Auswahl der wissenschaftlichen Literatur zum Thema „T cell diversity“
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Zeitschriftenartikel zum Thema "T cell diversity"
Newrzela, S., N. Al-Ghaili, T. Heinrich, M. Petkova, S. Hartmann, B. Rengstl, A. Kumar et al. „T-cell receptor diversity prevents T-cell lymphoma development“. Leukemia 26, Nr. 12 (30.05.2012): 2499–507. http://dx.doi.org/10.1038/leu.2012.142.
Der volle Inhalt der QuelleStromberg, Sean P., und Jean M. Carlson. „Diversity of T-cell responses“. Physical Biology 10, Nr. 2 (15.03.2013): 025002. http://dx.doi.org/10.1088/1478-3975/10/2/025002.
Der volle Inhalt der QuelleGORONZY, J., W. LEE und C. WEYAND. „Aging and T-cell diversity☆“. Experimental Gerontology 42, Nr. 5 (Mai 2007): 400–406. http://dx.doi.org/10.1016/j.exger.2006.11.016.
Der volle Inhalt der QuelleNelson, J. „STKE: Celebrating T Cell Diversity“. Science 295, Nr. 5557 (08.02.2002): 933b—933. http://dx.doi.org/10.1126/science.295.5557.933b.
Der volle Inhalt der QuelleRobins, Harlan S., Paulo V. Campregher, Santosh K. Srivastava, Abigail Wacher, Cameron J. Turtle, Orsalem Kahsai, Stanley R. Riddell, Edus H. Warren und Christopher S. Carlson. „Comprehensive assessment of T-cell receptor β-chain diversity in αβ T cells“. Blood 114, Nr. 19 (05.11.2009): 4099–107. http://dx.doi.org/10.1182/blood-2009-04-217604.
Der volle Inhalt der QuelleSato, Kayoko. „Helper T Cell Diversity and Plasticity“. Circulation Journal 78, Nr. 12 (2014): 2843–44. http://dx.doi.org/10.1253/circj.cj-14-1164.
Der volle Inhalt der QuelleBorn, Willi K., M. Kemal Aydintug und Rebecca L. O'Brien. „Diversity of γδ T-cell antigens“. Cellular & Molecular Immunology 10, Nr. 1 (22.10.2012): 13–20. http://dx.doi.org/10.1038/cmi.2012.45.
Der volle Inhalt der QuelleParish, Ian A., und Susan M. Kaech. „Diversity in CD8+ T cell differentiation“. Current Opinion in Immunology 21, Nr. 3 (Juni 2009): 291–97. http://dx.doi.org/10.1016/j.coi.2009.05.008.
Der volle Inhalt der QuelleNakayamada, Shingo, Hayato Takahashi, Yuka Kanno und John J. O'Shea. „Helper T cell diversity and plasticity“. Current Opinion in Immunology 24, Nr. 3 (Juni 2012): 297–302. http://dx.doi.org/10.1016/j.coi.2012.01.014.
Der volle Inhalt der QuelleKemir, C. „Diversity of Human T Cell Receptors“. Science 288, Nr. 5469 (19.05.2000): 1135a—1135. http://dx.doi.org/10.1126/science.288.5469.1135a.
Der volle Inhalt der QuelleDissertationen zum Thema "T cell diversity"
Golby, Sarah Jane Charity. „Diversity of T cell subsets in mucosal microenvironments“. Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369221.
Der volle Inhalt der QuelleFurmanski, Anna Louise. „Diversity and selection of the murine T-cell repertoire“. Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434779.
Der volle Inhalt der QuelleLee, Edward S. „Quantifying the development, size, and repertoire diversity of T cell populations“. Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/31002/.
Der volle Inhalt der QuelleTrichot, Coline. „Regulation of Human T Helper Cell Diversity : From In Vitro Dendritic Cell-Based Mechanisms to Candidate Biomarkers in Atopic Dermatitis“. Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS423.
Der volle Inhalt der QuelleHuman immunity is essentially driven by dendritic cells and T helper cells. When dendritic cells detect a pathogen, they will instruct T helper cells to adopt the adapted phenotype for the specific threat encountered. T helper cells are subdivided in multiple subsets, characterized by particular sets of cytokines. Each T helper subset has specific functions and is involved in the clearance of distinct pathogens. If T helper responses are not precisely regulated, they can become pathogenic, in this case T helper pathways can be considered as potential targets for therapy. In this context, I focused my PhD work on studying T helper cell subset diversity and regulation. First, I demonstrated the ability of TSLP-activated dendritic cell to induce T follicular helper cell polarization. Then I participated in building a mathematical model capable of predicting T helper cell response to dendritic-cell derived signals. This model allowed us to identify the specific role of IL-12p70, in an IL-1 context, to induce IL-17F without IL-17A. Finally, I monitered eight T helper and T follicular helper cell populations in peripheral blood from atopic dermatitis patients treated with Dupilumab, an immunotherapy targeting the IL-4 receptor alpha subunit, and was able to show a correlation between decrease of Th17 cell percentage and improvement of EASI clinical score. Overall, my work on Th phenotype diversity provides key mechanistic insight with potential application in immunotherapy
Stirk, Emily Ruth. „Stochastic modelling of diversity and ageing in the naive T cell repertoire“. Thesis, University of Leeds, 2010. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531516.
Der volle Inhalt der QuelleBrookes, Roger Hamilton. „Generation of diversity in T cell epitope hierarchy by different routes of immunisation with simian immunodeficiency virus core protein“. Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283133.
Der volle Inhalt der QuelleSingh, Ogesh. „Regulatory T cell diversity analysis and a gene transfer approach to cellular immunotherapy in a murine model of type one diabetes“. Thesis, Royal Veterinary College (University of London), 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522749.
Der volle Inhalt der QuelleJurewicz, Mollie M. „The non-classical MHC-II molecule DO regulates diversity of the immunopeptidome and selection of the CD4 regulatory T cell lineage“. eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1030.
Der volle Inhalt der QuelleAmeres, Stefanie Verfasser], und Horst [Akademischer Betreuer] [Domdey. „The T cell repertoire specific for the IE-1 protein of human cytomegalovirus : diversity, function and evasion / Stefanie Ameres. Betreuer: Horst Domdey“. München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2013. http://d-nb.info/104831099X/34.
Der volle Inhalt der QuelleKarpf, Léa. „Systematic Study of OX40 Ligand Context-Dependent Function on Human T Helper Cell Polarization A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication TH Cell Diversity and Response to Dupilumab in Patients With Atopic Dermatitis Inborn Errors of Type I IFN Immunity in Patients With Life-Threatening COVID-19 Quantitative Modeling of OX40 Ligand Context-Dependent Function on Human T Helper Cell SARS-CoV-2 Induces Activation and Diversification of Human Plasmacytoid Pre-Dendritic Cells“. Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASL044.
Der volle Inhalt der QuelleAdaptive immunity is mainly orchestrated by CD4 T helper cells. They have the ability to polarize in several subsets, each associated to a suitable phenotype for the encounter pathogen. T helper cell activation can be regulated by co-stimulator, such as OX40 Ligand, or co-inhibitor immune checkpoint molecules. These molecules have been studied individually, in specific conditions. However, context-dependency may explain large parts of the functional variability of biological molecules on a given output. Currently, there is no framework to analyze and quantify context-dependency of a molecule over multiple contexts and response outputs. My PhD project focused on OX40L function on T helper cell polarization, in 4 molecular and 11 cellular contexts. We measured 17 T helper cytokines and developed a statistical modeling strategy to quantify OX40L context-dependency on these cytokines. This revealed highly variable qualitative and quantitative context-dependency scores, depending on the output cytokine and context type. Among molecular contexts, Th2 was the most influential on OX40L function. Among cellular contexts, dendritic cell type rather than activating stimulus was dominant in controlling OX40L contextdependency. My thesis work unveils the complex determinants of OX40L function, provides a unique framework to quantify the context-dependent functional variability of any biomolecule, and supports that context-dependency should be more taken into consideration in future studies
Bücher zum Thema "T cell diversity"
B, Schook Lawrence, Tew John G und International RES Symposium (1987 : Richmond, Va.), Hrsg. Antigen presenting cells: Diversity, differentiation, and regulation : proceedings of a symposium held in Richmond, Virginia, March 26-29, 1987. New York: Liss, 1988.
Den vollen Inhalt der Quelle findenGalley, Kevin Andrew. Analysis of junctional region diversity of TCR[beta] cDNA from pancreatic islet-infiltrating T cells of young prediabetic nonobese diabetic mice. Ottawa: National Library of Canada, 1994.
Den vollen Inhalt der Quelle findenSoboloff, Jonathan, und Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.
Den vollen Inhalt der Quelle findenSoboloff, Jonathan, und Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.
Den vollen Inhalt der Quelle findenSoboloff, Jonathan, und Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2021.
Den vollen Inhalt der Quelle findenSoboloff, Jonathan, und Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.
Den vollen Inhalt der Quelle findenSoboloff, Jonathan, und Dietmar J. Kappes. Signaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.
Den vollen Inhalt der Quelle findenSignaling Mechanisms Regulating T Cell Diversity and Function. Taylor & Francis Group, 2017.
Den vollen Inhalt der Quelle findenKlingenberg, Roland, und Ulf Müller-Ladner. Mechanisms of inflammation. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0270.
Der volle Inhalt der QuelleLiede-Schumann, Sigrid, Ulrich Meve, Gildas Gâteblé, Gabrielle Barriera und Silvio Fici. Apocynaceae pro parte, Phellinaceae, Capparaceae : Flore de la Nouvelle Calédonie, volume 27. Publications scientifiques du Muséum, Paris ; IRD, Marseille, 2020. http://dx.doi.org/10.5852/fft49.
Der volle Inhalt der QuelleBuchteile zum Thema "T cell diversity"
Gustafson, Claire E., David L. Lamar, Cornelia M. Weyand und Jörg J. Goronzy. „Age, T Cell Homeostasis, and T Cell Diversity in Humans“. In Handbook of Immunosenescence, 303–22. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-99375-1_9.
Der volle Inhalt der QuelleGustafson, Claire E., David L. Lamar, Cornelia M. Weyand und Jörg J. Goronzy. „Age, T Cell Homeostasis, and T Cell Diversity in Humans“. In Handbook of Immunosenescence, 1–20. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-64597-1_9-1.
Der volle Inhalt der QuellePurushe, Janaki, und Yi Zhang. „Histone Methyltransferases and T Cell Heterogeneity“. In Signaling Mechanisms Regulating T Cell Diversity and Function, 203–29. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-11.
Der volle Inhalt der QuelleO’Boyle, Kaitlin C., Takuya Ohtani, Sasikanth Manne, Bertram Bengsch, Sarah E. Henrickson, E. John Wherry und Cecile Alanio. „Exploration of T-Cell Diversity Using Mass Cytometry“. In Methods in Molecular Biology, 1–20. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0266-9_1.
Der volle Inhalt der QuelleCho, Jonathan J., Kyle J. Lorentsen und Dorina Avram. „Models of Regulatory T Cell Alterations and Systemic Autoimmunity“. In Signaling Mechanisms Regulating T Cell Diversity and Function, 231–48. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-12.
Der volle Inhalt der QuelleCharbonnier, Louis-Marie, und Talal A. Chatila. „Phenotypic and Functional Characterization of Regulatory T Cell Populations“. In Signaling Mechanisms Regulating T Cell Diversity and Function, 105–18. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-7.
Der volle Inhalt der QuelleFahl, Shawn P., Dietmar J. Kappes und David L. Wiest. „TCR Signaling Circuits in αβ/γδ T Lineage Choice“. In Signaling Mechanisms Regulating T Cell Diversity and Function, 85–104. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-6.
Der volle Inhalt der QuelleHeller, Nicola M., Rosa Berga-Bolanos, Lynette Naler und Jyoti Misra Sen. „Natural Killer T (NKT) Cells in Mice and Men“. In Signaling Mechanisms Regulating T Cell Diversity and Function, 119–46. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-8.
Der volle Inhalt der QuelleBarnett, John B. „Consequences of Blocking the Choreography of Double Negative Thymocyte Maturation“. In Signaling Mechanisms Regulating T Cell Diversity and Function, 1–16. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-1.
Der volle Inhalt der QuelleSamakai, Elsie, Christina Go und Jonathan Soboloff. „Defining the Roles of Ca2+ Signals during T Cell Activation“. In Signaling Mechanisms Regulating T Cell Diversity and Function, 177–202. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371689-10.
Der volle Inhalt der QuelleKonferenzberichte zum Thema "T cell diversity"
Grinshpun, Boris, Jennifer Sims, Peter Canoll, Jeffrey N. Bruce, Peter Sims und Yufeng Shen. „Analyzing T cell repertoire diversity by high-throughput sequencing“. In 2013 IEEE Global Conference on Signal and Information Processing (GlobalSIP). IEEE, 2013. http://dx.doi.org/10.1109/globalsip.2013.6736810.
Der volle Inhalt der QuelleBaracho, Gisele V., Stephanie Widmann und Aaron Tyznik. „Abstract 1815: Defining cell population diversity and T cell dysfunction in a mouse model of obesity“. In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1815.
Der volle Inhalt der QuellePatel, Preeyam, Marcos Iglesias, Qin Tang, Megan Biller, Alireza Alavi und Ayako Pedersen. „1029 T cell receptor diversity analysis ofin vitro-expanded T cells against IDO1 and PD-L1-derived peptides“. In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.1029.
Der volle Inhalt der QuelleYuguo, Song, Xiang Lei und Bi Shengli. „Analysis of T cell receptor V beta diversity in peripheral CD8(+) T lymphocytes in patients with hepatitis B infection“. In 2011 International Conference on Human Health and Biomedical Engineering (HHBE). IEEE, 2011. http://dx.doi.org/10.1109/hhbe.2011.6027968.
Der volle Inhalt der QuelleISHIDA, Y. „A STABILITY AND DIVERSITY ANALYSIS ON A MATHEMATICAL MODEL OF THE INTERACTION BETWEEN HIV AND T-CELL CD4+“. In Proceedings of the Fourth Asian Symposium (ASCM 2000). WORLD SCIENTIFIC, 2000. http://dx.doi.org/10.1142/9789812791962_0036.
Der volle Inhalt der QuelleFan, Li, Angelo Harris, Patrick Franken, Matthew Loya, Gabrielle Suppa, Nora Pencheva, Susan Sun et al. „80 Association ofin situT-cell receptor diversity and tumor adjacent immune cells to checkpoint inhibitor response in head and neck squamous cell carcinoma (HNSCC)“. In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.0080.
Der volle Inhalt der QuelleChoudhury, Noura, Kai Lee Yap, Kazuma Kiyotani, Poh Yin Yew, Alexa Campanile, Tatjana Antic, Gary Steinberg, Jae-Hyun Park, Peter H. O'Donnell und Yusuke Nakamura. „Abstract 4899: Tumor T-cell receptor (TCR) diversity elucidates the immune response to genetic alterations of muscle-invasive bladder cancer“. In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4899.
Der volle Inhalt der QuelleGu, Chenyi, Kenichi Shimada, Lukas Kania, Daniel E. Michaud, Madeline G. Townsend und Jennifer L. Guerriero. „499 Myeloid diversity in hormone receptor positive breast cancer reveals myeloid and lymphoid signaling pathways that correlate with T cell inhibition“. In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.0499.
Der volle Inhalt der QuelleShu, Tong, Hong Zheng, Yunong Gao, Min Gao, Zhipeng Zhou und Jing Bai. „EP285/#110 Circulating T-cell receptor diversity as prognostic biomarker for PARP inhibitors maintenance therapy in high-grade serous ovarian cancer“. In IGCS 2022 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-igcs.376.
Der volle Inhalt der QuelleMackay, Sean, Jon Chen, Jeremy Patino, Y. David Seo, Seth Pollack und Jing Zhou. „Abstract LB-190: Single-cell polyfunctionality of circulating CD4+ T cells correlates with T cell receptor repertoire diversity of PBMCs, indicating potential synergistic activity and peripheral biomarker predictive of efficacy of intratumor injection of the toll-like receptor 4 agonist G100“. In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-lb-190.
Der volle Inhalt der QuelleBerichte der Organisationen zum Thema "T cell diversity"
Fahima, Tzion, und Jorge Dubcovsky. Map-based cloning of the novel stripe rust resistance gene YrG303 and its use to engineer 1B chromosome with multiple beneficial traits. United States Department of Agriculture, Januar 2013. http://dx.doi.org/10.32747/2013.7598147.bard.
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