Auswahl der wissenschaftlichen Literatur zum Thema „Structural parameter of refractive index“

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Zeitschriftenartikel zum Thema "Structural parameter of refractive index"

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Prajapati, A. N. „Study of Molecular Interaction in Binary Mixtures (1-Propanol + Acetophenone)“. Advanced Materials Research 1141 (August 2016): 125–30. http://dx.doi.org/10.4028/www.scientific.net/amr.1141.125.

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Studies on Physico-chemical properties of binary liquid mixtures provide information on the nature of interactions between the constituent of the binaries. Literature provides extensive data on the static dielectric constant (ε0) and refractive index (n) of liquid compounds, but the combined study of all is quite scarce. In the present work static dielectric constant (ε0) and refractive index (n) have been experimentally determined for binary liquid mixture of 1-Propanol (PrOH) with Acetophenone (ACP) over the entire concentration range of mixture composition (0.0 →1.0) at constant temperature 303 K. Static dielectric constant (ε0) and refractive index (n) for the binary mixture have been measured using high precision LCR meter (0.2 MHz) and Abbe’s refractometer respectively. Excess of static dielectric constant (ε0)E and refractive index (n)E are determined and fitted with Redlich-Kister polynomial equation to derive the binary coefficients and standard deviations. For interaction and structural information various parameters namely, Kirkwood correlation factor (g), Kirkwood effective correlation factor (geff), Kirkwood angular correlation factor (gF) and Bruggeman parameter (fB) are determined for the binary mixtures. Variations of these parameters against the concentration of constituents are discussed in terms of molecular interaction between the constituent species.
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Yu, Jing, Tingting Lang und Huateng Chen. „All-Metal Terahertz Metamaterial Absorber and Refractive Index Sensing Performance“. Photonics 8, Nr. 5 (14.05.2021): 164. http://dx.doi.org/10.3390/photonics8050164.

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This paper presents a terahertz (THz) metamaterial absorber made of stainless steel. We found that the absorption rate of electromagnetic waves reached 99.95% at 1.563 THz. Later, we analyzed the effect of structural parameter changes on absorption. Finally, we explored the application of the absorber in refractive index sensing. We numerically demonstrated that when the refractive index (n) is changing from 1 to 1.05, our absorber can yield a sensitivity of 74.18 μm/refractive index unit (RIU), and the quality factor (Q-factor) of this sensor is 36.35. Compared with metal–dielectric–metal sandwiched structure, the absorber designed in this paper is made of stainless steel materials with no sandwiched structure, which greatly simplifies the manufacturing process and reduces costs.
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Ciocirlan, Oana, und Olga Iulian. „Density, viscosity and refractive index of the dimethyl sulfoxide + o-xylene system“. Journal of the Serbian Chemical Society 74, Nr. 3 (2009): 317–29. http://dx.doi.org/10.2298/jsc0903317c.

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This work reports the experimental results of the densities, viscosities and refractive indices between 298.15 and 323.15 K of the dimethyl sulfoxide + o-xylene system over the entire composition range of the mixtures. The excess molar volumes (VE), viscosity deviations (?v), excess Gibbs energy of activation of viscous flow (G*E) and deviations in the refraction (?R) were calculated from the experimental data; all the computed quantities were fitted to the Redlich-Kister equation. The system exhibits moderate negative values for the investigated excess properties. The resulting excess functions were interpreted in structural and interactional terms. From the experimental data, the thermodynamic functions of the activation of viscous flow were estimated. The viscosity data were correlated with several semi-empirical equations. The two-parameter McAllister equation can give very good results.
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Hussein, Ahang M., Elham M. A. Dannoun, Shujahadeen B. Aziz, Mohamad A. Brza, Rebar T. Abdulwahid, Sarkawt A. Hussen, Sarkawt Rostam, Dalia M. T. Mustafa und Dana S. Muhammad. „Steps Toward the Band Gap Identification in Polystyrene Based Solid Polymer Nanocomposites Integrated with Tin Titanate Nanoparticles“. Polymers 12, Nr. 10 (10.10.2020): 2320. http://dx.doi.org/10.3390/polym12102320.

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In the current study, the film fabrication of polystyrene (PS) based polymer nanocomposites (NCs) with tuned refractive index and absorption edge was carried out using the solution cast method. X-ray diffraction (XRD) and ultraviolet-visible (UV-Vis) light characterization techniques were performed. The structural and optical properties of the prepared films were specified. The hump of PS decreased significantly when SnTiO3 nanoparticles (NPs) were introduced. Sharp and high intense peaks of SnTiO3 NPs at a high filler ratio were observed. The crystalline size was determined for SnTiO3 NPs from the sharp crystalline peaks using Debye-Scherrer’s equation and was found to be 25.179 nm, which is close enough to that described by the supplier. Several optical parameters, such as absorption coefficient (α), refractive index (n), and optical dielectric properties, were investigated. The absorption spectra were tuned with increasing SnTiO3NPs. Upon the addition of the NPs to the PS host polymer, the absorption edge undergoes shifting to lesser photon energy sides. The optical dielectric constant (ε′) was correlated to the refractive index. The study of the optical band gap was conducted in detail using both Tauc’s model and the optical dielectric loss (ε″) parameter. The results showed that the ε″ parameter is noteworthy to be measured in the optical band gap study of materials.
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Liu, Yan Jun, und Tong Dai. „Investigation on Dispersion Property of a Novel Photonic Crystal Fiber with Square Array Air Holes“. Advanced Materials Research 571 (September 2012): 278–82. http://dx.doi.org/10.4028/www.scientific.net/amr.571.278.

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The dispersion property of a novel photonic crystal fiber with square array air holes was simulated with the vectorial beam propagation method. The impacts of the pitch and hole diameter on the effective area of fundamental mode and the dispersion parameter were evaluated. The results indicate that the effective refractive index decreases and the dispersion parameter increases with air hole diameter increasing and the pitch decreasing, the structure parameters of inner three rings air hole influences the dispersion characteristics greatly. Thus the dispersion property of the photonic crystal fiber can be tailed by the structural parameters.
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Sakiroglu, S. „Linear and nonlinear optical absorption coefficients and refractive index changes in Morse quantum wells under electric field“. International Journal of Modern Physics B 30, Nr. 30 (23.11.2016): 1650209. http://dx.doi.org/10.1142/s021797921650209x.

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In this paper, we investigate theoretically the effects of electric field on the linear and nonlinear optical properties of Morse quantum wells considering a two-level system. The effective mass approximation and the envelope function approach are used to calculate the energy levels and wave functions. The analytical expressions of the optical properties are obtained by using the compact density-matrix approach. The linear and third-order nonlinear optical absorption coefficients and the refractive index changes are investigated as a function of the incident photon energy for several configurations of the structural parameter and the applied electric field. Numerical results, presented for a typical GaAs/AlGaAs quantum well, reveal that the electric field has a significant effect on the optical characteristics of these structures and intersubband transitions can be modified by tuning the structural range parameter of the potential.
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Aziz, Shujahadeen B., Elham M. A. Dannoun, Dana A. Tahir, Sarkawt A. Hussen, Rebar T. Abdulwahid, Muaffaq M. Nofal, Ranjdar M. Abdullah, Ahang M. Hussein und Iver Brevik. „Synthesis of PVA/CeO2 Based Nanocomposites with Tuned Refractive Index and Reduced Absorption Edge: Structural and Optical Studies“. Materials 14, Nr. 6 (23.03.2021): 1570. http://dx.doi.org/10.3390/ma14061570.

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In the current study, polymer nanocomposites (NCPs) based on poly (vinyl alcohol) (PVA) with altered refractive index and absorption edge were synthesized by means of a solution cast technique. The characterization techniques of UV–Vis spectroscopy and XRD were used to inspect the structural and optical properties of the prepared films. The XRD patterns of the doped samples have shown clear amendments in the structural properties of the PVA host polymer. Various optical parameters were studied to get more insights about the influence of CeO2 on optical properties of PVA. On the insertion of CeO2 nanoparticles (NPs) into the PVA matrix, the absorption edge was found to move to reduced photon energy sides. It was concluded that the CeO2 nanoparticles can be used to tune the refractive index (n) of the host polymer, and it reached up to 1.93 for 7 wt.% of CeO2 content. A detailed study of the bandgap (BG) was conducted using two approaches. The outcomes have confirmed the impact of the nanofiller on the BG reduction of the host polymer. The results of the optical BG study highlighted that it is crucial to address the ε” parameter during the BG analysis, and it is considered as a useful tool to specify the type of electronic transitions. Finally, the dispersion region of n is conferred in terms of the Wemple–DiDomenico single oscillator model.
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ATUCHIN, V. V., V. SH ALIEV, B. M. AYUPOV und I. V. KOROLKOV. „DECREASED REFRACTIVE INDEX OF NANOCRYSTALLINE ZIRCONIUM OXIDE THIN FILMS“. International Journal of Modern Physics B 26, Nr. 02 (20.01.2012): 1250012. http://dx.doi.org/10.1142/s0217979211102101.

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Amorphous zirconium oxide (a- ZrO 2) thin films were prepared onto fuzzed quartz substrates by ion beam sputtering deposition (IBSD) method in ( Ar + O 2) gas mixture. Optical parameters of the films were evaluated by laser ellipsometry (λ = 632.8 nm ) and optical transmission measurements. Structural parameters were studied by XRD measurements. Variation of refractive index and film thickness have been defined as a function of time of high-temperature annealing at T = 900° C . Formation of monoclinic zirconium oxide (m- ZrO 2) nanocrystals with diameter of ~60 nm embedded into a- ZrO 2 matrix has been found by XRD analysis after long-time annealing.
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Dhanya, I., und C. S. Menon. „Effect of Thickness on Structural and Optical Properties of Tetra-tert- butyl-2, 3-naphthalocyanine Thin Films“. E-Journal of Chemistry 8, Nr. 4 (2011): 1686–95. http://dx.doi.org/10.1155/2011/752982.

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Amorphous tetra-tert-butyl-2, 3-naphthalocyanine thin films have been deposited using physical vapor deposition technique under a varied thickness by adjusting the coating time. By analyzing the x-ray diffraction, the structure of as deposited films is found to be non-crystalline. Different optical properties of these thin films have been investigated by means of optical absorption and reflection spectra. Various optical constants like band gap energy, Egthe width of band tails of localized states into the gap, EUand steepness parameter, β gets calculated and the variation of different optical parameters like refractive index, extinction coefficient, dielectric constants, optical conductivity and surface and volume energy losses with photon energy are estimated.
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Michihata, Masaki, Deqing Kong, Kiyoshi Takamasu und Satoru Takahashi. „A Simulation Study of Plasmonic Substrate for In-Process Measurement of Refractive Index in Nano-Stereolithography“. International Journal of Automation Technology 11, Nr. 5 (30.08.2017): 772–80. http://dx.doi.org/10.20965/ijat.2017.p0772.

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Functional surfaces are in demand for recent value-added products. Stereolithography based on evanescent light has been proposed as a technique to fabricate surface nanostructures, but some fabrication error sources must be addressed. In-process measurement is an essential solution to improve the fabrication performance. For in-process measurement in stereolithography, the refractive index of resin is an inherent parameter for product and condition monitoring. This study proposes the in-process measurement of the refractive index of resin based on surface plasmon resonance (SPR). The optical phase response at SPR is highly sensitive to changes in the refractive index of resin but has a narrow sensing range. Therefore, we propose a substrate with a tunable sensing range using lanthanum-modified lead zirconate titanate (PLZT). The structural design was considered using numerical simulation. The SPR conditions were calculated with regard to thickness combinations of PLZT and metal (Ag) films. Depending on these combinations, a sensing range can be tuned on the order of 10-3to 10-4RIU with a sensitivity of 106rad/RIU. However, to realize these performances, the manufacturing accuracy of Ag thin films must be better than 0.1 nm.
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Dissertationen zum Thema "Structural parameter of refractive index"

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Maluš, Miroslav. „Komplexní model turbulence pro různé velikosti cel“. Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2021. http://www.nusl.cz/ntk/nusl-442416.

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This diploma thesis is about creating a program to model turbulent cells of different sizes on the chosen transmission path. The initial part of the work is devoted to the formation of atmospheric turbulence and the mathematical description of the extent of turbulence and its effect on optical waves. The methods of the turbulence generation and their physical description of formation are described below. The practical part is devoted to the created program in the MATLAB.
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Děcká, Klára. „Interferometrické měření fázových změn optického svazku v turbulenci“. Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2018. http://www.nusl.cz/ntk/nusl-377040.

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This master’s thesis deals with the impact of atmospheric turbulence on phase changes of a free space optical signal. This problematic is investigated by the interferometric method. A part of the thesis is focused on the phenomenon of atmospheric turbulence. Then the physical effect of interference is discussed and optical interferometers are described. The experimental part of the thesis is focused on measurement of phase shift of optical signal by interferometric method. The result of the thesis is to determine how phase shift of an optical beam depends on the strength of turbulence.
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Aubrecht, Ondřej. „Studium profilu strukturního parametru indexu lomu v atmosféře“. Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219818.

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This work is dedicated to structural parameter of the refractive index in the atmosphere Cn2 and his various models. For comparison the models are simulated only for one area and only for one day. The work represented the influence of atmospheric turbulence on the communication environment and on the individual models. In addition this work is for selected areas and for the input conditions created program for modeling of structural parameters and meteorological data in the atmosphere
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Rydström, Sara. „Regularization of Parameter Problems for Dynamic Beam Models“. Licentiate thesis, Växjö University, School of Mathematics and Systems Engineering, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-7367.

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The field of inverse problems is an area in applied mathematics that is of great importance in several scientific and industrial applications. Since an inverse problem is typically founded on non-linear and ill-posed models it is a very difficult problem to solve. To find a regularized solution it is crucial to have a priori information about the solution. Therefore, general theories are not sufficient considering new applications.

In this thesis we consider the inverse problem to determine the beam bending stiffness from measurements of the transverse dynamic displacement. Of special interest is to localize parts with reduced bending stiffness. Driven by requirements in the wood-industry it is not enough considering time-efficient algorithms, the models must also be adapted to manage extremely short calculation times.

For the developing of efficient methods inverse problems based on the fourth order Euler-Bernoulli beam equation and the second order string equation are studied. Important results are the transformation of a nonlinear regularization problem to a linear one and a convex procedure for finding parts with reduced bending stiffness.

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Kovaľová, Soňa. „Interferometrické měření optického signálu v turbulenci“. Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2019. http://www.nusl.cz/ntk/nusl-401960.

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The aim of this thesis is to quantify the impact of atmospheric turbulence on optical signal used in free space optic communication systems. The first part is associated with atmosphere as transmission medium. Following part deals with interferometry and components of interferometers. Various methods of analysis of trasmission environment for optical beam are introduced theoretically and experimentally. Mathematical apparatus based on Kolmogorov’s cascade theory, Rytov’s variance was used to find value of structural parameter of refraction as a main measure of turbulence intensity. Experimentally obtained data were subjected to statistical analysis. The visualization of interference pattern fluctuations under turbulent conditions is shown in the last section. Interferometric method was realized with Michelson interferometer.
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Yang, Zepeng. „Bird-inspired self-assembly of hollow nanoparticles“. University of Akron / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=akron1590589915703906.

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Bárta, Miroslav. „Vliv atmosférických turbulencí na optický svazek“. Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2009. http://www.nusl.cz/ntk/nusl-218156.

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The aim of this thesis is to study a free space optics and its application in communication technologies. It describes possible interrupting impacts on the beamed optical signal, which are signal noise, attenuation of the atmosphere and atmospheric turbulence. The basis of the thesis is to describe the impact of the atmospheric turbulences on the optical beam. Fluctuation of optical intensity in the optical beam has been measured and index of refraction structure parameter calculated. With its assistance, turbulence rate has been determined.
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Pepenene, Refuoe Donald. „Macroscopic and Microscopic surface features of Hydrogenated silicon thin films“. University of the Western Cape, 2018. http://hdl.handle.net/11394/6414.

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Magister Scientiae - MSc (Physics)
An increasing energy demand and growing environmental concerns regarding the use of fossil fuels in South Africa has led to the challenge to explore cheap, alternative sources of energy. The generation of electricity from Photovoltaic (PV) devices such as solar cells is currently seen as a viable alternative source of clean energy. As such, crystalline, amorphous and nanocrystalline silicon thin films are expected to play increasingly important roles as economically viable materials for PV development. Despite the growing interest shown in these materials, challenges such as the partial understanding of standardized measurement protocols, and the relationship between the structure and optoelectronic properties still need to be overcome.
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Onelli, Olimpia Domitilla. „Complex photonic structures in nature : from order to disorder“. Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/273768.

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Structural colours arise from the interaction of visible light with nano-structured materials. The occurrence of such structures in nature has been known for over a century, but it is only in the last few decades that the study of natural photonic structures has fully matured due to the advances in imagining techniques and computational modelling. Even though a plethora of different colour-producing architectures in a variety of species has been investigated, a few significant questions are still open: how do these structures develop in living organisms? Does disorder play a functional role in biological photonics? If so, is it possible to say that the optical response of natural disordered photonics has been optimised under evolutionary pressure? And, finally, can we exploit the well-adapted photonic design principles that we observe in Nature to fabricate functional materials with optimised scattering response? In my thesis I try to answer the questions above: I microscopically investigate $\textit{in vivo}$ the growth of a cuticular multilayer, one of the most common colour-producing strategies in nature, in the green beetles $\textit{Gastrophysa viridula}$ showing how the interplay between different materials varies during the various life stages of the beetles; I further investigate two types of disordered photonic structures and their biological role, the random array of spherical air inclusions in the eggshells of the honeyguide $\textit{Prodotiscus regulus}$, a species under unique evolutionary pressure to produce blue eggs, and the anisotropic chitinous network of fibres in the white beetle $\textit{Cyphochilus}$, the whitest low-refractive index material; finally, inspired by these natural designs, I fabricate and study light transport in biocompatible highly-scattering materials.
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Chan, Chun-Fan. „Side-polished and tilted fiber Bragg grating refractive index sensors for structural health monitoring applications“. 2007. http://hdl.handle.net/1993/29469.

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Bücher zum Thema "Structural parameter of refractive index"

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Ochs, G. R. A refractive-index structure parameter profiling system. Boulder, Colo: U.S. Dept. of Commerce, National Oceanic and Atmospheric Administration, Environmental Research Laboratories, Wave Propagation Laboratory, 1989.

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Ochs, G. R. A refractive-index structure parameter profiling system. Boulder, Colo: U.S. Dept. of Commerce, National Oceanic and Atmospheric Administration, Environmental Research Laboratories, Wave Propagation Laboratory, 1989.

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Ochs, G. R. A refractive-index structure parameter profiling system. Boulder, Colo: U.S. Dept. of Commerce, National Oceanic and Atmospheric Administration, Environmental Research Laboratories, Wave Propagation Laboratory, 1989.

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Ochs, G. R. A refractive-index structure parameter profiling system. Boulder, Colo: U.S. Dept. of Commerce, National Oceanic and Atmospheric Administration, Environmental Research Laboratories, Wave Propagation Laboratory, 1989.

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Ochs, G. R. A refractive-index structure parameter profiling system. Boulder, Colo: U.S. Dept. of Commerce, National Oceanic and Atmospheric Administration, Environmental Research Laboratories, Wave Propagation Laboratory, 1989.

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Ochs, G. R. A refractive-index structure parameter profiling system. Boulder, Colo: U.S. Dept. of Commerce, National Oceanic and Atmospheric Administration, Environmental Research Laboratories, Wave Propagation Laboratory, 1989.

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Analyzing the Effects of Meteorology on Radar Measured Index of Refraction Structure Parameter. Storming Media, 2001.

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Buchteile zum Thema "Structural parameter of refractive index"

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Weik, Martin H. „refractive-index profile parameter“. In Computer Science and Communications Dictionary, 1452. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/1-4020-0613-6_15877.

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Drobinski, Ph, A. Dabas, P. Delville, X. Favreau und P. H. Flamant. „Measurement of the Refractive Index Structure Parameter C n 2 in the Planetary Boundary Layer Using a Pulsed Coherent 10 μm Lidar in Direct Detection“. In Advances in Atmospheric Remote Sensing with Lidar, 251–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60612-0_62.

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Galiatsatos, Vassilios. „Refractive Index, Stress-Optical Coefficient, and Optical Configuration Parameter of Polymers“. In Physical Properties of Polymers Handbook, 823–53. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-69002-5_50.

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Freeman, Richard, James King und Gregory Lafyatis. „Models of Electromagnetic Response of Materials“. In Electromagnetic Radiation, 366–97. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198726500.003.0010.

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Physical models that relate the generalized complex permittivity and complex conductivity to the electronic structure of matter are introduced. The classical models of Drude and Lorentz give expressions for the complex index of refraction in a dielectric, while Drude models a metal as a plasma. Reflection and transmission properties of interfaces are expressed in terms of the complex index of refraction. Special consideration is given to the behavior of light propagation in the frequency vicinity of an atomic resonance of the material. Finally, measurement techniques are presented that are applicable to the determination of the parameters of a Lorentz/Drude representation of electromagnetic transmission in matter.
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„Design and Simulations of Negative Refractive Index Metamaterial (NIR) SRR and CSRR Structures“. In Modeling and Simulations for Metamaterials, 141–47. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-4180-6.ch006.

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This chapter evaluates the simulation studies performed on resonator-based structures to figure out the characteristics of metamaterial arrangement while incident the light horizontally. A double negative material is shown by the proposed structure as light hits along x-axis. Furthermore, it is noticed that different parameters of the structures effect the behavior of the left-handed metamaterial. Moreover, it is also noticed that changing the lattice constant ax and ay also affects the behavior of the left-handed metamaterial.
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Thomas, Michael E. „Spectroscopy of Matter“. In Optical Propagation in Linear Media. Oxford University Press, 2006. http://dx.doi.org/10.1093/oso/9780195091618.003.0007.

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It is critical to understand the nature of the propagation medium in terms of the available resonances which couple to the electromagnetic field. The detailed specification of the complex index of refraction as a function of frequency is the subject of spectroscopy. Since propagation media cover all phases of matter, the spectroscopy of gases, solids, and liquids is introduced in this chapter. Topics are not exhaustively covered, but rather with sufficient depth to support the practical applications that will come later. The chapter begins with a formal review of topics covered in stationary-state quantum mechanics necessary for the development of spectroscopy. The next section develops models to calculate spectral line positions, which are necessary to characterize a spectral line. The full development of spectral line parameters is not only the goal of this chapter but the next two as well. The remaining sections address the essential elements of the spectroscopy of gases, solids and liquids. Both classical and quantum models are used. Time-independent quantum mechanics allows the description of the quantized energy level structure of matter. This is the central topic of this chapter. Time-dependent quantum mechanics is necessary for the development of a theory covering transitions between stationary-state energy levels and is the topic of Chapter 5. The classical concept of light is that of an oscillating continuous wave field, as presented in the first two chapters. This is consistent with the classical electrodynamics based on Maxwell’s equations. However, the work by Planck on blackbody radiation and Einstein on the photoelectric effect showed that optical fields also have a quantized or particle-like nature. Planck, in 1900, suggested that the energy of light, E, be quantized according to . . . E = h f [J] (3.1) . . . where f is frequency (sec−1) and h is Planck’s constant (h = 6.6260755(40) × 10−34 J-sec). This allowed a theoretical description of blackbody radiation for the first time. However, it was Einstein, who, a few years later, made Eq. 3.1 more credible by applying it to explain the photoelectric effect.
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Umamaheswari, A., A. Puratchikody und Sakthivel Balasubramaniyan. „Target Identification of HDAC8 Isoform for the Treatment of Cancer“. In Advances in Medical Technologies and Clinical Practice, 140–72. IGI Global, 2019. http://dx.doi.org/10.4018/978-1-5225-7326-5.ch007.

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Target identification has been considered as a chief parameter in drug discovery as it fully characterizes on-target and off-target effects of drug binding. Cell signaling receptors, structural proteins, and post-translational modifications of histones by histone deacetylases are the most widespread targets that are progressively being explored. The FDA approved histone deacetylases inhibitors and the majority of HDACi in and out of clinical trials based on the activities of 11 isoforms of the enzyme in non-selective influence approach. Unfortunately, reported HDACi does not possess a high degree of structural specificity and ultimately lessens the therapeutic index with many dose limiting toxicities. This chapter illustrates how different approaches are incorporated into the novel inhibitors discovery that are truly isoform-selective and which are specifically involved in targeting only a particular isozyme. Further, it highlights the aspects relating to provide a wider therapeutic index with an improved toxicity profile of lead like epigenetic modulators.
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Konferenzberichte zum Thema "Structural parameter of refractive index"

1

Henriksson, Markus, und Robin Forsling. „Temporally resolved refractive index structure parameter measurement“. In Optics in Atmospheric Propagation and Adaptive Systems, herausgegeben von Karin U. Stein und Szymon Gladysz. SPIE, 2017. http://dx.doi.org/10.1117/12.2278315.

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Yazar, Ibrahim, Yusuf E. Yenice und Filiz Sari. „Probability distribution of refractive index structure parameter“. In 2017 25th Signal Processing and Communications Applications Conference (SIU). IEEE, 2017. http://dx.doi.org/10.1109/siu.2017.7960584.

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Xuan, Yimin, Jinguo Huang und Qiang Li. „Tunable Negative Refractive Index Metamaterials Based on Thermochromic Oxides“. In ASME 2012 Third International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/mnhmt2012-75033.

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A tunable metamaterial is proposed by combining a thermochromic oxide with a fishnet structure. The reflection and transmission coefficients are calculated by finite-difference time-domain (FDTD) method. Then the effective electromagnetic parameters of the metamaterial are retrieved on the basis of these data. The results reveal that an effective negative refractive index is obtained by this proposed structure. Furthermore, the wavelength region with negative refractive index can be self-regulated by simply tuning the temperature, which is of importance to extend the applications of negative refractive index materials. The effects of structural sizes on the negative refractive index are discussed in detail. The size-dependence indicates that wavelength region with negative refractive index can be designed to locate at the desired position by dexterously tailoring the structural parameters.
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4

Lamprecht, Christopher, Pasha Bekhrad, Hristo Ivanov und Erich Leitgeb. „Modelling the Refractive Index Structure Parameter: A ResNet Approach“. In 2020 International Conference on Broadband Communications for Next Generation Networks and Multimedia Applications (CoBCom). IEEE, 2020. http://dx.doi.org/10.1109/cobcom49975.2020.9174186.

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Rudiger, Joshua J., John S. deGrassie, Stephen Hammel, Kevin Book und Brook Baker. „A machine learning approach for forecasting the refractive index structure parameter“. In Laser Communication and Propagation through the Atmosphere and Oceans VII, herausgegeben von Alexander M. van Eijk, Stephen Hammel und Jeremy P. Bos. SPIE, 2018. http://dx.doi.org/10.1117/12.2323835.

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Eaton, Frank, Bruce Masson, Ila Hahn, Sean Borror, Brad Rennich, Frank Eaton, Bruce Masson, Ila Hahn, Sean Borror und Brad Rennich. „Comparison of aircraft and radar observations of the refractive index structure parameter“. In 28th Plasmadynamics and Lasers Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1997. http://dx.doi.org/10.2514/6.1997-2354.

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7

Ochs, Gerard R. „Measurement Of The Refractive-Index Structure Parameter By Incoherent Aperture Scintillation Techniques“. In SPIE 1989 Technical Symposium on Aerospace Sensing, herausgegeben von Norman S. Kopeika und Walter B. Miller. SPIE, 1989. http://dx.doi.org/10.1117/12.960863.

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Hannah, Emily D., William C. Swann, Jennifer L. Ellis, Martha I. Bodine, Carter Mak, Nathan Kuczun, Nathan R. Newbury, Laura C. Sinclair, Andreas Muschinski und Gregory B. Rieker. „Retrieval of the Refractive Index Structure Parameter from Frequency Comb Timing Jitter Data“. In Propagation Through and Characterization of Atmospheric and Oceanic Phenomena. Washington, D.C.: OSA, 2020. http://dx.doi.org/10.1364/pcaop.2020.ptu4f.5.

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Zhao, Junwei, Xiwen Qiang, Zhigang Zhang, Shuanglian Feng und Yuehong Hu. „A measurement system of atmospheric refractive index structure parameter based on solar power device“. In 6th International Symposium on Advanced Optical Manufacturing and Testing Technologies (AOMATT 2012), herausgegeben von Yadong Jiang, Junsheng Yu und Zhifeng Wang. SPIE, 2012. http://dx.doi.org/10.1117/12.975652.

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Leclerc, Troy T., Ronald L. Phillips, Larry C. Andrews, David T. Wayne, Paul Sauer und Robert Crabbs. „Prediction of the ground-level refractive index structure parameter from the measurement of atmospheric conditions“. In SPIE Defense, Security, and Sensing, herausgegeben von Linda M. Wasiczko Thomas und Earl J. Spillar. SPIE, 2010. http://dx.doi.org/10.1117/12.852426.

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Berichte der Organisationen zum Thema "Structural parameter of refractive index"

1

Tunick, Arnold D. The Refractive Index Structure Parameter/Atmospheric Optical Turbulence Model: CN2. Fort Belvoir, VA: Defense Technical Information Center, April 1998. http://dx.doi.org/10.21236/ada341685.

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Chang, Mark P., Carlos O. Font, G. C. Gilbreath und Eun Oh. Humidity's Influence on Visible Region Refractive Index Structure Parameter Cn2. Fort Belvoir, VA: Defense Technical Information Center, Mai 2007. http://dx.doi.org/10.21236/ada474836.

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