Dissertationen: „Substance abuse Therapy“

1

Bosch, Louisa Maria Clementina van den. „Borderline personality disorder, substance abuse, and dialectical behavior therapy“. [Lisse : Amsterdam : Swets & Zeitlinger] ; Universiteit van Amsterdam [Host], 2003. http://dare.uva.nl/document/67403.

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2

Von, Tersch Elise. „Modified Eye Movement Desensitization Therapy Protocol Treating Substance Abuse Disorders“. ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7346.

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Quality substance abuse treatment is needed to help fight the battle against drug addiction. This qualitative study was designed to explore some of the approaches to eye movement desensitization (EMDR) therapy that therapists trained in Parnell's adapted EMDR model use in conjunction with treatment for addictions. The purpose of this narrative inquiry was to investigate the experience of therapists who incorporate substance abuse treatment with Parnell's adapted EMDR model when treating trauma and substance use disorders. The population studied comprised licensed mental health therapists who had completed Parnell's EMDR training and implemented Parnell's modified EMDR protocol in their professional practice. The data from 9 participant interviews were coded and NVIVO data analysis software was used to identify key concepts and themes including deviations from Parnell's modified protocol, incorporating addiction treatment within the modified protocol, and the importance of the resourcing phase in the modified protocol. The study findings provided a deeper understanding of the types of addiction therapies that therapists are using in conjunction with Parnell's EMDR model. The results also showed that that participants perceived Parnell's EMDR model, combined with addiction therapeutic techniques and approaches, as beneficial in treating those with trauma and substance use disorders. By integrating addiction therapies with Parnell's EMDR protocol, EMDR certified trainers may better educate EMDR trainees about useful strategies for treating dual diagnosed clients. The strategies may shorten the client's time in treatment and provide a strong foundation for therapists as they conduct therapy for dual diagnosed people.

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Vano, Anne Margaret. „Linguistic predictors of treatment success among female substance abusers“. Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3036603.

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4

O'Connor, Patrick H. „The family therapy of substance abuse implications for the Caribbean church /“. Theological Research Exchange Network (TREN), 1991. http://www.tren.com.

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5

Bubb, Tanielle Carmen. „Psychofortology of adults recovering from substance-use disorders“. Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/d1008117.

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Evaluating the psychofortology of adults recovering from a substance-use disorder has been identified as a research priority in South Africa. This is in line with calls from researchers in diverse fields of psychology for more attention to the resilience, strengths, resources and capacities of people. This study therefore aimed to explore and describe the coping resources, sense of coherence, happiness and satisfaction with life of adults recovering from a substance-use disorder within the Nelson Mandela Metropole. The sample consisted of 99 voluntary participants from various managed recovery centres within the Nelson Mandela Metropole. Participants were given a package of questionnaires to complete under the supervision of the researcher. The assessment consisted of a biographical questionnaire and four standardized paper and pencil measures namely; the Coping Resources Inventory (CRI), the Sense of Coherence Scale (SOC-29), the Affectometer 2 (AFM-2) and the Satisfaction with Life Scale (SWLS). A quantitative, non-experimental exploratory-descriptive research method was used. Data was analysed using descriptive statistics and the Pearson product-moment correlation coefficient. Key findings include the following: Results on the CRI revealed low average mean scores on both the Coping Resources Inventory and within all the five subscales. Results of the SOC-29 revealed a high average mean score for sense of coherence. Results of the AFM-2 revealed that more positive affect than negative affect is present, resulting in happiness. Results of the SWLS revealed an average level of satisfaction with life, with most participants’ reporting neutral levels of satisfaction with life. There were significant positive correlations between the coping resources, sense of coherence, happiness and satisfaction with life of the sample. This implies that these constructs can be categorized under the subdiscipline of psychofortology. Overall, these findings emphasized the need for more research into adults recovering from a substance-use disorder.

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6

Tran, Mailynn. „Art Exploration of Countertransference and Empathy Towards Clients with Substance Abuse“. Digital Commons at Loyola Marymount University and Loyola Law School, 2019. https://digitalcommons.lmu.edu/etd/770.

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This research incorporates a heuristic method of inquiry to reflect on the researcher’s response to clients with substance abuse. The research investigates if countertransference with this population comes off as empathy (taking in the perspective of the clients) or pity (feeling sorry for clients). Data was collected over a structured 6-week period through the researcher’s self-reflective process of creating art in responses to client artwork made during her practicum experience. Research is solely based on the researcher’s personal response to a select few clients and the resulting artwork and reflective writing. Four themes were initially extrapolated from immediate reflections, which were combined to form a more central understanding of the researcher’s countertransference. Through this process of investigation, the researcher addresses and challenged personal biases, stereotypes, and assumptions about this population to better understand the meaning of her countertransference.

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7

Bennett, Robert C. „Lived Experiences of Women Receiving Substance Abuse Treatment from Male Counselors“. Thesis, Walden University, 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=13808972.

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The cost of the misuse of drugs is significant. The impact is felt across multiple systems across America and is covered mostly by federal, state, and local governments. Women comprise a significant portion of the persons using illicit drugs. Treatment is an effective way of reducing substance misuse. However, research into the efficacy of treatment for women lag that of men. The Substance Abuse and Mental Health Services Administration reported that women receiving substance abuse treatment from a man had shorter stays in treatment and poorer outcomes than those who had a female counselor while in treatment. Phenomenological and relational-cultural theory (RCT) was used both as the design and conceptual lens to examine the experiences of 6 women, 18 and older, who had completed substance abuse treatment with a male as a primary counselor. Collection of data occurred through semistructured, in-depth, face-to-face interviews. Thematic analysis yielded five main ideas: (1) rapport-building skills, (2) genuineness, (3) empathy; (4) flexibility; and (5) acceptance. In addition to this, the women were questioned to whether they were offered a choice of a man or woman for a counselor. The result is that participants indicated that having a man as a counselor gave them an opportunity to interact with a positive role model, however, they suggested that women be offered a choice in the gender of counselor and accommodated whenever possible. The findings of this study will be made available to stakeholders of substance abuse treatment programs and in public health journals to serve as a basis for further research. The implication for social change is that the information contributes to sustaining women in treatment and improving treatment outcomes.

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8

Schmorr, Gloria R. „The therapeutic uses of music with inpatient chemically dependent males“. Click here for text online. The Institute of Clinical Social Work Dissertations website, 1998. http://www.icsw.edu/_dissertations/schmorr_1998.pdf.

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Dissertation (Ph.D.) -- The Institute for Clinical Social Work, 1998.
A dissertation submitted to the faculty of the Institute of Clinical Social Work in partial fulfillment for the degree of Doctor of Philosophy.

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9

Nhunzvi, Clement. „An occupatiobnal perspectice on the journey of recovery from substance abuse among young Zimbabwean men“. Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/13347.

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Includes bibliographical references.
Substance abuse is a rising global health and social problem that is associated with serious medical, psychiatric, family, occupational, legal, financial and spiritual problems. While recovery from substance abuse is possible, it is a subjective and contested process. To date, the recovery process has not been explored from an occupational perspective in Zimbabwe, where as many as 60% of all readmissions at Zimbabwe’s psychiatric referral centre during the period from January 2010 to December 2011 were secondary to substance-induced disorders, and less than three percent of these patients moved into long-term recovery or sustained sobriety with rehabilitation follow-up. This qualitative narrative inquiry explores the journey of recovery from substance abuse among young adult Zimbabwean men. The aim of the study was to investigate how occupations played a role in the recovery journeys of each of these men. Three young adult men identified as former substance abusers were purposively selected for the study. Data generation occurred through in-depth narrative interviews with each participant. Principles of trustworthiness and validation emphasising the persuasiveness, coherence and pragmatic use of the narratives were applied throughout the research process, and ethical issues in narrative research were upheld. Ethical clearance was applied for and granted by the University of Cape Town’s Human Ethics Research Committee and permission to do the research was sought and given by the Medical Research Council of Zimbabwe. The findings of the study — explanatory stories — were produced through narrative analysis. These stories revealed substance abuse to be an occupation associated with both positive and negative consequences. Recovery from such abuse emerged as an ongoing occupational transition negotiated through participation in other occupations, and influenced by both personal and environmental factors. The way in which occupations were abandoned, modified and newly adopted during the process of this occupational transition is discussed. The construction and reconstruction of a positive occupational identity was seen as central to the process of occupational transition. The study concluded that engagement and participation in ‘engaging occupations’ was an intricate contributor to the recovery journey for young adult Zimbabwean men, and that narrative interviews should be used in generating data to explore the occupational nature of life and its events.

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Liskin, Sung. „An Exploration of Existential Group Art Therapy for Substance Abuse Clients with a History of Trauma“. Digital Commons at Loyola Marymount University and Loyola Law School, 2016. https://digitalcommons.lmu.edu/etd/295.

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The purpose of this study was to explore existential group art therapy (EGAT) as an alternate or integrated method in treating clients with substance abuse and a history of trauma. Subjects for this study were male and/or female adults, ages 18 and older, volunteer participants who were in treatment for substance addiction at Tarzana Treatment Centers. A group of seven participants who met the criteria for both substance abuse and history of trauma received Existential Group Art Therapy (EGAT) treatment for eight consecutive weeks. Participants were asked to fill out the Scale for Existential Thinking (SET) at the start of the group and at the end of the treatment process to determine whether or not there was an increase in “existential thinking” following eight weeks of EGAT. The group engaged in the art-making process and discussion of their artwork each week, and were asked to answer Post Group Survey Questions (PGSQ) after the termination of the group. This study details four of the seven participants since they attended most consistently and were deeply engaged in the process. The statistical significance of the observed results was measured using a paired two sample for means T-test (one-tailed). Changes in SET scores were deemed to be statistically significant with a result of p

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Nelson, Brittany L. „Parent-child interaction therapy| A psychoeducational group model for substance using mothers in a residential perinatal substance abuse treatment program“. Thesis, California Southern University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10164042.

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Scope of Study: The scope of this study was to examine the experiences of mothers participating in a pilot program for teaching PCIT skills in a group setting. The importance of the current research is the implementation of a new delivery method of PCIT concepts in a psychoeducational group setting specifically designed for substance using women who do not have the frequency of contact with their children necessary to complete PCIT as it was intended. Developed by the researcher, the PCIT skills group used in this study was a new modality for PCIT treatment to teach the components of PCIT to substance using mothers. The PCIT skills group also included additional educational components including information on how attachments are formed, the impact of substance use on parent-child attachments, the struggles children with attachment problems face, and on repairing attachment problems.

Findings and Conclusions: The purpose of this study was to utilize a newly designed treatment model, a psychoeducational PCIT skills parenting group with an attachment-based focus, with substance using mothers in a residential treatment program in order to assess the potential effectiveness of this treatment delivery model and method. The results demonstrated success in some areas, such as enhancing the understanding of the impact of substance use on the parent-child relationship and increasing knowledge about the importance of meeting children’s emotional needs along with to their physical needs. In addition, some themes not being specifically addressed in the research were represented in the results. The main theme identified was the high presence of guilt experienced by the participants and the influence that guilt has on multiple dynamics within the parent-child relationship. Based on these finding, modifications will be made to the treatment group to incorporate a significant component focusing on guilt along with interventions and techniques to address issues stemming from the guilt.

The results of this study contributed to ideas for further research in regard to substance using mothers and their relationships with their children. More research needs to be conducted in order to further the development of effective attachment-based treatment modality for this population. The results of this study also identified an important need in terms of addressing guilt when working with substance using mothers, as it was identified as highly influential in parent-child attachment, parent-child interactions and in the parents’ ability to implement appropriate parenting interventions with their children.

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Frick, Denise. „Chess as a therapeutic medium in a substance abuse rehabilitation centre a narrative study /“. Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-04302008-080156.

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13

Robertson, Kirsten Renee. „Introducing Shame Resilience to Women who Struggle with Complex Trauma and Substance Abuse“. Antioch University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=antioch1557506178331357.

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14

Fane, Robert. „An Analysis of Substance Abusers' Field Dependence & Time Spent in Rehabilitative Therapy“. TopSCHOLAR®, 1992. https://digitalcommons.wku.edu/theses/2324.

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This project was designed to determine if significant differences existed between the level of psychological differentiation, as determined by the Group Embedded Figures Test (GEFT), of individuals entering a treatment center for chemical dependency and the length of stay at the facility. The subjects consisted of 43 white males who were seeking treatment for addiction to mood altering chemicals at a regional treatment facility in Bowling Green, Kentucky. Each subject was interviewed to collect pertinent background information pertaining to past substance abuse and was evaluated to determine psychological differentiation, utilizing the GEFT. It was determined through an analysis of variance that significant differences did not exist between individuals classified as Field Dependent or Field Independent, relative to length of stay. A post hoc analysis determined that significant differences did exist between those individuals who were categorized as Unclassified (not consistently Field Dependent or consistently Field Independent) and those categorized as Field Dependent and Field Independent.

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Albornoz, Yadira Elizabeth. „THE EFFECTS OF GROUP IMPROVISATIONAL MUSIC THERAPY ON DEPRESSION IN ADOLESCENTS AND ADULTS WITH SUBSTANCE ABUSE“. Diss., Temple University Libraries, 2009. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/38057.

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Music Therapy
Ph.D.
The effect of group improvisational music therapy on depression in adolescents and adults with substance abuse was investigated. It was hypothesized that group improvisational music therapy would relieve depressive symptoms. Twenty-four Spanish-speaking patients receiving outpatient and inpatient treatment for substance abuse at Fundación José Felix Ribas (FJFR), located in Mérida State-Venezuela participated in the study. All participants completed the Beck Depression Inventory (BDI) and the Hamilton Rating Scale for Depression (HRSD) before being randomly assigned to experimental or control groups, each consisting of three cohort groups recruited over a nine month period. The experimental group received 12 group improvisation sessions over a three-month period, along with the standard treatment program provided at the facility, and the control group received only the standard treatment program. Post-test measures were completed at the end of each three-month treatment cycle. Differences between groups in pre-test and post-test scores were calculated using the Mann-Whitney U Test. Results showed that both groups were equally matched on all pretest measures. As for post-test measures, significant differences were found between the groups on HRSD, but not the BDI. The experimental group was significantly less depressed after treatment than the control group, as measured by the HRSD. Improvisational music therapy led to statistically significant greater improvements in psychologist-rated depression (HRSD) when compared to the regular treatment program alone; although no statistical differences were found in the improvements on the BDI between the two treatments, improvisational music therapy had a clinically significant effect. Possible explanations are offered. The most important limitations of the study were the small sample size, absence of a depression assessment tool specifically for substance abuse, and the use of the first version of the BDI instead of the second version as well as lack of information on demographic and clinical data.
Temple University--Theses

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Brakenhoff, Brittany R. „A Thematic Analysis of Substance-Abusing Mothers’ and Their Children’s Discussions during Family Therapy“. The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1353993000.

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17

Cornwall, Jane. „Alcohol dependence and avoidant attachment : implications for therapy“. Thesis, University of Wolverhampton, 2007. http://hdl.handle.net/2436/14641.

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The literature review revealed co-morbidity between adverse childhood experiences, adult psychopathology and alcohol dependence, although causality was questionable due to multiple variables. The current study used 54 clients at the acute end of the spectrum of severe alcohol dependence from a specialist tertiary substance misuse service (clients) and a control group of 54 non-problematic drinkers from an NHS working population (controls) to examine possible differences in security of attachment and maladaptive schemas and investigated how early relational experiences influenced core beliefs regarding self, others and intimate relationships and therapeutic implications for severely alcohol dependent clients’ engagement in specialist services. The study was divided into two sections: (1) quantitative analysis using Feeney, Noller and Hanrahan’s (1994) Attachment Style Questionnaire to measure attachment style and Young’s Schema Questionnaire (Young & Brown, 2001) to measure maladaptive schemas in the domain of disconnection and rejection and (2) qualitative analysis, using Interpretational Phenomenological Analysis (IPA) to explore eight severely alcohol dependent clients’ subjective experiences of intimate relationships. Clients scored significantly lower in secure attachment style and significantly higher in both avoidant and ambivalent attachment style than controls and suggested overlapping between the two dimensions, known as ‘fearful avoidant’ attachment. Clients scored significantly higher than controls in all five sub-categories of maladaptive schemas in the domain of disconnection and rejection, namely mistrust/abuse, emotional deprivation, abandonment, social isolation/alienation and defectiveness/shame. IPA revealed common themes of negative parent-child interaction: physical and psychological abuse, neglect and explicit maternal rejection and emotional deprivation and hostile and abusive parent-parent interaction. These aetiological factors influenced fearful avoidant attachment and maladaptive core beliefs. Negation of children’s needs implicated an immaturely developed diffuseness of identity and defective self that inhibited formation of intimate adult relationships. A bio-psychosocial explanation suggested alcohol ameliorated hyper-vigilant anxiety and depression from adverse childhood experiences within a threatening family environment that implicated insecure attachment, maladaptive core beliefs and negative self-identity, inhibiting emotional intimacy. It advocated screening procedures and an integrated CBT and schema-based therapeutic approach for those at the more severe end of the spectrum of alcohol dependence deemed at risk of not engaging or disengaging prematurely from services.

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Jefferies, Stella Kiah. „Medication-Assisted Therapy Interventions and Prescription Opioid Misuse“. ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/6223.

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Opioid drug misuse and dependence are a social and public health problem in the United States. Prescription opioid abuse and misuse have been associated with substantial morbidity and mortality rates as well as social and economic costs. The purpose of this project was to provide a systematic review of literature on the effectiveness of medication-assisted therapy interventions in addressing the problem of prescription opioid misuse in health care settings. The systematic review was completed through a literature search conducted across five electronic databases. The review was guided by the health belief model and eligible studies were rated using Johns Hopkins hierarchy of evidence. Fifteen peer-reviewed journal articles published from 2011 met the inclusion criteria and were reviewed in full. Of these, 14 were randomized controlled trials and 1 was a quasi-experimental study. The most commonly explored interventions were psychosocial interventions in conjunction with medications for opioid addiction. Review findings provided moderate evidence to support the effectiveness of psychosocial interventions in conjunction with medications in the treatment of opioid dependence, although the strength of the efficacy varied depending on the intervention provided. This project may advance nursing field by promoting provision of care to opioid dependent patients based on the best available evidence. Evidence-based care to patients with prescription opioid dependence will positively impact social change by improving the quality of life of patients, relieving caregivers of the burden of monitoring the addicted patients and saving millions of dollars spent in the criminal justice and health care systems.

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Varra, Alethea A. A. „The effect of acceptance and commitment training on clinician willingness to use empirically-supported pharmacotherapy for drug and alcohol abuse /“. abstract and full text PDF (UNR users only), 2007. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3280752.

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Thesis (Ph. D.)--University of Nevada, Reno, 2007.
"August 2007." Includes bibliographical references (leaves 98-124). Library also has microfilm. Ann Arbor, Mich. : ProQuest Information and Learning Company, [2008]. 1 microfilm reel ; 35 mm. Online version available on the World Wide Web.

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20

Serdencuk, Lauren Amber. „Clinical Director Perspectives on Decision Making of Family Involvement with Clients at Inpatient Substance Abuse Treatment Centers“. Diss., NSUWorks, 2019. https://nsuworks.nova.edu/shss_dft_etd/51.

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Literature supports that family members of individuals who abuse substances are significantly influential, whether it be positive or negative (Liddle et al., 2001). Evidence-based family therapy decreases substance use by adolescents (Slesnick et al., 2006). The purpose of this study was to gain the perspectives of clinical directors regarding decision making of family involvement at inpatient substance abuse treatment centers. Clinical directors were the focus of this study due to their experience, credentials, and their ability to oversee all clients and programs in a substance abuse treatment center. Purposeful sampling was utilized to obtain participants. Saturation was reached at three participants. The study used Thematic Analysis to analyze perspectives of clinical directors and identify themes between and among all participants. The data collection utilized were interviews with clinical directors. The importance of family involvement, factors related to choice of model, and evidence-based models preferred were the main themes discovered utilizing Thematic Analysis. Thematic Analysis exhibited all clinical directors in this study perceived family involvement ‛essential’ and all were not directly in control of decision making regarding family involvement with clients at inpatient substance abuse treatment centers.

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D'Souza, Belinda J. „Deinstitutionalizing Rehabilitation: An Alternative Approach to Rehab for Veterans Suffering from Post-Traumatic Stress Disorder and Substance Abuse Disorder“. University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397734253.

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McKnight, Anne S. „The Examination of Cutoff and Self-Functioning in Three Generations of Families with a Substance-Abusing Teenager“. Diss., Virginia Tech, 2001. http://hdl.handle.net/10919/27524.

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Sixty families who came to a county mental health center for a substance abuse evaluation for a teenager were interviewed. The parent(s) and teenager were administered the Emotional Cutoff Scale, a paper-and-pencil measure. The functioning of each parent was assessed by the researcher through the Global Assessment of Functioning. The child was evaluated on the Child and Family Assessment Scale, an eight dimension scale. Data were gathered and analyzed through a correlational matrix. Significant correlations at P>.01 were found for degree of cutoff of the mother from her mother and father and her level of self-functioning but not with the level of impairment of the teenager. The sample of fathers did not result in significant correlations.
Ed. D.

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Sarvis, Nancy Q., Andrea D. Clements und Tifani A. Fletcher. „Salivary Cortisol Levels of Working Therapy Dogs“. Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/7256.

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Research documenting the level of work-related stress among therapy dogs is limited. This research was designed to measure salivary cortisol in working therapy dogs. Certified handler/dog (Canis lupus familiaris) teams were recruited to participate from teams currently volunteering in the Tri-Cities, Tennessee area. Male and female dogs of various sizes and breeds were recruited. Ten dogs contributed fivesaliva samples. Dogs were fasted for one hour prior to procedure. Samples were collected over a continuum of events, for comparison of salivary cortisol levels in multiple environments. Samples were collected as follows: (1) sample in the dogs’ homes, (1)sample upon arrival at the “work” place, (1) sample just prior to leaving the “work” place, (1) sample just prior to being groomed and (1) sample taken at the dogs’ regular veterinarians’ offices. This design provided 1 control sample, 2 work samples, and2 samples that may be indicative of elevated stress. It was hypothesized that: 1) Salivary cortisol concentrations will be higher in samples collected during grooming and at a veterinary clinic than in samples collected at home, and 2) Salivary cortisol concentrations will be lower in samples collected during “working” conditions than in samples collected during grooming and at a veterinary clinic. Saliva was collected by placing a Salimetrics Children’s Swab (P/N 5001.06) [dimensions 8 x 125 mm] into the dog’s mouth until saturated, or less than four minutes. After examination of the descriptive statistics of (n=10) across five different environmental conditions, it was decided that one of the cases represented an outlier and was removed from data as subsequent analysis revealed a cortisol level that was more than 23 standard deviations away from the mean. Three dogs had at least one sample with insufficient quantity of saliva for analysis, and were removed from the data. A one-way repeated measures ANOVA was conducted to compare salivary cortisol levels during different environmental conditions (pre-therapy, post-therapy, home, veterinary clinic, and groomer). There was not a significant main effect for condition, Wilks’ Lambda =.299, F (9, 2) =1.17, p=.51,multivariate partial eta squared = .70. The hypotheses were not supported. This research suggests that salivary cortisol of working therapy dogs is not significantly different than home, veterinary, or grooming conditions.

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Schmidt, Eric A. (Eric Alexander). „Node-Link Mapping and Rational Recovery: Enhancing the Recovery Process“. Thesis, University of North Texas, 1997. https://digital.library.unt.edu/ark:/67531/metadc277722/.

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Alcoholics Anonymous (AA) continues to be the most accepted approach for the treatment of addictions in the United States. However, due to recent evidence questioning the effectiveness of AA, the need for alternative approaches to the treatment of addictions has become clear. The following research addresses the efficacy of one such alternative, Rational Recovery (RR). Node-Link Mapping (NLM), a graphic communication technique which uses links and nodes as building blocs to facilitate and enhance communication of information as well as awareness in a counseling environment, was implemented to enhance the recovery process. Three groups of ten (10), chemically dependent, adjudicated subjects were exposed to three different treatment approaches at an outpatient counseling center. The Experimental group received RR with NLM, the Comparison group was exposed only to RR, and the Control group continued in treatment according to the protocol of the counseling agency. All subjects were given the Substance Abuse Subtle Screening Inventory-2 (SASSI-2) as a measurement of symptoms associated with chemical dependency. The subjects were also administered the Rotter Internal-External Locus of Control Scale (Rotter I-E Scale) to determine locus of control prior to treatment and any change after treatment.

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Nosal, Yvette D. „Trauma and Addiction: Art Therapy With the Dually Diagnosed Female Client“. Ursuline College / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=urs1208901830.

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Berenschot, David. „A Descriptive Study of the Elderly in California Substance Abuse Treatment Programs“. CSUSB ScholarWorks, 2017. https://scholarworks.lib.csusb.edu/etd/549.

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As gerontologists may know, there are a great deal of studies and a variety of academic literature on the misuse of alcohol and prescription medication amongst the elderly population. While there is a plethora of information on alcohol and prescription misuse, there is little reported data about the prevalence of other substance misuse experienced by this population. This study aims to help to fill that gap in the data by using quantitative methods to describe the scope of substance abuse of individuals 55-years or older. This study utilizes data from the Treatment Data Set Admission (TEDS-A). The TEDS-A is a public data set which includes admissions data from multiple substance abuse treatment facilities associated with the Substance Abuse and Mental Health Services Association (SAMHSA). This is a regional study, therefore this study focuses only on individuals 55-years or older who have been admitted into substance abuse treatment facilities in the state of California in the year 2014. The TEDS-A is a data set that is supported and conducted by members of SAMHSA. Most of their public data sets, including the TEDS-A, can be accessed on their website (https://www.datafiles.samhsa.gov/study/treatment-episode-data-set-admissions-teds-2014-nid16949). The data available in the TEDS-A involves a number of admission questions, including demographic data, reasons for intake, primary through tertiary substance concerns, questions regarding social status, information on medical insurance, and more. This study looks at the descriptive frequencies of the use of alcohol, crack/cocaine, marijuana/hashish, heroin, other opiates & synthetics, methamphetamine, and other substances. The study includes 13,512 cases, of which 9966 (73.8%) of cases were male, 3539 (26.2%) were female, and 7 (0.1%) were missing and/or invalid. The results of the data suggests that, while alcohol abuse is a problem, those over 55 are admitted into substance abuse clinics for many other reasons, not just alcohol abuse.

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Flack, Elizabeth F. „The differential characteristics between transformational change experiences and volitional change in recovering substance dependent individuals“. View electronic thesis, 2008. http://dl.uncw.edu/etd/2008-1/flacke/elizabethflack.pdf.

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Wu, Charlotte Audris. „Qualitative Assessment of Adherence to Antiretroviral Therapy among Chinese Intravenous Drug Users“. Yale University, 2008. http://ymtdl.med.yale.edu/theses/available/etd-08282007-153749/.

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Injection drug users (IDUs) account for an estimated 44% of people living with HIV/AIDS in China and are the major driving force behind the expanding epidemic. Developing effective antiretroviral therapy (ART) adherence interventions in the Chinese IDU population is a major challenge. In conjunction with ART scale-up in Yunnan province, our goal was to gather patient perspectives on ART and ideas for feasible adherence support. Between December 2005 and March 2006, eight focus groups with a total of 55 HIV positive IDUs were conducted at three sites in Yunnan to ascertain ART knowledge, barriers to adherence, and acceptable adherence support methods. Focus groups included ART experienced and naïve participants, and HIV positive IDUs in methadone maintenance clinics. Discussions were audiotaped, notes were transcribed and coded for analyses. All participants were former or current IDUs and 31 were from the rural countryside (59.6%), and 19 (36.5%) resided in a small city. ART was viewed positively but the principal barriers for urban IDUs were stigma and discrimination, while geography was the main problem for rural IDUs. Major themes were stratified between four components: knowledge, motivation, cues to action, and access to care. Adherence tools that were spontaneously endorsed included watches, pill boxes, and diaries. Directly observed therapy (DOT) within methadone programs was acceptable but community-based DOT would need to address stigma issues in urban areas. Two separate HIV epidemics exist within IDUs in China, stratified between small-city urban and rural populations. No single model for adherence will work and interventions must be broad-based. This study provides an expanded conceptual framework for ART adherence in the HIV positive IDU population, which includes the unique barriers posed by the ecological context surrounding this doubly-discriminated population.

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Schwab, Rikki. „Success and Failure of Drug Rehabilitation: Pets Accompanying Clients to Treatment“. ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7254.

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This research addresses the use of canine animals in substance abuse treatment. There is research that addresses the importance of animals regarding therapy and mental illness, as well as research on the comorbidity of severe mental illness and substance abuse disorder. However, there is no research that looks at utilizing canines in substance abuse therapy. The purpose of this research was to examine the utilization of canine animals in rehab for those with substance abuse issues. The theoretical foundation for this study is the theory of contextualism. This theory focuses on humans with animals. To address the gap in research, this quasi-experimental quantitative study looked at two independent variables, presence or absence of a canine during treatment, and gender. The method of data collection was obtaining charts of 130 discharged clients, along with retrieval of data regarding days authorized by insurance for treatment. Information was obtained on the number of days that the client stayed in treatment. There was a comparison of the numbers that created a standardization for treatment. There was not significant difference in the average duration of substance abuse treatment when comparing people who attend treatment with their canine compared to those who do not attend treatment with a canine nor was there a difference between the genders. This research may create positive social change by providing an alternative to substance abuse disorder treatment. Not only will this create a positive environment for the client, but it will also provide them the ability to have comfort in a critical time in their lives. This research shows that canines provide something to mankind that we cannot always provide to one another.

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Jones, Katherine Champe. „Training on the diagnosis, treatment, and referral of substance abusers and their families in AAMFT-accredited master's level marriage and family therapy programs“. Thesis, Virginia Tech, 1989. http://hdl.handle.net/10919/44115.

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Because of the prevalence of substance abuse in America and the association between this issue and common problems brought to the family therapist, it is important that family therapists be trained to diagnose and either treat or refer substance abusing clients and their families. This study gathered information from the Directors of Master's level family therapy programs accredited by AAMFT about the content and format of training that students in their programs receive preparing them to work with substance abusing families. Twenty of the 22 programs were represented by completed questionnaires. Five programs were reported as having a required substance abuse course; four, a popular elective. Three respondents reported plans to increase their coverage of the topic in their curricula.

The average of the responses for prevalence of substance abuse as a central issue in practicum cases was 30%. Although about 75% of the respondents believed that their graduates were ready to diagnose and refer these cases, only 25% believed that these same students were ready to treat substance abuse cases. Data showed that 40% of the respondents believed it advisable for AAMFT to require a separate course on substance abuse. Comments from those opposed to such a requirement noted the crowdedness of existing curricula, the importance of academic freedom, and the abundance of other topics to be covered.
Master of Science

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Davis, Charles N. „Women's Substance Abuse Treatment With Supplemental Couple's Therapy: Changes in Women's Levels of Intimacy and Autonomy in Relation to Treatment Outcomes by Treatment Modality“. DigitalCommons@USU, 2005. https://digitalcommons.usu.edu/etd/2512.

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The current study is a secondary analysis of a National Institute of Drug Abuse (NIDA) study in which 122 women received treatment for their substance abuse problems. Three models of substance abuse treatment were administered. One included standard substance abuse treatment alone and two models included supplemental couple's therapy in addition to standard treatment. The current study examined the significance of the relationship between changes in the women's levels of intimacy and autonomy, during and after treatment, and their treatment outcomes according to the treatment modality they received. It was hypothesized that the relationship would be significant in that levels of intimacy and autonomy would be important variables with regard to treatment outcomes in couple's therapy. No statistical significance was reported although some significant trends were found with regard to the fluctuation of intimacy and autonomy levels during and after treatment. Implications for policy, practice, and future research are reviewed.

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DiMarco, Sandra. „Solution-Focused Family Weekends in an Addictions Treatment Facility: An Action Treatment-and-Research Study“. Diss., NSUWorks, 2019. https://nsuworks.nova.edu/shss_dft_etd/53.

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For the past 69 years, since the start of the addiction treatment system in the United States, treatment providers have been utilizing the same interventions in rehab centers, the majority of which are based on outdated ideas about substance misusers. Though the premise of such interventions has been questioned by researchers, treatment providers continue to utilize them. Family therapy, in particular, shows promising results for substance misusers and their families; it has been cited as the most powerful form of intervention in addiction treatment. Nevertheless, family therapy is underrepresented in the addiction literature and rehab centers. Furthermore, postmodern models of family therapy are even more scarce within these contexts. The purpose of this study was twofold: to explore the viability of an underrepresented, alternative approach to treatment, and to explore the personal, organizational, and clinical processes occurring throughout the development of a systemic family program implemented in an adult inpatient rehab center with an individualistic approach. The researcher modified action research methodology to analyze archival data acquired from a completed clinical project, which was implemented over the course of three weekends. The researcher adapted categorizing and coding procedures from action research in order to analyze 34 personal journal entries and 11 supervision meetings, all of which illuminated the changes in the personal, organizational, and clinical processes that occurred throughout the clinical project. To illustrate the viability of a solution-focused, multiple family group (SFBT-MFG) approach for substance misusers and their families, the researcher collected and analyzed a total of 79 client and family evaluation surveys, 19 pretreatment change questionnaires, and six staff evaluation surveys. The results of this study support an SFBT-MFG approach for adult substance misusers and their families. The researcher identified enhanced communication, understanding, honesty, and support as key themes, along with nine other themes, in the evaluation surveys completed by the participants in the family weekends. The study can help other marriage and family therapists undergo their own processes of integration when practicing systemically in a culture guided by individualistic notions of mental health.

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Howell, Rachel J., Michael K. Schiferl und Lauren Ph D. Ruhlmann. „Barriers Sex Trafficking Survivors Encounter during the Transition out of Commercial Exploitation“. Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/secfr-conf/2019/schedule/11.

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Survivors of sex trafficking report numerous intrapersonal, interpersonal, and contextual challenges which likely play a role in their transition out of commercial sexual exploitation. The purpose of this phenomenological study was to begin investigating survivors’ perceptions of the transition process, namely barriers they encounter along the way. Researchers facilitated semi-structured qualitative interviews with six survivors enrolled in a residential recovery program. Analyses yielded two themes: 1) intrapersonal barriers and 2) service barriers. Intrapersonal barriers included codes such as emotional control, self-perception, addiction, and mental health. Service barriers included codes related to specialized professional support, non-professional support, tangible resources, and intangible resources. This poster will provide an overview of themes and codes, as well as a description of the practical significance of the study results. Findings have important implications for the broader understanding of sex trafficking survivor needs during a particularly vulnerable point in their long-term recovery process.

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Robinson, Charlotte E. Ms. „Preventing Post - Treatment Relapse among African American Adolescents and Young Adult Marijuana Users through Effective Treatment Interventions: A Proposed Intervention for Metro-Atlanta“. Digital Archive @ GSU, 2013. http://digitalarchive.gsu.edu/iph_theses/293.

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INTRODUCTION: Marijuana use, although illegal in the majority of states, is increasingly becoming acceptable for use in the United States. There are dangerous public health consequences associated with marijuana use—including: impaired driving, loss of productivity in workplaces and school settings, as well as mental health impacts. In Atlanta, the majority of residents (54.0%) are African American. Emergency room use is double for African American Fulton County residents compared to their Caucasian counterparts and approximately 1/5 of the total population receiving public health treatment identify marijuana as the primary drug of use, with 57% of those being African Americans. Despite these statistics, the availability of treatment and prevention programs targeting African Americans using marijuana is negligible.AIM: The purpose of this study is to synthesize evidence-based approaches to substance use treatment so that effective components of previous research can be incorporated into an innovative marijuana prevention program to increase post-treatment abstinence targeting a segment of the population that has not been a significant focus in intervention research. METHODS: A review of scientific literature was conducted to identify and appraise evidence based approaches to substance use among young adults. First, the student researcher examined programs targeting marijuana use. Second, the search was expanded to substance use in general. The student researcher identified the population, intervention, control arm, and outcomes of various studies focusing on substance use prevention in a variety of settings. With this appraisal, the most effective components are suggested for a marijuana specific program which could be offered to African-American young adults, as no current programs in Georgia were found. RESULTS: Substance abuse intervention approaches targeting young adult populations were identified. Programs are delivered in a variety of settings: family, school, and community. Evidence supports that cognitive behavioral training, motivational enhancement training, and contingency management are the most effective approaches targeting substance use among young adults. A program that integrates components of each approach would be ideal for targeting African American young adults using marijuana in Metro-Atlanta and assisting them to maintain abstinence post-treatment. DISCUSSION: The results from this study emphasize key program elements that can address marijuana addiction among African American young adults in Metro-Atlanta. As marijuana acceptance increases, the need for prevention programs becomes more urgent. This study’s results can assist program planners in understanding the most strategic interventions that would optimize return on investment when addressing a largely silent public health threat: marijuana use among Africa American young adults in Metro-Atlanta.

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Krebs, Kathleen A. „Art Therapy Used to Enhance Steps One, Two and Three of a Twelve-step Recovery Program for Addictions Treatment“. Ursuline College / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=urs1210866880.

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Maloney, Susan Margret. „Occupational performance of collegiate high-risk drinking as a serious leisure hobby“. Thesis, NSUWorks, 2008. https://nsuworks.nova.edu/hpd_ot_student_dissertations/3.

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The purpose of this grounded theory qualitative study was to examine the experiences of college students who defined themselves as high-risk drinkers in order to understand the meaning and purpose that engagement in such a leisure occupation held for them. By examining the world of high-risk drinking, the study also sought to develop an understanding of the impact that high-risk drinking had upon psychosocial development during the college years. Individual open-ended interviews were conducted with four male and four female participants (aged 21 to 27). The data were analyzed by three analysts utilizing constant comparative procedures. The findings revealed an emergent grounded theory indicating high-risk drinking adhere to the serious leisure hobby framework developed by Stebbins (2007). As such, the participants had a long-term time investment with drinking, developed special skills through sustained effort, solidified a unique identity as a hobbyist, found deep meaning and purpose through the hobby, and performed the hobby within a unique and special world in concert with other hobbyists. Their high-risk drinking provided structure and a sense of belongingness within the larger university context. Further, the findings indicate that across time, facilitating factors catalyzed their engagement in the hobby, while the moderating factors became less influential. The participants also believed that their highrisk drinking will easily diminish post-graduation merely by changing their life role and context. iv Envisioning high-risk drinking as a serious leisure hobby, rather than a psychiatric or medical disorder, provides an alternative framework upon which prevention and intervention programming may be focused. Occupational therapist could provide an important health care role on campuses by assisting students to (a) understand the factors underlying the appeal of high-risk drinking, (b) understand the implications that a restricted range of leisure occupations may have upon their health, psychosocial development, and occupational identity, and (c) explore alternative health-producing leisure occupations.

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Stennett, Bethany Ann. „Novel Therapy for Nicotine Addiction in Alcohol Dependent Rats“. UNF Digital Commons, 2013. http://digitalcommons.unf.edu/etd/465.

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The co-dependence of nicotine and alcohol addiction occurs at high rates, complicates treatment, and is often associated with significant morbidity and mortality. Treatment options of alcohol and tobacco co-dependence are limited. Currently, there are drugs available for nicotine dependence or alcohol dependence. However, there are no therapeutic drugs available on the market for the co-dependence of nicotine and alcohol. Therefore, and important opportunity of new therapeutic options and drug development has presented itself. NT69L, a non-selective neurotensin (NT) agonist, provides a potential novel therapy for nicotine addiction in alcoholics by interacting with the common neurotransmitter circuits supporting the rewarding process for both nicotine and alcohol. Considering the behavioral effects of NT69L in attenuating nicotine self-administration in rats and alcohol consumption in mice, the present study was designed to assess the effects of NT69L as a new drug. NT69L was used in the treatment of nicotine addiction in an animal model of alcoholics and in attempts to attenuate withdrawal signs associated with nicotine and alcohol dependence. Wistar rats pre-exposed to alcohol vapor or air were allowed to self-infuse nicotine (0.03mg/kg/infusion) or saline. When the rats reached a stable level of responding, the effect of pretreatment with NT69L (1mg/kg i.p.) on the reinforcing effect of nicotine was determined. Animals self-infused nicotine at a significantly (p < .05) higher rate compared to saline in both air and alcohol vapor exposed groups. Acute pretreatment with a single injection of NT69L significantly (p < .05) reduced nicotine self-infusion in both the alcohol vapor and the air exposed groups for 5 days post-injection. Additionally, NT69L attenuated the alcohol- and nicotine-induced withdrawal signs associated with the discontinuation of alcohol and nicotine administration. Neurotensin agonist, NT69L, may represent a potential novel therapy to treat the co-addiction of alcohol and nicotine.

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Dunlap, Amy L. „Women with Addictions' Experience in Music Therapy“. Ohio University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1483647124948226.

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Clarfield, Cynthia E. clarfield. „“You’re Doing Fine, Right?”: Adolescent Siblings of Substance Abusers“. Antioch University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=antioch1506194801004877.

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Helbig, Friederike, Anja Pixa, Gerhard Bühringer und Jürgen Hoyer. „Wirksamkeit ambulanter Verhaltenstherapie bei Substanzstörungen und abhängigen Verhaltensweisen - Evaluation einer Spezialambulanz“. Karger, 2017. https://tud.qucosa.de/id/qucosa%3A71680.

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Hintergrund: Die Psychotherapierichtlinien ermöglichen erst seit 2011 unter bestimmten Bedingungen eine ambulante psychotherapeutische Behandlung bei Substanzstörungen. Empirische Ergebnisse zu diagnostischen Charakteristika der auf dieser Grundlage behandelten Patienten und zu Erfolgsraten fehlen weitgehend. Methoden: Wir untersuchten N = 59 konsekutive Patienten einer Spezialambulanz, von denen n = 34 eine Behandlung begannen (Intent-to-Treat(ITT)-Stichprobe) und n = 28 sie abschlossen (Completer), mit standardisierten diagnostischen Interviews und ermittelten die Erfolgsraten nach ambulanter Kognitiver Verhaltenstherapie (Einzeltherapie) auf der Basis von Symptomskalen (Brief Symptom Inventory (BSI); Beck Depression Inventory (BDI)) sowie Patienten- und Therapeuten-Ratings, einschließlich einer klinischen Beurteilung der Abstinenz. Ergebnisse: 40% aller anfragenden Patienten nahmen keine Psychotherapie auf. Bei den behandelten Patienten kam es zu signifikanten Veränderungen (ITTAnalysen: d = 0,8 (BSI) bis d = 1,2 (BDI)). Mehr als zwei Drittel der Patienten erreichten eine klinisch relevante Verbesserung der Symptomatik gemäß Patienten- oder Therapeutenbeurteilungen (zwischen 68 und 76%, ITTStichprobe). Alle Completer mit Abhängigkeitssyndrom (n = 11) sowie 86% der diesbezüglichen ITT-Stichprobe erreichten zumindest unter der Behandlung eine Abstinenz. Schlussfolgerungen: Die Erfolgsraten bei Patienten, die die Therapie abschließen, sind gut. Sie sprechen für den Nutzen des ambulanten Settings.
Effectiveness of Outpatient Cognitive-Behavioral Therapy for Substance Use Disorders – Evaluation of a Specialized Outpatient Clinic Background/Aim: Given a number of conditions, the revision of the German psychotherapy guidelines in 2011 facilitates treating substance use disorders in outpatient psychotherapy. Empirical results on the diagnostic characteristics of the patients treated within this setting and about the effectiveness of the treatment are lacking. Material and Methods: We examined N = 59 consecutive patients, diagnosed with standardized diagnostic interviews, of a specialized outpatient clinic for cognitivebehavioral therapy. Of these, n = 34 started the treatment (intent-to-treat (ITT) sample) and n = 28 completed it. The outcome (including clinical judgement of abstinence) was assessed with established symptom scales (Brief Symptom Inventory (BSI), Beck Depression Inventory (BDI)) as well as therapist and patient ratings. Results: About 40% of the patients who contacted the clinic did not start the therapy. In therapy completers, clinically relevant improvement was reached. Based on ITT analyses, effect sizes ranged from d = 0.8 (BSI) to d = 1.2 (BDI). Based on therapist and patient ratings, the percentage of successful therapies was high (between 68 and 76%, ITT analyses). All therapy completers diagnosed with a dependence syndrome reached abstinence at least temporarily. Conclusion: Effectiveness rates are high in completers. These results show that treatment can be efficient in an outpatient setting.

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Khachatryan, Sunny Nelli. „Family Therapist Connecting and Building Relationships with Substance Abusers in the Seminole Tribe of Florida: An Ethnographic Study“. NSUWorks, 2015. http://nsuworks.nova.edu/shss_dft_etd/8.

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The purpose of this ethnographic study was to examine the process of a family therapist entering and then navigating the cultural system of working with substance abusing Seminole tribal clients. The study also utilized two tribal members sharing their opinions about how Seminoles view therapy. As noted in the interview questions and responses, the research presented guidelines for family therapists to follow when working with tribal members. Because there has been no study conducted with family therapists providing clinical services to tribal members, this study introduced tools for clinicians to keep in mind and utilize when working with tribal clients. The interviews illustrated what specific routes therapists may take with tribal clients in order to join and connect. This study provided the field of family therapy an opportunity to become familiar with the Seminole tribe, and guidelines of how to remain mindful when working with this unique population. These results were supplemented by the researcher providing personal reflections on her experiences with tribal clients.

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Zhang, Ting. „DEVELOPMENT AND PRECLINICAL EVALUATION OF LONG-LASTING COCAINE HYDROLASES FOR COCAINE OVERDOSE AND COCAINE USE DISORDER TREATMENT“. UKnowledge, 2018. https://uknowledge.uky.edu/pharmacy_etds/93.

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Cocaine is a plant-based illicit drug commonly involved in substance use disorder. Although cocaine overdose and cocaine use disorders cause adverse health consequences to individuals and the economic burden on their family and society, there are no FDA (Food and Drug Administration) approved medications for treatment. Recently, it has been recognized that delivery of cocaine hydrolase (CocH) is a promising therapeutic strategy. Human butyrylcholinesterase (hBChE), the primary enzyme involved in cocaine metabolism in human, have advantages over other candidates for the development of CocH. Previous studies in our laboratory have designed and characterized hBChE mutants that have ~4,000-fold improved catalytic efficiency against naturally occurring (-)-cocaine as compared to the wild-type hBChE. Besides the catalytic efficiency, the biological half-life is another essential factor that influences the desired therapeutic value in the long-term treatment of cocaine use disorder. In order to provide prolonged effects to reduce administration frequency in clinical use, efforts have been made to increase the retention time of CocHs in blood circulation by fusing CocHs with other thermostable proteins or their mutants, including human serum albumin (Albu) or the Fc region of the human IgG (Fc). In this dissertation, we demonstrated the clinical potential and the benefits of long-lasting CocHs for cocaine overdose treatment. We used rodent models to show the ability of AlbuCocH1 to block or reverse manifestations of toxic effects of cocaine. In addition, a concomitant LC-MS/MS-based analysis was conducted to investigate the pharmacokinetic profile of a lethal dose of cocaine with the presence of AlbuCocH1. These experimental data demonstrated AlbuCocH1 as an effective cocaine detoxification agent by accelerating the metabolism of cocaine. In order to examine the potential therapeutic value of Fc-fused CocHs in the treatment of cocaine use disorder, we conducted a series of behavioral experiments in rats to evaluate the effectiveness and duration of Fc-fused CocHs in blocking or attenuating cocaine-induced psychostimulant and discriminative stimulus effects. In addition, the intravenous self-administration model was used to investigate the long-term effectiveness of Fc-fused CocHs in blocking or attenuating the reinforcing effects of cocaine. It has been shown that a single dose of E30-6-Fc (3 mg/kg) was able to effectively alter the cocaine dose-response curve and attenuate the reinforcing efficacy of cocaine for at least a month in both male and female rats. In summary, AlbuCocH1 (TV-1380), which failed to meet the primary efficacy endpoint in clinical trials for facilitating abstinence in cocaine-dependent subjects with a weekly dosing schedule (due to the short biological half-life), is more suitable to be developed as a cocaine detoxification agent. On the contrary, the newly designed Fc-fused CocH (e.g. CocH3-Fc, E30-6-Fc) with higher catalytic efficiency and longer biological half-life will be beneficial for long-term abstinence management in cocaine-dependent individuals.

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Mutiso, Lori A. „Factors Influencing Depression in Men: A Qualitative Investigation“. UKnowledge, 2015. http://uknowledge.uky.edu/nursing_etds/15.

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The purpose of this qualitative descriptive study is to describe men’s experiences of depression in order to provide direction for future research of the screening, diagnosing, and treatment of men's depression. Previous research indicates that men experience different depressive symptoms than women, and there is a possibility that men's depression is not being adequately captured by current screening standards, which would theoretically lead to a large number of men with unrecognized, undiagnosed, and untreated depression. If this is the case, this may explain the disproportionately low number of men diagnosed with depression compared to women, in contrast to the disproportionately high number of men who complete suicides. There is a need in the literature for descriptions of depression experienced by men in order to determine the adequacy of current psychometric screening tools and approaches to treatment which are currently in practice. This qualitative study seeks to begin to fill in this gap in the literature. Key findings indicate that intentionally and unintentionally hide their feelings of depression, and that men experience anger as an early sign of depression. In addition, men often do not recognize their distress as depression until someone else suggests they seek professional help; and men use various methods of distraction to cope with their distress, including excessive working, sleeping, eating, TV watching, and alcohol consumption. Recommendations for further research are discussed.

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Forrest, Gary Miles. „Attachment, Anxiety, and Depression| A Study of Women in Residential Treatment with their Children at the Susan B. Anthony Recovery Center (SBARC) (1995-2010)“. Thesis, Nova Southeastern University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3680549.

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The Susan B. Anthony Recovery Center (SBARC) in Pembroke Pines, Florida is a residential center where women live with their children while receiving treatment for a variety of co-occurring substance abuse and mental health issues and while participating in mandatory parenting classes. Unlike most women's residential treatment centers, which address only the woman and her problems, SBARC treats the mother-infant/child dyad. I designed and created a database to examine the data previously available only in the paper client records of over 800 women who received treatment at SBARC from 1995 through 2010 in a previous project. This nonexperimental, retrospective explanatory study (Johnson, 2001; Johnson & Christensen, 2014) analyzed that newly digitized historical data to examine the efficacy of the SBARC treatment with respect to three key variables: dyadic attachment, maternal anxiety, and maternal depression (N = 268). Correlational analysis (MANOVA) of the three variables showed significant results, which suggest that reductions in maternal anxiety and maternal depression may be related to increases in the quality of the dyadic attachment. Statistical analysis (ANOVA) found significant increases in dyadic attachment and decreases in maternal anxiety and maternal depression. The results of this nonexperimental study support the need for future research via controlled studies to determine the relationships among these key treatment variables. Grossmann, Grossmann, and Waters (2005) and others claim that improvement in dyadic attachment improves outcomes for children. Dodge, Sindelar, and Sinha (2005) and others also believe that reductions in maternal depression and maternal anxiety may result in better outcomes. The results of this study suggest that there is value in combining these two perspectives so that measurements of dyadic attachment, maternal anxiety, and maternal depression inform future program offerings and treatment plans. The multi-disciplinary foundation of attachment theory and its rich offering of systemic and relational therapy approaches provides what I believe may be an effective blend of treatment options supported by useful empirical measures that can greatly enhance and expand professional competencies of Marriage and Family Therapists involved in clinical practice with similar at-risk populations.

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Vilela, Fabiana Andrioni de Biaze [UNIFESP]. „Fatores preditivos de Aderência no tratamento de usuários de maconha“. Universidade Federal de São Paulo (UNIFESP), 2011. http://repositorio.unifesp.br/handle/11600/9646.

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Made available in DSpace on 2015-07-22T20:50:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-11-24. Added 1 bitstream(s) on 2015-08-11T03:26:09Z : No. of bitstreams: 1 Publico-12675.pdf: 644045 bytes, checksum: 4760c174c211a52ff1a44e954522d1af (MD5)
A aderência ao tratamento para dependência química é questão preocupante e requer atenção especial dos profissionais que atuam com esta população. OBJETIVO: identificar características dos pacientes usuários de maconha que possam ser consideradas fatores preditivos de abandono do tratamento. METODOLOGIA: foi realizada a análise secundária dos dados de um Ensaio Clínico Randomizado em que foram incluídos 169 dependentes de maconha avaliados no ingresso e reavaliados três vezes nos seguimentos realizados após o tratamento breve ao qual foram submetidos. Os pacientes foram randomizados em três grupos de tratamento: no Grupo 1, os pacientes foram submetidos a quatro sessões de tratamento em um mês, no Grupo 2, as mesmas quatro sessões em três meses e no Grupo 3 ficaram os pacientes em espera, os quais, posteriormente foram randomizados para um dos dois grupos de tratamento. RESULTADOS: Os pacientes alocados no grupo três, ou seja, de espera, apresentaram 3.47 vezes mais chance de abandono do que aqueles inseridos nos outros grupos. Baseado nos dados sócio demográficos, concluiu-se que para cada ano de idade do paciente, as chances de abandono poderiam ser multiplicadas por 0,91, representando riscos mais baixos. Para cada ano de consumo da maconha, as chances também seriam multiplicadas por 0,92 representando menores riscos. CONCLUSÃO: Diante dos dados obtidos, pode-se inferir que quanto mais velho e quanto mais anos de consumo de maconha o sujeito tem, menores são suas chances de desistência do tratamento. Desta forma, pode-se apontar a importância de intervenções específicas para os grupos com riscos mais altos de abandono do tratamento foi discutida bem como a relevância de outros estudos envolvendo usuários de maconha e indicações para os profissionais ajudarem os pacientes a aderirem ao programa proposto.
The present study involved secondary analysis of data from a Randomized Clinical Trial including 169 cannabis-dependents not only dependents assessed at baseline and submitted to brief treatment. Patients were first randomized into three treatment groups. OBJECTIVES: The objective was to identify characteristics which could be considered predictors of treatment dropout. RESULTS: Patients initially allocated into the control group presented a 3.47 greater chance of drop out than those of the treatment groups. Based on the socio-demographic data, it was concluded that for every year of patient age, the chances of drop out would be multiplied by 0.91, representing lower risk. For every year of cannabis use, chances of drop out would be multiplied by 0.92, again representing reduced risk. CONCLUSIONS: The importance of specific interventions for groups with a higher risk of treatment drop out was discussed, along with the relevance of other studies involving cannabis users and possible guidelines for professionals help patient to adhere.
TEDE
BV UNIFESP: Teses e dissertações

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Gomez-Gillard, Patricia Miriam. „Constructivist research project needs assessment of rural drug court clients: A case study“. CSUSB ScholarWorks, 2002. https://scholarworks.lib.csusb.edu/etd-project/2110.

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Armstrong, Jennifer B. „Loneliness and Perceived Stigmatization Among Older Adults Enrolled in Opiate Substitution Treatment Programs and the Utilization of Mental Health Services“. Antioch University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=antioch1440508405.

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Ellison, Cassandra J. „Recovery From Design“. VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4884.

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Through research, inquiry, and an evaluation of Recovery By Design, a ‘design therapy’ program that serves people with mental illness, substance use disorders, and developmental disabilities, it is my assertion that the practice of design has therapeutic potential and can aid in the process of recovery. To the novice, the practices of conception, shaping form, and praxis have empowering benefit especially when guided by Conditional and Transformation Design methods together with an emphasis on materiality and vernacular form.

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Rosa, Sandro Santos da. „Musicoterapia e cuidado humano: a música e a reabilitação de pessoas que fazem uso abusivo de substância psicoativas“. Faculdades EST, 2013. http://tede.est.edu.br/tede/tde_busca/arquivo.php?codArquivo=458.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico
A utilização da música na reabilitação de pessoas que fazem uso abusivo de substâncias psicoativas configura-se como uma incógnita epistemológica para o campo da musicoterapia. A carência de pesquisas teóricas e práticas no âmbito da musicoterapia, que atentem para a complexidade da demanda na reabilitação de pessoas acometidas pelo abuso de substâncias, é o principal motivador para a elaboração do trabalho. Sendo metodologicamente provindo de revisão bibliográfica, o escrito é divido em três momentos. O primeiro investiga de que maneira o uso abusivo de substâncias psicoativas arraigou-se como um dos principais problemas da sociedade atual e de que forma o uso de substâncias está culturalmente relacionado às artes, especificamente a música. Servirão de aporte para essa parte, os olhos da Teologia da Libertação, a qual busca no âmago do sofrimento das pessoas, o reconhecimento da dignidade inerente a todos os seres humanos. A identificação das vias rituais pelas quais acontece a trans-significação do real pelo ser humano, é executada no segundo momento. Questões relacionadas às linguagens e às formas pelas quais o ser humano sai da realidade, as quais intermediam suas buscas existenciais, são o cerne dessa parte. O terceiro e último momento avista a natureza comunicacional e organizacional da música, para uma formulação epistemológica que contemple a demanda concernente à prática clínica musicoterapêutica na reabilitação de pessoas acometidas pelo abuso de substâncias. Identifica-se nessa parte, que a sessão musicoterapêutica é uma prática salutar de trans-significação do devir humano.
The use of music in rehabilitation of people who use psychoactive substances emerges as an epistemological question to the field of Music Therapy. The lack of theoretical and practical researches in Music Therapy, which focuses on the complexity of the demand in rehabilitation of people affected by the abuse of substances, is the main motivator for the development of this work. Methodologically based on a bibliographical review, this dissertation is divided into three parts. The first investigates how the abuse of psychoactive substances rooted itself as one of the main problems of the current society and how the use of substances is culturally related to the arts, specifically music. This part has an approach of the Liberation Theology, which seeks the recognition of the dignity, common to all human beings, by looking into the suffering of the people. The second part identifies the ritual paths, in which the trans-signification of what is real happens. Issues related to language and ways the human being uses to leave reality, which mediate their existential quest, are the core of this part. The third and last part addresses the communicational and organizational nature of the music, in order to build an epistemological concept that considers the demand regarding to the clinical music therapy practice in rehabilitation of people affected by the abuse of substances. In this part, we identify that the Music Therapy session is a healthy practice of trans-signification of becoming human.

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Fonseca, Casals Francina. „Pharmacogenomic study of oppioid addicts in methadone treatment / Francina Fonseca Casals“. Doctoral thesis, Universitat Pompeu Fabra, 2010. http://hdl.handle.net/10803/7234.

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Although the well established efficacy of methadone maintenance treatment (MMT) in the opioid dependence disorder, there is a group of patients that are poor responders. The study of the influence of methadone pharmacodynamics and pharmacokinetics in dose requirements and program outcome remains still controversial. The aim of this dissertation is to study the pharmacodynamic and pharmacokinetic factors involved in the methadone maintenance treatment efficacy.
The study recruited opioid dependence patients (DSM-IV criteria) from a MMT community program. Patients were clinically assessed and blood samples were obtained in order to evaluate methadone plasma concentrations of (R,S)-, (R) and (S)- methadone. Allelic variants of genes encoding the following proteins were assessed: BDNF, OPRM1, MYOCD, mGluR6, mGluR8, CRY1, NR4A2, 1q31.2 (rs965972), 2q21.2 (rs1867898), CYP3A5, CYP2D6, CYP2B6, CYP2C9, CYP2C19 and P-glycoprotein. Responders and non-responders were defined by means of illicit opioid consumption detected in random urinalyses.
Differences in response status were found depending on different single nucleotide polymorphisms (SNPs of genes encoding for BDNF, MYOCD and GRM6. The CYP2D6 metabolizing phenotype was associated with response to MMT, and also with methadone dosage requirement and methadone plasma concentrations.
Els programes de manteniment amb metadona (PMM) han demostrat eficàcia en el tractament del trastorn per dependència d'opiacis malgrat la persistència de pacients amb mala resposta al tractament. L'estudi dels factors farmacodinàmics i farmacocinètics implicats en la resposta terapèutica ofereix resultats controvertits. L'objectiu de la tesi doctoral que es presenta és estudiar els factors farmacodinàmics i farmacocinètics de la metadona que poden estar implicats en l'eficàcia del tractament. S'han inclòs pacients ambulatoris diagnosticats de trastorn per dependència d'opiacis (segons criteris DSM-IV) en PMM. Els pacients s'han avaluat a nivell clínic i s'han obtingut mostres de sang per a l'estudi de les concentracions plasmàtiques de (R,S)-, (R) i (S)- metadona. S'han estudiat també les variants al·lèliques dels gens que codifiquen per: BDNF, OPRM1, MYOCD, mGluR6, mGluR8, CRY1, NR4A2, 1q31.2 (rs965972), 2q21.2 (rs1867898), CYP3A5, CYP2D6, CYP2B6, CYP2C9, CYP2C19 i P-glicoproteïna. La mostra s'ha dividit en responedors i no responedors en funció del nombre de controls d'orina positius per a heroïna en analítiques realitzades de forma aleatòria.
Es van detectar diferències en resposta al tractament segons les variants dels gens codificants per a BDNF, MYOCD i GRM6. També es va detectar una associació entre el fenotip de CYP2D6, la resposta al tractament, la dosi requerida de metadona i les concentracions plasmàtiques.

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