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1
Zhu, Yanlei. „The structural and functional role of whirlin in inner ear hair cells during development“. Electronic Thesis or Diss., Sorbonne université, 2020. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2020SORUS358.pdf.
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Le syndrome d'Usher est l'un des syndromes neurosensoriels génétiques les plus courants, affectant à la fois la vision et l'audition. A ce jour, neuf gènes portant des mutations sont liés à ce syndrome. Mon projet de thèse porte sur la protéine Usher appelée Whirline, une protéine à domaine PDZ cruciale dans les systèmes auditifs et visuels. Nous avons caractérisé la fonction du troisième domaine PDZ, exposé à l'extrémité C-terminale de la protéine. Le PDZ3 reconnaît au moins sept protéines portant des motifs PBM (PDZ Binding Motif): CASK, MPP1, Myosine 15a, Protocadhérine 15 CD3, Cadhérine 23, Harmonine a1 et Taperine. Nous avons résolu les structures à haute résolution de quatre d'entre elles et mis en évidence la capacité de liaison très variée du PDZ3 de la Whirline à divers partenaires des cellules ciliées cochléaires. Du côté N-terminal de la Whirline, le premier domaine PDZ1 reconnait à la fois des motifs peptidiques et des lipides. Nous avons caractérisé en détail ce PDZ1, isolé et inclus dans des constructions multi-domaines, en interaction avec des protéines et des membranes lipidiques par diverses approches biophysiques. La structure de PDZ1 en complexe avec des PBM partenaires et avec des lipides a été résolu, mettant en évidence les résidus impliqués dans de telles interactions. De plus, nous avons documenté le rôle du domaine HHD1 situé juste en amont du domaine PDZ1 et impliqué dans l'auto-association de la Whirline. L’ensemble de ces propriétés de la Whirline est lié à sa fonction de protéine d'échafaudage qui assure l'ancrage des protéines membranaires Usher, un réseau de protéines sous-membranaires essentielles au développement des cellules ciliéesUsher syndrome is one of the most common genetic neurosensory syndromes, which affects both vision and hearing. So far, nine genes’ mutations have been found related to the Usher syndrome. My PhD project focuses on one Usher protein Whirlin, a PDZ containing multi-domain scaffolding protein. We characterised the function of the third PDZ domain which is fully exposed at the C-terminus of the protein. PDZ3 recognizes at least seven proteins PBM (PDZ Binding Motif): CASK, MPP1, Myosin 15a, Protocadherin 15 CD3, Cadherin 23, Harmonin a1 and Taperin, and we solved the high-resolution structures of four of them. We highlighted the unexpected binding capacity of the Whirlin PDZ3. The first N-terminal PDZ1 is a domain of dual functions, which recognizes both protein PBM and lipids. We deeply characterised the PDZ1 in interaction with proteins and lipid membranes by various biophysical approaches. We solved the structures of PDZ1 in complex with partner PBM and with lipid, and highlighted the residues specifically involved in such interactions. In addition, we emphasized the role of the upstream N-terminal HHD1 domain adjacent to the PDZ1 domain and involved in the self-association of Whirlin. Altogether, these properties of Whirlin are related to its function as a scaffolding protein that ensures the anchoring of the membrane Usher proteins, a submembrane protein network essential for the development of hair bundle and for the photoreceptor functioning
2
Delhommel, Florent. „Etude structurale de la Whirline, protéine modulaire cruciale dans les mécanismes de la vision et de l'audition“. Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066151/document.
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La vue et l'ouïe font intervenir des cellules capables de rapidement traduire une onde, lumineuse ou sonore, en un message électrochimique transmissible au cerveau. La fonction de ces cellules sensitives repose sur leurs morphologies uniques. Les mutations de onze gènes sont la cause des syndromes Usher, associant cécité et surdité. Les protéines Usher sont indispensables à l'architecture de ces deux types cellulaires ; elles forment des complexes dont les interactions clés sont maintenues principalement par des domaines PDZ. L'une des protéines centrales de ce réseau est la Whirline, une protéine multi-domaine contenant trois domaines PDZ. Pour comprendre les bases moléculaires des syndromes Usher, nous nous sommes concentrés sur la caractérisation biochimique et biophysique de la Whirline. Nous avons identifié un nouveau domaine HHD2 de la Whirline dont nous avons obtenue la structure à haute résolution et déterminé le comportement en solution, isolé et avec les domaines adjacents. Nous avons ensuite caractérisé un supramodule transitoire entre deux domaines PDZ, maintenu par des extensions structurées de chacun des domaines. Nous avons résolu la structure de la conformation compacte unique de ce complexe et étudié son équilibre avec un ensemble de conformations étendues. Nous avons enfin caractérisé in vitro le réseau d'interaction des domaines PDZ de la Whirline avec les protéines Usher. L'ensemble de nos résultats sur la structure modulaire et l'interactome de la Whirline permet de mieux comprendre le rôle de la Whirline dans les différents complexes Usher et d'expliquer les conséquences de ses mutations sur les mécanismes moléculaires de l'audition et de la visionVision and hearing rely on the capacity of cells to rapidly transduce electromagnetic waves or sound waves into chemical messages that are transmissible to the brain. The function of these sensory cells requires unique morphologies. The mutations of eleven genes are responsible for Usher syndromes, associating blindness and deafness. The Usher proteins are pivotal to the architecture of the photoreceptor and hearing cells. They form complexes in which the critical interactions are mainly maintained by PDZ domains. One of these central proteins is Whirlin, a multi-domain protein encompassing three PDZ domains. To understand the molecular basis of the Usher syndromes, we focused our project on the biochemical and biophysical characterization of Whirlin. We identified a new HHD2 domain on Whirlin, for which we solved the structure at high resolution and determined the behavior in solution, isolated or with adjacent domains. We then identified a transient supramodule between two PDZ domains, maintained by PDZ structured extensions. We determined the structure of the compact and unique conformation of this tandem and we characterized its equilibrium with an ensemble of more extended conformations. Finally, we characterized in vitro the network of interaction of the PDZ domains of Whirlin, with the majority of the Usher proteins. Our results on the modular structure and the interactome of Whirlin get insight into the role of Whirlin in the numerous complexes formed by the Usher proteins and allow to better explain the consequences of its mutation on the molecular mechanisms of hearing and vision
3
Delhommel, Florent. „Etude structurale de la Whirline, protéine modulaire cruciale dans les mécanismes de la vision et de l'audition“. Electronic Thesis or Diss., Paris 6, 2017. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2017PA066151.pdf.
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La vue et l'ouïe font intervenir des cellules capables de rapidement traduire une onde, lumineuse ou sonore, en un message électrochimique transmissible au cerveau. La fonction de ces cellules sensitives repose sur leurs morphologies uniques. Les mutations de onze gènes sont la cause des syndromes Usher, associant cécité et surdité. Les protéines Usher sont indispensables à l'architecture de ces deux types cellulaires ; elles forment des complexes dont les interactions clés sont maintenues principalement par des domaines PDZ. L'une des protéines centrales de ce réseau est la Whirline, une protéine multi-domaine contenant trois domaines PDZ. Pour comprendre les bases moléculaires des syndromes Usher, nous nous sommes concentrés sur la caractérisation biochimique et biophysique de la Whirline. Nous avons identifié un nouveau domaine HHD2 de la Whirline dont nous avons obtenue la structure à haute résolution et déterminé le comportement en solution, isolé et avec les domaines adjacents. Nous avons ensuite caractérisé un supramodule transitoire entre deux domaines PDZ, maintenu par des extensions structurées de chacun des domaines. Nous avons résolu la structure de la conformation compacte unique de ce complexe et étudié son équilibre avec un ensemble de conformations étendues. Nous avons enfin caractérisé in vitro le réseau d'interaction des domaines PDZ de la Whirline avec les protéines Usher. L'ensemble de nos résultats sur la structure modulaire et l'interactome de la Whirline permet de mieux comprendre le rôle de la Whirline dans les différents complexes Usher et d'expliquer les conséquences de ses mutations sur les mécanismes moléculaires de l'audition et de la visionVision and hearing rely on the capacity of cells to rapidly transduce electromagnetic waves or sound waves into chemical messages that are transmissible to the brain. The function of these sensory cells requires unique morphologies. The mutations of eleven genes are responsible for Usher syndromes, associating blindness and deafness. The Usher proteins are pivotal to the architecture of the photoreceptor and hearing cells. They form complexes in which the critical interactions are mainly maintained by PDZ domains. One of these central proteins is Whirlin, a multi-domain protein encompassing three PDZ domains. To understand the molecular basis of the Usher syndromes, we focused our project on the biochemical and biophysical characterization of Whirlin. We identified a new HHD2 domain on Whirlin, for which we solved the structure at high resolution and determined the behavior in solution, isolated or with adjacent domains. We then identified a transient supramodule between two PDZ domains, maintained by PDZ structured extensions. We determined the structure of the compact and unique conformation of this tandem and we characterized its equilibrium with an ensemble of more extended conformations. Finally, we characterized in vitro the network of interaction of the PDZ domains of Whirlin, with the majority of the Usher proteins. Our results on the modular structure and the interactome of Whirlin get insight into the role of Whirlin in the numerous complexes formed by the Usher proteins and allow to better explain the consequences of its mutation on the molecular mechanisms of hearing and vision
4
Gates, Kiza Kristine. „Myxospore detection in soil and angler movement in Southwestern Montana implications for whirling disease transport /“. Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/gates/GatesK0507.pdf.
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KHATOON, RABEYA. „Whirling Hybrids: A Dichotomy Of Belonging“. VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5892.
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Migration is a phenomenon wherein individuals relocate from one country to another, albeit temporarily or permanently, for numerous reasons. The State of Qatar is a highly diverse nation with a large population of foreign residents. According to Priya D’Souza, as of 2017, 60 percent of the resident population in Qatar are from South Asia. Growing up in this environment, third culture kids develop a unique, hybrid culture through experiencing multiple cultures. This research investigates a dichotomy of belonging from the perspective of South Asians in Qatar. A series of hybridized spinning tops were produced in collaboration with a South Asian artisan. These hybridized artifacts are infused with sensory materials in order to elicit an emotive response, engage memory, and celebrate the merging of diverse cultures.
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Hamilton, Andrew John. „The aetiology of whirling disease, Myxosoma cerebralis“. Thesis, Imperial College London, 1987. http://hdl.handle.net/10044/1/38344.
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Marsden, James Anthony. „Experimental and numerical studies of whirling fires“. Thesis, University of Central Lancashire, 2005. http://clok.uclan.ac.uk/8689/.
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Motivation of this study stems from the need to understand the physical mechanisms of whirling fires that occur in an open space and within enclosures. Buoyant whirling flames may be potentially more destructive than ordinary fires due to greater burning rate, higher concentration of heat release in a small region of the plume core, increased radiative output and unexpected smoke movement. The effects of rotation upon the structure and behaviour of buoyant flames have not yet been thoroughly studied and understood. Investigation of this phenomenon is therefore required to allow techniques to be developed that will counter the threat of such outbreaks. Also, the mechanisms controlling the development and stability of whirling flames are of fundamental interest for refined modelling of coherent and self-organised flame behaviour. This work, is an experimental, theoretical and numerical study of whirling fires. Experimental results, a modified CFD model and simulations of whirling flames are presented within this Thesis. The work aims to overcome the limitations of the previous research of whirling fires which is insufficient from both an experimental and theoretical point of view. Firstly, experimental studies of intermediate (room-size) scale whirling fires have not yet been comprehensively reported, despite a great deal of attention devoted to both large scale mass fires and smaller laboratory flames. Experimental studies undertaken using a facility at the Greater Manchester Fire and Rescue Service Training Centre fill this gap, thus demonstrating that whirling flames may develop within a compartment. The periodic precession, formation and destruction of the whirling flame and the increase of the time-averaged burning rate (compared to non-whirling flames in the open space) have been observed. Three fuels with significantly different burning rates (diesel, heptane and ethanol) were investigated in this work. Secondly, previously published results of theoretical analysis of rotating flames were oversimplified and based on strict limitations of the integral model or the inviscid flow assumption. Also there have only been few attempts to undertake CFD modelling of whirling flames. In published studies, radiative heat transfer was not modelled and the burning rate was not coupled with the incident heat flux at the fuel surface. To overcome these limitations, the CFD fire model Fire3D, developed in the Centre for Research in Fire and Explosion Studies, has been adapted to allow numerical simulations of rotating buoyant turbulent diffusion flames. The turbulence model was modified to take into account stabilisation of turbulent fluctuations due to the centrifugal acceleration within the rotating flow. Theoretical analysis of the vorticity equation revealed the physical mechanisms responsible for vorticity concentration and amplification in the rising plume affected by externally imposed circulation. This explains the significant flame elongation (when compared to non-rotating cases) observed in the experiments. Computational results have also been compared to video-recordings of the experimental flames produced; flame elongation was replicated and similar stages of oscillating flame evolution, including formation and destruction of the vortex core, have been identified. Implications of the phenomena studied in relation to fire engineering are also provided. This study contributes to a performance based framework for an engineering approach, which is reliant upon detailed quantitative analysis and modelling. Such an approach is encouraged by modem fire safety legislation including the guides to fire safety engineering BS9999-21 and BS79742 'British Standard 9999-2 Draft Code of Practice for fire safety in the design, construction and use of buildings. BSI, 2004. UK. 2 British Standard BS7974 Application of fire safety engineering principles to the design of buildings. BSI, 2001-2003. UK.
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Suryanarayanan, Arun. „Experimental measurement and analysis of wall pressure distribution for a 50% eccentric whirling annular seal“. Texas A&M University, 2003. http://hdl.handle.net/1969.1/1205.
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In any rotating machinery, the geometry of the seal influences the extent of systemleakage. The path taken by the flow in the clearance volume is dependent on the seal and rotor profile. The clearance between a new "seal-rotor" combination is uniform except for small variations during manufacturing and assembly. With time this annular cross section undergoes further physical changes causing non-uniform flow in the annular volume. This azimuthally varying leakage through the seal-rotor annulus creates unbalanced forces on the rotor causing it to whirl. It is essential to identify the reasons for these unwanted forces. Velocity profiling of the clearance volume flow was performed by Morrison et al. (1992) using 3-D LDA measurements on annular and labyrinth seals operating with 50% dynamic eccentricities and a whirl ratio of one. However, this alone does not provide a complete matrix of data for the conditions prevailing in the clearance zone. Additional information of mean and instantaneous wall pressure distributions for 0%, 10%, 25% and 50% rotor dynamic eccentricity for whirl ratios of zero and one, with positive pre-swirl, no pre-swirl and negative pre-swirl conditions were measured by Robic (1999). The data collected showed that the pressure field on the seal walls reversed itself between the whirling and non-whirling conditions. As a continuance of the earlier works, the present effort investigates the effect of whirl ratio variation for a 50% eccentric smooth annular seal at a leakage Reynolds number of 24000. An attempt has been made to collect pressure data for negative whirl ratios also under similar test conditions.
A seal test rig capable of handling different eccentricities and whirl ratios simultaneously was designed and constructed for this purpose. Mean and instantaneous wall pressure data were recorded for 50% eccentricity with whirl ratios between ? 1 for a rotor speed of 1800. For a rotor speed of 2700, whirl ratios tested were between ? 0.6 and for 3600 rotor speed, whirl ratios ranging between ? 0.5 were tested. From the collected data a detailed analysis of wall pressures along the seal surface is performed following the technique described by Winslow (1994) and Robic (1999).
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Shum, Wai Sun. „Vibration frequencies of whirling rods and rotating annuli“. Thesis, Curtin University, 2005. http://hdl.handle.net/20.500.11937/1404.
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Static Whirling Rods: Past researchers suggested that “static instabilities” exist at certain rotational speeds of whirling rods. This thesis shows these instabilities are an artefact of the material constitutive laws that are being used well outside their range of applicability. An alternative approach is developed where strains due to rotation are separated from the superimposed vibration. This enables the generally predicted lowering of longitudinal natural frequencies with rotational speed shown to be simply a result of the bulk changes in the geometry of whirling rods. Steady state equations of whirling rods are formulated in Lagrangian coordinates. Due to the non-linear nature of the governing equations, an original numerical method is applied to solve the problem. Numerical results are compared with analytical results obtained from the linearized uniaxial model. There is a close agreement between these two models at low angular velocities. However, at high angular velocities, discrepancies between them arise, confirming that the nonlinear strain-displacement relationship has significant effect on the results and the inferred “static instabilities”. This approach first solves the “static” problem of the deformed geometry of a highly strained whirling rod before longitudinal natural modes are determined by classical methods. Furthermore, conditions for existence and uniqueness of solutions are derived. Dynamic Rotating Annuli: In-plane modes of vibration of annular plates are investigated. Two different models of equations one from Bhuta and Jones and the other from Biezeno and Grammel that govern the rotational motions of annuli will be studied. Since Biezeno and Grammel’s model was originally derived in Eulrian coordinates, their model will be transformed to the Lagrangian coordinates for the purpose of comparison with Bhuta and Jones’ model.The solutions of the equations assume small oscillations of vibration being superimposed on the steady state of the annulus while it is in rotation. Exact and approximate solutions are obtained for the Bhuta and Jones’ model, where the approximate solutions on in-plane displacements and natural frequencies are acquired by ignoring the Coriolis effect. A proposed numerical scheme is implemented to solve the governing equations coupled with radial and circumferential displacements. Uniqueness of solutions will be mentioned although it will not be rigorously derived because it is out of the scope of this thesis. Approximate analytical results show that both radial and circumferential natural frequencies are decreasing when the rotational speed of an annulus is increasing. The exact and numerical results on both models that take the Coriolis effect into account show that radial natural frequencies are increasing and circumferential natural frequencies are decreasing when the rotational speed of an annulus is increasing.
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Shum, Wai Sun. „Vibration frequencies of whirling rods and rotating annuli“. Curtin University of Technology, Faculty of Engineering and Computing, 2005. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=16363.
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Static Whirling Rods: Past researchers suggested that “static instabilities” exist at certain rotational speeds of whirling rods. This thesis shows these instabilities are an artefact of the material constitutive laws that are being used well outside their range of applicability. An alternative approach is developed where strains due to rotation are separated from the superimposed vibration. This enables the generally predicted lowering of longitudinal natural frequencies with rotational speed shown to be simply a result of the bulk changes in the geometry of whirling rods. Steady state equations of whirling rods are formulated in Lagrangian coordinates. Due to the non-linear nature of the governing equations, an original numerical method is applied to solve the problem. Numerical results are compared with analytical results obtained from the linearized uniaxial model. There is a close agreement between these two models at low angular velocities. However, at high angular velocities, discrepancies between them arise, confirming that the nonlinear strain-displacement relationship has significant effect on the results and the inferred “static instabilities”. This approach first solves the “static” problem of the deformed geometry of a highly strained whirling rod before longitudinal natural modes are determined by classical methods. Furthermore, conditions for existence and uniqueness of solutions are derived. Dynamic Rotating Annuli: In-plane modes of vibration of annular plates are investigated. Two different models of equations one from Bhuta and Jones and the other from Biezeno and Grammel that govern the rotational motions of annuli will be studied. Since Biezeno and Grammel’s model was originally derived in Eulrian coordinates, their model will be transformed to the Lagrangian coordinates for the purpose of comparison with Bhuta and Jones’ model.The solutions of the equations assume small oscillations of vibration being superimposed on the steady state of the annulus while it is in rotation. Exact and approximate solutions are obtained for the Bhuta and Jones’ model, where the approximate solutions on in-plane displacements and natural frequencies are acquired by ignoring the Coriolis effect. A proposed numerical scheme is implemented to solve the governing equations coupled with radial and circumferential displacements. Uniqueness of solutions will be mentioned although it will not be rigorously derived because it is out of the scope of this thesis. Approximate analytical results show that both radial and circumferential natural frequencies are decreasing when the rotational speed of an annulus is increasing. The exact and numerical results on both models that take the Coriolis effect into account show that radial natural frequencies are increasing and circumferential natural frequencies are decreasing when the rotational speed of an annulus is increasing.
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Lukins, Halcyon Josephine. „Dynamics of the waterborne stage of Myxobolus cerebralis estimated directly by packed-bed filtration“. Thesis, Montana State University, 2004. http://etd.lib.montana.edu/etd/2004/lukins/LukinsH0805.pdf.
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McGinnis, Stephanie Ann. „An analysis of whirling disease risk in Western Montana“. Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/mcginnis/McGinnisS0507.pdf.
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Koobak, Redi. „Whirling Stories : Postsocialist Feminist Imaginaries and the Visual Arts“. Doctoral thesis, Linköpings universitet, Tema Genus, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-90902.
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This thesis is about the geopolitics of feminist knowledge and the role of the visual arts in conceiving and reconfiguring postsocialist feminist imaginaries. Its central concern is to contest the fantasy, prevalent within Western feminist theorizing, of a “lag” between Western and former Eastern Europe. The thesis explores these imaginaries on a micro scale, zooming in on the deeply personal and political artwork of a contemporary feminist and lesbian-identified Estonian artist, Anna-Stina Treumund. This partial and limited focus on Treumund’s photographic self-portraiture enables us to look into the intensities and specificities of individual experience in postsocialist space. Throughout, the thesis evokes a whirling subject as a feminist figuration. This is simultaneously a reference to the embodied and the relational structure of knowledge-systems and world-making. Drawing on postsocialist, postcolonial, queer and feminist visual culture studies, the author argues that Treumund’s art is always already embedded in the local context, as it builds on and problematizes the existing discussions of feminist generations, theorizing, activism and art practices. Combining close readings of Treumund’s artworks with contemporary theoretical debates in feminist studies, encounters with the artist and autobiographical narratives, this thesis asserts: there is no “lag”. More importantly, it is of utmost ethical and political importance to pay closer attention to geopolitical locatedness as an axis of difference that matters in contemporary feminist theorizing.Den här doktorsavhandlingen handlar om geopolitik i feministisk kunskap och bildkonstens roll i förståelse och omskapande av postsocialistiska feministiska föreställningar. Dess huvudsakliga fokus handlar om att bestrida den i västerländsk feministisk teori ofta förekommande fantasin om att före detta Östeuropa på olika sätt ”släpar efter” i relation till väst. Doktorsavhandlingen utforskar dessa föreställningar på mikronivå då den zoomar in på det djupt personliga och politiska bildkonstarbete utfört av den samtida feministiska och självidentifierat lesbiska estniska konstnärinnan Anna-Stina Treumund. Avhandlingens partiella fokus på Treumunds fotografier i form av självporträtt möjliggör för oss att få inblick i de intensiteter och specifika förhållanden som utgör en individuell erfarenhet av att befinna sig i det postsocialistiska rummet. Genomgående i doktorsavhandlingen används det virvlande subjektet som feministisk figuration. Figurationen innebär simultant en referens till den förkroppsligade och den relationella aspekten av kunskapssystem och skapande av världen. Med utgångspunkt i postsocialistiska, postkoloniala, queera och feministiska studier av visuell kultur argumenterar författaren att Treumunds bildkonst alltid redan är inbäddad i en lokal kontext, detta sedan den växer fram ur och problematiserar de diskussioner som pågår mellan feministiska generationer, i teori, aktivism och bland konstutövare. Genom att kombinera närläsning av Treumunds konstnärliga arbete med samtida teoretisk debatt inom feministiska studier, med möten med konstnärinnan, och med självbiografiska berättelser, försäkrar denna avhandling: det finns ingen “eftersläpning”. Än mer väsentligt är att betona att det är av yttersta etisk och politisk vikt att ägna mer uppmärksamhet åt geopolitiska lokaliseringar som skillnadsskapande faktor i samtida feministisk teoribildning.
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Mulkens, M. J. M. „Measurement of aerodynamic stability derivatives using a whirling arm facility“. Thesis, Cranfield University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359563.
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Dassanayake, Achala Viomy. „Machining dynamics and stability analysis in longitudinal turning involving workpiece whirling“. Thesis, [College Station, Tex. : Texas A&M University, 2006. http://hdl.handle.net/1969.1/ETD-TAMU-1817.
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Hyde, Griffin Nicholas. „Investigation into the Local and Global Bifurcations of the Whirling Planar Pendulum“. Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/91395.
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This thesis details the investigation into the Whirling Planar Pendulum system. The WPP is a pendulum that is spun around a vertical spin axis at a controllable horizontal offset. This dynamical system exhibits both local and global bifurcations. The local pitchfork bifurcation leads to the splitting of a single stable equilibrium point into three (two stable and one unstable), as the spin rate is increased. The global bifurcations lead to two independent types of chaotic oscillations which are induced by sinusoidal excitations. The types of chaos are each associated with one of two homoclinic orbits in the system's phase portraits. The onset of each type of chaos is investigated through Melnikov's Method applied to the system's Hamiltonian, to find parameters at which the stable and unstable manifolds intersect transversely, indicating the onset of chaotic motion. These results are compared to simulation results, which suggest chaotic motion through the appearance of strange attractors in the Poincaré maps. Additionally, evidence of the WPP system experiencing both types of chaos simultaneously was found, resulting in a merger of two distinct types of strange attractor.Master of Science
This report details the investigation into the Whirling Planar Pendulum system. The WPP is a pendulum that is spun around a vertical spin axis at a controllable horizontal offset. This system can be used to investigate what are known as local and global bifurcations. A local bifurcation occurs when the single equilibrium state (corresponding to the pendulum hanging straight down) when spun at low speeds, bifurcates into three equilibria when the spin rate is increased beyond a certain value. The global bifurcations occur when the system experiences sinusoidal forcing near certain equilibrium conditions. The resulting chaotic oscillations are investigated using Melnikov’s method, which determines when the sinusoidal forcing results in chaotic motion. This chaotic motion comes in two types, which cause the system to behave in different ways. Melnikov’s method, and results from a simulation were used to determine the parameter values in which the pendulum experiences each type of chaos. It was seen that at certain parameter values, the WPP experiences both types of chaos, supporting the observation that these types of chaos are not necessarily independent of each other, but can merge and interact.
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Jery, Belgacem Brennen Christopher E. Brennen Christopher E. Acosta Allan J. Caughey Thomas Kirk. „Experimental study of unsteady hydrodynamic force matrices on whirling centrifugal pump impellers /“. Diss., Pasadena, Calif. : California Institute of Technology, 1987. http://resolver.caltech.edu/CaltechETD:etd-03262007-130547.
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Murcia, Silvia. „Myxobolus cerebralis in native Cutthroat trout of three spawning tributaries to Yellowstone Lake a qualitative ecological risk assessment /“. Thesis, Montana State University, 2008. http://etd.lib.montana.edu/etd/2008/murcia/MurciaS0808.pdf.
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Most environments impose periodic or stochastic stress on natural populations, which increase susceptibility to diseases. Infection by Myxobolus cerebralis (exotic parasite causing salmonid whirling disease) is strongly influenced by a stream\'s physicochemical attributes and stressors, which may also affect host pathology. Susceptibility to M. cerebralis varies greatly among different species and subspecies of the salmonid host, but little is known about lesion severity or location of infection among the native Yellowstone cutthroat trout (Oncorhynchus clarki bouvieri). In 2002 and 2003 we performed a series of 10-day sentinel cutthroat fry exposures and habitat assessments in various sites of three M. cerebralis-positive tributaries to Yellowstone Lake: the Yellowstone River, Pelican Creek, and Clear Creek. At 90 and 150 days post-exposure, fry were examined by polymerase chain reaction and histology to determine prevalence, severity, and location of infection. The goal was to identify spatiotemporal patterns of infection, and physicochemical features of the streams influencing it, and potentially facilitating parasite invasion and establishment. Results on fish (young and adult) host infection data, environmental attributes, and tubificid host presence/absence data in the study streams were used to develop an ecological risk assessment for parasite establishment and whirling disease in this ecosystem. Results from our qualitative risk ranking systems suggest that the cutthroat trout of the Yellowstone Lake basin are highly susceptible to M. cerebralis infection, with the most severe lesions in cartilage of the cranium and jaws, especially in systems with high water temperatures and ionic content. Our results also suggest that such environmental features are most conducive to parasite establishment, especially in tributaries of the lake basin used by cutthroat trout as spawning and rearing habitats. Thus, this study has implications for both ecology and parasitology as it reveals that environmental components can affect when and where a pathogen resides within the host, and thereby affect manifestation of disease. Recognition of the specific environmental attributes most conducive to parasite establishment, and disease, can increase future diagnostics, detection, and management efforts, strengthening the likelihood of correctly predicting M. cerebralis\' and similar pathogenic invasions and establishment in unsampled sites.
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Smith, Rob. „Whirl for wind ensemble /“. Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.
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Varela, Mosquera Anabel. „The positional cloning of the mouse deafness gene whirler“. Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270783.
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Cusano, Domenic. „Experimental measurement of phase averaged wall-pressure distributions for a 25% eccentric whirling annular seal“. Thesis, Texas A&M University, 2003. http://hdl.handle.net/1969.1/3955.
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Instantaneous wall-pressure data were recorded for a 25% eccentric whirling annular seal for rotor speeds of 1800RPM and 3600RPM, axial Reynolds numbers of 24000 and 12000, and whirl ratios of 0.1-1.0 following the procedure set forth by Winslow (1994), Robic (1999) and Suryanarayanan (2003). Overall, the phase averaged wall-pressure distributions were consistent with previous results. The Âswitch in the pressure distribution measured by Suryanarayanan (2003) and Robic (1999) from pressure to suction between the seal entrance and exit occurs at and above a whirl ratio of 0.7 for 1800RPM and 0.4 for 3600RPM. For both rotor speeds, decreasing the flow rate by one-half also decreases the wall pressure fluctuation distributions by one-half. For whirl ratios less than 0.5, the phase averaged pressure field was relatively constant which leads to minimal forces being imparted on the rotor by the fluid in the annulus. Talyor-Gortler vortices are measured for 1800RPM and Re=24000 at whirl ratios 0.1 and 0.3-0.7. As the whirl ratio increases past 0.5, longitudinal vortices begin to emerge in the pressure contours and skew axially with 180° shifts occurring when the Taylor-Reynolds ratio is large enough. Longitudinal vortices were measured for both rotor speeds when the whirling motion is greater than 1400RPM for Re=12000 and greater than 1600RPM for Re=24000. Attempts were made to apply Childs (1983) procedure for finding the rotordynamic coefficients of annular seals; however, the seal moves in a non-circular orbit about the sealÂs center so Childs analysis cannot be applied.
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Thompson, Elizabeth Danielle. „Study of Forces and Dynamic Coefficients in Whirling and Eccentric Labyrinth Seals Using ANSYS-CFX“. Thesis, Virginia Tech, 2009. http://hdl.handle.net/10919/32328.
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Labyrinth seal force estimates are important to the prediction of the stability of turbomachinery. The force prediction methods fall into several categories: experiments, bulk flow analysis, and finite volume analysis. Finite volume analysis can be split into two subcategories: self-developed and commercial.
In this research, a commercial computational fluid dynamics (CFD) program called ANSYS-CFX was used to predict the forces generated in a labyrinth seal whirling at specified speeds. The results were compared to data from VT-FAST, a bulk flow code, and TASCflow, another commercial CFD program. It was shown that there were discrepancies among the results, and several hypotheses were made as to the reason for these discrepancies.
Additionally, ANSYS-CFX was used to study the effect of labyrinth seal eccentricity ratio on the resultant force generated. It was shown that the radial force component within the seal behaved linearly with respect to eccentricity ratio. However, the tangential force component had no distinguishable relationship with the eccentricity ratio. It was hypothesized that the lack of a relationship was caused by the small fluctuations in the inlet swirl. Although the inlet swirl varied very little at each eccentricity ratio, it was shown there was a relationship between the tangential force and inlet swirl.Master of Science
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Isemer, Rena [Verfasser]. „Die WHIRLY-Proteine von Arabidopsis thaliana / Rena Isemer“. Kiel : Universitätsbibliothek Kiel, 2013. http://d-nb.info/1043957642/34.
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Butler, Diana Hochstedt. „Standing against the whirlwind : evangelical Episcopalians in nineteenth-century America /“. New York : Oxford university press, 1995. http://catalogue.bnf.fr/ark:/12148/cb37720458c.
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Varley, David Hugh. „The whirling wheel : the male construction of empowered female identities in Old Norse myth and legend“. Thesis, Durham University, 2015. http://etheses.dur.ac.uk/11057/.
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This thesis examines the body of medieval literature associated with Old Norse myth and legend. Though this is a diffuse corpus produced over a long span of time and from a wide geographical area, it is possible to establish connections between texts and to highlight certain recurring narrative patterns that are deeply entrenched in this literary tradition. The specific focus of the present study is to analyse the narrative patterns that characterise the interactions between male and female figures. It has long been understood that female figures tend to occupy carefully defined social roles in this body of literature, and much work has been done in assessing these. This thesis takes the unique approach of investigating whether these roles can be viewed, not as a product of the mentality of the writers of this literary material, but rather as a product of male characters within the literary narratives themselves. The investigation poses the question of whether men can be seen, through their words, thoughts, and actions, to be responsible for creating female identities. Intimately connected to the concept of identity creation is the idea of power: this thesis will argue that most male attempts to redefine female identity is motivated by a desire to acquire, control, negate, or otherwise alter, the powers possessed by females. Quite often, because fallible males demonstrate an imperfect understanding of female power, there can be a marked disparity between the abilities certain women are thought to possess, and those they actually do. The thesis will examine a large selection of supernatural female figures, across a broad range of literature, ultimately to suggest that the male creation of female power is deeply entrenched in narrative patterns observable in many different contexts.
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Resende, Hugo Borelli. „Estudos na análise de whirl flutter“. Instituto Tecnológico de Aeronáutica, 1987. http://www.bd.bibl.ita.br/tde_busca/arquivo.php?codArquivo=1536.
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O whirl flutter, em se tratando de uma instabilidade que pode ocorrer durante o vôo de uma aeronave e levar a uma condição de falha estrutural, deve ser devidamente estudado durante o projeto de uma aeronave moderna de modo a manter manter um nível de segurança adequada, mesmo porque o processo de homologação final inclui requesitos sobre a ocorrência do fenômeno. Assim, para uma empresa aeronáutica é essencial que exista um programa numérico acessível que permita este tipo de análise para o caso de configurações as mais gerais possíveis. Este estudo visou exatamente a implementação de um programa assim, tendo sido utilizado um modelo em que o motor é considerado um corpo rígido apoiado elasticamente em uma estrutura de suporte, a qual não necessariamente é rígida. A extensão para mais de um corpo é imediata, considerando-se, então, que os corpos estão ligados elasticamente entre si. Todos os seis graus de liberdade dos centros de gravidade de cada corpo são mantidos. Com relação aos esforços aerodinâmicos, são utilizados resultados convencionais para hélices de pás rígidas, mas procurou-se mostrar um caminho através do qual fosse possível a utilização de uma teoria de superfície de sustentação para o cálculo aerodinâmico. Finalizando, foram feitas comparações com resultados anteriores, além de se procurar verificar as diferenças de comportamento das fronteiras de estabilidade entre os modelos com graus de complexidade distintos, especialmente entre modelos de dois e seis graus de liberdade.
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Franz, Ronald John Acosta Allan J. „Experimental investigation of the effect of cavitation on the rotordynamic forces on a whirling centrifugal pump impeller /“. Diss., Pasadena, Calif. : California Institute of Technology, 1989. http://resolver.caltech.edu/CaltechETD:etd-02022007-133417.
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Davidson, Paul Scott. „Capturing the whirlwind : Paris depicted through the medium of Revolutionary Prints“. Thesis, Queen Mary, University of London, 2013. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8474.
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This thesis is the product of an Arts and Humanities Research Council Collaborative Doctoral Award, the result of which was the production of a catalogue of the Tableaux de la Révolution. Made up of some 500 prints, presented in four nineteenth century bound volumes, the Tableaux de la Révolution is part of the Rothschild Collection held at Waddesdon Manor, Buckinghamshire. One of the key goals of the project was to create an online resource that is now publicly accessible by internet. The initial cataloguing was split between Claire Trévien, also a recipient of and AHRC CDA, which she held in the French Department at the University of Warwick and myself. We ‘tombstone catalogued’ some 250 prints each, analysing the following: date, the identification of printing method and style, identification of subject and theme, a description of the image, translation and description of the text, as well as the construction of a theme-based search engine. My own contribution was the first and fourth of the large volumes in which the prints are kept (accession numbers: 4232.1 and 4222). Additional background research has also been conducted for each print, extended upon in the final in-depth analyses of circa 30 prints on my part. The items which received this treatment under my individual care were acc. nos: 4222.7.4, 4222.9.8, 4222.10.11, 4222.13.16, 4222.14.17, 4222.21.27, 4222.35.44, 4222.47.61, 4232.1.13.27, 4232.1.19.40, 4232.1.23.46, 4232.1.42.83, 4232.1.43.85, 4232.1.43.86, 4232.1.46.92, 4232.1.48.96, 4232.1.52.104, 4232.1.52.107, 4232.1.57.113, 4232.1.69.142, 4232.1.70.144, 4232.1.80.164, 4232.1.83.170, 4232.1.84.171, 4232.2.24.38, 4232.2.31.50, 4232.2.31.51, 4232.2.35.61 and 4232.2.47.80 (http://www.waddesdon.org.uk/collection/special-projects/tableaux-paul). The work done at Waddesdon Manor also proved invaluable vis-à-vis my thesis. The study of the prints laid the groundwork for me to broaden my knowledge of prints as a visual medium. In addition to this, an exhibition of the Tableaux de la Révolution was held at Waddesdon Manor in summer 2011. Part of the impact of the final catalogue also included a public lecture and ‘hands-on’ session, which I co-hosted with Claire Trévien. The catalogue of the Tableaux de la Révolution may be consulted on the Waddesdon website at: http://waddesdon.org.uk/collection/special-projects/tableau.
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Munro, Andrew Roy. „Identification of life history variation in salmonids using otolith microchemistry and scale patterns implictions for illegal introductions and for whirling disease in Missouri River rainbow trout /“. Connect to this title online Connect to this title online (alternate address), 2004. http://www.montana.edu/etd/available/munro%5F04.html.
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Kamesh, Punithavathy. „Oil-whirl instability in an automotive turbocharger“. Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/188121/.
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This thesis is concerned with a theoretical investigation into the nonlinear dynamic behaviour of a turbocharger. Specifically the instabilities due to oil-whirl are examined. These are self-excited vibrations existing in the form of an in-phase whirl mode and a conical whirl mode. Waterfall plots were provided by Cummins Turbo-Technologies Ltd., Huddersfield, UK, based on test data using two different unbalance levels on a turbocharger. The test with the high unbalance indicated that there was shift in the sub-synchronous frequency to synchronous frequency between about 80,000 rpm to 130,000 rpm. The literature suggests that this self-excited vibration can be suppressed using forced excitation. Moreover, it is well known that the existence of limit cycles enables successful operation of a turbocharger. This limit cycle is a periodic motion attributed to the nonlinearity of the oil-film, other than the stable and the unstable equilibrium states predicted by the linear analysis. Hence, a nonlinear analysis is required to analyse the limit cycle and to determine the effect of synchronous excitation on it. In the literature a variety of parameters has been shown to influence the dynamic behaviour of a rotor-bearing system. To avoid over-complicated mathematical modeling, the influence of two such parameters: gyroscopic moment and shaft flexibility are first investigated in this thesis using linear stability theory to determine their significance. Effects of gyroscopic action are investigated using symmetric and asymmetric rigid rotors supported on short journal bearings with full-film using rigid and damped supports. In this thesis, the damper supported journal bearing is used to simulate the floating ring bearings that are commonly used in automotive turbochargers. The outer film of the floating ring bearing is treated as an external damper, since the ring is assumed not to rotate but only wobble giving the damping effect from the squeezing action. A gyroscopic coefficient, which is defined as the ratio of the polar to the transverse moment of inertia of the rotor, is introduced. The threshold value of this coefficient is determined to be 1 for the suppression of the conical whirl instability. The stability of the in-phase whirl mode is unaffected by this parameter. A flexible rotor mounted in floating ring bearings with full-film, is analysed to confirm that it behaves as a rigid body up to a speed of 100,000 rpm. Prior to the unbalance response study, a perfectly balanced rigid rotor supported by rigidly supported bearings is first analysed to determine the nonlinear behaviour of the in-phase whirl. To include the stiffness-like radial restoring force, an oscillating 2 π -film cavitation model for the hydrodynamic bearings is used. The effect of a static load on the rotor is analysed to determine the nonlinear behaviour for a wide range of steady-state eccentricity ratios. A parameter plane separating the region of instability from that of stability is presented using linear analysis to determine the stability threshold at which the oil-whirl is initiated. The onset of oil-whirl phenomenon is shown to be the Hopf bifurcation. Particular emphasis is placed on examining the limit cycles (periodic oscillations) around the stability threshold. Reducing the nonlinear equation of motion to Poincare normal form, the first Lyapunov coefficients are evaluated to show the change in the type of bifurcation from sub-critical bifurcation (disappearance of an unstable limit cycle) to super-critical bifurcation (appearance of a stable limit cycle) around the stability threshold. Such bifurcations are demonstrated through plots of orbits using numerical integration by the Runge-Kutta method. With some unbalance added to the rotor-system, waterfall plots are generated to simulate the response characteristics observed in the test data, by running-up the speed. After the Centre Manifold reduction, the equations of motions are averaged for analysis. Using a numerical and an analytical procedure, it is shown that the unbalance is more effective in the transient motion than in the steady-state condition. Unbalance introduces a reduction in the growth rate of whirl amplitude upto a certain optimum unbalance value, above which the effect is reversed. The mechanism behind this behaviour is shown to be the shift in phase caused by the unbalance at the start of whirling, when the dynamic forces are comparable with the unbalance force. This is due to the coupling effect of amplitude and phase in an unbalanced rotor system
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Paige, Adam John William. „Towards positional cloning of a deafness causing mutation in whirler (WI) mice“. Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285835.
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Rogers, Michael John Christopher. „Whirler : the gene and its effect on the function of the ear“. Thesis, Open University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363488.
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Dadalto, Silvana Pinheiro. „Estudo da família de fatores de transcrição Whirly em soja“. Universidade Federal de Viçosa, 2016. http://www.locus.ufv.br/handle/123456789/9365.
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Plantas submetidas a estresse possuem complexos mecanismos de defesa, que resultam na expressão de proteínas relacionadas à defesa ou a um estado de adaptação. Esta mudança ocorre com a participação de fatores de ranscrição, proteínas que regulam a transcrição de determinandos genes. A família Whirly compreende fatores de transcrição que possuem a capacidade de se ligar ao ssDNA e apresentam-se na forma de tetrameros. Esta família tem papel na proteção ao DNA e formação de nucleóides em cloroplastos e mitocôndrias. Outra característica importante é o transporte das proteínas Whirly do cloroplasto para núcleo, em um processo conhecido como sinalização retrógrada, que está relacionado à resposta a estresses como excesso de luz e ataque por patogenos. Em soja não há, ate o momento, nenhum estudo sobre esta importante família. Assim este trabalho visa o estudo desta família em soja, e tras no capítulo 1uma revisão sobre a familia Whirly com ênfase a resposta a estresses bióticos. No capitulo dois a família Whirly de soja é descrita e a expressão de GmWHY1A é analisada durante resfriamento e após infecção por Phakopsora pachyrhizi. A família Whirly em soja é composta por 18 membros, codificados por sete loci. Os membros foram nomeados com base na similaridade com proteínas Whirly de Arabidospsis thaliana e em análises in silico. Foram divididos em três grupos: 1- com localização predita para o croloplasto; 2- preditas como mitocondriais, e 4- formado por proteínas com localização indeterminada. Cada gene teve sua expressão mensurada em raízes, caule, cotilédones, folhas e trifólios. GmWHY1A foi escolhido para estudos posteriores pelas suas características de expressão e pela similaridade com AtWNHY1. GmWHY1foi reprimido após tratamento com etefon e foi positivamente regulado apos tratamento com Acido salicílico e jasmonato. Durante o estresse por frio e após a infecção por Phakopsora pachyrhizi, GMWHY1A foi reprimido. Tomados em conjunto esses dados sugerem que a expressão de Whirly pode ser regulada através do contato com o fungo.
When submitted to stress, plants triggers complex defense pathways that result in expression of defense-related proteins. This change occurs with the participation of transcription factors, proteins that regulates the transcription of specific genes. The Whirly family comprises transcription factors which have the ability to bind single-stranded DNA and remains as tetramers. This family has a role in DNA protection and formation of nucleoids in chloroplasts and mitochondria. Another important feature is the transport of the Whirly proteins from chloroplast to nucleus in a process known as retrograde signaling, which is related to the response to stresses such as high light and pathogen contact. So far there is no study of this important family in soybean. Thus, this work aims to study this family in soybean. The chapter 1 is a review on the Whirly family with emphasis on biotic stress response. In chapter two, the soybean Whirly family is described and the expression of GmWHY1A is analyzed during chilling stress and after infection by Phakopsora pachyrhizi. The Whirly family in soybean comprises 18 members, coded by seven loci. Members were named based on its similarity to Whirly proteins of Arabidospsis thaliana and in silico analyses. They were divided into three groups: 1- with chloroplast predicted location; 2 - predicted as mitochondrial, and 4 - formed by proteins with undetermined location. Each gene had its expression measured in roots, stem, cotyledons, leaves and trifoliate leaves. GmWHY1A was chosen for further studies for its expression characteristics and its similarity to AtWNHY1. GmWHY1 was repressed after treatment with ethephon and was upregulated following treatment with salicylic acid and jasmonic acid. During chilling stress and after infection by Phakopsora pachyrhizi, GMWHY1A was suppressed. Taken together, these data suggest that Whirly expression can be regulated by contact with this fungus.
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Ezzeddine, Dhaker. „Modélisation du comportement dynamique d'un train de tiges de forage pétrolier : application aux vibrations latérales“. Thesis, Paris, ENMP, 2013. http://www.theses.fr/2013ENMP0053/document.
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Les vibrations des systèmes de forage pétrolier sont à l'origine de nombreux dysfonctionnements (ruptures des tiges par une fatigue accélérée, réduction des performances, endommagement des outils de mesures, endommagement des parois du puits, etc.). Face à la complexité des puits forés aujourd'hui, la maîtrise des vibrations des systèmes de forage est plus que jamais un enjeu majeur dans la réussite économique d'un projet pétrolier. Durant l'opération de forage, les tiges en rotation entrent en interaction avec les parois du puits (tubage et/ou formation) et encaissent dans certains cas des vibrations sévères. On distingue généralement trois modes de vibrations suivant le plan de leur occurrence : axiales, latérales et de torsion. Nous ne nous intéressons dans ce mémoire qu'aux vibrations latérales des tiges de forage. Si les vibrations latérales ont fait l'objet de nombreuses études dans le passé, il reste néanmoins des axes d'amélioration possible, tant sur la compréhension des phénomènes (contact garniture-puits par exemple) que sur la recherche de méthodes numériques permettant de réduire les temps de calcul. Dans le cadre de cette thèse, un modèle a été développé pour étudier les vibrations latérales des garnitures de forage dans des forages à trajectoires complexes. Ce modèle permet de prédire les vibrations latérales des tiges pour des paramètres opératoires donnés (vitesse de rotation, poids sur l'outil de forage). Un modèle numérique en éléments finis a été développé pour résoudre les équations du mouvement et analyser ainsi la sensibilité des vibrations aux paramètres opératoires du forage en particulier la vitesse de rotation et l'effort axial dans les tiges. Le modèle permet en outre d'analyser la réponse dynamique d'une garniture en cours du forage (conception). En outre, cette étude a permis de mieux élucider le phénomène sévère de précession des tiges (whirling), très nuisible à l'intégrité mécanique des systèmes de forage. Un nouveau banc d'essais a été mis au point par le Centre de Géosciences de Mines ParisTech pour reproduire les vibrations latérales, mieux comprendre le phénomène du whirling et valider les résultats numériques du modèle. Par ailleurs, des mesures dynamiques en surfaces et en fond de puits au cours de forages réels ont été analysées afin de mettre en évidence les vibrations latérales les plus sévères et en particulier le whirling. Ces données de terrain ont permis de comparer les fréquences propres du système mesurées et celles fournies par le modèle numériqueDrillstring vibrations are commonly observed during oil & gas well drilling operations. Vibrations are a major cause of drilling tools dysfunction (drillstring breaking because of fatigue, reduced drilling efficiency, measurement-while-drilling tools failure, damaging of drill bits, etc.). Because of the increasing complexity of oil & gas wells drilled nowadays, operators need to mitigate efficiently the drillstring vibrations in order to successfully achieve the drilling process. During the drilling operation, rotating drillstrings are in interaction with the well borehole (casing and/or rock) which may lead to severe vibrations. Different vibrations modes occur simultaneously while drilling, we identify mainly three modes: axial, torsional and lateral. This work deals only with lateral vibrations. Literature survey papers show numerous experimental and numerical studies carried out on drillstring dynamics. The developed models don't take into account sufficiently the complex drillstring-borehole interactions or the efficient numerical methods needed to reduce the computation time. A new drillstring dynamics model has been developed within this thesis in order to compute the lateral vibrations of drillstrings in a complex well trajectory. Given the operating parameters (rotary speed, weight on bit) the model predicts the dynamics response of the drillstring in terms of lateral vibrations. A finite element model has been implemented to solve for the equations of motion of the dynamics model and study the dependence of the lateral vibrations on some operating parameters of the system, mainly the rotary speed and the axial load on the drillstrings. The finite element model can be used to compute and enhance the dynamic response of a given drillstring configuration for design issues. Besides, the model can be used to understand some dynamic phenomena encountered while drilling (post-analysis). Moreover, this study was useful to better understand the “whirling” phenomenon which is very harmful for the drilling system components. A new lateral vibrations simulator was built at Mines ParisTech in order to understand the whirling phenomenon and validate the numerical results provided by the dynamics model. Surface and downhole fieldmeasurements have been analyzed in order to understand the occurrence of whirling. The eigenfrequencies evaluated from the field data have been found very close to those provided by the dynamics model
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Pearson, Claire M. „The whirlwind : mothers' experiences of parenting a child with attention deficit hyperactivity disorder“. Thesis, University of Leicester, 1999. http://hdl.handle.net/2381/31287.
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The aim of this research was to generate a grounded theory of how mothers of children with Attention Deficit Hyperactivity Disorder (ADHD), experience parenting their child. Interviews were conducted with eight mothers who all had at least one child with ADHD who was under seven years of age. The period that had elapsed since diagnosis ranged from two months to four years. The interview data was analysed using the grounded theory method. Analysis revealed that the mothers' main task from pre- diagnosis to four years post diagnosis was to 'adapt' to their child. The mothers had to adapt to the effects of having a child with ADHD, they had to adopt new coping strategies and there was also found to be adaptation taking place in the wider systems, such as health and education. Findings suggest that there is a developmental trajectory of how mothers adjust to this disorder over time. Recommendations are made for the implementation of multi-disciplinary assessment for ADHD and the use of groups for mothers focusing on behaviour management, attachment issues and the building up of relationships between the mothers.
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Dinc, Nefin. „Documentary Film: I Named Her Angel“. Thesis, University of North Texas, 2005. https://digital.library.unt.edu/ark:/67531/metadc4736/.
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Recent political developments in the world show us that different cultures need to know and understand each other better. Even though technological developments like the Internet, satellites, cable television and conglomeration of big media entities have made mass communication more effective and faster, we cannot easily say that these developments help to bring world cultures together. As a result, mass audiences are not very much able to see what few productions do speak to these issues in a constructive manner. The main aim of this documentary film project is to serve as a small step towards helping different cultures to understand each other better. This documentary film conveys the basics of Mevlevism by following the formal gatherings of a Mevlevi den in Istanbul, Turkey. A den or tekke is a place where Islamic people gather and perform their religious activities. During these gatherings they do the sema, they pray, they listen to music, and they discuss spiritual matters. Sema is the entire ritual they perform as part of their ceremonies including listening to music, singing and chanting to attain a state of religious emotion and ecstasy or vecd. The documentary film is structured around a twelve year old girl, Elif, who is learning the basics of Mevlevism. The interviews conducted with regulars from the den explain to the audience why people are attracted to this belief system. Filming the ceremonies at the 550-year-old Mevlevi temple in Galata, Istanbul accentuates the historic background of this belief system. The Night of Reunion is the day in which Mevlevis celebrate the passing of Mevlana Celaleddin Rumi, the founder of Mevlevism and provides the climax of the film. Elif performs on that night, a very important moment in her spiritual life.
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Taner, Melis. „"Caught in a Whirlwind:" Painting in Baghdad in the Late Sixteenth-Early Seventeenth Centuries“. Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493409.
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Throughout the sixteenth and seventeenth centuries, the province of Baghdad changed hands between the Aq Qoyunlu Turkmen tribal confederation, the Safavids and the Ottomans. From the last decade of the sixteenth to the first few years of the seventeenth centuries, there was a florescence of art production in Baghdad, at a time when the province was under Ottoman rule. This dissertation focuses on a period of rivalry and exchange between the Sunni Ottoman and the Shiʿite Safavid dynasties in the late-sixteenth and early-seventeenth centuries and elucidates the appearance and disappearance of a lively, yet short-lived, art market in the frontier province of Baghdad. A close study of the corpus of over thirty illustrated manuscripts, often described as exhibiting an “eclectic” style, and produced in Baghdad within a decade, shows that there was a broadening base of patronage as well as an open market for the purchase of art.
While scholarship on the art of the book in Baghdad considers the corpus of illustrated manuscripts solely from the perspective of an Ottoman “context,” this dissertation takes a broader, transregional perspective and studies the art market in Baghdad through the complex layers of Ottoman and Safavid relations. It questions notions of a “school” of painting and emphasizes movement and encounters instead. It also proposes that in the context of an early modern consolidation of imperial identity (represented purposefully distinctly through monumental architecture, painting, decoration, objects in the Ottoman, Safavid and Mughal empires), Baghdad as a frontier province between the Ottomans and the Safavids challenges notions of cultural, ornamental and decorative idioms. Its hybridity is the very product of the “whirlwind” of affairs between the Ottomans and the Safavids.
The dissertation begins with a study of Ottoman-Safavid relations from the last quarter of the sixteenth to the first quarter of the seventeenth centuries. Making use of an unpublished history of Baghdad along with other published and unpublished chronicles, it presents an overview of the complex relations between the two rival empires as well as between the center, Istanbul and the province, Baghdad. This sets the background to the following chapters. Chapter 2 concentrates on a group of single-page paintings produced in Baghdad, which have heretofore escaped scholarly attention. These paintings bespeak a broadening base of patronage as well as an increasing interest in collecting art. The following chapter concerns illustrated popular religious literature, which constitutes the majority of manuscripts produced in Baghdad. It raises questions on the use of models, repetition of compositions and production of illustrated manuscripts for the speculative market. The fourth chapter takes a different turn and concentrates on the patronage of one of the eminent governors of Baghdad, Sokolluzade Hasan Paşa (d. 1602). Focusing on the ambitious project of an illustrated universal history, which was composed for this governor by a Baghdadi author, this chapter deals with the conception of history in the province. The final chapter brings attention to a group of illustrated genealogies most likely produced for the open market. These Ottoman-Turkish genealogies place the Ottoman dynasty as the pinnacle of history. However, one early-seventeenth-century manuscript in Persian turns the genre on its head and presents a pro-Safavid view through text and image within a largely Ottoman genre. Alterations done to its text to then suit a possible Ottoman owner highlight the in-betweenness of Baghdad.History of Art and Architecture
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Hipp, James W. (James William) 1956. „The Maximum Size of Combinatorial Geometries Excluding Wheels and Whirls as Minors“. Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc330849/.
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We show that the maximum size of a geometry of rank n excluding the (q + 2)-point line, the 3-wheel W_3, and the 3-whirl W^3 as minor is (n - 1)q + 1, and geometries of maximum size are parallel connections of (q + 1)-point lines. We show that the maximum size of a geometry of rank n excluding the 5-point line, the 4-wheel W_4, and the 4-whirl W^4 as minors is 6n - 5, for n ≥ 3. Examples of geometries having rank n and size 6n - 5 include parallel connections of the geometries V_19 and PG(2,3).
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Kelley, Garry O'Neal. „Identification, quantification, and localization of protease genes expressed by Myxobolus cerebralis and their potential role in the pathogenesis of whirling disease /“. For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2003. http://uclibs.org/PID/11984.
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Oetke, Svenja [Verfasser]. „Die Kompaktierung der Nukleoide in Chloroplasten der Gerste (Hordeum vulgare L.) durch WHIRLY1 / Svenja Oetke“. Kiel : Universitätsbibliothek Kiel, 2016. http://d-nb.info/1122110979/34.
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Golin, Serena. „The Mitochondrial Protein Whirly2 Regulates Seed Germination and Early Stages of Growth in Arabidopsis Thaliana“. Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3422300.
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Variations in amount and structural integrity of organellar DNA are tightly regulated by nuclear-organelle cross-talk. Whirly proteins are DNA binding proteins that were shown to play a role in organellar DNA maintenance and organization [Marechal et al. 2008; Cappadocia et al 2010]. Arabidopsis thaliana has three Whirly proteins with different subcellular localization: Whirly1 and Whirly3 are targeted to chloroplasts, while Whirly2 is targeted to mitochondria [Krause et al. 2005]. WHIRLY2 gene expression is related to early plant development, being expressed in imbibed seeds, shoot apex and roots of young seedlings. A T-DNA insertional mutant for the WHIRLY2 gene shows an obvious phenotype on seeds, germination and early stages of plant growth. At subcellular level Whirly2 regulates mitochondria morphology, dynamics and functionality of the electron transport chain. Transmitted electron microscopy (TEM) revealed that Whirly2 is a major mitochondrial nucleoids organizer, and it influences both mtDNA and ptDNA copy number. Moreover, our results suggest a coordination of WHIRLY genes that controls expression of target genes of organellar signals upon development and stress conditions.Le variazioni della quantità e dell'integrità strutturale del DNA degli organelli sono strettamente regolate dal cross-talk tra i vari compartimenti subcellulari. Le proteine Whirly sono in grado di legare il DNA ed è stato dimostrato come esse abbiano un ruolo chiave nel mantenimento e nell’organizzazione strutturale del DNA degli organelli [Marechal et al. 2008; Cappadocia et al 2010]. Arabidopsis thaliana possiede tre proteine Whirly con diversa localizzazione subcellulare: Whirly1 e Whirly3 localizzano nei cloroplasti, mentre Whirly2 localizza a livello mitocondriale [Krause et al. 2005]. È stato osservato come l’espressione del gene WHIRLY2 sia modulata durante la crescita della pianta. In particolare, WHIRLY2 è maggiormente espresso nei semi imbibiti e nei meristemi apicali e radicali. Il mutante inserzionale per il gene WHIRLY2 presenta infatti, un chiaro fenotipo nello sviluppo del seme e nella germinazione. A livello subcellulare, Whirly2 regola la morfologia, la dinamica e la funzionalità mitocondriale. Inoltre, è stato rilevato come Whirly2 sia indispensabile nel mantenimento strutturale dei nucleoidi mitocondriali e del contenuto DNA negli organelli. In aggiunta, i nostri risultati suggeriscono un coordinamento nell’espressione dei geni WHIRLY con lo scopo di mantenere un’adeguata omeostasi cellulare sia durante lo sviluppo che in condizioni di stress.
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Soliman, Hatem Mohamed Touhan. „Construction and Screening of an Expression cDNA Library from the Triactinomyxon Spores of Myxobolus cerebralis, the causative agent of Salmonid Whirling Diseases“. Diss., lmu, 2005. http://nbn-resolving.de/urn:nbn:de:bvb:19-39819.
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Cazan, Adrian Mirel. „Reduction of whirl instability in externally pressurised gas journal bearings“. Thesis, Kingston University, 2002. http://eprints.kingston.ac.uk/20696/.
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One major limitation in the use of externally pressurized air bearings (EPB) is their susceptibility to vibrations problems. The most destructive vibration that develops in a gas bearing is self-excited whirl, which commences when the damping force in the bearing becomes zero. The main aim of this research was to undertake a theoretical investigation of cylindrical whirl in a balanced vertical axis EPB, and ways of delaying its onset. In order to do this, it was necessary firstly to find the bearing static stiffness and damping coefficients by means of a compressible flow analysis of the gas. To do this, by employing Mathematica, a novel approach used the 'shooting method' in order to solve the governing differential equation (which included functions of a complex variable). The results obtained compared very favourably with previous theoretical published work that had employed finite difference methods. Having found the bearing coefficients, it was possible to solve the bearing dynamic differential equations and thus create stability maps. This procedure was carried out on various bearing arrangements aimed at raising the stability threshold. These included: A series arrangement involving a non-rotating externally pressurized sleeve round the rotor as well as a series arrangement in parallel with the main bearing. The series-parallel configuration resulted in a bearing with a threshold speed and stiffness between the extremes of a simple EPS and a series EPB, all three designs being of the same length. An optimum adjustment of the series-parallel geometry, created threshold speeds three to four times that of a simple version. This in itself was an excellent achievement. Finally, a further increase in threshold frequency, up to seven times that of an equivalent simple EPB, was attained by an additional novel design round the sleeve of a passive eddy current magnetic damper.
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Zanin, Daniel Bispo. „Metodologia de análise de whirl flutter utilizando o MSC/NASTRAN“. Instituto Tecnológico de Aeronáutica, 2011. http://www.bd.bibl.ita.br/tde_busca/arquivo.php?codArquivo=2990.
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O whirl flutter é um fenômeno aeroelástico característico de aeronaves com motores a hélice. Trata-se da instabilidade do movimento de precessão da hélice devido ao acoplamento dos deslocamentos de arfagem e guinada em conjunto com a atuação das forças aerodinâmicas, que alimentam as oscilações do sistema. Inicialmente, o presente trabalho busca entender este mecanismo de flutter através de uma revisão bibliográfica e da obtenção das equações de movimento para um sistema simples com dois graus de liberdade. A seguir, apresenta-se uma metodologia para os cálculos de whirl flutter com o uso do software comercial MSC/NASTRAN. O processo é aplicado ao estudo de caso de uma aeronave bimotora de pequeno porte, utilizando um modelo de elementos finitos para a estrutura de fixação do motor. A introdução dos efeitos giroscópicos e aerodinâmicos da hélice é proporcionada por um pré-processador externo, que também tem o seu funcionamento apresentado. As respostas do NASTRAN para o estudo de caso são então comparadas aos resultados de um programa específico para o cálculo de whirl flutter.
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Bass, Cameron M. 1982. „Redesign of the double hand rim modification of the "Whirlwind" Wheelchair for manufacture in developing nations“. Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/32802.
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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2004.Includes bibliographical references (p. 32).
In this thesis, I investigate possible improvements to the design of a wheelchair for manufacture in a developing nation, specifically one designed for use by persons with hemiplegia. Ralf Hotchkiss's "Whirlwind" Wheelchair is currently manufactured with local materials in many developing nations. It provides both an affordable source of quality wheelchairs for the populace as well as a source of employment. J.A. van Alphen and D.R. Arbib made modifications to the original Wheelchair design so that it would be usable by hemiplegics. However, on manufacture in Duranguito, Mexico, the chair was deemed unusable due to certain flaws. After analyzing the design of the chair, potential solutions for the two most critical problems are suggested, taking care to avoid undue increases in cost or complexity of manufacture.
by Cameron M. Bass.
S.B.
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Baumgartner, Christopher M. „A Performance Analysis of Whirlwind and Shadow Rituals, Ticheli Composition Contest Award Winning Works in 2007“. Bowling Green State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1236102703.
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Herrmann, Andrew F., Julia Barnhill und Mary C. Poole. „The Scoobies, The Council, The Whirlwind, The Initiative: Portrayals of Organizing in Buffy The Vampire Slayer“. Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/820.
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With the 2012 releases of The Cabin in the Woods and The Avengers, writer/director Joss Whedon moved beyond his cult status and into the mainstream. His cult television work, however, remains admired in both the popular imagination and in the academic world of popular culture studies. This year’s CSCA13 corresponds with the ten-year anniversary of the cancellation of Whedon’s first successful cult television show, Buffy the Vampire Slayer. Whedon’s other work, including Firefly, Dr. Horrible’s Sing-Along-Blog, Dollhouse, Angel, etc., are not only cult fan favorites, but favorites in popular culture academia. The participants on this panel will explore various aspects of Whedon and the Whedonverse, including: Whedon’s rhetorical framing regarding his transformation from cult director to mainstream phenom; his genre-bending frameworks across his various projects; his examination of gender roles; exploring and exploding Whedon’s use of mythology; and how Whedon’s characters manage to out-organize formal organizations.
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Uneeb, Mohammed. „Theoretical investigation of whirl instability in externally pressurized gas journal bearings“. Thesis, Imperial College London, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243270.
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Nielsen, Finn Sivert. „Eye of the whirlwind Russian identity and Soviet nation-building. Quests for meaning in a Soviet metropolis /“. Click here to access, 1987. http://www.anthrobase.com/Txt/N/Nielsen_F_S_03.htm.
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First publication of a revised edition of the author's M.A. Thesis (Institute of Social Anthropology, University of Oslo, 1987).Includes bibliographical references (p. 320-336). Also available in print.
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Payne, Alison Jane. „"It has hit us like a whirlwind" : the impact of commercial television advertising in Britain 1954-1964“. Thesis, Birkbeck (University of London), 2016. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.720360.
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The Chairman of the advertising agency, Foote, Cone and Belding, claimed that the launch of the new advertising medium of commercial television, in 1955, was a ’whirlwind’ for his industry. New disciplines, new techniques, and new relationships with the production industry had to be established, and existing campaigns in press had to be transferred to television, an advertising medium that London agencies had no experience with. Also, for the first time, agencies had to work within a regulatory process established by legislation, and policed by the Independent Television Authority. The Authority was tasked with a public service remit to protect citizens both as viewers of television and the consumers of branded goods. The acceptance of viewers, of the commercials on this new television channel. was central to the concerns of both the advertising industry and the regulator. To identify the extent of the impact of commercial television advertising, on the advertising industry, advertising regulation and the viewers, this thesis draws on contemporary research carried out by the BBC, archival material from the regulatory authority and the representative organisations of the advertising industry, and the trade press, and combines this with new interviews with practitioners, working in the advertising and television industries, from 1954-1964. Using material from advertising archives, the thesis also examines the advertising of one important category of advertised goods, washing powders, to identify how the advertising agencies evolved their clients’ advertising, from press, to the new advertising medium of television.