Academic literature on the topic '110701 Allergy'

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Journal articles on the topic "110701 Allergy"

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Sicherer, Scott H. "Early introduction of peanut to infants at high allergic risk can reduce peanut allergy at age 5 years." Evidence Based Medicine 20, no. 6 (September 17, 2015): 204. http://dx.doi.org/10.1136/ebmed-2015-110201.

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Stayoussef, Mouna, Jihen Benmansour, Fayza A. Al-Jenaidi, Hichem B. Said, Chiheb B. Rayana, Touhami Mahjoub, and Wassim Y. Almawi. "Glutamic Acid Decarboxylase 65 and Islet Cell Antigen 512/IA-2 Autoantibodies in Relation to Human Leukocyte Antigen Class II DR and DQ Alleles and Haplotypes in Type 1 Diabetes Mellitus." Clinical and Vaccine Immunology 18, no. 6 (April 13, 2011): 990–93. http://dx.doi.org/10.1128/cvi.00073-11.

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ABSTRACTThe frequencies of autoantibodies against glutamic acid decarboxylase 65 (GAD65) and islet cell antigen (ICA) 512/IA-2 (512/IA-2) are functions of the specific human leukocyte antigen (HLA) in type 1 diabetes mellitus (T1D). We investigated the association of HLA class II (DR and DQ) alleles and haplotypes with the presence of GAD and IA-2 autoantibodies in T1D. Autoantibodies were tested in 88 Tunisian T1D patients and 112 age- and gender-matched normoglycemic control subjects by enzyme immunoassay. Among T1D patients, mean anti-GAD antibody titers were higher in theDRB1*030101allele (P< 0.001), together with theDRB1*030101/DQB1*0201(P< 0.001) andDRB1*040101/DQB1*0302(P= 0.002) haplotypes, while lower anti-GAD titers were associated with theDRB1*070101(P= 0.001) andDRB1*110101(P< 0.001) alleles andDRB1*070101/DQB1*0201(P= 0.001) andDRB1*110101/DQB1*030101(P= 0.001) haplotypes. Mean anti-IA-2 antibody titers were higher in theDRB1*040101allele (P= 0.007) andDRB1*040101/DQB1*0302(P= 0.001) haplotypes but were lower in theDRB1*110101allele (P= 0.010) and theDRB1*110101(P< 0.001) andDRB1*110101/DQB1*030101(P= 0.025) haplotypes. Multinomial regression analysis confirmed the positive association ofDRB1*030101and the negative association ofDRB1*110101andDQB1*030101, along with theDRB1*070101/DQB1*0201andDRB1*110101/DQB1*030101haplotypes, with anti-GAD levels. In contrast, only theDRB1*040101/DQB1*0302haplotype was positively associated with altered anti-IA-2 titers. Increased GAD65 and IA-2 antibody positivity is differentially associated with select HLA class II alleles and haplotypes, confirming the heterogeneous nature of T1D.
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Almawi, Wassim Y., Marc Busson, Hala Tamim, Einas M. Al-Harbi, Ramzi R. Finan, Saria F. Wakim-Ghorayeb, and Ayesha A. Motala. "HLA Class II Profile and Distribution of HLA-DRB1 and HLA-DQB1 Alleles and Haplotypes among Lebanese and Bahraini Arabs." Clinical Diagnostic Laboratory Immunology 11, no. 4 (July 2004): 770–74. http://dx.doi.org/10.1128/cdli.11.4.770-774.2004.

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ABSTRACT The gene frequencies of HLA class II alleles were studied in 95 healthy Lebanese Arab and 72 healthy Bahraini Arab subjects. Our aim was to establish the genetic relationship between Bahraini and Lebanese Arabs in terms of HLA class II gene and haplotype frequencies and to compare these results with frequencies for other countries with populations of Caucasian and non-Caucasian descent. Subjects were unrelated and of both sexes, and HLA-DRB1 and -DQB1 genotyping was done by the PCR sequence-specific primer technique. Comparative analysis of the HLA-DR and -DQ alleles revealed differences in the allelic distribution among Bahraini and Lebanese subjects. Analysis of the 25 HLA-DRB1 alleles that have been investigated showed that the DRB1*040101 and DRB1*110101 alleles were more frequent among Lebanese, whereas DRB1*030101 and DRB1*160101 alleles were more frequent among Bahrainis. Similarly, of the seven HLA-DQB1 alleles analyzed, the presence of DQB1*0201 was more frequent among Bahrainis, whereas DQB1*030101 was more frequent among Lebanese. The DRB1*160101-DQB1*050101 (0.1318 versus 0.0379%) and DRB1*030101-DQB1*0201 (0.1202 versus 0.0321%) haplotypes were more frequent among Bahrainis, while the DRB1*110101-DQB1*030101 (0.3142 versus 0.1198%) and DRB1*040101-DQB1*0302 (0.1416 versus 0.0278%) haplotypes were more frequent in Lebanese subjects. Furthermore, a high prevalence of the DRB1*040101-DRB1*110101-DQB1*0302-DQB1*030101 (12.63 versus 1.35%, P = 0.015) and the homozygous DRB1*110101-DRB1*110101-DQB1*030101-DQB1*030101 (7.37 versus 0.00%, P = 0.046) genotypes was seen among Lebanese, and DRB1*070101-DRB1*160101-DQB1*0201-DQB1*050101 (6.76 versus 0.00%, P = 0.034) was seen more frequently among Bahraini subjects. Our results underline significant differences between these two populations in HLA class II distribution, provide basic information for further studies of major histocompatibility complex heterogeneity among Arabic-speaking countries, and serve as a reference for further anthropological studies.
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Sharma, Rashmi, Ravi Deval, Vikash Priyadarshi, Shailendra N. Gaur, Ved P. Singh, and Anand B. Singh. "Indoor Fungal Concentration in the Homes of Allergic/Asthmatic Children in Delhi, India." Allergy & Rhinology 2, no. 1 (January 2011): ar.2011.2.0005. http://dx.doi.org/10.2500/ar.2011.2.0005.

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Allergy to fungi has been linked to a wide range of illnesses, including rhinitis and asthma. Therefore, exposure to fungi in home environment is an important factor for fungal allergy. The present study was aimed to investigate types of airborne fungi inside and outside the homes of asthmatic children and control subjects (nonasthmatic children). The dominant fungi were evaluated for their quantitative distribution and seasonal variation. The air samples were collected from indoors and immediate outdoors of 77 selected homes of children suffering from bronchial asthma/allergic rhinitis using Andersen volumetric air sampler. The isolated fungal genera/species were identified using reference literature, and statistical analysis of the dominant fungi was performed to study the difference in fungal concentration between indoor and immediate outdoor sites as well as in between different seasons. A total of 4423 air samples were collected from two indoor and immediate outdoor sites in a 1-year survey of 77 homes. This resulted in the isolation of an average of 110,091 and 107,070 fungal colonies per metric cube of air from indoor and outdoor sites, respectively. A total of 68 different molds were identified. Different species of Aspergillus, Alternaria, Cladosporium, and Penicillium were found to be the most prevalent fungi in Delhi homes, which constituted 88.6% of the total colonies indoors. Highest concentration was registered in autumn and winter months. Total as well as dominant fungi displayed statistically significant differences among the four seasons (p < 0.001). The largest number of isolations were the species of Aspergillus ( >40% to total colony-forming units in indoors as well as outdoors) followed by Cladosporium spp. Annual concentration of Aspergillus spp. was significantly higher (p < 0.05) inside the homes when compared with outdoors. Most of the fungi also occurred at a significantly higher (p < 0.001) rate inside the homes when compared with immediate outdoors. Asthmatic children in Delhi are exposed to a substantial concentration of mold inside their homes as well as immediate outdoor air. The considerable seasonal distributions of fungi provide valuable data for investigation of the role of fungal exposure as a risk for respiratory disorders among patients suffering from allergy or asthma in Delhi.
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Al-Harbi, Einas M., Abdul-Jabbar Abbassi, Hala Tamim, Fayza al-Jenaidi, Mariam Kooheji, Madeeha Kamal, Salwa al-Mahroos, Faisal al-Nasir, Ayesha A. Motala, and Wassim Y. Almawi. "Specific HLA-DRB and -DQB Alleles and Haplotypes Confer Disease Susceptibility or Resistance in Bahraini Type 1 Diabetes Patients." Clinical Diagnostic Laboratory Immunology 11, no. 2 (March 2004): 292–96. http://dx.doi.org/10.1128/cdli.11.2.292-296.2004.

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ABSTRACT Insofar as genetic susceptibility to type 1 diabetes is associated with HLA class II genes, with certain allelic combinations conferring disease susceptibility or resistance, this study assessed the distributions of HLA-DR and -DQ among 107 unrelated patients with type 1 diabetes and 88 healthy controls from Bahrain, all of Arab origin. The HLA-DRB and -DQB genotypes were determined by PCR-sequence-specific priming. The following alleles showed the strongest association with type 1 diabetes among patients versus controls according to their frequencies: DRB1*030101 (0.430 versus 0.097; P < 0.001), DRB1*040101 (0.243 versus 0.034; P < 0.001), DQB1*0201 (0.467 versus 0.193; P < 0.001), and DQB1*0302 (0.229 versus 0.091; P < 0.001). When the frequencies of alleles in controls were compared to those in patients, negative associations were seen for DRB1*100101 (0.085 versus 0.014; P < 0.001), DRB1*110101 (0.210 versus 0.060; P < 0.001), DQB1*030101 (0.170 versus 0.075; P = 0.006), and DQB1*050101 (0.335 versus 0.121; P < 0.001). In addition, the DRB1*030101-DQB1*0201 (70.1 versus 22.7%; P < 0.001) and DRB1*030101-DQB1*0302 (21.5 versus 0.0%; P < 0.001) genotypes were more prevalent among patients, thereby conferring disease susceptibility, whereas the DRB1*100101-DQB1*050101 (20.5 versus 2.8%; P < 0.001), DRB1*110101-DQB1*030101 (28.4 versus 8.4%; P < 0.001), and DRB1*110101-DQB1*050101 (30.7 versus 0.9%; P < 0.001) genotypes were more prevalent among controls, thus assigning a protective role. These results confirm the association of specific HLA-DR and -DQ alleles and haplotypes with type 1 diabetes and may underline several characteristics that distinguish Bahraini patients from other Caucasians patients.
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Almawi, Wassim Y., Saria F. Wakim-Ghorayeb, Mona R. Arekat, Pierre Najm, Sose H. Keleshian, Nasreen Al-Sayed, Bruno Blanchon, Hanady R. Samaha, and Noha Irani-Hakime. "Association of Selective HLA Class II Susceptibility-Conferring and Protective Haplotypes with Type 2 Diabetes in Patients from Bahrain and Lebanon." Clinical and Vaccine Immunology 13, no. 11 (September 20, 2006): 1296–98. http://dx.doi.org/10.1128/cvi.00206-06.

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ABSTRACT The association of HLA class II with type 2 diabetes (T2DM) was investigated in Bahraini and Lebanese subjects. DRB1*070101 (Lebanese and Bahraini) and DQB1*0201 (Lebanese) were susceptibility-conferring alleles, and unique susceptibility-conferring/protective haplotypes were found in both patient groups. Regression analysis confirmed that DRB1*070101-DQB1*0201 (Bahraini) and DRB1*110101-DQB1*0201 (Lebanese) were susceptibility-conferring haplotypes.
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BOOKMAN, ARTHUR. "Imaging of Arthritis and Metabolic Bone Disease." Journal of Rheumatology 38, no. 5 (May 2011): 968.1–968. http://dx.doi.org/10.3899/jrheum.110001.

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SHARIF, ROOZBEH, MARVIN J. FRITZLER, MAUREEN D. MAYES, EMILIO B. GONZALEZ, TERRY A. McNEARNEY, HILDA DRAEGER, MURRAY BARON, et al. "Anti-Fibrillarin Antibody in African American Patients with Systemic Sclerosis: Immunogenetics, Clinical Features, and Survival Analysis." Journal of Rheumatology 38, no. 8 (May 15, 2011): 1622–30. http://dx.doi.org/10.3899/jrheum.110071.

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Objective.Anti-U3-RNP, or anti-fibrillarin antibodies (AFA), are detected more frequently among African American (AA) patients with systemic sclerosis (SSc) compared to other ethnic groups and are associated with distinct clinical features. We examined the immunogenetic, clinical, and survival correlates of AFA in a large group of AA patients with SSc.Methods.Overall, 278 AA patients with SSc and 328 unaffected AA controls were enrolled from 3 North American cohorts. Clinical features, autoantibody profile, and HLA class II genotyping were determined. To compare clinical manifestations, relevant clinical features were adjusted for disease duration. Cox proportional hazards regression was used to determine the effect of AFA on survival.Results.Fifty (18.5%) AA patients had AFA. After Bonferroni correction, HLA-DRB1*08:04 was associated with AFA, compared to unaffected AA controls (OR 11.5, p < 0.0001) and AFA-negative SSc patients (OR 5.2, p = 0.0002). AFA-positive AA patients had younger age of disease onset, higher frequency of digital ulcers, diarrhea, pericarditis, higher Medsger perivascular and lower Medsger lung severity indices (p = 0.004, p = 0.014, p = 0.019, p = 0.092, p = 0.006, and p = 0.016, respectively). After adjustment for age at enrollment, AFA-positive patients did not have different survival compared to patients without AFA (p = 0.493).Conclusion.Our findings demonstrate strong association between AFA and HLA-DRB1*08:04 allele in AA patients with SSc. AA SSc patients with AFA had younger age of onset, higher frequency of digital ulcers, pericarditis and severe lower gastrointestinal involvement, but less severe lung involvement compared to AA patients without AFA. Presence of AFA did not change survival.
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BINGHAM, CLIFTON O., RIEKE ALTEN, SUSAN J. BARTLETT, VIVIAN P. BYKERK, PETER M. BROOKS, ERNEST CHOY, ROBIN CHRISTENSEN, et al. "Identifying Preliminary Domains to Detect and Measure Rheumatoid Arthritis Flares: Report of the OMERACT 10 RA Flare Workshop." Journal of Rheumatology 38, no. 8 (August 2011): 1751–58. http://dx.doi.org/10.3899/jrheum.110401.

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Background.While disease flares in rheumatoid arthritis (RA) are a recognized aspect of the disease process, there is limited formative research to describe them.Methods.The Outcome Measures in Rheumatology Clinical Trials (OMERACT) RA Flare Definition Working Group is conducting an international research project to understand the specific characteristics and impact of episodic disease worsening, or “flare,” so that outcome measures can be developed or modified to reflect this uncommonly measured, but very real and sometimes disabling RA disease feature. Patient research partners provided critical insights into the multidimensional nature of flare. The perspectives of patients and healthcare and research professionals are being integrated to ensure that any outcome measurement to detect flares fulfills the first OMERACT criteria of Truth. Through an iterative data-driven Delphi process, a preliminary list of key domains has been identified to evaluate flare.Results.At OMERACT 10, consensus was achieved identifying features of flare in addition to the existing core set for RA, including fatigue, stiffness, symptom persistence, systemic features, and participation. Patient self-report of flare was identified as a component of the research agenda needed to establish criterion validity for a flare definition; this can be used in prospective studies to further evaluate the Discrimination and Feasibility components of the OMERACT filter for a flare outcome measure.Conclusion.Our work to date has provided better understanding of key aspects of the RA disease process as episodic, potentially disabling disease worsening even when a patient is in low disease activity. It also highlights the importance of developing ways to enhance communication between patients and clinicians and improve the ability to achieve “tight control” of disease.
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Mahdi, Najat, Khadija Al-Ola, Abeer M. Al-Subaie, Muhallab E. Ali, Zaid Al-Irhayim, A. Qader Al-Irhayim, and Wassim Y. Almawi. "HLA Class II Haplotypes Distinctly Associated with Vaso-Occlusion in Children with Sickle Cell Disease." Clinical and Vaccine Immunology 15, no. 4 (February 13, 2008): 729–31. http://dx.doi.org/10.1128/cvi.00425-07.

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ABSTRACT We investigated the association of HLA class II alleles and haplotypes with sickle cell anemia vaso-occlusive crisis (VOC). DRB1*100101 was positively associated, while DRB1*140101, DRB1*150101, and DQB1*060101 were negatively associated, with VOC. Both susceptible (DRB1*100101-DQB1*050101) and protective (DRB1*110101-DQB1*030101 and DRB1*150101-DQB1*060101) haplotypes were identified, indicating that HLA class II haplotypes influence VOC risk.
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Dissertations / Theses on the topic "110701 Allergy"

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Schöndube, Andrea. "Illness, Media, and Culture." Doctoral thesis, Humboldt-Universität zu Berlin, Philosophische Fakultät II, 2011. http://dx.doi.org/10.18452/16327.

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Vergleichsweise wenige Texte in den Printmedien beschäftigen sich mit Allergie als Gegenstand öffentlichen Interesses. Deshalb untersucht die Dissertation die Darstellung von Allergien in Lifestyle-Magazinen im englisch- und amerikanischsprachigen Raum. Die vorliegende Arbeit befasst sich mit der Verbreitung von medizinischem Wissen durch die Medien. Sie zeigt, ob und wie die Medien zu Aufklärung und Information über Krankheiten, deren Relevanz, Diagnostik und Therapie, beitragen. Sie geht dabei besonders auf den Bedeutungsbereich von Wörtern ein, die als Metaphern benutzt werden. Das Fundament der Überlegungen bildet der Essay „Illness as Metaphor“ von Susan Sontag, in dem sie die Darstellung von Krankheiten und die Benutzung von Stereotypen abhandelt und Fragen, die im Zusammenhang mit Krankheit als sozialer und kultureller Angelegenheit stehen, aufwirft. Um den populärwissenschaftlichen Diskurs der analysierten Artikel in dieser Arbeit zu verstehen, wurde die von Jürgen Link entwickelte Diskursanalyse herangezogen, die sich eng an die Diskurstheorie Foucaults anlehnt. Die semiotischen Deutungsansätze werden mit Hilfe der Untersuchungen von Roland Barthes erklärt. Ziel der Arbeit ist es zu zeigen, wie die verschiedenen Diskurse ineinander greifen, welcher Mechanismus sich dahinter verbirgt und wo Ansatzpunkte für eine sachgerechte publizistische Behandlung des Themas liegen. Der Nutzen von Metaphern in der Beschreibung von Krankheiten liegt darin, dass sie kollektive Gefühlslagen ansprechen und den Denkraum des Möglichen erweitern. Dieser Aspekt ist besonders wichtig, da das Wort Allergie zu einer praktischen und populären Metapher für eine Reihe persönlicher, beruflicher oder politischer Antipathien geworden ist. Obwohl allergische Erkrankungen in der modernen Welt immer häufiger auftreten, räumen ihnen die Medien noch nicht den Platz ein, den sie -- auch ausgehend von der volkswirtschaftlichen Bedeutung der Erkrankungen -- dringend haben müssten.
Only a few print media focus on allergies as a matter of public interest. For this reason the dissertation analyzes the presentation of allergies in English and American lifestyle magazines. This thesis examines the propagation of medical knowledge via the media. It shows if and how the media contribute to health education and information about illness, its relevance, diagnostic investigation as well as therapy. The main focus is on those words which are used as metaphors. They represent an important subject of Susan Sontag''s essay „Illness as Metaphor“ which demonstrates the presentation of illness, the use of stereotypes and thus raises issues about illness being a social and cultural matter of interest. To understand the popular scientific discourse of this dissertation Jürgen Links'' discourse analysis is being used which follows closely Foucault''s theory. The semiotic interpretation is supported by the theories developped by Roland Barthes. This dissertation aims to show how the different discourses intertwine, to bring to fore the underlying mechanisms as well as an appropiate journalistic approach. The benefit of using metaphors when describing illness is that the collective state of mind is addressed and thus the range of thinking will be broadened. This aspect is especially important because the word allergy became a convenient and popular metaphor for a number of personal, professional or political aversions. Although allergies are dramatically on the raise in the modern world, their significance is not recognized yet by the media in their complexity as it should be the case, especially against the backdrop of the economic relevance of that illness
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Zurzolo, Giovanni. "The Role of Precautionary Labelling for Food Allergens and the Care of Children with Food Allergies." Thesis, 2014. https://vuir.vu.edu.au/25921/.

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There is no current cure for food allergy; therefore consumers with food allergy rely on accurate and detailed information on food labels in order to prevent an adverse reaction. Manufacturers cannot guarantee that food products are free from allergens as cross contamination can occur in several situations including but not limited to raw materials, the actual premises, storage and distribution, manufacturing processes and cleaning procedures. In order to alert the allergic consumer to the possible presence of trace allergens, manufacturers have voluntarily added precautionary labelling to processed foods. There are several variations to these statements, for example: “may contain traces of”, “may be present “and “made on the same production line”. The main purpose of this thesis is to understand the role of precautionary labelling in the care of children with food allergies.
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Conference papers on the topic "110701 Allergy"

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Dergachev, V. A., and I. V. Kudryavtsev. "RADIOCARBON EVIDENCE OF THE CLIMATIC CHANGES AND THE SOLAR ACTIVITY VARIATIONS DURING THE MEIENDORF – ALLEROD INTERSTADIAL EPOCH (~ 13000–11000 B.C.)." In All-Russia Conference on Solar and Solar-Terrestrial Physics. The Central Astronomical Observatory of the Russian Academy of Sciences at Pulkovo, 2018. http://dx.doi.org/10.31725/0552-5829-2018-145-148.

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