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Thematische Bibliographien / Staphylococcic

Auswahl der wissenschaftlichen Literatur zum Thema „Staphylococcic“

Autor: Grafiati

Veröffentlicht am 4. Juni 2021

Zuletzt aktualisiert am 29. Januar 2023

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Dissertationen
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Zeitschriftenartikel zum Thema "Staphylococcic":

1

Nikolaeva, I. V., V. A. Anokhin, L. M. Malysheva, A. M. Nikolaev und B. N. Vasenin. „Clinic of staphylococcal intestinal dysbacteriosis in children“. Kazan medical journal 81, Nr. 5 (02.02.2022): 396–99. http://dx.doi.org/10.17816/kazmj96337.

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The variants of the course of staphylococcic intestine dysbacteriosis in 264 children aged one month to 7 years are studied. In babies with decreased colonizational resistance the pathogenic staphylococcus contamination in 79 92,3% of the cases is accompanied by the clinical infection symptomatology of gastroenteric tract and various extraenteric manifestations. In children over one year the given microbiocenosis disorder variant in 45 59,5% of the cases takes the course of asymptomatic bacteria carrier Saureus in intestine. Subcompensated forms are characterized by moderately pronounced clinical symptomatology. The infants infected by pathogenic staphylococcus in the first months of life are subjected to the development of allergodermatoses, staphylococcic infection, hypotrophy and anemia.

2

Lithander, Arne. „Method of Producing Staphylococcic Toxin“. Acta Pathologica Microbiologica Scandinavica 21, Nr. 5 (14.08.2009): 764–67. http://dx.doi.org/10.1111/j.1699-0463.1944.tb04976.x.

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3

Lithander, Arne. „ANTITOXIC IMMUNITY AS PROTECTION AGAINST STAPHYLOCOCCIC INFECTION“. Acta Pathologica Microbiologica Scandinavica 53, Nr. 4 (18.08.2009): 356–62. http://dx.doi.org/10.1111/j.1699-0463.1961.tb00419.x.

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4

Lagier, R. „Coexistence of staphylococcic spondylitis and spinal hyperostosis“. RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 147, Nr. 10 (Oktober 1987): 452–53. http://dx.doi.org/10.1055/s-2008-1048676.

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5

Montero, Luis Caminal, Rui M. Cabral Susano, Alicia González Marroquin und Luis Ovidio González. „Aortic Root Staphylococcic Endarteritis With Aortopulmonary Fistula“. Chest 105, Nr. 5 (Mai 1994): 1631–32. http://dx.doi.org/10.1378/chest.105.5.1631.

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6

Lithander, Arne. „Method of Producing Purified and Concentrated Staphylococcic Toxoid“. Acta Pathologica Microbiologica Scandinavica 21, Nr. 5 (14.08.2009): 759–63. http://dx.doi.org/10.1111/j.1699-0463.1944.tb04975.x.

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7

Falkenberg, Trygve. „MACROPHAGES IN THE PERIPHERAL BLOOD IN STAPHYLOCOCCIC SEPSIS“. Acta Pathologica Microbiologica Scandinavica 24, Nr. 1 (18.08.2009): 1–10. http://dx.doi.org/10.1111/j.1699-0463.1947.tb00572.x.

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8

Cunha und R. A. O. Calsolari. „Toxigenicity in Staphylococcus aureus and Coagulase-Negative Staphylococci: Epidemiological and Molecular Aspects“. Microbiology Insights 1 (Januar 2008): MBI.S796. http://dx.doi.org/10.4137/mbi.s796.

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Representatives of the Staphylococcus genus are the most common pathogens found in hospital environments, and they are etiological agents for a large variety of infections. Various virulence factors are responsible for the symptoms and severity of infections caused by Staphylococcus aureus. Among them are staphylococcal enterotoxins (SEs), which cause staphylococcal food poisoning, and toxic shock syndrome toxin-1 (TSST-1). Some reports indicate that TSST-1 and staphylococcal enterotoxins are also produced by coagulase-negative staphylococci (CNS). The present review aimed to discuss general aspects of staphylococcal toxins as well as the epidemiology, genetics and detection of toxins in Staphylococcus aureus and coagulase-negative staphylococci, since these microorganisms are becoming more and more frequent in nosocomial infections.

9

Eichenwald, Heinz F., Henry R. Shinefield, Marvin Boris und John C. Ribble. „“BACTERIAL INTERFERENCE” AND STAPHYLOCOCCIC COLONIZATION IN INFANTS AND ADULTS*“. Annals of the New York Academy of Sciences 128, Nr. 1 (16.12.2006): 365–80. http://dx.doi.org/10.1111/j.1749-6632.1965.tb11649.x.

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10

Michael, Charalambia K., Daphne T. Lianou, Natalia G. C. Vasileiou, Katerina Tsilipounidaki, Angeliki I. Katsafadou, Antonis P. Politis, Nikos G. Kordalis et al. „Association of Staphylococcal Populations on Teatcups of Milking Parlours with Vaccination against Staphylococcal Mastitis in Sheep and Goat Farms“. Pathogens 10, Nr. 4 (24.03.2021): 385. http://dx.doi.org/10.3390/pathogens10040385.

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There is a paucity of information regarding staphylococcal populations on teatcups of milking parlours in sheep and goat farms. The objectives were to describe the populations of staphylococci on teatcups in milking parlours in sheep or goat farms in two field investigations throughout Greece and to potentially associate the findings with the use of anti-staphylococcal mastitis vaccinations in the farms visited during the two investigations. In a cross-sectional (255 sheep and 66 goat farms across Greece) and a longitudinal (12 sheep farms, four samplings, throughout lactation) study, swab samples were collected from 1418 teatcups (upper and lower part) for staphylococcal recovery, identification and assessment of biofilm-formation. A total of 328 contaminated teatcups (23.1%) were found in 105 sheep (41.2%) and 35 goat (53.0%) farms. Staphylococci were more frequently recovered from the upper than the lower part of teatcups: 269 versus 139 teatcups, respectively. After identification, 253 staphylococcal isolates were found: Staphylococcus aureus, Staphylococcus equorum, Staphylococcus lentus, and Staphylococcus capitis predominated. Of these isolates, 87.4% were biofilm-forming. The proportion of contaminated teatcups was smaller in farms where vaccination against anti-staphylococcal mastitis in general or vaccination specifically against mastitis caused specifically by biofilm-forming staphylococcal strains was applied, 19.7% or 10.9%, respectively, versus 25.5% in farms without vaccination. In the longitudinal study, contaminated teatcups were identified in 28 (58.3%) sampling occasions, with staphylococci being recovered more frequently from their upper part. The same species as in the cross-sectional study predominated. Of these isolates, 61.9% were biofilm-forming. In farms where vaccination against mastitis caused specifically by biofilm-forming staphylococcal strains was applied, the proportion of contaminated teatcups was smaller: 20.4% versus 48.3% in farms without vaccination. There were no differences in proportions of contaminated teatcups between sampling occasions. In conclusion, the great majority of staphylococci recovered from teatcups of milking parlours in sheep and goat farms included biofilm-forming isolates. Reduced staphylococcal isolation was noted in farms where anti-staphylococcal vaccination was performed; this was possibly the effect of reduced excretion of staphylococci in the milk of vaccinated animals.

Mehr Quellen

Dissertationen zum Thema "Staphylococcic":

1

Bjertsjö, Rennermalm Anna. „Staphylococcal cell wall associated proteins : characteristics and host interactions /“. Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-542-9/.

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2

Lamers, Ryan Paul. „Evolutionary relationships among staphylococci and the prevention of Staphylococcus aureus nasal colonization“. Doctoral diss., University of Central Florida, 2011. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4782.

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Staphylococcus is a significant cause of human infection and mortality, worldwide. Currently, there are greater than 60 taxa within Staphylococcus, and nearly all are pathogenic. The collective potential for virulence among species of Staphylococcus heightens the overall clinical significance of this genus and argues for a thorough understanding of the evolutionary relationships among species. Within Staphylococcus, aureus is the most common cause of human infection, where nasal carriage of this bacterium is a known risk factor for autoinfection. The predisposition to infection by nasal carriers of S. aureus, and the ease with which strains are transferred between individuals, suggests that nasal carriage is a major vector for the transmission of virulent strains throughout the community. This hypothesis, however, has not been assessed in any great detail to identify the genetic relationships between clinical isolates of S. aureus and those strains being carried asymptomatically throughout the community. Also lacking within this field is a unified and robust estimate of phylogeny among species of Staphylococcus. Here, we report on a highly unified species phylogeny for Staphylococcus that has been derived using multilocus nucleotide data under multiple Bayesian and maximum likelihood approaches. Our findings are in general agreement with previous reports of the staphylococcal phylogeny, although we identify multiple previously unreported relationships. Regardless of methodology, strong nodal support and high topological agreement was observed with only minor variations in results between methods. Based on our phylogenetic estimates, we propose that Staphylococcus species can be evolutionarily clustered into 15 groups, and six species groups. In addition, our more defined phylogenetic analyses of S. aureus revealed strong genetic associations between both nasal carriage strains and clinical isolates. Genetic analyses of hypervariable regions from virulence genes revealed that not only do clinically relevant strains belong to identical genetic lineages as the nasal carriage isolates, but they also exhibited 100% sequence similarity within these regions. Our findings indicate that strains of S. aureus being carried asymptomatically throughout the community via nasal colonization are genetically related to those responsible for high levels of infection and mortality. Due to nasal carriage of S. aureus being a risk factor for autoinfection, standardized preoperative decolonization has become a major consideration for the prevention of nosocomial infection. Toward this end, we have identified the macrocyclic ?-defensin analogue RC-101 as a promising anti-S. aureus agent for nasal decolonization. RC-101 exhibited bactericidal effects against S. aureus in both epithelium-free systems, and ex vivo models containing human airway epithelia. Importantly, RC-101 exhibited potent anti-S. aureus activities against all strains tested, including USA300. Moreover, RC-101 significantly reduced the adherence, survival, and proliferation of S. aureus on human airway epithelia without any noted cellular toxicity or the induction of a proinflammatory response. Collectively, our findings identify RC-101 as a potential preventative of S. aureus nasal colonization.
ID: 030646199; System requirements: World Wide Web browser and PDF reader.; Mode of access: World Wide Web.; Thesis (Ph.D.)--University of Central Florida, 2011.; Includes bibliographical references (p. 140-159).
Ph.D.
Doctorate
Molecular Biology and Microbiology
Medicine
Biomedical Sciences

3

Raupelytė, Eglė. „Koaguliazei teigiamų stafilokokų išskyrimas iš gyvūnų augintinių“. Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140305_133815-68093.

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Darbo tikslas: nustatyti koaguliazei teigiamų stafilokokų paplitimą tarp gyvūnų augintinių. Darbo uždaviniai: 1. išskirti koaguliazei teigiamus stafilokokus iš gyvūnų augintinių nosies ertmės; 2. išskirti koaguliazei teigiamus stafilokokus iš gyvūnų augintinių tiesiosios žarnos; 3. identifikuoti išskirtas stafilokokų padermes; 4. įvertinti įvairių veiksnių įtaką stafilokokų paplitimui; 5. nustatyti išskirtų stafilokokų atsparumą antimikrobinėms medžiagoms. Darbo apimtis – 50 puslapių. Šiame darbe yra 6 lentelės bei 14 paveikslų. Magistro darbą sudaro 4 dalys. Pirmojoje dalyje apžvelgiami literatūros šaltiniai susiję su analizuojama tema, išskiriant koaguliazei teigiamų stafilokokų virulentiškumo veiksnius, atsparumą antimikrobinėms medžiagoms, sukeliamas ligas ir šių ligų gydymą. Aptariamas Staphylococcus aureus bei Staphylococcus pseudintermedius paplitimas ir paplitimą įtakojantys veiksniai. Antrojoje dalyje nurodyti tyrimo metodai, kuriais remiantis gauti duomenys tyrimų analizei. Trečiojoje dalyje analizuojami gauti tyrimo rezultatai pagal iškeltus uždavinius. Rezultatai pateikiami atsižvelgiant į statistinių duomenų patikimumą. Ketvirtoji dalis skirta literatūros apžvalgos ir tyrimo rezultatų skirtumų ir panašumų palyginimui. Tyrimo metu iš gyvūnų augintinių nosies ertmės ir tiesiosios žarnos išskirti Staphylococcus aureus bei Staphylococcus pseudintermedius. Nustatyta, kad koaguliazei teigiamų stafilokokų paplitimas gyvūnų augintinių tarpe priklauso nuo gyvūnų... [toliau žr. visą tekstą]
The The goal of the study: to determine prevalence of coagulase positive staphylococci in companion animals. The aim of the study: 1. to isolate coagulase positive staphylococci in nasal cavity of companion animals; 2. to isolate coagulase positive staphylococci in rectum of companion animals; 3. to identificate the isolated strains of staphylococci; 4. to evaluate risk factors for prevalence of staphylococci; 5. to determine antibiotic resistance in isolated staphylococci. The master study consists of 50 pages. It includes 6 tables and 14 pictures. The master study consist of 4 major chapters. The first chapter is dedicated to review of literature that is related with analized topic. This part includes coagulase positive staphylococci virulence factors, antibiotic resistance, diseases caused by staphylococci and treatment use. Furthermore chapter contains review of the prevalence and risk factors influenced the prevalence of Staphylococcus aureus and Staphylococcus pseudintermedius. The second chapter introduce with materials and methods, that were used in the research at this master study. In the third chapter the results of the research are presented. The results are presented according to the statistical reliability. The fourth chapter is the resemblance and similarity comparision of the literature review and master study research. In this master study Staphylococcus aureus and Staphylococcus pseudintermedius were isolated from nasal cavity and rectum of companion... [to full text]

4

Nilsdotter, Åsa. „Coagulase-negative staphylococci in prosthetic hip infections /“. Linköping : Univ, 2005. http://www.bibl.liu.se/liupubl/disp/disp2005/med902s.pdf.

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5

Pacheco, Diana Isabel Ferreira. „Clínica e cirurgia em bovinos de aptidão leiteira: fatores de risco associados à prevalência de Staphylococcus spp. e coliformes no leite do tanque de explorações da Ilha de São Miguel, Açores“. Master's thesis, Universidade de Évora, 2015. http://hdl.handle.net/10174/15906.

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O presente relatório teve como base o estágio curricular em Clínica e Cirurgia de bovinos de aptidão leiteira realizado na Associação de Jovens Agricultores Micaelenses. A primeira parte deste relatório inclui a compilação da casuística acompanhada, seguida da segunda parte que corresponde à revisão bibliográfica sobre a mastite bovina. A terceira e última parte refere-se ao estudo desenvolvido em 100 explorações leiteiras da ilha de São Miguel, Açores. Do total das amostras de leite do tanque recolhidas nas explorações, 59% foram positivas a Staphylococcus aureus, 100% a Staphylococcus coagulase-negativos, 75% foram positivas a Escherichia coli e 35% a outros coliformes. Alguns dos fatores de risco em estudo, tais como a utilização de luvas e o pré-dipping, foram significativamente associados à prevalência dos agentes acima citados no leite do tanque. Verificou-se ainda uma influência significativa do Staphylococcus aureus na contagem de células somáticas no leite do tanque (P <0,001); DAIRY CATTLE MEDICINE AND SURGERY Risk factors associated with the bulk-milk prevalence of Staphylococcus spp. and coliforms in dairy farms of São Miguel Island, Azores ABSTRACT: This report concerns to the academic internship in dairy cattle Medicine and Surgery performed at Associação de Jovens Agricultores Micaelenses. The first part of the report includes the compilation of accompanied casuistry, followed by the literature revision on bovine mastitis. The third and last part refers to a study in 100 dairy farms of São Miguel Island, Azores - Portugal. From the total bulk tank milk samples collected in the study dairy farms, 59% were positive to Staphylococcus aureus, 100% to coagulase-negative Staphylococci, 75% were positive to Escherichia coli and 35% to other coliforms. Several risk factors in study, such as gloves use and pré-dipping, were significantly associated with the prevalence of the agents mentioned above in bulk tank milk. Moreover, the study revealed a significant influence of Staphylococcus aureus in somatic cells count in bulk tank milk (P <0,001).

6

Couto, Natacha. „Insights into the dynamics of methicillin-resistant staphylococci in animals : a focus on Staphylococcus pseudintermedius in dogs“. Doctoral thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2016. http://hdl.handle.net/10400.5/10771.

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Tese especialmente elaborada para a obtenção do grau de Doutor em Ciências Veterinárias, especialidade de Clínica
Staphylococci are a group of bacteria with clinical, agricultural, and economic importance because of their wide range of virulence factors and ability to become resistant to antimicrobials. This thesis has pursued three main objectives: I. Determine the frequency of methicillin-resistant S. aureus (MRSA) strains in several animal species, identify the characteristics of strains present in animals and comparison with human strains MRSA nasal screening was performed in 71 horses and 307 calves, and the observed frequencies were 3% and 2%, respectively. Seventy-four MRSA isolated from 2001 to 2014 were characterized: fourteen spa types, three SCCmec types and three clonal complexes (CC) 5, CC22 and CC398, were found. Most isolates were multidrug-resistant. Fourteen MRSA CC398 strains had qac genes (13 qacG and 1 qacJ), while 4 isolates (three CC5 and one CC22) had insertions in the norA promoter gene. MRSA linages from pets (CC5 and CC22) harboured specific sets of virulence genes and a lower number of resistance genes than CC398 from livestock-animals. II. Reveal antimicrobial/biocide susceptibility patterns/trends and resistance genes in methicillin-resistant staphylococci (MRS) Several antimicrobial resistance patterns and genes were found in MRS from horses. Minimum bactericidal concentrations of biocides chlorhexidine acetate, benzalkonium chloride, triclosan and glutaraldehyde were lower than the recommended in-use concentrations for veterinary medicine, although two MRS carried plasmid-borne qacA and sh-fabI or qacB and qacH-like genes. An investigation on the evolution of resistance to 38 antimicrobials, corresponding mechanisms and molecular characteristics of 644 clinical Staphylococcus spp. isolates obtained from companion animals between 1999-2014 revealed resistance to the majority of antimicrobials and the number of mecA-positive strains increased significantly over time. Considering S. pseudintermedius, the methicillin-susceptible (MSSP) were genetically more diverse than methicillin-resistant (MRSP). All MRSP and two MSSP strains were multidrug- resistant, with several antimicrobial resistance genes identified. One MSSP isolate harbored a qacA and another a qacB gene. Three biocide products had high bactericidal activity (Otodine®, Clorexyderm Spot Gel®, Dermocanis Piocure-M®), while Skingel® failed to achieve a five log reduction in the bacterial counting. III. Study of the pathogenesis of S. pseudintermedius in dogs The agr type III predominated in MRSP. Five virulence genes were found in all strains and only spsO gene was significantly associated with MSSP. MSSP produced more biofilm on BHIB and BHIB+1% glucose than MRSP isolates. Several virulence genes encoding surface proteins and toxins were highly expressed in the MRSP strain (compared to MSSP). By whole proteome characterization of S. pseudintermedius through 2DE MALDI-TOF/TOF MS approach we were able to identify 367 unique proteins, of which 39 were surface proteins. By subsequent use of the serological proteome analysis (SERPA) approach we identified 4 antigenic proteins with promising features for vaccine development. These results indicate that MRS were widely disseminated in the studied animal population, the environment and people in contact with these animals. The resistant trends and mechanisms detected in MRS strains are worrying and make animals a reservoir of important MRS clones and genes. Biocides are still a good therapeutic choice, even in the presence of efflux genes. Higher expression of virulence genes may play a role in the rapid and widespread of MRSP clones. Dogs are able to mount an IgG-response against S. pseudintermedius and the proteins identified by the immune system can in the future be used as vaccine candidates.
RESUMO - Estudo da dinâmica de estafilococos meticilina-resistente em animais – um foco no Staphylococcus pseudintermedius em cães - Os estafilococos são um grupo de bactérias com importância clínica, agrícola e económica devido à ampla gama de fatores de virulência e pela sua capacidade de se tornarem resistentes aos antimicrobianos. Esta tese debruçou-se sobre três objetivos principais: I. Determinar a frequência de estirpes S. aureus meticilina-resistente (MRSA) em diversas espécies animais, identificar as características das estirpes presentes em animais e comparar com estirpes humanas Colhemos zaragatoas de 71 cavalos e 307 vitelos para pesquisa de MRSA, e observaramse frequências de 3% e 2%, respetivamente. Foram caracterizadas setenta e quatro estirpes MRSA isoladas entre 2001-2014: catorze tipos de spa, três tipos de SCCmec e três complexos clonais (CC) 5, CC22 e CC398, foram encontrados. A maioria das estirpes (74%) eram multirresistentes. Catorze estirpes de MRSA CC398 tinha genes qac (13 qacG e 1 qacJ), enquanto 4 (três CC5 e um CC22) tinham inserções no gene promotor norA. As linhagens de MRSA de animais de estimação (CC5 e CC22) tinham conjuntos específicos de genes de virulência e um menor número de genes de resistência do que as linhagens associadas aos animais de produção (CC398). II. Revelar padrões/ tendências de suscetibilidade antimicrobiana/biocida e genes de resistência em estafilococos meticilina-resistente (MRS) Foram encontrados vários padrões e genes de resistência antimicrobiana em MRS de cavalos. As concentrações bactericidas mínimas dos biocidas acetato de clorhexidina, cloreto de benzalcónio, triclosan e glutaraldeído foram menores do que as recomendadas em medicina veterinária, embora dois MRS tivessem os genes plasmídicos qacA e sh-fabI ou qacB e um qacH-semelhante. Uma investigação sobre a evolução da resistência a 38 antimicrobianos, mecanismos correspondentes e características moleculares de 644 Staphylococcus spp. clínicos obtidos de animais de companhia entre 1999-2014 revelou resistência à maioria dos antimicrobianos. O número de estirpes mecA-positivo aumentou significativamente ao longo do tempo. Quanto aos S. pseudintermedius, os meticilina-suscetível (MSSP) eram geneticamente mais diversos do que os meticilina-resistente (MRSP). Todos os MRSP e 2 MSSP eram multirresistentes, com vários genes de resistência identificados. Um MSSP tinha um gene qacA e outro um qacB. Três produtos biocidas tinham elevada atividade bactericida (Otodine®, Clorexyderm Spot Gel®, Dermocanis Piocure-M®), enquanto Skingel® não conseguiu atingir uma redução de 5 log na contagem bacteriana. III. Estudo da patogenicidade de S. pseudintermedius em cães O tipo III agr predominou nos MRSP. Cinco genes de virulência foram encontrados em todas as estirpes e só o gene spsO foi significativamente associado com MSSP. MSSP produziu mais biofilme em BHIB e BHIB + 1% glucose que as estirpes de MRSP. Vários genes de virulência que codificam proteínas e toxinas de superfície foram altamente expressos na estirpe MRSP (em comparação com MSSP). Através da caracterização do proteoma total de S. pseudintermedius pela abordagem 2DE MALDI-TOF/TOF MS fomos capazes de identificar 367 proteínas únicas, das quais 39 eram proteínas de superfície. Posteriormente utilizámos a análise do proteoma serológico (SERPA) que identificou quatro proteínas antigénicas com características promissoras para o desenvolvimento de vacinas. Estes resultados indicam que MRS estavam amplamente disseminados na população animal estudada, no ambiente e nas pessoas em contato com esses animais. As tendências de resistência e os mecanismos detetados em estirpes MRS são preocupantes tornando os animais um reservatório de clones MRS e genes. Os biocidas ainda são uma boa opção terapêutica, mesmo na presença de bombas de efluxo. Uma maior expressão de genes de virulência pode desempenhar um papel na rápida expansão de clones de MRSP. Os cães foram capazes de montar uma resposta IgG contra S. pseudintermedius e as proteínas identificadas pelo sistema imunológico podem, no futuro, ser utilizadas como candidatos vacinais.

7

Amiali, Mohamed Nassim. „Identification of antibiotic-resistant staphylococci and epidemiological typing of methicillin-resistant Staphylococcus aureus by Fourier transform infrared spectroscopy“. Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19525.

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Staphylococci strains are among the most widespread multidrug-resistant nosocomial pathogens in Canada. Rapid and accurate identification and epidemiological typing of methicillin-resistant S. aureus (MRSA) and its discrimination from coagulase-negative staphylococci (CNS) and glycopeptide-intermediate S. aureus (GISA) are crucial for appropriate therapy and for monitoring and limiting intra- and inter-hospital spread of epidemic MRSA strains. Although pulsed-field gel electrophoresis and polymerase chain reaction methods for the identification of MRSA are reliable, they are technically demanding, time-consuming and inappropriate for routine clinical diagnosis. Moreover, no reliable method exists for discrimination of epidemic MRSA from sporadic MRSA and from GISA strains. The objective of the research described in this thesis was to investigate whether Fourier transform infrared (FTIR) spectroscopy could be used to distinguish MRSA from methicillin-susceptible S. aureus, borderline oxacillin-resistant S. aureus (BORSA), CNS, including methicillin-resistant CNS, and GISA. The application of FTIR spectroscopy for epidemiological typing of Canadian epidemic MRSA (CMRSA) strains as well as their discrimination from sporadic MRSA was also assessed. FTIR spectra were recorded from intact stationary-phase cells grown on Universal Medium (UM™) and deposited and dried on a ZnSe optical window, normalized, and converted to first-derivative spectra. Various chemometric approaches were employed to cluster the different phenotypes of staphylococci species and to subtype five CMRSA strains based on the similarity of their infrared spectral fingerprints in narrow spectral regions selected by visual inspection and by employing a singularvalue decomposition (SVD) algorithm. Pairwise separation of MRSA from MSSA, BORSA, CNS, MRCNS, and GISA was accomplished by using principal component analysis (PCA), self-organizing maps (SOM), and the K-nearest neighbors (KNN) algorithm. These chemometric techniques were also successfully employed for epidemiological typing of the five CMRSA strains and their discrimination from sporadic MRSA strains using a combination of different optimal spectral regions selected by SVD. These results demonstrate that FTIR spectroscopy has considerable potential as a rapid method for the identification of different phenotypes of staphylococci and epidemiological typing of MRSA.

8

Holt-Torres, Patricia. „Anti-Staphylococcal Activity of Variovorax paradoxus EPS“. CSUSB ScholarWorks, 2017. https://scholarworks.lib.csusb.edu/etd/584.

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Variovorax paradoxus EPS is a gram-negative rod isolated from the sunflower rhizosphere at CSUSB. Preliminary research has shown that Variovorax paradoxus EPS has anti-staphylococcal activity in liquid and solid co-culture. Anti-staphylococcal activity of Wild type and V. paradoxus EPS 𝚫4519 on 0.5% YE agar with embedded S. aureus AH1710 supports the idea that a soluble molecule is responsible for this activity, as the agar acted as a physical barrier between V. paradoxus EPS and S. aureus colonies. Preliminary genetic analysis of V. paradoxus EPS identified three loci that suitable candidates for the synthesis of a potential anti-staphylococcal small molecule. Preliminary data failed to detect expression at two of the three identified loci and a strain with a mutation at the third locus continues to produce anti-staphylococcal activity. We hypothesize that the microbial agent is expressed at a different locus or loci that have not yet been identified. These gene products are responsible for the synthesis of the microbial agent and are controlled by exposure to Staphylococcus aureus. Optimal growth conditions were identified for V. paradoxus EPS and S. aureus to demonstrate the formation of a zone of inhibition on Tryptic Soy Agar. The use of a V. paradoxus EPS Δ 4519 transposon library at optimal growth conditions allowed us candidate mutants with altered antimicrobial activity phenotypes. We identified 28 insertion sites that resulted in altered antimicrobial activities, which will allow us to identify the genes involved in this biosynthetic pathway.

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Motta, Rogério Heládio Lopes. „Prevalencia, resistencia e patogenicidade de Staphylococcus aureus colhidos no ambiente clinico odontologico“. [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290193.

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Orientadores : Thales Rocha de Mattos Filho, Francisco Carlos Groppo
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
Made available in DSpace on 2018-08-04T03:41:21Z (GMT). No. of bitstreams: 1 Motta_RogerioHeladioLopes_D.pdf: 659292 bytes, checksum: 254fb5f4f10c3501c081c5129d2db30f (MD5) Previous issue date: 2005
Doutorado
Farmacologia, Anestesiologia e Terapeutica
Doutor em Odontologia

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Björkqvist, Maria. „Coagulase-negative staphylococci septicaemia in newborns : aspects on host-bacterial interactions with special regard to neutrophil and endothelial response /“. Linköping : Univ, 2004. http://www.bibl.liu.se/liupubl/disp/disp2004/med861s.pdf.

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Bücher zum Thema "Staphylococcic":

1

Allen, Honeyman, Friedman Herman 1931- und Bendinelli Mauro, Hrsg. Staphylococcus aureus infection and disease. New York: Kluwer Academic/Plenum, 2001.

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2

International Symposium on Staphylococci and Staphylococcal Infections (5th 1984 Warsaw, Poland). The staphylococci: Proceedings of V International Symposium on Staphylococci and Staphylococcal Infections : Warszawa, June 26-30, 1984. Herausgegeben von Jeljaszewicz J. Stuttgart: G. Fischer, 1985.

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B, Crossley Kent, und Archer Gordon 1943-, Hrsg. The staphylococci in human disease. New York: Churchill Livingstone, 1997.

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Fey, Paul D. Staphylococcus epidermidis: Methods and protocols. New York: Humana Press, 2014.

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V, Smirnov V., Vershigora A. E und Instytut mikrobiolohiï im. virusolohiï D.K. Zabolotnoho., Hrsg. Stafilokokk: Biologicheski aktivnye substant͡s︡ii, immunnyĭ otvet na antigeny. Kiev: Nauk. dumka, 1988.

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B, Crossley Kent, Hrsg. Staphylococci in human disease. 2. Aufl. Chichester, West Sussex: Wiley-Blackwell, 2010.

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Weller, Timothy Mark Atticus. The expression of Methicillin-resistance in Staphylococcus Aureus and coagulase-negative Staphylococci. Birmingham: University of Birmingham, 1998.

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Geary, Colin. Staphylococci: Aspects of classification, pathogenesis and epidemiological typing, with special reference to staphylococcus epidermidis. Leicester: De Montfort University, 1994.

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Ji, Yinduo. Methicillin-resistant staphylococcus aureus (MRSA) protocols. New York: Springer, 2014.

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Maurice, Rapin Colloquia (4th 1994 Les Baux-de-Provence France). Methicillin resistant staphylococci. Paris: Flammarion médecine-sciences, 1995.

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Buchteile zum Thema "Staphylococcic":

1

Tristan, Anne, Gerard Lina, Jerome Etienne und François Vandenesch. „Biology and Pathogenicity of Staphylococci Other than Staphylococcus aureus and Staphylococcus epidermidis“. In Gram-Positive Pathogens, 572–86. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555816513.ch47.

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Evans, James B. „Staphylococci“. In Advances in Meat Research, 231–39. London: Macmillan Education UK, 1986. http://dx.doi.org/10.1007/978-1-349-09145-4_8.

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Lindsay, Jodi A. „Staphylococci“. In Molecular Typing in Bacterial Infections, 385–405. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-185-1_23.

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McClure, JoAnn M., und Kunyan Zhang. „Staphylococci“. In Molecular Typing in Bacterial Infections, Volume II, 169–92. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-83217-9_9.

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Hermans, K., L. A. Devriese und F. Haesebrouck. „Staphylococcus“. In Pathogenesis of Bacterial Infections in Animals, 75–89. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9780470958209.ch5.

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Zhang, Mingjuan Lisa. „Staphylococcus“. In Encyclopedia of Ophthalmology, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-35951-4_709-1.

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Zhang, Mingjuan Lisa. „Staphylococcus“. In Encyclopedia of Ophthalmology, 1672. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-540-69000-9_709.

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Novick, Richard. „Staphylococcus“. In Bacillus subtilis and Other Gram-Positive Bacteria, 17–33. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818388.ch2.

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Rodríguez, Mar, Alicia Rodríguez, María Jesús Andrade, Elena Bermúdez und Juan José Córdoba. „Staphylococcus“. In Laboratory Models for Foodborne Infections, 209–21. Boca Raton : CRC Press/Taylor & Francis, 2017. | Series: Food microbiology series: CRC Press, 2017. http://dx.doi.org/10.1201/9781315120089-13.

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Bradley, Suzanne F. „Staphylococcus“. In Schlossberg's Clinical Infectious Disease, herausgegeben von Cheston B. Cunha, 992–96. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190888367.003.0149.

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This chapter looks at the treatment of staphylococcal infection that is dependent on the site involved, the severity of infection, and the antibiotic susceptibility pattern of the organism causing the infection. It discusses the most serious staphylococcal infections that are caused by coagulase-positive staphylococci and coagulase-negative staphylococci, which may be life threatening. It also describes Staphylococcus aureus as a highly invasive pathogen that spreads hematogenously to many organs and leads to metastatic foci of infection. The chapter investigates coagulase-negative staphylococci, which are generally healthcare-associated infections that require the presence of prosthetic material to gain a foothold and cause infection. It explains staphylococci's quick propensity to develop resistance to antibiotics.

Konferenzberichte zum Thema "Staphylococcic":

1

Charfi, Manel, Amel Ben Hamad, Rim Abdelkrim, Chiraz Regaieg, Amira Bouraoui, Ridha Regaieg, Nedia Hmida, Afef Ben Thabet und abdellatif Gargouri. „P622 Staphylococcic necrotizing pneumonia in a two months infant“. In Faculty of Paediatrics of the Royal College of Physicians of Ireland, 9th Europaediatrics Congress, 13–15 June, Dublin, Ireland 2019. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2019. http://dx.doi.org/10.1136/archdischild-2019-epa.953.

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Kiranasari, Ariyani, Angela Bonita, Elizabeth Melina, Kevin Winston, Naivedh Baht, Nathania Sutandi, Beti Ernawati Dewi, Ika Ningsih und Fithriyah Sjatha. „Antibacterial Activity of Several Indonesian Endemic Plants against Staphylococcus epidermidis, Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus“. In Bromo Conference, Symposium on Natural Products and Biodiversity. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0008359501780182.

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Omar Mohammed, Mohammed Shaymaa, Nicoleta Radu, Verginica Schroder, Rodica Roxana Constantinescu und Narcisa Babeanu. „Antimicrobial Properties of the Bioproducts Formulated with Chitosan and Collagen“. In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.ii.17.

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Three types of formulations (stable suspensions) based on collagen, chitosan, limonene and an imidazole derivative were studied through in vitro tests, from the point of view of antimicrobial activity. The results obtained on 4 standardized microorganisms, namely Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Staphylococcus aureus MRSA, Candida albicans, demonstrated that most of the obtained bioproducts have a local effect (inhibition diameters below 15 mm are obtained) and moderate effect (inhibition diameters located under 20 mm), except bioproducts containing collagen, chitosan, limonene and an imidazole derivative (antibiotic reagent) in mass ratio Col:Chit:Lim:CT=1:1:1:0.1, Col:Chit:Lim:CT=1:1:0:0.1 which exhibit a significant antimicrobial effect on Staphylococcus aureus and Staphylococcus aureus MRSA. These two formulations also exhibit significant antimicrobial effects for Candida albicans, for which the average inhibition diameters obtained are greater than 34 mm.

4

Rogachev, M. I., und N. M. Kolokolova. „METHODS OF STUDYG STAPHYLOCOCCAL INFECTION“. In Основные вопросы лингвистики, лингводидактики и межкультурной коммуникации. Астрахань: Астраханский государственный университет, 2022. http://dx.doi.org/10.54398/20751699_2022_157.

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Saptana, Yosefin Ida, Riski Sulistiarini und Rolan Rusli. „AKTIVITAS ANTIBAKTERI GEL EKSTRAK KECOMBRANG (ETLINGERA ELATIOR) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS DAN STAPHYLOCOCCUS EPIDERMIDIS“. In Mulawarman Pharmaceuticals Conferences. Fakultas Farmasi, Universitas Mulawarman, Samarinda, 2015. http://dx.doi.org/10.25026/mpc.v2i1.51.

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Mühlmeier, G., und M. Tisch. „Intracellular staphylococci in chronic sinusitis - serologic detection“. In Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1711385.

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Himelbloom, B. H. „Staphylococcus aureus concerns in smoked fish“. In International Smoked Seafood Conference. Alaska Sea Grant, University of Alaska Fairbanks, 2008. http://dx.doi.org/10.4027/isscp.2008.03.

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Adams, Kelly M., Valsamma Abraham, Daniel Spielman, Noam Cohen, Jay K. Kolls und James L. Kreindler. „Pendrin Expression In Staphylococcus Aureus Pneumonia“. In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3532.

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Blajan, Marius, Ahmad Guji Yahaya, Jaroslav Kristof, Tomohiro Okuyama und Kazuo Shimizu. „Inactivation of Staphylococcus Aureus by Microplasma“. In 2021 IEEE Industry Applications Society Annual Meeting (IAS). IEEE, 2021. http://dx.doi.org/10.1109/ias48185.2021.9677085.

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Jamil, Alia Hussein, Ali Abdulhussien und Mohammad Alsharifi. „The anti-biofilm activity of lemon oil against methicillin resistance of Staphylococcus aureus and Staphylococcus haemolyticus“. In 3RD INTERNATIONAL SCIENTIFIC CONFERENCE OF ALKAFEEL UNIVERSITY (ISCKU 2021). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0067569.

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Berichte der Organisationen zum Thema "Staphylococcic":

1

Leitner, Gabriel, und Naomi Balaban. Novel Immunotherapeutic Agent for the Treatment and Prevention of Staphylococcal Mastitis in Dairy Cows. United States Department of Agriculture, Januar 2009. http://dx.doi.org/10.32747/2009.7709880.bard.

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Staphylococci are the most common and costly mammary disease of dairy cattle worldwide. TRAP, a membrane associated 167AA protein, is highly conserved among staphylococci. The aims of this study were to test the safety and efficacy of recombinant TRAP (rTRAP) vaccine in dairy animals. The vaccine was safe as 2-3 subcutaneous injections of rTRAP (54–100μg) with adjuvant ISA 206 to cows and goats did not lead to any abnormal symptoms of sensitivity to the vaccine. The rTRAP vaccine was immunogenic and caused the induction of a humoral immune response that remained high for at least 160 days post second immunization. rTRAP vaccine also elicited a cell-mediated immune response (memory CD4+ and CD8+ T cells), as determined by lymphocyte proliferation assays. The rTRAP vaccine was efficacious as at parturition, only 13.5% heifers in the immunized group were infected with Staphylococcus chromogenes as compared to 42.9% in the non immunized group. Additionally, when cows were immunized in mid-lactation, the difference between somatic cell count (SCC) in immunized and control animals was profound (45±7 vs. 470±194, respectively). At the same time, the difference in milk yield was also evident (48.3±1.4 vs. 44.3±0.9 l/day, respectively). Put together, these studies indicate the value of the rTRAP vaccine in preventing new udder infections by staphylococci, which significantly lead to lowered SCC and some increase in milk yield. TRAP is conserved among all strains and species and is constitutively expressed in any strain of S. aureus or CNS tested so far, including those isolated from cows. TRAP may thus serve as a universal anti-staphylococcus vaccine.

2

Leitner, Gabriel, und Naomi Balaban. Novel Immunotherapeutic Agent for the Treatment and Prevention of Staphylococcal Mastitis in Dairy Cows. United States Department of Agriculture, Januar 2009. http://dx.doi.org/10.32747/2009.7695866.bard.

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Staphylococci are the most common and costly mammary disease of dairy cattle worldwide. TRAP, a membrane associated 167AA protein, is highly conserved among staphylococci. The aims of this study were to test the safety and efficacy of recombinant TRAP (rTRAP) vaccine in dairy animals. The vaccine was safe as 2-3 subcutaneous injections of rTRAP (54–100μg) with adjuvant ISA 206 to cows and goats did not lead to any abnormal symptoms of sensitivity to the vaccine. The rTRAP vaccine was immunogenic and caused the induction of a humoral immune response that remained high for at least 160 days post second immunization. rTRAP vaccine also elicited a cell-mediated immune response (memory CD4+ and CD8+ T cells), as determined by lymphocyte proliferation assays. The rTRAP vaccine was efficacious as at parturition, only 13.5% heifers in the immunized group were infected with Staphylococcus chromogenes as compared to 42.9% in the non immunized group. Additionally, when cows were immunized in mid-lactation, the difference between somatic cell count (SCC) in immunized and control animals was profound (45±7 vs. 470±194, respectively). At the same time, the difference in milk yield was also evident (48.3±1.4 vs. 44.3±0.9 l/day, respectively). Put together, these studies indicate the value of the rTRAP vaccine in preventing new udder infections by staphylococci, which significantly lead to lowered SCC and some increase in milk yield. TRAP is conserved among all strains and species and is constitutively expressed in any strain of S. aureus or CNS tested so far, including those isolated from cows. TRAP may thus serve as a universal anti-staphylococcus vaccine.

3

Sax, Martin, J. Pletcher und S. Swaminathan. The 3D Structure of Staphylococcal Enterotoxins. Fort Belvoir, VA: Defense Technical Information Center, Oktober 1994. http://dx.doi.org/10.21236/ada286091.

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Sax, M., J. Pletcher und S. Swaminathan. The 3-D Structure of Staphylococcal Enterotoxins. Fort Belvoir, VA: Defense Technical Information Center, Oktober 1995. http://dx.doi.org/10.21236/ada300618.

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Sordillo, Lorraine, Don Wojchowski, Gary Perdew, Arthur Saran und Gabriel Leitner. Identification of Staphylococcus aureaus Virulence Factors Associated with Bovine Mastitis. United States Department of Agriculture, Februar 2001. http://dx.doi.org/10.32747/2001.7574340.bard.

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Staphylococcus aureus is a major cause of mastitis in dairy cattle. The organism is able to adhere to and penetrate mammary epithelium, forming deep seated abscesses that result in chronic infections. This study was based on the observation that certain genotypes of S. aureus are isolated more frequently from field cases of bovine mastitis than others and the most prevalent genotypes of S. aureus have an increased ability to resist neutrophil phagocytosis and killing compared to the rare variants. It was hypothesized that these predominating genotypes differentially express virulence factors that allow them to overcome or suppress essential host defense mechanisms and successfully colonize mammary parenchyma. The overall objective of this study was to determine the mechanisms by which predominating S. aureus genotypes were able to resist mammary gland defense mechanisms. The following specific aims were accomplished to address the overall objectives of this project: 1. Analyze and compare cell surface and secreted protein profiles of common and rare S. aureus genotypes isolated from field cases of bovine mastitis. 2. Purify and sequence selectively synthesized proteins unique to the most prevalent genotypes of S. aureus . 3. Determine the in vitro effects of isolated proteins on essential host defense mechanisms. Results from each specific aim showed that these redominating genotypes differentially express factors that may allow them to overcome or suppress essential host defense mechanisms and successfully colonize mammary parenchyma. Using complementary approaches, both the US and Israeli teams identified differentially expressed S. aureus factors that were positively correlated with virulence as determined by the ability to modify host immune cell responses and increase disease pathogenesis. Several candidate virulence factors have ben identified at both the molecular (US team) and protein (Israeli team) levels. Components of the phosphotransferase system were shown to be differentially expressed in prevalent strains of S. aureus and to modify the growth potential of these strains in a milk microenvironment. Evidence provided by both the Israeli and US teams also demonstrated a potential role of Staphylococcal enterotoxins in the pathogenesis of mastitis. Certain enterotoxins were shown to directly affect neutrophil bactericidal activities which can profoundly affect the establishment of new intramammary infections. Other evidence suggests that S. aureus superantigens can suppress mammary defenses by enhancing lymphoid suppressor cell activity. Collectively, these data suggest that unique factors are associated with predominating S. aureus genotypes that can affect in vitro and in vivo virulence as related to the pathogenesis of bovine mastitis. The potential development of a subunit mastitis vaccine which incorporates only relevant antigenic determinants has not been investigated in depth. Experiments outlined in this proposal has identified putative virulence factors which contribute to the pathogenesis of S. aureus mastitis and which may be used to formulate an efficacious subunit mastitis vaccine. Results from these studies may lead to the development of new methods to prevent this costly disease, providing a viable alternative to less effective mastitis control procedures based on chemotherapy.

6

Sadeghi, Abbas. Development of a Semi-synthetic Medium Supporting Adherent Growth in Coagulase-Negative Staphylococci. Portland State University Library, Januar 2000. http://dx.doi.org/10.15760/etd.13.

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Smeltzer, Mark S. sarA as a Target for the Treatment and Prevention of Staphylococcal Biofilm-Associated Infection. Fort Belvoir, VA: Defense Technical Information Center, Oktober 2012. http://dx.doi.org/10.21236/ada576194.

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Smeltzer, Mark S. sarA as a Target for the Treatment and Prevention of Staphylococcal Biofilm-Associated Infection. Fort Belvoir, VA: Defense Technical Information Center, Oktober 2013. http://dx.doi.org/10.21236/ada590817.

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Smeltzer, Mark S. sarA as a Target for the Treatment and Prevention of Staphylococcal Biofilm-Associated Infection. Fort Belvoir, VA: Defense Technical Information Center, Februar 2015. http://dx.doi.org/10.21236/ada621335.

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Spencer, Jessica, und Uzo Chukwuma. Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in the Department of Defense (DOD): Annual Summary 2013. Fort Belvoir, VA: Defense Technical Information Center, Januar 2015. http://dx.doi.org/10.21236/ada612614.

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