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Brunt, Kelly M., Thomas A. Neumann, Jason M. Amundson, Jeffrey L. Kavanaugh, Mahsa S. Moussavi, Kaitlin M. Walsh, William B. Cook und Thorsten Markus. „MABEL photon-counting laser altimetry data in Alaska for ICESat-2 simulations and development“. Cryosphere 10, Nr. 4 (10.08.2016): 1707–19. http://dx.doi.org/10.5194/tc-10-1707-2016.
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Abstract. Ice, Cloud, and land Elevation Satellite-2 (ICESat-2) is scheduled to launch in late 2017 and will carry the Advanced Topographic Laser Altimeter System (ATLAS), which is a photon-counting laser altimeter and represents a new approach to satellite determination of surface elevation. Given the new technology of ATLAS, an airborne instrument, the Multiple Altimeter Beam Experimental Lidar (MABEL), was developed to provide data needed for satellite-algorithm development and ICESat-2 error analysis. MABEL was deployed out of Fairbanks, Alaska, in July 2014 to provide a test dataset for algorithm development in summer conditions with water-saturated snow and ice surfaces. Here we compare MABEL lidar data to in situ observations in Southeast Alaska to assess instrument performance in summer conditions and in the presence of glacier surface melt ponds and a wet snowpack. Results indicate the following: (1) based on MABEL and in situ data comparisons, the ATLAS 90 m beam-spacing strategy will provide a valid assessment of across-track slope that is consistent with shallow slopes (< 1°) of an ice-sheet interior over 50 to 150 m length scales; (2) the dense along-track sampling strategy of photon counting systems can provide crevasse detail; and (3) MABEL 532 nm wavelength light may sample both the surface and subsurface of shallow (approximately 2 m deep) supraglacial melt ponds. The data associated with crevasses and melt ponds indicate the potential ICESat-2 will have for the study of mountain and other small glaciers.
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Fischer, Lucy. „Screen Test“. Feminist Media Histories 2, Nr. 4 (2016): 15–63. http://dx.doi.org/10.1525/fmh.2016.2.4.15.
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The Hollywood star system developed in the early decades of the twentieth century, and with it came notions of celebrity and tales of how performers rose to fame. In the same period, several American films self-reflexively devised narratives concerning young women venturing to “filmland” to break into the movies—echoing the real-life situation of the epoch's “movie-struck girls.” Taking a gendered approach, this text examines Mabel's Dramatic Career (1913), A Girl's Folly (1917), The Extra Girl (1923), Souls for Sale (1923), Ella Cinders (1926), and Show People (1928), interrogating the films’ portrayal of the female ingenue and focusing on such dichotomies as talent versus luck, career versus marriage, scandal versus propriety, city versus country, beauty versus plainness, and more. It investigates movie magazines and press of the era, highlighting how they presented the actresses in these films—Mabel Normand, Marion Davies, Eleanor Boardman, Colleen Moore, and Doris Kenyon—to the public, making connections to similar issues in the movies.
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Mukaromah, Siti, Khusna Widhyahrini und Norwanto Norwanto. „Aplikasi Si Marbel Sebagai Alternatif Media Pembelajaran Tematik di Pendidikan Dasar“. Jurnal Pemikiran dan Pengembangan Sekolah Dasar (JP2SD) 8, Nr. 2 (21.09.2020): 138–47. http://dx.doi.org/10.22219/jp2sd.v8i2.13005.
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Penelitian ini bertujuan untuk melakukan analisis kebutuhan untuk mengembangkan aplikasi permainan edukatif Si Marbel sebagai media pembelajaran tematik di kelas 1 Sekolah Dasar (SD); mengembangkan dan menguji penerapan aplikasi pendidikan Si Marbel sebagai media pembelajaran tematik di kelas 1; dan mengetahui efektivitas aplikasi permainan edukatif Si Marbel sebagai media pembelajaran tematik di kelas 1 SD. Penelitian ini menggunakan metode pengembangan atau Research and Development (R&D) dan aplikasi Si Marbel adalah produk penelitian ini. Model penelitian yang digunakan adalah model desain instruksional ADDIE (Analysis-Design-Develop-Implement-Evaluate).. Hasil dari penelitian ini adalah berupa pengembangan aplikasi permainan edukatif Si Marbel. Hasil penilaian pakar media masing-masing adalah 90 dan 93. Rata-rata adalah 91,5 yang menunjukkan bahwa pengembangan aplikasi pendidikan Si Marbel valid dan dapat diterapkan untuk pembelajaran di kelas 1 MI Negeri Salatiga. (3) Uji efektifitas menunjukkan signifikansi (2-tailed) adalah 0.000 (p < 0,05). Hasil pre-test dan post-test menunjukkan perubahan yang signifikan. Statistik deskriptif dari nilai-nilai pre-test dan post-test menunjukkan bahwa skor post-test lebih baik. Oleh karena itu, aplikasi permainan edukatif Si Marbel terbukti efektif digunakan dalam pembelajaran tematik tema 5 "Pengalamanku"
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Kumari, Minal, Yogesh Kumar und Parvinder Kaur. „Effectiveness of Module Based Learning regarding Facility Based Newborn Care in terms of knowledge and practices among nursing students“. International Journal of Contemporary Pediatrics 6, Nr. 5 (23.08.2019): 2184. http://dx.doi.org/10.18203/2349-3291.ijcp20193749.
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ABSTRACTBackground: Mobile Applications are being developed at a rapid speed and are intensively used by students. It can help to achieve better performance in organizing, managing, and monitoring classroom activities.Aims and objectives: Present study aimedto assess and compare the knowledge and practice regarding FBNC among nursing students in MBL group and MABL group before and after the administration of MBL and MABL. The conceptual framework of the study was based on CIPP model by Stufflebeam.Methods: A Quantitative research approach with quasi-experimental and non-equivalent controlgroup pre–test post–test design. The study was conducted at two nursing colleges of Ambala, Haryana. A total of 70 B.Sc. Nursing 3rd Year students, randomly allocated to 2 groups i.e. 35 in MBL and 35 in MABL. The tool used for the study consisted of structured knowledge questionnaire and observational check list was used to assess knowledge and practices by OSCE method of nursing students regarding FBNC. Data collection was done in January, 2017. The obtained data was analyzed and interpreted in terms of objectives and researchResults: Findingsof the study indicate that revealed that mean post- test knowledge and practices score in MBL group (21.4 ±0.89) and in MABL group (22.4 ± 0.54) was significantly higher than pre-test knowledge score in MBL group (14.6±15.0) and in MABL group (16.2±17.0). Also, the mean post-test practice score in MBL group (38.1±1.91) and in MABL group (38.9± 1.20) was significantly higher than pre-test practicescore in MBL (20.4 ± 3.70) as well as in MABL group (20.5 ± 4.26). Mild positive significant relationship (r=0.03) was found between post test score of knowledge and practicesConclusion: MABL was more effective in developing the practices of nursing students regarding FBNC than MBL.
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Wise, Sarah. „Introducing MABL: A New Social Innovations Programme at the University of Melbourne“. Children Australia 41, Nr. 4 (29.11.2016): 305–7. http://dx.doi.org/10.1017/cha.2016.33.
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The purpose of this paper is to familiarise readers with a new social innovations programme at the University of Melbourne. MABL is an abbreviation for Mobilising change Alliance for Better Lives. The paper outlines the rationale for establishing MABL and describes the processes and principles it uses to generate, design, test and scale novel solutions to improve the safety and wellbeing of vulnerable children and adolescents. Information on how to join the change Alliance and/or invest in solving a better lives challenge is provided.
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Chakrabarti, Parthasarathi, und Uttam Bandyopadhyay. „A Semi-Parametric Test for Umbrella Ordering of Binary Response Probabilities at Unknown Peak“. Calcutta Statistical Association Bulletin 70, Nr. 1 (Mai 2018): 7–16. http://dx.doi.org/10.1177/0008068318767276.
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The Terpstra and Magel 1 multiple comparison test (referred to as the [Formula: see text] test) for umbrella alternative at unknown peak occasionally identifies false concavity in the population means. This work provides a semi-parametric test for umbrella ordering of chances of good health (free from disease) with unknown peak in a [Formula: see text] prospective study. The proposed test, a modified version of the [Formula: see text] test, determines true concavity in chances of good health more powerfully and shows low power against false concavity as compared to that of the [Formula: see text] test.
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Bintang, Aisyah Surya, Arif Wibowo und Tri Harjaka. „KERAGAMAN GENETIK Metarhizium anisopliae DAN VIRULENSINYA PADA LARVA KUMBANG BADAK (Oryctes rhinoceros) (GENETIC DIVERSITY of Metarhizium anisopliae AND VIRULENCE TOWARD LARVAE OF RHINOCEROS BEETLE (Oryctes rhinoceros))“. Jurnal Perlindungan Tanaman Indonesia 19, Nr. 1 (16.11.2016): 12. http://dx.doi.org/10.22146/jpti.16015.
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Rhinoceros beetle (Oryctes rhinoceros) is one of the important pests of coconut tree. One of eco-friendly control applied for this pest is by using entomopathogenic fungiMetarhizium anisopliae. There is not much information about the variability and virulence ofM. anisopliae toward O. rhinoceros. M. anisopliae isolates obtained from Biological Control Laboratory, Faculty of Agriculture, Universitas Gadjah Mada were cultured on PDA medium.M. anisopliae isolates was isolated from O. rhinoceros larvae (MaOr), Lepidiota stigma larvae (MaLs), Brontispa longissima beetle (MaBl).O. rhinoceros beetles were obtained from Kulon Progo, DIY. This study used molecular test, and virulence test toward 3rd stadium of O. rhinoceros larvae by using dipping method. Molecular test by sequence and phylogenetic analysis, showed that MaOr was located at different group (out group) with MaLs and MaBr. On the density 107 conidium/ml MaOr and MaLs were more virulent than MaBl towards 3rd stadium of O. rhinoceros larvae.Keywords: genetic diversity, Metarhizium anisopliae, Oryctes rhinoceros, virulenceKumbang badak (Oryctes rhinoceros) merupakan salah satu hama penting pada tanaman kelapa. Salah satu upaya pengendalian yang ramah lingkungan adalah dengan menggunakan jamur entomopatogen, yakni Metarhizium anisopliae. Belum banyak diketahui mengenai keragaman dan juga virulensi dari M. anisopliae terhadap O. rhinoceros. Tujuan dari penelitian ini adalah untuk mengetahui keragaman genetik M. anisopliae dan virulensinya pada larvakumbang badak. Isolat yang digunakan berasal dari Laboratorium Pengendalian Hayati, Fakultas Pertanian, Universitas Gadjah Mada dalam bentuk kultur murni pada medium PDA. Isolat yang gunakan diisolasi dari larvaOryctes rhinoceros (MaOr), larva Lepidiota stigma (MaLs), dan kumbang Brontispa longissima (MaBl). Serangga yang diuji berasal dari daerah Kulon Progo, DIY. Pengujian secara molekuler dengan analisis sekuensing dan filogenetik, menunjukkan bahwa isolat MaOr terletak pada grup yang berbeda dengan MaLs dan MaBl berdasarkan pada urutan basa DNA. Pada kerapatan 107 konidium/ml isolat MaOr dan MaLs lebih virulen terhadap larva O. rhinoceros instar 3 dibandingkan dengan MaBl.Kata kunci: keragaman genetik, Metarhizium anisopliae, Oryctes rhinoceros, virulensi
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Lee, Eunjeong, Jung-Hoon Kim, Ki-Young Heo und Yang-Ki Cho. „Advection Fog over the Eastern Yellow Sea: WRF Simulation and Its Verification by Satellite and In Situ Observations“. Remote Sensing 13, Nr. 8 (12.04.2021): 1480. http://dx.doi.org/10.3390/rs13081480.
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An observed sea fog event over the Eastern Yellow Sea on 15–16 April 2012 was reproduced in the Weather Research and Forecasting (WRF) simulation with high-resolution to investigate the roles of physical processes and synoptic-scale flows on advection fog with phase transition. First, it was verified by a satellite-based fog detection algorithm and in situ observation data. In the simulation, longwave (infrared) radiative cooling (LRC) with a downward turbulent sensible heat flux (SHF), due to the turbulence after sunset, triggered cloud formation over the surface when warm-moist air advection occurred. At night, warm air advection with continuous cooling due to longwave radiation and SHF near the surface modulated the change of the SHF from downward to upward, resulting in a drastic increase in the turbulent latent heat flux (LHF) that provided sufficient moisture at the lower atmosphere (self-moistening). This condition represents a transition from cold-sea fog to warm-sea fog. Enhanced turbulent mixing driven by a buoyancy force increased the depth of the sea fog and the marine atmospheric boundary layer (MABL) height, even at nighttime. In addition, cold air advection with a prevailing northerly wind at the top of the MABL led to a drastic increase in turbulent mixing and the MABL height and rapid growth of the height of sea fog. After sunrise, shortwave radiative warming in the fog layers offsetting the LRC near the surface weakened thermal instability, which contributed to the reduction in the MABL height, even during the daytime. In addition, dry advection of the northerly wind induced dissipation of the fog via evaporation. An additional sensitivity test of sea surface salinity showed weaker and shallower sea fog than the control due to the decrease in both the LHF and local self-moistening. Detailed findings from the simulated fog event can help to provide better guidance for fog detection using remote sensing.
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Kartini, Kartini. „Story As a Media for Improving Students' Learning Outcomes in Indonesian Class IV SD Negeri Dukuhlo 01, Bulakamba Sub-District, Brebes Regency“. Social, Humanities, and Educational Studies (SHEs): Conference Series 3, Nr. 4 (30.12.2020): 914. http://dx.doi.org/10.20961/shes.v3i4.54504.
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<p><em>The purpose of this study is to improve students' learning outcomes in Mapel Bahasa Indonesia Elementary School grade IV with fairytale media. The research conducted is class Action Research ( PTK) as many as three cycles, with each cycle consists of two meetings. The stages of each cycle are planning, implementation, observation and reflection. Each meeting is conducted pre test and post test to know the development of students. In cycle I students who completed after doing post tests by 60 % . In cycle II students completed after post-test by 80%. In cycle III students who completed after doing post tests by 90%. These results show that the medium of learning fairy tales in Indonesian subjects can improve the learning outcomes of grade 4 students at SD Negeri Dukuhlo 01 Bulakamba Subdistrict, Brebes.</em></p>
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KAMIYA, Hiroshi, Kiyoshi MAKINO und Koji ISHIYAMA. „The Test of Sound and Light for Utilization of Underground Rocky Cave(Kamaishi Mine Mable Hall).“ Journal of the Japan Society of Engineering Geology 35, Nr. 1 (1994): 31–35. http://dx.doi.org/10.5110/jjseg.35.31.
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Baldassi, Carlo, Simone Cerreia-Vioglio, Fabio Maccheroni, Massimo Marinacci und Marco Pirazzini. „A Behavioral Characterization of the Drift Diffusion Model and Its Multialternative Extension for Choice Under Time Pressure“. Management Science 66, Nr. 11 (November 2020): 5075–93. http://dx.doi.org/10.1287/mnsc.2019.3475.
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In this paper, we provide an axiomatic foundation for the value-based version of the drift diffusion model (DDM) of Ratcliff, a successful model that describes two-alternative speeded decisions between consumer goods. Our axioms present a test for model misspecification and connect the externally observable properties of choice with an important neurophysiologic account of how choice is internally implemented. We then extend our axiomatic analysis to multialternative choice under time pressure. In a nutshell, we show that binary DDM comparisons of the alternatives, paired with Markovian exploration of the consideration set, approximately lead to softmaximization. This paper was accepted by Manel Baucells, decision analysis.
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Sesara Ariyana, I. Komang. „Analisis Kesalahan Mahasiswa PGSD pada Tugas Aljabar Sederhana Mata Kuliah Konsep Dasar Mapel Matematika SD“. Cetta: Jurnal Ilmu Pendidikan 3, Nr. 2 (25.06.2020): 173–83. http://dx.doi.org/10.37329/cetta.v3i2.448.
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This study aimed to identify the errors of PGSD students on simple algebra assignments on Basic Concept of Elementary Mathematics Subject at STAHN Mpu Kuturan Singaraja. The subjects of this study were Semester II PGSD students of STAHN Mpu Kuturan Singaraja in the academic year 2019/2020 as many as 11 people. Errors in mathematics in this study were divided into factual errors, procedural errors, and conceptual errors. This type of research was a quantitative descriptive study. The data collection method used was a test. The test instrument used was a concept understanding test to be able to find students' errors. A total of 20 items in the test were validated by two experts with the Lawshe’s CVR technique. The results showed that (1) the general error rate of PGSD study program students on Simple Algebra assignment on Basic Concept of Elementary Mathematics Subject was 30.26% in the low error category, (2) there was the highest error of 43% (error category moderate) and lowest 16% (very low error category), 3) factual errors ranged from 10% - 20% (very low category), 4) procedural errors ranged from 7% - 53% (very low category to medium category), and 5) conceptual errors ranged from 35% - 65% (low to high categories).
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Permatasari, Iseu Synthia, Nana Hendracipta und Aan Subhan Pamungkas. „PENGEMBANGAN MEDIA PEMBELAJARAN VIDEO ANIMASI HANDS MOVE DENGAN KONTEKS LINGKUNGAN PADA MAPEL IPS“. Terampil : Jurnal Pendidikan dan Pembelajaran Dasar 6, Nr. 1 (08.08.2019): 34–48. http://dx.doi.org/10.24042/terampil.v6i1.4100.
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AbstrakPenelitian ini bertujuan untuk mengembangkan media pembelajaran berupa video animasi hands move dengan menggunakan aplikasi videoscribe dan camtasia studio 8 pada materi kegiatan ekonomi berdasarkan potensi alam, untuk mengetahui tingkat validitas media pembelajaran video animasi hands move yang dikembangkan, untuk mengetahui respon pengguna, serta mengukur pemahaman peserta didik. Subjek penelitian ini adalah peserta didik kelas IV SDN Kaligandu Kota Serang yang berjumlah 20 peserta didik Tahun Pelajaran 2018/2019. Hasil penelitian adalah (1) didapatkan skor rata-rata dari validasi ahli dengan presentase sebesar 86,19% yang termasuk dalam kategori “sangat layak” (2) skor rata-rata respon peserta didik dengan presentase sebesar 93,18% yang termasuk dalam kategori “sangat baik” (3) skor rata-rata respon guru dengan presentase sebesar 100% yang termasuk dalam kategori “sangat baik” (4) skor rata-rata pre-test 39,25 dengan kategori “kurang” sebelum menggunakan media video animasi hands move dan post-test sebesar 83 dengan kategori “sangat baik” setelah menggunakan media video animasi hands move yang telah mengalami peningkatan sehingga dapat disimpulkan media pembelajaran video animasi hands move dengan konteks lingkungan layak digunakan serta dapat memberikan pemahaman kepada peserta didik kelas IV pada materi kegiatan ekonomi berdasarkan potensi alam. Kata kunci : Media Pembelajaran, Video Animasi, Videoscribe, Camtasia Studio 8, Ilmu Pengetahuan Sosial AbstractThis study aims to develop learning media in the form of video animation hands move using applications videoscribe and camtasia studio 8 on economic activity material based on natural potential, to determine the validity level ofanimation video learning media hands move developed, to determine user response, and measure learners' understanding. The subjects of this study were the fourth grade students of Kaligandu Elementary School in Serang City, which numbered 20 students in the 2018/2019 Academic Year. The results of the study are (1) obtained an average score from expert validation with a percentage of 86.19% which is included in the category of "very feasible" (2) the average score of students' responses with a percentage of 93.18% which is included in the category "Very good" (3) the average score of the teacher's response with a percentage of 100% which is included in the "very good" category (4) the average score of pre-test 39.25 with the category "less" before using video animation media hands move and post-test amounting to 83 with the "very good" category after usingvideo animation media hands move that has improved so that it can be concluded that learning media animation videos hands move with an environmental context feasible to use and can provide understanding to class IV students on material economic activities based on natural potential. Keywords: Learning Media, Video Animation, Videoscribe, Camtasia Studio 8, Social Sciences
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Gravina, Marco Abdo, Cristiane Canavarro, Carlos Nelson Elias, Maria das Graças Afonso Miranda Chaves, Ione Helena Vieira Portella Brunharo und Cátia Cardoso Abdo Quintão. „Mechanical properties of NiTi and CuNiTi wires used in orthodontic treatment. Part 2: Microscopic surface appraisal and metallurgical characteristics“. Dental Press Journal of Orthodontics 19, Nr. 1 (Januar 2014): 69–76. http://dx.doi.org/10.1590/2176-9451.19.1.069-076.oar.
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OBJECTIVE: This research aimed at comparing the qualitative chemical compositions and the surface morphology of fracture regions of eight types of Nickel (Ni) Titanium (Ti) conventional wires, superelastic and heat-activated (GAC, TP, Ormco, Masel, Morelli and Unitek), to the wires with addition of copper (CuNiTi 27oC and 35oC, Ormco) after traction test. METHODS: The analyses were performed in a scanning electronic microscope (JEOL, model JSM-5800 LV) with EDS system of microanalysis (energy dispersive spectroscopy). RESULTS : The results showed that NiTi wires presented Ni and Ti as the main elements of the alloy with minimum differences in their composition. The CuNiTi wires, however, presented Ni and Ti with a significant percentage of copper (Cu). As for surface morphology, the wires that presented the lowest wire-surface roughness were the superelastic ones by Masel and Morelli, while those that presented the greatest wire-surface roughness were the CuNiTi 27oC and 35oC ones by Ormco, due to presence of microcavity formed as a result of pulling out some particles, possibly of NiTi. 4 The fracture surfaces presented characteristics of ductile fracture, with presence of microcavities. The superelastic wires by GAC and the CuNiTi 27oC and the heat-activated ones by Unitek presented the smallest microcavities and the lowest wire-surface roughness with regard to fracture, while the CuNiTi 35oC wires presented inadequate wire-surface roughness in the fracture region. CONCLUSION: CuNiTi 35oC wires did not present better morphologic characteristics in comparison to the other wires with regard to surfaces and fracture region.
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Utomo, Mulyo. „MENINGKATKAN PRESTASI BELAJAR SISWA MAPEL PRODUKTIF TEKNIK KENDARAAN RINGAN DENGAN MENGGUNAKAN MEDIA PEMBELAJARAN“. JIRA: Jurnal Inovasi dan Riset Akademik 1, Nr. 4 (11.12.2020): 319–26. http://dx.doi.org/10.47387/jira.v1i4.56.
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Tujuan dari penelitian ini adalah untuk mendapatkan data dan informasi tentang prestasi belajar serta mendapatkan bukti tentang kontribusi penggunaan media pembelajaran terhadap prestasi belajar siswa mata pelajaran Teknik Kendaraan Ringan Standar Kompetensi Pemeliharaan Sistem Starter, dari penelitian ini didapatkan data bahwa pada test akhir kegiatan pada siswa eksperimen mempunyai rata-rata prestasi belajar 78 , dan pada siswa pembanding mempunyai rata-rata prestasi belajar 73. Pada penelitian ini menggunakan metode angket dan metode dokumentasi. Adapun analisa data yang dipakai untuk pembuktian hipotesa menggunakan metode analisa data statistic dengan uji-t indepent. Dari analisis data ini diperoleh nilai t hitung sebesar 2,4 sedangkan nilai t table dengan probabilitas (α) sebesr 0,05 diperoleh nilai sebesar 2,003 dari analisa data tersebut menunjukkan t hitung t table, jadi H0 ditolak dan H1 terima sehingga dapat disimpulkan terdapat hubungan yang signifikan antara media pembelajaran dengan prestasi belajar siswa mata pelajaran Produktif Teknik Kendaraan Ringan di kompetensi Pemeliharaan Kelistrikan Kendaraan Ringan pada Standar Kompetensi Pemeliharaan Sistem Starter.The purpose of this study was to obtain data and information about learning achievement and to obtain evidence about the contribution of the use of learning media to student achievement in the subject of Light Vehicle Engineering Competency Standards for Starter System Maintenance, from this study it was obtained data that in the final test activities on experimental students had the average learning achievement was 78, and the comparison students had an average learning achievement of 73. In this study, the questionnaire method and the documentation method were used. The data analysis used to prove the hypothesis used statistical data analysis methods with independent t-test. From this data analysis, it is obtained that the t value is 2.4 while the t value with a probability (α) of 0.05 is obtained by a value of 2.003 from the data analysis, it shows t count t table, so H0 is rejected and H1 is accepted so that it can be concluded that there is a significant relationship between learning media and student achievement in the subject of Productive Light Vehicle Engineering in the Electrical Maintenance competency of Light Vehicles in the Starter System Maintenance Competency Standards.
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Fujita, Koji, Akira Oyama, Daisuke Kubo, Masahiro Kanazaki und Hiroki Nagai. „Wind Tunnel Test for Videogrammetric Deformation Measurement of UAV for Mars Airplane Balloon Experiment-1 (MABE-1)“. Journal of Flow Control, Measurement & Visualization 07, Nr. 02 (2019): 87–100. http://dx.doi.org/10.4236/jfcmv.2019.72007.
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Balligand, M., und M. H. Crigel. „Critical size defect model on the femur in rabbits“. Veterinary and Comparative Orthopaedics and Traumatology 15, Nr. 03 (2002): 158–63. http://dx.doi.org/10.1055/s-0038-1632731.
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SummaryThe study purposed to elaborate a model of non-union to test a new biomaterial enhancing bone healing in large segmental defects. The authors’ concern was to develop a model of osteosynthesis capable of maintaining the stability of a femur that sustained a segmental defect. Also, they intended to determine the length of a defect that would create a nonunion. The madel was a 20-mm segmental bone defect coupled with an appropriate osteosynthesis in the rabbit femur. Two groups of rabbits underwent a mid-shaft ostectomy. Osteosynthesis was mode by two superposed holes 2-mm cuttable plates with cerclage wires. In one group, an additional intramedullary pin was inserted. The experiment lasted 16 weeks. The rabbits of the control group suffered fracture of the plates before the end of the experiment. The rabbits of the test group showed stability of the implants and nonunion of the defect. It was concluded that a mid-shaft segmental defect of 20 mm, coupled with an osteosynthesis combining plates, wires and intramedullary pin, is a valid critical size defect model in the rabbit femur.
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Malanon, Sasatorn, Surachai Dechkunakorn, Niwat Anuwongnukroh und Wassana Wichai. „Comparison of Three Commercial Latex and Non-Latex Orthodontic Elastic Bands“. Key Engineering Materials 814 (Juli 2019): 354–59. http://dx.doi.org/10.4028/www.scientific.net/kem.814.354.
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Orthodontic elastic bands are commonly made from natural rubber because they provide high resiliency at a reasonable cost. However, hypersensitivity related to protein present in latex have been reported in some patients which has led to increased usage of non-latex elastic alternatives. Therefore, the assessment of their mechanical properties is of importance. The objective of this study was to compare the physical and mechanical properties of three commercial latex and non-latex type orthodontic elastic bands. Samples of latex and non-latex type orthodontic elastics from manufacturers – AO (6.5oz), MASEL (6.0oz), GAC (6.0oz), with 3/16-inch diameter were selected. Firstly, the physical characteristics (width, cross-sectional thickness, and inner diameter) of the elastic bands were determined, following which their mechanical properties [initial extension force (F0), 24 h-residual force (F24), percentage of force decay, force exerted at 3 times the inner diameter (F3xID) and breaking force] were tested. The data were analyzed with Mann-Whitney U test and multiple comparisons among the groups were done with Kruskal-Wallis Test (p< 0.05). Significant differences were found in the physical characteristics and mechanical properties among each brand and type of elastics. AO elastic bands had significantly low F0 and F24 compared with the others. While the percentage of force decay at 24 h was greatest in AO followed by MASEL and GAC. Non-latex type elastics showed greater force decay than latex type ones, approximately 30-40% and 20-30% of the initial force in non-latex and latex type elastic, respectively. AO elastics showed the highest F3xID and also the lowest breaking force. Overall, non-latex type elastics exhibited lower breaking force compared to latex type ones. Wide variations were observed in the physical and mechanical characteristics among same manufacturer and same elastic type. All commercial brands presented higher F3xID than that stated by the manufacturers. Non-latex type elastics showed greater force decay over 24 h than latex type ones. The differences in the properties between the 2 types of the elastics could be due to the differences in their structure and polymers composition.
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Affandi, Lutfi Adin, und Mohammad Rizan. „KEPEMIMPINAN TRANSFORMASIONAL, TRANSAKSIONAL, MOTIVASI KERJA, DAN KINERJA PERSONEL SATUAN PROVOST DETASEMEN MARKAS MABES ANGKATAN LAUT“. Jurnal Pendidikan Ekonomi dan Bisnis (JPEB) 3, Nr. 2 (21.05.2017): 44. http://dx.doi.org/10.21009/jpeb.003.2.4.
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The study aimed to investigate the effect of transformational leadership, transactional leadership and work of motivation on performance of personnel (Y) provost detachment headquarter of Indonesian Navy, either simultaneously or partialy. 59 respondent from provost detachment headquarter of Indonesian Navy, completed 71 item self-reorted measures. The data collected survey and quesionares distributed to respondent. The statistic methode used was Multiple Regression. As expected, result indicated that transformational leadership, transactional leadership and work of motivation has positive effects on performance personnel. The result show that Fcount 26.154 is greater than Ftable 2.77 at significant level 0.05 then H0 is rejected, which means that the transformational leadership (X1), transactional leadership (X2) and work of motivation (X3) together-equally significant effect on performance of personnel (Y). Partial test, all the independent variables have a value of significant alpa below 0.05 or tcount independent variables is greater than ttables thus proving the influence of transformational leadership, transactional leadership and work of motivation partially on performance personnel.
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Sarra, Merabta, Zerafa Chafia und Benlaribi Mostefa. „Y A-T-Il Une Relation Entre Teneur En Chlorophylle Et Accumulation De La Proline Chez Les Céréales À Paille Sous Déficit Hydrique?“ European Scientific Journal, ESJ 14, Nr. 15 (31.05.2018): 234. http://dx.doi.org/10.19044/esj.2018.v14n15p234.
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This paper focuses on the relationship between two genotypes of durum wheat (Triticum durum Desf.): Gamgoum Rekham (GGR) and Haurani; two genotypes of common wheat (Triticum aestivum L.): Florence aurore 8193 (FA) and Mexipak; and two genotypes of barley (Hordeum vulgare L.): Manel and Saïda 183. These genotypes were subjected to a water deficit during a period of twenty days at the heading stage. The proline content and the chlorophyll content are determined on the standard leaves both on the control and on the sample subjected to water stress after twenty days and after one and two weeks, following the return of watering. Despite the fact that these varieties are cultivated under the same conditions on the Algerian highlands, their reactions to the test conditions are very different. As a matter of fact, GGR and FA recorded very high levels of proline at the end of the stress. This, however, was at the moment when the two barley genotypes presented relatively low values for the two studied parameters. After the return of watering, the proline contents at the various genotypes returned gradually to those of the controls. The GGR genotype recovers more quickly than the others. As for the chlorophyll content, it evolves, unevenly, in the course of the test, showing no evolutionary indication in relation to the proline.
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Sanni*, Rachana R., und H. S. Guruprasad. „Hospital Management using OAM [Operation Administration & Maintenance] Tool“. International Journal of Innovative Technology and Exploring Engineering 10, Nr. 10 (30.08.2021): 24–30. http://dx.doi.org/10.35940/ijitee.j9391.08101021.
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This paper proposes a software tool to monitor the system configuration for Hospital Management System. The OAM tool monitors the system configurations after the user installs it into the system. The aim of this software is to monitor the system about its configurations and install the required softwares to the respective system. There are four tools in this application, Fintal, Piston, Naavi and Mapel. To install these, a technique of single file installation using batch scripting is used. Batch scripting is used to execute the installation files of softwares and the softwares are installed. These installation files of softwares will be embedded as execution commands in a single file called “windows batch file”, which should be saved with the extension as “.bat”. The installation that starts will be displayed in the command prompt to know whether the softwares are getting installed correctly. After each installation, the configuration and initialization of installed softwares will be displayed. The required softwares are to be installed. Each of these performs particular tasks that are required for the management of Hospitals. Fintal is used for overall management of Hospital. This is the most user-friendly part of OAM Tool. This handles overall administrative part of Hospitals. Piston is used for storing patient’s details. This stores the patients’ reports in detailed manner of each test the patient has undergone. Naavi is used for storing Laboratory details. The tests of each patient are stored here. And the last one, i.e., Mapel which is used for storing pharmaceuticals details (Medicines). It stores the details of medicines such as from which pharmaceuticals the medicines are purchased. The license of the hospital is also stored in this part of OAM Tool. All these together form an OAM Tool. This tool also manages other required softwares like, MySQL, ODBC drivers, etc. The management of Hospitals is very important as there is a need to maintain the patient details. This technique of installation is proposed in this paper to make the installation from hardware to remote installation such as, giving the access to the system in which the tool needs to be installed and to save the time of installation process.
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Abrar, Ana Nadhya. „West Papuan journalists today: An alternative human rights perspective from Indonesia“. Pacific Journalism Review : Te Koakoa 26, Nr. 1 (31.07.2020): 123–39. http://dx.doi.org/10.24135/pjr.v26i1.1075.
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This article examines the curiosity of journalists in West Papua about the notion of human rights. The selection of this theme as a focus of research can be seen as a concern for the role of journalists in the enforcement of human rights. The selection of West Papuan journalists for research departs from the position of journalists as perpetrators of journalism activities. The author has proposed four disciplines of writing news about human rights violations in West Papua: 1) the level of curiosity of the notion of human rights by West Papuan journalists; 2) the intellectual attitude of West Papuan journalists; 3) the terms of reference for practising journalism skills in writing news about human rights violations in West Papua; and 4) news about human rights violations in West Papua. To test the level of curiosity about human rights of West Papuan journalists, the author carried out indepth interviews with Benny Mawel (a journalist with tabloidjubi.com) and Arnold Belau (a journalist with suarapapua.com). The findings are discussed in terms of journalists as professionals. The author argues that that the focus on the notion of human rights in West Papua has begun to diminish.
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Berndsen, Rodrigo Strzelecki, Ricardo Jorge Klitzke, Djeison Cesar Batista, Eduardo Mauro Do Nascimento und Fabiano Ostapiv. „MECHANICAL RESISTANCE OF MOSO BAMBOO (Phyllostachys pubescens) PART 2: AXIAL TENSILE STRENGTH, HARDNESS AND WEAR RESISTANCE“. FLORESTA 44, Nr. 3 (06.03.2014): 505. http://dx.doi.org/10.5380/rf.v44i3.33311.
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AbstractBamboo is a natural resource with a wide range of applications, especially moso bamboo (Phyllostachys pubescens Mazel ex H. de Lehaie), which is one of the most used species in the world. The main objective of this work was to determine the axial tensile strength, hardness and wear resistance of moso bamboo culms planted in Paraná, Brazil. Axial tensile strength was tested by the modification of a standard designed for wood; hardness was measured by the Brinell Test method and wear resistance was assessed by the taber abraser method. Analysis of variance with a factorial arrangement was applied to verify the effect of the treatments, resulting from the combination of three ages (one, three and five years old) and three culm positions (base, middle and top), and to check a possible interaction between these factors. No significant interaction was verified between age and position for axial tensile strength and hardness, and these properties increased as the age increased and culm position rose. Moso bamboo has potential for the flooring industry because of its low mass loss in the test of wear resistance and the satisfactory hardness when compared to other bamboo species and to traditional Brazilian timber species.Keywords: Mechanical properties; age; culm position. ResumoResistência mecânica do bambu mossô (Phyllostachys pubescens) parte 2: tração paralela às fibras, dureza e desgaste abrasivo. O bambu é um recurso natural que tem amplo espectro de utilização, destacando-se o bambu mossô (Phyllostachys pubescens Mazel ex H. de Lehaie) como uma das espécies mais utilizadas no mundo. O objetivo principal do estudo foi determinar as propriedades mecânicas de resistência à tração paralela às fibras, dureza Brinell e resistência ao desgaste abrasivo de colmos do bambu mossô. A resistência à tração paralela foi determinada modificando-se uma norma específica para madeira; a dureza foi medida pelo método de Brinell e a resistência ao desgaste abrasivo foi avaliada utilizando-se o método do taber abraser. A análise de variância em arranjo fatorial foi aplicada para verificar o efeito dos tratamentos, em que foram combinadas três idades (um, três e cinco anos) e três posições nos colmos (base, meio e topo), analisando-se a possível interação entre os fatores. Não houve interação significativa entre os fatores idade e posição para a resistência à tração paralela às fibras e a dureza Brinell, observando-se que tais propriedades aumentaram com a idade e a posição longitudinal dos colmos. O bambu mossô possui potencial para a fabricação de pisos maciços, por causa da baixa perda de massa no ensaio de resistência ao desgaste abrasivo e pela dureza satisfatória em comparação com outras espécies de bambu e espécies madeireiras tradicionais.Palavras-chave: Propriedades mecânicas; idade; posição no colmo.
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V. Izquierdo, Luis A., Francyle S. H. Sanches, Francisco Molina, Rafael P. Henriques, Emerson F. Cruz und Karina M. S. Freitas. „Comparative Study of Adhesion of Brackets with Metal Injection Molding (MIM) Technology and Welded bases: In vitro Study“. Open Dentistry Journal 14, Nr. 1 (23.05.2020): 240–46. http://dx.doi.org/10.2174/1874210602014010240.
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Introduction: Brackets bonded to enamel surface depend on the adhesion material and the quality of the bracket base. Objective: The aim of this study was to compare the shear bond strength of metallic brackets with Metal Injection Molding (MIM) technology base or welded base. Materials and Methods: Forty mandibular extracted premolars mounted in acrylic resin blocks were divided randomly into two groups, both bonded with Transbond XT. In Group 1, brackets with MIM technology bases (Masel) were used, and in group 2, brackets with a welded base (Morelli) were used. After 24 hours, all brackets were tested for shear bond strength in a universal testing machine. Intergroup comparison was performed with an independent t test. Results: MIM base brackets showed a mean maximum load registered of 107.55 N, a mean shear bond strength of 9.58 MPa with a standard deviation of 5.80 MPa and the welded base brackets showed a mean maximum load of 167.37 N, a mean shear bond strength of 13.28 MPa with a standard deviation of 2.58 MPa. The difference between the two groups was statistically significant, indicating a higher shear bond strength of the welded base brackets. Conclusion: It was concluded that the brackets with welded bases presented a significantly higher shear bond strength than the brackets with MIM bases.
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Khoiroh, Ummul. „Marble Dust Exposure Relationship to Workers‘ Lung Conditions in Marble Industries“. JURNAL KESEHATAN LINGKUNGAN 12, Nr. 4 (30.10.2020): 285. http://dx.doi.org/10.20473/jkl.v12i4.2020.285-291.
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Introduction: Marbel mining in Tulungagung caused air quality pollution of dust. The level of air pollution in the marble industrial mining area in Besole village, Tulungagung, was a high category. Air pollutions from dust cause fibrosis in the lungs if continuously inhaled. This marble dust belongs to the group of differentiative dust—pulmonary disorders due to dust in the form of restriction, obstruction, or mixture of the two. The study aims to analyze the internal factors related to lung conditions in one of the Besole Village industries, Tulungagung. Method: research that has been done using cross-sectional design through a quantitative approach. Determination of the sample size by simple random sampling. Twenty-four workers consisting of 12 exposed and 12 were not exposed to dust. Result and Discussion: The results of measurements of marble dust levels in the study area were 20,000 mg/m3, which exceeds the specified threshold value. Meanwhile, the statistical test value p= 0.000 means a relationship between dust levels and the condition of workers’ lungs in the exposed area. Most workers’ lung conditions in one of the Besole village industries are quite good. Conclusion: The condition of the lungs is closely related to dust levels that exceed the threshold value. The lungs’ condition is also influenced by work time and poor behavior, namely the habit of not wearing PPE and smoking habits, causing decreased lung function.
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Budiati, Asih. „PENERAPAN PENILAIAN BERBASIS PROYEK UNTUK MENINGKATKAN KEMAMPUAN KERJA MANDIRI DAN HASIL BELAJAR MAPEL PRAKARYA MATERI PENGOLAHAN HASIL PETERNAKAN DAN PERIKANAN DI MTSN 1 BANTUL“. JIRA: Jurnal Inovasi dan Riset Akademik 1, Nr. 4 (11.12.2020): 338–49. http://dx.doi.org/10.47387/jira.v1i4.58.
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Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh penerapan penilaian berbasis proyek untuk meningkatkan kemampuan kerja mandiri dan hasil belajar mata pelajaran prakarya materi pengolahan hasil peternakan dan perikanan di MTsN 1 Bantul. Penelitian ini merupakan penelitian tindakan kelas (Classroom Action Research) yang dimaksudkan untuk mengatasi permasalahan yang ada di kelas dengan menerapkan penilaian berbasis proyek, kemudian melakukan refleksi terhadap hasil tindakan. Penelitian ini berlangsung dalam dua siklus. Setiap siklus terdiri dari tiga pertemuan, setiap siklus dilaksanakan melalui tiga tahap yaitu: tahap perencanaan, tahap pelaksanaan tindakan yang berupa pengolahan, dan tahap pelaporan yang berupa presentasi hasil pengolahan yang diakhiri dengan test . Subyek penelitian ini adalah siswa kelas IXG di MTsN 1 Bantul . Metode pengumpulan data yang digunakan adalah observasi, dokumentasi, wawancara, dan tes hasil belajar. Data yang diperoleh selama penelitian dianalisis menggunakan teknik analisis kualitatif dengan cara kategorisasi/penggolongan meliputi reduksi data, penyajian data dan pengambilan kesimpulan. Hasil penelitian menunjukkan bahwa dalam pelaksanaan pembelajaran prakarya dengan menerapkan penilaian berbasis proyek dapat meningkatkan kemampuan kerja mandiri dan hasil belajar. Hal itu ditunjukkan dengan meningkatnya kemampuan kerja mandiri siswa dari 66,5%, pada siklus I menjadi 97,25% pada siklus II. Hasil belajar siswa mengalami peningkatan dari 76,5% sebelum tindakan menjadi 77,4 pada siklus I dan menjadi 81,8 pada siklus II. Dengan demikian dapat dikatakan bahwa penerapan penilaian berbasis proyek dapat meningkatkan kemampuan kerja mandiri dan hasil belajar siswa mapel prakarya materi pengolahan hasil peternakan dan perikanan.
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Prasetyo, Wahyu Edi, Firosalia Kristin und Indri Anugraheni. „PENERAPAN MODEL PEMBELAJARAN COOPERATIVE LEARNING TIPE GROUP INVESTIGATION UNTUK MENINGKATKAN KERJASAMA DAN HASIL BELAJAR MAPEL IPA SISWA KELAS 4“. EDUKATIF : JURNAL ILMU PENDIDIKAN 1, Nr. 2 (10.06.2019): 64–71. http://dx.doi.org/10.31004/edukatif.v1i2.7.
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AbstrakTujuan penelitian ini adalah mendiskripsikan langkah-langkah model pembelajaran Kooperative Learning tipe Group Investigation dan mengetahui peningkatkan kerjasama dan hasil belajar. Penelitian ini menggunakan jenis penelitian tindakan kelas. Subjek penelitian ini adalah siswa kelas 4 SD Negeri Mangunsari 05 Salatiga dengan jumlah 40 orang. Teknik pengumpulan data dalam penelitian ini dengan mengunakan tes dan non tes, analisis data menggunakan kuantitatif dan kualitatif. Hasil dari penelitian ini menunjukan bahwa penerapan model pembelajaran pembelajaran Kooperative Learning tipe Group Investigation dapat meningkatkan kerjasama dan hasil belajar. Hal ini terbukti dengan meningkatnya data kerjasama siswa yang diperoleh melalui Penelitian yang dilaksanakan. Hal ini dapat ditunjukan melalui data kondisi awal atau disebut prasiklus siswa dengan rata-rata kerjasama siswa 17,70 dalam kategori rendah. Setelah dilaksanakan tindakan siklus I dengan model pembelajaran Kooperative learning tipe group investigation mengalami peningkatan, rata-rata kerjasama siklus I yaitu 20,72 dalam kategori cukup. Rata-rata kerjasama siklus II juga mengalami peningkatan dengan jumlah rata-rata 38,25 dan dalam kategori sangat tinggi. Untuk hasil belajar siswa juga meningkat dengan KKM yang ditentukan yaitu 70, pada tahap kondisi awal (pra siklus), rata-rata hasil belajar siswa adalah 64,50 dengan frekuensi tuntas adalah 9 siswa dengan presentase 22,50% dan frekuesi tidak tuntas 31 dengan presentase 82,50%. Pada siklus I rata-rata hasil belajar siswa meningkat sebanyak 68,50 dengan frekuensi siswa yang tuntas 19 dengan presentase 47,50% dan frekuensi siswa tidak tuntas mencapai 21 dengan presentase 52,50%. Siklus II hasil belajar kembali meningkat sebanyak 84,20 dengan frekuensi jumalah siswa yang tuntas 37 dengan presentase 92,50% dan frekuensi siswa yang tidak tuntas sebanyak 3 dengan presentase 7,50%. Kata Kunci: Kooperative Learning , Group Investigation, Kerjasama, Hasil Belajar, IPAAbstractThe purpose of this research is to decribe the steps of a learning model which is Cooperative Learning with Group Investigation type and to find out the improvement of cooperation and study result. This research is using class act type of research. The subjects of this research are 40 students from grade 4 in Mangunsari 05 Public Elementary School in Salatiga. The techniques used in collecting the data for this research was by using test and non-test, and the data analysis used were quantitative and qualitative. The result of this research shows that the application of Cooperative Learning with Group Investigation type learning model can improve cooperation and study result. This has been proven by the improvement of students’ cooperation data which was obtained through the this research. This can be showed through the data in the early condition or called as students’ pre-cycle with the students’ cooperation average of 17,70 which is included in low category. After the cycle I with the Cooperative Learning with Group Investigation type learning model was done, the data has increased, and the average in cycle 1 was 20,72 which is included in sufficient category. The cooperation average of cycle II also increased with the average number of 38,25 which is included in very high category. Students’ study result also improved, with the determined passing grade 70, on the early condition step (pre-cycle), the average of students’ study result was 64,50 along with the completion frequency of 9 students and the percentage of 22,50% and the incompletion frequency of 31 students with the percentage of 82,50%. On cycle I, the students’ study result has increased as much as 68,50 with the completion frequency of 19 students with 47,50% percentage and incompletion frequency that reached 21 students with 52,50% percentage. On cycle II, the study result increased more as much as 84,20 with the completion frequency of 37 and 92,50% percentage and incompletion frequency of 3 with 7,50% percentage.Keywords: Cooperative Learning, Group Investigation, Cooperation, Study Result, Science
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Alizamir, Saed, Francis de Véricourt und Shouqiang Wang. „Warning Against Recurring Risks: An Information Design Approach“. Management Science 66, Nr. 10 (Oktober 2020): 4612–29. http://dx.doi.org/10.1287/mnsc.2019.3420.
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The World Health Organization seeks effective ways to alert its member states about global pandemics. Motivated by this challenge, we study a public agency’s problem of designing warning policies to mitigate potential disasters that occur with advance notice. The agency privately receives early information about recurring harmful events and issues warnings to induce an uninformed stakeholder to take preemptive actions. The agency’s decision to issue a warning critically depends on its reputation, which we define as the stakeholder’s belief regarding the accuracy of the agency’s information. The agency faces then a trade-off between eliciting a proper response today and maintaining its reputation to elicit responses to future events. We formulate this problem as a dynamic Bayesian persuasion game, which we solve in closed form. We find that the agency sometimes strategically misrepresents its advance information about a current threat to cultivate its future reputation. When its reputation is sufficiently low, the agency downplays the risk and actually downplays more as its reputation improves. By contrast, when its reputation is high, the agency sometimes exaggerates the threat and exaggerates more as its reputation deteriorates. Only when its reputation is moderate does the agency send warning messages that fully disclose its private information. Our study suggests a plausible and novel rationale for some of the false alarms or omissions observed in practice. We further test the robustness of our findings to imperfect advance information, disasters without advance notice, and heterogeneous receivers. This paper was accepted by Manel Baucells, decision analysis.
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Weranti, Selly Effa. „Pengaruh Media Diorama Tiga Dimensi Terhadap Hasil Belajar Kognitif Materi Mengenal Penggunaan Uang Pada Mapel IPS Kelas III SDN Balong Bowo“. JICTE (Journal of Information and Computer Technology Education) 1, Nr. 1 (26.11.2017): 32. http://dx.doi.org/10.21070/jicte.v1i1.1186.
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Based on the results of observation in learning, teachers are still seen to dominate the teaching and learning process. Students only receive information from teachers that can cause a lack of enthusiasm so that makes the learning atmosphere that takes place looks still passive. It resulted in student learning outcomes still have not reached the maximum because of the use of media applied by teachers not in learning. This research is Quantitative research with Quasi Experimental Form Designjenis Nonequivalent control group design. The data collection technique used is the test of cognitive learning outcomes. Based on the results of data analysis obtained: 1) there is the effect of three-dimensional diorama media on the cognitive learning outcomes of the material recognize the use of money in the class III IPS SDN Balong dowo. This is proven by doing the calculation to determine the gain value of the result of unknown gain experimental class III-B with the yield of 9.09% belong to the criteria "high", meaning there is a high influence on the media diorama of three dimensions in 2 students. 90.91% entered into the criterion "medium" means there is influence "moderate" to 20 students. 2) there is a big influence of three-dimensional diorama media on student learning outcomes class III with N-gain analysis Based on the calculation obtained experimental class III-B 0,56. So in this case the influence of three-dimensional diorama media on student learning outcomes class III SDN Balong dowo moderate category because the criteria 0,56 ≤ 0.70
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Öztürk, Özden Tepeköylü, und Mümine Soytürk. „Examination of relationships between communication satisfaction and organizational identification of sport science students“. Physical Culture and Sport. Studies and Research 89, Nr. 1 (29.01.2021): 1–10. http://dx.doi.org/10.2478/pcssr-2021-0001.
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Abstract The aim of this study is to examine the predictor relationships between the satisfaction sport science students obtain from communication with lecturers and their organizational identification. Moreover, the study aims to determine whether there is a difference in both dependent variables in terms of gender, grade, whether they like their educational department, desire to change their department, establishment of out-of-class communication with lecturers, and being in active communication with lecturers in class. In this study, quantitative correlational techniques are used. Our sample comprised 252 (x¯ age = 21.39 ± 2.16) sport science students (127 female; 125 male). The “Student Communication Satisfaction Scale” developed by Goodboy, Martin, and Bolkan (2009) and adapted to Turkish by Akın, Yalnız, and Kazaz (2015) was used as a data collection tool, as was the “Organizational Identification Scale” developed by Mael and Ashforth (1992) and adapted to Turkish by Tak and Aydemir (2004). Parametric data was analyzed using Pearson correlation analysis, simple linear regression analysis, 2 × 2 MANOVA, and two-way ANOVA. Nonparametric data was analyzed using the Kruskal-Wallis H statistical test technique. The results indicate a strong and positively oriented relationship between the communication satisfaction and organizational identification of sport science students. Moreover, it is seen that communication satisfaction is a crucial predictor of organizational identification. According to our data, females’ communication satisfaction and identification levels are much higher than those of males. Students’ like or dislike of the department where they receive an education and the quality and form of communication they have established with lecturers result in significant differences in both dependent variables.
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Fiedler, Sabine. „Phraseology in Planned Languages“. Language Problems and Language Planning 23, Nr. 2 (31.12.1999): 175–87. http://dx.doi.org/10.1075/lplp.23.2.05fie.
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ZUSAMMENFASSUNG Plansprache und Phraseologie: Empirische Untersuchungen Umfassende phraseologische Untersuchungen zum Esperanto auf der Grund-lage detailierter Textanalysen, teilnehmender Beobachtungen sowie von Probandenbefragungen machen sowohl Gemeinsamkeiten als auch Unter-schiede zu Phraseologien von Ethnosprachen deutlich. Das phraseologische System des Esperanto entwickelt sich im Ergebnis sowohl bewußter als auch spontaner Faktoren. Zu den Hauptquellen der Esperanto-Phraseologie gehören Übersetzungsentlehnungen aus Ethnosprachen und das bewuBte "Planen" und Einführen von phraseologischen Einheiten. Daneben gibt es eine Gruppe von Phraseologismen, welche in besonderem MaBe die Kultur der Sprache und ihrer Sprechergemeinschaft widerspiegeln und ohne das notwendige soziokulturelle Hintergrundwissen nichtverstanden werden können. Die Analysen zeigen, daß die Phraseologie als ein wesentliches Kriterium bei der Entwicklung eines Plansprachenprojektes zur voll funk-tionierenden Sprache zu betrachten ist. RESUMO Lafrazeologio de planlingvoj: Empiriaj esploroj Ampleksa frazeologia studo pri Esperanto, realigita helpe de detalaj tekst-analizoj, partoprena observado, kaj enketoj, malkovris similajn kaj mal-similajn ecojn kompare kun etnaj aŭ naciaj lingvoj. Frazeologiaj unuoj (FUoj) jen evoluis surbaze de la kultura vivo de la komunumo, jen aperis pro konscia iniciato; la plej multnombraj montrigas konvenciigintaj au spontanaj prunto-tradukoj el naciaj lingvoj. La lingva kaj kutura fono de la lingvo-uzanto evidente influas la komprenadon, sed denaskeco ne. Konstatigis relative altaj niveloj de prilingva konscio kaj kreemo, kune kun granda gamo da sintenoj al la ekuzado de novaj FUoj.
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Sherman, Wendy, Katie Martin, Larissa Rossell, Kelly Nguyen, Pamela Grady, Cynthia Zimmermann, David Chesla und Jeffrey Mackeigan. „EPCO-24. COMPUTATIONAL APPROACH TO IDENTIFYING NEUROINFLAMMATION IN GLIOBLASTOMA MULTIFORME (GBM)“. Neuro-Oncology 22, Supplement_2 (November 2020): ii74. http://dx.doi.org/10.1093/neuonc/noaa215.303.
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Abstract INTRODUCTION Glioblastoma multiforme (GBM) is an aggressive brain cancer with dismal prognosis, despite aggressive surgery, radiation and chemotherapy. Therapies directed to the immune system are an exciting prospect in oncology and require an understanding of the interaction between tumors and immune cells. Our objective was to use computational tools to estimate immune infiltration in GBM and determine whether specific immune cell types are associated with clinical outcomes. METHODS RNA sequencing and targeted DNA sequencing (to 981 oncology genes) was performed from 37 surgically-resected GBM tumors. Tumor mutations were identified, and gene-level transcript counts were used to estimate tumor-associated cell types using bioinformatics tools. Clinical variables, including survival from surgery and diagnosis, were collected and tested for associations with molecular data. RESULTS We detected leukocyte fractions (i.e., immune infiltration) ranging from 2% to 50% in GBMs, with an average of 10.2%. Specifically, we found a statistically significant association between high Th2 cell estimates and reduced overall survival (from both surgery and diagnosis). Nine patients with high Th2 tumors had a median OS from surgery of 187 days, compared with a median of 454 days for 28 patients with low Th2 tumors (log-rank Matel-Cox test; p = 0.0023, HR = 3.1). We also found an association between NF1 mutant tumors, which were enriched for a KRAS signaling signature, and high immune infiltration (p < 0.05). CONCLUSION Our computationally-driven approach predicted significant immune infiltration in GBM and a potential association between poor prognosis and Th2 cells. The specific class of CD4+ helper T-cells is generally associated with poor anti-tumor immunity and a Th2-bias has been reported in gliomas. Our data adds to the collective understanding of the molecular landscape of GBM, as well as the complex immune environment, which will have important implications in tumor treatment and prognosis.
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Indrianie, Niken Shali. „Pengaruh Jigsaw Dan Motivasi Belajar Pada Mapel Bahasa Inggris “Reported Speech” Terhadap Hasil Belajar Siswa Kelas X SMA Taman Madya Kota Probolinggo“. JINoP (Jurnal Inovasi Pembelajaran) 1, Nr. 2 (01.12.2015): 163. http://dx.doi.org/10.22219/jinop.v1i2.2567.
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AbstractThis research is aimed to know the result of the study of the students on the English subject “Reported Speech” by using cooperative learning strategies model jigsaw in relation to the students’ motivation. This research is conducted on SMA Taman Madya, Probolinggo city by using quantitative approach. The data of the research is collected from the observation to the teacher, students’ activity, and the ability on English test “Reported Speech”. The source of the data are the students of tenth grade and observation on the school’s activity. The result of this study shows that the cooperative learning model jigsaw is well-applied in parallel to the lesson plan. The students’ activity in a group is well-conducted ad able to follow its function. The skill of the students in the learning and teaching of material and topics to the group is well-conducted and resulted in clear understanding and ability to solve the problem of English “Reported Speech” by the other students, as well as a well-conducted finishing steps and a well-established steps on doing the evaluation to show an enhanced result of study. Keywords: cooperative learning, jigsaw, learning motivation, result of study AbstrakPenelitian ini bertujuan untuk mengetahui hasil belajar siswa pada mata pelajaran bahasa Inggris “Reported Speech” dengan menggunakan pembelajaran cooperative learning model Jigsaw yang dikaitkan dengan motivasi belajar siswa . Penelitian ini dilaksanakan di SMA Taman Madya Kota Probolinggo dengan menggunakan pendekatan kuantitatif. Data penelitian berupa observasi aktivitas guru, aktivitas siswa dan kemampuan mengerjakan soal dalam bahasa Inggris “Reported Speech”. Data Penelitian bersumber pada peserta didik kelas X dan observer yang melaksanakan penelitian di sekolah tersebut. Hasil penelitian menunjukkan bahwa pembelajaran cooperative learning model Jigsaw terlaksana dengan baik sesuai dengan sintak pembelajaran yang direncanakan. Aktivitas setiap siswa yang belajar secara berkelompok dapat berperan dan dapat melaksanakan fungsinya dengan baik. Kemampuan setiap siswa dalam belajar dan mengajarkan materi/pokok bahasan kepada temannya yang lain dalam kelompok dapat berlangsung dengan baik sehingga temannya mampu untuk memahami dan memecahkan masalah bahasa Inggris “Reported Speech” dengan baik, dan pada langkah penyelesaian serta langkah mengerjakan soal evaluasi (tes) dapat terlaksana dengan baik serta menunjukkan hasil belajar yang cukup meningkat . Kata kunci: cooperative learning, jigsaw, motivasi belajar, hasil belajar
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Naumtseva, E. A., und W. A. Stroh. „Psychological Readiness for Organizational Change and its Socio-Psychological Predictors“. Social Psychology and Society 11, Nr. 4 (2020): 151–64. http://dx.doi.org/10.17759/sps.2020110411.
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Objectives. The study of socio-psychological predictors of employees’ readiness for changes (identification with the organization as a whole, identification with the unit, injective and descriptive norms) and the ratio of their contribution to the formation of employees’ readiness for changes. Background. Due to rapid technological development, the number of necessary changes within organizations is growing. A well-formed employees’ readiness for the upcoming changes is needed for the success of their implementation. It will affect the productivity of work processes. Study design. The study examined the level of readiness for organizational changes, the level of identification with the organization, with the unit, and subjective norms (injective and descriptive). Regression analysis was used to process the data. Socio-demographic characteristics differences were analyzed using the Mann—Whitney U-test and the Kruskel-Wallis N-test. Participants. The study sample included the state medical organization employees’ implementing electronic records and medical records (n = 308). Measurements. To evaluate variables, we used questionnaire “Readiness for Organizational Change” by D. Holt, questionnaire by B. Ashfort, F. Mael “Organizational Identification”, and scales for assessing perceived norms of M. Fishbein and A. Aizen. Results. It is established that identification with an organization, identification with a unit, an injective and descriptive norm are associated with a readiness to change. The strongest predictor of readiness for organizational change is the injective norm for change, the next most powerful predictor is the descriptive norm for change. A less significant contribution to readiness is identification with the organization as a whole. Identification with the working group (or unit) is associated with readiness to change negatively. The level of readiness for organizational changes among managers is significantly higher than among performers. Conclusions. Identification with the organization and unit, injective and descriptive norms make a significant contribution to the formation of employee readiness for change. Significant differences were found in the level of readiness for changes depending on the position: managers demonstrate a higher level compared to ordinary employees. The results of the study can be used by managers and management consultants to assess and build readiness for change.
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Lammek, Mateusz Jan. „Cellmates versus family – the sense of belonging among tattooed prisoners“. Psychiatria i Psychologia Kliniczna 20, Nr. 3 (30.11.2020): 159–63. http://dx.doi.org/10.15557/pipk.2020.0020.
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Introduction: The sense of belonging in a group can be a form of adaptation to the conditions of prison isolation. However, excessive group identification could result in negative consequences for the identity of an individual. The sense of support in social relations is a significant personal resource of convicts. The social identity of convicted persons influences their behaviour, and thus the effect of penitentiary interactions. Hence, the aim of the study was to assess the sense of belonging in a group among convicts with body modifications. Methods: The research was conducted in penitentiary units at the District Inspectorate of the Prison Service in Gdańsk (Poland). Fifty-eight re-sentenced convicts participated in the study (36.2% did not have body modifications, and 63.8% had tattoo/tattoos). The age of the respondents ranged from 18 to 62 years (M = 35.12; standard deviation, SD = 10.98). The participants completed the Group Identification Scale (Mael and Ashforth, 1992), the Identity Fusion Scale (Gómez et al., 2011) and the measure of identity fusion (Swann et al., 2009). Results: The study showed that convicts declare a very weak sense of belonging with their cellmates (55.2%) and a very strong sense of belonging with their family (44.8%). A relationship was observed between younger age and identity fusion; however, it was on the border of a significant statistical trend. Conclusions: Interpersonal relationships used as a personal resource in the social rehabilitation process can be extremely important for the probability of recidivism in the future. Especially, non-standard methods may allow convicts to test themselves in a new role. The self-concept should not be formatted through the prism of social stereotypes of prisoners, but with the simultaneous support of the family, which may strengthen socially acceptable behaviours.
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Nadhif, Ahmad, und Wawan Hidayat. „RIDER STRATEGY TO IMPROVE STUDENTS’ READING SKILL“. Kodifikasia 13, Nr. 2 (11.12.2019): 337. http://dx.doi.org/10.21154/kodifikasia.v13i2.1729.
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Penelitian ini bertujuan untuk mengetahui bagaimana strategy RIDER (Read, Image, Describe, Evaluate, & Repeat) diterapkan untuk meningkatkan ketrampilan membaca siswa kelas XI di MA Maarif Balong, Ponorogo. Penelitian ini adalah penelitian tindakan kelas dengan dua siklus. Criteria keberhasilan yang ditetapkan adalah bahwa 75% siswa mencapai nilai KKM Mapel Bahasa Inggris, yaitu score 68. Data diambil dengan tes (satu pre-test dan dua post-test di akhir masing-masing siklus) dan observasi kelas selama penerapan strategi. Hasil penelitian menunjukkan terdapat peningkatan yang signifikan pada prestasi siswa. Sebelum penerapan strategi, hasil pretest menunjukkan hanya ada 14,81% (4 siswa) yang mencapai nilai KKM. Hasil posttest siklus pertama menunjukkan bahwa terdapat 29,62% (8 siswa) yang mencapai KKM. Sementara itu, di posttest siklus kedua, seluruh siswa telah mencapai KKM. Demikian pula, hasil observasi menunjukkan angka partisipasi para siswa dalam proses belajar mengajar mengalami peningkatan. Di siklus pertama, hanya 33,33% yang mengajukan pertanyaan, 37,03% menjawab pertanyaan, dan 100% mencari kosakata baru. Di siklus kedua, angkanya secara berurutan menjadi 51,85%, 62,96%, dan 100%. Dengan demikian, melalui penerapan strategi RIDER, ketrampilan membaca para siswa meningkat dan demikian pula antusiasme mereka dalam belajar. [This research is aimed at finding how RIDER strategy is implemented to improve the students’ reading skill at English class at grade XI of MA Ma’arif Balong, Ponorogo. This study is a two-cycle classroom actioIn research, the success-criteria of which is that 75% of the students reach the KKM of English subject, which is score 68. The data are taken from tests (the pretest and two posttests by the end of each cycle) and classroom observation during the implementation of the RIDER strategy. The result of the tests shows significant improvement of the students’ achievement. In the pretests, which is conducted before the implementation of the strategy, only 14,81% (4 students) reach the KKM; in the posttest in the first cycle, 8 students (29,62%) reach the KKM; and lastly, in the posttest of the second cycle, all students (100%) are successful to achieve the criteria. Regarding the class participation of the students during the implementation of the strategy, the data from the observation shows as follows. In the cycle 1 the student’ activeness in asking question is 33,33%, in answering question 37,03%, in finding new vocabulary 100%. In cycle 2, the students’ activeness improves with the following details: in asking question 51,85%, in answering questions 62,96%, and in finding new vocabulary 100%. Thus, through the implementation of RIDER strategy, the students’ reading skill improves and so does their enthusiasm in learning].
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Curtis, J., F. Xie, C. S. Crowson, B. Mabey, D. Flake, R. Bamford, C. Chin et al. „FRI0553 DEVELOPMENT AND VALIDATION OF A BIOMARKER-BASED CARDIOVASCULAR RISK PREDICTION SCORE IN RHEUMATOID ARTHRITIS“. Annals of the Rheumatic Diseases 79, Suppl 1 (Juni 2020): 878–79. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2350.
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Background:Rheumatoid arthritis (RA) patients are at elevated risk for cardiovascular (CV) events, but risk stratification based on CV prediction models is not part of routine rheumatology practice.Objectives:To develop and validate a biomarker-based CV risk prediction model and compare it to alternative risk prediction models.Methods:We constructed a cohort of RA patients - age ≥40 with ≥1 RA diagnosis from a rheumatologist, excluding patients with malignancy, past myocardial infarction (MI) or stroke - by linking Medicare administrative data from 2006-2016 to multi-biomarker disease activity (MBDA) test results obtained as part of routine care. The cohort was split 2:1 to create training and internal validation datasets. The composite CV outcome was MI, stroke or CV death occurring within 3 years. Clinical predictors examined were: age, sex, race, traditional CV risk factors (e.g. diabetes, hypertension, hyperlipidemia, high-risk CV conditions [e.g. angina]), RA-related factors (e.g. glucocorticoid use, MTX, number of prior biologics), adjusted MBDA score1and its 12 biomarkers, log-transformed. Backward elimination was used to remove predictors with p ≥0.05. The resulting CV risk score was compared to four prediction models (age+sex; age+sex+CRP; age+sex+diabetes+hypertension+ smoking+high risk CV [±CRP]) in the validation dataset. We evaluated: 1) incremental improvement in the likelihood ratio test (LRT) statistic, 2) discrimination (AUROC), and 3) goodness-of-fit (predicted vs. observed, based on Kaplan-Meier estimates). Validation analyses were prespecified.Results:30,751 RA patients with 904 CV events were linked to MBDA test results and eligible for analysis. Patient characteristics were mean (SD) age 68.7 (9.5) years; 23.4% age <65; 82% women. Comorbidities included diabetes (39%), hypertension (78%), smoking (24%) and history of high-risk CV condition (37%). RA-related features included use of glucocorticoids (58%), MTX (60%), TNFi (33%) and other biologics (16%). Mean (SD) MBDA score was 41 (14). The final covariates included in the MBDA-based CV risk score were age, diabetes, hypertension, smoking, history of high-risk CV conditions, adjusted MBDA score, leptin, TNFRI and MMP-3. Median (IQR) of the predicted 3-year CV risk was 3.4% (2.1%, 5.6%). Based on extrapolation to 10-year risk, 9.4% of patients would be considered low, 10.2% borderline, 52.2% intermediate, and 28.2% high risk per 2019 ACC/AHA guidelines.Compared to four simpler CV prediction models, significant improvement in the LRT statistic was observed with the addition of the biomarker-based CV risk score (Figure 1). Model fit was good across deciles (Figure 2). The AUROC was 0.70. The MBDA-based model reclassified 28.5% of patients vs. the model based on age+sex+diabetes+hypertension +smoking+high risk CV+CRP.Figure 1.Incremental Improvement of MBDA-based CV Risk Score Compared to Other CV Risk Prediction ModelsFigure 2.MBDA-Based CV Risk Score Calibration for Composite CV Outcome at 3 YearsConclusion:A biomarker-based prediction score incorporating a few clinical risk factors appears to have good accuracy to predict CV risk in RA. Additional validation in independent cohorts will help verify its performance characteristics.References:[1] Curtis et al.,Rheumatology2018;58:874.Disclosure of Interests:Jeffrey Curtis Grant/research support from: AbbVie, Amgen, Bristol-Myers Squibb, Corrona, Janssen, Lilly, Myriad, Pfizer, Regeneron, Roche, UCB, Consultant of: AbbVie, Amgen, Bristol-Myers Squibb, Corrona, Janssen, Lilly, Myriad, Pfizer, Regeneron, Roche, UCB, Fenglong Xie: None declared, Cynthia S. Crowson Grant/research support from: Pfizer research grant, Brent Mabey Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Darl Flake Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Richard Bamford Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Cheryl Chin Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Eric Sasso Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Elena Hitraya Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Rotem Ben-Shachar Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Alexander Gutin Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Jerry Lanchbury Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc.
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Ben-Shachar, R., D. Flake, R. Bamford, B. Mabey, E. Sasso und J. Curtis. „FRI0057 A MODEL FOR QUANTIFYING THE EFFECT OF INFLAMMATION ON CARDIOVASCULAR DISEASE RISK PREDICTION IN RA PATIENTS“. Annals of the Rheumatic Diseases 79, Suppl 1 (Juni 2020): 604.2–605. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2384.
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Background:Patients with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease (CVD)[1]. Quantifying the effect of inflammation on CVD risk is important because rheumatologists can reduce inflammation with effective RA medications. A new score has been developed for predicting the risk for a CVD event (MI, stroke or CV death) in RA patients. It combines serological measures of inflammation (the multi-biomarker disease activity [MBDA] score, a measure of RA disease activity; and three individual biomarkers [TNF-RI, MMP-3 and leptin]), with age and four conventional CVD risk factors (smoking, hypertension, diabetes and history of a high- risk CVD condition)[2]. To gain insight into the potential effect that treating inflammation may have on the CVD risk score, it would be useful to know how the score is affected by the level of inflammation.Objectives:Explore the quantitative contribution of inflammation to CVD risk score in individual RA patients.Methods:To quantify the effect of inflammation on the CVD risk score across a range of MBDA scores, a commercial dataset of 177,486 RA patients with ≥2 MBDA tests between October 2010 and June 2019 was split 2:1 into training and validation datasets. Curves showing variation in the CVD risk score across the spectrum of all possible MBDA scores (1-100) were generated for canonical patient types differing in the number of conventional risk factors (0 to 4) and age (45, 55, 65, 75, 85 years). To generate these curves, the contributions of TNF-RI, MMP-3 and leptin to the CVD risk score were treated in aggregate (denoted the molecular score) and estimated using a linear regression model of the difference in molecular scores vs. the difference in MBDA scores. This model for the molecular score was fit in the training dataset, then in the full dataset, with dataset (training or validation) and the interaction between dataset and change in MBDA score included as additional predictor variables. The method was considered validated if the F-test for the interaction variable was not significant at the 0.05 level.Results:The model for estimating the molecular score from the MBDA scores was validated and shown to fit the data well (Figure 1). The estimated molecular score was applied to the CVD risk score algorithm to generate curves that show how CVD risk score varies with MBDA score for several distinct patient types. These curves demonstrate that the predicted 3-year CVD risk increases continuously and markedly with increasing level of inflammation, as represented by the MBDA score (Figure 2). Age and the number of conventional risk factors also affected the predicted CVD risk, with older patients (Figure 2a) and those with more conventional risk factors (Figure 2b) being at higher risk for a CVD event.Conclusion:The level of CVD risk predicted by a new prognostic test for RA patients depends not only on conventional risk factors, which are relatively time invariant, but also varies greatly due to inflammation, which can potentially be reduced with RA treatment.References:[1]Agca et al (2017).Ann Rheum Dis.76(1):17-28. doi: 10.1136/annrheumdis-2016-209775.[2]Curtis JR, Xie F, Crowson CS et al. (2019) ACR meeting abstract #446Disclosure of Interests:Rotem Ben-Shachar Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Darl Flake Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Richard Bamford Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Brent Mabey Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Eric Sasso Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Jeffrey Curtis Grant/research support from: AbbVie, Amgen, Bristol-Myers Squibb, Corrona, Janssen, Lilly, Myriad, Pfizer, Regeneron, Roche, UCB, Consultant of: AbbVie, Amgen, Bristol-Myers Squibb, Corrona, Janssen, Lilly, Myriad, Pfizer, Regeneron, Roche, UCB
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Curtis, J., E. Sasso, E. Hitraya, C. Chin, R. Bamford, R. Ben-Shachar, A. Gutin, D. Flake, B. Mabey und J. Lanchbury. „POS0456 EXTERNAL VALIDATION OF A MULTI-BIOMARKER-BASED CARDIOVASCULAR DISEASE RISK PREDICTION SCORE FOR RHEUMATOID ARTHRITIS PATIENTS“. Annals of the Rheumatic Diseases 80, Suppl 1 (19.05.2021): 458.2–459. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1657.
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Background:A novel score for predicting 3-year risk for CVD events in RA patients combines age, four traditional CVD risk factors (diabetes, hypertension, smoking, history of high-risk CVD event), a personalized assessment of RA-related inflammation based on the multi-biomarker disease activity (MBDA) score and, individually, 3 of its 12 biomarkers, TNF-R1, MMP-3 and leptin (log-transformed). This score was developed and internally validated using patient data from the Medicare database.Objectives:The purpose of this analysis was to externally validate the MBDA-based CVD risk prediction score in a younger cohort from the Symphony claims database.Methods:A cohort of patients greater than or equal to 18 years old with RA diagnosis from a rheumatologist and evidence of an RA-specific treatment, excluding patients with malignancy, past myocardial infarction (MI) or stroke, was created by a third party (Symphony) by matching medical and pharmaceutical claims and linking them to MBDA scores from a database of tests done for routine care. Medicare patients were excluded to avoid overlap with the internal validation cohort. Only the first MBDA test was used for each patient. The study endpoint was time from MBDA testing to first CVD event within a 3-year time horizon. CVD event was defined as MI or stroke, based on ICD-9 or ICD-10 diagnosis codes in hospital claims. Analyses focused on relative risk, not absolute risk, because CVD event data in Symphony may be incomplete. A univariate Cox proportional hazards regression model was fit with the MBDA-based CVD risk score as the sole predictor of time to CVD event to obtain a hazard ratio (HR) estimate (95% CI) and p-values from a likelihood ratio test (LRT). Sensitivity analyses determined HR for patient subgroups, with p-values determined for the interaction between subgroups and the MBDA-based CVD risk score. Using a multivariate Cox proportional hazard regression model, the MBDA-based CVD risk score was compared to a simpler model that included only age, sex, diabetes, hypertension, history of other CVD, smoking and CRP (log-transformed) for ability to predict time to a CVD event.Results:48,868 patients with 337 CVD events met eligibility criteria and had linked biomarker data. Mean age was 54.4 years. 81.7% were female (Table 1). Mean follow-up was 24.4 months. The MBDA-based CVD risk score (mean 3.3, IQR 2.8–3.8) was highly significant in univariate analysis, with HR = 3.99 (95% CI: 3.52-4.51, p = 4.4×10-95); i.e., for every 1-unit increase in risk score, the CVD event rate in this cohort was ~4 times as high. Similar results were seen in the subset of 44,379 patients <65 years old, with HR=4.26 (95% CI: 3.53-5.14, p = 1.2×10-47). In sensitivity analyses, after adjusting for multiple comparisons, there were no significant differences between HR of complementary subgroups (Figure 1). The MBDA-based CVD risk score added significant prognostic information to a simpler, clinical model (HR=2.28 [95% CI: 1.69-3.08, p = 1.6×10-7] after accounting for all other factors).Conclusion:The MBDA-based CVD risk prediction score has been externally validated in a cohort that is younger than and independent of the Medicare cohort used previously for test development and internal validation.Table 1.Cohort characteristics of RA patients with linked biomarker data and at risk for CVD events.VariableMedian (IQR) or N (%)Total patients48,868()Age, years54 (46-60)Sex, male8,940 (18.3%)Diabetes7,974 (16.3%)Hypertension19,132 (39.2%)History of high-risk CVD event6,713 (13.7%)Smoking7,487 (15.3%)CRP, mg/L4.1 (1.4-11.5)Leptin, ng/mL24.3 (10.6-47.1)MMP-3, ng/mL21.1 (14.3-36.2)TNF-RI, ng/mL1.4 (1.1-1.7)MBDA score40 (31-48)MBDA-based CVD risk score3.3 (2.8-3.8)Disclosure of Interests:Jeffrey Curtis Grant/research support from: Abbvie, Amgen, BMS, Corrona, Eli Lilly, Jannsen, Myriad Genetics, Inc., Pfizer, Regeneron, Roche, and UCB., Eric Sasso Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Autoimmune, Elena Hitraya Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Autoimmune, Cheryl Chin Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Autoimmune, Richard Bamford Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Autoimmune, Rotem Ben-Shachar Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Alexander Gutin Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Darl Flake Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Brent Mabey Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Jerry Lanchbury Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc.
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Nakamura, Akito, Keli Song, Stephen Grossman, Kristina Xega, Yuhong Zhang, Allison Berger, Allison Berger, Gary Shapiro und Dennis Huszar. „552 SUMOylation inhibitor TAK-981 activates NK cells and macrophages via Type I interferon signaling and shows synergistic activity in combination with rituximab and daratumumab in preclinical models“. Journal for ImmunoTherapy of Cancer 8, Suppl 3 (November 2020): A588. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0552.
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BackgroundTAK-981 is a first-in-class small molecule inhibitor of the SUMO activating enzyme in Phase 1 clinical trials. SUMOylation has previously been implicated in the regulation of innate immune responses and expression of Type I interferons,1 and ex vivo treatment of human and mouse immune cells with TAK-981 results in transcriptional upregulation of IFN-beta and Type I IFN receptor (IFNAR) signaling. We previously showed that TAK-981 increases NK cell activation and M1 macrophage polarization, leading to enhanced ADCC and ADCP in the presence of rituximab.2In vivo, TAK-981 induces IFNAR-dependent antitumor activity and synergizes with rituximab in xenograft-bearing mice.2 3 Here we investigated the mechanism of synergistic activity with rituximab and evaluated the combination of TAK-981 with daratumumab, another therapeutic mAb.MethodsThe role of effector function of rituximab in the mechanism of synergy with TAK-981 was evaluated in OCI-Ly10-bearing SCID mice treated with TAK-981 and the LALA-PG version of rituximab, in which mutations in the Fc region prevent FcγR binding. The combination of TAK-981 and rituximab was also evaluated in OCI-Ly10 tumor-bearing mice in which macrophages and/or NK cells were depleted with clodronate and anti-asialo GM1. TAK-981 in combination with daratumumab was evaluated in two CD38+ xenograft models, Daudi (Burkitt’s lymphoma) and LP-1 (multiple myeloma). To test ADCP activity, Daudi-KILR cells were incubated with human monocyte-derived macrophages (hMDM) treated with TAK-981 in the presence or absence of rituximab or daratumumab, with or without a neutralizing antibody to IFNAR2.ResultsUnlike rituximab, LALA-PG mutated rituximab did not synergize with TAK-981 in OCI-Ly10 tumor-bearing mice, indicating a requirement for Fc effector function. Depletion of macrophages with clodronate or NK cells with anti-asialo GM1 lessened the anti-tumor effect of the TAK-981 and rituximab combination, while dual depletion of macrophages and NK cells had a greater impact. TAK-981 showed synergistic activity in combination with daratumumab in two CD38+ xenograft models, Daudi and LP-1. In vitro, TAK-981-treated hMDM showed increased phagocytic activity against Daudi cells, and this effect was further enhanced in the presence of rituximab or daratumumab but prevented by a neutralizing antibody to IFNAR2.ConclusionsIn preclinical models, TAK-981 synergizes with rituximab through a mechanism involving Type I-IFN dependent enhancement of ADCC and ADCP, and the combination of TAK-981 with daratumumab is also synergistic.ReferencesDecque A, Joffre O, Magalhaes JG, Cossec J-C, Blecher-Gonen R, Lapaquette P, Silvin A, Manel N, Joubert P-E, Seeler J-S, Albert ML, Amit I, Amigorena S, Dejean A. Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing. Nat Immunol 2016;17:140–149.Nakamura A, Grossman S, Song K, Idamakanti N, Shaprio G, Huszar D. Inhibition of SUMOylation by TAK-981 induces antitumor innate immune responses by modulating macrophage and NK cell function through Type I IFN pathway activation [abstract]. In: Proceedings of the American Association forCancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Cancer Res 2019;79(13 Suppl):Abstract nr 1523.Huszar D. TAK-981: A first-in-class SUMOylation inhibitor in phase 1 clinical trials promotes a Type I interferon response and antitumor immunity in preclinical models. AACR Annual Meeting 2019, American Association for Cancer Research; Mar 29-Apr 03; Atlanta, GA, US. Session DDT01.
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Widiyastuti, Nia, Slameto Slameto und Elvira Hoesein Radia. „PENGEMBANGAN MEDIA PEMBELAJARAN INTERAKTIF MENGGUNAKAN SOFTWARE ADOBE FLASH MATERI BUMI DAN ALAM SEMESTA“. Perspektif Ilmu Pendidikan 32, Nr. 1 (30.04.2018): 77–84. http://dx.doi.org/10.21009/pip.321.9.
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The study aims to develop interactive learning media using Adobe Flash Professional CS6 software on Earth and Universe materials for third-grader students in primary school. The types of the study are research and development which carried out by using Borg and Gall's model development and modified into 7 development steps, which are (1) research and information collecting; (2) planning; (3) develop preliminary form of product; (4) preliminary field testing; (5) main product revision; (6) main field testing; and (7) operasional product revision. The study was conducted on April 2018 in two primary schools in Salatiga. The subjects of the study involved 10 third-grader students of primary school on preliminary field testing and 32 third-grader students of primary school on the main field testing. The results of validity test from the media expert obtained an average scores of 3,9 with a good category. The results of validity test from the material expert obtained average scores of 2.95 with good enough category. The result of students questionnaire on preliminary field testing showed the average scores of 4.5 and the result of the students questionnaire on main field testing showed the average scores of 4,6 with a very good category. Then, the result of teachers questionnaire showed an average of 5.0 on preliminary field testing and 4.8 on main field testing with a very excellent category. Based on the validation of material experts, media experts, the results of questionnaire responses of both students and teachers, interactive learning media that developed by adobe flash software of earth and the universe materials are suitable in learning for third grader of Primary School students and can enhance students’ interest in learning materials and build students’ learning motivation.
References
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Arikunto, S. (2013). Prosedur penelitian suatu pendekatan praktik. Jakarta: Rineka Cipta.
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Huizinga, T., M. E. Weinblatt, N. Shadick, C. Heegaard Brahe, M. Ǿstergaard, M. L. Hetland, S. Saevarsdottir et al. „AB1243 TRAINING AND VALIDATION OF A MULTIVARIATE PREDICTOR OF RISK OF RADIOGRAPHIC PROGRESSION FOR PATIENTS WITH RHEUMATOID ARTHRITIS“. Annals of the Rheumatic Diseases 79, Suppl 1 (Juni 2020): 1913.1–1913. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1872.
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Background:The multi-biomarker disease activity (MBDA) score, adjusted for age, sex and adiposity (MBDAadj), has been shown to be better than several conventional disease activity measures for predicting risk for radiographic progression (RP) in patients with rheumatoid arthritis (RA).1Serologic status and other non-disease activity measures are also predictive of RP risk. Combining them with the MBDAadjshould result in a stronger prognostic test for RP than any one measure alone.Objectives:Develop a multivariate model for predicting risk for RP that includes the adjusted MBDA score and other known predictors of RP.Methods:Four RA cohorts were used, two for training (OPERA and BRASS, n=555) and two for validation (SWEFOT and Leiden, n=397). Each pair of cohorts was heterogeneous in disease duration and treatment history. BMI data were not available for one validation cohort, so a BMI surrogate was modeled using forward selection with the two training cohorts and 3 others (CERTAIN, InFoRM, RACER) (N=1411). An RP risk score was then trained using forward selection in a linear mixed-effects regression, considering disease-related and demographic variables as predictors of change in modified total Sharp score over one year (ΔmTSS), with a random effect on cohort. The RP risk score was validated as a predictor of RP with two cutoffs (ΔmTSS >3 and >5) using logistic mixed-effects regression. Odds ratios (OR) and 95% profile likelihood-based confidence intervals (CI) were calculated from the models and significance was assessed by likelihood ratio tests. Risk curves were generated to show probability of RP as a function of the RP risk score.Results:The BMI surrogate included leptin, sex, age and age2and correlated well with BMI (ρ = 0.76). In training, the most significant independent predictors of RP were MBDAadj(p = 0.00020), seropositivity (p = 9.3 x 10-5), BMI surrogate score (p = 0.013) and use of targeted therapy (p = 0.0026). The final model was: RP risk score = 0.024 x MBDAadj+ 0.093 if seropositive – 0.063 x BMI surrogate score – 0.61 if using a targeted therapy. In validation, the OR (95% CI) of the RP risk score for predicting ΔTSS >3 or >5 were 2.2 (1.6, 3.2) (p = 2.6 × 10-6) and 3.1 (2.0, 5.0) (p = 5.7 × 10-8), respectively (Figure 1). The odds of a patient having RP increases by 50% for each 21-unit or 15-unit increase in MBDAadj, for RP defined as ΔTSS >3 or >5, respectively.Figure 1.Conclusion:A multivariate model containing adjusted MBDA score, seropositivity, a BMI surrogate and use of targeted therapy has been trained and validated as a prognostic test for radiographic progression in RA.References:[1]Curtis, et al.Rheumatology [Oxford].2018;58:874Disclosure of Interests:Thomas Huizinga Grant/research support from: Ablynx, Bristol-Myers Squibb, Roche, Sanofi, Consultant of: Ablynx, Bristol-Myers Squibb, Roche, Sanofi, Michael E. Weinblatt Grant/research support from: BMS, Amgen, Lilly, Crescendo and Sonofi-Regeneron, Consultant of: Horizon Therapeutics, Bristol-Myers Squibb, Amgen, Abbvie, Crescendo, Lilly, Pfizer, Roche, Gilead, Nancy Shadick Grant/research support from: Mallinckrodt, BMS, Lilly, Amgen, Crescendo Biosciences, and Sanofi-Regeneron, Consultant of: BMS, Cecilie Heegaard Brahe: None declared, Mikkel Ǿstergaard Grant/research support from: AbbVie, Bristol-Myers Squibb, Celgene, Merck, and Novartis, Consultant of: AbbVie, Bristol-Myers Squibb, Boehringer Ingelheim, Celgene, Eli Lilly, Hospira, Janssen, Merck, Novartis, Novo Nordisk, Orion, Pfizer, Regeneron, Roche, Sandoz, Sanofi, and UCB, Speakers bureau: AbbVie, Bristol-Myers Squibb, Boehringer Ingelheim, Celgene, Eli Lilly, Hospira, Janssen, Merck, Novartis, Novo Nordisk, Orion, Pfizer, Regeneron, Roche, Sandoz, Sanofi, and UCB, Merete L. Hetland Grant/research support from: BMS, MSD, AbbVie, Roche, Novartis, Biogen and Pfizer, Consultant of: Eli Lilly, Speakers bureau: Orion Pharma, Biogen, Pfizer, CellTrion, Merck and Samsung Bioepis, Saedis Saevarsdottir Employee of: Part-time at deCODE Genetics/Amgen Inc, working on genetic research unrelated to this project, Megan Horton Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Brent Mabey Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Darl Flake Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Rotem Ben-Shachar Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Eric Sasso Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Alexander Gutin Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Elena Hitraya Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Jerry Lanchbury Shareholder of: Myriad Genetics, Inc., Employee of: Myriad Genetics, Inc., Jeffrey Curtis Grant/research support from: AbbVie, Amgen, Bristol-Myers Squibb, Corrona, Janssen, Lilly, Myriad, Pfizer, Regeneron, Roche, UCB, Consultant of: AbbVie, Amgen, Bristol-Myers Squibb, Corrona, Janssen, Lilly, Myriad, Pfizer, Regeneron, Roche, UCB
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Attiogbé, Christian, Flavio Ferrarotti und Sofian Maabout. „Advances and Challenges for Model and Data Engineering“. JUCS - Journal of Universal Computer Science 27, Nr. 7 (28.07.2021): 646–49. http://dx.doi.org/10.3897/jucs.70972.
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Following the stimulating discussions in the workshops held during the 9th International Conference on Model and Data Engineering (MEDI 2019), we proposed to edit a special issue compiling the fruitful research resulting from those discussions. This special issue on current research in model and data engineering of the Journal of Universal Computer Science is the outcome of that proposal. As such, it contains thoroughly revised and significantly extended versions of key papers discussed at MEDI 2019 workshops. The main objective of MEDI is to provide a forum for the dissemination of research accomplishments and to promote the interaction and collaboration between the models and data research communities. MEDI provides an international platform for the pre- sentation of research on models and data theory, development of advanced technologies related to models and data and their advanced applications. This international scientific event, initiated by researchers from Euro-Mediterranean countries in 2011, aims also at promoting the creation of north-south scientific networks, projects and faculty/student exchanges. The following seven accepted papers nicely reflect the wide range of topics covered by MEDI conferences. In their paper “Enhancing GDPR Compliance Through Data Sensitivity and Data Hiding Tools”, Xabier Larrucea, Micha Moffie and Dan Mor consider the problem of fulfilling the rules set by the General Data Protection Regulation (GDPR) of the EU within the framework of the reference architectural model industry 4.0 for the healthcare sector. This is challenging due to the highly sensitive data managed by this sector and the need to share this data between different national healthcare providers within the EU. The authors propose and implement a series of valuable tools to enhance security and privacy in this context as well as compliance with the GDPR. They also illustrate through a case study the use of the proposed tools for sharing health records and their integration within the reference framework. In their paper “BSO-MV: An Optimized Multiview Clustering Approach for Items Recommendation in Social Networks”, Lamia Berkani, Lylia Betit and Louiza Belarif present a new approach to improve accuracy and coverage of clustering based recommendations systems for social networks. The approach is based on improving the results of multiview clustering by combining it with a bees swarm optimization algorithm. Through extensive experimentation with two real-world datasets, they are able to demonstrate the effectiveness of the proposed approach to significantly improve accuracy, outperforming others clustering-based approaches. In their paper “A Formal Model for Configurable Business Process with Optimal Cloud Resource Allocation”, Abderrahim Ait Wakrime, Souha Boubaker, Slim Kallel, Emna Guermazi and Walid Gaaloul propose a formal approach to analyse and verify con- figurable business process models as well as to optimize the cost of their implementation in the Cloud. The mechanism consists on transforming the problem into an equivalent Boolean satisfiability problem (SAT) which is then feed to a solver. This transformation is done by means of translation rules from configurable business processes to SAT. This model formalizes the different configurable process behaviors including control-flow and cloud resource allocations, enabling the derivation of correct configuration variants. Weighted partial SAT formulae are integrated in the model in order to optimize the global cloud resource allocation cost. In their paper “Towards a Semantic Graph-based Recommender System: A Case Study of Cultural Heritage”, Sara Qassimi and El Hassan Abdelwahed present a semantic graph-based recommender system of cultural heritage places. Their approach consists on first constructing an emergent description that semantically augments the information about the places of interest and then model through graphs the semantic relationships between similar cultural heritage places and their associated tags. Note that the unsuper- vised nature of folksonomy’s tags semantically weakens the description of resources, which in turn hinders their indexing and decreases the quality of their classification and clustering. The semantic augmentation produced by the proposed method in the case study of cultural heritage places in Marrakesh city shows to be an effective tool to fight information overload and to produce better recommendations in this context. As such, the paper presents a valuable contribution that can be used to improve the quality of recommender systems in general. In their paper “Assembling the Web of Things and Microservices for the Management of Cyber-Physical Systems”, Manel Mena, Javier Criado, Luis Iribarne and Antonio Corral face the challenge of facilitating communication between the diverse devices and protocols used by Cyber-Physical Systems (CPS) and the Internet of Things (IoT). They propose an approach based on the concept of digital dice (an abstraction of various objects). The digital dice builds on the web of things standard. It is based on microservices and capable of handling the interaction and virtualization of IoT devices. This work introduces a technique to build, transform and compose digital dices from descriptions of “things”. A full transformation flow is presented and a case study is used to illustrate its implementation. The proposal is shown to be effective and flexible, improving the state of the art. In their paper “Model-Driven Engineering for End-Users in the Loop in Smart Ambient Systems”, Sylvie Trouilhet, Jean-Paul Arcangeli, Jean-Michel Bruel and Maroun Koussaifi present a Model-Driven Engineering (MDE) approach to involve the user in the process of constructing at run time component based applications, adapted to a situation and user needs, in the context of ambient systems. The proposed solution relies on several domain-specific languages and a transformation process, based on established MDE tools (Gemoc Studio, Eclipse Modeling Framework, EcoreTools, Sirius and Acceleo). In this context, the authors describe an innovative way of reinforcing the place of the user in the engineering loop. The authors propose an editor that allows the end user to be aware of the emerging applications resulting of this process, to understand their function and use, and to modify them if desired. From these actions, feedback data are extracted to improve the process. In their paper “An Approach for Testing False Data Injection Attack on Data Depen- dent Industrial Devices”, Mathieu Briland and Fabrice Bouquet present a domain specific language (DSL) for generating test data for IoT devices/environments. The DSL is proposed for testing and simulating false data injection attacks (FDIA). First, the paper outlines a generic approach for FDIA and presents a list of possible sensor types and a categorization schema for data obtained from sensors. Then, the application of the DSL is illustrated using two examples; a simple one altering the data obtained from a temperature sensor and a more complex one concurrently altering the data obtained from three particle sensors. The authors show that their approach works well in the case study of the Flowbird parking meter system and discuss how it can be adapted to different application domains. We are grateful to all authors of journal articles in this issue, who contributed to a fine collection of research in model and data engineering. We would like to express our greatest thanks to all reviewers, who put in a lot of time reading the articles and making substantial suggestions for improvement, which at the end led to the high quality. We also would like to thank J.UCS evaluation committee for the opportunity to publish this collection of research articles as a special issue of the Journal of Universal Computer Science and in particular to the publishing managers Dana Kaiser and Johanna Zeisberg for their timeless assistance during the whole process. Last but not least, we would like to acknowledge to our host institutions, the University of Nantes and the Software Competence Center Hagenberg (SCCH) for their support and sponsoring of this special issue. In particular, Prof. Yamine Ait-Ameur and its host institute IRIT/INP-ENSEEIHT have significantly collaborated with this special issue in the framework of the COMET scientific partnership agreement with SCCH, and have also supported the MEDI confer- ence from which it originated. Christian Attiogbé, Flavio Ferrarotti and Sofian Maabout (July, 2021)
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Ratnaningsih, Tri, und Ana Septia Rahman. „PENGARUH KOMPETENSI TERHADAP KINERJA PEGAWAI PADA BIRO PEMBINAAN OPERASI MABES POLRI JAKARTA“. Jurnal Arastirma 1, Nr. 1 (28.02.2021). http://dx.doi.org/10.32493/arastirma.v1i1.10071.
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Tujuan. Tujuan penelitian ini adalah untuk mengetahui seberapa besar pengaruh kompetensi terhadap kinerja pegawai pada Biro Pengembangan Operasi Mabes Polri.Metode. Metode penelitian ini menggunakan metode deskriptif kuantitatif dengan populasi dalam penelitian ini sebanyak 48 pegawai pada Biro Pengembangan Operasi Mabes Polri. Metode penelitian sampel adalah sampel jenuh dimana semua populasi dijadikan sampel, metode analisis dalam pengolahan data penelitian ini menggunakan metode analisis deskriptif, uji korelasi product moment pearson, koefisien determinasi dan uji hipotesis (test).Hasil. Hasil penelitian ini menunjukkan bahwa terdapat pengaruh yang signifikan antara Kompetensi terhadap Kinerja Karyawan dengan nilai regresi Y = 17,85 + 0,685X yang artinya apabila setiap penambahan 1 (satu) poin variabel kompetensi maka akan meningkatkan kinerja sebesar 0,607 kali dengan kecepatan konstan. sebesar 17,85. Nilai koefisien korelasi sebesar 0,7402 artinya variabel kompetensi mempunyai tingkat hubungan yang kuat dengan variabel kinerja. Dari perhitungan Koefisien Determinasi (KD) diperoleh sebesar 0,5479, dapat disimpulkan bahwa kompetensi memberikan kontribusi terhadap kinerja pegawai sebesar 54,79% sedangkan sisanya sebesar 45,21% dipengaruhi oleh faktor lain yang tidak diteliti. Pengujian hipotesis dengan menggunakan uji statistik diperoleh > atau 7,461> 2,013 yang artinya Ha diterima dan Ho ditolak, artinya terdapat hubungan yang signifikan antara kompetensi dengan kinerja pegawai pada Biro Pengembangan Operasi Mabes Polri Jakarta.Implikasi. Biro Operasional Mabes Polri harus rutin melakukan pelatihan kepada seluruh pegawai sesuai dengan standar manajemen agar pegawai dapat menyelesaikan tugas dengan cepat dan tepat, serta selalu konsisten dalam memberikan waktu kepada pegawai untuk menyelesaikan tugas guna mencapai target hasil kerja yang telah ditetapkan. efektif dan efisien.
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Saputri, Fiqih Hana, Syaipul Ramdhan und Nurul Ainun Baktiar. „Perancangan Game Edukasi Marbel Mengenal Huruf Hijaiyah Menggunakan Metode t-Test“. JURNAL SISFOTEK GLOBAL 11, Nr. 1 (30.03.2021). http://dx.doi.org/10.38101/sisfotek.v11i1.343.
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Perkembangan teknologi yang pesat ini berpengaruh terhadap proses pembelajaran di Taman Kanak-Kanak dan berpengaruh juga pada materi pembelajaran serta cara penyampaian materi dalam proses kegiatan belajar mengajar. Mempelajari dasar Alquran salah satunya dimulai dengan mempelajari huruf hijaiyah. Guru biasanya menyampaikan materi hanya ceramah atau bercakap-cakap, sehingga siswa sering merasa jenuh. Dalam menghafal huruf hijaiyah perlu metode yang menarik seperti game edukasi yang bisa diakses dengan mudah melalui smartphone. Metode yang digunakan dalam penelitian ini yaitu metode kualitatif dan metode selanjutnya menggunakan OOAD yang di gambarkan dengan UML. Hasil penelitian ini yaitu, game edukasi MARBEL (Mari Belajar) dan mengenal huruf hijaiyah yang dibuat menggunakan Construct 2 ini terdapat ada perbedaan secara signifikan dan efektif digunakan untuk anak TK.
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Alsuhabi, Hassan, und Rhonda Magel. „Nonparametric Tests for the Umbrella Alternative with Unknown Peak in a Mixed Design“. Asian Journal of Probability and Statistics, 13.06.2020, 1–13. http://dx.doi.org/10.9734/ajpas/2020/v7i330182.
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Aims: Introducing and comparing 4 different tests for the unknown umbrella alternative in a mixed design.
Study Design: Simulation study consisting of a randomized complete block portion and a completely randomized design portion for various underlying distributions.
Place and Duration of Study: Simulation Study – conducted at North Dakota State University from September 2018 through December 2019.
Methodology: This paper proposes four non-parametric tests for testing the umbrella alternative with unknown peak when the data are mixture of a randomized complete block and a completely randomized design. The proposed tests are various combinations of a modified (unmodified) Mack-Wolfe’s test and a modified (unmodified) Kim-Kim’s test, respectively. In this paper, the proposed tests are an extension of Magel et al. (2010) and Hassan and Magel (2020) peak known tests to the unknown peak setting. The four proposed test statistics are compared to each other.
Results: When there were 3 populations, the unmodified versions of the test statistics did better than the modified versions. When there were 4 and 5 populations, the results varied.
Conclusion: All of the test statistics reached their asymptotic distributions quickly. The standardize first versions of the test statistics were generally better than the standardized last version of the test statistics, which meant that it was better to place equal weights on the RCBD portion and the CRD portion.
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Mushaffa, Waode, Muhaimin Hamzah und Indriyani Nur. „Pertumbuhan Cangkang Kerang Mutiara Pteria penguin yang Diimplantasi yang Dibudidayakan dengan Metode Gantung di Perairan Palabusa Selat Buton“. JSIPi (Jurnal Sains dan Inovasi Perikanan) (Journal of Fishery Science and Innovation) 2, Nr. 2 (18.07.2018). http://dx.doi.org/10.33772/jsipi.v2i2.7574.
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The producing half-pearls (Mabe) at the Palabusa waters of Buton Strait Southeast Sulawesi still uses simple technology, namely applying implantation with only a single nuclei, which has an impact on the large number of seeds and used space. Therefore, in order to increase the production of mabe pearls, one of effort is by planting two nucleus in a single mabe pearl shell. The test animals used were P. penguin as many as 90 oysters, with an average length of 12 cm shells, 8 cm shell height and 100-120 g individual weights. The nucleus used was made from plastic (half round) with diameter of 10 cm and height of 0.8 cm. This research was conducted for four months. The study was designed using a completely randomized design with 3 treatments and 3 replications. The treatment applied was A (a nucleus was inserted into the left shell), B (2 nuclei were inserted into the left shell), and C (a nucleus was inserted into each on the left and right shells). The results showed that all treatments did not have a significant effect on the growth of shells. Hence, the addition of two nuclei in a single pearl oyster can be used to increase cultivation production. Keywords : Pteria penguin, implantation, nucleus, growth
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Dominiak, Adam, und Jean-Philippe Lefort. „Ambiguity and Probabilistic Information“. Management Science, 05.11.2020. http://dx.doi.org/10.1287/mnsc.2020.3705.
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Experiments detecting ambiguity aversion often rely on the assumption that probabilities are exogenously given for some uncertain events. However, the canonical models that accommodate ambiguity into economic theory, such as the maxmin expected utility (MEU) and Choquet expected utility (CEU) models, are purely subjective. These models do not specify how subjects could incorporate exogenous probabilities into decisions. We study two approaches for embedding exogenous probabilities in the context of the thought experiments suggested by Mark Machina. We show that Machina’s choice behavior entails fundamentally different consequences for the ambiguity models mentioned; although it violates the CEU model, it is consistent with the MEU model. For the latter model, Machina’s experiments can test whether individuals adhere to expected utility for prospects whose consequences occur with the exogenously given probabilities. This paper was accepted by Manel Baucells, decision analysis.
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Anif, Sofyan. „Profil Kompetensi Profesional Guru Mapel Biologi Pasca Sertifikasi di Karesidenan Surakarta“. Jurnal VARIDIKA 25, Nr. 2 (14.07.2015). http://dx.doi.org/10.23917/varidika.v25i2.720.
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As stated in UU No. 14, 2005 and PP No. 74, 2008 that teachers as proffessional educator have to possess four competences, namely: pedagogic, proffessional, character, and social. However the condition in Indonesia is not like that. In general, they are in low category, specifically in pedagogic and proffessional. Those conditions happen in biology teachers and other teacher subjects. Then the aim of this study is to observe the profile of biology teachers especially their proffessional competence pasca sertification in Surakarta residance. The population of this study is all biology teachers (332 persons) that have rechieved sertification through direct, portofolio, and PLPG program. Purposive random sampling is used to get 116 teachers. Data are collected by depth interview, documentation, and test, then the collected data are analysed by descriptive qualitative. The result shows that the profile of proffessional competence of biology teachers can be grouped into three: low, middle, and high. The teachers are low in: concept implementation, using tool of measurements, biology experiment planning, using the result of reflection, self reflection, understanding the principles and theories of savety work, doing action research, and understanding the steps of biology experiement correctly. The teachers are middle in: understanding the objective of the study, creative and innovative in implementing and developing science of biology nad correlated sciences, undesrtanding thinking process of biology, using symbolic language, undesrtanding standard competence, and understanding the scoupe of biology. They are high in: understanding the structure biology science and its correlation, selecting the material, cooking the material creatively, understanding the concepts, laws, and biology theories, undesrtanding the history of the natural science, specifically biology, understanding the basic competence of the subject or topic, updating their knowledge from many sources, and rationally qualitatively and quantitatively in understanding the process and biology law.
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Sonsino, Doron, Yaron Lahav und Yefim Roth. „Reaching for Returns in Retail Structured Investment“. Management Science, 20.04.2021. http://dx.doi.org/10.1287/mnsc.2020.3932.
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The growing market for retail structured investment products and empirical evidence for excessive pricing of such products raise the hypothesis that private investors show increased risk appetite in structured investment contexts. A two-stage framed field experiment building on cumulative prospect theory is designed to test this hypothesis. Subjects’ expectations regarding the future performance of an underlying index are elicited first. A bisection algorithm is then applied to derive the certainty equivalents of 20 simple individually tailored deposits. The results support the increased risk appetite hypothesis, revealing that subjects reach for substantial gains and underweight tail loss events when evaluating the deposits. Similar results emerge in a follow-up experiment where the uncertain deposits are replaced by risky versions. While previous studies propose that misperception of complex terms and optimism contribute to the mispricing of structured instruments, the current experiments show that nonstandard risk appetite manifests in the valuation of simple well-defined products, controlling for expectations. This paper was accepted by Manel Baucells, decision analysis.