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Thematische Bibliographien / Steroidal constituents

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Zeitschriftenartikel
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Auswahl der wissenschaftlichen Literatur zum Thema „Steroidal constituents“

Autor: Grafiati

Veröffentlicht am 18. Mai 2024

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Zeitschriftenartikel zum Thema "Steroidal constituents"

1

Gan, Kim-Hong, Shieh-Hsieh Kuo und Chun-Nan Lin. „Steroidal Constituents ofGanodermaapplanatumandGanodermaneo-japonicum“. Journal of Natural Products 61, Nr. 11 (November 1998): 1421–22. http://dx.doi.org/10.1021/np980184j.

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Siddiqui, Bina Shaheen, Shahid Bader Usmani, Sabira Begum und Salimuzzaman Siddiqui. „Steroidal Constituents of Holarrhena pubescens“. Journal of Natural Products 57, Nr. 1 (Januar 1994): 27–31. http://dx.doi.org/10.1021/np50103a004.

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3

Hu, Ying-Jie, Xiao-Ling Shen, Qan-Zhang Mu, Yang Lu und Qi-Tai Zheng. „Steroidal constituents from Amalocalyx yunnanesis“. Phytochemistry 31, Nr. 6 (Juni 1992): 2099–102. http://dx.doi.org/10.1016/0031-9422(92)80370-t.

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4

Gaspar, Elvira M. M., und Higuinaldo J. C. das Neves. „Steroidal constituents from mature wheat straw“. Phytochemistry 34, Nr. 2 (September 1993): 523–27. http://dx.doi.org/10.1016/0031-9422(93)80039-u.

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5

Ahmad, Ijaz, Abdul Malik, Nighat Afza, Itrat Anis, Itrat Fatima, Sarfraz Ahmad Nawaz, Rasool Bukhsh Tareen und M. Iqbal Choudhary. „Enzymes Inhibitory Constituents From Buddleja Crispa“. Zeitschrift für Naturforschung B 60, Nr. 3 (01.03.2005): 341–46. http://dx.doi.org/10.1515/znb-2005-0319.

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Steroidal galactoside 1 and aryl esters 2 and 3 have been isolated from Buddleja crispa, along with ginipin 4, gardiol 5, 1-heptacosanol 6, and methyl benzoate 7, isolated for the first time from this species. The structures of all of the compounds were determined by spectroscopic techniques and chemical studies. The steroidal galactoside 1 is an inhibitor of lipoxygenase. Compounds 1- 3 displayed inhibitory activity against butyrylcholinesterse, while compounds 2 and 3 further showed inhibition against acetylcholinesterase

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Shah, Sherine Majeed, und Thukaa Z. Abdul-Jalil. „Qualitative and Quantitative Estimation or Chemical Constituents from Leaves and Roots of Iraqi Agave Attenuata by GC-MS and RP-HPLC(Conference Paper) #“. Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 31, Suppl. (16.02.2023): 75–85. http://dx.doi.org/10.31351/vol31isssuppl.pp75-85.

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This research concentrate on cultivated Iraqi Agave attenuata dried leaves and roots, because of little studies on this plant especially on the root that lead to the eager of study and comparison of phytochemical constituents between leaves and root. Extraction of bioactive constituents was carried out using several solvents with increasing polarity (n-hexane, ethyl acetate and methanol) by soxhlet apparatus. Steroidal saponins in Agave genus is well documented in many species, lightening the minds in this research on extraction method which is specific for steroidal saponins. Phytochemical screening was done by GC/MS for n-hexane fraction, qualitative and quantitative estimation of several bioactive constituents (caffeic acid, p-coumaric acid, and quercetin) for ethyl acetate and methanol fractions while for steroidal saponins (sarsasapogenin, hecogenin and tigogenin) in both leaves and root by using reverse phase-high performance liquid chromatography (RP-HPLC). Among those identified phytochemical constituents, several constituents have not been detected in Agave attenuata leaves and roots before. This study is the first to describe the results in which the highest concentration of caffeic acid was found in leaves ethyl acetate fraction, p-coumaric acid and quercetin in root ethyl acetate fractions. While for steroidal saponins, the hecogenin, tigogenin and sarsasapogenin highest concentrations were found in leaves.

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Ivanchina, Natalia V., Alla A. Kicha, Anatoly I. Kalinovsky, Pavel S. Dmitrenok, Valentin A. Stonik, Ricardo Riguera und Carlos Jiménez. „Hemolytic Polar Steroidal Constituents of the StarfishAphelasteriasjaponica“. Journal of Natural Products 63, Nr. 8 (August 2000): 1178–81. http://dx.doi.org/10.1021/np000030f.

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8

Zaki, A., J. Schmidt, F. Hammouda und G. Adam. „Steroidal Constituents from Pollen Grains ofPhoenix dactylifera“. Planta Medica 59, S 1 (Dezember 1993): A613—A614. http://dx.doi.org/10.1055/s-2006-959837.

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9

Mimaki, Yoshihiro, und Yutaka Sashida. „Steroidal and phenolic constituents of Lilium speciosum“. Phytochemistry 30, Nr. 3 (Januar 1991): 937–40. http://dx.doi.org/10.1016/0031-9422(91)85283-6.

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YANG, Q., Y. ZHANG, H. LI und C. YANG. „Polyhydroxylated steroidal constituents from the fresh rhizomes of“. Steroids 70, Nr. 10 (September 2005): 732–37. http://dx.doi.org/10.1016/j.steroids.2005.04.003.

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Dissertationen zum Thema "Steroidal constituents"

1

Betteridge, Jordan. „Isolation and structure elucidation of the antibacterial constituents of Sphaeranthus indicus, the steroidal alkaloids of Buxus hyrcana, and biotransformation studies on terpenoids“. 2008. http://hdl.handle.net/1993/21072.

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2

Lin, Chi-Wen, und 林啟文. „1. Steroids and Triterpenoids from the Fruiting Bodies of Ganoderma mastoporum Collected in Vietnam2. Chemical Constituents from the Leaves of Zanthoxylum scabrum Collected in Vietnam“. Thesis, 2013. http://ndltd.ncl.edu.tw/handle/dg7h88.

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碩士
國立虎尾科技大學
生物科技研究所
101
The methanol extracts from the fruiting bodies of Ganoderma mastoporum collected from Vietnam was purified to afford 8 compounds. To evaluate their in vitro antioxidant potentials, the purified compounds were examined for the scavenging activities of DPPH free radicals and capability of chelating ferrous ions. These isolates would be subjected into the pharmacology activity examinations to explore new natural anti-inflammatory drugs and may be potential sources for the development of healthy foods. Zanthoxylum scabrum is a Rutaceae plants distributed in North Vietnam, Northeast Thailand and Southern China. In our studies the methanol extracts of the leaves of Z. scabrum from Vietnam screened for pharmacology activity has been found in vitro anti-inflammatory activity. The chloroform layer and precipitation layer of methanol extracts of the leaves of Z. scabrum inhibited fMLP/CB induced superoxide anion generation in a concentration-dependent manner with IC50 values of 2.79±0.34 and 2.20±0.08 μg/mL; inhibited fMLP/CB induced elastase release in a concentration-dependent manner with IC50 values of 1.97±0.27 and 2.63±0.18 μg/mL, respectively. Therefore, the present research is aimed to the bioactivity and the chloroform layer of methanol extracts of the leaves of Z. scabrum were fractionated and further purified to afford 11 compounds. These isolates would be subjected into the pharmacology activity examinations to explore new natural anti-inflammatory drugs.

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Buchteile zum Thema "Steroidal constituents"

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Pengelly, Andrew. „Triterpenoids and saponins.“ In The constituents of medicinal plants, 95–111. 3. Aufl. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789243079.0006.

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Abstract This chapter focuses on the various classes of triterpenoids (free triterpenes, triterpenoid saponins, steroidal saponins, cardiac glycosides, phytosterols, phytoecdysteroids, curcurbitacins and quassinoids), which occur in the free state within plants or as aglycones of glycosides. Information on the chemical structures and pharmacological actions of these triterpenoids and saponins are also presented.

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Kumar Dixit, Amit, Avijit Banerji, Julie Banerji, Deepti Dixit, Parvathy G. Nair und Damodar Gupta. „Bioactive Constituents and Anti-diabetic Activity of the Indian Medicinal Plant Hemidesmus indicus R. Br.: An Overview“. In Therapeutic Implications of Natural Bioactive Compounds, 176–204. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815080025122030012.

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Hemidesmus indicus R. Br. is a laticiferous, slender, and twining shrub, which is found over almost every part of India. Its roots (Anantmul - Sanskrit meaning: endless root) are particularly used extensively as a single drug and in formulations with other plants to treat several ailments. In view of the wide range of medicinal properties claimed in traditional medicine, significant efforts have been made to determine the efficacy of Hemidesmus indicus through pharmacological experiments in vitro and in vivo models. These include analgesic, anti-inflammatory, antipyretic, antioxidant, antiarthritic, hepatoprotective, antiepileptic, anticonvulsant, antiulcer, antivenom, antiacne, and antipsychotic activities. Recent studies have also established anti.diabetic, anti-carcinogenic, anti-venom, and wound healing activities. Extensive phytochemical investigations have been carried out by several research groups. The present review provides an overview of the bioactive compounds of this Indian medicinal plant. Several classes of compounds, viz. triterpenoids, steroids, steroid glycosides, coumarin-lignoids, flavonoids in addition to many simpler compounds, have been isolated and characterised from different parts of H. indicus. These are listed, along with brief write-ups on isolation procedures, spectroscopical and chemical characterization, and their biological properties. Particular emphasis is given to the anti-diabetic properties associated with it, indicus root extracts, and the factors contributing to these properties

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Takami, Shigeru, und Sawa Horie. „Functional Roles of Estradiol in the Olfactory and Vomeronasal Mucosae of Mammals: A Working Hypothesis“. In Estrogens - Recent Advances [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106662.

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It has been known that androgens and estrogens, which are referred to as sex steroids, make many effects on two major nasal chemosensory mucosae such as olfactory mucosa and vomeronasal organ. Our studies conducted in rodents have demonstrated that two of the constituent cells in the olfactory mucosa, sustentacular cells and acinar cells in the associated glands of the olfactory mucosa, Bowman’s glands, express four different enzymes involved in the biosynthesis of estradiol-17β (E2). Furthermore, our ongoing study has shown that olfactory sensory cells contain immunoreactivity for an estrogen receptor (beta-type). In case of vomeronasal organ, vomeronasal sensory cells express two enzymes that catalyze conversion of E2 and estrone, and that of testosterone and androstenedione. In addition, vomeronasal sensory cells contain an estrogen receptor (alpha-type). These results strongly suggest that de novo synthesis of E2 and metabolism of E2 take place in the olfactory mucosa and vomeronasal organ, respectively. With special emphasis of subcellular characteristics of steroid-producing cells, such as presence of large amount of smooth endoplasmic reticulum and vesicular mitochondria, we will introduce our findings and present working hypotheses for E2 functions in the olfactory mucosa and vomeronasal organ.

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Romeo, Stefano. „Genetic defects in sterol synthesis, absorption, and degradation into bile acids“. In Oxford Textbook of Endocrinology and Diabetes, 1673–76. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.1246.

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Cholesterol is the most abundant steroid in animals. Not only is it a vital constituent of cell membranes, where it establishes proper membrane permeability and fluidity, but it is also the immediate metabolic precursor of all known steroid hormones and bile acids. Synthesized de novo in cells or absorbed from the diet, cholesterol circulates in the body in association with lipoproteins and is ultimately degraded into bile acids by the liver. Every perturbation of the numerous enzymes involved in cholesterol metabolism leads to impairment in the development and function of the gastrointestinal, cardiovascular, skeletal, and nervous systems.

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Okuyama, Tadashi, und Howard Maskill. „Chemistry of Biomolecules“. In Organic Chemistry. Oxford University Press, 2013. http://dx.doi.org/10.1093/hesc/9780199693276.003.0024.

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This chapter addresses some of the major constituents of our body: carbohydrates, nucleic acids, proteins, and lipids, and related compounds. It emphasizes that although structures of many biomolecules may be complicated, their chemistry is not especially difficult. The chapter notes that their reactions are governed by the principles of the chemistry of simple organic compounds. The chapter also introduces the kinds of compounds which play major roles in living systems, and identifies the molecular features which allow them to function in their biological roles. Finally, the chapter looks at fats and oils, and phospholipids. It then considers the nature of terpenes, steroids, and eicosanoids.

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Gutteridge, John M. C., und Barry Halliwell. „Appendix to Chapter 1 Cholesterol, saturated, and unsaturated fats. What do they do in the body?“ In Antioxidants in Nutrition, Health, and Disease, 17–23. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780198549024.003.0004.

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Abstract Membranes encircle all cells and control the exchange of material between the cell and its surroundings. Inside cells, membranes separate the different cell compartments (organelles, such as nucleus and mitochondria) from the fluid cell matrix (the cytosol). The main constituents of membranes are lipid and protein, the amount of protein increasing with the number of functions the membrane performs. ‘ Lipid’ is a general term used to describe any biological compound that is soluble in organic solvents such as chloroform and ether. The term includes both molecules that contain fatty acids, examples being triglycerides and phospholipids, and molecules containing hydrocarbon ring structures, examples being cholesterol, steroid hormones, and some of the fat-soluble vitamins.

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Kumar Sahu, Pratap, und Prashant Tiwari. „Impact of Shodhana on Semecarpus anacardium Nuts“. In Alternative Medicine - Update. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.94189.

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Semecarpus anacardium is classified in Ayurveda under the category of toxic plants. However, this toxic plant is reported to possess anti-inflammatory activity, anti-arthritic effect, antioxidant activity, antimicrobial activity, anti- carcinogenic activity, hypoglycemic activity, cardioprotective, hepatoprotective, neuroprotective, and hypolipidemic activity etc. All these activities are attributed to its various constituents like phenolic compounds, flavonoids, carbohydrates, alkaloids, steroids, etc. In Ayurveda, a series of pharmaceutical procedures which converts a poisonous drug into a safe and therapeutically effective medicine is termed as Shodhana. Shodhana improves the yield, decreases the phenolic and flavonoid content; and converts toxic urushiol into nontoxic anacardol derivative thereby reducing toxicity of nuts of Semecarpus anacardium. There are reports of alteration in pharmacology and phytochemistry of nuts of Semecarpus anacardium due to Shodhana.

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„CHARACTERIZATION OF DIFFERENT FORMS OF THE ANDROGEN RECEPTOR AND THEIR INTERACTION WITH CONSTITUENTS OF CELL NUCLEI“. In Molecular Mechanism of Steroid Hormone Action, 563–86. De Gruyter, 1985. http://dx.doi.org/10.1515/9783110885026.563.

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Behre, Hermann M., und Eberhard Nieschlag. „Endocrine evaluation“. In Oxford Textbook of Endocrinology and Diabetes, 1363–68. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.9037.

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The main constituent of endocrine laboratory diagnosis of testicular dysfunction is the determination of the gonadotropins, luteinizing hormone and follicle-stimulating hormone (FSH) secreted from the pituitary gland, of testosterone secreted from the Leydig cells, and of inhibin-B secreted from the Sertoli cells. Where hypothalamic or pituitary disorders are suspected as causes of testicular dysfunction, a gonadotropin-releasing hormone (GnRH) stimulation test can be performed for further differentiation. A human chorionic gonadotropin (hCG) stimulation test is done for evaluation of the endocrine reserve capacity of the testis. Additional hormone measurements are performed for special diagnostic questions, e.g. of oestradiol in cases of gynaecomastia, or hCG and oestradiol upon suspicion of a testicular tumour. Various steroid hormones, including dihydrotestosterone, androgen receptors, or androgen metabolizing enzymes (e.g. 5α‎-reductase) in the target organs are analysed in patients with disturbances of sexual differentiation.

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Zeeshan Bhatti, Muhammad, und Aman Karim. „Plant Natural Products: A Promising Source of Hyaluronidase Enzyme Inhibitors“. In Extracellular Matrix - Developments and Therapeutics [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98814.

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Hyaluronidase enzyme degrades hyaluronan, the primary component of the extracellular matrix found in connective tissues animals and on the surface of certain pathogenic bacteria. The degradation of hyaluronan is linked to a wide range of physiological and pathological process. Inhibiting the hyaluronidase enzyme is thus significant as an approach to treat a variety of diseases and health conditions such as anti-fertility, anti-tumor, antimicrobial, and anti-venom/toxin agents. HAase inhibitors of different chemical types have been identified include both synthetic compounds and constituents obtained from naturally sources. Plant natural products as HAase inhibitors are unique due to their structural features and diversity. Medicinal plants have historically been used as contraceptives, antidote for snakebites and to promote wound healing. In recent years, small molecules, particularly plant natural products (alkaloids, flavonoids, polyphenol and flavonoids, triterpenes and steroids) possessing potent HAase have been discovered. A number of plant species from various families, which have folk medicinal claims for these ailments (related to hyaluronan disturbances) were scientifically proven for their potential to block HAase enzymes.

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