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1

Fiorillo, Matilde. "I segni nel PHerc. 1004 (Filodemo, Retorica, VII libro)." Doctoral thesis, Università degli studi di Trieste, 2013. http://hdl.handle.net/10077/8549.

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2011/2012
La tesi pubblica i risultati del censimento dei segni critici presenti nel papiro ercolanese 1004, contenente il settimo libro della Retorica di Filodemo di Gadara. L’introduzione è dedicata a una riflessione sull’importanza filologica e documentaria dei segni attestati nei papiri greco-egizi ed ercolanesi, a cui ha fatto da contraltare, per lungo tempo, la scarsa attenzione degli studiosi, il cui interesse primario era lo studio critico del testo tramandato. Il capitolo I offre una presentazione a tutto tondo del PHerc. 1004: del papiro viene offerta una descrizione tecnica (dimensioni del rotolo, tipologia libraria, paleografia) e contenutistica (struttura del libro e organizzazione del contenuto), a cui si accompagna una rassegna dei principali studi di cui il rotolo è stato oggetto negli oltre duecento anni trascorsi dalla data del suo svolgimento a oggi. Il capitolo II riassume i risultati del censimento dei segni in due serie di tabelle: la prima, denominata ‘tabella per colonna’, presenta i dati organizzati in ordine topografico progressivo, a partire dai frammenti fino all’ultima colonna del rotolo; la seconda serie di tabelle, invece, ordina i risultati ‘per segno’, in modo da offrire uno strumento di consultazione più rapido a chi sia interessato a una ricognizione dei segni presenti nel papiro in base alla loro tipologia. Il capitolo III espone in maniera discorsiva i risultati della ricerca: per ogni tipologia di segno riscontrata (paragraphos, spatium, paragraphos associata a spatium, diplé obelismene, stigmai, segni di correzione) vengono offerti una rapida descrizione e, successivamente, una casistica delle occorrenze più significative. Il testo delle colonne prese in esame per illustrare il valore dei segni è stato sempre controllato autopticamente, con l’ausilio delle immagini multispettrali; nel caso in cui l’autopsia abbia dato risultati diversi rispetto alle edizioni di riferimento, se ne è dato conto nell’apparato critico che accompagna alcune colonne. Le conclusioni, infine, riassumono in un’ottica complessiva i dati emersi dal censimento. La maggior parte dei segni è stata rilevata per la prima volta nel corso di questa ricerca: il miglioramento è stato possibile anche grazie all’impiego delle immagini multispettrali, che hanno permesso di evidenziare con maggiore chiarezza tracce di scrittura prima invisibili a causa della carbonizzazione subita dal rotolo e dello sbiadimento subito dall’inchiostro. I risultati emersi dallo studio consentono di identificare il PHerc. 1004 come un prodotto librario di buona qualità, destinato alla consultazione da parte di Filodemo stesso e dei suoi seguaci riuniti nel circolo epicureo di Ercolano.
XXV Ciclo
1985
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2

Kleinjohann, Keila Christina. "Texturização de aço baixo carbono SAE 1004 via plasma DC." Florianópolis, SC, 2011. http://repositorio.ufsc.br/xmlui/handle/123456789/95540.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência e Engenharia de Materiais
Made available in DSpace on 2012-10-26T03:11:19Z (GMT). No. of bitstreams: 1 294800.pdf: 18136348 bytes, checksum: 69f44778567e563dcb5b116652627ba7 (MD5)
Neste trabalho, amostras de aço baixo carbono SAE 1004 foram submetidas ao tratamento termoquímico de nitretação via plasma DC, visando obter uma texturização superficial e estruturação da microestrutura. Foram realizados estudos em diferentes condições para tratamento superficial de nitretação variando-se a mistura gasosa N2-H2 e empregando duas máscaras diferentes para promover a texturização superficial: grids de cobre e grids de níquel. Três concentrações de nitrogênio na mistura gasosa N2-H2 (baixa concentração, 5% de N2; concentração clássica de nitretação, 75% de N2; e alta concentração 95% de N2) foram empregadas. Com a escolha dessas variáveis no processo de nitretação foi possível definir a melhor condição de nitretação para a texturização. A caracterização superficial e microestrutural das camadas nitretadas foram realizadas por microscopia ótica (MO) e microscopia eletrônica de varredura (MEV). Medidas da rugosidade evidenciaram a formação de um padrão regular na superfície e testes de microdureza avaliaram o endurecimento das regiões obtidas. Os resultados mostram que é possível promover a texturização superficial utilizando a nitretação via plasma DC com o auxílio de máscara, a qual promove a formação da camada de compostos somente em regiões onde a superfície não está protegida. Esta texturização mostrou-se mais eficiente quando utilizados os grids de cobre e estes bem aderidos, nas regiões periféricas. Medidas de rugosidade mostraram que a estruturação da camada de compostos promove uma expansão perpendicular à superfície, viabilizando assim a texturização. Testes de microdureza superficial, juntamente com a análise microestrutural da camada nitretada corroboraram a estruturação. A camada de compostos apresentou uma descontinuidade, com regiões onde não ocorreu a formação, ou a camada de compostos apresentou-se muito fina
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3

Wilkins, Ruth. "Sociological aspects of the mother/community midwife relationship." Thesis, University of Surrey, 1993. http://epubs.surrey.ac.uk/1004/.

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4

Dhensa-Kahlon, Rashpal. "Healing or harmful? : a multi-method investigation of talk as a victim-centred response to organisational injustice." Thesis, London School of Economics and Political Science (University of London), 2014. http://etheses.lse.ac.uk/1004/.

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Organisational justice is dedicated to the study of perceptions of fairness within the workplace. Hundreds of studies converge on the notion that justice matters, such that profound negative implications arise when individuals perceive unfairness. Previous research has sought to manage and repair violations of fairness through three distinct means: managerial excuses and justifications, training interventions for managers, and remedies distributed by the organisation. There is an ironic shortcoming with this research: it ignores the victim who is at the centre of an injustice. Herein lies the starting point of the present thesis. Putting the victim back into the forefront of justice research, this thesis examines the role of a victim of workplace injustice in their own recovery process. It asks: can victims recover from the negative effects of a fairness violation, and more specifically, can talk, that is, conversation with others, aid such a recovery process? Recovery is defined as the emotional, cognitive and behavioural journey an individual goes through in order to work towards a resolution to their experience: it is a victim’s ongoing efforts to manage an injustice. Three empirical studies sought to examine if, when and how talk can assist victims with recovery, drawing on research within the justice literature as well as clinical and social psychology. Study 1, a mixed-methods design, provided support for the presence of talk in the context of workplace injustice, and led to the creation of a new measure of talk to reflect this. Study 2, a twice repeated cross-sectional survey, uncovered antecedents and consequences of talk; anger and thwarted justice needs were found to trigger talk, with an interaction between emotion and cognition talk driving victim-centred outcomes of rumination, self-affirmation and active solutions. Study 3, a ten-day daily diary investigation, found support for the notion that talk leads to positive recovery outcomes for victims of injustice. Contributions of this thesis, as well as implications and avenues for future research are discussed.
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5

Stube, John Carlson. "When 'farewell' is not 'goodbye' : a rhetorical reading of the farewell discourse, John 13-17." Thesis, Durham University, 2002. http://etheses.dur.ac.uk/1004/.

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The Farewell Discourse is a unique and climactic portion of John's Gospel which serves as a hinge on which the entire Gospel narrative pivots from Jesus' public ministry to his Passion. Shallow readings of this Discourse often pass over or ignore significant aspects of the text, especially the instruction and preparation Jesus was giving by word and action to make ready his disciples to continue his mission to the world after his departure. Other readings (notably form-critical) see the text as disarranged and therefore not a coherent whole. A thorough analysis employing the elements of Greco-Roman rhetoric has shown that there is a rhetorical dimension to the Discourse which makes sense of the text as a coherent whole. The Farewell Discourse was found to follow a rhetorical arrangement which gives a literary explanation to some assumed form-critical problems such as the ending at 14:31. Not only does this rhetorical structure give appropriate closure and transition with movement from one topic to another, it does so with a chiastic arrangement of the major topics. This thesis demonstrates that assumed disarrangements, repetitions and amplifications that have appeared problematic to other approaches do not detract from, but actually enhance the ability of the text to move and persuade. Rhetorical analysis is thus capable of giving insights into the text that otherwise might be overlooked or ignored. Throughout the Discourse, Jesus' ethos (character) as the divine one who "knows" stands out boldly and his persuasive appeal (logos) to the pathos (emotional response) of the disciples is strong, both as he seeks to move them beyond their present sorrow and distress and as he prepares them to face the future realistically and with confidence. The fourth evangelist thus presents Jesus operating rhetorically (in act as well as speech) and strategically uses Jesus' interaction with his disciples to seek a rhetorical outcome with his readers. This rhetorical approach provides a bridge between literary approaches on the one hand (which can proceed at the expense of taking into account the historical context) and historical critical approaches on the other (which can proceed at the expense of hearing the text speak as text). A rhetorical reading accounts for both literary and historical dimensions of the text. This thesis demonstrates that it is an effective interpretive methodology which elucidates dimensions of the text not adequately accounted for by other approaches.
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6

Gauvain, Richard. "An analysis of the Sunni Islamic concept of ritual pollution in light of previous research into pollution ideas." Thesis, Connect to e-thesis, 2002. http://theses.gla.ac.uk/1004/.

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Thesis (Ph.D.) -- University of Glasgow, 2002.
Includes bibliographical references (p. 281-296). Print version also available. Mode of access : World Wide Web. System requirements : Adobe Acrobat reader required to view PDF document.
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7

Stalteri, Michele. "La valutazione ambientale strategica del PRUSST di Forlì-Forlimpopoli: criteri per il monitoraggio." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amslaurea.unibo.it/1004/.

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8

Kaur, Harjinder. "Attitudes of South Asian men in the UK toward women and their understanding of, and justification for, domestic violence." Thesis, London Metropolitan University, 2015. http://repository.londonmet.ac.uk/1004/.

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To date nothing is known about the attitudes of South Asian men in the UK toward women and domestic violence. Issues related to South Asian men and communities have remained largely under the surface due to religious and cultural sensitivity. The aim of the research is to examine the attitudes of South Asian men in London and the South East of England toward women and their understanding and justification of domestic violence. More specifically, the research explores a range of cultural and religious actions and behaviours in relation to women and domestic violence that have specific reference and are pertinent to South Asian communities. This includes a focus on: educational and employment attainment; domestic labour/household duties; type of and freedom to choose clothes worn; living away from home; relationships before marriage; marriage; divorce; and domestic violence. The research applies an intersectional gender perspective as the key analytical concept to undertake the first dedicated multi-methodological study to explore South Asian men’s attitudes across a range of cultural and religious issues. It provides a baseline for understanding South Asian men’s perspectives, enabling policy and practice to tailor interventions to better assist South Asian women and engage in prevention. The first stage of the research consisted of piloting and constructing a new survey instrument; the South Asian Attitudes Toward Women and Domestic Violence Scale (SAATWDVS). South Asian men were approached in a range of locations to obtain diversity across socio-demographics such as age, ethnicity, religious affiliation, and country of birth or migration, and asked to complete the SAATWDVS survey instrument. The sample is 190 South Asian men. The second stage comprised nine in-depth face-to-face interviews with South Asian men to explore the issues in more depth. Concepts such as masculinity, tradition, culture, religion, and honour were explored. The findings show that whilst the majority of men held liberal attitudes, they were still setting the parameters of appropriate female behaviour. There appeared to be a difference, albeit small, between the public and private sphere. Where behaviour was deemed to be unacceptable this was often framed within concerns for the protection and well-being of women. Gender and gender relations are not static but evolving and becoming more progressive within the UK’s South Asian community. Men’s attitudes are understood as located in a complex interplay of factors: gender socialisation; religion; ethnic origin and country of birth; traditions; cultures; family/upbringing; the role of female family members; education; and interactions with female peers.
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9

Cedroni, Anna Rita <1969&gt. "Minori sordi stranieri: una realtà complessa e poco conosciuta." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2008. http://amsdottorato.unibo.it/1004/.

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10

Wollin, Sören [Verfasser]. "Störerhaftung im Immaterialgüter- und Persönlichkeitsrecht : Zustandshaftung analog § 1004 I BGB / Sören Wollin." Baden-Baden : Nomos Verlagsgesellschaft mbH & Co. KG, 2018. http://d-nb.info/116031103X/34.

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11

Amara, Allaoua. "Pouvoir, économie et société dans le Maghreb hammadide (395/1004-547/1152)." Paris 1, 2002. http://www.theses.fr/2002PA010589.

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Les Hammadides fondèrent un pouvoir central au Maghreb en 395/1004, marquant la fin de la période arabe dans cette région. Cette thèse se propose d'étudier la transformation des I structures politiques d'une organisation tribale berbère en une monarchie, à la lumière du schéma cyclique formulé par Ibn Khaldoun. Le maintien de structures tribales et l'intégration d'institutions étatiques orientales caractérisant l'organisation politique mise en place par la dynastie berbère des Hammadides. L'émergence de ce pouvoir central donna naissance à un nouveau espace politique nommé le Maghreb central. Ce nouveau pouvoir organisa une vie économique à dominante agricole. Il fonda deux métropoles commerciales, la Qal'a des Bani Hammâd et Bidjâya, qui connurent un essor important. Ses rendements agricoles importants permettaient au Maghreb hammadide de ravitailler les villes d'al-Andalus et de la Sicile en céréales. Néanmoins, plusieurs facteurs se sont accumulés pour faire régresser l'économie du Maghreb à la fin de l'époque hammadide : le réchauffement du climat, les déprédations hilaliennes ou de tribus berbères et les raids normands. Soutenu par le pouvoir, le malikisme étendit sa domination sur les principales régions du territoire hammadide, au détriment du shi'sme, du hanafisme et de l'ibadisme. Seule cette dernière doctrine résista et se structura, mais en perdant du terrain dans les régions septentrionales.
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12

Pérez, Arroyo Annalisa. "Caracterització molecular del gen GH1 en poblacions control i patològiques, patrons d'expressió en leucòcits de sang perifèrica i estudi funcional de proteïnes mutants detectades en pacients." Doctoral thesis, Universitat de Barcelona, 2007. http://hdl.handle.net/10803/1004.

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El retard de creixement pot ser secundari en un percentatge indeterminat de pacients a un problema genètic. En aquest treball s'analitza el gen de l'hormona de creixement (GH1) i s'estudien els canvis en la seqüència que produeixin un ARN missatger anòmal o una proteïna que no sigui funcional. S'ha estudiat el mapa polimòrfic del gen GH1 en una població control (n=307), per definir el mapa de SNPs. Alhora s'ha buscat un model en el qual poder estudiar l'expressió d'aquest gen. S'ha aïllat l'ARN de leucòcits de sang perifèrica tant de pacients com de controls, i s'ha amplificat el missatger de GH1. També s'ha posat a punt un model cel·lular en el qual poder estudiar la bioactivitat de les proteïnes recombinants portadores dels canvis detectats en pacients (Phe25Tyr i Val173Leu).

Les conclusions del treball han estat les següents:

1. Els nostres resultats han confirmat i ampliat la descripció de la variabilitat estructural del gen GH1. Han permès descriure el mapa complet per primera vegada, en una població adulta amb talla normal, compresa entre -2 i +2 SDS (n=307).

2. En les poblacions amb retard crònic de creixement (n=728) s'han detectat en un 11% de pacients canvis en la seqüència del gen GH1 diferents dels SNPs del mapa control. Entre els canvis, l'11,3% correspon a canvis puntuals d'un aminoàcid (1% del total de pacients índex).

3. L'expressió de GH1 en leucòcits de controls no és constitutiva ni constant en quant a les variants de splicing observades. Aquesta metodologia no permet detectar de forma fiable mutacions en pacients. En canvi, ens ha permès confirmar l'expressió de mutants com en el cas d'una substitució predictora de canvi d'aminoàcid, així com descartar o confirmar anomalies de splicing en al·lels portadors de canvis intrònics.

4. La utilització d'eines informàtiques ha permès realitzar una aproximació teòrica a l'efecte que dos canvis d'aminoàcid (Phe25Tyr i Val173Leu) a la proteïna GH tenen sobre la seva estructura i interacció amb GHR. L'anàlisi d'homologia de les proteïnes mutants amb les dels altres gens del clúster de la GH ha permès concloure que la substitució Phe25Tyr es pot haver generat per recombinació gènica amb el gen GH2, mentre que no és el cas per a la proteïna amb el canvi Val173Leu.

5. Les proteïnes recombinants obtingudes al laboratori (WT i mutants) han estat aptes per al seu estudi in vitro (inmunoreactivitat, proliferació cel·lular i bioactivitat).

6. Les GHs mutants Phe25Tyr i Val173Leu presenten una inmunoactivitat i una bioactivitat disminuïdes. Els models cel·lulars de les línies HepG2 i C-28/I 2 no han permès obtenir resultats, mentre que el model de cultiu primari de condròcits fetals humans ha permès detectar que les dues GHs mutants estimulen amb menor intensitat la transcripció de IGF1 mentre que provoquen un augment en l'expressió de GHR i IGF1R.

7. El canvi d'aminoàcid Phe25Tyr incorporat en un al·lel de GH1 portat en heterozigosi per dues famílies no relacionades es manifesta com a retard de creixement durant la infantesa que s'acompanya de resposta deficitària de secreció de GH i disminució de IGF1. La resposta al tractament amb GH és adequada i permet recomanar el tractament fins al final del creixement. El canvi Val173Leu detectat en una pacient amb talla baixa i RIUC, sense dèficit aparent de GH, permet suggerir que la detecció precoç de mutacions al gen GH1 quan la secreció aparenta ser normal, permetria un tractament més precoç que hagués millorat el seu pronòstic de talla final. L'anàlisi dels haplotips complets de GH1 permet interpretar l'efecte de la combinació de mutacions a la proteïna amb els genotips per als SNPs.


TITLE OF THE THESIS: "MOLECULAR CARACTERITZATION OF GH1 GENE IN CONTROL AND PATHOLOGIC POPULATIONS, EXPRESSION PATTERNS IN PERIPHERAL BLOOD LEUCOCYTES AND FUNCTIONAL STUDY OF MUTANT
PROTEINS DETECTED IN PATIENTS"

SUMMARY: The growth delay can be a secondary factor in front of a genetic problem in an indeterminate percentage of patients. In this work, it is analyzed the gene of growth hormone (GH1) and it is studied the changes in the sequence that produce an anomalous messenger ARN or a protein that is not functional. The polymorphic map of gene GH1 has been studied in a control population (n=307), to define the map of SNPs. At the same time, a model has been looked for, in which it could be possible to study the expression of this gene. The ARN of leucocytes of peripheral blood of patients and controls has been isolated, and the GH1 messenger has been amplified. Moreover, we have worked in a cellular model that allows us to study the bioactivity of recombinant proteins carrying the changes detected in patients (Phe25Tyr and Val173Leu).
The conclusions of the work have been the following ones:

1. Our results have confirmed and extended the description of the structural variability of gene GH1. They have allowed us to describe the complete map for the first time, in an adult population with normal stature, between -2 and +2 SDS (n=307).

2. In the populations with chronic growth delay (n=728) in an 11% of the patients, changes have been detected in the sequence of gene GH1 different from the SNPs of the map control. Within these changes, 11.3% correspond to precise changes in an amino acid (1% of the total of index patients).

3. The expression of GH1 in leukocytes of controls is neither constitutive nor constant as far as the observed variants of splicing. This methodology does not allow detecting without doubt the mutations in patients. However, it has allowed us to confirm the expression of mutants as in the case of a predicting substitution of change in amino acid, as well as discarding or confirming anomalies of splicing in carrying alleles of intronic changes.

4. The use of computer tools has allowed us to make a theoretical approach to the effect that two changes in amino acid (Phe25Tyr and Val173Leu) in protein GH have on their structure and interaction with GHR. The homology analysis of mutant proteins with those of the other genes of the cluster of the GH has allowed us to conclude that the Phe25Tyr substitution can have been generated by genic recombination with gene GH2, whereas it is not the case for the protein with the Val173Leu change.

5. The recombinant proteins obtained in the laboratory (WT and mutants) have been suitable for their study in vitro (inmunoreactivity, cellular proliferation and bioactivity).

6. The mutant GHs Phe25Tyr and Val173Leu show a diminished inmunoactivity and bioactivity. The cellular models of lines HepG2 and C-28/I2 have not allowed us to obtain results; in contrast, the model of primary culture of human foetal chondrocytes has allowed us to detect that the two mutant GHs stimulate with smaller intensity the IGF1 transcription and they cause an increase in the expression of GHR and IGF1R.

7. The change of Phe25Tyr amino acid incorporated in one allele of GH1 taken to heterozygosity by two non-related families is shown as growth delay during childhood accompanied by deficiency secretion answer of GH and diminution of IGF1. The response to the treatment with GH is suitable and allows us to recommend the treatment until the end of the growth. The Val173Leu change detected in a patient with short stature and RIUC, without apparent GH deficiency, allows us to suggest that precocious detection of mutations in gene GH1 when the secretion pretends to be normal, would allow a precocious treatment that would have improved its prognosis of final stature. The analysis of the complete haplotypes of GH1 allows us to interpret the effect of the combination of mutations in the protein with the genotypes for the SNPs.
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Earley, Robert. "DISCONNECT: Assessing and Managing the Social Effects of Development in the Athabasca Oil Sands." Thesis, University of Waterloo, 2003. http://hdl.handle.net/10012/1004.

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This research investigated the system by which the social effects of oil sands development on Fort McMurray, a city in northeastern Alberta, are assessed and managed. The research focused on Social Impact Assessment (SIA), Strategic Environmental Assessment (SEA), and the work of an industry initiative, the Regional Issues Working Group (RIWG). The oil sands industry, which involves large, labour-intensive mining and drilling operations in a boom-bust cycle, places considerable pressure on Fort McMurray, a city of approximately 50,000 inhabitants and the only urban area within 350 km of the oil sands. The social effects experienced there include exorbitant housing prices, shortages in service industry labour, insufficient social services, at times, to assist individuals and families who can no longer cope with the difficult conditions in the area, and a variety of other negative effects. Sixteen key informant interviews were conducted with urban planners, municipal politicians, provincial employees, a spokesperson for one of the First Nations in the area, community NGOs, and oil sands industry representatives. Data from the interviews were combined with a literature review and a document analysis. A modified McKinsey 7S Integrated Management Framework was used as a structure for describing and analyzing the Social Effects Assessment and Management System (SEAMS) in Fort McMurray. The SEAMS was found to be weak in comparison to the needs of the community. Project-by-project assessment of oil sands development was found to downplay the cumulative nature of social effects. Furthermore, no legislation or regulation existed that demanded action based on the findings of SIA. As a result, mitigation and management of social effects was insufficient, often occurring only when it was directly in the interests of the oil sands industry. While government and industry have plans in place to resolve some of the negative social effects, their actions were criticized by informants as being uncoordinated, inconsistent and often ineffective. The findings indicate that a strategy for exploiting Alberta's oil sands is necessary. The project-by-project evaluation of oil sands development proposals is not addressing the important long-term and regional social issues that arise as a result of construction and operation of the mines and facilities. A tool recommended for incorporating resolutions to long-term, regional social effects into the development plan is SEA with an explicit Strategic Social Assessment component. This strategic assessment and planning process should be undertaken by a publicly-accountable government body empowered to rationalize the pace of oil sands development based on social, environmental and economic effects, and to coordinate long-term responses by government and industry.
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Madzidzela, Liyanda. "An analysis of factors affecting housing delivery in the Nyandeni local municipality with specific reference to the Extension 4 Housing Project: a case study of Ward 21 in Ngqeleni." Thesis, Nelson Mandela Metropolitan University, 2008. http://hdl.handle.net/10948/1004.

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The study investigates problems and challenges that, the Nyandeni local municipality faces in terms of housing delivery to its communities. The purpose is to look at the factors that affect housing delivery at Nyandeni local municipality in the Extension 4 Housing Project in Ngqeleni and what can be done in order to improve it. The housing development at Nyandeni Local Municipality is not up to standard, the situation is worse in rural areas where there is not a single rural housing project that has been implemented thus far instead, there is a lack of infrastructure and other essential services. This is a serious problem that the Nyandeni local municipality faces, as a result the most vulnerable people are the poorest of the poor particularly those residing in rural areas. The study has investigated housing delivery at Nyandeni local municipality with reference to the Extension 4 Housing Project in Ngqeleni. The investigation indicates that there are serious challenges facing housing delivery. Hence the beneficiaries of the project could not get their houses in time and the project could not be completed within the scheduled period.
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15

Teh, Chor Tik. "Compliance and impact of corporate governance best practice code on the financial performance of New Zealand listed companies : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Business and Admnistration at Massey University, Auckland campus, New Zealand." Massey University, 2009. http://hdl.handle.net/10179/1004.

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The corporate governance best practice code (Code) of the New Zealand Exchange (NZX) came into effect on October 29, 2003. However, so far there is no systematic study of compliance with and impact of NZX Code on the performance of NZX companies. This study attempts to provide some answers to the perceived knowledge gap. The NZX Code recommends certain governance mechanisms to enhance corporate performance. The mechanisms analysed in this study are the percentage of independent directors, duality, presence of board subcommittees (audit, remuneration, and nomination), and the performance evaluation of board and individual directors. This thesis examines the possible relationship between recommended governance structures and the performance of NZX companies for the years 2003 (pre-Code) and 2007 (post Code), using data from the same 89 companies for each year. Although the number of companies adopting the NZX structures has increased, the rate of full compliance of the Code remains disappointingly low, rising from 5.6% in 2003 to just 22.5% in 2007. Probably due to the small sample size relative to the number of independent variables, and the problem of co-linearity, the multiple linear regression results do not seem to be conclusive and may be unreliable as the basis to form any formal statistical inference. However, treating the 89 companies as the whole population (89 out of 90), and using a simpler and more descriptive statistical tool to analyse the impact of individual independent variables on firm performance, the 2007 results show a consistent pattern of a positive relationship between Code compliance and firm performance, assuming all other factors being constant. This positive relationship is further reinforced by dividing the population into the various industry groupings as classified by the NZX, which also results in a consistent pattern of companies which comply fully with the Code structures financially outperforming companies that only partially comply with the Code during 2007. Surprisingly, listed companies adhering to the Chairman/CEO dual role do not seem to have impacted negatively on firm performance, contrary to agency theory expectation.
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Klein, Alexandra. "Telling our stories perceptions of parental conditional regard and their effects on narrative identity and well-being /." Diss., Connect to the thesis, 2007. http://hdl.handle.net/10066/1004.

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O'Heron, Rhyannon Leah. "Pregnant queer clinicians an exploratory study of the countertransference experiences of queer clinicians during their first pregnancies : a project based upon an independent investigation /." Click here for text online. Smith College School for Social Work website, 2007. http://hdl.handle.net/10090/1004.

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Thesis (M.S.W.)--Smith College School for Social Work, Northampton, Mass., 2007
Thesis submitted in partial fulfillment for the degree of Master of Social Work. Includes bibliographical references (leaves 74-75).
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Campos, Roberta Bivar Carneiro. "When sadness is beautiful : a study of the place of rationality and emotions within the social life of the Àve de Jesus." Thesis, University of St Andrews, 2000. http://hdl.handle.net/10023/1004.

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The ethnographic object of study of my thesis is a group of penitents, called ‘Ave de Jesus’, that dwells in the hinterlands of Northeast Brazil. As many other groups and penitents of this area they have a strong devotion to Padre Cicero -a deceased priest who founded the city in which they live, Juazeiro do Norte - who they believe to be Jesus himself. In fact, according to them, all the events of the Bible there in Juazeiro do Norte, such that they live in a biblical time, the Bible being their actual history which should culminate in destruction - A final end to the world. The Ave de Jesus have incorporated into their form of life the ways of being and relating to the world of those missionaries and religious leaders from the past, such as Padre Ibiapina, Antonio Conselheiro, Padre Cicero, and many ‘beatos’ who wandered throughout the ‘Sertao’* preaching penance and charity. Although these religious images make a lot of sense for those who live in such a harsh area as the ‘Sertoes’, there is no doubt that they are also in conflict with the mainstream system of interpretation of reality. In my thesis I explore how the biblical images take part in the construction and negotiation of truth and meaning, and how they work as references for acting, thinking and ‘feeling’. Because these biblical images are invariably related to moral sentiments - such as compassion, generosity, mercy, commiseration and a highly moral evaluation of the experience of suffering - that underlies the way of life of many penitents in Juazeiro, my thesis focuses on the social role of emotion in building up truth and creating sociability. The Chapter I provides the Introduction in which is given a bibliographical review on messianic and millenarian movements and pilgrimage, and points to my own theoretical choice. It is also in the introduction that I discuss the issue of rationality, ideology and narratives related to the problem of my research and the methodological approach. In Chapter III provide an overall ethnography of penance within the surrounds of Juazeiro do Norte in the past and present. In Chapter III I first introduce a brief ethnography of the Ave de Jesus. In Chapter IV I explore the situation of conflict between systems of interpretation within which Master Jose - the leader of the Ave de Jesus - finds himself. The subject of discussion in this chapter is the role of the affective and beauty in negotiating meaning and constructing truth. In Chapter VI dwell upon Emotions. In this chapter I provide a discussion concerning the importance of emotions in understanding the way of life of many penitents in Juazeiro do Norte, with special attention to the Ave de Jesus. Another subject of discussion is what an emotion is about and their relation to action and thought. In my ethnography and interpretation of emotions I have focused on those emotions which are cognitively stressed by the Ave de Jesus, such as suffering, compassion, mercy, etc. which underlies their form of life. In Chapter VI I provide a discussion on how images of charity are related to an ideal image of society -a Utopia. By going deeper into the relation between images of suffering, poverty and mendicancy I explore how the Ave de Jesus creates a sociality based on generosity, hospitality and sharing whereby they realise a messianic expectation. In the Conclusion I have tried to answer the main task of my thesis, that is, to provide an understanding of how sadness is beautiful. Through all the issues elected to for discussion in each chapter I intend to give support to my interpretation of the role and importance of emotions within the social life of the Ave de Jesus. *The semi-arid backlands of Northeast Brazil
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Gabe-Thomas, Elizabeth. "Individual differences in warning perception : the role of risk-taking propensity." Thesis, University of Plymouth, 2012. http://hdl.handle.net/10026.1/1004.

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Warnings are intended to improve safety (decreasing injury, illness and loss) by communicating the presence and nature of a potential hazard and encouraging behaviour that will minimise or avoid a negative outcome. Warnings can be seen as representations of risk, therefore it is likely that an individual’s attitude towards risk, their risk-taking propensity, may affect the way they perceive warnings. Establishing this relationship has important practical implications. If high risk-taking propensity can predict non-compliance, then attempts may be made to increase compliance within high risk-takers by tailoring warnings to such individuals. This thesis aims to explore empirically the relationship between measures of risk-taking propensity and warnings, with potential application to the prevention of hazardous behaviours. Study One investigated the potential relationship between risk-taking propensity and warning perception using an exploratory approach. The results confirmed that various measures of risk-taking propensity predicted warning perceptions, in particular on intentions to comply with the warnings. Studies Two and Three revealed that the relationship between risk-taking and warning perception is domain specific to a certain extent and that it is stronger when contextual information about a hazard is provided. Study Four explored potential underlying mechanisms and revealed that while the mental simulation of positive outcomes of non-compliance was found to be influential, anticipated regret significantly mediated the relationship between risk-taking propensity and intended compliance. Study Five attempted to minimise the discrepancy between high and low risk-takers through warning design manipulation. Despite a strong effect of sensation seeking on intended compliance the warning manipulations implemented had no effect on warning perceptions. This thesis offers a significant contribution to the literature, by establishing empirically the effect of risk propensity on warnings perception and by providing insight into the theoretical underpinnings of this relationship.
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Dil, Jonathan. "Murakami Haruki and the search for self-therapy." Thesis, University of Canterbury. Languages and Cultures, 2008. http://hdl.handle.net/10092/1004.

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This thesis offers a reading of the first eleven novels of popular Japanese novelist Murakami Haruki, as well as a selected number of his short-stories and non-fictional works, as an evolving therapeutic discourse. In short, it is a response to Murakami's own claim to have started writing fiction as a means of self-therapy. Murakami, I will argue, is primarily responding to existential anxieties that have been magnified by conditions of cultural decline in late-capitalist Japan. His resulting therapeutic discourse shares interesting parallels with certain psychoanalytic theories of the twentieth century. Previous psychoanalytic readings of Murakami's work have tended to take either the writings of Carl Jung or Jacques Lacan as their starting point. This thesis will argue, however, that both theoretical frameworks are needed if one is to truly understand where Murakami is coming from. This kind of therapeutic reading might seem to justify those critics who see only the escapist elements in Murakami's fiction and who fault him for failing to engage fully with the important political and social issues of his day. In fact, a therapeutic reading, I will argue, is the best way to see how closely related Murakami's search for self-therapy and his growing search for commitment really are.
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Whelchel, Larma Ford. "The implications of aging, health status, and survival strategies among older Black women in one large and one small urban population in Georgia." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 1997. http://digitalcommons.auctr.edu/dissertations/1004.

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The literature on minority aging in the United States reveals a lack of adequate research data on minorities, especially on older black women. Members of different ethnic or minority groups are subjected to different socioeconomic problems throughout life and especially as they grow older. This study focuses on research collected during a 1996 study of the aging, health status and survival strategies of black females between the ages of 65 to 95, in a large versus small urban population. This study also employed quantitative survey questionnaire methodologies, to test the hypotheses that aging, health status and survival strategies impact the longevity of these women. Based on the analysis of the review of pertinent research literature and standard reference texts, a survey questionnaire was developed and tested. The survey instrument was administered to a prescreened, random sample of women in West Atlanta and East Macon, Georgia. One hundred and twenty surveys were administered (100%) were returned.
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Letsie, Maserame Maria. "Recent developments in Tswana literature : a narratological study of short stories of B.D. Magoleng and S.A. Moroke / Maserame Maria Letsie." Thesis, Potchefstroom University for Christian Higher Education, 2002. http://hdl.handle.net/10394/1004.

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In this thesis some trends in Setswana literature of the past 50 years are described and analysed. Through the analyses of selected short stories by Moroke and Magoleng, thematic and stylistic aspects are discussed. The central problem, the aims and objectives are outlined and motivated in the first chapter. In chapter two, the historical background of Setswana as a language, the structure of traditional oral literature in Setswana as well as modern written Setswana literature are examined. Chapter three outlines a number of theoretical concepts from contemporary narratology. For example, analyses of the following short stories, such as, "O potile noga ka fa mosimeng", "Ga a le ka la tewa" and "Khutsana" are done using the basic narratological theoretical framework as it is described and used by Du Plooy (1986 & 1991), Bal (1981 & 1985), Rimmon-Kenan (1983) and Genette (1980). A narratological analysis is based on the text level of the stories. Chapters four and five explore the detailed narratological analyses of the four stories by Moroke, namely, "Mhalatsl', "Ramonamane le baesekele", "Mma, boammaarure bo tla mpoloka" and "Ntwa magareng ga makau le makgarebe" and Magoleng's four stories namely; "Mokaragana, ngwanaka", "Ga le a ka la tswa", "Ke mosadi", and "Dikeledi". In these stories, temporal relations such as sequence, rhythm, frequency, characterization, space, focalization and various aspects of narration are analysed. This is mostly done in accordance with Du Plooy's narratological model (1986:342- 372). The characteristics of Moroke and Magoleng's short stories such as structure, style and theme are presented. Long before the development of a written language, people had been telling stories. The oral heritage continues to nourish the written literatures, especially as regards world-view, subject matter, theme, structure, style and devices for character delineation. For instance, Moroke uses the behavioural attitudes of his characters to enhance the didactic elements. In his work, nothing from outside is used for the titles. The abundant use of Biblical references clearly reflects his feelings, while Magoleng treats various themes such as tradition and culture, love and marriage, urban life and social problems. His style highlights the magnitude of certain issues to express his worldviews. As to the present, oral art now coexists with written literature and has opened new fields of scholarly interest, one of which is the oral-written interface. The forerunners of creative literature in Setswana are undoubtedly the translations done by the missionaries and those by a Motswana, Sol T. Plaatje. In chapter six, cultural identity is explored. An exposition of Hofstede's theory is given and then the focus is shifted to cultural issues in the stories by Moroke and Magoleng. It is clear that the cultural background determines the stories and knowledge of the cultural content, beliefs and traditions of Batswana people. It is necessary to understand the stories and some examples by Moroke and Magoleng are discussed. In Setswana literature naming is a crucial stage in man's capacity for symbol formation. Traditionally, names take on special significance beyond the expression of identity. In Batswana communities, names that are given to children symbolize their cultural identities. Witchcraft is associated with darkness or evil. One of the dominant features of Batswana society is respect for gifts. It is not only the uncles who give gifts; the relatives and families also give gifts, even if these may be materially smaller than those of the uncles. It is concluded that Moroke and Magoleng's short stories portray significant developments in Setswana literature, and fully warrant analysis and investigation.
Thesis (Ph.D. (African Languages))--Potchefstroom University for Christian Higher Education, 2003.
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Ho, Valerie. "An Analysis Of Water Rates And Home Prices: A Case Study." Scholarship @ Claremont, 2015. http://scholarship.claremont.edu/cmc_theses/1004.

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The issue of the rising Claremont water rates has been a heated topic of debate over the last couple of years. This study is part of a larger body of literature that seeks to determine the extent to which a location-specific amenity or dis-amenity is capitalized into housing values, and specifically aims to examine the relationship between water rates and home prices in Claremont. To do this, it uses houses in La Verne, where water rates have not been rising as rapidly, as a control group. Specifically, the regression model looks at whether the differences in the water bills between Claremont and La Verne are associated with the differences in the house prices between Claremont and La Verne. In doing so, it also provides an estimate of the price discount faced by houses in Claremont due to the water rate.
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Boulton, Sallyanne. "Biological effects of novel poly (adenosine diphosphate ribose) polymerase inhibitors." Thesis, University of Newcastle Upon Tyne, 1995. http://hdl.handle.net/10443/1004.

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Poly(ADP-ribose) polymerase (PADPRP) is a nuclear enzyme with a well documented role in DNA repair. Inhibitors of PADPRP, (e.g. 3' substituted benzamides) potentiate the cytotoxicity of a wide range of antitumour drugs. The results presented in this thesis represent, to the best of my knowledge, the first comprehensive and quantitative assessment of the ability of a range of P ADPRP inhibitors to modulate the cellular responses to damaging agents. Two novel PADPRP inhibitors, 8-hydroxy-2-methyl quinazolin-4(3H)-one (NU1025) and 3,4 dihydro-5-methoxyisoquinolin-1-(2H)-one (PD 128763) were compared with two "classical" PADPRP inhibitors, 3-aminobenzamide (3AB) and benzamide (BZ). The relative potencies for 3AB, BZ, NU1025 and PD 128763 as PADPRP inhibitors in vitro were 1.0, ~1.0, ~43 and ~53 respectively. All compounds potentiated the growth inhibition and cytotoxicity of the monofunctional alkylating agent temozolomide (TM) in L1210 cells. For example, 10/-lM NUI025 and PD 128763 gave dose enhancement factors (DEF) of ~2 at 100/0 survival, whereas ImM 3AB and 0.5mM BZ where required to give similar DEF values. Cellular NADl- levels were depleted up to 50% by 1-2mM TM and this depletion was completely prevented by coincubation with 50-100µM PD 128763 and 1-3mM 3AB. TM induced DNA single strand break levels were increased in a concentration dependent manner by the P ADPRP inhibitors. Overall, the relative potencies for ability of the compounds to potentiate TM induced growth inhibition, cytotoxicity and DNA single strand breaks showed good correlation with those determined in an in vitro inhibition study, with both NU1025 and PD 128763 exhibiting ~60 fold increased inhibitory activity as compared to 3AB. The PADPRP inhibitors per se did not effect the growth or survival of the L 121 0 cells, nor increase DNA strand breakage. NAD+ is the substrate for PADPRP. A L1210 cell line made resistant to tiazofurin (TZ) utilising a step wise selection protocol was shown to be deficient in nicotinamide mononucleotide adenyl transferase (NMNAT) , the final enzyme required for NAD+ biosynthesis. The consequences of a reduced NMNAT activity (<3% of the parental line ) and an ~40% reduction in intracellular NAD+ levels were determined. The resistant cells showed an ~3 fold increased sensitivity to TM as compared to the parental cells. Upon coincubation with increasing concentrations of NU1025 in the presence of a fixed concentration of TM, growth inhibition was potentiated ~70 fold in the resistant cells but only ~10 fold in the parental cell line, demonstrating the reduced level of competition between NAD+ and NUI025 for PADPRP. However, DNA single strand breaks were increased in the resistant compared to the parental cell line only when NU1025 was coincubated with TM. In contrast, in the presence of the PADPRP inhibitors alone, equivalent growth inhibitory effects were observed in each of the cell lines, suggesting inhibition of PADPRP was not the cytotoxic effector. The ~40% NAD+ depletion observed could therefore suggest, that NAD+ levels in the resistant cells were reduced to, or near to the KmNAD+ for PADPRP.
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Harrison, M. "Synthesis of acyclic c-nucleosides as potential antiviral agents." Thesis, Heriot-Watt University, 1988. http://hdl.handle.net/10399/1004.

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Aquilina, Ronald. "IT strategizing of small firms in Malta : a grounded theory approach." Thesis, Robert Gordon University, 2014. http://hdl.handle.net/10059/1004.

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The contribution of small firms towards the creation of economic value in a country’s Gross Domestic Product, employment and innovation is widely acknowledged. Relatively little is known on how small firms are adopting IT strategically to acheive business-IT alignment and how alignment changes over time. This study examines from a dynamic perspective IT adoption actions undertaken by owner-managers, in relation to business-IT alignment in small firms in the island state of Malta. To attain its research objectives, the methodological stance adopted in this research study is that of grounded theory. Moving away from a deductive approach, this study embraces a constructivist approach using a combination of inductive and abductive thought. No fewer than thirty-one in-depth interviews are conducted with owner-managers to observe alignment patterns of IT adoption behaviour in their respective small firms operating in Malta and employing up to 49 employees. Four business-IT alignment equilibrium states are identified, serving as markers to map out the common IT alignment paths that each firm pursued, not necessarily in linear form, during their operational years. A substantive model, which identifies four distinct IT alignment patterns, denotes each common path that a group of firms took in their movement from one alignment equilibrium state to another, throughout their life-cycle stages. This study has substantive application and comprises several implications for the development of IT adoption behaviour when small firms endeavour to strategically align business with IT. It provides policy-makers, academic researchers and small firms’ owner-managers with a theoretical framework that can provide them with factors that can predict the kind of alignment patterns that are likely to occur. Findings indicate that the quality of IT related technological solutions that are taken up by each small firm are reliant on the owner-manager’s characteristics that focus mainly on the knowledge of internal IT expertise and the project management capabilities to manage IT outsourcers. Given that few studies have been conducted to study and establish patterns of IT alignment in small firms, this research provides an important contribution to knowledge and to the existing academic literature.
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Buss, Whitney. "The Dark End of Day." ScholarWorks@UNO, 2009. http://scholarworks.uno.edu/td/1004.

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Vieira, Carla Francisca de Sousa. "Elaboração e caracterização de iogurte de extrato hidrossolúvel da amêndoa de baru (Dipterix Alata Vog.)." Universidade Federal do Tocantins, 2017. http://hdl.handle.net/11612/1004.

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A inclusão de alimentos regionais na dieta contribui para a promoção de hábitos alimentares saudáveis e para o desenvolvimento da economia da região. O objetivo deste trabalho foi desenvolver uma bebida fermentada tipo iogurte a partir de extrato hidrossolúvel de amêndoas de baru e leite integral. Foram desenvolvidas nove formulações diferentes, variando a concentração de extrato e açúcar, visando obter os parâmetros ideais de cada um dos substratos na formulação da bebida fermentada. As melhores formulações, selecionadas por Análise Sensorial Descritiva Quantitativa, foram as elaboradas com maior quantidade de açúcar. A quantidade de extrato hidrossolúvel de baru adicionada não afetou as características sensoriais nem a qualidade global das formulações. As três melhores formulações de iogurte, F5 (elaborada com 50% de EHB e 6% de açúcar), F6 (elaborada com 50% de EHB e 12% de açúcar) e F9 (elaborada com 75% de EHB e 12% de açúcar) foram caracterizadas físicoquímicamente e permaneceram armazenadas sob refrigeração durante quatro semanas, com verificação dos parâmetros microbiológicos (coliformes totais e termotolerantes, Salmonella e bolores e leveduras), pH, cor objetiva e teor de sólidos solúveis (°Brix) nos tempos de armazenamento 0, 7, 14, 21 e 28 dias. Também foram realizados testes afetivos de aceitação e de intenção de compra, com provadores não treinados. Não foram identificados microrganismos do grupo coliformes nem Salmonellas durante o período de armazenamento. Houve acidificação e alteração na cor e teor de sólidos a cada semana. Os resultados obtidos nos testes de aceitação e de intenção de compra demonstraram que a formulação F6, elaborada com 50% de extrato hidrossolúvel de amêndoas de baru e 12% de açúcar, foi a que alcançou melhores resultados, apresentando índice de aceitação de 83,5% no parâmetro impressão global e tempo de vida útil de 21 dias.
The inclusion of regional foods in diet contributes to the promotion of healthy and the development of the regional economy. The objective of this study was to develop a drink type yogurt from water-soluble extract of the baru almond and milk. Nine different formulations were developed, varying the concentration of extract and sugar, in order to obtain the ideal parameter of each of the substrates in the fermented beverage formulation. The best formulations, selected by Quantitative Descriptive Sensorial Analysis, were those elaborated with the highest amount of sugar. The amount of water-soluble extract of de baru almond did not affect the sensory characteristics of the formulations. The three best yoghurt formulation, F5 (elaborated with 50% EHB and 6% sugar), F6 (elaborated with 50% EHB and 12% sugar) and F9 (elaborated with 75% HBs and 12% sugar) were characterized physico-chemically and were stored under refrigeration for four weeks with checking the microbiological parameters (thermotolerant and total coliforms, Salmonella and molds and yeasts), pH, objective color and soluble solids content (° Brix). There were also acceptance and purchase intention tests with untrained tasters. No microorganisms from the coliform group or Salmonellas were identified during the storage period. There was acidification and change in color and solids content at storage. The results obtained in the acceptance and purchase intention tests showed that the formulation F6, elaborated with 50% water-soluble extract of baru almond and 12% sugar, was the one that obtained better results, with acceptance of 83.5 % for the global impression parameter and shelf life of 21 days.
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Rodrigues, Vera de Brito. "Satisfação com o suporte social em indivíduos com perturbação psiquiátrica: estudo exploratório." Bachelor's thesis, [s.n.], 2008. http://hdl.handle.net/10284/1004.

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Monografia apresentada à Universidade Fernando Pessoa, como parte integrante dos requisitos para obtenção do grau de licenciada em Psicologia, especialização em Psicologia Clínica
O suporte social é hoje considerado como uma variável capaz de proteger e promover a saúde (Siqueira, 2008). Sendo um dos principais objectos de estudo da Psicologia da Saúde (Paixão & Oliveira, 1996), torna-se cada vez mais pertinente o seu estudo, em especial com a população de doentes psiquiátricos, visto que em Portugal existe uma carência de respostas adequadas para as pessoas com doença psiquiátrica grave (Guterres & Frasquilho, 2004). Neste estudo exploratório de carácter observacional foram aplicados um questionário sócio-demográfico e a Escala de Satisfação com o Suporte Social (Ribeiro, 1999a) a 80 indivíduos com perturbação psiquiátrica, sendo 23 (28,8%) do sexo masculino e 57 (71,3%) do sexo feminino, com idades compreendidas entre os 19 e 73 anos (M = 44,14; D.P. = 11,724). Esta amostra foi recolhida no Serviço de Santo Tirso do Hospital de Magalhães Lemos entre os dias 15 de Abril e 24 de Julho de 2008. A análise dos dados comporta uma vertente quantitativa, cujo objectivo é avaliar a percepção de satisfação com o suporte social destes indivíduos, de acordo com as suas características sócio-demográficas. Os resultados obtidos evidenciam que se verificam diferenças estatisticamente significativas relativamente à satisfação com o suporte social entre as pessoas que praticam e as que não praticam religião (p ≤ 0,05) tanto para a Escala geral como para os factores “satisfação com os amigos” e “satisfação com a família”. Tendo em consideração que a satisfação que cada um de nós tem com o seu suporte social é fundamental para a manutenção da saúde física e mental; então, a intervenção nesta área torna-se extremamente relevante. The social support is today considered as a variable capable of protecting and promoting health (Siqueira, 2008). Being one of the principal objects of study of the Health Psychology (Paixão & Oliveira, 1996), his study becomes more and more relevant, in special with the population of psychiatric patients, since there is a lack of answers adapted for the persons in Portugal with psychiatric serious disease (Guterres & Frasquilho, 2004). In this exploratory study of observacional character they were applied a questionnaire demographic-partner and the Scale of Satisfaction with the Social Support (Ribeiro, 1999a) to 80 individuals with psychiatric perturbation, being a 23 (28,8 %) of the masculine sex and 57 (71,3 %) of the feminine sex, with ages understood between 19 and 73 years (M = 44,14; D.P. = 11,724). This sample was gathered in the Serviço de Santo Tirso do Hospital de Magalhães Lemos between the days 15 of April and 24 of July of 2008. The analysis of the data holds a quantitative slope, which objective is to avaluate the perception of satisfaction with the social support of these individuals, in accordance with his characteristics demographic-partner. The obtained results show up what happen statistically significant differences relatively to the satisfaction with the social support between the persons whom they practice and who do not practice religion (p ≤ 0,05) both for the general Scale and for the factors “ satisfaction with friends ” and “ satisfaction with family ”. Having in consideration that the satisfaction what each one of us has with his social support is basic for the maintenance of the physical and mental health; then, the intervention in this area becames extremely relevant.
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Pires, Ana Luísa de Oliveira. "Educação e formação ao longo da vida." Doctoral thesis, Faculdade de Ciências e Tecnologia: Universidade Nova de Lisboa, 2002. http://hdl.handle.net/10362/1004.

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Tese de Doutoramento em Ciências da Educação
Este trabalho de investigação, desenvolvido no domínio da Educação/Formação de Adultos, centra-se no estudo dos Sistemas e Dispositivos de Reconhecimento e Validação de Aprendizagens e de Competências adquiridas pelos adultos em contextos não-formais e informais, ao longo das suas trajectórias pessoais, sociais e profissionais. O objectivo é contribuir para o aprofundamento da compreensão de uma problemática inovadora – o reconhecimento e a validação –, principalmente na perspectiva da Educação e Formação ao Longo da Vida. Considerando que esta problemática se situa na interface entre o sistema educativo, o mundo do trabalho e a sociedade em geral, o quadro teórico de referência foi construído a partir de uma abordagem multidisciplinar, de forma a fornecer um quadro compreensivo que pudesse abarcar a complexidade dos fenómenos em questão, na perspectiva da investigação educativa. O estudo empírico foi desenvolvido através de uma análise comparativa realizada a nível internacional, com a finalidade de identificar e caracterizar os sistemas e dispositivos – já implementados ou em vias de implementação – num conjunto significativo de países.
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Jorge, Salomé Mariana Candeias. "Traumatismos medulares em canídeos." Bachelor's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2009. http://hdl.handle.net/10400.5/1004.

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Dissertação de Mestrado Integrado em Medicina Veterinária
Os traumatismos medulares representam uma parte importante da casuística de um hospital veterinário. As causas destes traumatismos podem ser intrínsecas e extrínsecas. A principal causa intrínseca é a extrusão do material do disco intervertebral (Hérnia discal tipo I de Hansen). As principais causas extrínsecas são fracturas, luxações e subluxações vertebrais secundárias a eventos traumáticos. As lesões de origem vascular (tromboembolismo de uma artéria medular terminal ou embolismo fibrocartilaginoso) são incluídas nos traumatismos medulares porque a patofisiologia destas lesões é semelhante à das lesões de origem mecânica. A fisiopatologia dos traumatismos medulares caracteriza-se pela existência de uma lesão primária mecânica (compressão e/ou concussão) que desencadeia uma avalanche de lesões secundárias mediadas pela existência de radicais livres de oxigénio, alteração das concentrações de neurotransmissores, iões e ácidos aminados excitatórios e pela alterações de outros factores bioquímicos, culminando em redução do fluxo sanguíneo medular, isquémia e necrose. O diagnóstico diferencial das causas de traumatismo medular deve ser feito com base nas informações recolhidas na história pregressa, no exame físico e no exame neurológico. Os principais meios auxiliares de diagnóstico utilizados são o exame radiográfico da coluna vertebral, com recurso a mielografia na maioria dos casos, e a análise do líquido cefaloraquidiano. Ocasionalmente são utilizadas técnicas de imagem avançadas como TAC e RM. O diagnóstico de embolia fibrocartilaginosa pode ser feito por RM e a confirmação com exame histopatológico post mortem da medula espinhal lesada. O tratamento inicial dos traumatismos medulares envolvia em regra a administração de doses elevadas de corticosteróides nas primeiras horas após o trauma, no entanto, actualmente, este conceito está a cair em desuso devido à falta de ensaios clínicos que demonstrem com clareza os efeitos desta terapêutica. As fracturas, luxações e subluxações vertebrais, e as hérnias discais de tipo I podem ter uma terapêutica médica ou cirúrgica dependendo das características de cada caso. Nas embolias fibrocartilaginosas o tratamento é sempre médico. A fisioterapia é uma parte importante da terapêutica dos casos de traumatismo medular. O estudo de novas terapêuticas para as lesões medulares é uma área em constante expansão que tem o potencial de beneficiar pacientes humanos através da realização de ensaios clínicos em canídeos.
ABSTRACT - Spinal trauma represents an important part of a veterinary hospital’s case load. Its causes can be of internal or external sources. The main internal source of acute spinal injury is acute intervertebral disk disease (herniation of the nucleus pulposus), also know as Hansen’s type I disk disease. The main external sources of acute spinal injury are vertebral fractures, luxations and subluxations secondary to traumatic events. Vascular spinal injuries (terminal spinal cord artery thromboembolism or fibrocartilaginous embolism) are also referred to when discussing spinal trauma because of the similar pathophysiology. Spinal trauma pathophysiology includes the primary mechanical injury (compression and/or concussion) which unleashes a chain of secondary lesions, mediated by excessive oxygen free radicals, alteration in neurotransmitters, electrolytes and excitotoxic amino acids concentrations and by changes in various other biochemical factors that collectively result in reduced spinal cord blood flow, ischemia and necrosis. The differential diagnosis for spinal trauma is made based on the information obtained from the owner, from the physical examination and from the neurologic examination. The main ancillary methods used for the diagnosis of spinal trauma are the radiographic examination, myelography in most cases, and cerebrospinal fluid analysis. Advanced imaging techniques like CT and MRI can be used occasionally. The diagnosis of fibrocartilaginous embolism is made by MRI and confirmed by post-mortem histopathologic examination of the damaged spinal cord. The initial treatment for acute spinal injury was usually performed by administrating high doses of corticosteroids during the first hours after the onset of the injury, however, this idea is currently being refuted due to lack of clinical studies that clearly demonstrate this treatment’s effectiveness. Vertebral fractures, luxations and subluxations, and Hansen’s type I disk disease may have a medical or surgical treatment. The treatment for fibrocartilaginous embolism is medical. Physical therapy represents a very important role in the recovery of acute spinal cord injury patients. The development of new therapies for acute spinal cord injury in dogs may benefit human patients with the same pathology.
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32

Toletti, Glória Maria Marques Afonso Esteves. "Representações dos estudantes finalistas sobre as práticas profissionais de enfermagem: Contributos para a educação e o aprender em enfermagem." Master's thesis, Instituto Superior de Psicologia Aplicada, 2004. http://hdl.handle.net/10400.12/1004.

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Dissertação de Mestrado em Psicologia Educacional
Na educação em enfermagem, enquanto disciplina aplicada, a prática desempenha um papel de enorme relevância, na medida em que constitui por excelência o lugar para onde convergem todas as aprendizagens. A preocupação central deste estudo foi "situarmo-nos" melhor face à situação educativa. Duas questões conduziram esta investigação: - O que sabem os estudantes finalistas sobre as práticas profissionais de enfermagem? - Como foram (re)construindo esses saberes, através das práticas pedagógicas socialmente organizadas pela educação em enfermagem? Pela sua natureza enquanto modalidade de conhecimento prático que une sujeito-objecto, a teoria das representações sociais constituiu-se como um mediador para aproximarmos a realidade dos participantes do nosso estudo apelando directamente às suas vivências e experiência, tentando compreender e explicar a situação actual do objecto de investigação. Por outro lado, a ambiguidade da noção de "prática" implicou uma profunda pesquisa documental, no sentido da sua desconstrução, propondo-se uma definição sustentada do campo da prática profissional de enfermagem. Estudar problemas educativos sem delimitar os complexos contextos em que ocorre a acção educativa, corre o risco de se tornar infrutífero, dada a frequente impossibilidade de generalização dos resultados. O presente estudo foi delimitado a uma única Escola Superior de Enfermagem e os participantes constituídos pelos estudantes finalistas que voluntariamente se disponibilizaram para nele participar, constituindo por dezanove elementos. Trata-se de um estudo exploratório que associou vários métodos e instrumentos, visando proporcionar um olhar alargado da realidade empírica e nesse sentido deve ser entendido apenas como ponto de partida para estudos futuros que visem aprofundar aquilo que parecem constituir algumas tendências que se poderão constituir futuramente como pistas de análise e investigação em psicologia educacional. A representação social dos estudantes sobre as práticas profissionais de enfermagem, foi estudada a partir de dois critérios de prática: a prática "como modos de fazer" e a "prática como cálculo'1, suportando-nos exclusivamente em medidas de "saliência" que permitem enunciar algumas propostas quanto aos elementos susceptíveis de integrar o núcleo da representação social neste grupo de estudantes. Os resultados obtidos parecem apontar para uma organização dos elementos da representação em torno de uma concepção de "cuidar" enquanto meta-organizadora e condutora da prática, constituindo a intenção global que a prática de cuidados materializa. Neste sentido, a estrutura da representação social, sugere a centralidade das "práticas profissionais" por oposição às "práticas tradicionais", revelando que è a função específica do enfermeiro no campo da saúde das populações, que sustenta a prática, enquanto acção humana finalizada e intencional. Como foram (re)construindo esses saberes, através das práticas pedagógicas socialmente organizadas pela educação em enfermagem, começamos por verificar que em função da preferência vocacionai, que conduziu os participantes a optar pelo curso/profissão de enfermagem - primeira opção, opção possível - o campo representacional que possuíam da profissão antes de ingressarem no curso, aproximado por narrativas escritas, revelou diferenças significativas. A ideia de uma profissão de ajuda e do humano ocupava a quase totalidade do campo representacional daqueles para quem esta constituiu a sua primeira opção. Nesta linha também se verificaram algumas diferenças face ao auto-conceito de competência. Na dimensão social de competência não havia diferenças entre os grupos, mas nas dimensões cognitiva e de criatividade os estudantes para quem enfermagem constituiu a opção possível apresentavam valores tendencialmente mais elevados. Interrogamo-nos se estas tendências não tecem relações com o imaginário simbólico da profissão, frequentemente identificado com a mulher veiculando uma imagem do "eterno feminino". Os ensinos clínicos -experienciais - parecem ocupar um lugar de centralidade na reconstrução e reinterpretação destes saberes sobre as práticas, confirmando o resultado de estudos anteriores. Mas os estudantes referem claramente as práticas pedagógicas que favorecem este processo de apropriação - estimular a reflectir, questionar, investigar, dar autonomia e responsabilidade - sustentadas porém, por um conjunto de práticas relacionais e de suporte, que lhes permitam lançar-se em novas experiências. Também são valorizadas todo um conjunto de "atitudes éticas e existenciais", um existir na sua individualidade, que nos faz pensar numa aproximação a uma imagem de uma "enfermeira real", com vida própria e participando activamente, tanto no mundo profissional como civil.
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Paulo, Luísa Alexandra Serrano. "Determinação dos teores de resveratrol em vinhos tintos com denominação de origem controlada Beira Interior e avaliação das suas propriedades antimicrobianas." Doctoral thesis, Universidade da Beira Interior, 2011. http://hdl.handle.net/10400.6/1004.

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Reconhece-se actualmente que o vinho tem propriedades benéficas no organismo humano, sendo constituído por compostos que exercem uma influência positiva no metabolismo dos indivíduos que o consomem com regularidade e moderação. O resveratrol (trans-3,4’,5-trihidroxiestilbeno) é uma fitoalexina que está presente em diversos alimentos e bebidas, em particular no vinho tinto. Das várias classes de polifenóis existentes no vinho, o resveratrol (estilbeno) é um dos compostos mais estudados do ponto de vista de importância biológica, devido aos potenciais efeitos benéficos para a saúde humana. Na primeira parte deste trabalho foi desenvolvido e validado um método analítico sensível, com vista a determinar, quantitativamente, as concentrações de resveratrol em amostras de vinhos tintos portugueses, utilizando a extracção em fase sólida (SPE) e a cromatografia líquida de alta eficiência acoplada a um detector de díodos (HPLC-DAD). Na segunda parte, foram implementadas técnicas, tais como, o método de difusão em disco e o método da microdiluição, que permitiram avaliar a actividade antimicrobiana do resveratrol em diversos microrganismos, nomeadamente bactérias Gram-positivas (Bacillus cereus, Staphylococcus aureus e Enterococcus faecalis) e Gram-negativas (Escherichia coli, Klebsiella pnemoniae, Salmonella typhimurium e Pseudomonas aeruginosa). O efeito do resveratrol em bactérias Gram-positivas foi também analisado, recorrendo-se às curvas de morte, de forma a tentar assim compreender se o resveratrol actua como um agente bactericida ou bacteriostático. Analisou-se, ainda, a acção do resveratrol em Bacillus cereus, recorrendo à microscopia e à citometria de fluxo, de forma a tentar compreender o mecanismo de acção deste composto. Finalmente, foi também avaliada a actividade antimicrobiana do resveratrol em diferentes estirpes de Helicobacter pylori, utilizando o método da difusão em disco e o método da diluição em agar. Para além disso, verificou-se a hipótese do resveratrol e amostras de vinho tinto (devidamente quantificadas na primeira parte deste trabalho) inibirem a actividade da urease de H. pylori, considerada um dos principais factores de virulência deste microrganismo. Complementou-se, ainda, o estudo analisando cineticamente a actividade da urease na presença do resveratrol. O método analítico foi validado de acordo com normas internacionalmente aceites quanto a: especificidade, linearidade, limites de detecção (LOD) e de quantificação (LOQ), precisão, exactidão, estabilidade e eficiência de extracção. Verificou-se ainda a aplicabilidade do método, analisando 186 amostras de vinhos tintos comerciais, provenientes de diferentes regiões, castas e anos. Os resultados obtidos demonstraram que os níveis de trans-resveratrol nos vinhos tintos, variaram entre 0,05 e 10,9 μg/mL, enquanto que as concentração de cis-resveratrol variaram entre 0,04 e 8,71 μg/mL. No que diz respeito à actividade antimicrobiana do resveratrol, verificou-se que este composto possui actividade contra todas as bactérias Gram-positivas em estudo. Os resultados demonstraram que o resveratrol tem um efeito bacteriostático que afecta o crescimento da célula bacteriana em todas as estirpes testadas. Quanto ao mecanismo de acção do resveratrol, os resultados obtidos sugerem que o crescimento celular do Bacillus cereus foi inibido, o que por sua vez terá levado à paragem da divisão celular. Na última parte deste trabalho, confirmou-se a actividade antibacteriana do resveratrol em diferentes estirpes de Helicobacter pylori. Para além disso, quer o resveratrol, quer os vinhos tintos analisados demonstraram um efeito inibitório na actividade da urease de Helicobacter pylori. A análise cinética revelou que o resveratrol é um inibidor da urease não competitivo e reversível. O presente trabalho contribuiu por um lado, para o melhor conhecimento do teor de resveratrol nos vinhos portugueses, e por outro demonstrou o potencial do resveratrol como agente antibacteriano, podendo no futuro ter potenciais aplicações tanto na conservação dos alimentos como na terapia clínica.
It is now recognized that wine has beneficial properties for the human health, since it is constituted by compounds that exert a positive influence on the individuals’ metabolism, provided that the consumption is moderate. The phytoalexin resveratrol (3,4’,5-trihydroxistilbene) is commonly found in foodstuffs and drinks, particularly in red wine. From the various classes of polyphenols presented in wine, resveratrol (stilbene) is one of the most studied from the viewpoint of biological importance, due to the possible beneficial effects on the human health. In the first part of this work it was developed and validated a sensitive analytical method for the quantitative analysis of resveratrol in portuguese red wines, using solid phase extraction (SPE) and liquid chromatography coupled with diode array detector (HPLC-DAD). In the second part the antimicrobial activity of the compound was evaluated by means of different techniques, such as the disc diffusion and microdilution methods, and the studied microorganisms included Gram-positive (Bacillus cereus, Staphylococcus aureus and Enterococcus faecalis) and Gram-negative (Escherichia coli, Klebsiella pneumoniae, Salmonella typhimurium and Pseudomonas aeruginosa) bacteria. We also analyzed the effect of resveratrol on Gram-positive organisms using time-kill assays, in order to understand whether resveratrol acts as a bactericide or bacteriostatic. In order to understand the mechanism of action of this compound, its action against Bacillus cereus was analysed by microscopy and flow cytometry. Finally, the antimicrobial activity of resveratrol against different strains of Helicobacter pylori was evaluated using both the disk diffusion and agar dilution methods. In addition, we verified the ability of resveratrol and red wine samples (properly quantified in the first part of this work) to inhibit the urease activity of H. pylori, since this is considered a major virulence factor of this microorganism. Moreover, we complemented the study analyzing kinetically urease activity in the presence of resveratrol. The analytical method was fully validated according to internationally accepted guidelines, regarding specificity, linearity, limits of detection (LOD) and quantification (LOQ), precision, accuracy, stability and extraction efficiency. Once validated, the methodology was applied to 186 commercial red wine samples from different regions, grape varieties and vintage. The results showed that the content of trans-resveratrol in red wines ranged from 0.05 to 10.9 µg/mL, while the concentration of cis-resveratrol ranged from 0.04 to 8.71 µg/mL. Regarding the antimicrobial activity of resveratrol, we found that this compound has activity against all tested Gram-positive bacteria. The results demonstrated that resveratrol has a bacteriostatic effect which affects bacterial cell growth in all tested strains. As regards the mechanism of action of resveratrol, the results suggest that cell growth of Bacillus cereus was inhibited, which may in turn stop cell division. In the last part of this work, we confirmed the antibacterial activity of resveratrol against different strains of Helicobacter pylori. Furthermore, both resveratrol and red wines showed an inhibitory effect on urease activity of Helicobacter pylori. The kinetic analysis revealed that resveratrol is a non-competitive and reversible inhibitor of urease. The present work contributed to the best knowledge of portuguese wines regarding the levels of resveratrol, and demonstrated the possible use of this compound as an antibacterial agent, and may in future have potential applications for both food preservation and clinical therapy.
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Carvalho, Paulo Alexandre Matos de. "Índice multicritério da perceção de qualidade do ambiente interior." Doctoral thesis, Universidade de Coimbra. Faculdade de Ciências e Tecnologia. Departamento de Engenharia Mecânica, 2014. http://hdl.handle.net/10400.8/1004.

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Tese de Doutoramento em Engenharia Mecânica, na especialidade de Aerodinâmica, apresentada à Faculdade de Ciências e Tecnologia da Universidade de Coimbra para obtenção do grau de Doutor
Neste trabalho são analisadas as contribuições do ambiente térmico, do ambiente acústico, do ambiente visual e da qualidade do ar para a perceção global da qualidade ambiental de um espaço interior. Os resultados obtidos repercutem a perceção humana após um tempo de exposição prolongada ao mesmo ambiente. Todos os ensaios efetuados, ao longo de cerca de dois anos, decorreram em contexto de sala de aula, no Campus de uma instituição de ensino superior e em edifícios naturalmente ventilados. Verificou-se que, nas condições referidas, é possível prever a perceção global de qualidade do ambiente interior com base em apenas três das quatro variáveis mencionadas: Conforto Térmico, Conforto Visual e Conforto Acústico. Para cada uma destas variáveis é possível determinar os respetivos voto médio previsível e percentagem previsível de insatisfeitos em função de um conjunto de variáveis físicas objetivamente mensuráveis. No caso do ambiente térmico verificou-se que o voto médio previsível, calculado de acordo com as correspondentes normas internacionais, apresenta boa concordância com o conjunto de resultados obtidos. No caso da percentagem previsível de insatisfeitos com o ambiente térmico, é proposta uma nova metodologia para a obtenção deste índice que apresenta vantagens ao nível da interpretação física dos resultados obtidos. Ainda no âmbito do conforto térmico, foi efetuada uma análise detalhada da aplicação do standard de conforto térmico adaptativo. Verificou-se que num contexto em que o nível de atividade metabólica é constante para toda a população, são as mesmas variáveis que influenciam o nível de isolamento térmico do vestuário que também influenciam a temperatura interior de conforto e exatamente nas mesmas ponderações. Com base nas conclusões obtidas, é proposta uma nova metodologia para o cálculo da temperatura interior de conforto adaptativo. É ainda proposto um novo índice de temperaturas: A Razão de Equivalência Térmica, concebido para a regulação de temperatura em edifícios naturalmente ventilados e edifícios híbridos. Nos casos dos conforto acústico e conforto visual, foram desenvolvidos dois índices do Voto Médio Previsível e Percentagem Previsível de Insatisfeitos, respetivamente para cada um destes. Em ambos os casos, o Voto Médio Previsível é obtido com base em grandezas físicas medidas localmente. No caso da perceção de qualidade do ar interior e nestas condições de exposição longa duração, não foi possível identificar um conjunto de grandezas físicas que permitam estimar o Voto Médio Previsível respetivo. É possível no entanto estimar a Percentagem Previsível de insatisfeitos com a qualidade do ar apenas com base no voto médio observado para esta perceção. A formulação matemática correspondente é apresentada, conjuntamente com as demais. Ainda no âmbito da perceção de qualidade do ar, foram identificados alguns efeitos que se supõem estar associados à matriz de distribuição espacial humana e que provocam alterações nas ponderações com que as perceções de ar viciado e de odores influenciam o voto médio de qualidade do ar. Em ensaios realizados em condições de exames finais, verificou-se que os "estados de alma" (traduzidos pela autoavaliação da performance face às expectativas iniciais) não influenciam as avaliações individuais de perceção da qualidade de cada um dos ambiente considerados nem tão pouco a avaliação global efetuada ao ambiente interior no seu todo. Verificou-se que todas as quatro perceções do ambiente interior, bem como a perceção global do mesmo, possuem uma matriz comum da curva de percentagem previsível de insatisfeitos em função do voto médio respetivo, quando este é expresso em escala unipolar.
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Morales, Tello Ingrid Ebeling. "Respuestas de adaptación a la enfermedad en pacientes con cáncer de mama, según el modelo de Callista Roy : Hospital Loayza, 2011." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2011. https://hdl.handle.net/20.500.12672/1004.

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Los objetivos fueron determinar las respuestas de adaptación a la enfermedad en pacientes con cáncer de mama, según el Modelo de Callista Roy .El estudio de investigación es de tipo cuantitativo, de nivel aplicativo el método es descriptivo explicativo, la muestra se selecciono mediante el muestreo no probabilístico, por conveniencia , el cual estuvo constituido por 40 pacientes con cáncer de mama que tenían un tiempo de diagnostico mínimo de 1 meses y que se encontraban o no realizando algún tipo de tratamiento . La información fue recolectada a través de un cuestionario que consto de 33 preguntas. Los datos fueron procesados por paloteo manual, presentando los resultados en tablas estadísticos para su análisis e interpretación. Se concluye que con respecto al Modo Fisiológico que las pacientes tienen dificultad para conciliar el sueño y mala calidad del mismo a la vez que mostraron inconformidad con el cambio de alimentación, respecto al Modo de Auto concepto las mujeres con pocas expectativa de vida futura frente a la vida y enfermedad; en el Modo de Función de rol, se encuentran con una actividad social muy limitada ; en el Modo Interdependencia se evidencia mejoría en las relaciones que tienen con su pareja quienes son su principal apoyo. --PALABRAS CLAVES: RESPUESTAS ADAPTATIVAS, MODOS ADAPTATIVOS
The objectives were to determine the adaptive responses to the disease in patients with breast cancer, according to the model of Roy. The research study is quantitative, application-level explanation is descriptive method, the sample was selected by sampling nonprobability, for convenience, which consisted of 40 patients with breast cancer diagnosis had a minimum time of 1 months and who were or not doing some kind of treatment. The information was collected through a questionnaire containing 33 questions. The data were processed by manual paloteo, presenting results in the statistical tables for analysis and interpretation. We conclude on Mode Physiological that patients have difficulty sleeping and poor quality of the show while dissatisfaction with the dietary change, selfconcept regarding the mode found women with few expectations about life and disease in the role function mode, there is a very limited social activity and the interdependence mode is evident improvement in the relationships they have with their partners who are their main support. KEYWORDS: ADAPTIVE RESPONSES . ADAPTIVE MODES.
Tesis
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Miller, Noleen Bonita. "The impact of the workplace environment on the emotional and physical wellbeing of call centre agents in the Cape Metropole." Thesis, Cape Peninsula University of Technology, 2014. http://hdl.handle.net/20.500.11838/1004.

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Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Business Administration in the Faculty of Business at the Cape Peninsula University of Technology 2014
Call centres have become an important source for organisations to provide efficient information to their customers through cost-effective communication channels. Call centres are defined as a work environment in which the main business is mediated by computer- and telephone-based technologies that allow the effective distribution of incoming calls to available staff, and permit customer–employee communication simultaneously with the use of display screen equipment (DSE) and instant access to information. Working in a call centre is often linked with high stress levels, difficult customers, shift work, high workload demand, absenteeism and high employee turnover rates. The work characteristics of call centres include performance targets where employees are required to achieve set targets, undergo close performance monitoring, performance appraisal systems, limited task variation, repetitive work and limited autonomy. The physical environment in the call centre is often associated with open-plan office layouts and booths where noise levels and workstations are positioned in close proximity to each other. Wellbeing in call centres has become a concern and the research was undertaken to establish what effects the working environment (physical environment and job characteristics) in call centres in the Cape Metropole has on the wellbeing of call centre agents. A quantitative research method was employed in the study. A structured questionnaire was distributed via SurveyMonkey® to call centre agents from four participating call centres in the Cape Metropole. The combined target population of the four call centres was 760. A sample size of 200 was determined by using the Raosoft Incorporated® calculation tool. Although the aforesaid sample size sufficed, a response rate of 275 was received. Questions relating to job characteristics and significance of the work were based on the Job Diagnostic Survey by Hackman and Oldham. Social support questions were based on the instrument developed by Caplan, Cobb, French, Van Harrison & Pinneau in 1975. Job demand questions were based on the instrument developed by Karasek in 1979, and only the section on job demand was used. Performance monitoring and physical work environment were measured by using the questions based on these variables by Sprigg et al in 2003. Emotional wellbeing questions relating to burnout were measured using the Oldenburg Burnout Inventory. The wellbeing questions relating to vocal health, optical health and auditory health were based on the questionnaires developed by Sprigg et al. in 2003. General health was measured using the “Somatic Complaints” section of the NIOSH Generic Job Stress Questionnaire. Musculoskeletal health problems were measured using the Cornell Musculoskeletal Discomfort Questionnaire (CMDQ) developed by Hedge in 1994. Research question 1 addressed the gender perceptions of job characteristics, physical work environment and emotional and physical wellbeing. A T-test was conducted to answer the research question and the results revealed that there was no significant difference in gender perception on job characteristics; however there was a significant difference in perception of the physical work environment and wellbeing. Research question 2 addressed whether there is a significant difference in emotional and physical wellbeing experienced by call centre agents from various industries. A MANOVA analysis was conducted to determine the significance in industries, p = .015, and an ANOVA analysis was conducted that revealed agents working in the online retail as well as financial service industries were more likely to experience disengagement, p = .035. Research question 3 addressed the factors in the workplace environment that contribute to emotional and physical wellbeing problems. An ANOVA analysis was conducted and the results revealed lack of skills variety, p = .014, contributes to exhaustion; lack of autonomy, p = .040, contributes to disengagement; lack of supervisor support, p = .009, contributes to exhaustion, job demands, p = .000, contribute to exhaustion, performance monitoring, p = .036, contributes to exhaustion; and workstation layout, p = .001, contributes to auditory health problems. Research question 4 addressed whether there is a significant relationship between job characteristics, physical work environment and wellbeing. A Pearson correlation analysis was conducted and the results revealed that there is a significant relationship between job characteristics, physical work environment, and wellbeing. It can be concluded that the workplace environment does have an impact on the wellbeing of call centre agents in the Cape Metropole. It is imperative that the management of call centres understand the nature of the job and how the physical environment contributes to job stress; burnout; vocal, auditory, and optical health problems; and musculoskeletal disorders. The researcher recognises that there are essential job characteristics associated with call centre work but that there are elements of the job that can be redesigned to improve the wellbeing of call centre agents. It is recommended that management implement interventions which will redesign those elements within the workplace environment that contribute to wellbeing issues. The findings of this study add to existing literature and knowledge of the workplace environment and wellbeing of call centre agents.
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Pumpichet, Sitthapon. "Novel Online Data Cleaning Protocols for Data Streams in Trajectory, Wireless Sensor Networks." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/1004.

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The promise of Wireless Sensor Networks (WSNs) is the autonomous collaboration of a collection of sensors to accomplish some specific goals which a single sensor cannot offer. Basically, sensor networking serves a range of applications by providing the raw data as fundamentals for further analyses and actions. The imprecision of the collected data could tremendously mislead the decision-making process of sensor-based applications, resulting in an ineffectiveness or failure of the application objectives. Due to inherent WSN characteristics normally spoiling the raw sensor readings, many research efforts attempt to improve the accuracy of the corrupted or “dirty” sensor data. The dirty data need to be cleaned or corrected. However, the developed data cleaning solutions restrict themselves to the scope of static WSNs where deployed sensors would rarely move during the operation. Nowadays, many emerging applications relying on WSNs need the sensor mobility to enhance the application efficiency and usage flexibility. The location of deployed sensors needs to be dynamic. Also, each sensor would independently function and contribute its resources. Sensors equipped with vehicles for monitoring the traffic condition could be depicted as one of the prospective examples. The sensor mobility causes a transient in network topology and correlation among sensor streams. Based on static relationships among sensors, the existing methods for cleaning sensor data in static WSNs are invalid in such mobile scenarios. Therefore, a solution of data cleaning that considers the sensor movements is actively needed. This dissertation aims to improve the quality of sensor data by considering the consequences of various trajectory relationships of autonomous mobile sensors in the system. First of all, we address the dynamic network topology due to sensor mobility. The concept of virtual sensor is presented and used for spatio-temporal selection of neighboring sensors to help in cleaning sensor data streams. This method is one of the first methods to clean data in mobile sensor environments. We also study the mobility pattern of moving sensors relative to boundaries of sub-areas of interest. We developed a belief-based analysis to determine the reliable sets of neighboring sensors to improve the cleaning performance, especially when node density is relatively low. Finally, we design a novel sketch-based technique to clean data from internal sensors where spatio-temporal relationships among sensors cannot lead to the data correlations among sensor streams.
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Hauer, Erik Sebastián. "Una medida de inflación subyacente exclusion-based para el Perú." Master's thesis, Universidad del Pacífico, 2015. http://hdl.handle.net/11354/1004.

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Hay poco consenso en la literatura sobre el diseño y evaluación de medidas de inflación subyacente. Estudios previos han mostrado que las medidas más técnicas de influencia limitada tienen mejor rendimiento empírico. Sin embargo, es deseado que las medidas de inflación subyacente sean lo más transparentes y replicables posibles, lo cual usualmente resulta en medidas más simples “exclusion-based”. A este respecto, se utiliza una nueva metodología de extracción de señal a la inflación para encontrar medidas de inflación subyacente “exclusion-based” para el Perú, usando cuatro especificaciones diferentes. Los errores estándares de las medidas encontradas con respecto a los benchmarks son todos menores que los errores estándares de las medidas de inflación subyacente del Banco Central de Reserva del Perú (BCRP) (medida estándar y medida que excluye alimentos y energía -A&E-) con respecto a los mismos benchmarks. Luego, se utilizan tres criterios estadísticos para probar la conveniencia de estas medidas más formalmente. Aquí se encuentra que, para la muestra corta, la medida estándar del BCRP y la medida encontrada utilizando un promedio móvil centrado (PMC) de 36 meses cumplen con los criterios, y que por lo tanto pueden considerarse medidas válidas de inflación subyacente. Finalmente, se simula un shock ortogonal a estas dos medidas de inflación subyacente utilizando un modelo autorregresivo vectorial para evaluar cuán rápido la inflación converge a su valor de equilibrio. La medida de inflación subyacente encontrada utilizando el benchmark PMC (36) permite una convergencia más rápida en la inflación que la medida estándar del BCRP. Para futuros estudios, se recomienda encontrar un óptimo global empleando técnicas de simulación.
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Leite, Maria da Glória Oliveira Gomes Neto. "O presidente do conselho executivo e as representações dos professores." Master's thesis, Universidade de Aveiro, 2007. http://hdl.handle.net/10773/1004.

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Mestrado em Análise Social e Administração da Educação - Administração da Educação
Pretende-se com este trabalho conhecer com alguma profundidade quais as representações que o corpo docente tem do Presidente do Conselho Executivo, enquanto líder do órgão de gestão das escolas. Elegemos dois modelos privilegiados de interpretação da escola com organização social-a escola como burocracia e a escola como cultura. Partimos destas lentes para descrever os pressupostos teóricos que sobrevoamos, não descurando o contexto histórico, normativo e legal da administração escolar das escolas públicas no decorrer do século XX. Cruzamos diferentes visões sobre as representações sociais, particularmente aquelas que se interligam com os professores e a escola. Procuramos dar relevo às questões da liderança sob diferentes teorias, dos papéis, funções e perfis dos gestores escolares, particularmente no contexto de charneira de politicas educativas que hoje vivemos. Do ponto de vista da metodologia utilizada, preconizamos uma investigação qualitativa num estudo de caso, que procurou pôr em evidência as representações dos professores sobre o seu Presidente, num Agrupamento de Escolas desde o pré-escolar até ao terceiro ciclo. O estudo empírico levou-nos a concluir que os professores têm uma representação dominante do Presidente do Conselho Executivo como um professor, recusando os gestores profissionais, evidenciando ainda a importância dos contextos para o surgimento das representações dos docentes. ABSTRACT: By this work we aim to understand, as deeply as possible, the way teachers, in a school, represent the President of the Executive council as the leader of the school administration. We have elected two privilege models to interpret school as a social organization: school as bureaucracy and school as culture. We have departed from these lenses to describe the theoretical presuppositions which we have flown over, without neglecting the historical, normative and legal context of public schools administration in the XX century. We have intersected different sights about the social representations, particularly those which are related to teachers and school. We have tried to emphasize the questions concerning leadership under different theories, the roles, the tasks and profiles of the school director, particularly in the changing context of educational politics we have been facing. As far as methodology is concerned, we have proclaimed a quantitative investigation based on the teachers’ representations towards their President, in Agrupamento de Escolas, from pre school to 9th grade. The empirical study led us to realize that teachers represent the President of the Executive Council as a teacher and they refuse the professional manager. It also demonstrates the importance of the context to formulate the teachers’ representation.
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Wyant, Tiana L. "Influence of Anti-CD44 on Murine B Cell Activation." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd/1004.

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Lymphocyte activation and trafficking are indispensable to the immune system. CD44, an adhesion molecule, plays important roles in T cell activation, lymphocyte homing/trafficking, and tumor metastasis. Although the functions of CD44 have been shown in T cells and other leukocytes, little is known about its role in B cells. The effects of CD44 cross-linking on murine B cell activation via CD40L/IL-4 was explored using the anti-CD44 mAbs RK3G9 and IM7. Immobilized RK3G9 and IM7 could strongly inhibit B cell proliferation and Ig production, with IgE inhibition being prominent. Soluble anti-CD44 had no effect. The inhibitory effect of RK3G9 was not influenced by addition of anti-FCγRII, indicating no role for the inhibitory receptor. The effects of delayed addition of immobilized anti-CD44 mAbs were studied, and the results indicated no inhibition after 96 hrs of culture. B cells were also activated by either LPS or anti-IgM F(ab')2. While LPS-induced B cell activation was inhibited by immobilized anti-CD44 mAbs, anti-IgM activation was refractory. Interestingly, addition of both anti-IgM and CD40L or LPS resulted in some modulation of the inhibitory activity. Additionally, FACS and Elispot revealed that RK3G9-treated cells had reduced numbers of plasma cells. Taken together, these results suggest that CD44 cross-linking could control polyclonal B cell activation by CD40L, but allow sIgM/CD40L activation to continue.
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Villatoro, Cecilia. "An Application and Analysis of Recursive Sudvidision Schemes." Scholarship @ Claremont, 2017. http://scholarship.claremont.edu/scripps_theses/1004.

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The following paper discusses the application of two subdivision algorithms for the purpose of finding an optimal way of rendering smooth spherical surfaces. Subdivision algorithms are used on three dimensional models. These algorithms typically manipulate the original object to produce one that is more visually pleasing and more realistic to the object we are attempting to recreate. We applied two popular subdivision algorithms to some simple meshes to compare their outcomes. In this project we implemented some of these algorithms in order to gain some insight into how these algorithms differ in the way that they are transforming the input mesh. Our desired goal was to see if there is any basis for which we can say that one algorithm outperforms the other. Our comparison runs through several iterations of subdivision and compares their theses meshes visually. In comparing these meshes our desired visual outcome is a mesh that is more smooth or more spherical. Another metric we looked at was the number of faces being produced for each mesh. In addition, we compared the algorithms in terms of the time they took to perform subdivision. These metrics form the basis for our comparison of performance and we discuss the details of these further in this paper.In our results we found that the two algorithms we are comparing perform quite similarly on certain meshes with respect to the visual output and the time they take to perform subdivision. On meshes of different types however the algorithms might output visually distinguishable meshes upon repeated subdivisions. Finding what factors influence whether the algorithms perform similarly provides an avenue for future work.
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42

McNeil, Patrick. "Integrating Multiple Modalities into Deep Learning Network." NSUWorks, 2017. http://nsuworks.nova.edu/gscis_etd/1004.

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Deep learning networks in the literature traditionally only used a single input modality (or data stream). Integrating multiple modalities into deep learning networks with the goal of correlating extracted features was a major issue. Traditional methods involved treating each modality separately and then writing custom code to combine the extracted features. Current solutions for small numbers of modalities (three or less) showed there are multiple architectures for modality integration. With an increase in the number of modalities, the “curse of dimensionality” affects the performance of the system. The research showed current methods for larger scale integrations required separate, custom created modules with another integration layer outside the deep learning network. These current solutions do not scale well nor provide good generalized performance. This research report studied architectures using multiple modalities and the creation of a scalable and efficient architecture.
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43

Pan, Jianjia. "Image segmentation based on the statistical and contour information." HKBU Institutional Repository, 2008. http://repository.hkbu.edu.hk/etd_ra/1004.

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44

Drolia, Utsav. "Adaptive Distributed Caching for Scalable Machine Learning Services." Research Showcase @ CMU, 2017. http://repository.cmu.edu/dissertations/1004.

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Applications for Internet-enabled devices use machine learning to process captured data to make intelligent decisions or provide information to users. Typically, the computation to process the data is executed in cloud-based backends. The devices are used for sensing data, offloading it to the cloud, receiving responses and acting upon them. However, this approach leads to high end-to-end latency due to communication over the Internet. This dissertation proposes reducing this response time by minimizing offloading, and pushing computation close to the source of the data, i.e. to edge servers and devices themselves. To adapt to the resource constrained environment at the edge, it presents an approach that leverages spatiotemporal locality to push subparts of the model to the edge. This approach is embodied in a distributed caching framework, Cachier. Cachier is built upon a novel caching model for recognition, and is distributed across edge servers and devices. The analytical caching model for recognition provides a formulation for expected latency for recognition requests in Cachier. The formulation incorporates the effects of compute time and accuracy. It also incorporates network conditions, thus providing a method to compute expected response times under various conditions. This is utilized as a cost function by Cachier, at edge servers and devices. By analyzing requests at the edge server, Cachier caches relevant parts of the trained model at edge servers, which is used to respond to requests, minimizing the number of requests that go to the cloud. Then, Cachier uses context-aware prediction to prefetch parts of the trained model onto devices. The requests can then be processed on the devices, thus minimizing the number of offloaded requests. Finally, Cachier enables cooperation between nearby devices to allow exchanging prefetched data, reducing the dependence on remote servers even further. The efficacy of Cachier is evaluated by using it with an art recognition application. The application is driven using real world traces gathered at museums. By conducting a large-scale study with different control variables, we show that Cachier can lower latency, increase scalability and decrease infrastructure resource usage, while maintaining high accuracy.
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45

Kadel, Rajesh. "Surface structure study of imidazolium based ionic liquid." Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/1004.

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46

Manning-Ouellette, Amber Lynn. "A WOMAN'S VOICE: A QUALITATIVE STUDY ON HOW FIRST-YEAR COLLEGE WOMEN UNDERSTAND THEIR SEXUAL EXPERIENCES." OpenSIUC, 2015. https://opensiuc.lib.siu.edu/dissertations/1004.

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A significant social and personal area of the first-year of college is the freedom to engage in casual sex relationships. There is an indication that negative emotions and regret effect women longer than men (Esbaugh & Gute, 2008; Lambert, Kahn, & Apple, 2003; Littleton, Tabernik, Canales, Backstrom, 2009; Morgan & Zurbriggen, 2009; Nack, 2008). The purpose of the study is to investigate how first-year college women understand their sexual experiences. By gathering narratives directly from first-year college women regarding their sex education background and experiences, this dissertation will obtain information needed to offer the types of successful strategies and information secondary and postsecondary education can provide women to strengthen their cognitions and to enlighten their college experiences. This qualitative study investigates how women understand their sexual experiences through women's cognitive development. I conducted twelve 90-minute interviews with a diverse set of first-year college female participants using a structured interviewing technique with open-ended questions. This structure provided an opportunity for exploration of student's sexual decision-making and understanding of the experiences. My interviewing techniques mimic the strategies of grounded theory and I interpreted my data through a three phase thematic coding process guided by the theoretical framework of Belenky, Clinchy, Goldberger, & Tarule (1986) Women's Ways of Knowing. The findings suggest that women understand their sexual experiences through informal sex education background, public sexual identity, and private sexual identity. These identities are understood through silence and received knowledge in the women's lived experiences and ownership of knowledge. The findings also suggest a model for college women's sexual identity development and how higher education can develop successful strategies to empower women and enlighten their educational experiences to assist in their academic persistence.
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Mapa, Claudine E. "Identification of Deubiquitinating Enzymes that Control the Cell Cycle in Saccharomyces cerevisiae." eScholarship@UMMS, 2018. https://escholarship.umassmed.edu/gsbs_diss/1004.

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A large fraction of the proteome displays cell cycle-dependent expression, which is important for cells to accurately grow and divide. Cyclical protein expression requires protein degradation via the ubiquitin proteasome system (UPS), and several ubiquitin ligases (E3) have established roles in this regulation. Less is understood about the roles of deubiquitinating enzymes (DUB), which antagonize E3 activity. A few DUBs have been shown to interact with and deubiquitinate cell cycle-regulatory E3s and their protein substrates, suggesting DUBs play key roles in cell cycle control. However, in vitro studies and characterization of individual DUB deletion strains in yeast suggest that these enzymes are highly redundant, making it difficult to identify their in vivo substrates and therefore fully understand their functions in the cell. To determine if DUBs play a role in the cell cycle, I performed a screen to identify specific DUB targets in vivo and then explored how these interactions contribute to cell cycle control. I conducted an in vivo overexpression screen to identify specific substrates of DUBs from a sample of UPS-regulated proteins and I determined that DUBs regulate different subsets of targets, confirming they display specificity in vivo. Five DUBs regulated the largest number of substrates, with Ubp10 stabilizing 40% of the proteins tested. Deletion of Ubp10 delayed the G1-S transition and reduced expression of Dbf4, a regulatory subunit of Cdc7 kinase, demonstrating Ubp10 is important for progression into S-phase. We hypothesized that compound deletion strains of these five DUBs would be deficient in key cellular processes because they regulated the largest number of cell cycle proteins from our screen. I performed genetic analysis to determine if redundancies exist between these DUBs. Our results indicate that most individual and combination deletion strains do not have impaired proliferation, with the exception of cells lacking UBP10. However, I observed negative interactions in some combinations when cells were challenged by different stressors. This implies the DUB network may activate redundant pathways only upon certain environmental conditions. While deletion of UBP10 impaired proliferation under standard growth conditions, I discovered that deletion of the proteasome-regulatory DUBs Ubp6 or Ubp14 rescues the cell cycle defect inubp10∆ cells. This suggests in the absence of Ubp10 substrates such as Dbf4 are rapidly degraded by the proteasome, but deletion of proteasome-associated DUBs restores cell cycle progression. Our work demonstrates that in unperturbed cells DUBs display specificity for their substrates in vivo and that a coordination of DUB activities promotes cell cycle progression.
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48

Ugolini, Carolyn Bennett. "Carlo Cattaneo: The Religiosity of a Relunctant Revolutionary." BYU ScholarsArchive, 2007. https://scholarsarchive.byu.edu/etd/1004.

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Carlo Cattaneo (1801-1869) would have been a remarkable man in any time period. He was interested in everything, and as a man of ideas was involved in the astonishing technological and stimulating political events of the nineteenth century. He encouraged the building of railways as a way to unite the Italian peninsula, and he was involved in connecting Italy to the rest of Europe through the St. Gothard Tunnel. An innovator of gas lighting in his native Milan, the great Lombard thinker was a prolific writer, and kept prodigious notes and copies of his correspondence. His economic and scientific involvement in the latest technology was emblematic of the intellectual strides he made. For example, he logically and rationally argued for racial and religious tolerance of the Jews over one hundred years before the enactment of the infamous Racial Laws in Fascist Italy. Today most know Carlo Cattaneo as the father of Italian federalism. During the Cinque Giornate insurrection in Milan in 1848, Carlo Cattaneo was an integral part of the war committee, and its spokesman. Although he had many liberal ideas about government and the rights of men, Carlo Cattaneo was a reluctant revolutionary, preferring exile in Switzerland over pledging allegiance to the Savoyard monarchy during the Risorgimento. Historians have almost unanimously declared that Carlo Cattaneo was anticlerical and irreligious. This was not true. CARLO CATTANEO: THE RELIGIOSITY OF A RELUCTANT REVOLUTIONARY examines the writings and the correspondence of Carlo Cattaneo, and concludes that the Cattanean opus is replete with Biblical references and allusions, Christian traditions and ideas. Historians have not taken the religiosity found in the writings of Carlo Cattaneo seriously. This thesis does.
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Masters, Harriet P. "A Study of the Southern Appalachian Granny-Woman Related to Childbirth Prevention Measures." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etd/1004.

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Documented as serving in the midwife capacity from the 1880s to the 1930s, the “granny-woman,” often was the only line of defense regarding childbirth support practices for many childbearing age women living in the region during the late nineteenth and early twentieth centuries. The early twentieth century saw the granny-women discredited and subject to elimination as a result of a purposeful campaign conducted by the male-dominated medical profession. Using knowledge of herbal remedies, the granny-woman played an integral part in the survival of the inhabitants of the region, especially related to childbirth. These centuries-old, herbal-based ministrations have been explored to aid in dispelling the erroneous conclusions related to the vital community role fulfilled by the Southern Appalachian granny-woman. Possessing knowledge of herbal-based childbirth prevention measures, the Southern Appalachian granny-woman rarely provided specifics related to the use of these measures by the women living in the region during that era.
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50

Нидченко, С. Н. "Устойчивость периодических решений нелинейных дифференциальных уравнений с запаздыванием : автореф. дис. ... канд. физ.-мат. наук: 01.01.02." Thesis, б. и, 2006. http://hdl.handle.net/10995/1004.

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