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Auswahl der wissenschaftlichen Literatur zum Thema „WH 220“
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Zeitschriftenartikel zum Thema "WH 220"
Devrifqi, Uray Muhammad, und Muhammad Imbarothur Mowaviq. „Rancang Bangun Pembangkit Listrik Hybrid Tenaga Surya dan Bayu Untuk Simulasi Pompa Aerator Kolam 25 W“. SUTET 11, Nr. 1 (28.06.2021): 36–50. http://dx.doi.org/10.33322/sutet.v11i1.1455.
Der volle Inhalt der QuelleMyung, Seung-Taek, und Ji Ung Choi. „Mn-Rich P′2-Na0.67[Ni0.1Fe0.1Mn0.8]O2 As High-Energy-Densityand Long-Life Cathode Material for Sodium-Ion Batteries“. ECS Meeting Abstracts MA2023-02, Nr. 4 (22.12.2023): 580. http://dx.doi.org/10.1149/ma2023-024580mtgabs.
Der volle Inhalt der QuelleJackson, Bradford E., Marc E. Emerson, Lisa P. Spees, Chris D. Baggett, Hayley N. Morris, Ana I. Salas, Angelo Moore et al. „Abstract B106: Assessing racial disparities in the receipt of quality care in the most prevalent cancers in American Indians“. Cancer Epidemiology, Biomarkers & Prevention 32, Nr. 12_Supplement (01.12.2023): B106. http://dx.doi.org/10.1158/1538-7755.disp23-b106.
Der volle Inhalt der QuelleBen Ayed, Layla, Wenli Yang, Giovanni Widmer, Vitaliano Cama, Ynes Ortega und Lihua Xiao. „Survey and genetic characterization of wastewater in Tunisia for Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi, Cyclospora cayetanensis and Eimeria spp.“ Journal of Water and Health 10, Nr. 3 (30.05.2012): 431–44. http://dx.doi.org/10.2166/wh.2012.204.
Der volle Inhalt der QuelleScheller, Maximilian, Axel Durdel, Alexander Frank und Andreas Jossen. „Model-Based Performance Evaluation of Hybrid Solid-State Batteries: Impact of Laser-Ablated Geometrical Structures“. Batteries 10, Nr. 11 (05.11.2024): 392. http://dx.doi.org/10.3390/batteries10110392.
Der volle Inhalt der QuelleSánchez, Héctor, Katherine Domenech, Gerardo Rivera, Melvin Pagán, Américo Casas, Paul F. Randel und Gladycia Muñiz. „Comparison of body dimensions between normal and double muscled Senepol heifers“. Journal of Agriculture of the University of Puerto Rico 101, Nr. 1 (05.04.2021): 17–34. http://dx.doi.org/10.46429/jaupr.v101i1.14291.
Der volle Inhalt der QuelleSebayang, Abdi Hanra, Aditya Pangestu und Rico Aditia Prahmana. „UNJUK KERJA MOTOR BENSIN GENERATOR-SET BERBAHAN BAKAR CAMPURAN BIOETANOL NIRA TEBU“. Scientific Journal of Mechanical Engineering Kinematika 7, Nr. 2 (30.12.2022): 98–107. http://dx.doi.org/10.20527/sjmekinematika.v7i2.233.
Der volle Inhalt der QuelleHu, Hao, Xiaogang Sun, Wei Chen, Jie Wang, Xu Li, Yapan Huang, Chengcheng Wei und Guodong Liang. „Electrochemical Properties of Supercapacitors Using Boron Nitrogen Double-Doped Carbon Nanotubes as Conductive Additive“. Nano 14, Nr. 07 (Juli 2019): 1950080. http://dx.doi.org/10.1142/s1793292019500802.
Der volle Inhalt der QuelleSaeed, Muhammad Sajid. „Investigating the Extent to Which Personality Traits and Demographics Affect Job Satisfaction“. Business and Management Horizons 4, Nr. 1 (31.05.2016): 70. http://dx.doi.org/10.5296/bmh.v4i1.9535.
Der volle Inhalt der QuelleAnisa, Zuffa, und Erwanto Erwanto. „POTENSI PEMBANGKIT LISTRIK TENAGA AIR HUJAN PLTAH SEBAGAI SUMBER ENERGI LISTRIK PIRANTI ELEKTRONIK RUMAH TANGGA“. Jurnal Rekayasa Mesin 15, Nr. 2 (15.08.2024): 1053–65. http://dx.doi.org/10.21776/jrm.v15i2.1671.
Der volle Inhalt der QuelleDissertationen zum Thema "WH 220"
Renaude, Elodie. „Stratégies de modulation épigénétique des lymphocytes T CD4 afin de potentialiser l’efficacité des immunothérapies anticancers“. Electronic Thesis or Diss., Bourgogne Franche-Comté, 2024. http://indexation.univ-fcomte.fr/nuxeo/site/esupversions/cf4a5ba6-33d1-4c40-ae32-3c46985a1213.
Der volle Inhalt der QuelleCD4 T-cells are necessary for the establishment of an efficient anti-cancer response by providing help for the priming and persistence of tumor-specific cytotoxic T lymphocytes. However, the prognosis of patients can be differently affected, depending on CD4 T-cell subtypes infiltrating the tumor (TIL). Epigenetics take an important part in : i) the regulation of CD4 T-cells polarization, ii) plasticity towards other subsets and iii) maturation. It has been shown before that epigenetic modulators could regulate CD4 T-cells differentiation. Thus, the treatment of CD4 T-cells by epigenetic therapies can be used as a strategy to improve immunotherapy. Our results confirmed the presence of Th17-cells in expanded T-cells issued from liver metastases of colorectal cancer. Moreover, the number of expanded Th17-cells among total TIL was inversely correlated with patients' survival. We then attempt to evaluate the effect of epigenetic regulators on both CD4 T-cells differentiation and function. A screening of a bank of epidrugs allowed us to identify a Sirtuin 1 activator, Agrimol B, that might downregulate proliferation, cytokine secretion and CCR6 expression on CD4 T-cells. Our results thus indicated that Agrimol B might regulate the migration and the functionality of Th17-cells from healthy donors. Mechanistically, the inhibition of caspases by our molecule could prevent the cleavage of Sirtuin 1 and thus maintain its activity compared to control conditions. Together, this work aims to uncover the role of epigenetics in the regulation of CD4 T-cell subsets in order to potentiate the effectiveness of cancer immunotherapy
Yan, Nicole. „Integrating point-of-care testing (POCT) for HIV, syphilis, malaria and anaemia into antenatal care services at dispensaries in western Kenya“. Thesis, Liverpool School of Tropical Medicine, 2018. http://archive.lstmed.ac.uk/9471/.
Der volle Inhalt der QuelleWarda, Walid. „Ciblage de la cellule souche leucémique exprimant la protéine lL-1RAP : Approche d'immunothérapie anti-tumorale utilisant des lymphocytes T génétiquement modifiés pour exprimer un récepteur chimérique à l’antigène(CAR)“. Thesis, Bourgogne Franche-Comté, 2018. http://www.theses.fr/2018UBFCE002/document.
Der volle Inhalt der QuelleChronic myeloid leukemia (CML) is a myeloproliferative disorder and is characterized by the presence of a Philadelphia chromosome (Phl) encoding the BCR-ABL fusion protein with constitutive tyrosine kinase activity. The treatment by Tyrosine Kinase lnhibitors (ITK) is not curative. The problem today is ta target leukemic stem cells (HSCs) to prevent relapse of patients after stopping treatment with TKI and permanently eradicate the disease. Studies have identified the interleukin-1 accessory protein receptor (IL-lRAP) as a potential target for killing CSL (BCR-ABL1 positive) in CML or in acute myeloid leukemia (AML). We therefore propose to develop a cell therapy approach targeting IL-lRAP, using T cells (LT) redirected by a CAR (Chimeric Antigen Receptor) in the treatment of CML and AML. We produced a specific anti-lL-1RAP murine monoclonal antibody (mAb) called # A3C3. We tested the specificity of the antibody # A3C3 in flow cytometry, in Western blot, by immunohistochemistry or confocal microcopy, on positive human cell lines IL-1RAP (KU812) or IL-1RAP negative (Raji). Moreover, by using this antibody, we have demonstrated by immunohistochemistry, on 20 different normal tissues that our antibody does not recognize or very few non-specific (off-target) targets. Finally, we demonstrated that this antibody is able to detect positive IL-1RAP CSLs in primary bone marrow or peripheral blood samples of LMC patients at diagnosis or after ITK treatment. By molecular biology, we have sequenced and identified rearrangements of the heavy (lgH) and light {lgL) chains coding region for hypervariable regions of# A3C3. The coding sequence for the "single chain variable fragment" (scFv), lin king the 2 lgH and lgl chains, was cloned into a 3rd generation lentiviral skeleton securised by a suicide gene, inducible caspase 9 (iCASP9). We produced CART-cells and LT-mock ex-vivo. The transduction efficiency is measured by CD3 + / CD19 + expression (82% on average, n = 5), in flow cytometry. The functionality of the suicide cassette iCaspase9/AP1903 on CART-cells after 48h treatment with AP1903 was tested. We have shown the death of more than 90% of CART-cells (7-AAD labeling in flow cytometry). We then performed in-vitro functional tests of CART-cells against LMC lines naturally expressing IL-1RAP or against transfected lines to express the membrane form of IL-1RAP. After co-culture of CART-cells in the presence of IL-1RAP + target cells, we have shown that they proliferate (CFSE test), that they secrete interferon y and inflammatory cytokines (intracellular labeling and Cytokines Bead Array assay). They are able to degranulate (CD107a & b labeling). Finally, by 7 AAD labeling, we demonstrated the cytotoxicity of CART-cells against IL1-RAP + cells. Finally, we showed the effectiveness of CART-cells in vivo, in a tumor xenograft model in NSG immunodeficiency mice engrafted by the K562-IL1RAP+/Luciferase+ line. There is a decrease in the tumor load 4 days after injection of CART-cells, until complete disappearance.This proof of concept suggests alternative therapeutic perspectives in the treatment of CML or AML, which should be optimized in murine models (sequence and injection numbers, cell numbers, associations with ITKS or other chemotherapies) in order to Phase I clinical trial, to demonstrate the feasibility and safety of the approach to consider a demonstration of efficacy in human. Securing by the suicide cassette makes it possible to consider the use of CART-cells in an autologous or allogeneic situation (Donor Lymphocytes infusion, DU)
Dosset, Magalie. „Caractérisation et influence des lymphocytes T CD4 anti-télomérase dans les cancers“. Thesis, Besançon, 2012. http://www.theses.fr/2012BESA3014/document.
Der volle Inhalt der QuelleRecent advances in immunology have now validated the concept of cancer immunosurveillance and the leading role of adaptative T cell immunity. Until a few years ago, antitumor CD8 T cell responses have been the most studied due to their direct cytotoxic activity on tumor cells. On the other hand, study of antitumor CD4 T cell responses are even more challenging because of the heterogeneity and plasticity of the various CD4 T cells subpopulations described. Among them, CD4 T helper type-1 cells (Th1), mainly characterized by the production of IFN, control the activation of antitumor cellular immunity. Thus, stimulation of specific CD4 Th1 cells may have a major interest for the development of anticancer immunotherapies. During this research thesis, we characterized novel HLA class II epitopes derived from a relevant tumor antigen, telomerase (TERT), and studied their capacities to stimulate specific CD4 Th1 cell responses. Using a method based on predictive immunology, we identified 4 peptides derived from TERT, referred as « Universal Cancer Peptides » (UCPs), enable to bind the most commonly found HLA-DR alleles in human. Using HLA-A2/HLA-DR1 transgenic mouse model, we first evaluated the in vivo immunogenicity of these peptides. Immunization of mice with UCPs induces high avidity specific CD4 T cells. The study of their polarization showed that UCP-specific CD4 T cells do not produce IL-4, -5, -10 or -17 cytokines, excluding a Th1, Treg or Th17 differentiation. In contrast, we measured high amount of IFN and IL-2 which characterize a Th1 pattern. The study of helper role allow us to demonstrate that CD8 peptide-based vaccinations in presence of UCPs enhance the efficacy of tumor specific CTL responses. Indeed, the intensity of these responses is strongly correlated with that of UCP-specific CD4 T cells induced in vivo. Furthermore, the stimulation of UCP-specific CD4 T cells promotes activation and IL-12 release by dendritic cells through a mechanism that involves IFN, GM-CSF and CD40L. We also demonstrated the antitumor efficacy of UCPs during a therapeutic vaccination in mice, as well as their capacity to foster the recruitment of specific CD8 T cells at the tumor site. In addition, the presence of naturally occurring UCP-specific CD4 T cell responses was found in different types of cancers such as leukemia, lung, colorectal or renal cancers. A study conducted in a cohort of 84 metastatic lung cancer patients revealed a synergistic effect of spontaneous UCP-specific CD4 Th1 and chemotherapy-treatment. Altogether, this study provides further evidences that stimulation of antitumor CD4 Th1 cells is a powerful method to improve cancer vaccines and also highlights the interest of TERT-derived UCPs for the innovative monitoring of antitumor CD4 T cell responses
Kvasnička, Karel. „Mobilní zdroje elektrické energie“. Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2020. http://www.nusl.cz/ntk/nusl-413211.
Der volle Inhalt der QuelleLampe, Tina. „SUMOylierung von NFYA“. Doctoral thesis, 2009. http://hdl.handle.net/11858/00-1735-0000-0006-AD2F-6.
Der volle Inhalt der QuelleKiendl, Florian Josef Werner. „Untersuchungen zur Funktion des RanGAP1 Proteins“. Doctoral thesis, 2007. http://hdl.handle.net/11858/00-1735-0000-0006-ACCE-6.
Der volle Inhalt der QuelleAndrei, Maria Alexandra. „Characterization of cytoplasmic bodies involved in 5' to 3' mRNA degradation in human cells“. Doctoral thesis, 2007. http://hdl.handle.net/11858/00-1735-0000-000D-F14A-E.
Der volle Inhalt der QuelleVolland, Sonja. „Die Bedeutung von Stanniocalcin 2 im humanen Neuroblastom“. Doctoral thesis, 2009. http://hdl.handle.net/11858/00-1735-0000-0006-AD54-E.
Der volle Inhalt der QuelleBeisel, Nadine. „Patterns of post-translational histone modifications, chromatin condensation and DNA fragmentation during apoptosis“. Doctoral thesis, 2005. http://hdl.handle.net/11858/00-1735-0000-0006-ABBA-9.
Der volle Inhalt der QuelleBücher zum Thema "WH 220"
STERN, RA. Stern: Information Processing 2ed (BL & Wh) with Enable 2.0 (Book & Software Package). John Wiley & Sons Inc, 1988.
Den vollen Inhalt der Quelle findenPress, Blue Star, und Brita Lynn Thompson. Stickers for Days: 200 Waterproof Stickers for Decorating Laptops, Water Bottles, Surfboards, or Wh Atever Your Heart Desires. Blue Star Press, 2022.
Den vollen Inhalt der Quelle findenBuchteile zum Thema "WH 220"
„Vorwort“. In Linke Satzperipherie und [±wh]-Asymmetrie, IX—X. De Gruyter, 2022. http://dx.doi.org/10.1515/9783110666403-202.
Der volle Inhalt der Quelle„MUSIC LEGENDS (2020) (QN, EJ, DB, WH)“. In Coins of England and the United Kingdom (2022), 359–64. Spink & Son, Ltd, 2022. http://dx.doi.org/10.2307/j.ctv2321j9q.23.
Der volle Inhalt der QuelleSaini, Rohtash, Nischal Sharma und Raju Attada. „Delving into Recent Changes in Precipitation Patterns in the Western Himalayas under Global Warming“. In Global Warming - A Concerning Component of Climate Change [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.1002028.
Der volle Inhalt der QuelleNischal, Rohtash, Sreehari K, Akash Pathaikara, Pravin Punde und Raju Attada. „Hydrological Extremes in Western Himalayas-Trends and Their Physical Factors“. In Natural Hazards - New Insights [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.109445.
Der volle Inhalt der QuelleKonferenzberichte zum Thema "WH 220"
Gonzalez Cruz, Eduardo Manuel, Eduardo Krüger, Leandro Fernandes und Daniel Trento. „RESULTADOS PRELIMINARES DO DESEMPENHO TÉRMICO DE UM SISTEMA DE RESFRIAMENTO RADIANTE CAPACITIVO“. In XVIII ENCONTRO NACIONAL DE TECNOLOGIA DO AMBIENTE CONSTRUÍDO. UFRGS, 2020. http://dx.doi.org/10.46421/entac.v18i.782.
Der volle Inhalt der QuelleLiu, Xuefei, Aijun Li und Yuan Jia. „How does prosody distinguish Wh-statement from Wh-question? A case study of Standard Chinese“. In Speech Prosody 2016. ISCA, 2016. http://dx.doi.org/10.21437/speechprosody.2016-221.
Der volle Inhalt der QuelleHsu, Yu-Yin, und Anqi Xu. „Wh-indeterminates and Prosody in Hong Kong Cantonese“. In 10th International Conference on Speech Prosody 2020. ISCA: ISCA, 2020. http://dx.doi.org/10.21437/speechprosody.2020-77.
Der volle Inhalt der QuelleBodapati, Naga Narendra B., Robert J. Peterman, B. Terry Beck und Chih-Hang John Wu. „Effect of Concrete Properties on Transfer Lengths in Concrete Rail-Road Ties“. In 2014 Joint Rail Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/jrc2014-3859.
Der volle Inhalt der QuelleOrrico, Riccardo, und Mariapaola D'Imperio. „Tonal specification of speaker commitment in Salerno Italian wh-questions“. In 10th International Conference on Speech Prosody 2020. ISCA: ISCA, 2020. http://dx.doi.org/10.21437/speechprosody.2020-74.
Der volle Inhalt der QuelleLo, Roger Yu-Hsiang, und Angelika Kiss. „Durational and Pitch Marking of Rhetorical Wh-questions in Mandarin“. In 10th International Conference on Speech Prosody 2020. ISCA: ISCA, 2020. http://dx.doi.org/10.21437/speechprosody.2020-88.
Der volle Inhalt der QuelleDuryagin, Pavel. „On some factors affecting the choice of tune in Russian wh-questions“. In 10th International Conference on Speech Prosody 2020. ISCA: ISCA, 2020. http://dx.doi.org/10.21437/speechprosody.2020-48.
Der volle Inhalt der QuelleAhmadov, Faig N., und Munira A. Manashova. „The study of WH production using different event generators“. In PROCEEDINGS OF THE 24TH INTERNATIONAL SCIENTIFIC CONFERENCE OF YOUNG SCIENTISTS AND SPECIALISTS (AYSS-2020). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0063390.
Der volle Inhalt der QuelleP. Cremasco, Nicole, Renan De O. A. Takeuchi, Jorge A. Leludak und Jair Urbanetz Jr. „Análise Comparativa de Diferentes Metodologias de Cálculo de Taxa de Desempenho em Sistemas Fotovoltaicos Instalados em Ponta Grossa-PR“. In Congresso Brasileiro de Automática - 2020. sbabra, 2020. http://dx.doi.org/10.48011/asba.v2i1.1579.
Der volle Inhalt der QuelleFadhilah, Tesha Fersty, und Hermawati Syarif. „Grammatical Competence in Constructing Wh-Questions in Reading Comprehension Test: A Proposed Study“. In Ninth International Conference on Language and Arts (ICLA 2020). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/assehr.k.210325.046.
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