Bücher zum Thema „Stain transfer“

Statin myopathy can occur at anytime during use. This chapter discusses an approach to diagnosis, and emphasizes management considerations, including awareness of statin metabolism by the cytochrome P-450 system. A statin must be discontinued in any patient with evidence of myopathy or myalgias. A muscle biopsy should be done in cases that do not improve clinically or by creatine kinase level. It is important to note that there are cases of apparent statin myopathy which transform into a chronic autoimmune inflammatory myopathy. Antibodies to hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase have recently been identified in the majority of patients with autoimmune statin myopathy and this test may give further weight to treat with immunotherapy.

This book reveals how the vast Soviet penal system was reimagined and reformed in the wake of Stalin's death. The text argues that penal reform in the 1950s was a serious endeavor intended to transform the Gulag into a humane institution that re-educated criminals into honest Soviet citizens. Under the leadership of Minister of Internal Affairs Nikolai Dudorov, a Khrushchev appointee, this drive to change the Gulag into a “progressive” system where criminals were reformed through a combination of education, vocational training, leniency, sport, labor, cultural programs, and self-governance was both sincere and at least partially effective. The new vision for the Gulag faced many obstacles. Re-education proved difficult to quantify, a serious liability in a statistics-obsessed state. The entrenched habits of Gulag officials and the prisoner-guard power dynamic mitigated the effect of the post-Stalin reforms. And the Soviet public never fully accepted the new policies of leniency and the humane treatment of criminals. In the late 1950s, they joined with a coalition of party officials, criminologists, procurators, newspaper reporters, and some penal administrators to rally around the slogan “The camp is not a resort” and succeeded in re-imposing harsher conditions for inmates. By the mid-1960s the Soviet Gulag had emerged as a hybrid system forged from the old Stalinist system, the vision promoted by Khrushchev and others in the mid-1950s, and the ensuing counter-reform movement. This new penal equilibrium largely persisted until the fall of the Soviet Union.

Schule ist ein zentraler Ort für die Prävention sexualisierter Gewalt und die Vermittlung Sexueller Bildung. Das BMBF-Forschungsprojekt »SeBiLe – Sexuelle Bildung für das Lehramt« hat jedoch gezeigt, dass Lehrkräfte in Deutschland in beiden Bereichen nicht ausreichend aus- und fortgebildet werden. Die Herausgeberinnen präsentieren die Ergebnisse der dreijährigen empirischen Forschung des Projekts SeBiLe und betten sie mithilfe der Beitragenden in den fachspezifischen Diskurs ein. Kernstück des Bandes ist ein daraus entwickeltes praxisorientiertes Curriculum, das Anregung zur Umsetzung konkreter Inhalte in der Lehramtsaus- und fortbildung bietet. So ermöglichen die Autor:innen einen direkten Transfer der im Projekt gewonnenen Erkenntnisse in die Aus- und Fortbildung von Lehramtsstudierenden und Lehrer:innen und zeigen verbliebene Handlungsbedarfe in Forschung und Praxis auf. Mit Beiträgen von C. Bergmann, S. Berndt, A. de Silva, B. Drinck, H. Holz, N. Kallweit, J. Keitel, C. Khamis, B. Kollinger, E. Kubitza, L. Lache, S. Maschke, A. Meyer, H. Paech, D. Pech, B. Proll, P. Scheibelhofer, A. Schmidt, J.K.M. Siemoneit, T. Simon, L. Stecher, J.W. Stein, M. Urban, H.-J. Voß, A. Weist, S. Wienholz und D. Zimmermann.

At a conference on developing the capacity of systems biology to transform itself in systems biomedicine, several of the scientists’ presentations showcase the computational modelling methods they are developing. Drawing towards the end of his presentation, an experienced pharmacologist admonishes the audience to bear in mind that, despite the progress in modelling techniques that he has been discussing, a model is always just a representation and never reality. At this point, there is a PowerPoint slide showing Magritte’s painting, This is not a Pipe, and chuckling from the audience. It will not have been the first time that they have seen it, as the painting is by now a trope running through these events, rivalled only by the quotation from George Box: ‘Essentially all models are wrong, but some are useful.’ Indeed, I have taken up this trope myself, but find that I need to judge my audience carefully when choosing what to move on with. ‘On Exactitude in Science’, but more problematic is to follow up with Picasso’s portrait of Gertrude Stein, together with the quotation attributed to Picasso: ‘Everybody says that she does not look like it but that does not make any difference, she will.’

Operating between film theory, media philosophy, archival practice, and audiovisual research, Jirí Anger focuses on the relationship between figuration and materiality in early films, experimental found footage cinema, and video essays. Would it be possible to do film theory from below, through the perspective of moving-image objects, of their multifarious details and facets, however marginal, unintentional, or aleatory they might be? Could we treat scratches, stains, and shakes in archival footage as speculatively and aesthetically generative features? Do these material actors have the capacity to create “weird shapes” within the figurative image that decenter, distort, and transform the existing conceptual and methodological frameworks? Building on his theoretical as well as practical experience with the recently digitized corpus of the first Czech films, created by Jan Kríženecký between 1898 and 1911, the author demonstrates how technological defects and accidents in archival films shape their aesthetic function and our understanding of the materiality of film in the digital age. The specific clashes between the figurative and material spheres are understood through the concept of a “crack-up.” This term, developed by Francis Scott Fitzgerald and theoretically reimagined by Gilles Deleuze, allows us to capture the convoluted relationship between figuration and materiality as inherent to the medium of film, containing negativity and productivity, difference and simultaneity, contingency and fate, at the same time, even within the tiniest cinematic units.

A graduate-level text, Semiconductor physics: Principles, theory and nanoscale covers the central topics of the field, together with advanced topics related to the nanoscale and to quantum confinement, and integrates the understanding of important attributes that go beyond the conventional solid-state and statistical expositions. Topics include the behavior of electrons, phonons and photons; the energy and entropic foundations; bandstructures and their calculation; the behavior at surfaces and interfaces, including those of heterostructures and their heterojunctions; deep and shallow point perturbations; scattering and transport, including mesoscale behavior, using the evolution and dynamics of classical and quantum ensembles from a probabilistic viewpoint; energy transformations; light-matter interactions; the role of causality; the connections between the quantum and the macroscale that lead to linear responses and Onsager relationships; fluctuations and their connections to dissipation, noise and other attributes; stress and strain effects in semiconductors; properties of high permittivity dielectrics; and remote interaction processes. The final chapter discusses the special consequences of the principles to the variety of properties (consequences of selection rules, for example) under quantum-confined conditions and in monolayer semiconductor systems. The text also bring together short appendices discussing transform theorems integral to this study, the nature of random processes, oscillator strength, A and B coefficients and other topics important for understanding semiconductor behavior. The text brings the study of semiconductor physics to the same level as that of the advanced texts of solid state by focusing exclusively on the equilibrium and off-equilibrium behaviors important in semiconductors.

Methodism was originally a loosely connected network of religious clubs, each devoted to promoting holy living among its members. It was part of the Evangelical Revival, a movement of religious ideas which swept across the North Atlantic world in the eighteenth century. This chapter charts the growth and development, character and nature, and consolidation and decline of British Methodism in the nineteenth century from five distinct perspectives. First, Methodism grew rapidly in the early nineteenth century but struggled to channel that enthusiasm in an effective way. As a result, it was beset by repeated secessions, and the emergence of rival Methodist groups, each with their own distinctive characteristics, of which Wesleyan Methodism was the largest and most influential. Second, while Methodism grew rapidly in England, it struggled to find a successful footing in the Celtic fringes of Wales, Ireland, and Scotland. Here, local preoccupations, sectarian tensions, and linguistic differences required a degree of flexibility which the Methodist leadership was often not prepared to concede. Third, the composition of the Methodist membership is considered. While it is acknowledged that most Methodists came from working-class backgrounds, it is also suggested that Methodists became more middle class as the century progressed. People were attracted to Methodism because of its potential to transform lives and support people in the process. It encouraged the laity to take leadership roles, including women. It provided a whole network of support services which, taken together, created a self-sufficient religious culture. Fourth, Methodism had a distinctive position within the British polity. In the early nineteenth century the Wesleyan leadership was deeply conservative, and even aligned itself with the Tory interest. Wesleyan members and almost all of Free Methodism were reformist in their politics and aligned themselves with the Whig, later Liberal interest. This early conservatism was the result of Methodism’s origins within the Church of England. As the nineteenth century progressed, this relationship came under strain. By the end of the century, Methodists had distanced themselves from Anglicans and were becoming vocal supporters of Dissenting campaigns for political equality. Fifth, in the late nineteenth century, Methodism’s spectacular growth of earlier decades had slowed and decline began to set in. From the 1880s, Methodism sought to tackle this challenge in a number of ways. It sought to broaden its evangelical message, and one of its core theological precepts, that of holiness. It embarked on an ambitious programme of social reform. And it attempted to modernize its denominational practices. In an attempt to strengthen its presence in the face of growing apathy, several branches of Methodism reunited, forming, in 1932, the Methodist Church in Britain. However, this institutional reorganization could not stop the steady decline of British members into the twentieth century. Instead, Methodism expanded globally, into previously non-Christian areas. It is now a denomination with a significant world presence. British Methodism, however, continues to struggle, increasingly of interest only as a heritage site for the origins of a much wider and increasingly diverse movement.