Thematische Bibliographien / Transfusion, ARDS

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Auswahl der wissenschaftlichen Literatur zum Thema „Transfusion, ARDS“

Autor: Grafiati

Veröffentlicht am 1. Juli 2021

Zuletzt aktualisiert am 6. Februar 2022

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Zeitschriftenartikel zum Thema "Transfusion, ARDS"

Plurad, David, Howard Belzberg, Ira Schulman, Donald Green, Ali Salim, Kenji Inaba, Peter Rhee und Demetrios Demetriades. „Leukoreduction is Associated with a Decreased Incidence of Late Onset Acute Respiratory Distress Syndrome after Injury“. American Surgeon 74, Nr. 2 (Februar 2008): 117–23. http://dx.doi.org/10.1177/000313480807400205.

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Transfusions are known to be associated with Acute Respiratory Distress Syndrome (ARDS). Transfusion of leukoreduced products may be associated with a decreased incidence of late posttraumatic ARDS (late ARDS). Data from ventilated and transfused trauma patients were analyzed. Key variables in the first 48 hours of admission were studied for their associations with late ARDS and examined for changes over the 6 year study period. Late ARDS developed in 244 of the 1488 patients studied (16.4%). The incidence in patients given nonleukoreduced (NLR) product was 30.4 per cent (75/247) versus 13.6 per cent (169/1241) for patients not exposed [2.77 (2.02–3.73), P < 0.001]. Exposure to NLR products (50.9% in 2000 vs 1.9% in 2005) and incidence of ARDS (26.3% in 2000 vs 6.3% in 2005) significantly decreased. Treatment variables independently associated with late ARDS were NLR product exposure, Total Parenteral Nutrition exposure, Peak Inspiratory Pressure ≥ 30 mm Hg, fluid balance ≥ 2 liters at 48 hours, and transfusion of ≥ 10 units of any product. NLR product exposure has an association with an increased incidence of late onset posttraumatic ARDS which is independent of large volume transfusions. Leukoreduction should be routinely included in an overall treatment strategy to furthermore mitigate this complication in critically ill trauma patients.

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Chaiwat, Onuma, John D. Lang, Monica S. Vavilala, Jin Wang, Ellen J. MacKenzie, Gregory J. Jurkovich und Frederick P. Rivara. „Early Packed Red Blood Cell Transfusion and Acute Respiratory Distress Syndrome after Trauma“. Anesthesiology 110, Nr. 2 (01.02.2009): 351–60. http://dx.doi.org/10.1097/aln.0b013e3181948a97.

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Background Transfusion of packed red blood cells (PRBCs) is a risk factor for acute respiratory distress syndrome (ARDS) in trauma patients. Yet, there is a paucity of information regarding the risk of ARDS with incremental PRBCs exposure. Methods For this retrospective analysis, eligible patients from National Study on Costs and Outcomes of Trauma were included. Our main exposure was defined as units of PRBCs transfused during the first 24 h after admission. The main outcome was ARDS. Results A total of 521 (4.6%) of 14070 patients developed ARDS, and 331 patients (63.5%) who developed ARDS received PRBCs transfusion. Injury severity, thoracic injury, polytrauma, and pneumonia receiving more than 5 units of fresh frozen plasma and 6-10 units of PRBCs were independent predictors of ARDS. Patients receiving more than 5 units of PRBCs had higher risk of developing ARDS (patients who received 6-10 units: adjusted odds ratio 2.5, 95% CI 1.12-5.3; patients who received more than 10 units: odds ratio 2.6, 95% CI 1.1-6.4). Each additional unit of PRBCs transfused conferred a 6% higher risk of ARDS (adjusted odds ratio 1.06; 95% CI 1.03-1.10). Conclusions Early transfusion of PRBCs is an independent predictor of ARDS in adult trauma patients. Conservative transfusion strategies that decrease PRBC exposure by even 1 unit may be warranted to reduce the risk of ARDS in injured patients.

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Martucci, Gennaro, Giovanna Panarello, Giovanna Occhipinti, Veronica Ferrazza, Fabio Tuzzolino, Diego Bellavia, Filippo Sanfilippo et al. „Anticoagulation and Transfusions Management in Veno-Venous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: Assessment of Factors Associated With Transfusion Requirements and Mortality“. Journal of Intensive Care Medicine 34, Nr. 8 (Mai 2017): 630–39. http://dx.doi.org/10.1177/0885066617706339.

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Purpose: We describe an approach for anticoagulation and transfusions in veno-venous–extracorporeal membrane oxygenation (VV-ECMO), evaluating factors associated with higher transfusion requirements, and their impact on mortality. Methods: Observational study on consecutive adults supported with VV-ECMO for acute respiratory distress syndrome (ARDS). We targeted an activated partial thromboplastin time of 40 to 50 seconds and a hematocrit of 24% to 30%. Univariate and multiple analyses were done to evaluate factors associated with transfusion requirements and the influence of increasing transfusions on mortality during ECMO. Results: In a cohort of 82 VV-ECMO patients (PRedicting dEath for SEvere ARDS on VV-ECMO [PRESERVE] score: 4, Interquartile range [IQR]: 3-5, Respiratory Extracorporeal Membrane Oxygenation Survival Prediction [RESP] score: 2, IQR: 2-4), 76 (92.7%) patients received at least 1 unit of packed red blood cells (PRBCs) during the intensive care unit stay related to ECMO (median PRBC/d 156 mL, IQR: 93-218; median ECMO duration 14 days, IQR: 8-22). A higher requirement of PRBC transfusions was associated with pre-ECMO hematocrit, and with the following conditions during ECMO: platelet nadir, antithrombin III (ATIII), and stage 3 of acute kidney injury (all P < .05). Sixty-two (75.6%) patients survived ECMO. Pre-ECMO hospital stay, PRBC transfusion, and septic shock were associated with mortality (all P < .05). The adjusted odds ratio for each 100mL/d increase in PRBC transfusion was 1.9 (95% confidence interval [CI]: 1.1-3.2, P = .01); for the development of septic shock it was 15.4 (95% CI: 1.7-136.8, P = .01), and for each day of pre-ECMO stay it was 1.1 (95% CI: 1-1.2, P = .04). Conclusion: Implementation of a comprehensive protocol for anticoagulation and transfusions in VV-ECMO for ARDS resulted in a low PRBC requirement, and an ECMO survival comparable to data in the literature. Lower ATIII emerged as a factor associated with increased need for transfusions. Higher PRBC transfusions were associated with ECMO mortality. Further investigations are needed to better understand the right level of anticoagulation in ECMO, and the factors to take into account in order to manage personalized transfusion practice in this select setting.

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Daher, Pamela, Pedro G. Teixeira, Thomas B. Coopwood, Lawrence H. Brown, Sadia Ali, Jayson D. Aydelotte, Brent J. Ford, Adam S. Hensely und Carlos V. Brown. „Mild to Moderate to Severe: What Drives the Severity of ARDS in Trauma Patients?“ American Surgeon 84, Nr. 6 (Juni 2018): 808–12. http://dx.doi.org/10.1177/000313481808400623.

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Acute respiratory distress syndrome (ARDS) is a complex inflammatory process with multifactorial etiologies. Risk factors for its development have been extensively studied, but factors associated with worsening severity of disease, as defined by the Berlin criteria, are poorly understood. A retrospective chart and trauma registry review identified trauma patients in our surgical intensive care unit who developed ARDS, defined according to the Berlin definition, between 2010 and 2015. The primary outcome was development of mild, moderate, or severe ARDS. A logistic regression model identified risk factors associated with developing ARDS and with worsening severity of disease. Of 2704 total patients, 432 (16%) developed ARDS. Of those, 100 (23%) were categorized as mild, 176 (41%) as moderate, and 156 (36%) as severe. Two thousand two hundred and seventy-two patients who did not develop ARDS served as controls. Male gender, blunt trauma, severe head and chest injuries, and red blood cell as well as total blood product transfusions are independent risk factors associated with ARDS. Worsening severity of disease is associated with severe chest trauma and volume of plasma transfusion. Novel findings in our study include the association between plasma transfusions and specifically severe chest trauma with worsening severity of ARDS in trauma patients.

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Malouf, M., und A. R. Glanville. „Blood Transfusion Related Adult Respiratory Distress Syndrome“. Anaesthesia and Intensive Care 21, Nr. 1 (Februar 1993): 44–49. http://dx.doi.org/10.1177/0310057x9302100112.

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Adult respiratory distress syndrome (ARDS) is a rare but important complication of blood transfusion because it has a mortality rate of 50–60%. ARDS is characterised by noncardiogenic pulmonary oedema and is often associated with major trauma and/or sepsis. Clinical features include dyspnoea, tachypnoea, chills and extensive crepitations. The pathogenesis has not been elucidated completely and a number of hypotheses have been proposed. Factors which have been implicated include neutrophil sequestration and complement activation, macrophages, metabolites of the arachidonic acid cascade and cytokines, all of which contribute to the amplification of the inflammatory process. In particular, leucoagglutinins have been implicated with blood transfusions. Treatment is generally supportive as specific therapeutic strategies remain largely unproven.

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Rajasekaran, Surender, Dominic Sanfilippo, Allen Shoemaker, Scott Curtis, Sandra Zuiderveen, Akunne Ndika, Michael Stoiko und Nabil Hassan. „Respiratory Impairment after Early Red Cell Transfusion in Pediatric Patients with ALI/ARDS“. Critical Care Research and Practice 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/646473.

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Introduction. In the first 48 hours of ventilating patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), a multipronged approach including packed red blood cell (PRBC) transfusion is undertaken to maintain oxygen delivery.Hypothesis. We hypothesized children with ALI/ARDS transfused within 48 hours of initiating mechanical ventilation would have worse outcome. The course of 34 transfused patients was retrospectively compared to 45 nontransfused control patients admitted to the PICU at Helen DeVos Children’s Hospital between January 1st 2008 and December 31st 2009.Results. Mean hemoglobin (Hb) prior to transfusion was 8.2 g/dl compared to 10.1 g/dl in control. P/F ratio decreased from135.4±7.5to116.5±8.8in transfused but increased from148.0±8.0to190.4±17.8(P<0.001) in control. OI increased in the transfused from11.7±0.9to18.7±1.6but not in control. Ventilator days in the transfused were15.6±1.7versus9.5±0.6days in control (P<0.001). There was a trend towards higher rates of MODS in transfused patients; 29.4% versus 17.7%, odds ratio 1.92, 95% CI; 0.6–5.6 Fisher exactP<0.282.Conclusion. This study suggests that early transfusions of patients with ALI/ARDS were associated with increased ventilatory needs.

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Seong, Gil Myeong, Yunkyoung Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh und Jin Won Huh. „Prognosis of Acute Respiratory Distress Syndrome in Patients With Hematological Malignancies“. Journal of Intensive Care Medicine 35, Nr. 4 (17.01.2018): 364–70. http://dx.doi.org/10.1177/0885066617753566.

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Introduction: The intensive care unit (ICU) admission of patients with hematologic malignancies is gradually increasing. Life-threatening events are common, and acute respiratory distress syndrome (ARDS) is one of the most critical conditions. The aim of this study was to investigate the clinical characteristics and outcomes of ARDS in patients with hematological malignancies admitted to the ICU. Methods: A retrospective study was performed on all patients with ARDS with hematological malignancies in a single tertiary teaching hospital between 2008 and 2015. Data on the treatment of and the outcomes of ARDS were collected to determine the clinical characteristics associated with ICU mortality. Results: During the 8-year study period, among a total of 821 patients with ARDS admitted to the ICU, all 185 patients with hematological malignancies were included in the analysis. Most of the patients (88.1%) had moderate-to-severe ARDS, and the median PaO2/FiO2 ratio was 122 (interquartile range: 88-157). The overall ICU mortality rate was 57.3% (50.0% for mild, 52.0% for moderate, and 67.7% for severe ARDS). After the univariate and the multivariate logistic regressions, the factors independently associated with a higher ICU mortality were severe ARDS (odds ratio [OR]: 2.47; 95% confidence interval [CI]: 1.17-5.25), identification of carbapenem-resistant gram-negative bacteria (OR: 6.61; 95% CI: 1.31-33.41), the amount of blood product transfusion (OR: 1.25; 95% CI: 1.13-1.38), and the progressive or refractory disease (OR: 3.01; 95% CI: 1.31-6.91). Mortality was independently lower in patients who received the initial low tidal volume ventilation (OR: 0.37, 95% CI: 0.14-0.96). Conclusion: The outcome of ARDS in patients with hematological malignancies is associated with the severity of the underlying diseases, the presence of multidrug-resistance pathogens, and the amount of transfusion; however, strict application of low tidal volume ventilation may improve the outcome of these patients at the time of diagnosis.

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Panholzer, Bernd, Katrin Meckelburg, Katharina Huenges, Grischa Hoffmann, Michael von der Brelie, Nils Haake, Kevin Pilarczyk, Jochen Cremer und Assad Haneya. „Extracorporeal membrane oxygenation for acute respiratory distress syndrome in adults: an analysis of differences between survivors and non-survivors“. Perfusion 32, Nr. 6 (10.03.2017): 495–500. http://dx.doi.org/10.1177/0267659117693075.

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Objectives: Over the last decade, extracorporeal membrane oxygenation (ECMO) has become a promising option for patients with severe acute respiratory distress syndrome (ARDS). In this single-center observational cohort study, data from a patient group with severe ARDS treated with ECMO was analyzed. Methods: Data from 46 patients [median age 54 years (18 to 72), male: 65.2%] were evaluated retrospectively between January 2009 and September 2015. Results: Diagnosis leading to ARDS was pneumonia in 63.1% of the patients. The median SOFA Score was 13 (10 to 19) and the median LIS was 3.5 (2.67 to 4). The median duration of ECMO support was 12 days (1 to 86). Twenty-eight patients (60.9%) were successfully weaned from ECMO and 22 patients survived (47.8%). Non-survivors needed significantly more frequent renal replacement therapy (37.5% vs. 18.2%; p<0.01) and transfusion of red blood cell concentrates [0.4 units (0.3 to 1.2) vs. 0.9 units (0.5 to 1.6); p<0.01] during ECMO support compared to patients who survived. Conclusion: This report suggests that ECMO currently allows treatment of severe ARDS with presumed improved survival. The incidence rate of acute kidney injury and transfusion are associated with adverse outcomes.

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Masirevic, Vesna, Radoje Colovic, Marica Basic, Vitomir Rankovic, I. Palibrk und Ljiljana Ivic. „TRALI syndrome: Noncardial lung oedema after blood transfusion“. Acta chirurgica Iugoslavica 49, Nr. 1 (2002): 69–71. http://dx.doi.org/10.2298/aci0201069m.

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Definition - signs and symptoms which include dispnea, hypertension, high temperature and high productive tracheobronchial secretion. Physical findings are lung oedema in first four hours. Such patients usually require respiratory help. After adequate therapy, symptoms disappeared in 96 hours. In the beginning, TRALI used to be a part of ARDS and it were treated that way. Today, TRALI is understand like substantive group of symptoms.

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Lyons, William S. „Transfusion-Related Acute Lung Injury, Acute Lung Injury, and ARDS“. Chest 128, Nr. 1 (Juli 2005): 470–71. http://dx.doi.org/10.1378/chest.128.1.470.

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Dissertationen zum Thema "Transfusion, ARDS"

Bowlus, Emily. „Ailments of the Soul: Blood Transfusions and the Treatment of Melancholy in Seventeenth-Century England“. VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/614.

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The first animal-to-human blood transfusions performed in seventeenth-century England focused on patients suffering from mental diseases such as melancholy. Many physicians diagnosed melancholy as a disease of the body, mind, and soul in which blood played a key role. Philosophy, religion, and folklore helped formulate blood as an elusive yet powerful substance with access to immaterial mind and soul in addition to the body. English physician Richard Lower conducted these first transfusions yet recorded little about his personal theories regarding how melancholy and blood affected the body, mind, and soul. The philosophies of Lower’s colleagues, Thomas Willis and Robert Boyle, provide a new context and reasoning behind Lower’s experiments. Lower, Willis and Boyle’s combined work explains the theory of blood diseases and how blood transfusions could potentially treat mental diseases including melancholy.

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Striffler, Julia. „Transfusion von Erythrozytenkonzentraten bei Patienten mit akutem Atemnotsyndrom (ARDS)“. 2020. https://ul.qucosa.de/id/qucosa%3A75261.

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Das ARDS ist eine in der Intensivmedizin häufig diagnostizierte Erkrankung. Ebenso ist die Gabe von Erythrozytenkonzentraten eine regelmäßig durchgeführte therapeutische Intervention auf Intensivstationen - auch und gerade bei Patienten im akuten Lungenversagen. Bei diesen besteht bezüglich einer Entscheidung für oder gegen die Transfusion von Erythrozytenkonzentraten eine besondere Schwierigkeit: Einerseits zeigen zahlreiche Studien der letzten Jahrzehnte oft gravierende Nachteile oder zumindest fehlende therapeutische Vorteile durch die Gabe von Erythrozytenkonzentraten. Andererseits ist aus pathophysiologischer Sicht anzunehmen, dass bei der im Rahmen eines ARDS bestehenden Gefahr der Gewebehypoxie durch die Transfusion von Erythrozyten eine Verbesserung der Oxygenierung erzielt werden könnte. Da eine evidenzbasierte Grundlage für das richtige Transfusionsmanagement bei diesen Patienten dennoch fehlt, sahen wir die Durchführung der vorliegenden Arbeit als indiziert an, um einen Anhalt dafür zu bekommen, ob das für andere Patientenkollektive empfohlene restriktive Transfusionsmanagement auch bei Patienten mit einem ARDS sinnvoll einsetzbar ist. Wir evaluierten daher retrospektiv Daten von all denjenigen Patienten (n = 96), die zwischen 2008 und 2012 auf der interdisziplinär- operativen Intensivstation des Universitätsklinikums Leipzig mit der Hauptdiagnose eines akuten Lungenversagens behandelt wurden. Es handelte sich insgesamt um ein Kollektiv schwer kranker Patienten, bei dem die Gesamtletalität auf der Intensivstation bei 57,3 % lag. Von den eingeschlossenen Patienten litten 84,4 % an einem schweren bis sehr schweren ARDS. Bei der Untersuchung des Outcomes in Abhängigkeit von der durchschnittlichen Hämoglobinkonzentration über den gesamten intensivstationären Aufenthalt (< 8 g/dl versus ≥ 8 g/dl) ergaben sich folgende Resultate: Patienten mit einer niedrigeren durchschnittlichen Hämoglobinkonzentration (< 8 g/dl) - hatten keine höhere Letalität auf der Intensivstation, - hatten keine längere Aufenthaltsdauer auf der Intensivstation, - hatten keinen höheren Bedarf an organunterstützenden Maßnahmen und tendenziell sogar weniger Tage mit Katecholamintherapie und Dialyse, - wurden an weniger Tagen antibiotisch behandelt, - zeigten bei Vergleich der durchschnittlichen SAPS II- und SOFA-Scores keine Assoziation mit einer höheren Gesamtmorbidität und - zeigten bei Vergleich physiologischer Transfusionstrigger keine vermehrten Hinweise auf eine Oxygenierungsstörung. Gleichzeitig wurde das Outcome in Abhängigkeit von der kumulativen (< 5 versus ≥ 5 Erythrozytenkonzentrate über den gesamten Aufenthalt auf der Intensivstation) beziehungsweise der täglichen (durchschnittlich < 0,3 versus ≥ 0,3 Erythrozytenkonzentrate pro Tag) Transfusionsmenge untersucht. Hierbei ergab sich aus den vorliegenden Daten: Patienten mit einem ARDS, die kumulativ beziehungsweise täglich eine höhere Menge an Transfusionen erhielten, - hatten keine geringere Letalität, vielmehr stieg die Letalität sogar mit zunehmender täglicher „Transfusionsdosis“, - waren insgesamt nicht seltener beziehungsweise kürzer auf eine Organunterstützung oder eine antibiotische Therapie angewiesen, - zeigten insgesamt keine geringere Gesamtmorbidität bei Vergleich der durchschnittlichen SAPS II- und SOFA- Scores und - zeigten anhand der Untersuchung physiologischer Transfusionstrigger keine Hinweise auf eine verbesserte Oxygenierung. Insgesamt deuten unsere Resultate somit darauf hin, dass sich das Outcome von Patienten im akuten Lungenversagen durch eine niedrige Hämoglobinkonzentration von unter 8 g/dl nicht verschlechtert und dass gleichzeitig durch die großzügige Transfusion von Erythrozytenkonzentraten bei diesen Patienten kein therapeutischer Benefit zu erzielen ist. Die Resultate unserer Arbeit sind durch das retrospektive Design, die geringe Patientenzahl bei einem insgesamt sehr heterogenen Kollektiv sowie durch die hohe Morbidität und Letalität der eingeschlossenen Patienten nur bedingt verwertbar. Bezüglich „harter“ Outcome-Parameter wie einer Beeinflussung der Letalität konnte keine definitive Aussage getroffen werden. Zudem muss die eingeschränkte Beurteilbarkeit eines Transfusionsbedarfs anhand der als Transfusionstrigger empfohlenen Parameter beachtet werden. Durch die Kombination einer Vielzahl von untersuchten Parametern, die übereinstimmend keinen Nachteil durch eine niedrige Hämoglobinkonzentration und keinen Vorteil durch eine höhere Dosis an transfundierten Erythrozytenkonzentraten belegen, kann jedoch von einer gewissen Validität ausgegangen werden. Konsekutiv kann zumindest vorsichtig die folgende Aussage formuliert werden: Ein restriktives Transfusionsmanagement ist auch im akuten Lungenversagen wahrscheinlich sicher. Falls demgegenüber in Ermangelung valider Forschungsdaten gegenwärtig bei Patienten im akuten Lungenversagen aus pathophysiologischen Überlegungen und ohne evidenzbasierte Grundlage fälschlicherweise zu liberal transfundiert wird, muss nicht nur von einer Gefährdung der Patienten, sondern auch von einer relevanten Ressourcenverschwendung ausgegangen werden. Nach unserer Auffassung sind daher multizentrische randomisiert-kontrollierte Studien, die ein restriktives mit einem liberalen Transfusionsmanagement an einem ausreichend großen Kollektiv von Patienten im akuten Lungenversagen vergleichen, dringend indiziert. Nach Möglichkeit wäre dabei angesichts der Hinweise darauf, dass der Transfusionsbedarf individualisiert betrachtet werden sollte, eine Differenzierung von Patienten nach Alter, Komorbiditäten, Schwere der Hypoxämie sowie gegebenenfalls weiteren Faktoren sinnvoll.

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Bücher zum Thema "Transfusion, ARDS"

Shaefi, Shahzad, und Aaron Mittel. Disruption of Diffusion. Herausgegeben von Matthew D. McEvoy und Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0019.

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Acute respiratory distress syndrome (ARDS), transfusion-related acute lung injury (TRALI), and transfusion-associated circulatory overload (TACO) are common conditions in critically ill patients that lead to pulmonary edema and hypoxemia. The nonhydrostatic edema characteristic of ARDS and TRALI is caused by an intense inflammatory response leading to increased microvascular permeability and alveolar injury. TACO is an acute hydrostatic edema temporally associated with events that precipitate lung injury. Lung-protective ventilation is the mainstay of therapy for ARDS and TRALI; optimizing gas exchange is the goal for all three. Prompt recognition is an important skill for perioperative practitioners.

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The Northern Ireland Blood Transfusion Service (Special Agency) (Establishment and Constitution) Order (Northern Ireland) 1994 (Statutory Rule: 1994: 175). Stationery Office Books, 1994.

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Britain, Great. Health and Personal Social Services: The Northern Ireland Blood Transfusion Service (Special Agency) (Establishment and Constitution) Order (Northern Ireland) 1994. Belfast: HMSO, 1994.

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Buchteile zum Thema "Transfusion, ARDS"

Belsher, J., H. Khan und O. Gajic. „Transfusion as a Risk Factor for ALI and ARDS“. In Yearbook of Intensive Care and Emergency Medicine, 289–96. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-33396-7_27.

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Rosenow, Edward C. „Community-Acquired Acute Respiratory Distress Syndrome (ARDS)“. In Mayo Clinic Challenging Images for Pulmonary Board Review, 18–21. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199756926.003.0003.

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An otherwise healthy person without a known predisposing pulmonary condition presents to the emergency department with acute onset of respiratory distress • Noncardiac pulmonary edema ∘ Neurogenic pulmonary edema ∘ High-altitude pulmonary edema ∘ Near drowning ∘ Anaphylaxis ∘ Aspiration ∘ Transfusion-related acute lung injury (when blood products are given on an outpatient basis)...

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Little, Brent P., und Travis S. Henry. „Acute Respiratory Distress Syndrome“. In Chest Imaging, 77–82. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780199858064.003.0014.

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Adult respiratory distress syndrome (ARDS) is a clinical diagnosis of diffuse lung injury leading to severe hypoxemia in spite of high inspired oxygen concentrations. Histologically, ARDS manifests as diffuse alveolar damage (DAD). Intrapulmonary causes of ARDS include pneumonia, inhalational injuries, aspiration, and chest trauma. Extrapulmonary or systemic causes include sepsis, multi-organ failure, transfusion reaction, pancreatitis, and drug toxicity. The early exudative phase occurs within 72 hours of the precipitating cause, and usually manifests with diffuse bilateral airspace opacities. The organizing phase occurs later, with a dependent gradient of consolidation worse in the posterior lower lungs; bronchial dilatation may develop rapidly. In survivors, the lung may return to a relatively normal state, or may develop fibrosis. Fibrosis is often more severe in the anterior portions of the lungs due to the protective effect of the typically posterior, dependent consolidation and atelectasis of ARDS. Imaging findings of ARDS may appear in patients with progressive dyspnea and tachypnea who require mechanical ventilation. Pneumothorax may occur in patients with ARDS due to barotrauma, with minimal loss of volume of the ipsilateral lung due to its increased density and decreased compliance

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Apaydin, Tuba. „The Role of Mınımally Invasive Surgery in Management of Chest Trauma“. In Trauma and Emergency Surgery [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98439.

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The role of minimal invasive surgery in management of chest trauma should not be underestimated. The amount of data for video-assisted thoracoscopic surgery (VATS) management in chest-trauma patient is rare. Nevertheless the on-going acceptance and use of VATS for major thoracic resections has led to advanced techniques for management of major bleedings in the elective-surgery-patient. VATS as a procedure for pleural space management in the non-critical, non-massive-transfusion patients can be of great assistance. Its value in persistent non-major-vessel-bleeding hemothorax in terms of pleural space debridement is unchallenged. In some cases VATS is considered to be related to lower ARDS-rates in comparison to open thoracotomy patients, whereby an obvious bias for the non-massive-injury-patients exist. Jin et al. could prove a significant advantage for stable thoracic trauma patients treated through VATS in a randomised trial vs. open thoracotomy.

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Miranda, Miguel. „Inspiração e transfusão“. In Medicina e Outras Artes: Fernando Namora no Centenário do seu Nascimento, 103–13. FLUP-ILC, 2020. http://dx.doi.org/10.21747/978-9895478422/lib23a8.

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In this essay, we consider the experience of a doctor/ writer, thinking through the ways in which literature and medicine complement each other for an enhanced perception of human beings. The humanist dimension of Medicine is thus stressed, despite the technological and bureaucratic paraphernalia of current medical activity. Several answers are suggested for many of the questions that such topic raises: what makes doctors write? What do they write about? Where does their inspiration come from? In the end, an irrefutable conclusion is reached: Medicine and Literature are two of the most beautiful arts in the world.

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Konferenzberichte zum Thema "Transfusion, ARDS"

Grynovska, Marta, Volodymyr Protas und Ivan Titov. „Utility of NIV in management of transfusion-related ARDS“. In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2160.

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Pulsipher, A. M., E. H. Pratt, A. Brucker, C. Green, D. Bonadonna und C. Rackley. „Hemoglobin Transfusion Thresholds in Patients on VV-ECMO for ARDS“. In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2673.

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Benson, AB, G. Austin, C. Silliman und M. Moss. „Transfusion Associated Acute Respiratory Distress Syndrome (ARDS) in Patients with Gastrointestinal Bleeding: Effect of End Stage Liver Disease and the Use of Fresh Frozen Plasma.“ In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4639.

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