Relevant bibliographies by topics / (1,3;1,4)-beta-glucan

Academic literature on the topic '(1,3;1,4)-beta-glucan'

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Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "(1,3;1,4)-beta-glucan"

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Chang, Shu-Chieh, Rebecka Karmakar Saldivar, Pi-Hui Liang, and Yves S. Y. Hsieh. "Structures, Biosynthesis, and Physiological Functions of (1,3;1,4)-β-d-Glucans." Cells 10, no. 3 (February 27, 2021): 510. http://dx.doi.org/10.3390/cells10030510.

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(1,3;1,4)-β-d-Glucans, also named as mixed-linkage glucans, are unbranched non-cellulosic polysaccharides containing both (1,3)- and (1,4)-β-linkages. The linkage ratio varies depending upon species origin and has a significant impact on the physicochemical properties of the (1,3;1,4)-β-d-glucans. (1,3;1,4)-β-d-Glucans were thought to be unique in the grasses family (Poaceae); however, evidence has shown that (1,3;1,4)-β-d-glucans are also synthesized in other taxa, including horsetail fern Equisetum, algae, lichens, and fungi, and more recently, bacteria. The enzyme involved in (1,3;1,4)-β-d-glucan biosynthesis has been well studied in grasses and cereal. However, how this enzyme is able to assemble the two different linkages remains a matter of debate. Additionally, the presence of (1,3;1,4)-β-d-glucan across the species evolutionarily distant from Poaceae but absence in some evolutionarily closely related species suggest that the synthesis is either highly conserved or has arisen twice as a result of convergent evolution. Here, we compare the structure of (1,3;1,4)-β-d-glucans present across various taxonomic groups and provide up-to-date information on how (1,3;1,4)-β-d-glucans are synthesized and their functions.
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Cseh, A., K. Kruppa, I. Molnár, M. Rakszegi, J. Doležel, and M. Molnár-Láng. "Characterization of a new 4BS.7HL wheat–barley translocation line using GISH, FISH, and SSR markers and its effect on the β-glucan content of wheat." Genome 54, no. 10 (October 2011): 795–804. http://dx.doi.org/10.1139/g11-044.

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A spontaneous interspecific Robertsonian translocation was revealed by genomic in situ hybridization (GISH) in the progenies of a monosomic 7H addition line originating from a new wheat ‘Asakaze komugi’ × barley ‘Manas’ hybrid. Fluorescence in situ hybridization (FISH) with repetitive DNA sequences (Afa family, pSc119.2, and pTa71) allowed identification of all wheat chromosomes, including wheat chromosome arm 4BS involved in the translocation. FISH using barley telomere- and centromere-specific repetitive DNA probes (HvT01 and (AGGGAG)n) confirmed that one of the arms of barley chromosome 7H was involved in the translocation. Simple sequence repeat (SSR) markers specific to the long (L) and short (S) arms of barley chromosome 7H identified the translocated chromosome segment as 7HL. Further analysis of the translocation chromosome clarified the physical position of genetically mapped SSRs within 7H, with a special focus on its centromeric region. The presence of the HvCslF6 gene, responsible for (1,3;1,4)-β-d-glucan production, was revealed in the centromeric region of 7HL. An increased (1,3;1,4)-β-d-glucan level was also detected in the translocation line, demonstrating that the HvCslF6 gene is of potential relevance for the manipulation of wheat (1,3;1,4)-β-d-glucan levels.
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Ermawar, Riksfardini A., Helen M. Collins, Caitlin S. Byrt, Natalie S. Betts, Marilyn Henderson, Neil J. Shirley, Julian Schwerdt, Jelle Lahnstein, Geoffrey B. Fincher, and Rachel A. Burton. "Distribution, structure and biosynthetic gene families of (1,3;1,4)-β-glucan in Sorghum bicolor." Journal of Integrative Plant Biology 57, no. 4 (March 31, 2015): 429–45. http://dx.doi.org/10.1111/jipb.12338.

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ANTTILA, H., T. SONTAG-STROHM, and H. SALOVAARA. "Viscosity of beta-glucan in oat products." Agricultural and Food Science 13, no. 1-2 (December 4, 2008): 80. http://dx.doi.org/10.2137/1239099041838012.

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Oats contain 3-5% of mixed linked beta-glucan, or (1-3), (1-4) â-D-glucan, referred to hereafter as beta-glucan. Oat beta-glucan is a viscous, and soluble dietary fibre component. Soluble and viscous dietary fibres, including the beta-glucan present in oats are associated with two major health promoting effects, i.e. the attenuation of postprandial plasma glucose and insulin levels and the control of cholesterol. Increased viscosity in the intestine delays absorption of glucose and suppresses absorption of cholesterol and reabsorption of bile acids. In spite of its apparent key role physiologically the viscosity of beta-glucan has been discussed relatively little in terms of analytical procedures. In clinical studies performed with oats, the viscosity of beta-glucan has been properly documented in only a few cases. Viscosity of beta-glucan in foods and in the food digest depends on solubility, concentration and molecular weight. A food manufacturer aiming at health-promoting products must pay attention not only to sufficient concentration of beta-glucan (dose) in the raw material, but also to the processing methods that will ensure sufficient solubility of beta-glucan and minimize enzymatic or mechanical breakdown of the beta-glucan molecule. We have been working both with different food processes utilising oat fractions high in beta-glucan and with the development of a method for viscosity determination of the soluble beta-glucan fibre. This review discusses some of the aspects related to the development with a method that could predict the behaviour of beta-glucan in oat processing with respect to its anticipated physiological functions.;
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Gracia, Montilla-Bascón, Paul R. Armstrong, Han Rongkui, and Sorrells Mark. "Quantification of betaglucans, lipid and protein contents in whole oat groats (Avena sativa L.) using near infrared reflectance spectroscopy." Journal of Near Infrared Spectroscopy 25, no. 3 (June 2017): 172–79. http://dx.doi.org/10.1177/0967033517709615.

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Whole oat has been described as an important healthy food for humans due to its beneficial nutritional components. The positive health benefits of consuming oats as a whole-grain food are attributed in part to β-glucan, which has outstanding functional and nutritional properties. Near infrared reflectance spectroscopy is a powerful, fast, accurate and non-destructive analytical tool that can be substituted for some traditional chemical analysis. A total of 1728 single intact groats of six different oat varieties were scanned by near infrared spectroscopy to develop non-destructive predictions for (1,3;1,4)-β-D-glucan (β-glucan), protein and oil content in groats. Prediction models for single kernels were developed using partial least squares regression. Regression parameters between the chemical values, determined by wet-lab reference methods, and the predicted values determined from near infrared spectra, were verified by cross-validation and against data from a set of independent samples. The cross-validation correlation coefficients ( R2CV) for β-glucan, protein and oil were 0.83, 0.72 and 0.92, respectively, the root-mean-square error ranged from 0.25% to 0.60% for all compounds. Independent validation data had r2 values ranging from 0.69 to 0.95; root-mean-square error of prediction values (RMSEP) values were equal to or less than 0.52%, 0.62% and 0.27% for β-glucan, protein and oil, respectively. The data indicated that non-destructive screening of β-glucan, protein and oil contents in single kernels of dehulled oat grains from their near infrared spectra could be successfully used in breeding programs.
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Poutsiaka, DD, M. Mengozzi, E. Vannier, B. Sinha, and CA Dinarello. "Cross-linking of the beta-glucan receptor on human monocytes results in interleukin-1 receptor antagonist but not interleukin-1 production." Blood 82, no. 12 (December 15, 1993): 3695–700. http://dx.doi.org/10.1182/blood.v82.12.3695.3695.

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Abstract The beta-glucan receptor, found on monocytes and neutrophils, binds glucose polymers derived from fungi. Ligands for the receptor have various immunomodulatory effects, including increased microbicidal killing activity. We have investigated the effect of beta-glucans on the production of interleukin-1 (IL-1) and its naturally occurring inhibitor, the IL-1 receptor antagonist (IL-1Ra). Particulate beta- glucan induced IL-1Ra production from human peripheral blood mononuclear cells (PBMC) but did not stimulate IL-1 beta synthesis or gene expression in these same cells. Monomeric (soluble) beta-glucan did not induce IL-1Ra production. However, when preincubated with PBMC, monomeric beta-glucan significantly (P <.01) reduced particulate beta- glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta- glucan receptors is required for induction of IL-1Ra. In support of this, monomeric beta-glucan immobilized on plastic surfaces stimulated IL-1Ra production. Vitamin D3, which increases the functional capacity of beta-glucan receptors, increased IL-1Ra production induced by particulate beta-glucan, whereas dexamethasone suppressed IL-1Ra synthesis. Because of their differential effects on cytokine production, beta-glucans may be used to therapeutic advantage in the diseases in which IL-1 is implicated.
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Poutsiaka, DD, M. Mengozzi, E. Vannier, B. Sinha, and CA Dinarello. "Cross-linking of the beta-glucan receptor on human monocytes results in interleukin-1 receptor antagonist but not interleukin-1 production." Blood 82, no. 12 (December 15, 1993): 3695–700. http://dx.doi.org/10.1182/blood.v82.12.3695.bloodjournal82123695.

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The beta-glucan receptor, found on monocytes and neutrophils, binds glucose polymers derived from fungi. Ligands for the receptor have various immunomodulatory effects, including increased microbicidal killing activity. We have investigated the effect of beta-glucans on the production of interleukin-1 (IL-1) and its naturally occurring inhibitor, the IL-1 receptor antagonist (IL-1Ra). Particulate beta- glucan induced IL-1Ra production from human peripheral blood mononuclear cells (PBMC) but did not stimulate IL-1 beta synthesis or gene expression in these same cells. Monomeric (soluble) beta-glucan did not induce IL-1Ra production. However, when preincubated with PBMC, monomeric beta-glucan significantly (P <.01) reduced particulate beta- glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta- glucan receptors is required for induction of IL-1Ra. In support of this, monomeric beta-glucan immobilized on plastic surfaces stimulated IL-1Ra production. Vitamin D3, which increases the functional capacity of beta-glucan receptors, increased IL-1Ra production induced by particulate beta-glucan, whereas dexamethasone suppressed IL-1Ra synthesis. Because of their differential effects on cytokine production, beta-glucans may be used to therapeutic advantage in the diseases in which IL-1 is implicated.
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Christensen, Ulla, and Henrik Vibe Scheller. "Regulation of (1,3;1,4)-β-d-glucan synthesis in developing endosperm of barley lys mutants." Journal of Cereal Science 55, no. 1 (January 2012): 69–76. http://dx.doi.org/10.1016/j.jcs.2011.10.005.

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Cory, Aron T., Monica Båga, Anthony Anyia, Brian G. Rossnagel, and Ravindra N. Chibbar. "Genetic markers for CslF6 gene associated with (1,3;1,4)-β-glucan concentration in barley grain." Journal of Cereal Science 56, no. 2 (September 2012): 332–39. http://dx.doi.org/10.1016/j.jcs.2012.02.003.

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Marcotuli, Ilaria, Pasqualina Colasuonno, Yves S. Y. Hsieh, Geoffrey B. Fincher, and Agata Gadaleta. "Non-Starch Polysaccharides in Durum Wheat: A Review." International Journal of Molecular Sciences 21, no. 8 (April 22, 2020): 2933. http://dx.doi.org/10.3390/ijms21082933.

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Durum wheat is one of most important cereal crops that serves as a staple dietary component for humans and domestic animals. It provides antioxidants, proteins, minerals and dietary fibre, which have beneficial properties for humans, especially as related to the health of gut microbiota. Dietary fibre is defined as carbohydrate polymers that are non-digestible in the small intestine. However, this dietary component can be digested by microorganisms in the large intestine and imparts physiological benefits at daily intake levels of 30–35 g. Dietary fibre in cereal grains largely comprises cell wall polymers and includes insoluble (cellulose, part of the hemicellulose component and lignin) and soluble (arabinoxylans and (1,3;1,4)-β-glucans) fibre. More specifically, certain components provide immunomodulatory and cholesterol lowering activity, faecal bulking effects, enhanced absorption of certain minerals, prebiotic effects and, through these effects, reduce the risk of type II diabetes, cardiovascular disease and colorectal cancer. Thus, dietary fibre is attracting increasing interest from cereal processors, producers and consumers. Compared with other components of the durum wheat grain, fibre components have not been studied extensively. Here, we have summarised the current status of knowledge on the genetic control of arabinoxylan and (1,3;1,4)-β-glucan synthesis and accumulation in durum wheat grain. Indeed, the recent results obtained in durum wheat open the way for the improvement of these important cereal quality parameters.
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Dissertations / Theses on the topic "(1,3;1,4)-beta-glucan"

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Garcia, Gimenez Guillermo. "Regulation of (1,3;1,4)-β-glucan synthesis in barley (Hordeum vulgare L.)." Thesis, University of Dundee, 2019. https://discovery.dundee.ac.uk/en/studentTheses/fc549364-8ed1-4840-ad6c-b868cfebb28b.

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Schreiber, Miriam. "Identification of genes involved in (1,3;1,4)-β-glucan synthesis in barley (Hordeum vulgare)." Thesis, University of Dundee, 2016. https://discovery.dundee.ac.uk/en/studentTheses/5e459c3c-9ba7-4fb6-a33b-02577ea185fa.

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Vink, Edwin. "1,6-[beta]-glucan synthesis in Saccharomyces cerevisiae." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2003. http://dare.uva.nl/document/66912.

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Miller, S. Shea. "Oat beta-glucan: Biochemistry, structure and genetic variation." Thesis, University of Ottawa (Canada), 1992. http://hdl.handle.net/10393/7507.

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An enzymatic assay designed for measurement of $\beta$-glucan in barley was modified to allow measurement of total $\beta$-glucan content in oats by manipulating the grinding and incubation protocol. Using the modified enzymatic assay, the range of genetic and environmental variation of $\beta$-glucan content in Canadian domestic and breeder's lines of oats was assessed using several cultivars grown in 5 locations in eastern Canada in 3 growing seasons. Analysis of variance indicated that the predominant source of variation was genetic. A second assay using Flow Injection Analysis (FIA) to measure $\beta$-glucan was also evaluated. Although a high correlation was observed for the results of the two methods (r = 0.90), the results obtained using FIA tended to be somewhat lower than those obtained using the modified enzymatic assay: the enzymatic assay was judged to be more accurate for estimation of total $\beta$-glucan in oats. Nevertheless, because of its greater speed and simplicity, FIA would be a valuable screening tool for routine-applications. Using the enzymatic assay, $\beta$-glucan content was also measured in 18 primitive species of Avena to evaluate possible sources of germplasm for expanding the range of $\beta$-glucan content currently available in domestic cultivars. A comparison of $\beta$-glucan content with protein content, oil content and thousand kernel weight in domestic oats showed that these quality parameters are independent of $\beta$-glucan concentration in oats. Scanning microspectrofluorometry was used to map $\beta$-glucan distribution in single kernels of oats: differences were observed within single kernels, and also among kernels from different cultivars of oats. Microscopic examination suggests that the different distribution patterns are due to differences in cell wall thickness adjacent to the germ and around the periphery of the kernel, and also to differences in cell size and shape in the central endosperm. A high $\beta$-glucan (Marion) and a low $\beta$-glucan oat cultivar (OA516-2) were selected for isolation and preliminary characterization of the endosperm cell walls, which are the major source of $\beta$-glucan in the oat kernel. It was concluded that the differences in $\beta$-glucan content that were observed in whole groats were not due to differences in the composition of isolated endosperm cell walls, but to variation in cell size and cell wall thickness in different areas of the groats. (Abstract shortened by UMI.)
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Chan, Wing-keung. "The immunomodulatory effects of purified [beta]-glucans and [beta]-glucan containing herbs /." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38724674.

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Junginger, Ben. "Identifizierung, Klonierung und Sequenzierung der 1,3-[beta]-D-Glucan-Synthetase [1,3-Beta-D-Glucan-Synthetase] bei der humanpathogenen Hefespezies Candida glabrata." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971464154.

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Shah, Vaibhav. "Molecular and functional analysis of beta-glucan-mediated microglial activation." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1229705831.

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Paris, Robert L. "Potential of Hulless Winter Barley as an Improved Feed Crop." Diss., Virginia Tech, 2000. http://hdl.handle.net/10919/27228.

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This research was conducted to determine the potential of hulless winter barley (Hordeum vulgare L.) as an improved feed crop in the mid-Atlantic region. Winter barley is an excellent crop in rotation with soybean (Glycine max L.); however, production of winter barley during the past few years has decreased mainly due to low market prices, even though the mid-Atlantic region is a feed grain deficient area. Therefore, value added traits need to be developed in order for barley production to continue in the region. In the first part of this study, the objectives were to: (i) evaluate the agronomic performance and potential of six experimental hulless winter barley lines compared with two commercial hulled cultivars; (ii) determine and compare fiber, b-glucan, protein, and fat concentrations, and true metabolizable energy, corrected for nitrogen (TMEn) among these genotypes; and (iii) evaluate the genetic potential of winter hulless barley accessions from the world collection for use as parents in hulless breeding programs. Six hulless lines all derived from the cross VA75-42-45/SC793556//CI2457 were acquired from Clemson University in South Carolina. The six lines were evaluated for yield, test weight, heading date, plant height, and lodging. These hulless lines along with two hulled cultivars were planted in replicated yield plots in four states with a total of eight locations, and were managed according to standard recommended practices. Grain from each of the hulless lines and hulled checks, along with that of Trical 498 triticale (X Triticosecale) and Jackson wheat (Triticum aestivum L.) were analyzed for fiber, b-glucan, fat, protein, and ash concentration, and TMEn value. Eight hundred and seven winter or facultative habit hulless barley lines were obtained from the USDA-ARS National Small Grains Collection in Aberdeen, ID. These lines were screened for reaction type to races 8 and 30 of barley leaf rust (Puccinia hordei) and to a composite population of powdery mildew (Blumeria graminis f. sp. hordei). These accessions also were planted in observation rows to evaluate heading date, plant height, lodging, and seed threshability. The hulless lines yielded 23% less, but had 13% higher test weights than the hulled check cultivars. There was no difference between hulled and hulless barley in heading date and plant height. Hulless lines had a higher protein and lower fiber concentration than hulled barley. They also had higher b-glucan and fat concentrations than triticale or wheat. TMEn was similar between hulled and hulless barley, triticale, and wheat. Approximately 100 hulless barley lines from the world collection were selected for potential use as parents among 800 accessions tested, based on evaluations of lodging, plant height, threshability, and seed color. In the second part of the study the objectives were to determine the effects of (i) hulled and hulless barley, and (ii) b-glucanase on the performance of broilers fed different diets from 21 to 42 days of age. Diets comprised of 30% hulless or hulled barley, and a standard corn (Zea mays)/soybean meal diet with and without b-glucanase enzyme were evaluated to determine the effects of barley on gut viscosity, carcass weight, gain, percent shell, and feed efficiency in 21 to 42 day old broilers. In the first year, diets comprised of hulless lines SC890573 and SC860972, and the hulled cultivar Callao were compared to a standard check diet. In the second year SC860972 was replaced with SC880248 due to the inability to secure a sufficient amount of seed. Each year one hulled and two hulless barley diets were compared to a standard diet. Each diet was fed with and without enzyme, for a total of eight diets. Broilers 21 days of age were fed the diets until day 42 when they were processed. There was a significant decrease (P<0.05) in gut viscosity of birds fed diets with enzyme compared to birds fed diets without enzyme; however, gut viscosity did not affect weight gain or percent shell. Barley substituted at the 30% level did not have a significant effect on broiler performance, nor did the addition of enzyme. Absence of enzyme effect was attributed to bird age, since older birds are able to hydrolyze b-glucan more effectively than juveniles. The potential of hulless barley as an improved feed source for the poultry and swine industry is great for the mid-Atlantic region. Increases in grain yield are currently being realized through focused breeding efforts, and hulless lines exhibit positive nutritional components that combine favorable attributes of both wheat and hulled barley. Barley substituted at the 30% level in the diets of broilers did not cause any detrimental effects. Addition of hulless barley may potentially lead to a reduction in cost per pound of gain of broilers, and provide an alternative crop for mid-Atlantic region grain producers and feeders.
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Dai, Huaien. "Structural and functional studies of interactions between [beta]-1,3-glucan and the N-terminal domains of [beta]-1,3-glucan recognition proteins involved in insect innate immunity." Diss., Kansas State University, 2013. http://hdl.handle.net/2097/15286.

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Doctor of Philosophy
Department of Biochemistry
Ramaswamy Krishnamoorthi
Insect [beta]-1,3-glucan recognition protein ([beta]GRP), a soluble receptor in the hemolymph, binds to the surfaces of bacteria and fungi and activates serine protease cascades that promote destruction of pathogens by means of melanization or expression of antimicrobial peptides. Delineation of mechanistic details of these processes may help develop strategies to control insect-borne diseases and economic losses. Multi-dimensional nuclear magnetic resonance (NMR) techniques were employed to solve the solution structure of the Indian meal moth (Plodia interpunctella) [beta]GRP N-terminal domain (N-[beta]GRP), which is sufficient to activate the prophenoloxidase (proPO) pathway resulting in melanin formation. This is the first determined three-dimensional structure of N-[beta]GRP, which adopts an immunoglobulin fold. Addition of laminarin, a [beta]-1,3 and [beta]-1,6 link-containing glucose polysaccharide (∼6 kDa) that activates the proPO pathway, to N-[beta]GRP results in the loss of NMR cross-peaks from the backbone [subscript]1[subscript]5N-[subscript]1H groups of the protein, suggesting the formation of a large complex. Analytical ultracentrifugation (AUC) studies of formation of the N-[beta]GRP:laminarin complex show that ligand binding induces self-association of the protein-carbohydrate complex into a macro structure, likely containing six protein and three laminarin molecules (∼102 kDa). The macro complex is quite stable, as it does not undergo dissociation upon dilution to submicromolar concentrations. The structural model thus derived from this study for the N-[beta]GRP:laminarin complex in solution differs from the one in which a single N-[beta]GRP molecule has been proposed to bind to a triple-helical form of laminarin on the basis of a X-ray crystal structure of the N-[beta]GRP:laminarihexaose complex. AUC studies and phenoloxidase activation measurements made with designed mutants of N-[beta]GRP indicate that electrostatic interactions between the ligand-bound protein molecules contribute to the stability of the N-[beta]GRP:laminarin complex and that a decreased stability results in a reduction of proPO activation. These novel findings suggest that ligand-induced self-association of the [beta]GRP:[beta]-1,3-glucan complex may form a platform on a microbial surface for recruitment of downstream proteases, as a means of amplification of the pathogen recognition signal. In the case of the homolog of GNBPA2 from Anopheles gambiae, the malaria-causing Plasmodium carrier, multiligand specificity was characterized, suggesting a functional diversity of the immunoglobulin domain structure.
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Van, der Merwe Laurianne. "UDP-glucose: [beta]-(1-3)-glucan (paramylon) synthase from Euglena gracillis /." Link to the online version, 2007. http://hdl.handle.net/10019/722.

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Books on the topic "(1,3;1,4)-beta-glucan"

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Beta glucan: Nature's secret. Louisville, Kentucky: Vaclav Vetvicka, 2011.

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Antifungal drugs: (1,3) [beta]-glucan synthase inhibitors. New York: Springer, 1995.

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Lyly, Marika. Added [beta]-glucan as a source of fibre for consumers. Espoo, Finland: VTT Technical Research Centre of Finland, 2006.

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What is Beta Glucan? Safe Goods Publishing, 2001.

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Gürünlü, Betül. Medical Applications of Beta-Glucan. Bentham Science Publishers, 2021.

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Vetvicka, Vaclav, and Miroslav Novak, eds. Biology and Chemistry of Beta Glucan. BENTHAM SCIENCE PUBLISHERS, 2012. http://dx.doi.org/10.2174/97816080521031110101.

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Aoe, Seiichiro, Tatsuya Morita, and Naohito Ohno, eds. Beta-Glucan in Foods and Health Benefits. MDPI, 2022. http://dx.doi.org/10.3390/books978-3-0365-5108-1.

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Vetvicka, Vaclav, and Miroslav Novak, eds. Series Title: Biology and Chemistry of Beta Glucan Volume Title: Beta-Glucan, Structure, Chemistry and Specific Application. BENTHAM SCIENCE PUBLISHERS, 2013. http://dx.doi.org/10.2174/97816080526081130201.

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Publications, ICON Health. Beta-Glucan - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References. ICON Health Publications, 2004.

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Lan-Pidhainy, Xiaomiao. The physicochemical properties of oat beta-glucan and its ability to attenuate postprandial glycaemic response. 2006.

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Book chapters on the topic "(1,3;1,4)-beta-glucan"

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Dangi, Priya, Nisha Chaudhary, Riya Joshi, and Saranya Prabha. "Beta-glucan (β-glucan)." In Handbook of Cereals, Pulses, Roots, and Tubers, 133–48. Boca Raton: CRC Press, 2021. http://dx.doi.org/10.1201/9781003155508-9.

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Bährle-Rapp, Marina. "Oat Beta Glucan." In Springer Lexikon Kosmetik und Körperpflege, 382. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_7045.

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Schomburg, Dietmar, and Dörte Stephan. "1,3-beta-Glucan synthase." In Enzyme Handbook 12, 261–66. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61117-9_47.

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Schomburg, Dietmar, and Margit Salzmann. "Glucan 1, 3-beta-glucosidase." In Enzyme Handbook 4, 335–42. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-84437-9_49.

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Schomburg, Dietmar, and Margit Salzmann. "Glucan 1, 4-beta-glucosidase." In Enzyme Handbook 4, 403–7. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-84437-9_64.

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Schomburg, Dietmar, and Dörte Stephan. "1,3-beta-D-Glucan phosphorylase." In Enzyme Handbook 12, 493–95. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61117-9_100.

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Schomburg, Dietmar, and Margit Salzmann. "Glucan endo-1, 3-beta-glucosidase." In Enzyme Handbook 4, 241–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-84437-9_30.

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Schomburg, Dietmar, and Margit Salzmann. "Glucan endo-1, 2-beta-glucosidase." In Enzyme Handbook 4, 391–93. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-84437-9_61.

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Schomburg, Dietmar, and Margit Salzmann. "Glucan endo-1, 6-beta-glucosidase." In Enzyme Handbook 4, 409–13. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-84437-9_65.

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Benlier, Necla, Selin Sayin, Zafer Cetin, Mehtap Ozkur, and E. Ilker Saygili. "Dietary Fibers/Beta-Glucan and Cancer." In Food Bioactive Ingredients, 569–90. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74035-1_21.

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Conference papers on the topic "(1,3;1,4)-beta-glucan"

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Chang, Ilhan, and Gye-Chun Cho. "Elastic Wave Behaviors of Beta-Glucan Biopolymer-Treated Residual Soil." In Geo-Congress 2014. Reston, VA: American Society of Civil Engineers, 2014. http://dx.doi.org/10.1061/9780784413272.153.

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Falch, Berit H., Terje Espevik, and Bjorn T. Stokke. "(1 --> 3)-BETA-D-GLUCAN STRUCTURES AND IMMUNOSTIMULATION IN VITRO." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.375.

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Rakebrandt, M., and A. K. Siwicki. "Effect of Brewersʼ Yeast Beta-Glucan Supplementation on Immune Parameters in Horses." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759354.

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Sandula, Jozef, Darina Slamenova, Livia Krizkova, Juraj Labaj, Grigorij Kogan, Juraj Krajcovic, and Vladimir Velebny. "ANTIGENOTOXIC AND ANTIOXIDATIVE EFFECTS OF FUNGAL (1->3)-BETA-D-GLUCAN DERIVATIVES." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.676.

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Carmona Porquera, Eva M., and Andrew H. Limper. "Pneumocystis Beta-glucan Induces Activation Of The Human IL-23-IL-17 Axis." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5215.

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Shen, Ruiling, and Fengli Cai. "The Effects of Oat beta-Glucan on the Hypoglycemic of Type 2 Diabetic Mice." In 2010 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2010. http://dx.doi.org/10.1109/icbbe.2010.5516500.

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Gorden, Keith. "Abstract 2834: Identification of a critical level of anti-beta glucan IgG antibody necessary for response to soluble beta-glucan therapy and its application as a biomarker for analysis in clinical trials." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2834.

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Dong, Jilin, Ying Wang, and Ruiling Shen. "Notice of Retraction: The Oat beta-Glucan Affects Mice Intestinal Morphology Similarly to Other Oat Products." In 2011 5th International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2011. http://dx.doi.org/10.1109/icbbe.2011.5781623.

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Fan, Teresa W.-M., Andrew N. Lane, Jun Yan, Richard M. Higashi, Jeremiah T. Martin, and Michael Bousamra. "Abstract 4271: Beta-glucan activates macrophages in human NSCLC demonstrated by Stable Isotope Resolved Metabolomics (SIRM)." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-4271.

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Kim, Min-Ji, Jung-Yeon Yoo, Sang-Gyu Hwang, Kwang-Chul Ahn, Jung Hee Joo, Chang-Hoon Kim, Jee Hyun Lee, et al. "Beta-Glucan Mediates House Dust Mite-Induced Allergic Rhinitis Via TLR2/DUOX2 In Airway Epithelial Cells." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4400.

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Reports on the topic "(1,3;1,4)-beta-glucan"

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Moon, Sun Hee, Xi Feng, Hyon Yong Lee, Jihee Kim, and Dong Uk Ahn. Effect of Dietary Beta-Glucan on the Performance of Broilers. Ames (Iowa): Iowa State University, January 2017. http://dx.doi.org/10.31274/ans_air-180814-297.

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Blanton, R. L. Characterization of a 1,4-. beta. -D-glucan synthase from Dictyostelium discoideum. Office of Scientific and Technical Information (OSTI), January 1992. http://dx.doi.org/10.2172/5403431.

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Blanton, R. L. Characterization of a 1,4-{beta}-D-glucan synthase from Dictyostelium. Final technical report. Office of Scientific and Technical Information (OSTI), February 1996. http://dx.doi.org/10.2172/179232.

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Carpita, Nicholas C. Identifying the catalytic components of cellulose synthase and the maize mixed-linkage beta-glucan synthase. Office of Scientific and Technical Information (OSTI), April 2009. http://dx.doi.org/10.2172/951273.

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Schwartz, Bertha, Vaclav Vetvicka, Ofer Danai, and Yitzhak Hadar. Increasing the value of mushrooms as functional foods: induction of alpha and beta glucan content via novel cultivation methods. United States Department of Agriculture, January 2015. http://dx.doi.org/10.32747/2015.7600033.bard.

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Abstract:
During the granting period, we performed the following projects: Firstly, we differentially measured glucan content in several pleurotus mushroom strains. Mushroom polysaccharides are edible polymers that have numerous reported biological functions; the most common effects are attributed to β-glucans. In recent years, it became apparent that the less abundant α-glucans also possess potent effects in various health conditions. In our first study, we explored several Pleurotus species for their total, β and α-glucan content. Pleurotuseryngii was found to have the highest total glucan concentrations and the highest α-glucans proportion. We also found that the stalks (stipe) of the fruit body contained higher glucan content then the caps (pileus). Since mushrooms respond markedly to changes in environmental and growth conditions, we developed cultivation methods aiming to increase the levels of α and β-glucans. Using olive mill solid waste (OMSW) from three-phase olive mills in the cultivation substrate. We were able to enrich the levels mainly of α-glucans. Maximal total glucan concentrations were enhanced up to twice when the growth substrate contained 80% of OMSW compared to no OMSW. Taking together this study demonstrate that Pleurotuseryngii can serve as a potential rich source of glucans for nutritional and medicinal applications and that glucan content in mushroom fruiting bodies can be further enriched by applying OMSW into the cultivation substrate. We then compared the immune-modulating activity of glucans extracted from P. ostreatus and P. eryngii on phagocytosis of peripheral blood neutrophils, and superoxide release from HL-60 cells. The results suggest that the anti-inflammatory properties of these glucans are partially mediated through modulation of neutrophileffector functions (P. eryngiiwas more effective). Additionally, both glucans dose-dependently competed for the anti-Dectin-1 and anti-CR3 antibody binding. We then tested the putative anti-inflammatory effects of the extracted glucans in inflammatory bowel disease (IBD) using the dextran sulfate sodium (DSS)–induced model in mice. The clinical symptoms of IBD were efficiently relieved by the treatment with two different doses of the glucan from both fungi. Glucan fractions, from either P. ostreatus or P. eryngii, markedly prevented TNF-α mediated inflammation in the DSS–induced inflamed intestine. These results suggest that there are variations in glucan preparations from different fungi in their anti-inflammatory ability. In our next study, we tested the effect of glucans on lipopolysaccharide (LPS)-induced production of TNF-α. We demonstrated that glucan extracts are more effective than mill mushroom preparations. Additionally, the effectiveness of stalk-derived glucans were slightly more pronounced than of caps. Cap and stalk glucans from mill or isolated glucan competed dose-dependently with anti-Dectin-and anti-CR-3 antibodies, indicating that they contain β-glucans recognized by these receptors. Using the dextran sulfate sodium (DSS)-inflammatory bowel disease mice model, intestinal inflammatory response to the mill preparations was measured and compared to extracted glucan fractions from caps and stalks. We found that mill and glucan extracts were very effective in downregulatingIFN-γ and MIP-2 levels and that stalk-derived preparations were more effective than from caps. The tested glucans were equally effective in regulating the number of CD14/CD16 monocytes and upregulating the levels of fecal-released IgA to almost normal levels. In conclusion, the most effective glucans in ameliorating some IBD-inflammatory associated symptoms induced by DSS treatment in mice were glucan extracts prepared from the stalk of P. eryngii. These spatial distinctions may be helpful in selecting more effective specific anti-inflammatory mushrooms-derived glucans. We additionally tested the effect of glucans on lipopolysaccharide-induced production of TNF-α, which demonstrated stalk-derived glucans were more effective than of caps-derived glucans. Isolated glucans competed with anti-Dectin-1 and anti-CR3 antibodies, indicating that they contain β-glucans recognized by these receptors. In conclusion, the most effective glucans in ameliorating IBD-associated symptoms induced by DSS treatment in mice were glucan extracts prepared from the stalk of P. eryngii grown at higher concentrations of OMSW. We conclude that these stress-induced growing conditions may be helpful in selecting more effective glucans derived from edible mushrooms. Based on the findings that we could enhance glucan content in Pleurotuseryngii following cultivation of the mushrooms on a substrate containing different concentrations of olive mill solid waste (OMSW) and that these changes are directly related to the content of OMSW in the growing substrate we tested the extracted glucans in several models. Using dextran sulfate sodium (DSS)–inflammatory bowel disease (IBD) mice model, we measured the colonic inflammatory response to the different glucan preparations. We found that the histology damaging score (HDS) resulting from DSS treatment reach a value of 11.8 ± 2.3 were efficiently downregulated by treatment with the fungal extracted glucans, glucans extracted from stalks cultivated at 20% OMSWdownregulated to a HDS value of 6.4 ± 0.5 and at 80% OMSW showed the strongest effects (5.5 ± 0.6). Similar downregulatory effects were obtained for expression of various intestinal cytokines. All tested glucans were equally effective in regulating the number of CD14/CD16 monocytes from 18.2 ± 2.7 % for DSS to 6.4 ± 2.0 for DSS +glucans extracted from stalks cultivated at 50% OMSW. We finally tested glucans extracted from Pleurotuseryngii grown on a substrate containing increasing concentrations of olive mill solid waste (OMSW) contain greater glucan concentrations as a function of OMSW content. Treatment of rat Intestinal epithelial cells (IEC-6) transiently transfected with Nf-κB fused to luciferase demonstrated that glucans extracted from P. eryngii stalks grown on 80% OMSWdownregulatedTNF-α activation. Glucans from mushrooms grown on 80% OMSW exerted the most significant reducing activity of nitric oxide production in lipopolysaccharide (LPS) treated J774A.1 murine macrophages. The isolated glucans were tested in vivo using the Dextran Sodium Sulfate (DSS) induced colitis in C57Bl/6 mice and found to reduce the histology damaging score resulting from DSS treatment. Expression of various intestinal cytokines were efficiently downregulated by treatment with the fungal extracted glucans. We conclude that the stress-induced growing conditions exerted by OMSW induces production of more effective anti-inflammatory glucans in P. eryngii stalks.
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Blanton, R. L. Characterization of a 1,4-{beta}-D-glucan synthase from Dictyostelium discoideum. Progress report, May 1990--January 1992. Office of Scientific and Technical Information (OSTI), January 1992. http://dx.doi.org/10.2172/10138930.

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Ross, Gordon D. Development of an Oral Barley Beta-Glucan Adjuvant That Augments the Tumoricidal Activity of Antibodies or Vaccines Used for the Immunotherapy of Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, July 2003. http://dx.doi.org/10.21236/ada417775.

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