Zeitschriftenartikel: „Vcacd“

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Noor, Shazia, Hadeed Ashraf, Muhammad Sultan und Zahid Mahmood Khan. „Evaporative Cooling Options for Building Air-Conditioning: A Comprehensive Study for Climatic Conditions of Multan (Pakistan)“. Energies 13, Nr. 12 (12.06.2020): 3061. http://dx.doi.org/10.3390/en13123061.

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This study provides comprehensive details of evaporative cooling options for building air-conditioning (AC) in Multan (Pakistan). Standalone evaporative cooling and standalone vapor compression AC (VCAC) systems are commonly used in Pakistan. Therefore, seven AC system configurations comprising of direct evaporative cooling (DEC), indirect evaporative cooling (IEC), VCAC, and their possible combinations, are explored for the climatic conditions of Multan. The study aims to explore the optimum AC system configuration for the building AC from the viewpoints of cooling capacity, system performance, energy consumption, and CO2 emissions. A simulation model was designed in DesignBuilder and simulated using EnergyPlus in order to optimize the applicability of the proposed systems. The standalone VCAC and hybrid IEC-VCAC & IEC-DEC-VCAC system configurations could achieve the desired human thermal comfort. The standalone DEC resulted in a maximum COP of 4.5, whereas, it was 2.1 in case of the hybrid IEC-DEC-VCAC system. The hybrid IEC-DEC-VCAC system achieved maximum temperature gradient (21 °C) and relatively less CO2 emissions as compared to standalone VCAC. In addition, it provided maximum cooling capacity (184 kW for work input of 100 kW), which is 85% higher than the standalone DEC system. Furthermore, it achieved neutral to slightly cool human thermal comfort i.e., 0 to −1 predicted mean vote and 30% of predicted percentage dissatisfied. Thus, the study concludes the hybrid IEC-DEC-VCAC as an optimum configuration for building AC in Multan.

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Lin, Wei Min, Hitoshi Ohmori, T. Suzuki, Yoshihiro Uehara, Y. Watanabe und Shinya MORITA. „Characteristics of Free Form Finishing Applying V-CAM System“. Key Engineering Materials 329 (Januar 2007): 273–78. http://dx.doi.org/10.4028/www.scientific.net/kem.329.273.

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A new CAD system, which is called Volume-CAD (VCAD) have been developed. We carried out research and development of VCAD fabrication process based on VCAD/CAM precision control. In this study, a developed V-CAM had been used for a polishing fundamental experiment of a free form surface. The relationship between NC resolution and form accuracy of polished surface are discussed.

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Yozgat, Can Yilmaz, Yanki Celik Yilmazer und Yilmaz Yozgat. „Pulmonary Atresia with Intact Ventricular Septum associated with Ventriculo-Coronary Arterial Communication in a Fetus at 21 Weeks of Gestation“. Case Reports in Obstetrics and Gynecology 2020 (15.07.2020): 1–3. http://dx.doi.org/10.1155/2020/7581483.

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Pulmonary atresia with the intact ventricular septum (PA-IVS) is a rare anomaly that has an absent communication between the right ventricle and pulmonary arterial circulation. PA-IVS has a hypoplastic and hypokinetic and thickened right ventricle with the intact ventricular septum. It can be diagnosed with PA-IVS in routine obstetric ultrasound examination because the four-chamber view of PA-IVS is generally abnormal. The size of the right ventricular cavity is proportional to the Z value of the diameter of the tricuspid valve. The essential associated cardiac finding of PA-IVS is ventricular-coronary arterial communications (VCAC). The hypertensive RV forces blood through the intramyocardial sinusoids with continuous fistulous contact with the epicardial branches of RCA. It is called the VCAC. A color Doppler can detect VCAC due to its location in the pericardium along the coronary artery. If patients have VCAC and tricuspid Z score below -4, all of these conditions are infallible signs of high mortality rates in their fetal or postnatal lives. Our aim in presenting this case is to remind perinatologists if they detect an abnormal four-chamber view of the fetus’s heart, they should also carefully examine whether VCAC exists. Herein, we report a case of PA-IVS and VCAC at 21 weeks’ gestation with fetal echocardiographic images.

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Guzman Barragan, Blanca Lisseth. „Contextos locales de la vigilancia de la calidad del agua para consumo humano en de los países de América Latina: Brasil y Colombia“. Revista de Salud Pública 17, Nr. 6 (19.02.2016): 961–72. http://dx.doi.org/10.15446/rsap.v17n6.40977.

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Analizar comparativamente los sistemas nacionales de vigilancia de la calidad del agua para consumo humano (VCACH) de Brasil y Colombia, con el fin de comprender como están organizadas las prácticas en estos países, sus límites y posibilidades.Métodos: Se utilizó la metodología Cross Nacional, mediante el análisis documental de fuentes secundarias, las cuales fueron obtenidas a través de las instituciones responsables y páginas oficiales. Con el propósito de discutir las convergencias y divergencias entre los dos sistemas, considerando las directrices de la Organización Mundial da Salud. Resultados: Los marcos legales de la VCACH en Brasil y Colombia comienzan a definirse en la década 70-80, coincidiendo con la visibilidad internacional de esta temática. Las prácticas de VCACH en el Brasil estuvieron definidas y organizadas en un programa nacional, lo que solamente se está dando en Colombia recientemente. Las actuales legislaciones avanzan en los componentes que orientan las prácticas de vigilancia, por ejemplo, incorporación de metodologías de evaluación de riesgo. La legislación colombiana establece la regulación de la prestación de los servicios de abastecimiento de agua, aspecto no contemplado en la legislación brasilera. Elementos como descentralización, intersectorialidad, universalidad y el derecho a información son contemplados en las legislaciones de ambos países, aunque las acciones de VCACH necesiten avanzar para la efectiva operatividad de los mismos. Conclusiones: Brasil y Colombia presentan semejanzas en los procesos de definición de la VCACH, estando en momentos distintos de implementación de las acciones de VCACH. Estas son necesarias para garantizar los derechos humanos relacionados con la preservación de ambiente, así como la universalidad del acceso a agua potable en cantidades y en calidad adecuadas, contribuyendo en la promoción de la salud.

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Wang, Changsong. „Asymmetries in two types ofde-related verb-copying constructionsin Mandarin Chinese“. International Journal of Chinese Linguistics 8, Nr. 2 (31.12.2021): 241–90. http://dx.doi.org/10.1075/ijchl.20007.wan.

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Abstract This article studies Chinese V-de sentences from the perspective of verb-copying constructions (VCC) and presents some more evidence in favor of the distinction between descriptive V-de constructions and resultative V-de constructions. VCC with descriptive V-de sentences (VCCD) and VCC with resultative V-de sentences (VCCR) are linearly described as [NP1+ V1+ NP2 + V2 + de +XP]. Five asymmetries, though not very sharp, have been observed between VCCD and VCCR: (a) the movement asymmetry of [V1+NP2], (b) the questioning asymmetry between weishenme ‘why’ and shenme ‘what’, (c) the definiteness asymmetry of NP2, (d) the repetition asymmetry of V1, and (e) the asymmetry of subject-oriented adverb guyi ‘intentionally’. To explain these differences, we assume that [V1+NP2] in VCCD is a constituent, acting as an internal topic. While similar analysis cannot be extended to VCCR. We propose instead that [NP1+V1+NP2] is a constituent in VCCR, projecting further into a complex NP and acting as a sentential subject. These structural differences can well explain the five asymmetries from the island effects, and the semantic and pragmatic constraints (on internal topics and subject-oriented adverbs). Meanwhile, based on the restriction of manner adverbial modification, the V2 in VCCD and VCCR is assumed to be externally merged at the morphological level via External Morphological Merger to satisfy the affixal properties of de. The copying of V1 as V2 is not driven syntactically, but morphologically. This morphosyntactic approach to VCCD and VCCR provides a new perspective to explore V-de sentences and VCC, which may shed light on the morphosyntactic studies of Mandarin Chinese from a crosslinguistic perspective.

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Jain, Sfoorti. „Credit Pit Detection in Subordinate Securities: A French Perspective“. Ushus - Journal of Business Management 18, Nr. 3 (01.07.2019): 65–85. http://dx.doi.org/10.12725/ujbm.48.6.

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The purpose of this research is to prepare a predictive model for identifying credit crisis using an artificial neural network. The paper also aims to find out the driver and driven relationship between various financial instruments like CDS, FRA, IRS, and the Volatility index (VCAC) and government securities for France. The model, thus, is directed towards finding a threshold for credit pit events and linking various events corresponding to that dates where the threshold is breached to validate the accuracy and usefulness of the model. From the research, it is found that for France, the CDS-FRA-VCAC model derives the threshold for VCAC to indicate the probability of credit crisis or financial market crash. It is also found that sovereign bonds have a huge impact on France economy including various derivatives. This is probably why the Eurozone debt crisis impacted France much more than the 2008 financial crash.

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Pasha, Tayyab, Rafaqat Ahmed, Muhammad Amir, Amir Iqbal und Ayesha Siddiqa. „EARLY OUTCOMES“. Professional Medical Journal 23, Nr. 05 (10.05.2016): 583–88. http://dx.doi.org/10.29309/tpmj/2016.23.05.1588.

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Objectives: Off pump TACR/MACR performed in experienced hands hascomparable results to on pump TACR/MACR. Period: January-2012 to December-2015.Material and method: 405 patients with two and three vessel coronary artery disease (two &three VCAD) underwent OPCAB at the department of cardiac surgery, Jinnah hospital, Lahore.73 of them got total or multiple arterial coronary revascularizations. 34 patients (41%) hadtwo VCAD and 47 (59%) had three VCAD. Total arterial revascularization was performed in 70(95.8%) patients using right internal mammary artery and left internal mammary artery and/orradial artery. 3 (4.10%) patients got multiple arterial grafts using BITA, RA and SVG. Results:There was no death reported in first 30 days post operatively. Deep sternal wound infectionoccurred in only one patient. The rate of perioperative stroke and renal failure was zero. Two(2.46%) patients had acute MI and 1 patient was reopened due to bleeding. Conclusion: Weconclude that early outcome of OPCAB total or multiple arterial coronary revascularizations, inexperienced hands, are as safe and effective as ONCAB.

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MASUDA, Takatoshi, und Toshio NAGASHIMA. „165 Nonlinear stress analysis using VCAD Framework“. Proceedings of The Computational Mechanics Conference 2006.19 (2006): 583–84. http://dx.doi.org/10.1299/jsmecmd.2006.19.583.

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Arroyave Hurtado, Juan Pablo, Johny Andrey Villada Zapata und Milton Eduardo Bermúdez Jaimes. „Variabilidad y cambio en la comprensión de deseos en niños preescolares: un estudio microgenético“. Universitas Psychologica 20 (15.12.2021): 1–14. http://dx.doi.org/10.11144/javeriana.upsy20.vccd.

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Este estudio analiza la capacidad de 14 niños (35% varones) entre 2 y 3 años (M = 2.9; SD = 0.17) para comprender los deseos. La literatura ha dado por sentado que niños de esas edades comprenden deseos simples, amparándose en una postura estructuralista del desarrollo, en la que básicamente hay una descripción de hitos que están relacionados con la edad. En contraposición a esta tradición, este estudio busca dar cuenta del cambio y la variabilidad, apoyándose en la teoría de los Sistemas Dinámicos No Lineales. Por ello, usando el método microgenético, se evaluó durante varias sesiones la capacidad de los niños para usar los deseos de otros para predecir emociones y comportamientos. Se adaptaron las tareas clásicas de Wellman y Wooley (1990), y se les presentaron a los niños en 5 sesiones, en las que había 3 variaciones de las tareas. Los datos se analizaron con la técnica de mínimos y máximos, y se encontraron un conjunto de trayectorias con muchas fluctuaciones, que distan de mostrar desempeños altos y estables como lo afirman estudios previos. Se concluye que en la investigación sobre el desarrollo, las visiones acumulativas y homogéneas dificultan la observación del cambio y de la amplitud del mismo, por ello se requiere hacer hincapié en la variabilidad.

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YOKOTA, Hideo. „S203 Development of VCAD Tools for Biomedical Simulation“. Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2008.21 (2009): 341–42. http://dx.doi.org/10.1299/jsmebio.2008.21.341.

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Imai, N., T. Nagashima und K. Kase. „Crack propagation simulator V-X3D based on VCAD framework“. IOP Conference Series: Materials Science and Engineering 10 (01.06.2010): 012053. http://dx.doi.org/10.1088/1757-899x/10/1/012053.

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NISHIMURA, Masaomi, Tetsuro MURAI, Masakatsu TSUNEKI, Yutaka OTAKE, Hideo YOKOTA, Kiwamu KASE, Ryutaro HIMENO und Akitake MAKINOUTI. „523 Design of tailor made implants using VCAD system“. Proceedings of the JSME annual meeting 2006.5 (2006): 101–2. http://dx.doi.org/10.1299/jsmemecjo.2006.5.0_101.

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Ohura, K., Z. Sun, Akitake Makinouchi und Cristian Teodosiu. „Volume-CAD: An Integrated Environment for Virtual Manufacturing and Structural Analysis“. Advanced Materials Research 23 (Oktober 2007): 17–24. http://dx.doi.org/10.4028/www.scientific.net/amr.23.17.

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The Volume-CAD System Research Program aims at developing a core technology for data integration of computerized design, analysis, manufacturing, and testing processes. The potential applications of the Volume-CAD environment cover a large area of engineering and biomedical design. In this paper, we shall mainly focus on the VCAD-based software for the structural analysis and the simulation of casting processes.

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Cronin, Blaise, und Yvonne Rogers. „From Victorian visiting card to vCard: the evolution of a communicative genre“. Journal of Information Science 29, Nr. 1 (Februar 2003): 65–68. http://dx.doi.org/10.1177/016555150302900108.

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Yun, Se-Mi, und Ik-Seong Jo. „The Design and Implementation of Web Agents for vCard Service in Mobile Enviromnent“. KIPS Transactions:PartD 9D, Nr. 3 (01.06.2002): 477–86. http://dx.doi.org/10.3745/kipstd.2002.9d.3.477.

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Simoni, Laura, Alessandra Scarton, Claudio Macchi, Federico Gori, Guido Pasquini und Silvia Pogliaghi. „Quantitative and Qualitative Running Gait Analysis through an Innovative Video-Based Approach“. Sensors 21, Nr. 9 (23.04.2021): 2977. http://dx.doi.org/10.3390/s21092977.

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Quantitative and qualitative running gait analysis allows the early identification and the longitudinal monitoring of gait abnormalities linked to running-related injuries. A promising calibration- and marker-less video sensor-based technology (i.e., Graal), recently validated for walking gait, may also offer a time- and cost-efficient alternative to the gold-standard methods for running. This study aim was to ascertain the validity of an improved version of Graal for quantitative and qualitative analysis of running. In 33 healthy recreational runners (mean age 41 years), treadmill running at self-selected submaximal speed was simultaneously evaluated by a validated photosensor system (i.e., Optogait—the reference methodology) and by the video analysis of a posterior 30-fps video of the runner through the optimized version of Graal. Graal is video analysis software that provides a spectral analysis of the brightness over time for each pixel of the video, in order to identify its frequency contents. The two main frequencies of variation of the pixel’s brightness (i.e., F1 and F2) correspond to the two most important frequencies of gait (i.e., stride frequency and cadence). The Optogait system recorded step length, cadence, and its variability (vCAD, a traditional index of gait quality). Graal provided a direct measurement of F2 (reflecting cadence), an indirect measure of step length, and two indexes of global gait quality (harmony and synchrony index). The correspondence between quantitative indexes (Cadence vs. F2 and step length vs. Graal step length) was tested via paired t-test, correlations, and Bland–Altman plots. The relationship between qualitative indexes (vCAD vs. Harmony and Synchrony Index) was investigated by correlation analysis. Cadence and step length were, respectively, not significantly different from and highly correlated with F2 (1.41 Hz ± 0.09 Hz vs. 1.42 Hz ± 0.08 Hz, p = 0.25, r2 = 0.81) and Graal step length (104.70 cm ± 013.27 cm vs. 107.56 cm ± 13.67 cm, p = 0.55, r2 = 0.98). Bland–Altman tests confirmed a non-significant bias and small imprecision between methods for both parameters. The vCAD was 1.84% ± 0.66%, and it was significantly correlated with neither the Harmony nor the Synchrony Index (0.21 ± 0.03, p = 0.92, r2 = 0.00038; 0.21 ± 0.96, p = 0.87, r2 = 0.00122). These findings confirm the validity of the optimized version of Graal for the measurement of quantitative indexes of gait. Hence, Graal constitutes an extremely time- and cost-efficient tool suitable for quantitative analysis of running. However, its validity for qualitative running gait analysis remains inconclusive and will require further evaluation in a wider range of absolute and relative running intensities in different individuals.

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Michikawa, Takashi, Kiwamu Kase, Yutaka Ohtake, Zhigang Sun, Cristian Teodosiu und Akitake Makinouchi. „3113 Hexahedral Mesh Generation by VCAD and Dual Meshes for Structural Analysis“. Proceedings of Design & Systems Conference 2006.16 (2006): 282–83. http://dx.doi.org/10.1299/jsmedsd.2006.16.282.

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Cronin, B., und Y. Rogers. „Brief Communication. From Victorian visiting card to vCard: the evolution of a communicative genre“. Journal of Information Science 29, Nr. 1 (01.01.2003): 65–68. http://dx.doi.org/10.1177/016555103762202096.

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Luo, Zhi Feng, Chao Sun und Shun Xiang Wu. „Fetching Address Book Info of iPhone OS“. Advanced Materials Research 204-210 (Februar 2011): 1266–69. http://dx.doi.org/10.4028/www.scientific.net/amr.204-210.1266.

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With the rapid development of mobile technology, the mobile phones has gradually become an indispensable part in everybody’s life, and it is replacing the computer’s position step by step. The iPhone is a smart phone made of Apple Company, which opens a new era of software for mobile devices. At the same time, iOS(iPhone’s operating system) has become one of most competitive mobile communications operating systems. The Apple’s protection for security makes the iPhone owners hardly control their phone through the root (highest authority). It is so difficult to manage the information effetely with iPhone, such as contacts’ information or SMS. The paper introduced two approaches to get the contacts’ information in iPhone and restore them with vCard. At last, we managed the output file on MAC.

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Zaghouani Chakroun, Amal, und Dorra Mezzez Hmaied. „Evidence on aggregate volatility risk premium for the French stock market“. Managerial Finance 46, Nr. 1 (31.10.2019): 72–91. http://dx.doi.org/10.1108/mf-11-2018-0535.

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Purpose The purpose of this paper is to examine alternative six- and seven-factor equity pricing models directed at capturing a new factor, aggregate volatility, in addition to market, size, book to market, profitability, investment premiums of the Fama and French (2015) and Fama and French’s (2018) aggregate volatility augmented model. Design/methodology/approach The models are tested using a time series regression and Fama and Macbeth’s (1973) methodology. Findings The authors show that both six- and seven-factor models best explain average excess returns on the French stock market. In fact, the authors outperform Fama and French’s (2018) model. The authors use sensitivity of aggregate volatility of a stock VCAC as a proxy to construct the aggregate volatility risk factor. The spanning tests suggest that Fama and French’s (1993, 2015, 2018) and Carhart’s (1997) models do not explain the aggregate volatility risk factor FVCAC. The results show that the FVCAC factor earns significant αs across the different multifactor models and even after controlling for the exposure to all the other in Fama and French’s (2018) model. The asset pricing tests show that it is systematically priced. In fact, the authors find a significant and negative (positive) relation between the aggregate volatility risk factor and the excess returns in the French stock market when it is rising (falling), in addition, periods with downward market movements tend to coincide with high volatility. Originality/value The authors contribute to the related literature in several ways. First, the authors test two new empirical six- and seven-factor model and the authors compare them to Fama and French’s (2018) model. Second, the authors give new evidence about the VCAC, using it for the first time to the authors’ knowledge, to construct a volatility risk premium.

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MAKINOUCHI, Akitake. „S201 VCAD system : a base for integrating modeling and simulation of multiple processes“. Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2008.21 (2009): 337–38. http://dx.doi.org/10.1299/jsmebio.2008.21.337.

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IMAI, Noboru, Toshio NAGASHIMA und Kiwamu KASE. „1306 Implementation of crack propagation simulation to VCAD based analysis software V-X3D“. Proceedings of The Computational Mechanics Conference 2009.22 (2009): 364–65. http://dx.doi.org/10.1299/jsmecmd.2009.22.364.

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MAKINOUCHI, Akitake. „W03(1) Integration of modeling and simulation processes based on VCAD system environment“. Reference Collection of Annual Meeting 2006.8 (2006): 273–74. http://dx.doi.org/10.1299/jsmemecjsm.2006.8.0_273.

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Itani, Norihiko, Y. Watanabe, W. Lin, Y. Uehara, Shinya MORITA, T. Mishima, Hitoshi Ohmori und Akitake Makinouchi. „R&D of Ray Tracing Simulation Software and Fabrication Technologies Based on VCAD (Volume-CAD) Concept for GRIN Lens“. Key Engineering Materials 381-382 (Juni 2008): 109–12. http://dx.doi.org/10.4028/www.scientific.net/kem.381-382.109.

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We have been developing an intellectual manufacturing process applying IT (V-Cam system fabrication processes) based on Volume-CAD (VCAD) system which can express internal information of materials. This paper introduces the ultra-precision grinding, ray tracing (optical path) simulation software ‘V-Opt’ and the measurement of actual optical functions in the development of optical element taking gradient refractive index (GRIN) lens with functionally graded material properties as a model. In finish ground GRIN lens using SD#8000 wheel, the P-V (Peek to Value) of 27.07 nm, surface roughness (Ra) of 1.83 nm is obtained. ‘V-Opt’ developed for GRIN lens have two main functions; one is the visualizations of ray tracing and the other is the evaluation of spot diagram and focal length.

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KASE, Kiwamu, Takashi KANAI und Yutaka OHTAKE. „WS4-3 The outline of Volume-CAD and implicit surfaces on VCAD modeling(2)“. Proceedings of the Fluids engineering conference 2006 (2006): _WS4–3–1_—_WS4–3–4_. http://dx.doi.org/10.1299/jsmefed.2006._ws4-3-1_.

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KASE, Kiwamu, Takashi KANAI und Yutaka OHTAKE. „WS4-3 The outline of Volume-CAD and implicit surfaces on VCAD modeling(1)“. Proceedings of the Fluids engineering conference 2006 (2006): _WS4–3—a_. http://dx.doi.org/10.1299/jsmefed.2006._ws4-3-a_.

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Akbar, Mochamad Dandi, und Antoni Antoni. „Aplikasi Absensi Pegawai pada Dinas Komunikasi dan Informatika Kabupaten Deli Serdang dengan QR Code Menggunakan Algoritma Bcrypt“. sudo Jurnal Teknik Informatika 1, Nr. 1 (25.03.2022): 8–16. http://dx.doi.org/10.56211/sudo.v1i1.2.

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Pengelolaan absensi data pada kantor dinas kominfo kabupaten deli serdang ini masih secara manual dengan tanda tangan pada buku absen. Rekapitulasi kehadiran juga dilakukan secara manual yakni dengan mencatat dan menghitung jumlah pegawai yang hadir, sakit atau tanpa keterangan. Proses rekapitulasi tersebut membutuhkan ketelitian yang tinggi untuk menghindari kekeliruan dalam perhitungan jumlah kehadiran. Selain itu, kelemahan dari absensi manual tersebut dapat terjadi kecurangan yang mungkin dilakukan berupa URL, nomor telepon, pesan SMS, VCard, atau teks apapun. Penelitian ini ini dilakukan untuk mengatasi masalah tersebut dengan menggunakan teknologi QR Code berbasis web. QR Code merupakan kode yang mampu menyimpan dan memberikan data dengan respon dengan cepat. Metode yang digunakan adalah Metode Bcrypt yang berfungsi untuk mengenkripsi password agar password menjadi lebih aman dan tidak mudah dibaca oleh orang lain. Aplikasi yang digunakan adalah aplikasi berbasis web dengan jenis website yang digunakan adalah website dinamis dan dengan menggunakan bahasa pemograman yaitu PHP lalu menggunakan database sebagai tempat penyimpanan.

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Soulimane, Ghizlene, Belkacem Kouninef, Mohamed Senouci und Mohamed Djelti. „QR Codes and Mobile Technology Used in the Blended Learning Approach“. International Journal of Technology Diffusion 7, Nr. 4 (Oktober 2016): 1–13. http://dx.doi.org/10.4018/ijtd.2016100101.

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The purpose of this article is to explore the teaching processes that use Quick Response (QR) codes and mobile devices to support blended learning at the National Institute of Telecommunications and ICT (INTTIC). The satisfactory results of our previous research show that the use of mobile technology could enhance accessibility and communication in a blended learning course. In Algeria, the mobile penetration rate stands at over 111% and 21% with 3G. Since most of our students have access to mobile technology, three in five were smartphones. Using this technology would encourage students to use their phones to send questions to their teachers, listen to a podcast and snip the quick response (QR) codes. This paper introduces the implementations of QR codes, vcard and QR voice as a new tool in the Moodle platform in our institute. The QR code contains the URL of the page of one particular Moodle course and quiz are added to the bottom of Moodle. The students' satisfaction had been acknowledged as an important factor in order to estimate the effectiveness of a blended learning course.

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Malov, Igor’ F., und Oleg I. Malov. „The Cluster Analysis of Pulsar Parameters“. International Astronomical Union Colloquium 160 (1996): 57–58. http://dx.doi.org/10.1017/s0252921100041038.

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We have used the catalogue of (Taylor et al., 1993) to investigate the problem of a classification of pulsars. Five samples have been analysed by the main components method and by methods of the cluster analysis.i)15 pulsars with 14 known parameters P, Ṗ, W50,L(Malov et al., 1994),B,z,spectral indexa, frequencies of maximumVMand minimumVcin a spectrum (Malofeev et al., 1994), an angle between magnetic moment and rotation axisβ(Malov, 1994), the transformation coefficientη=L/Ė, magnetic field near the light cylinderBlcand a maximum derivative of a position angleC= (dψ/dφ)max(Malov, 1990).ii)130 objects with 10 parameters (the spectral characteristicsα,VM,VCand the parameter C were excluded from the consideration).iii)218 pulsars with 4 known parameters P, Ṗ, L andz. These parameters can be considered as independent variables.iv)89 sources with the same 4 parameters. This sample consists of two subsamples: 65 pulsars withP> 1 s and 24 ones withP< 0.1 s.v)24 pulsars withP< 0.1 s from the previous sample.

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Lutz, Thomas, Kiersten Flodman, Alyssa Copelas, Honorata Czapinska, Megumu Mabuchi, Alexey Fomenkov, Xinyi He, Matthias Bochtler und Shuang-yong Xu. „A protein architecture guided screen for modification dependent restriction endonucleases“. Nucleic Acids Research 47, Nr. 18 (03.09.2019): 9761–76. http://dx.doi.org/10.1093/nar/gkz755.

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Abstract Modification dependent restriction endonucleases (MDREs) often have separate catalytic and modification dependent domains. We systematically looked for previously uncharacterized fusion proteins featuring a PUA or DUF3427 domain and HNH or PD-(D/E)XK catalytic domain. The enzymes were clustered by similarity of their putative modification sensing domains into several groups. The TspA15I (VcaM4I, CmeDI), ScoA3IV (MsiJI, VcaCI) and YenY4I groups, all featuring a PUA superfamily domain, preferentially cleaved DNA containing 5-methylcytosine or 5-hydroxymethylcytosine. ScoA3V, also featuring a PUA superfamily domain, but of a different clade, exhibited 6-methyladenine stimulated nicking activity. With few exceptions, ORFs for PUA-superfamily domain containing endonucleases were not close to DNA methyltransferase ORFs, strongly supporting modification dependent activity of the endonucleases. DUF3427 domain containing fusion proteins had very little or no endonuclease activity, despite the presence of a putative PD-(D/E)XK catalytic domain. However, their expression potently restricted phage T4gt in Escherichia coli cells. In contrast to the ORFs for PUA domain containing endonucleases, the ORFs for DUF3427 fusion proteins were frequently found in defense islands, often also featuring DNA methyltransferases.

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Firmansyah, Fahmi, Maulida Dwi Kartikasari, Makmur Sujarwo, Teguh Budi Raharjo und Dien Noviany Rahmatika. „Peran Otoritas Jasa Keuangan Dalam Pencegahan Fintech Illegal di Masyarakat“. Permana : Jurnal Perpajakan, Manajemen, dan Akuntansi 14, Nr. 1 (28.02.2022): 168–79. http://dx.doi.org/10.24905/permana.v14i1.215.

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Technological advances have an impact on aspects of life. The emergence of technological finance in online loans makes it easy to get the desired funds in a short and easy process. There are many cases of illegal fintech that we can see in national and international media. One example is the case of the VLoan application owned by PT Vcard Technology Indonesia. The purpose of this research is to see and analyze the role of the Financial Services Authority in preventing illegal activities in society, because the rampant illegal fintech in society is certainly detrimental to several parties. This research uses qualitative research with high-performance qualitative analysis application tools, namely NVivo 12. Based on the research results, the role of the Financial Services Authority in preventing illegal fintech by means of education and socialization has been effective. Obstacles in preventing illegal fintech, namely the low level of public understanding of online loans, low levels of financial literacy. This research is also expected to be a relevant source for the future. Keyword: Finansial Teknologi Illegal, Otoritas Jasa Keuangan, Pencegahan Fraud

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이상원. „A Study on the Relationship among the International Investment Sentiment Indicators: VKOSPI, VIX, VDAX-New, and VCAC“. Korean Journal of Financial Engineering 9, Nr. 3 (September 2010): 19–37. http://dx.doi.org/10.35527/kfedoi.2010.9.3.002.

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Ohmori, H., Y. Uehara, W. Lin, Y. Watanabe, K. Katahira, T. Naruse, N. Mitsuishi und S. Ishikawa. „New ELID Grinding Technique for Desk-top Grinding System Based on VCAD Concept(Nanoprecision Elid-grinding (continued))“. Proceedings of International Conference on Leading Edge Manufacturing in 21st century : LEM21 2005.2 (2005): 703–8. http://dx.doi.org/10.1299/jsmelem.2005.2.703.

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Darma, I. Made, und Putu Jadnya. „Legal Protection of Parties in Online Credit Agreement (Peer to Peer Lending) A Case Study of PT Vcard Technology Indonesia“. PADJADJARAN Jurnal Ilmu Hukum (Journal of Law) 06, Nr. 03 (Dezember 2019): 511–32. http://dx.doi.org/10.22304/pjih.v6n3.a5.

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The development of digital economy has led people to adapt to the use of services in information-technology-based loan or peer-to-peer lending. In early 2019, the V-loan case attracted attention of many people. The case has made debtors depressed, removed from their own houses, etc. Some debtors even were fired from works. In a case, the loan provider misused debtors’ personal data in debtors’ cell phones. The loan provider created WhatsApp groups containing all debtors’ contacts, including the debtors. Then, they uploaded pornographic content. Their objective was to defame debtors. Parties involved in loan agreement should adhere rules and arrange for reasonable loan. To discuss this matter, it is necessary to review agreement based on the Law on Electronic Information and Transaction and the Regulation of Financial Services Authority number 77 of 2016. The study focused on legal protection of parties involving in P2P lending activities. The credit agreement of peer-to-peer lending is considered valid if it is based on Article 47 of the Government Regulation number 82 of 2016. Standard contract must be based on Article 20 of the Regulation of Financial Services Authority number 77 of 2016. Electronic signature is also required based on Article 41 of the Regulation. In addition, the application of information technology and electronic transactions must be carried out based on the principles of legal certainty, benefits, good faith, and the freedom of choice of technology based on Article 3 of Law Number 19 of 2016. Principles and objectives are fundamental elements of legal certainty. Therefore, organizer and the government must protect user of peer-to-peer lending.

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Darma, I. Made, und Putu Jadnya. „Legal Protection of Parties in Online Credit Agreement (Peer to Peer Lending) A Case Study of PT Vcard Technology Indonesia“. PADJADJARAN Jurnal Ilmu Hukum (Journal of Law) 06, Nr. 03 (Dezember 2019): 511–32. http://dx.doi.org/10.22304/pjih.v6n3.a5.

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The development of digital economy has led people to adapt to the use of services in information-technology-based loan or peer-to-peer lending. In early 2019, the V-loan case attracted attention of many people. The case has made debtors depressed, removed from their own houses, etc. Some debtors even were fired from works. In a case, the loan provider misused debtors’ personal data in debtors’ cell phones. The loan provider created WhatsApp groups containing all debtors’ contacts, including the debtors. Then, they uploaded pornographic content. Their objective was to defame debtors. Parties involved in loan agreement should adhere rules and arrange for reasonable loan. To discuss this matter, it is necessary to review agreement based on the Law on Electronic Information and Transaction and the Regulation of Financial Services Authority number 77 of 2016. The study focused on legal protection of parties involving in P2P lending activities. The credit agreement of peer-to-peer lending is considered valid if it is based on Article 47 of the Government Regulation number 82 of 2016. Standard contract must be based on Article 20 of the Regulation of Financial Services Authority number 77 of 2016. Electronic signature is also required based on Article 41 of the Regulation. In addition, the application of information technology and electronic transactions must be carried out based on the principles of legal certainty, benefits, good faith, and the freedom of choice of technology based on Article 3 of Law Number 19 of 2016. Principles and objectives are fundamental elements of legal certainty. Therefore, organizer and the government must protect user of peer-to-peer lending.

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Desclee, Doriane, David Sohinto und Freddy Padonou. „Sustainability Assessment and Agricultural Supply Chains Evidence-Based Multidimensional Analyses as Tools for Strategic Decision-Making—The Case of the Pineapple Supply Chain in Benin“. Sustainability 13, Nr. 4 (14.02.2021): 2060. http://dx.doi.org/10.3390/su13042060.

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Contributing to Sustainable Development Goals and Agenda 2030 is a shared objective of all institutions and people. The challenges differ according to the characteristics of every context. In developing countries, strongly dependent on the agricultural sector, agricultural supply chains are recognized as crucial for economic growth and enablers for livelihood improvement. Moreover, sustainable development issues are correlated and can meet in agricultural supply chains. For several decades, parallel to decision-makers, the research community has elaborated sustainability assessment tools. Such tools evolved to fit with actuality, but it is challenging to find decision-making support tools for sustainable development adequate in agricultural supply chains and developing countries contexts. There is a necessity to define evidence-based tools and exhaustive analytical frameworks according to sustainability multidimensionality and strategical tradeoffs necessity. The VCA4D method aims to go beyond the limits of previous methods. It proposes a combination of multidisciplinary analytical tools applied empirically to analyze agricultural supply chains in their context. It provides evidence-based analytical results allowing to identify enablers for strategic sustainable and inclusive interventions. However, to even better meet contextual exhaustiveness’s expectations and indicators’ robustness to lead to relevant interventions, we should insist on a stricter framing of contextual data collection processes.

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Jarosz, Krzysztof, Piotr Niesłony und Piotr Löschner. „The effect of changes in depth of cut and cutting speed of CNC toolpaths on turning process performance“. Archives of Mechanical Technology and Materials 38, Nr. 1 (22.08.2018): 40–44. http://dx.doi.org/10.2478/amtm-2018-0007.

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Abstract In this article, a novel approach to computer optimization of CNC toolpaths by adjustment of cutting speed vcand depth of cut apis presented. Available software works by the principle of adjusting feed rate on the basis of calculations and numerical simulation of the machining process. The authors wish to expand upon this approach by proposing toolpath optimization by altering two other basic process parameters. Intricacies and problems related totheadjustment of apand vcwere explained in the introductory part. Simulation of different variant of the same turning process with different parameter values were conducted to evaluate the effect of changes in depth of cut and cutting speed on process performance. Obtained results were investigated on the account of cutting force and tool life. The authors have found that depth of cut substantially affects cutting force, while the effect of cutting speed on it is minimal. An increase in both depth of cut and cutting speed affects tool life negatively, although the impact of cutting speed is much more severe. An increase in depth of cut allows for a more significant reduction of machining time, while affecting tool life less negatively. On the other hand, the adjustment of cutting speed helpsto reduce machining time without increasing cutting force component values and spindle load.

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Kashif, Muhammad, Muhammad Sultan und Zahid Mahmood Khan. „Alternative Air-Conditioning Options for Developing Countries“. European Journal of Engineering Research and Science 2, Nr. 1 (31.01.2017): 76. http://dx.doi.org/10.24018/ejers.2017.2.1.261.

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This study assesses the potential selection of efficient air-conditioning (AC) and cooling systems in order to avoid excess power consumption, mitigation of harmful refrigerants generated by the existing AC systems. Several varieties of active and passive air-conditioning systems i.e. heating ventilating air-conditioning (HVAC), vapor compression air-conditioning (VCAC) conventional direct evaporative cooling (DEC) and indirect evaporative cooling (IEC) and desiccant air-conditioning (DAC) systems are under practice for the cooling and dehumidification. The storage of agricultural products mainly based on product individual characteristics i.e. respiration rate, transpiration rate and moisture content of that product. Variant ambient air conditions and the type of application are the main parameters for the choice of air-conditioning system to get optimum performance. The DAC system subsidize the coefficient of performance (COP) in humid regions, coastal ranges of developing countries e.g. Karachi and Gawadar (Pakistan) with hot humid climatic conditions. In similar way, hottest regions of the country such as Sibbi, Jacobabad and Multan perform better results when incorporates with M-cycle evaporative cooling system. Variation in ambient air conditions directly affect the cooling load and the choice of sustainable air-conditioning system

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Kashif, Muhammad, Muhammad Sultan und Zahid Mahmood Khan. „Alternative Air-Conditioning Options for Developing Countries“. European Journal of Engineering and Technology Research 2, Nr. 1 (31.01.2017): 76–79. http://dx.doi.org/10.24018/ejeng.2017.2.1.261.

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This study assesses the potential selection of efficient air-conditioning (AC) and cooling systems in order to avoid excess power consumption, mitigation of harmful refrigerants generated by the existing AC systems. Several varieties of active and passive air-conditioning systems i.e. heating ventilating air-conditioning (HVAC), vapor compression air-conditioning (VCAC) conventional direct evaporative cooling (DEC) and indirect evaporative cooling (IEC) and desiccant air-conditioning (DAC) systems are under practice for the cooling and dehumidification. The storage of agricultural products mainly based on product individual characteristics i.e. respiration rate, transpiration rate and moisture content of that product. Variant ambient air conditions and the type of application are the main parameters for the choice of air-conditioning system to get optimum performance. The DAC system subsidize the coefficient of performance (COP) in humid regions, coastal ranges of developing countries e.g. Karachi and Gawadar (Pakistan) with hot humid climatic conditions. In similar way, hottest regions of the country such as Sibbi, Jacobabad and Multan perform better results when incorporates with M-cycle evaporative cooling system. Variation in ambient air conditions directly affect the cooling load and the choice of sustainable air-conditioning system

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Fukasaku, K., M. Negoro, H. Iwase, K. Yokoi und R. Himeno. „Computational Fluid Dynamics for Brain Circulation and Aneurysm with Therapeutic Devices“. Interventional Neuroradiology 10, Nr. 2_suppl (Dezember 2004): 108–12. http://dx.doi.org/10.1177/15910199040100s220.

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We analysed fluid dynamics at brain arteries having multiple inflow and out flow like Willis ring based on clinical imaging modalities. In addition, we analysed fluid dynamics with therapeutic devices like coils and stents to simulate their influences to blood flow. 3D CTA and MRA obtained three-dimensional structures of the brain vessels. The centreline was obtained from the three dimensional structure. Diameter of the blood vessels was measured by 3D CTA/MRA then smooth surfaced blood vessel models were created. For the fluid analysis, we developed a home brew software which can display parameters such as streamline, etc. In addition, our CFD (computational fluid dynamics) software can work in collaboration with a CAD (computer aided design) software which we also developed (VCAD: Volume CAD). So, therapeutic devices such as coils, balloons and stents could be placed in the models and CFD analysis could be performed placing devices in the models. The flow pattern in the complicated vascular structure could be calculated such as Willis ring which has multiple inputs like ICA, VA and multiple outlets like MCA and PCA with communicating arteries. CFD with therapeutic devices could also analysed with our system.

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Watanabe, Yutaka, Hitoshi Ohmori, Weimin Lin, Yoshihiro Uehara, Toru Suzuki, Shin-ya Morita, Nobuhide Mitsuishi und Akitake Makinouchi. „Development of Aspherical Gradient Index (GRIN) Lens Fabrication System based on VCAD Concept and ELID Grinding(Nanoprecision Elid-grinding (continued))“. Proceedings of International Conference on Leading Edge Manufacturing in 21st century : LEM21 2005.2 (2005): 697–702. http://dx.doi.org/10.1299/jsmelem.2005.2.697.

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Gittenberger-de Groot, Adriana C., Cornelia Tennstedt, Rabih Chaoui, Heleen Lie-Venema, Ursula Sauer und Robert E. Poelmann. „Ventriculo coronary arterial communications (VCAC) and myocardial sinusoids in hearts with pulmonary atresia with intact ventricular septum: two different diseases“. Progress in Pediatric Cardiology 13, Nr. 3 (Oktober 2001): 157–64. http://dx.doi.org/10.1016/s1058-9813(01)00102-3.

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Chatterjee, Shramana, Seema Nath und Udayaditya Sen. „High resolution structure of Vibrio cholerae acylphosphatase (VcAcP) cage: Identification of drugs, location of its binding site and engineering to facilitate cage formation“. Biochemical and Biophysical Research Communications 523, Nr. 2 (März 2020): 348–53. http://dx.doi.org/10.1016/j.bbrc.2019.12.060.

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Usman, Hafiz Tahir, Kashif Ali Hashmi, Mohammad Sohail Saleemi und Ammar Akhtar. „ASSOCIATION OF ST ELEVATION IN LEAD AVR WITH LEFT MAIN STEM AND TRIPLE VESSEL DISEASES IN PATIENTS WITH NON-ST ELEVATION MYOCARDIAL INFARCTION“. Pakistan Heart Journal 54, Nr. 4 (08.01.2022): 348–51. http://dx.doi.org/10.47144/phj.v54i4.2128.

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Objectives: To determine frequency of left main stem (LMS) and triple vessel coronary artery disease (3VCAD) in patients of Non-ST-elevation myocardial infarction (NSTEMI) and to compare the frequency of LMS and 3VCAD in patients with NSTEMI with or without ST elevation in lead aVR. Methodology: Total 346 patients with NSTEMI having age 30-70 years were included in this descriptive cross-sectional study. The data on demographic details was collected. All patients underwent electrocardiography (ECG) and cardiac specific troponin-I assessment. Patients were categorized as NSTEMI with or without ST-elevation in lead aVR. Coronary angiography was performed in all patients and angiographic findings were noted. Results: Mean age of patients was 51.87±10.03 years. There were 218 (63.01%) males and 128 (36.99%) female patients. 182 (52.60%) patients of NSTEMI had ST elevation in aVR. LMS disease was found in 53 (29.10%) patients with ST elevation in aVR. Sensitivity, specificity, positive predive value and negative predictive value of ST elevation in aVR for LMS disease was 62.35%, 50.57%, 29.12% and 80.49% respectively. 3 VCAD was found in 54 (29.70%) with ST elevation in aVR. Sensitivity, specificity, positive predive value and negative predictive value of ST elevation in aVR for 3VCAD was 77.14%, 53.52%, 29.67% and 90.24% respectively. Conclusion: NSTEMI patients with ST elevation in aVR may have higher chances of having LMS disease or 3VCAD. There is high negative predictive value for ST elevation in aVR to predict LMS disease or 3VCAD.

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Shin, Sungho, Seongju Lee, Changhyun Jun und Kyoobin Lee. „BattleSound: A Game Sound Benchmark for the Sound-Specific Feedback Generation in a Battle Game“. Sensors 23, Nr. 2 (10.01.2023): 770. http://dx.doi.org/10.3390/s23020770.

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A haptic sensor coupled to a gamepad or headset is frequently used to enhance the sense of immersion for game players. However, providing haptic feedback for appropriate sound effects involves specialized audio engineering techniques to identify target sounds that vary according to the game. We propose a deep learning-based method for sound event detection (SED) to determine the optimal timing of haptic feedback in extremely noisy environments. To accomplish this, we introduce the BattleSound dataset, which contains a large volume of game sound recordings of game effects and other distracting sounds, including voice chats from a PlayerUnknown’s Battlegrounds (PUBG) game. Given the highly noisy and distracting nature of war-game environments, we set the annotation interval to 0.5 s, which is significantly shorter than the existing benchmarks for SED, to increase the likelihood that the annotated label contains sound from a single source. As a baseline, we adopt mobile-sized deep learning models to perform two tasks: weapon sound event detection (WSED) and voice chat activity detection (VCAD). The accuracy of the models trained on BattleSound was greater than 90% for both tasks; thus, BattleSound enables real-time game sound recognition in noisy environments via deep learning. In addition, we demonstrated that performance degraded significantly when the annotation interval was greater than 0.5 s, indicating that the BattleSound with short annotation intervals is advantageous for SED applications that demand real-time inferences.

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Karan, Radmila, Suzana Cvjeticanin, Natasa Kovacevic-Kostic, Dejan Nikolic, Milos Velinovic, Vladimir Milicevic und Biljana Obrenovic-Kircanski. „Genetic and Environmental Dispositions for Cardiovascular Variability: A Pilot Study“. Journal of Clinical Medicine 7, Nr. 9 (23.08.2018): 232. http://dx.doi.org/10.3390/jcm7090232.

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Background: The aim of our study was to evaluate the degree of genetic homozygosity in the group of patients with coronary artery disease (CAD), as well as to evaluate morphogenetic variability in CAD patients regarding the presence of investigated risk factors (RF) compared to a control sample of individuals. Additionally, we aimed to evaluate the distribution of ABO blood type frequencies between tested samples of individuals. Methods: This study analyzed individual phenotype and morphogenetic variability of 17 homozygously-recessive characteristics (HRC), by using HRC test in a sample of 148 individuals in CAD patients group and 156 individuals in the control group. The following RF were analyzed: hypertension, diabetes mellitus, hyperlipidemia, and smoking. Results: The mean value of HRC in CAD patients is significantly higher, while variability decreases compared to the control sample (CAD patients: 4.24 ± 1.59, control sample: 3.75 ± 1.69; VCAD-patients = 37.50%, VC = 45.07%). There is a significant difference in individual variations of 17 HRC between control sample and CAD patients (χ2 = 169.144; p < 0.01), which points out to different variability for tested genes. Mean values of HRC significantly differed in CAD patients in regard to the number of RF present. A blood type (OR = 1.75) is significant predictor for CAD, while O blood type (OR = 0.43) was significantly associated with controls. Conclusion: There is a higher degree of recessive homozygosity in CAD patients versus individuals in the control sample, and the presence of significant variations in the degree of recessive homozygosity as the number of tested RF increases.

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Grayfer, Leon, Francisco De Jesús Andino und Jacques Robert. „Prominent Amphibian (Xenopus laevis) Tadpole Type III Interferon Response to the Frog Virus 3 Ranavirus“. Journal of Virology 89, Nr. 9 (25.02.2015): 5072–82. http://dx.doi.org/10.1128/jvi.00051-15.

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ABSTRACTRanaviruses (Iridoviridae) are posing an increasing threat to amphibian populations, with anuran tadpoles being particularly susceptible to these viral infections. Moreover, amphibians are the most basal phylogenetic class of vertebrates known to possess both type I and type III interferon (IFN)-mediated immunity. Moreover, little is known regarding the respective roles of the IFN mediators in amphibian antiviral defenses. Accordingly, we transcriptionally and functionally compared the amphibianXenopus laevistype I (IFN) and III (IFN-λ) IFNs in the context of infections by the ranavirus frog virus 3 (FV3).X. laevisIFN and IFN-λ displayed distinct tissue expression profiles. In contrast to our previous findings thatX. laevistadpoles exhibit delayed and modest type I IFN responses to FV3 infections compared to the responses of adults, here we report that tadpoles mount timely and robust type III IFN gene responses. Recombinant forms of these cytokines (recombinantX. laevisIFN [rXlIFN] and rXlIFN-λ) elicited antiviral gene expression in the kidney-derived A6 cell line as well as in tadpole leukocytes and tissues. However, rXlIFN-λ was less effective than rXlIFN in preventing FV3 replication in A6 cells and tadpoles and inferior at promoting tadpole survival. Intriguingly, FV3 impaired A6 cell and tadpole kidney type III IFN receptor gene expression. Furthermore, in A6 cultures rXlIFN-λ conferred equal or greater protection than rXlIFN against recombinant viruses deficient for the putative immune evasion genes, the viral caspase activation and recruitment domain (vCARD) or a truncated vIF-2α gene. Thus, in contrast to previous assumptions, tadpoles possess intact antiviral defenses reliant on type III IFNs, which are overcome by FV3 pathogens.IMPORTANCEAnuran tadpoles, including those ofXenopus laevis, are particularly susceptible to infection by ranavirus such as FV3. We investigated the respective roles ofX. laevistype I and type III interferons (IFN and IFN-λ, respectively) during FV3 infections. Notably, tadpoles mounted timely and more robust IFN-λ gene expression responses to FV3 than adults, contrasting with the poorer tadpole type I IFN responses. However, a recombinantX. laevisIFN-λ (rXlIFN-λ) conferred less protection to tadpoles and the A6 cell line than rXlIFN, which may be explained by the FV3 impairment of IFN-λ receptor gene expression. The importance of IFN-λ in tadpole anti-FV3 defenses is underlined by the critical involvement of two putative immune evasion genes in FV3 resistance to IFN- and IFN-λ-mediated responses. These findings challenge the view that tadpoles have defective antiviral immunity and suggest, rather, that their antiviral responses are predominated by IFN-λ responses, which are overcome by FV3.

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Aponte-Daza, Vaneska Cindy, Freddy Ponce Valdivia, Bismarck Pinto Tapia und Felipe Garcia. „Duelo anticipado y afrontamiento al estrés en cuidadores informales de personas de la tercera edad“. LIBERABIT. Revista Peruana de Psicología 28, Nr. 2 (31.12.2022): e621. http://dx.doi.org/10.24265/liberabit.2022.v28n2.621.

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Antecedentes: el duelo anticipado es el proceso por el que pasan algunas personas antes del fallecimiento de un ser querido o de que se confirme su muerte. Ocurre cuando varias circunstancias hacen prever que tarde o temprano un ser querido, como un familiar, una pareja o un amigo, va a morir. Objetivo: el objetivo de estudio fue conocer cuáles son las estrategias de afrontamiento al estrés y factores personales del cuidado y del cuidador que benefician o ponen en riesgo el duelo anticipado en cuidadores informales de personas de la tercera edad. Método: participaron 272 cuidadores informales. Se utilizó la Escala del Duelo en el Cuidador de Meichsner et al. (2016) y la Escala Breve de Afrontamiento al Estrés (COPE 28) de Carver (1997). Resultados: los resultados evidencian que el duelo anticipado es influenciado por el afrontamiento: el dolor emocional por el afrontamiento basado en apoyo (OR = .236), afrontamiento evasión a la emoción (OR = 3.751) y estar todo el día de cuidado (OR = 3.061). La pérdida emocional es estimada por el afrontamiento focalizado en el problema (OR = .201), cuando el cuidador es un adulto mayor (OR = .303) y por el medio tiempo de cuidado (OR = 2.029). La aceptación de la pérdida es influenciada por el afrontamiento focalizado al problema (OR = .172), afrontamiento evasión a la emoción (OR = 4.409), cuidador es adulto joven (OR = 2.361) y por el cuidado durante casi todo el día (OR = .536). Además, la pérdida absoluta se asoció con el afrontamiento focalizado en el problema (r = .249) y el afrontamiento de evasión con sustancias (r = .216). Conclusiones: este estudio logra identificar factores personales y tipos de afrontamiento al estrés que favorecen o disminuyen el duelo anticipado en el cuidador primario informal. Particularmente, la probabilidad de presentar dolor emocional aumenta de acuerdo al afrontamiento basado en el apoyo o el espiritual, pero disminuye con el afrontamiento basado en la evasión emocional y la mayor convivencia con el enfermo. Contribución de autoría VCAD: revisión bibliográfica, elaboración de la introducción, de la justificación, del planteamiento del problema, del marco teórico, selección de la población, toma de pruebas, y elaboración de resultados y conclusiones. FPV: vaciado de datos, elaboración de base de datos, análisis de datos, creación de tablas, elaboración del método, elaboración de resultados y conclusiones. BPT: profesor guía. FG: revisión del artículo y sugerencias de correcciones.

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Jiang, Bo, Xiangjun Fang, Daqi Fu, Weijie Wu, Yanchao Han, Hangjun Chen, Ruiling Liu und Haiyan Gao. „Exogenous salicylic acid regulates organic acids metabolism in postharvest blueberry fruit“. Frontiers in Plant Science 13 (17.10.2022). http://dx.doi.org/10.3389/fpls.2022.1024909.

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Fruit acidity is an essential factor affecting blueberry organoleptic quality. The organic acid content in blueberry fruit mainly contributes to fruit acidity. This study aims to evaluate the effect of exogenous salicylic acid (SA), the principal metabolite of aspirin, on the organoleptic quality and organic acid metabolism in rabbiteye blueberry (Vaccinium virgatum Ait, ‘Powderblue’) during cold storage (4 °C). Results showed that SA-treated fruit reduced fruit decay and weight loss delayed fruit softening, and decline of total soluble solids (TSS). TA and total organic acid amounts stayed the same during the late storage period in SA-treated fruit. Four kinds of organic acid components, malic acid, quinic acid, citric acid, and succinic acid, were at higher levels in fruit treated by SA as compared to control. SA enhanced the activities of PEPC, NAD-MDH, and CS to promote the synthesis of malic acid and citric acid. Meanwhile, the activities of NADP-ME, ACL, and ACO, which participated in the degradation of malic acid and citric acid, were inhibited by SA. qPCR results also showed that the expression of VcPEPC, VcNAD-MDH, and VcCS genes were upregulated. In contrast, SA downregulated the expression of VcNADP-ME, VcACL, and VcACO genes. In conclusion, SA could regulate the key genes and enzymes that participated in organic acids metabolism to maintain the freshness of blueberry during cold storage, therefore minimizing the economic loss.

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Goebel, B., C. Salomon, M. Abdulrahman, S. Richter, M. El Garhy, E. Costello, H. Lapp und P. Lauten. „Echocardiographic predictors of the effectiveness of interventional edge-to-edge repair in tricuspid valve regurgitation“. European Heart Journal 42, Supplement_1 (01.10.2021). http://dx.doi.org/10.1093/eurheartj/ehab724.083.

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Abstract Background Percutaneous tricuspid valve edge-to-edge repair (pTVR) is a promising interventional technique for patients with tricuspid regurgitation (TR), but guidance regarding patient selection and echocardiographic screening is lacking. The aim of this study was to identify echocardiographic parameters which may predict pTVR success. Methods Before and after pTVR, echocardiographic data, including 3D full-volume datasets, were obtained and quantified. Right ventricular assessments included ejection fraction (RVEF3D) and diastolic (RVVd3D) and systolic (RVVs3D) volumes. Also evaluated were: right atrial (RA) volume, effective regurgitant orifice area by PISA method (EROAPISA), vena contracta area (VCA3D) by multiplanar reconstruction from a 3D colour Doppler loop (Figure 1a), maximal diastolic tricuspid annulus area from a 3D zoom image (Figure 1b), and tricuspid tenting area. TR severity was graded according to EROAPISA and VCA3D as grade 1+ to 5+. Results Patients (n=99, age 79±6 years, 48 male) with at least moderate to severe TR undergoing pTVR were consecutively included. The patients were divided into groups according to their post-pTVR TR grade. Group 1 had TR grade ≤2+, and group 2 had TR grade ≥3+.Echocardiographic parameters before pTVR for both groups are presented in Table 1. As expected, patients with TVR ≥3+ after pTVR had significantly worse pre-intervention echocardiographic measurements of TR severity, valve dimensions, and chamber volumes. ROC curves for the prediction of TR ≤2+ (mild to moderate) after pTVR (defined as VCA3D <0.75 cm2 and EROAPISA <0.4 cm2) were drawn for different echocardiographic features (Figure 2). VCA3D by 3D colour Doppler yielded the highest area under the ROC curve followed by TV anatomy measurements (Annulus area3D, Tenting area) and right atrial volume. Conclusion A thorough evaluation of TR and valve dimensions by 3D echocardiography, particularly the evaluation of VCA3D by 3D colour Doppler, aids in the prediction of the probability of pTVR success. Funding Acknowledgement Type of funding sources: None.

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