fold vs. control, P < 0.05) protocols. Similarly, the 6.4 ± 0.6-fold increase in COX-2 mRNA abundance induced by Coxibs ( P < 0.05) was inhibited by sulprostone; prevention: 0.9 ± 0.3-fold ( P < 0.05) and regression: 0.6 ± 0.1 ( P < 0.05). Administration of a selective EP3 receptor antagonist, L-798106, also increased the area for COX-2-stained cells, COX-2 mRNA accumulation, and protein expression in the TAL. Collectively, the data suggest that COX-2 levels are regulated by a novel negative feedback loop mediated by PGE2 acting on its EP3 receptor in the TAL.

Poorly managed medical waste produced at the health facilities are potential source of infections including occupational exposure to Hepatitis B Virus (HBV). This study evaluated the prevalence of HBV infection among healthcare workers (HCWs) in Kisumu County. We determined prevalence of HBV infections among 192 HCWs from nine purposively selected high-patient volume public hospitals in Kisumu County. A structured questionnaire was administered, and 4.0 ml of venous blood sample collected for Hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs) and total hepatitis B core antibody (anti-HBc) testing using enzyme immunoassay (EIA). Of 192 HCWs sampled, 52.1% were males and the median participants age was 34.4 years with interquartile range (IQR) of 11 (28–39) years. Most participants (44%) had worked for between 1–5 years. There was low HBV vaccine uptake with 35.9% completing the required 3 doses, while 40.6% had never been vaccinated. HBV prevalence was 18.8% (36/192), prevalence of past resolved infection was 25.5% (49/192), while 37.5% (72/192) of HCW had evidence of vaccine-derived immunity and 17.7% (34/192) were susceptible. HBV prevalence among HCW who had worked for less than one year and those who had never been vaccinated was 37.5% and 35.9% respectively. Significant risk of HBV lifetime exposure was noted among HCWs with one vaccine dose, those with no known exposure, while highest in those with knowledge on HBV transmission (aOR, 7.97; 95% CI, 2.10–153.3, p-value = 0.008). HCWs who had received ≥2 doses of HBV vaccine (aOR, 0.03; 95% CI, 0.01–0.10, p-value = <0.0001) had significant HBV protection. Duration of service was not associated with HBV among HCWs. HBV prevalence was high among HCWs from nine high patient volume public hospitals in Kisumu County. Efforts to strengthen HBV vaccination uptake and dose completion are needed to reduce HBV infections among HCWs.

Abstract. Ice fabric influences the rheology of ice, and hence the age–depth profile at ice core drilling sites. To investigate the age–depth profile to be expected of the ongoing deep ice coring at Kunlun station, Dome A, we use the depth-varying anisotropic fabric suggested by the recent polarimetric measurements around Dome A along with prescribed fabrics ranging from isotropic through girdle to single maximum in a three-dimensional, thermo-mechanically coupled full-Stokes model of a 70 × 70 km2 domain around Kunlun station. This model allows for the simulation of the near basal ice temperature and age, and ice flow around the location of the Chinese deep ice coring site. Ice fabrics and geothermal heat flux strongly affect the vertical advection and basal temperature which consequently control the age profile. Constraining modeled age–depth profiles with dated radar isochrones to 2∕3 ice depth, the surface vertical velocity, and also the spatial variability of a radar isochrones dated to 153.3 ka BP, limits the age of the deep ice at Kunlun to between 649 and 831 ka, a much smaller range than previously inferred. The simple interpretation of the polarimetric radar fabric data that we use produces best fits with a geothermal heat flux of 55 mW m−2. A heat flux of 50 mW m−2 is too low to fit the deeper radar layers, and 60 mW m−2 leads to unrealistic surface velocities. The modeled basal temperature at Kunlun reaches the pressure melting point with a basal melting rate of 2.2–2.7 mm a−1. Using the spatial distribution of basal temperatures and the best fit fabric suggests that within 400 m of Kunlun station, 1-million-year-old ice may be found 200 m above the bed, and that there are large regions where even older ice is well above the bedrock within 5–6 km of the Kunlun station.

Abstract. We use the EMAC (ECHAM/MESSy Atmospheric Chemistry) global model with the aerosol module MADE (Modal Aerosol Dynamics model for Europe, adapted for global applications) to quantify the impact of transport emissions (land transport, shipping and aviation) on the global aerosol. We consider a present-day (2000) scenario according to the CMIP5 (Climate Model Intercomparison Project Phase 5) emission data set developed in support of the IPCC (Intergovernmental Panel on Climate Change) Fifth Assessment Report. The model takes into account particle mass and number emissions: The latter are derived from mass emissions under different assumptions on the size distribution of particles emitted by the three transport sectors. Additional sensitivity experiments are performed to quantify the effects of the uncertainties behind such assumptions. The model simulations show that the impact of the transport sectors closely matches the emission patterns. Land transport is the most important source of black carbon (BC) pollution in the USA, Europe and the Arabian Peninsula, contributing up to 60–70% of the total surface-level BC concentration in these regions. Shipping contributes about 40–60% of the total aerosol sulfate surface-level concentration along the most-traveled routes of the northern Atlantic and northern Pacific oceans, with a significant impact (~ 10–20%) along the coastlines. Aviation mostly affects aerosol number, contributing about 30–40% of the particle number concentration in the northern midlatitudes' upper troposphere (7–12 km), although significant effects are also simulated at the ground, due to the emissions from landing and take-off cycles. The transport-induced perturbations to the particle number concentrations are very sensitive to the assumptions on the size distribution of emitted particles, with the largest uncertainties (about one order of magnitude) obtained for the land transport sector. The simulated climate impacts, due to aerosol direct and indirect effects, are strongest for the shipping sector, in the range of −222.0 to −153.3 mW m−2, as a consequence of the large impact of sulfate aerosol on low marine clouds and their optical properties.

BackgroundRapidly progressive interstitial lung disease (RP-ILD) is often seen in dermatomyositis patients with anti-melanoma differentiation-associated gene 5 (anti-MDA-5) antibody. They often have a poor prognosis with rapid decline in pulmonary function, leading to respiratory failure (1). Aggressive immunosuppressive therapy has been reported with improved prognosis, however; it may lead to opportunistic infections, including cytomegalovirus (CMV) or Pneumocystis pneumonia (PCP) infection (2, 3).ObjectivesThis study aimed to evaluate the effectiveness of tofacitinib (TOF) in combination with CMV and PCP prophylaxis in anti-MDA-5-positive patients.MethodsMedical records of 17 anti-MDA-5-positive RP-ILD patients enrolled during Mar 2017 to May 2021 were reviewed. RP-ILD was defined by the presence of deteriorated dyspnea, with a decrease in PaO2 levels and emerging radiographic anomalies within 4 weeks without evidence of infection (4). Chest CT was scored using Ichikado score (5). Clinical parameters including ferritin levels, white counts (WBC), Lactate dehydrogenase (LDH) levels, GAP scores (Gender, Age, and Physiology score for idiopathic pulmonary fibrosis) were recorded. Medications included cyclophosphamide (CyP), intravenous immunoglobulin (IVIG), mycophenolic acid derivatives (MPA), rituximab (RTX), and calcineurin inhibitor (CNI). Kaplan-Meier survival analysis and Log-rank test were used to evaluate one-year mortality differences (MedCalc version 19.6). The Ethics Committee approved our study (CE17038B).ResultsSix anti-MDA-5-positive RP-ILD patients were treated with tofacitinib; five had concomitant CMV prophylaxis with valganciclovir (VGCV); 4 had PCP prophylaxis with trimethoprim/sulfamethoxazole (TMP-SMX). Patients’ demographic data are shown in Table 1. The median age, clinical manifestations, laboratory data, and chest CT scores were comparable between tofacitinib and non-tofacitinib groups. Prevalence of MPA use was higher in the non-TOF group. Kaplan-Meier survival analysis (Figure 1) indicated that patients with tofacitinib treatment (p=0.001), valganciclovir (p=0.003), and TMP-SMX (p=0.028) prophylaxis exhibited better 1-year survival rates compared with those without TOF therapy, VGCV, and TMP-SMX prophylaxis.Table 1.Clinical characteristics of anti-MDA-5 antibody-positive patients with RP-ILD receiving tofacitinib vs non-tofacitinib treatment.Tofacitinib (n=6)Non-tofacitinib (n=11)p valueAge (years)58 (42.3-77)57 (50.0-62.0)0.884Female sex, n (%)2 (33.3)6 (54.5)0.620Diabetes mellitus, n (%)0 (0)5 (45.5)0.102Fever, n (%)5 (83.3)10 (90.9)1.000Mechanic’s hands, n (%)4 (66.7)5 (45.5)0.620Ferritin (n=16, ng/ml))2670.9 (719.7-4209.7)1563.5 (967.8-3169.0)0.635WBC (x1000μl)8.7 (6.5-9.9)8.7 (6.0-12.9)0.884LDH (n=16, U/l)367.0 (218.0-557.5)433.0 (331.0-625.3)0.313GAP score5 (2.5-8)5 (2-6)0.808CT score200.0 (124.2-214.2)196.7 (153.3-273.3)0.733TMP-SMX, n (%)4 (66.7)0 (0)0.006**VGCV, n (%)5 (83.3)0 (0)0.001**CyP, n (%)1 (16.7)4 (36.4)0.600IVIG, n (%)1 (16.7)6 (54.5)0.304MPA, n (%)0 (0)7 (63.6)0.035*RTX, n (%)3 (50.0)5 (45.5)1.000CNI, n (%)2 (33.3)6 (54.5)0.620Continuous variables were expressed as median (inter-quartile range).*p<0.05, **p<0.01 by Mann–Whitney U test or Fisher’s Exact test.Figure 1.ConclusionThe study demonstrated the efficacy of tofacitinib treatment in anti-MDA-5-positive RP-ILD. In addition, CMV and PCP prophylaxis appeared to improve in 1-year survival. Rheumatologists might consider TOF with prophylaxis as an option for anti-MDA-5-positive patients in daily practice.References[1]Sato S, et al. Arthritis Rheum 2009;60(7):2193-200.[2]Sekiguchi A, et al. J Dermatol 2020;47(8):876-81.[3]Sabbagh SE, et al. Rheumatology 2021;60(2):829-36.[4]Kurasawa K, et al. Rheumatology 2018;57(12):2114-19.[5]Ichikado K, et al. Radiology 2006;238(1):321-9.AcknowledgementsWe are grateful to the Biostatistics Task Force staff of Taichung Veterans General Hospital for their assistance in performing the statistical analyses and Tomoko Hasegawa for her technical assistance with the immunoassays. We also thank Dr. Wen-Nan Huang, Dr. Pin-Kuei Fu, Dr. Chia-Wei Hsieh, Dr. Yi-Hsing Chen, and Dr. Der-Yuan Chen for their help on resources and supervision.Disclosure of InterestsNone declared

Background The aim of the study was to assess the safety and glycemic outcomes with the use of a Do-It-Yourself (DIY) Hybrid Closed-Loop (HCL) system based on the AndroidAPS application in type 1 diabetes (T1D). Methods Single-center clinical trial, with 3-week run-in and 12-week study period. DIY HCL system consisted of the Dana Diabecare RS insulin pump, Dexcom G5 continuous glucose monitoring system and AndroidAPS application. Primary outcome was safety: incidences of severe hypoglycemia, diabetic ketoacidosis, time spent in glycemia <54 mg/dl. Secondary endpoints included percentage of time in range (TIR) 70–180 mg/dl, time below 70 mg/dl, HbA1c, insulin requirements, and body weight. Results In total 12 subjects (5 men, 7 women) were enrolled, mean age 31.3±6.7, 95%CI(27.7–34.9) years, mean diabetes duration 16.1±5.7, 95%CI(13.0–19.2) years. No episodes of severe hypoglycemia or ketoacidosis were observed. Percentage of time spent in glycemia below 54mg/dl was not increased. Average sensor glycemia was lower in the study period than baseline (141.1 ± 8.4, 95%CI(136.3–145.9) vs. 153.3 ± 17.9, 95%CI(143.2–163.4), mg/dl p<0.001). TIR 70–180 mg/dl was improved by 11.3%, 95%CI(2.8%-19.8%) (from 68.0 ± 12.7 to 79.3 ± 6.4%, p<0.001), without increasing hypoglycemia time. The HbA1c level decreased by -0.5%, 95%CI(-0.9%–-0.1%) (from 6.8 ± 0.5 to 6.3 ± 0.4%, p<0.001). Additionally, in the last 4 weeks of the study period participants significantly improved and showed TIR 70–180 mg/dl 82.1 ± 5.6%, 95%CI(78.9–85.3), time <54 mg/dl 0.30 (0.20–0.55)%, median 95%CI(0.1–0.7) and <70 mg/dl 1.90 (1.10–3.05)%, median 95%CI(0.7–3.2). The insulin requirement and body weight did not change in the study. Conclusions The study revealed safety of the Do-It-Yourself HCL system AndroidAPS in adults with T1D, limited to well-controlled, highly selected and closely monitored patients. The use of AndroidAPS significantly improved HbA1c, time in range and average sensor glycemia without increasing hypoglycemia. As both patients and their medical team are gaining experience using the system over time, they improve glycemic control. Trial registration German Clinical Trials Register: no. DRKS00015439; https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00015439.

e24107 Background: Capecitabine is a prodrug activated to its cytotoxic form 5-fluorouracil by thymidine phosphorylase whose active metabolites inhibit DNA synthesis by reducing thymidine production and also inhibits RNA and protein synthesis by competing with uridine triphosphate. Capecitabine is used in many types of tumors and its main reported side effects are diarrhea, hand-foot syndrome and hematologic toxicity. Methods: Retrospective analysis of a cohort of patients visited in a private hospital in Mexico City, that has a basal triglyceride profile and at least two determinations during treatment with capecitabine with or without oxaliplatin. Results: We analyzed 14 patients with a mean age of 55 years (IQR 40-73), 12 patients with colorectal cancer, 78.5% in the adjuvant setting, a half of patients with capecitabine monotherapy and the other half in combination with oxaliplatin. Comorbidities as overweight/obesity were seen in a half of the patients, diabetes in 21.4% and hypertriglyceridemia at baseline in 57.1% of patients all of them G1. The mean baseline glucose was 99.5 mg/dl (IQR 74-174), the mean baseline cholesterol was 180.8 mg/dl (IQR 85-243), the mean baseline triglycerides was 153.3 mg/dl (IQR 85-243). During capecitabine treatment a total of 85.7% of patients developed hypertriglyceridemia: G3/4 of 21.4%, G2 of 28.5%, G1 of 35.7%. No patient developed a serious complication associated with hypertriglyceridemia such as pancreatitis. There was no association between monotherapy or combination treatment with oxaliplatin, of patients with grade ≥2 hypertriglyceridemia, five received capecitabine monotherapy and two in combination with oxaliplatin. Also, no association was found among the highest levels of cholesterol, glucose, disease stage, age or body mass index. All of the 6 patients with normal baseline triglycerides developed hypertriglyceridemia 66.6% G1 and 33.3% G2. All the patients who present with hypertriglyceridemia G3/4 had baseline hypertriglyceridemia and 66.6% also diabetes. Conclusions: This analysis shows the high prevalence of hypertriglyceridemia associated with the use of capecitabine as monotherapy or combined with oxaliplatin in a Mexican cohort, with an incidence of 21.4% of hypertriglyceridemia G3/4 having the pre-existing hypertriglyceridemia and diabetes as risk factors. The cause of the worsening of the lipid profile requires more research but justify lipid profile at baseline and during the treatment with capecitabine. Due to the small size of the sample, the findings need to be confirmed with a prospective study with a larger number of patients.

نفذت الدراسة في مختبرات كلية الزراعة – جامعة الكوفة لتقييم قدرة الفطريات المحفزة لنمو النبات على انتاج الهرمونات النباتية في رواشحها وفي ظروف الحضن المتحرك Shaking incubator والساكن Static incubator ، والتي اثبتت كفاءة عالية في تحفيز نمو النباتات الملقحة بها على انتاج الهرمونات النباتية الاندول استك اسد (IAA) وحامض الجبرلين (GA3) . هدفت الدراسة الى التحري مختبريا عن قدرة عزلات محلية من الفطريات المحفزة للنمو وهي : A-7 (Aspergillus fumigatus) و A-D-1 (A. niger) فضلاً عن العزلة T-113 من الفطر (Trichoderma hamatum) ، بهدف تقدير كمية ونوعية الهرمونات المنتجة وبالتالي اعتمادها كمصدر لانتاج الهرمونين والذي بدوره يمكن ان يبحث امكانية استخدام رواشح تلك الفطريات الحاوية على الهرمونين بشكل مباشر على النبات واختبار تاثيراته في دراسات لاحقة. اظهرت نتائج الدراسة أن الفطريات الثلاث الفعالة في تحفيز وتشجيع النمو A-D-1 وA-7 وT-113 انتجت الهرمونين IAA وGA3 المحفزين لنمو النبات ، حدد الهرمون IAA من خلال محتوى راشح العزلات الفطرية المضاف إليه 1000 مايكروغرام / لتر Tryptophan كبادئ لتصنيع الهرمون في ظروف الحضن المتحرك Shaking 120 دورة / دقيقة والساكن ، وفي فترات الحضن الممتدة لـ 5 و10 و15 يوماً على التوالي في درجة حرارة 28+ 2مْ. تميز الفطر A-D-1 بأعلى متوسط لمحتوى الراشح من الهرمون حيث بلغ 153.3 ملغم / لتر تلاه الفطر A-7 بمتوسط بلغ 137.8 ملغم / لتر ، في حين سجلت العزلة الفطرية 113T- أقل متوسط بلغ 90 ملغم / لتر في ظروف الحضن المتحرك . وفيما يخص ظروف الحضن الساكن فقد ظهرت العزلة الفطرية A-7 بأعلى متوسط لمحتوى الراشح من الهرمون بلغ مقداره 1211 ملغم/لتر تلتها العزلة الفطرية A-D-1 بمتوسط بلغ 221 ملغم / لتر ، أما العزلة الفطرية 13T- فقد ظهرت بأقل متوسط بلغ 118 ملغم / لتر . أما إنتاج الهرمون GA3 ، فقد حدد من خلال محتوى راشح الفطريات في ظروف الحضن المتحرك Shaking 150 دورة / دقيقة والساكن ، وخلال فترات الحضن الممتدة لمدة 7 و14 و21 يوماً على التوالي عند درجة حرارة 28+ 2مْ ، ظهر الفطر A-7 باعلى متوسط لمحتوى الراشح من الهرمون حيث بلغ 2.018 ملغم / لتر تلاه الفطر A-D-1 بمتوسط بلغ 0.742 ملغم / لتر ، أما العزلة الفطرية T-113 فقد ظهرت باقل متوسط بلغ 0.698 ملغم / لتر بعد مرور 21 يوماً في ظروف الحضن المتحرك . أما في ظروف الحضن الساكن فقد ظهر الفطر A-7 بأعلى متوسط لمحتوى الراشح من الهرمون حيث بلغ 2.433 ملغم / لتر تلاه الفطر A-D-1 بمتوسط بلغ 0.477 ملغم / لتر ، أما العزلة الفطرية T-113 فقد ظهرت بأقل متوسط بلغ 0.443 ملغم / لتر.

The Gulf Islands National Seashore (GUIS) vegetation inventory project classified and mapped vegetation on park-owned lands within the administrative boundary and estimated thematic map accuracy quantitatively. The project began in June 2016. National Park Service (NPS) Vegetation Mapping Inventory Program provided technical guidance. The overall process included initial planning and scoping, imagery procurement, field data collection, data analysis, imagery interpretation/classification, accuracy assessment (AA), and report writing and database development. Initial planning and scoping meetings took place during May, 2016 in Ocean Springs, Mississippi where representatives gathered from GUIS, the NPS Gulf Coast Inventory and Monitoring Network, and Colorado State University. Primary imagery used for interpretation was 4-band (RGB and CIR) orthoimages from 2014 and 2016 with resolutions of 15 centimeters (cm) (Florida only) and 30 cm. Supplemental imagery with varying coverage across the study area included National Aerial Imagery Program 50 cm imagery for Mississippi (2016) and Florida (2017), 15 and 30 cm true color Digital Earth Model imagery for Mississippi (2016 and 2017), and current and historical true-color Google Earth and Bing Map imagery. National Oceanic Atmospheric Administration National Geodetic Survey 30 cm true color imagery from 2017 (post Hurricane Nate) supported remapping the Mississippi barrier islands after Hurricane Nate. The preliminary vegetation classification included 59 United States National Vegetation Classification (USNVC) associations. Existing vegetation and mapping data combined with vegetation plot data contributed to the final vegetation classification. Quantitative classification using hierarchical clustering and professional expertise was supported by vegetation data collected from 250 plots in 2016 and 29 plots in 2017 and 2018, as well as other observational data. The final vegetation classification includes 39 USNVC associations and 5 park special types; 18 forest and woodland, 7 shrubland, 17 herbaceous, and 2 sparse vegetation types were identified. The final GUIS map consists of 38 map classes. Land cover classes include four types: non-vegetated barren land / borrow pit, developed open space, developed low – high intensity, and water/ocean. Of the 34 vegetation map classes, 26 represent a single USNVC association/park special, six map classes contain two USNVC associations/park specials, and two map classes contain three USNVC associations/park specials. Forest and woodland associations had an abundance of sand pine (Pinus clausa), slash pine (Pinus elliottii), sand live oak (Quercus geminata), yaupon (Ilex vomitoria), wax myrtle (Morella cerifera), and saw palmetto (Serenoa repens). Shrubland associations supported dominant species such as eastern baccharis (Baccharis halimifolia), yaupon (Ilex vomitoria), wax myrtle (Morella cerifera), saw palmetto (Serenoa repens), and sand live oak (Quercus geminata). Herbaceous associations commonly included camphorweed (Heterotheca subaxillaris), needlegrass rush (Juncus roemerianus), bitter seabeach grass (Panicum amarum var. amarum), gulf bluestem (Schizachyrium maritimum), saltmeadow cordgrass (Spartina patens), and sea oats (Uniola paniculata). The final GUIS vegetation map consists of 1,268 polygons totaling 35,769.0 hectares (ha) or 88,387.2 acres (ac). Mean polygon size excluding water is 3.6 ha (8.9 ac). The most abundant land cover class is open water/ocean which accounts for approximately 31,437.7 ha (77,684.2 ac) or 87.9% of the total mapped area. Natural and ruderal vegetation consists of 4,176.8 ha (10,321.1 ac) or 11.6% of the total area. Within the natural and ruderal vegetation types, herbaceous types are the most extensive with 1945.1 ha (4,806.4 ac) or 46.5%, followed by forest and woodland types with 804.9 ha (1,989.0 ac) or 19.3%, sparse vegetation types with 726.9 ha (1,796.1 ac) or 17.4%, and shrubland types with 699.9 ha (1,729.5 ac) or 16.8%. Developed open space, which can include a matrix of roads, parking lots, park-like areas and campgrounds account for 153.8 ha (380.0 ac) or 0.43% of the total mapped area. Artificially non-vegetated barren land is rare and only accounts for 0.74 ha (1.82 ac) or 0.002% of the total area. We collected 701 AA samples to evaluate the thematic accuracy of the vegetation map. Final thematic accuracy, as a simple proportion of correct versus incorrect field calls, is 93.0%. Overall weighted map class accuracy is 93.6%, where the area of each map class was weighted in proportion to the percentage of total park area. This method provides more weight to larger map classes in the park. Each map class had an individual thematic accuracy goal of at least 80%. The hurricane impact area map class was the only class that fell below this target with an accuracy of 73.5%. The vegetation communities impacted by the hurricane are highly dynamic and regenerated quickly following the disturbance event, contributing to map class disagreement during the accuracy assessment phase. No other map classes fell below the 80% accuracy threshold. In addition to the vegetation polygon database and map, several products to support park resource management are provided including the vegetation classification, field key to the associations, local association descriptions, photographic database, project geodatabase, ArcGIS .mxd files for map posters, and aerial imagery acquired for the project. The project geodatabase links the spatial vegetation data layer to vegetation classification, plot photos, project boundary extent, AA points, and the PLOTS database. The geodatabase includes USNVC hierarchy tables allowing for spatial queries of data associated with a vegetation polygon or sample point. All geospatial products are projected using North American Datum 1983 (NAD83) in Universal Transverse Mercator (UTM) Zone 16 N. The final report includes methods and results, contingency tables showing AA results, field forms, species list, and a guide to imagery interpretation. These products provide useful information to assist with management of park resources and inform future management decisions. Use of standard national vegetation classification and mapping protocols facilitates effective resource stewardship by ensuring the compatibility and widespread use throughout the NPS as well as other federal and state agencies. Products support a wide variety of resource assessments, park management and planning needs. Associated information provides a structure for framing and answering critical scientific questions about vegetation communities and their relationship to environmental processes across the landscape.