Academic literature on the topic '030503 Organic Chemical Synthesis'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic '030503 Organic Chemical Synthesis.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "030503 Organic Chemical Synthesis"
Mori, Kenji. "Organic Synthesis and Chemical Ecology." Accounts of Chemical Research 33, no. 2 (February 2000): 102–10. http://dx.doi.org/10.1021/ar990006x.
Full textYoshimura, Fumihiko, Ryusei Itoh, Makoto Torizuka, Genki Mori, and Keiji Tanino. "Chemical Synthesis of Brasilicardins." Journal of Synthetic Organic Chemistry, Japan 78, no. 11 (November 1, 2020): 1085–93. http://dx.doi.org/10.5059/yukigoseikyokaishi.78.1085.
Full textYoshino, Teruo. "Chemical Synthesis of Glycosphingolipids." Trends in Glycoscience and Glycotechnology 2, no. 8 (1990): 486–97. http://dx.doi.org/10.4052/tigg.2.486.
Full textMatsuoka, Koji. "Chemical Synthesis of Cellulose." Trends in Glycoscience and Glycotechnology 8, no. 44 (1996): 441–42. http://dx.doi.org/10.4052/tigg.8.441.
Full textCOOK, M., M. EUGENIO, R. GELINAS, R. MIKULSKI, and P. N. TRINH. "ChemInform Abstract: Hydrides for Organic Chemical Synthesis." ChemInform 27, no. 17 (August 5, 2010): no. http://dx.doi.org/10.1002/chin.199617286.
Full textMori, Kenji. "ChemInform Abstract: Organic Synthesis and Chemical Ecology." ChemInform 31, no. 17 (June 8, 2010): no. http://dx.doi.org/10.1002/chin.200017262.
Full textYoshimura, Fumihiko, Keiji Tanino, and Masaaki Miyashita. "Chemical Synthesis of Zoanthamine Alkaloids." Journal of Synthetic Organic Chemistry, Japan 71, no. 2 (2013): 124–35. http://dx.doi.org/10.5059/yukigoseikyokaishi.71.124.
Full textPefkianakis, Eleftherios K., Georgios Sakellariou, and Georgios C. Vougioukalakis. "Chemical synthesis of graphene nanoribbons." Arkivoc 2015, no. 3 (February 26, 2015): 167–92. http://dx.doi.org/10.3998/ark.5550190.p008.995.
Full textImamura, Akihiro, and Todd Lowary. "Chemical Synthesis of Furanose Glycosides." Trends in Glycoscience and Glycotechnology 23, no. 131 (2011): 134–52. http://dx.doi.org/10.4052/tigg.23.134.
Full textZhang, Yunqin, and Guozhi Xiao. "Chemical synthesis of TMG-chitotriomycin." Journal of Carbohydrate Chemistry 40, no. 7-9 (November 22, 2021): 327–38. http://dx.doi.org/10.1080/07328303.2021.2009504.
Full textDissertations / Theses on the topic "030503 Organic Chemical Synthesis"
Weinstein, Randy D. (Randy David) 1971. "Organic synthesis in suppercritical carbon dioxide." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/9652.
Full textIncludes bibliographical references (leaves 185-201).
Many industrially important synthesis reactions are carried out in liquid solvents such as aromatic compounds, chlorinated hydrocarbons, and other organic liquids which pose environmental and health hazards either because of their toxicity or their persistence in the environment. Hence proper disposal of these solvents and the prevention of accidental releases or routine emissions cause serious difficulties and costs for the industries who use them. An approach to mitigating these problems is to use alternative solvents that are environmentally benign or that can be completely recycled in a closed-loop process. One such alternative solvent is supercritical carbon dioxide. Although supercritical carbon dioxide is used in many industrial extraction and chromatography processes it is not widely used as a reaction medium and its effects on chemical reactions are not well understood. The goals of this research were to gain a better understanding as to the effect of supercritical carbon dioxide through a systematic investigation of solvent conditions on the rates and selectivities of several model organic synthesis reactions. In addition, the use of environmentally benign catalysts/promoters in gaseous and supercritical carbon dioxide as well as developing chemical pathways in which carbon dioxide can act as a solvent as well as a reactant were explored to expand the possible industrial applications. In the pursuit of these goals, new reactors, feed and sampling procedures, as well as new chemical pathways were explored. Specifically, the bimolecular rate constants of the Diets-Alder reaction of ethyl acrylate and cyclopentadiene were measured in supercritical carbon dioxide from 38 to 88 °C and pressures from 80 to 210 bar. At constant temperature, the rate increased with pressure or density and was most dramatic near the critical point of carbon dioxide. A traditional Arrhenius expression was used to correlate the kinetic data at a constant system density. All of the rate constant data were normalized to the rate constant at the same temperature and at a fixed density of 0.5 g/cm3. These normalized rate constants over a range of temperatures then collapsed on a single line as a function of density. Rates could be predicted using a bimolecular Arrhenius expression with the pre-exponential term having a linear dependence on density. Theoretically, a rigorous transition state theory rate constant was derived and used to gain a better understanding of the non-ideal solvent-reactant-product interactions which could influence the rate. Effects of pressure/density and temperature on the regio- and stereo- selectivity of several Diels-Alder reactions were explored. Regioselectivity did not correlate well with density changes; however, stereoselectivity did. As pressure was increased, the endo isomer always increased in the supercritical region. The stereoselectivity changes were modeled using temperature and density as the model inputs. Again, the rigorous transition state theory rate constant was used to explain the observed selectivity changes. Phase behavior played an important role in these investigations, sometimes influencing selectivity. The design and construction of reactors with a sapphire window allowed for visual access into the reaction environment to monitor phase behavior. Silica was shown to increase the rate and selectivity of several Diels-Alder reactions in carbon dioxide. Pressure/density effects were explored using the reaction of methyl vinyl ketone and penta-1,3-diene. Pressure did not affect the selectivity; however, it had a large effect on the yield of the reaction. This was discovered to be caused by the change in phase partitioning of the reactants between the fluid phase and the solid surface as pressure was changed. Adsorption isotherms at various pressures and temperatures were found. Because of the non-ideal system, the thermodynamic effect of temperature on the adsorption equilibrium needed to be derived. The effect of temperature on the adsorption was found at constant pressure. Although an enthalpy of adsorption could be determined, the presence of non-ideal phase behavior complicates its interpretation. In general, the adsorption enthalpy consists of partial molar enthalpies of both species (reactant and carbon dioxide) on/in both phases (solid/fluid). At constant density, the effect of temperature allows for the direct calculation of the entropy of adsorption. This term is affected by the partial molar entropies of both species on/in both phases. Three different carboxylation reactions were investigated in supercritical carbon dioxide. The Kolbe-Schmitt reaction (direct carboxylation of a phenolate salt) was found to proceed at high yields in supercritical carbon dioxide. Attempts at lowering the temperature of reaction by using cosolvents was not successful. Temperature and pressure had minimal effect on the selectivity of the reaction. Two other carboxylation reactions were examined. In the first study, the homogeneous catalyzed caboxylation of an allylsilane was performed in supercritical carbon dioxide. Pressure did not appear to affect the reaction; however, there was a narrow temperature range which allowed the reaction to proceed. At best, yields were only 15%. The final reaction studied was the catalyzed (Lewis acid) carboxylation of an alkene by carbon dioxide. Unfortunately it did not proceed in supercritical carbon dioxide to any measurable extent at temperatures of 40 to 350 °C with and without the presence of various catalysts.
by Randy D. Weinstein.
Ph.D.
Kimani, Flora, and Flora Kimani. "Triazabutadiene Chemistry in Organic Synthesis and Chemical Biology." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/620986.
Full textRickards, Andrew M. J. "Hygroscopic organic aerosol : thermodynamics, kinetics, and chemical synthesis." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686238.
Full textMcMurray, Brian Thomas. "Chemical and enzymatic synthesis of organosulphur compounds." Thesis, Queen's University Belfast, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359111.
Full textLee, Wen-Hsuan Ph D. Massachusetts Institute of Technology. "Development of microreactor setups for microwave organic synthesis." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/98157.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (pages 135-140).
The main contribution of this work is the understanding of microwave heating and the microreactor design challenges involved through both chemical experiments and computational models. The original goal of this research is to develop a microreactor system in order to carry the microwave organic synthesis in continuous flow format and to understand the basic phenomena of microwave heating through accurate kinetic studies. Several heating issues were observed with the first microreactor setup, including an uneven temperature distribution across the microwave irradiated area and a temperature limitation that depends on the position of the reactor. To find the root of these problems, the electromagnetic field and the heat transfer scheme of the microwave system were modeled with COMSOL. The simulations show that there are three main causes to the heating issues: (1) the electric field has an inherent resonance structure and thus has an uneven magnitude within the microwave cavity, (2) the electric field changes with not only the material, but also the sizes and positions of the objects in the microwave cavity, (3) the air gaps in the microwave waveguide creates a large natural convection heat loss. The simulations gave us a deeper understanding of the microwave heating phenomena and were used to find the optimum design of the microreactor. A second multiple-layered glass reactor was designed accordingly to overcome the heating limitation and minimized the temperature unevenness. However, the non-uniform heating rate cannot be eliminated since it is inherent in the resonance structure of microwaves. Both the experimental results and the simulations of the final reactor show that even though the reactor can reach the desired temperature, the temperature range across the reactor could be up to 20 *C. In addition, it was found that the flow rate of the reaction greatly affects the thermal equilibrium of the reaction volume. Accurate temperature control is therefore still a challenge for kinetic studies to be feasible with the current single-mode microwave system. The benefit of microwave heating is therefore still in the qualitative screening of chemical compounds, a feature which was demonstrated with a Fischer-Indole screening in the final setup.
by Wen-Hsuan Lee.
Ph. D.
Murphy, Edward R. "Microchemical systems for rapid optimization of organic synthesis." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/36912.
Full textThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Includes bibliographical references (leaves 111-119).
In the chemistry laboratory, the desire to use smaller quantities of material to minimize both reagent cost and waste generation has driven chemists to develop new experimental techniques. The current approach to small scale experimentation has mostly been a simple reduction in the size of batch reaction apparatus. Working with these smaller volumes has increased the efficiency of experiments by accelerating the typically time consuming processes of heating, filtration, and drying. Furthermore, when working with hazardous materials, smaller scales minimize the exposure of a chemist to toxic materials and enable easier containment of potentially flammable or explosive systems. The use of microfluidic devices has shown several improvements when compared to traditional batch synthesis. The precise control of reaction conditions enabled within the microreactor format has proved advantageous for a wide range of single and multiphase reactions. Also, unlike conventional bench-top batch reactions, continuous microreactors are capable of producing both analytical and preparative quantities of material by simply changing the amount of reactor effluent collected.
(cont.) The aim of this work was to harness the microsystem advantages of improved safety and process intensification while demonstrating both improved quality and speed of data collection, especially for chemistries that were challenging to explore using standard laboratory techniques. This work required improvements to reactor design, packaging technologies, and experimental techniques in order to use microreactors as a platform for rapidly determining optimum reaction conditions as well as reaction kinetics. Three model reactions were selected to highlight the advantages of microchemical laboratory tools. The synthesis of oligosaccharides served as an example of rapid profiling of the effects of temperature and reaction time. Microreactors improved reaction optimization by reducing waste and dramatically increasing the rate of data collection. High-pressure carbonylation of aryl halides was also explored to characterize the effects of pressure, temperature, and various substrates on product yields. With microreactors, previously inaccessible reaction conditions were explored thus obtaining improved insights into the reaction mechanism.
(cont.) Finally, the production of sodium nitrotetrazolate was used to demonstrate the improved flexibility and safety of a modular microchemical system. The kinetics and pH effects for each step of the synthesis of this energetic compound were measured. This system was also optimized so that the microreactors used to characterize the reaction could be run in parallel as a production method.
by Edward Robert Murphy.
Ph.D.
Coley, Connor Wilson. "Computer assistance in organic synthesis planning and execution." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122903.
Full textThesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2019
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 409-432).
The identification and synthesis of molecules that exhibit a desired function is an essential part of addressing contemporary problems in science and technology. Small molecules are the predominant solution to challenges in the development of medicines, chemical probes, specialty polymers, and organocatalysts, among others. The typical discovery paradigm is an iterative process of designing candidate compounds, synthesizing those compounds, and testing their performance. The rate at which this process yields successful compounds can be limited by bottlenecks and mispredictions at all three stages and is plagued by inefficiencies, not the least of which is the manual nature of synthesis planning and execution. This thesis describes techniques to streamline the synthesis of small molecules in this context of pharmaceutical discovery from two perspectives: one experimental and the other using techniques in data science and machine learning.
Part I focuses on the time-, material-, and experimental-efficiency of data collection. It describes the development of an automated microfluidic reactor platform for studying physical and chemical processes at the micromole scale. Synthesis and purification of small molecule compound libraries are performed without human intervention at a scale suitable for a medicinal chemistry setting. Integration of online analytics enables efficient, closed-loop self-optimization using an optimal design of experiments algorithm to identify reaction conditions suitable for production-scale flow synthesis. To complement the generation of new data through automated experimentation, Part II is driven by the goal of applying existing reaction data to problems in synthesis and synthesis design. This includes the development of data-driven methodologies for the design and validation of small molecule synthetic routes.
An enabling factor in ensuring the feasibility of computationally-proposed reactions is the use of models to predict organic reaction outcomes in silico-also useful for impurity prediction-that leverage the flexibility in pattern recognition afforded by neural networks to understand chemical reactivity in the same way we might by reading the literature. Several predictive models are integrated into an overall framework for computer-aided synthesis planning that can rapidly propose routes to new molecules with the complexity of modern active pharmaceutical ingredients. As a final demonstration, machine learning assisted synthesis planning is brought together with laboratory automation to illustrate an accelerated approach to target-oriented flow synthesis. This is a proof-of-concept for how chemical development might one day occur with less human intervention.
by Connor Wilson Coley.
Ph. D.
Ph.D. Massachusetts Institute of Technology, Department of Chemical Engineering
Olugbenga, F. S. "Synthesis and physico-chemical studies on conjugated heteroenoid compounds." Thesis, Cardiff University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332625.
Full textWoodcock, Steven Robert. "Synthesis and chemical biology of nitrated lipids /." view abstract or download file of text, 2007. http://proquest.umi.com/pqdweb?did=1324377731&sid=2&Fmt=2&clientId=11238&RQT=309&VName=PQD.
Full textTypescript. Includes vita and abstract. Includes bibliographical references (leaves 195-207). Also available for download via the World Wide Web; free to University of Oregon users.
Collins, Beatrice Samora LeFanu. "New catalytic methods and strategies for chemical synthesis." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648556.
Full textBooks on the topic "030503 Organic Chemical Synthesis"
Corey, E. J. The logic of chemical synthesis. New York: John Wiley, 1989.
Find full textXue-Min, Cheng, ed. The logic of chemical synthesis. New York: John Wiley, 1995.
Find full textFieser, Mary. Reagents for organic synthesis. New York: Wiley, 1990.
Find full textFieser, Mary. Reagents for organic synthesis. New York: Wiley, 1989.
Find full textFieser, Mary. Reagents for organic synthesis. New York: Wiley, 1989.
Find full textFieser, Mary. Reagents for organic synthesis. New York: Wiley, 1992.
Find full textFieser, Mary. Reagents for organic synthesis. New York: Wiley, 1990.
Find full textFieser, Mary. Reagents for organic synthesis. New York: Wiley, 1986.
Find full textWalter, Leitner, and Jessop Philip G, eds. Chemical synthesis using supercritical fluids. Weinheim: Wiley-VCH, 1999.
Find full textBiomimetic organic synthesis. Weinheim: Wiley-VCH, 2011.
Find full textBook chapters on the topic "030503 Organic Chemical Synthesis"
Arigoni, Duilio. "Organic Synthesis and the Life Sciences." In Chemical Synthesis, 601–19. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0255-8_27.
Full textNorman, Richard, and James M. Coxon. "Chemical thermodynamics." In Principles of Organic Synthesis, 5–19. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2166-8_1.
Full textNorman, Richard, and James M. Coxon. "Chemical kinetics." In Principles of Organic Synthesis, 52–70. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2166-8_3.
Full textMontgomery, Lawrence K. "Chemical Synthesis and Crystal Growth Techniques." In Organic Conductors, 115–45. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780367811907-4.
Full textHanessian, Stephen. "Target-driven Organic Synthesis: Reflections on the Past, Prospects for the Future." In Chemical Synthesis, 61–90. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0255-8_3.
Full textLiu, Lei, Sam Danishefsky, and David Crich. "Chemical Synthesis of Proteins." In Organic Chemistry - Breakthroughs and Perspectives, 221–45. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664801.ch6.
Full textIkushima, Yutaka, and Masahiko Arai. "Stoichiometric Organic Reactions." In Chemical Synthesis Using Supercritical Fluids, 259–79. Weinheim, Germany: Wiley-VCH Verlag GmbH, 2007. http://dx.doi.org/10.1002/9783527613687.ch13.
Full textDraye, Micheline, Marion Chevallier, Vanille Quinty, Claire Besnard, Alexandre Vandeponseele, and Gregory Chatel. "CHAPTER 8. Sustainable Activation of Chemical Substrates Under Sonochemical Conditions." In Sustainable Organic Synthesis, 212–38. Cambridge: Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839164842-00212.
Full textŠtrukil, Vjekoslav, and Davor Margetic. "CHAPTER 7. Activation of Chemical Substrates Under Sustainable Conditions: Mechanochemistry." In Sustainable Organic Synthesis, 181–211. Cambridge: Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839164842-00181.
Full textWong, Chi-Huey, Yoshitaka Ichikawa, Tetsuya Kajimoto, Kevin K. C. Liu, David P. Dumas, Ying-Chih Lin, and Gary C. Look. "Chemical-Enzymatic Synthesis of Carbohydrates." In Microbial Reagents in Organic Synthesis, 35–42. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2444-7_3.
Full textConference papers on the topic "030503 Organic Chemical Synthesis"
Baxendale, Ian R. "Continuous Chemical Synthesis in Flow." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-speech12.
Full textKavale, Mahendra S., V. G. Parale, A. Venkateswara Rao, P. B. Wagh, and Satish C. Gupta. "Synthesis and physico-chemical properties of organic aerogels." In PROCEEDING OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN APPLIED PHYSICS AND MATERIAL SCIENCE: RAM 2013. AIP, 2013. http://dx.doi.org/10.1063/1.4810503.
Full textCampo, Vanessa Leiria, Ivone Carvalho, and Marcelo Dias Baruffi. "Chemical synthesis of glycopeptide related to T. cruzi and cancer mucins." In 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0113-1.
Full textLarghi, Enrique L., María A. Operto, Andrea V. Coscia, René Torres, and Teodoro S. Kaufman. "Chemical Modifications on Filifolinol. New Derivatives Potentially Suitable for Oral Administration." In 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0386-2.
Full textManna, Liberato. "Halide Perovskite Nanocrystals: Their Synthesis, Chemical, Structural, and Surface Transformations." In 11th International Conference on Hybrid and Organic Photovoltaics. València: Fundació Scito, 2019. http://dx.doi.org/10.29363/nanoge.hopv.2019.055.
Full textIto, Felícia Megumi, Suély Copini, Nathália Rodrigues de Almeida, Kelly Karoliny Lima Pedroni, Ana Camila Micheletti, and Adilson Beatriz. "Determination of the absolute configuration of 6 -Hydroxitricyclo[ 6.2.1.02,7]undeca-9-ene-3-one by chemical correlation." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013911212616.
Full textGorincioi, Elena, Anastasia Verdes, and Fliur Makaev. "Fine organic synthesis approaches for obtaining monastrol by green chemical metodologies." In Ecological chemistry ensures a healthy environment. Institute of Chemistry, Republic of Moldova, 2022. http://dx.doi.org/10.19261/enece.2022.ab24.
Full textTadjarodi, Azadeh, Mina Imani, and Amir hossein Cheshmekhavar. "Synthesis and Characterization of AgInS2 nanoparticles by microwave assisted chemical precipitation." In The 15th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2011. http://dx.doi.org/10.3390/ecsoc-15-00793.
Full textRahimi, Rahmatollah, Rouholah Zare-Dorabei, Asgar Koohi, and Solmaz Zargari. "Synthesis of Porphyrin- Graphene Oxide Nanocomposite for an Optical Chemical Sensor Application." In The 18th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2014. http://dx.doi.org/10.3390/ecsoc-18-a017.
Full textRahimi, Rahmatollah, Rouholah Zare-Dorabei, Asgar Koohi, and Solmaz Zargari. "Synthesis of Porphyrin- Graphene Oxide Nanocomposite for an Optical Chemical Sensor Application." In The 18th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2014. http://dx.doi.org/10.3390/ecsoc-18-a031.
Full textReports on the topic "030503 Organic Chemical Synthesis"
Barnes, Eftihia, Jennifer Jefcoat, Erik Alberts, Hannah Peel, L. Mimum, J, Buchanan, Xin Guan, et al. Synthesis and characterization of biological nanomaterial/poly(vinylidene fluoride) composites. Engineer Research and Development Center (U.S.), September 2021. http://dx.doi.org/10.21079/11681/42132.
Full text